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Paul O'Maille

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Publications

TOP 3
Anne E Osbourn; Susan J Rosser; Paul E O'Maille; Keith Lindsey
Synthetic biology. 4th New Phytologist Workshop, Bristol, UK, June 2012.
Melissa Dokarry; Caroline Laurendon; Paul E O'Maille
Automating gene library synthesis by structure-based combinatorial protein engineering: examples from plant sesquiterpene synthases.
Steven R Garrett; Richard J Morris; Paul E O'Maille
Steady-state kinetic characterization of sesquiterpene synthases by gas chromatography-mass spectroscopy.

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All Publications

2012: Anne E Osbourn; Susan J Rosser; Paul E O'Maille; Keith Lindsey
Synthetic biology. 4th New Phytologist Workshop, Bristol, UK, June 2012.
The New phytologist 2012;196(3):671-7.
2012: Melissa Dokarry; Caroline Laurendon; Paul E O'Maille
Automating gene library synthesis by structure-based combinatorial protein engineering: examples from plant sesquiterpene synthases.
Methods in enzymology 2012;515():21-42.
2012: Steven R Garrett; Richard J Morris; Paul E O'Maille
Steady-state kinetic characterization of sesquiterpene synthases by gas chromatography-mass spectroscopy.
Methods in enzymology 2012;515():3-19.
2011: B Andes Hess; Joseph P Noel; Lidia Smentek; Paul E O'Maille
Physical constraints on sesquiterpene diversity arising from cyclization of the eudesm-5-yl carbocation.
Journal of the American Chemical Society 2011;133(32):12632-41.
2011: Nobuhiro Ikezawa; Soo-Un Kim; Don Trinh Nguyen; Paul E O'Maille; Jens Christian Göpfert; Otmar Spring; Dae-Kyun Ro
Lettuce costunolide synthase (CYP71BL2) and its homolog (CYP71BL1) from sunflower catalyze distinct regio- and stereoselective hydroxylations in sesquiterpene lactone metabolism.
The Journal of biological chemistry 2011;286(24):21601-11.
2010: Joseph P Noel; Nikki Dellas; Juan A Faraldos; Marylin Zhao; B Andes Hess; Lidia Smentek; Robert M Coates; Paul E O'Maille
Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates.
ACS chemical biology 2010;5(4):377-92.
2010: Juan A Faraldos; Paul E O'Maille; Nikki Dellas; Joseph P Noel; Robert M Coates
Bisabolyl-derived sesquiterpenes from tobacco 5-epi-aristolochene synthase-catalyzed cyclization of (2Z,6E)-farnesyl diphosphate.
Journal of the American Chemical Society 2010;132(12):4281-9.
2008: Paul E O'Maille; Arthur Malone; Nikki Dellas; B Andes Hess; Lidia Smentek; Iseult Sheehan; Bryan T Greenhagen; Joe Chappell; Gerard Manning; Joseph P Noel
Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases.
Nature chemical biology 2008;4(10):617-23.
2008: Michael B Austin; Paul E O'Maille; Joseph P Noel
Evolving biosynthetic tangos negotiate mechanistic landscapes.
Nature chemical biology 2008;4(4):217-22.
2007: Shunji Takahashi; Yun-Soo Yeo; Yuxin Zhao; Paul E O'Maille; Bryan T Greenhagen; Joseph P Noel; Robert M Coates; Joe Chappell
Functional characterization of premnaspirodiene oxygenase, a cytochrome P450 catalyzing regio- and stereo-specific hydroxylations of diverse sesquiterpene substrates.
The Journal of biological chemistry 2007;282(43):31744-54.
2007: Juan A Faraldos; Yuxin Zhao; Paul E O'Maille; Joseph P Noel; Robert M Coates
Interception of the enzymatic conversion of farnesyl diphosphate to 5-epi-aristolochene by using a fluoro substrate analogue: 1-fluorogermacrene A from (2E,6Z)-6-fluorofarnesyl diphosphate.
Chembiochem : a European journal of chemical biology 2007;8(15):1826-33.
2006: Bryan T Greenhagen; Paul E O'Maille; Joseph P Noel; Joe Chappell
Identifying and manipulating structural determinates linking catalytic specificities in terpene synthases.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(26):9826-31.
2006: Paul E O'Maille; Joe Chappell; Joseph P Noel
Biosynthetic potential of sesquiterpene synthases: alternative products of tobacco 5-epi-aristolochene synthase.
Archives of biochemistry and biophysics 2006;448(1-2):73-82.
2006: Tobias G Köllner; Paul E O'Maille; Nathalie Gatto; Wilhelm Boland; Jonathan Gershenzon; Jörg Degenhardt
Two pockets in the active site of maize sesquiterpene synthase TPS4 carry out sequential parts of the reaction scheme resulting in multiple products.
Archives of biochemistry and biophysics 2006;448(1-2):83-92.
2005: Shunji Takahashi; Yuxin Zhao; Paul E O'Maille; Bryan T Greenhagen; Joseph P Noel; Robert M Coates; Joe Chappell
Kinetic and molecular analysis of 5-epiaristolochene 1,3-dihydroxylase, a cytochrome P450 enzyme catalyzing successive hydroxylations of sesquiterpenes.
The Journal of biological chemistry 2005;280(5):3686-96.
2004: Paul E O'Maille; Joe Chappell; Joseph P Noel
A single-vial analytical and quantitative gas chromatography-mass spectrometry assay for terpene synthases.
Analytical biochemistry 2004;335(2):210-7.
2004: Paul E O'Maille; Ming-Daw Tsai; Bryan T Greenhagen; Joe Chappell; Joseph P Noel
Gene library synthesis by structure-based combinatorial protein engineering.
Methods in enzymology 2004;388():75-91.
2002: Paul E O'Maille; Marina Bakhtina; Ming-Daw Tsai
Structure-based combinatorial protein engineering (SCOPE).
Journal of molecular biology 2002;321(4):677-91.
1999: Junan Li; In-Ja L Byeon; K Ericson; Ming-Jye Poi; Paul E O'Maille; TL Selby; Ming-Daw Tsai
Tumor suppressor INK4: determination of the solution structure of p18INK4C and demonstration of the functional significance of loops in p18INK4C and p16INK4A.
Biochemistry 1999;38(10):2930-40.
1998: In-Ja L Byeon; Junan Li; K Ericson; TL Selby; A Tevelev; H J Kim; Paul E O'Maille; Ming-Daw Tsai
Tumor suppressor p16INK4A: determination of solution structure and analyses of its interaction with cyclin-dependent kinase 4.
Molecular cell 1998;1(3):421-31.