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Ofelia Olivero

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Kaarthik John; Gail McMullen; Ofelia A Olivero; Igor P Pogribny; Frederick A Beland; Mona I Churchwell; M Margaret Pratt; Miriam C Poirier
Benzo[a]pyrene (BP) DNA adduct formation in DNA repair-deficient p53 haploinsufficient [Xpa(-/-)p53(+/-)] and wild-type mice fed BP and BP plus chlorophyllin for 28 days.
M Margaret Pratt; Leon C King; Linda D Adams; Kaarthik John; Paul Sirajuddin; Ofelia A Olivero; David K Manchester; Radim J Sram; David M DeMarini; Miriam C Poirier
Assessment of multiple types of DNA damage in human placentas from smoking and nonsmoking women in the Czech Republic.
Ofelia A Olivero; Marcelo Larramendy; Sonia Soloneski; Carlos F M Menck; Jaime Matta; Gustavo A Folle; Enrique Zamorano-Ponce; Graciela Spivak
Impact of EMS outreach: successful developments in Latin America.

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2012: Kaarthik John; Gail McMullen; Ofelia A Olivero; Igor P Pogribny; Frederick A Beland; Mona I Churchwell; M Margaret Pratt; Miriam C Poirier
Benzo[a]pyrene (BP) DNA adduct formation in DNA repair-deficient p53 haploinsufficient [Xpa(-/-)p53(+/-)] and wild-type mice fed BP and BP plus chlorophyllin for 28 days.
Carcinogenesis 2012;33(11):2236-41.
2011: M Margaret Pratt; Leon C King; Linda D Adams; Kaarthik John; Paul Sirajuddin; Ofelia A Olivero; David K Manchester; Radim J Sram; David M DeMarini; Miriam C Poirier
Assessment of multiple types of DNA damage in human placentas from smoking and nonsmoking women in the Czech Republic.
Environmental and molecular mutagenesis 2011;52(1):58-68.
2010: Ofelia A Olivero; Marcelo Larramendy; Sonia Soloneski; Carlos F M Menck; Jaime Matta; Gustavo A Folle; Enrique Zamorano-Ponce; Graciela Spivak
Impact of EMS outreach: successful developments in Latin America.
Environmental and molecular mutagenesis 2010;51(8-9):763-73.
2010: Ofelia A Olivero; Irma L Vazquez; Catherine C Cooch; Jessica Ming; Emily Keller; Mia Yu; Jennifer P Borojerdi; Hannan M Braun; Edward McKee; Miriam C Poirier
Long-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cells.
Toxicological sciences : an official journal of the Society of Toxicology 2010;115(1):109-17.
2009: Mia Yu; Yvona Ward; Miriam C Poirier; Ofelia A Olivero
Centrosome amplification induced by the antiretroviral nucleoside reverse transcriptase inhibitors lamivudine, stavudine, and didanosine.
Environmental and molecular mutagenesis 2009;50(8):718-24.
2009: Dale M Walker; Adriana E Kajon; Salina M Torres; Meghan M Carter; Consuelo L McCash; James A Swenberg; Patricia B Upton; Andrew W Hardy; Ofelia A Olivero; Gene M Shearer; Miriam C Poirier; Vernon E Walker
WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication.
Environmental and molecular mutagenesis 2009;50(6):460-72.
2009: Jennifer P Borojerdi; Jessica Ming; Catherine Cooch; Yvona Ward; Cristina Semino-Mora; Mia Yu; Hannan M Braun; Barbara J Taylor; Miriam C Poirier; Ofelia A Olivero
Centrosomal amplification and aneuploidy induced by the antiretroviral drug AZT in hamster and human cells.
Mutation research 2009;665(1-2):67-74.
2009: Laura J Schild-Hay; Tarek A Leil; Rao L Divi; Ofelia A Olivero; Ainsley Weston; Miriam C Poirier
Tamoxifen induces expression of immune response-related genes in cultured normal human mammary epithelial cells.
Cancer research 2009;69(3):1150-5.
2009: Miriam C Poirier; Ofelia A Olivero; Andrew W Hardy; Genoveffa Franchini; Jennifer P Borojerdi; Vernon E Walker; Dale M Walker; Gene M Shearer
Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo.
AIDS research and therapy 2009;6():24.
2008: Ofelia A Olivero; Jessica M Ming; Shreyasi Das; Irma L Vazquez; Diana L Richardson; Ainsley Weston; Miriam C Poirier
Human inter-individual variability in metabolism and genotoxic response to zidovudine.
Toxicology and applied pharmacology 2008;228(2):158-64.
2008: Ofelia A Olivero
Relevance of experimental models for investigation of genotoxicity induced by antiretroviral therapy during human pregnancy.
Mutation research 2008;658(3):184-90.
2007: M Margaret Pratt; Paul Sirajuddin; Miriam C Poirier; Mark Schiffman; Andrew G. Glass; David R Scott; Brenda B Rush; Ofelia A Olivero; Philip E Castle
Polycyclic aromatic hydrocarbon-DNA adducts in cervix of women infected with carcinogenic human papillomavirus types: an immunohistochemistry study.
Mutation research 2007;624(1-2):114-23.
2007: Salina M Torres; Dale M Walker; Meghan M Carter; Dennis L Cook; Consuelo L McCash; Edmund M Cordova; Ofelia A Olivero; Miriam C Poirier; Vernon E Walker
Mutagenicity of zidovudine, lamivudine, and abacavir following in vitro exposure of human lymphoblastoid cells or in utero exposure of CD-1 mice to single agents or drug combinations.
Environmental and molecular mutagenesis 2007;48(3-4):224-38.
2007: Patricia A Escobar; Ofelia A Olivero; Nancy A Wade; Elaine J Abrams; Carol J Nesel; Roberta B Ness; Richard D Day; Billy W Day; Quanxin Meng; J Patrick O'Neill; Dale M Walker; Miriam C Poirier; Vernon E Walker; William L Bigbee
Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother-child pairs to AZT or AZT-3TC.
Environmental and molecular mutagenesis 2007;48(3-4):330-43.
2007: Quanxin Meng; Ofelia A Olivero; Michael J Fasco; Ronald Bellisario; Laurence S Kaminsky; Kenneth A Pass; Nancy A Wade; Elaine J Abrams; Carol J Nesel; Roberta B Ness; William L Bigbee; J Patrick O'Neill; Dale M Walker; Miriam C Poirier; Vernon E Walker
Plasma and cellular markers of 3'-azido-3'-dideoxythymidine (AZT) metabolism as indicators of DNA damage in cord blood mononuclear cells from infants receiving prepartum NRTIs.
Environmental and molecular mutagenesis 2007;48(3-4):307-21.
2007: Rao L Divi; Kathryn J Haverkos; Juliette A Humsi; Marie E Shockley; Chandrasekhar Thamire; Kunio Nagashima; Ofelia A Olivero; Miriam C Poirier
Morphological and molecular course of mitochondrial pathology in cultured human cells exposed long-term to Zidovudine.
Environmental and molecular mutagenesis 2007;48(3-4):179-89.
2007: Ofelia A Olivero
Mechanisms of genotoxicity of nucleoside reverse transcriptase inhibitors.
Environmental and molecular mutagenesis 2007;48(3-4):215-23.
2007: Hilde E van Gijssel; Tarek A Leil; Wendy C Weinberg; Rao L Divi; Ofelia A Olivero; Miriam C Poirier
Cisplatin-DNA damage in p21WAF1/Cip1 deficient mouse keratinocytes exposed to cisplatin.
Mutagenesis 2007;22(1):49-54.
2005: Ofelia A Olivero; Agueda M Tejera; Juan J Fernandez; Barbara J Taylor; Shreyasi Das; Rao L Divi; Miriam C Poirier
Zidovudine induces S-phase arrest and cell cycle gene expression changes in human cells.
Mutagenesis 2005;20(2):139-46.
2005: Maureen R Gwinn; Channa Keshava; Ofelia A Olivero; Juliette A Humsi; Miriam C Poirier; Ainsley Weston
Transcriptional signatures of normal human mammary epithelial cells in response to benzo[a]pyrene exposure: a comparison of three microarray platforms.
Omics : a journal of integrative biology 2005;9(4):334-50.
2004: Miriam C Poirier; Ofelia A Olivero; Dale M Walker; Vernon E Walker
Perinatal genotoxicity and carcinogenicity of anti-retroviral nucleoside analog drugs.
Toxicology and applied pharmacology 2004;199(2):151-61.
2004: Mariana Gerschenson; Vi Nguyen; Ember L Ewings; Andrea Ceresa; Jaclyn A Shaw; Marisa C St Claire; Kunio Nagashima; Steven W Harbaugh; Jeffrey W Harbaugh; Ofelia A Olivero; Rao L Divi; Paul S Albert; Miriam C Poirier
Mitochondrial toxicity in fetal Erythrocebus patas monkeys exposed transplacentally to zidovudine plus lamivudine.
AIDS research and human retroviruses 2004;20(1):91-100.
2003: Miriam C Poirier; Rao L Divi; Lena Al-Harthi; Ofelia A Olivero; Vi Nguyen; Brettania Walker; Alan L Landay; Vernon E Walker; Man E Charurat; William A Blattner
Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers.
Journal of acquired immune deficiency syndromes (1999) 2003;33(2):175-83.
2002: Hilde E van Gijssel; Rao L Divi; Ofelia A Olivero; Mark J Roth; Guo-Qing Wang; Sanford M Dawsey; Paul S Albert; You-Lin Qiao; Philip R Taylor; Zhi-Wei Dong; Jeffrey A Schrager; David E Kleiner; Miriam C Poirier
Semiquantitation of polycyclic aromatic hydrocarbon-DNA adducts in human esophagus by immunohistochemistry and the automated cellular imaging system.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(12):1622-9.
2002: Ofelia A Olivero; Juan J Fernandez; Brendan Antiochos; Jessica L Wagner; Marisa E St Claire; Miriam C Poirier
Transplacental genotoxicity of combined antiretroviral nucleoside analogue therapy in Erythrocebus patas monkeys.
Journal of acquired immune deficiency syndromes (1999) 2002;29(4):323-9.
2001: Ofelia A Olivero; M K Reddy; S M Pietras; Miriam C Poirier
Plasma drug levels compared with DNA incorporation of 3'-azido-3'-deoxythymidine (AZT) in adult cynomolgus (Macaca fascicularis) monkeys.
Experimental biology and medicine (Maywood, N.J.) 2001;226(5):446-9.
2001: Agueda M Tejera; DANIEL ALONSO; daniel gomez; Ofelia A Olivero
Chronic in vitro exposure to 3'-azido-2', 3'-dideoxythymidine induces senescence and apoptosis and reduces tumorigenicity of metastatic mouse mammary tumor cells.
Breast cancer research and treatment 2001;65(2):93-9.
2000: Quanxin Meng; Dale M Walker; Ofelia A Olivero; X Shi; Brendan Antiochos; Miriam C Poirier; Vernon E Walker
Zidovudine-didanosine coexposure potentiates DNA incorporation of zidovudine and mutagenesis in human cells.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12667-71.
2000: Ofelia A Olivero; Gene M Shearer; Claire Chougnet; Andrea Kovacs; R Baker; Alice Stek; M M Khoury; Miriam C Poirier
Incorporation of zidovudine into cord blood DNA of infants and peripheral blood DNA of their HIV-1-positive mothers.
Annals of the New York Academy of Sciences 2000;918():262-8.
2000: Mark J Roth; Sanford M Dawsey; G Wang; Joseph A Tangrea; B Zhou; D Luke Ratnasinghe; Karen Woodson; Ofelia A Olivero; Miriam C Poirier; Bonnie L Frye; Philip R Taylor; Ainsley Weston
Association between GSTM1*0 and squamous dysplasia of the esophagus in the high risk region of Linxian, China.
Cancer letters 2000;156(1):73-81.
2000: Aneta Bialkowska; Karol Bialkowski; Mariana Gerschenson; Bhalchandra A Diwan; A B Jones; Ofelia A Olivero; Miriam C Poirier; Lucy M Anderson; Kazimierz S Kasprzak; MA Sipowicz
Oxidative DNA damage in fetal tissues after transplacental exposure to 3'-azido-3'-deoxythymidine (AZT).
Carcinogenesis 2000;21(5):1059-62.
2000: William Slikker; Ofelia A Olivero; Patterson Tucker; Miriam C Poirier
Potential toxicities of HIV therapeutics in the developing infant.
Teratology 2000;61(5):397-8.
2000: Bhalchandra A Diwan; Ofelia A Olivero; Miriam C Poirier
Absence of structural or functional alterations in male and female reproductive organs of F1 and F2 generations derived from female mice exposed to 3'-azido-3'-deoxythymidine during pregnancy.
Toxicology letters 2000;115(1):9-15.
2000: Q Meng; T Su; Ofelia A Olivero; Miriam C Poirier; X Shi; X Ding; Vernon E Walker
Relationships between DNA incorporation, mutant frequency, and loss of heterozygosity at the TK locus in human lymphoblastoid cells exposed to 3'-azido-3'-deoxythymidine.
Toxicological sciences : an official journal of the Society of Toxicology 2000;54(2):322-9.
1999: Miriam C Poirier; Patterson Tucker; W Slikker; Ofelia A Olivero
Incorporation of 3'-azido-3'-deoxythymidine (AZT) into fetal DNA and fetal tissue distribution of drug after infusion of pregnant late-term rhesus macaques with a human-equivalent AZT dose.
Journal of acquired immune deficiency syndromes (1999) 1999;22(5):477-83.
1999: Bhalchandra A Diwan; CW Riggs; Daniel Logsdon; Diana C Haines; Ofelia A Olivero; Jerry M Rice; S H Yuspa; Miriam C Poirier; Lucy M Anderson
Multiorgan transplacental and neonatal carcinogenicity of 3'-azido-3'-deoxythymidine in mice.
Toxicology and applied pharmacology 1999;161(1):82-99.
1999: HE Sussman; Ofelia A Olivero; Quanxin Meng; S M Pietras; Miriam C Poirier; J Patrick O'Neill; Barry A Finette; Michael J Bauer; Vernon E Walker
Genotoxicity of 3'-azido-3'-deoxythymidine in the human lymphoblastoid cell line, TK6: relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT.
Mutation research 1999;429(2):249-59.
1999: Ofelia A Olivero; R Parikka; Miriam C Poirier; Kirsi Vähäkangas
3'-azido-3'-deoxythymidine (AZT) transplacental perfusion kinetics and DNA incorporation in normal human placentas perfused with AZT.
Mutation research 1999;428(1-2):41-7.
1999: Ofelia A Olivero; Gene M Shearer; Claire Chougnet; Andrea Kovacs; Alan L Landay; R Baker; Alice Stek; M M Khoury; Laurie A Proia; Harold A Kessler; Beverly E Sha; R E Tarone; Miriam C Poirier
Incorporation of zidovudine into leukocyte DNA from HIV-1-positive adults and pregnant women, and cord blood from infants exposed in utero.
AIDS (London, England) 1999;13(8):919-25.
1998: Ofelia A Olivero; daniel gomez
Correspondence re: S. M. Melana et al., Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by 3'-azido-3'-deoxythymidine. Clin. Cancer Res., 4: 693-696, 1998.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(10):2569-70.
1998: Z Zhang; Bhalchandra A Diwan; Lucy M Anderson; Daniel Logsdon; Ofelia A Olivero; Diana C Haines; Jerry M Rice; Stuart H Yuspa; Miriam C Poirier
Skin tumorigenesis and Ki-ras and Ha-ras mutations in tumors from adult mice exposed in utero to 3'-azido-2',3'-dideoxythymidine.
Molecular carcinogenesis 1998;23(1):45-51.
1998: daniel gomez; Agueda M Tejera; Ofelia A Olivero
Irreversible telomere shortening by 3'-azido-2',3'-dideoxythymidine (AZT) treatment.
Biochemical and biophysical research communications 1998;246(1):107-10.
1997: Ofelia A Olivero; Lucy M Anderson; Bhalchandra A Diwan; Diana C Haines; Steven W Harbaugh; T J Moskal; A B Jones; Jerry M Rice; CW Riggs; Daniel Logsdon; Stuart H Yuspa; Miriam C Poirier
Transplacental effects of 3'-azido-2',3'-dideoxythymidine (AZT): tumorigenicity in mice and genotoxicity in mice and monkeys.
Journal of the National Cancer Institute 1997;89(21):1602-8.
1997: Ofelia A Olivero; P K Chang; D M Lopez-Larraza; M C Semino-Mora; Miriam C Poirier
Preferential formation and decreased removal of cisplatin-DNA adducts in Chinese hamster ovary cell mitochondrial DNA as compared to nuclear DNA.
Mutation research 1997;391(1-2):79-86.
1997: A J Giurgiovich; Lucy M Anderson; A B Jones; Lee F Dove; T J Moskal; Jerry M Rice; Ofelia A Olivero; Miriam C Poirier
Transplacental cisplatin exposure induces persistent fetal mitochondrial and genomic DNA damage in patas monkeys.
Reproductive toxicology (Elmsford, N.Y.) 1997;11(1):95-100.
1997: A J Giurgiovich; Bhalchandra A Diwan; Ofelia A Olivero; Lucy M Anderson; Jerry M Rice; Miriam C Poirier
Elevated mitochondrial cisplatin-DNA adduct levels in rat tissues after transplacental cisplatin exposure.
Carcinogenesis 1997;18(1):93-6.
1995: Ofelia A Olivero; C Semino; A Kassim; D M Lopez-Larraza; Miriam C Poirier
Preferential binding of cisplatin to mitochondrial DNA of Chinese hamster ovary cells.
Mutation research 1995;346(4):221-30.
1994: Ofelia A Olivero; F A Beland; N F Fullerton; Miriam C Poirier
Vaginal epithelial DNA damage and expression of preneoplastic markers in mice during chronic dosing with tumorigenic levels of 3'-azido-2',3'-dideoxythymidine.
Cancer research 1994;54(23):6235-42.
1993: Ofelia A Olivero; Miriam C Poirier
Preferential incorporation of 3'-azido-2',3'-dideoxythymidine into telomeric DNA and Z-DNA-containing regions of Chinese hamster ovary cells.
Molecular carcinogenesis 1993;8(2):81-8.
1990: Ofelia A Olivero; C Semino; Miriam C Poirier
Localization of DNA adducts induced by N-acetoxy-N-2-acetylaminofluorene in Chinese hamster ovary cells using electron microscopy and colloidal gold.
Genes, chromosomes & cancer 1990;2(2):130-6.
1990: Ofelia A Olivero; H Huitfeldt; Miriam C Poirier
Chromosome site-specific immunohistochemical detection of DNA adducts in N-acetoxy-2-acetylaminofluorene--exposed Chinese hamster ovary cells.
Molecular carcinogenesis 1990;3(1):37-43.