FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Arthur Olson

Research Profile

Concepts & Ideas

Chemicals & Drugs

Activities & Behaviors

Phenomena

Procedures

X Ray Crystallography

Occupations

Living Beings

Co-author Network

Publications

TOP 3
Garrett M Morris; Arthur J Olson; Zoran Radić; K Barry Sharpless; Palmer Taylor; Luke G Green; Flavio Grynszpan
Automated docking with protein flexibility in the design of femtomolar "click chemistry" inhibitors of acetylcholinesterase.
Stefano Forli; Arthur J Olson
A force field with discrete displaceable waters and desolvation entropy for hydrated ligand docking.
Ying Chuan Lin; Alexander L Perryman; Arthur J Olson; Bruce E Torbett; John H Elder; C David Stout
Structural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV protease.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Arthur Olson (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Garrett M Morris; Arthur J Olson; Zoran Radić; K Barry Sharpless; Palmer Taylor; Luke G Green; Flavio Grynszpan
Automated docking with protein flexibility in the design of femtomolar "click chemistry" inhibitors of acetylcholinesterase.
Journal of chemical information and modeling 2013;53(4):898-906.
2012: Stefano Forli; Arthur J Olson
A force field with discrete displaceable waters and desolvation entropy for hydrated ligand docking.
Journal of medicinal chemistry 2012;55(2):623-38.
2011: Ying Chuan Lin; Alexander L Perryman; Arthur J Olson; Bruce E Torbett; John H Elder; C David Stout
Structural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV protease.
Acta crystallographica. Section D, Biological crystallography 2011;67(Pt 6):540-8.
2011: Graham T Johnson; Ludovic Autin; David S Goodsell; Michel F Sanner; Arthur J Olson
ePMV embeds molecular modeling into professional animation software environments.
Structure (London, England : 1993) 2011;19(3):293-303.
2010: Géza Ambrus; Landon R Whitby; Eric L Singer; Oleg Trott; Euna Choi; Arthur J Olson; Dale L Boger; Larry Gerace
Small molecule peptidomimetic inhibitors of importin α/β mediated nuclear transport.
Bioorganic & medicinal chemistry 2010;18(21):7611-20.
2010: Alex L Perryman; Stefano Forli; Garrett M Morris; Catherine Burt; Yuhui Cheng; Michael J Palmer; Kevin Whitby; J Andrew McCammon; Chris Phillips; Arthur J Olson
A dynamic model of HIV integrase inhibition and drug resistance.
Journal of molecular biology 2010;397(2):600-15.
2010: Alexander L Perryman; Qing Zhang; Holly H Soutter; Robin Rosenfeld; Duncan E McRee; Arthur J Olson; John E Elder; C David Stout
Fragment-based screen against HIV protease.
Chemical biology & drug design 2010;75(3):257-68.
2010: Oleg Trott; Arthur J Olson
AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading.
Journal of computational chemistry 2010;31(2):455-61.
2009: Garrett M Morris; Ruth Huey; William Lindstrom; Michel F Sanner; ruttinger J; David S Goodsell; Arthur J Olson
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility.
Journal of computational chemistry 2009;30(16):2785-91.
2009: Sandro Cosconati; Luciana Marinelli; Roberta Trotta; Ada Virno; Luciano Mayol; Ettore Novellino; Arthur J Olson; Antonio Randazzo
Tandem application of virtual screening and NMR experiments in the discovery of brand new DNA quadruplex groove binders.
Journal of the American Chemical Society 2009;131(45):16336-7.
2009: Qing Zhang; Helle H Petersen; Henrik Ostergaard; Wolfram Ruf; Arthur J Olson
Molecular dynamics simulations and functional characterization of the interactions of the PAR2 ectodomain with factor VIIa.
Proteins 2009;77(3):559-69.
2009: Sandro Cosconati; Luciana Marinelli; Concettina La Motta; Stefania Sartini; Federico Da Settimo; Arthur J Olson; Ettore Novellino
Pursuing aldose reductase inhibitors through in situ cross-docking and similarity-based virtual screening.
Journal of medicinal chemistry 2009;52(18):5578-81.
2009: Hao Jiang; Kristen E. Bower; Albert E. Beuscher; Bin Zhou; Andrey A Bobkov; Arthur J Olson; Peter K Vogt
Stabilizers of the Max homodimer identified in virtual ligand screening inhibit Myc function.
Molecular pharmacology 2009;76(3):491-502.
2009: J Jefferson P Perry; Rodney M Harris; davide moiani; Arthur J Olson; John A Tainer
p38alpha MAP kinase C-terminal domain binding pocket characterized by crystallographic and computational analyses.
Journal of molecular biology 2009;391(1):1-11.
2009: Qing Zhang; Michel F Sanner; Arthur J Olson
Shape complementarity of protein-protein complexes at multiple resolutions.
Proteins 2009;75(2):453-67.
2008: Sandro Cosconati; Jiyoung A Hong; Ettore Novellino; Kate S Carroll; David S Goodsell; Arthur J Olson
Structure-based virtual screening and biological evaluation of Mycobacterium tuberculosis adenosine 5'-phosphosulfate reductase inhibitors.
Journal of medicinal chemistry 2008;51(21):6627-30.
2008: Max W Chang; Richard K Belew; Kate S Carroll; Arthur J Olson; David S Goodsell
Empirical entropic contributions in computational docking: evaluation in APS reductase complexes.
Journal of computational chemistry 2008;29(11):1753-61.
2008: Fujie Tanaka; Yunfeng Hu; Jori Sutton; Lily Asawapornmongkol; Roberta Fuller; Arthur J Olson; Carlos F Barbas; Richard A Lerner
Selection of phage-displayed peptides that bind to a particular ligand-bound antibody.
Bioorganic & medicinal chemistry 2008;16(11):5926-31.
2008: Rodney Harris; Arthur J Olson; David S Goodsell
Automated prediction of ligand-binding sites in proteins.
Proteins 2008;70(4):1506-17.
2007: Arthur J Olson; Yunfeng H E Hu; Ehud Keinan
Chemical mimicry of viral capsid self-assembly.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(52):20731-6.
2007: Michael J Evans; Garrett M Morris; Jane Wu; Arthur J Olson; Erik J Sorensen; Benjamin F Cravatt
Mechanistic and structural requirements for active site labeling of phosphoglycerate mutase by spiroepoxides.
Molecular bioSystems 2007;3(7):495-506.
2007: Max W Chang; William Lindstrom; Arthur J Olson; ruttinger J
Analysis of HIV wild-type and mutant structures via in silico docking against diverse ligand libraries.
Journal of chemical information and modeling 2007;47(3):1258-62.
2007: Ruth Huey; Garrett M Morris; Arthur J Olson; David S Goodsell
A semiempirical free energy force field with charge-based desolvation.
Journal of computational chemistry 2007;28(6):1145-52.
2007: Lan Xu; Youhoon Chong; Inhwan Hwang; Anthony D'Onofrio; Kristen Amore; G Peter Beardsley; Chenglong Li; Arthur J Olson; Dale L Boger; Ian A Wilson
Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase.
The Journal of biological chemistry 2007;282(17):13033-46.
2006: Matthew Whiting; Jonathan C Tripp; Ying-Chuan Lin; William Lindstrom; Arthur J Olson; John H Elder; K Barry Sharpless; Valery V Fokin
Rapid discovery and structure-activity profiling of novel inhibitors of human immunodeficiency virus type 1 protease enabled by the copper(I)-catalyzed synthesis of 1,2,3-triazoles and their further functionalization.
Journal of medicinal chemistry 2006;49(26):7697-710.
2006: Lisa M Eubanks; Claude J Rogers; Albert E. Beuscher; George F Koob; Arthur J Olson; Tobin J Dickerson; Kim D Janda
A molecular link between the active component of marijuana and Alzheimer's disease pathology.
Molecular pharmaceutics 2006;3(6):773-7.
2006: Jessica P Rogers; Albert E. Beuscher; Marc Flajolet; Thomas McAvoy; Angus Nairn; Arthur J Olson; Paul Greengard
Discovery of protein phosphatase 2C inhibitors by virtual screening.
Journal of medicinal chemistry 2006;49(5):1658-67.
2006: Matthew Whiting; John Muldoon; Ying-Chuan Lin; Steven M Silverman; William Lindstrom; Arthur J Olson; Hartmuth C Kolb; MG Finn; K Barry Sharpless; John H Elder; Valery V Fokin
Inhibitors of HIV-1 protease by using in situ click chemistry.
Angewandte Chemie (International ed. in English) 2006;45(9):1435-9.
2005: Tobin J Dickerson; Albert E. Beuscher; Claude J Rogers; Mark Hixon; Noboru Yamamoto; Yang Xu; Arthur J Olson; Kim D Janda
Discovery of acetylcholinesterase peripheral anionic site ligands through computational refinement of a directed library.
Biochemistry 2005;44(45):14845-53.
2005: Ashraf Brik; Jerry Alexandratos; Ying-Chuan Lin; John H Elder; Arthur J Olson; Alexander Wlodawer; David S Goodsell; Chi-Huey Wong
1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors.
Chembiochem : a European journal of chemical biology 2005;6(7):1167-9.
2005: Aymeric de Parseval; Udayan Chatterji; Garrett Morris; Peiqing Sun; Arthur J Olson; John H Elder
Structural mapping of CD134 residues critical for interaction with feline immunodeficiency virus.
Nature structural & molecular biology 2005;12(1):60-6.
2004: Chenglong Li; Lan Xu; Dennis W Wolan; Ian A Wilson; Arthur J Olson
Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors.
Journal of medicinal chemistry 2004;47(27):6681-90.
2004: Lan Xu; Chenglong Li; Arthur J Olson; Ian A Wilson
Crystal structure of avian aminoimidazole-4-carboxamide ribonucleotide transformylase in complex with a novel non-folate inhibitor identified by virtual ligand screening.
The Journal of biological chemistry 2004;279(48):50555-65.
2004: Xueyong Zhu; Fujie Tanaka; Yunfeng Hu; Andreas Heine; Roberta Fuller; Guofu Zhong; Arthur J Olson; Richard A Lerner; Carlos F Barbas; Ian A Wilson
The origin of enantioselectivity in aldolase antibodies: crystal structure, site-directed mutagenesis, and computational analysis.
Journal of molecular biology 2004;343(5):1269-80.
2003: Brian V Norledge; Ramona J Petrovan; Wolfram Ruf; Arthur J Olson
The tissue factor/factor VIIa/factor Xa complex: a model built by docking and site-directed mutagenesis.
Proteins 2003;53(3):640-8.
2003: Ashraf Brik; John Muldoon; Ying-Chuan Lin; John H Elder; David S Goodsell; Arthur J Olson; Valery V Fokin; K Barry Sharpless; Chi-Huey Wong
Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors.
Chembiochem : a European journal of chemical biology 2003;4(11):1246-8.
2003: Haining Huang; Brian V Norledge; Cheng Liu; Arthur J Olson; Thomas S Edgington
Selective attenuation of the extrinsic limb of the tissue factor-driven coagulation protease cascade by occupancy of a novel peptidyl docking site on tissue factor.
Biochemistry 2003;42(36):10619-26.
2003: Robin J Rosenfeld; David S Goodsell; Rabi A Musah; Garrett M Morris; David B Goodin; Arthur J Olson
Automated docking of ligands to an artificial active site: augmenting crystallographic analysis with computer modeling.
Journal of computer-aided molecular design 2003;17(8):525-36.
2003: Ying-Chuan Lin; Zachary Q Beck; Garrett M Morris; Arthur J Olson; John H Elder
Structural basis for distinctions between substrate and inhibitor specificities for feline immunodeficiency virus and human immunodeficiency virus proteases.
Journal of virology 2003;77(12):6589-600.
2003: Yan Zhang; Joel Desharnais; Thomas H Marsilje; Chenglong Li; Michael P Hedrick; Lata T Gooljarsingh; Ali Tavassoli; Stephen J Benkovic; Arthur J Olson; Dale L Boger; Ian A Wilson
Rational design, synthesis, evaluation, and crystal structure of a potent inhibitor of human GAR Tfase: 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid.
Biochemistry 2003;42(20):6043-56.
2003: Chi Ching Mak; Ashraf Brik; Deborah L Lerner; John H Elder; Garrett M Morris; Arthur J Olson; Chi-Huey Wong
Design and synthesis of broad-based mono- and bi- cyclic inhibitors of FIV and HIV proteases.
Bioorganic & medicinal chemistry 2003;11(9):2025-40.
2002: Robin J Rosenfeld; Elsa D Garcin; Koustubh Panda; Gunilla Andersson; Anders Aberg; Alan V Wallace; Garrett M Morris; Arthur J Olson; Dennis J Stuehr; John A Tainer; Elizabeth D Getzoff
Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency.
Biochemistry 2002;41(47):13915-25.
2002: Glen B Legge; Garrett M Morris; Michel F Sanner; Yoshikazu Takada; Arthur J Olson; Flavio Grynszpan
Model of the alphaLbeta2 integrin I-domain/ICAM-1 DI interface suggests that subtle changes in loop orientation determine ligand specificity.
Proteins 2002;48(2):151-60.
2002: Daniel Stoffler; Michel F Sanner; Garrett M Morris; Arthur J Olson; David S Goodsell
Evolutionary analysis of HIV-1 protease inhibitors: Methods for design of inhibitors that evade resistance.
Proteins 2002;48(1):63-74.
2002: Fredrik Osterberg; Garrett M Morris; Michel F Sanner; Arthur J Olson; David S Goodsell
Automated docking to multiple target structures: incorporation of protein mobility and structural water heterogeneity in AutoDock.
Proteins 2002;46(1):34-40.
2001: S Zhao; Garrett M Morris; Arthur J Olson; David S Goodsell
Recognition templates for predicting adenylate-binding sites in proteins.
Journal of molecular biology 2001;314(5):1245-55.
2001: Bernd Bühler; Ying-Chuan Lin; G Morris; Arthur J Olson; Chi-Huey Wong; Douglas D Richman; John H Elder; Bruce E Torbett
Viral evolution in response to the broad-based retroviral protease inhibitor TL-3.
Journal of virology 2001;75(19):9502-8.
2001: S Zhao; David S Goodsell; Arthur J Olson
Analysis of a data set of paired uncomplexed protein structures: new metrics for side-chain flexibility and model evaluation.
Proteins 2001;43(3):271-9.
2001: R S Nunn; Tom Macke; Arthur J Olson; Mark Yeager
Transmembrane alpha-helices in the gap junction membrane channel: systematic search of packing models based on the pair potential function.
Microscopy research and technique 2001;52(3):344-51.
2000: Ying-Chuan Lin; Zachary Q Beck; T Lee; VD Le; Garrett M Morris; Arthur J Olson; Chi-Huey Wong; John H Elder
Alteration of substrate and inhibitor specificity of feline immunodeficiency virus protease.
Journal of virology 2000;74(10):4710-20.
2000: M Li; Garrett M Morris; T Lee; Gary S Laco; C H Wong; Arthur J Olson; John H Elder; Alexander Wlodawer; Alla Gustchina
Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease.
Proteins 2000;38(1):29-40.
1999: Christopher Rosin; ruttinger J; W L Walker; Garrett M Morris; Arthur J Olson; David S Goodsell
Coevolution and subsite decomposition for the design of resistance-evading HIV-1 protease inhibitors.
Journal of molecular biology 1999;287(1):77-92.
1999: Christopher Rosin; ruttinger J; Garrett M Morris; Arthur J Olson; David S Goodsell
Coevolutionary analysis of resistance-evading peptidomimetic inhibitors of HIV-1 protease.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(4):1369-74.
1999: M S Rao; Arthur J Olson
Modelling of factor Xa-inhibitor complexes: a computational flexible docking approach.
Proteins 1999;34(2):173-83.
1999: Michel F Sanner; B S Duncan; C J Carrillo; Arthur J Olson
Integrating computation and visualization for biomolecular analysis: an example using python and AVS.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 1999;():401-12.
1998: Tom Macke; B S Duncan; D S Goodsell; Arthur J Olson
Interactive modeling of supramolecular assemblies.
Journal of molecular graphics & modelling 1998;16(3):115-20, 162-3.
1998: Christopher Rosin; ruttinger J; Garrett M Morris; Arthur J Olson; David S Goodsell
Computational coevolution of antiviral drug resistance.
Artificial life 1998;4(1):41-59.
1998: Arthur J Olson; David S Goodsell
Automated docking and the search for HIV protease inhibitors.
SAR and QSAR in environmental research 1998;8(3-4):273-85.
1998: Arthur J Olson; Michael E Pique
Visualizing the future of molecular graphics.
SAR and QSAR in environmental research 1998;8(3-4):233-47.
1997: BA Reva; Alexei V Finkelstein; Michel F Sanner; Arthur J Olson; Jeffrey Skolnick
Recognition of protein structure on coarse lattices with residue-residue energy functions.
Protein engineering 1997;10(10):1123-30.
1997: BA Reva; Alexei V Finkelstein; Michel F Sanner; Arthur J Olson
Residue-residue mean-force potentials for protein structure recognition.
Protein engineering 1997;10(8):865-76.
1997: Gary S Laco; MC Fitzgerald; Garrett M Morris; Arthur J Olson; S B Kent; John H Elder
Molecular analysis of the feline immunodeficiency virus protease: generation of a novel form of the protease by autoproteolysis and construction of cleavage-resistant proteases.
Journal of virology 1997;71(7):5505-11.
1997: Michel F Sanner; Arthur J Olson
Real time surface reconstruction for moving molecular fragments.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 1997;():385-96.
1997: BA Reva; Alexei V Finkelstein; Michel F Sanner; Arthur J Olson
Accurate mean-force pairwise-residue potentials for discrimination of protein folds.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 1997;():373-84.
1996: BA Reva; Alexei V Finkelstein; DS Rykunov; Arthur J Olson
Building self-avoiding lattice models of proteins using a self-consistent field optimization.
Proteins 1996;26(1):1-8.
1996: Garrett M Morris; D S Goodsell; R Huey; Arthur J Olson
Distributed automated docking of flexible ligands to proteins: parallel applications of AutoDock 2.4.
Journal of computer-aided molecular design 1996;10(4):293-304.
1996: BA Reva; Alexei V Finkelstein; Michel F Sanner; Arthur J Olson
Adjusting potential energy functions for lattice models of chain molecules.
Proteins 1996;25(3):379-88.
1996: Michel F Sanner; Arthur J Olson; J C Spehner
Reduced surface: an efficient way to compute molecular surfaces.
Biopolymers 1996;38(3):305-20.
1996: D S Goodsell; Garrett M Morris; Arthur J Olson
Automated docking of flexible ligands: applications of AutoDock.
Journal of molecular recognition : JMR 1996;9(1):1-5.
1995: B S Duncan; T J Macke; Arthur J Olson
Biomolecular visualization using AVS.
Journal of molecular graphics 1995;13(5):271-82, 299.
1995: B S Duncan; Arthur J Olson
Texture mapping parametric molecular surfaces.
Journal of molecular graphics 1995;13(4):258-64.
1995: B S Duncan; Arthur J Olson
Approximation and visualization of large-scale motion of protein surfaces.
Journal of molecular graphics 1995;13(4):250-7.
1995: BA Reva; DS Rykunov; Arthur J Olson; Alexei V Finkelstein
Constructing lattice models of protein chains with side groups.
Journal of computational biology : a journal of computational molecular cell biology 1995;2(4):527-35.
1993: D S Goodsell; H Lauble; C David Stout; Arthur J Olson
Automated docking in crystallography: analysis of the substrates of aconitase.
Proteins 1993;17(1):1-10.
1993: D S Goodsell; Arthur J Olson
Soluble proteins: size, shape and function.
Trends in biochemical sciences 1993;18(3):65-8.
1993: B S Duncan; Arthur J Olson
Shape analysis of molecular surfaces.
Biopolymers 1993;33(2):231-8.
1993: B S Duncan; Arthur J Olson
Approximation and characterization of molecular surfaces.
Biopolymers 1993;33(2):219-29.
1992: D S Goodsell; Arthur J Olson
Molecular illustration in black and white.
Journal of molecular graphics 1992;10(4):235-40.
1992: Arthur J Olson; D S Goodsell
Visualizing biological molecules.
Scientific American 1992;267(5):76-81.
1991: Victoria A Roberts; H C Freeman; Arthur J Olson; John A Tainer; Elizabeth D Getzoff
Electrostatic orientation of the electron-transfer complex between plastocyanin and cytochrome c.
The Journal of biological chemistry 1991;266(20):13431-41.
1991: I S Mian; A R Bradwell; Arthur J Olson
Structure, function and properties of antibody binding sites.
Journal of molecular biology 1991;217(1):133-51.
1990: D S Goodsell; Arthur J Olson
Automated docking of substrates to proteins by simulated annealing.
Proteins 1990;8(3):195-202.