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Haruo Onda

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Hideki Kizawa; Kazunori Nishi; Yoshihiro Ishibashi; Masataka Harada; Tsuneo Asano; Yasuaki Ito; Nobuhiro Suzuki; Shuji Hinuma; Yukio Fujisawa; Haruo Onda; Osamu Nishimura; Masahiko Fujino
Production of recombinant human relaxin 3 in AtT20 cells.
Yukio Shimomura; Mioko Harada; Mika Goto; Tsukasa Sugo; Yoshio Matsumoto; Michiko Abe; Takuya Watanabe; Taiji Asami; Chieko Kitada; Masaaki Mori; Haruo Onda; Masahiko Fujino
Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8.
Yasushi Masuda; Yoshihiro Takatsu; Yasuko Terao; Satoshi Kumano; Yoshihiro Ishibashi; Masato Suenaga; Michiko Abe; Shoji Fukusumi; Takuya Watanabe; Yasushi Shintani; Takao Yamada; Shuji Hinuma; Nobuhiro Inatomi; Tetsuya Ohtaki; Haruo Onda; Masahiko Fujino
Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors.

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All Publications

2003: Hideki Kizawa; Kazunori Nishi; Yoshihiro Ishibashi; Masataka Harada; Tsuneo Asano; Yasuaki Ito; Nobuhiro Suzuki; Shuji Hinuma; Yukio Fujisawa; Haruo Onda; Osamu Nishimura; Masahiko Fujino
Production of recombinant human relaxin 3 in AtT20 cells.
Regulatory peptides 2003;113(1-3):79-84.
2002: Yukio Shimomura; Mioko Harada; Mika Goto; Tsukasa Sugo; Yoshio Matsumoto; Michiko Abe; Takuya Watanabe; Taiji Asami; Chieko Kitada; Masaaki Mori; Haruo Onda; Masahiko Fujino
Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8.
The Journal of biological chemistry 2002;277(39):35826-32.
2002: Yasushi Masuda; Yoshihiro Takatsu; Yasuko Terao; Satoshi Kumano; Yoshihiro Ishibashi; Masato Suenaga; Michiko Abe; Shoji Fukusumi; Takuya Watanabe; Yasushi Shintani; Takao Yamada; Shuji Hinuma; Nobuhiro Inatomi; Tetsuya Ohtaki; Haruo Onda; Masahiko Fujino
Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors.
Biochemical and biophysical research communications 2002;293(1):396-402.
2002: Yoshio Matsumoto; Takuya Watanabe; Yuka Adachi; Takashi Itoh; Tetsuya Ohtaki; Haruo Onda; Tsutomu Kurokawa; Osamu Nishimura; Masahiko Fujino
Galanin-like peptide stimulates food intake in the rat.
Neuroscience letters 2002;322(1):67-9.
2002: Ken Fujiwara; Sachika Adachi; Kimie Usui; Minoru Maruyama; Hirokazu Matsumoto; Tetsuya Ohtaki; Chieko Kitada; Haruo Onda; Masahiko Fujino; Kinji Inoue
Immunocytochemical localization of a galanin-like peptide (GALP) in pituicytes of the rat posterior pituitary gland.
Neuroscience letters 2002;317(2):65-8.
2002: Yukio Fujisawa; Haruo Onda; Masahiko Fujino
[Drug discovery based on the research on orphan receptor/ligand].
Nihon rinsho. Japanese journal of clinical medicine 2002;60(1):31-7.
2001: Y Hikichi; H Matsui; I Tsuji; K Nishi; T Yamada; Yasushi Shintani; Haruo Onda
LIGHT, a member of the TNF superfamily, induces morphological changes and delays proliferation in the human rhabdomyosarcoma cell line RD.
Biochemical and biophysical research communications 2001;289(3):670-7.
2001: Shoji Fukusumi; Yugo Habata; H Yoshida; N Iijima; Yuji Kawamata; Masaki Hosoya; Ryo Fujii; Shuji Hinuma; Chieko Kitada; Yasushi Shintani; Masato Suenaga; Haruo Onda; Osamu Nishimura; M Tanaka; Yasuhiko Ibata; Masahiko Fujino
Characteristics and distribution of endogenous RFamide-related peptide-1.
Biochimica et biophysica acta 2001;1540(3):221-32.
2001: A Hori; S Honda; M Asada; Tetsuya Ohtaki; K Oda; Takuya Watanabe; Yasushi Shintani; Takao Yamada; Masato Suenaga; Chieko Kitada; Haruo Onda; Tsutomu Kurokawa; Osamu Nishimura; Masahiko Fujino
Metastin suppresses the motility and growth of CHO cells transfected with its receptor.
Biochemical and biophysical research communications 2001;286(5):958-63.
2001: Hirokazu Matsumoto; Jiro Noguchi; Yoshihiro Takatsu; Yasuko Horikoshi; Satoshi Kumano; Tetsuya Ohtaki; Chieko Kitada; T Itoh; Haruo Onda; Osamu Nishimura; Masahiko Fujino
Stimulation effect of galanin-like peptide (GALP) on luteinizing hormone-releasing hormone-mediated luteinizing hormone (LH) secretion in male rats.
Endocrinology 2001;142(8):3693-6.
2001: Haruo Onda; S Ohkubo; Yasushi Shintani; Kazuhiro Ogi; K Kikuchi; Hideyuki Tanaka; K Yamamoto; I Tsuji; Yoshihiro Ishibashi; T Yamada; Chieko Kitada; N Suzuki; H Sawada; Osamu Nishimura; Masahiko Fujino
A novel secreted tumor antigen with a glycosylphosphatidylinositol-anchored structure ubiquitously expressed in human cancers.
Biochemical and biophysical research communications 2001;285(2):235-43.
2001: Tetsuya Ohtaki; Yasushi Shintani; S Honda; Hirokazu Matsumoto; A Hori; K Kanehashi; Y Terao; Satoshi Kumano; Yoshihiro Takatsu; Y Masuda; Y Ishibashi; Takuya Watanabe; M Asada; Takao Yamada; Masato Suenaga; Chieko Kitada; S Usuki; Tsutomu Kurokawa; Haruo Onda; Osamu Nishimura; Masahiko Fujino
Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor.
Nature 2001;411(6837):613-7.
2001: M Mori; Masataka Harada; Y Terao; T Sugo; T Watanabe; Y Shimomura; M Abe; Yasushi Shintani; Haruo Onda; Osamu Nishimura; Masahiko Fujino
Cloning of a novel G protein-coupled receptor, SLT, a subtype of the melanin-concentrating hormone receptor.
Biochemical and biophysical research communications 2001;283(5):1013-8.
2001: Yuji Kawamata; Yugo Habata; Shoji Fukusumi; Masaki Hosoya; Ryo Fujii; Shuji Hinuma; N Nishizawa; Chieko Kitada; Haruo Onda; Osamu Nishimura; Masahiko Fujino
Molecular properties of apelin: tissue distribution and receptor binding.
Biochimica et biophysica acta 2001;1538(2-3):162-71.
2001: Yoshihiro Takatsu; Hirokazu Matsumoto; Tetsuya Ohtaki; Satoshi Kumano; Chieko Kitada; Haruo Onda; Osamu Nishimura; Masahiko Fujino
Distribution of galanin-like peptide in the rat brain.
Endocrinology 2001;142(4):1626-34.
2001: H Inooka; Tetsuya Ohtaki; O Kitahara; T Ikegami; S Endo; Chieko Kitada; Kazuhiro Ogi; Haruo Onda; Masahiko Fujino; Masahiro Shirakawa
Conformation of a peptide ligand bound to its G-protein coupled receptor.
Nature structural biology 2001;8(2):161-5.
2000: Shuji Hinuma; Yasushi Shintani; Shoji Fukusumi; Norio Iijima; Y Matsumoto; Masaki Hosoya; Ryo Fujii; Takuya Watanabe; K Kikuchi; Y Terao; T Yano; T Yamamoto; Yuji Kawamata; Yugo Habata; M Asada; Chieko Kitada; Tsutomu Kurokawa; Haruo Onda; Osamu Nishimura; M Tanaka; Yasuhiko Ibata; Masahiko Fujino
New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals.
Nature cell biology 2000;2(10):703-8.
2000: Masaki Hosoya; T Moriya; Yuji Kawamata; S Ohkubo; Ryo Fujii; H Matsui; Yasushi Shintani; Shoji Fukusumi; Yugo Habata; Shuji Hinuma; Haruo Onda; Osamu Nishimura; Masahiko Fujino
Identification and functional characterization of a novel subtype of neuromedin U receptor.
The Journal of biological chemistry 2000;275(38):29528-32.
2000: Ryo Fujii; Masaki Hosoya; Shoji Fukusumi; Yuji Kawamata; Yugo Habata; Shuji Hinuma; Haruo Onda; Osamu Nishimura; Masahiko Fujino
Identification of neuromedin U as the cognate ligand of the orphan G protein-coupled receptor FM-3.
The Journal of biological chemistry 2000;275(28):21068-74.
2000: Masaki Hosoya; Yuji Kawamata; Shoji Fukusumi; Ryo Fujii; Yugo Habata; Shuji Hinuma; Chieko Kitada; S Honda; Tsutomu Kurokawa; Haruo Onda; Osamu Nishimura; Masahiko Fujino
Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand apelin.
The Journal of biological chemistry 2000;275(28):21061-7.
2000: Yuji Kawamata; Ryo Fujii; Shoji Fukusumi; Yugo Habata; Masaki Hosoya; Shuji Hinuma; Chieko Kitada; Haruo Onda; Osamu Nishimura; Masahiko Fujino
Analyses for susceptibility of rat anterior pituitary cells to prolactin-releasing peptide.
Endocrine 2000;12(3):215-21.
2000: Hirokazu Matsumoto; M Maruyama; Jiro Noguchi; Yasuko Horikoshi; K Fujiwara; Chieko Kitada; Shuji Hinuma; Haruo Onda; Osamu Nishimura; K Inoue; Masahiko Fujino
Stimulation of corticotropin-releasing hormone-mediated adrenocorticotropin secretion by central administration of prolactin-releasing peptide in rats.
Neuroscience letters 2000;285(3):234-8.
1999: Tetsuya Ohtaki; Satoshi Kumano; Yoshihiro Ishibashi; Kazuhiro Ogi; H Matsui; Masataka Harada; Chieko Kitada; Tsutomu Kurokawa; Haruo Onda; Masahiko Fujino
Isolation and cDNA cloning of a novel galanin-like peptide (GALP) from porcine hypothalamus.
The Journal of biological chemistry 1999;274(52):37041-5.
1999: Minoru Maruyama; Hirokazu Matsumoto; Ken Fujiwara; J Noguchi; Chieko Kitada; Shuji Hinuma; Haruo Onda; O Nishimura; Masahiko Fujino; T Higuchi; Kinji Inoue
Central administration of prolactin-releasing peptide stimulates oxytocin release in rats.
Neuroscience letters 1999;276(3):193-6.
1999: Masaaki Mori; Tsukasa Sugo; Michiko Abe; Yukio Shimomura; M Kurihara; Chieko Kitada; K Kikuchi; Yasushi Shintani; Tsutomu Kurokawa; Haruo Onda; Osamu Nishimura; Masahiko Fujino
Urotensin II is the endogenous ligand of a G-protein-coupled orphan receptor, SENR (GPR14).
Biochemical and biophysical research communications 1999;265(1):123-9.
1999: Yugo Habata; Ryo Fujii; Masaki Hosoya; Shoji Fukusumi; Yuji Kawamata; Shuji Hinuma; Chieko Kitada; N Nishizawa; S Murosaki; Tsutomu Kurokawa; Haruo Onda; Kazuhiko Tatemoto; Masahiko Fujino
Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum.
Biochimica et biophysica acta 1999;1452(1):25-35.
1999: Ryo Fujii; Shoji Fukusumi; Masaki Hosoya; Yuji Kawamata; Yugo Habata; Shuji Hinuma; M Sekiguchi; Chieko Kitada; Tsutomu Kurokawa; Osamu Nishimura; Haruo Onda; Y Sumino; Masahiko Fujino
Tissue distribution of prolactin-releasing peptide (PrRP) and its receptor.
Regulatory peptides 1999;83(1):1-10.
1999: Yukio Shimomura; Masaaki Mori; Tsukasa Sugo; Y Ishibashi; Michiko Abe; Tsutomu Kurokawa; Haruo Onda; Osamu Nishimura; Y Sumino; Masahiko Fujino
Isolation and identification of melanin-concentrating hormone as the endogenous ligand of the SLC-1 receptor.
Biochemical and biophysical research communications 1999;261(3):622-6.
1999: Hirokazu Matsumoto; Jiro Noguchi; Yasuko Horikoshi; Yuji Kawamata; Chieko Kitada; Shuji Hinuma; Haruo Onda; Osamu Nishimura; Masahiko Fujino
Stimulation of prolactin release by prolactin-releasing peptide in rats.
Biochemical and biophysical research communications 1999;259(2):321-4.
1999: Shuji Hinuma; Haruo Onda; Masahiko Fujino
The quest for novel bioactive peptides utilizing orphan seven-transmembrane-domain receptors.
Journal of molecular medicine (Berlin, Germany) 1999;77(6):495-504.
1999: Minoru Maruyama; Hirokazu Matsumoto; Ken Fujiwara; Chieko Kitada; Shuji Hinuma; Haruo Onda; Masahiko Fujino; Kinji Inoue
Immunocytochemical localization of prolactin-releasing peptide in the rat brain.
Endocrinology 1999;140(5):2326-33.
1999: Hirokazu Matsumoto; Y Murakami; Yasuko Horikoshi; Jiro Noguchi; Yugo Habata; Chieko Kitada; Shuji Hinuma; Haruo Onda; Masahiko Fujino
Distribution and characterization of immunoreactive prolactin-releasing peptide (PrRP) in rat tissue and plasma.
Biochemical and biophysical research communications 1999;257(2):264-8.
1998: Nobuo Cho; Masataka Harada; Toshihiro Imaeda; T Imada; H Matsumoto; Yoji Hayase; Satoshi Sasaki; Shuichi Furuya; Nobuhiro Suzuki; S Okubo; K Ogi; Satoshi Endo; Haruo Onda; Masahiko Fujino
Discovery of a novel, potent, and orally active nonpeptide antagonist of the human luteinizing hormone-releasing hormone (LHRH) receptor.
Journal of medicinal chemistry 1998;41(22):4190-5.
1998: Kazuhiko Tatemoto; Masaki Hosoya; Yugo Habata; Ryo Fujii; T Kakegawa; MX Zou; Yuji Kawamata; Shoji Fukusumi; Shuji Hinuma; Chieko Kitada; Tsutomu Kurokawa; Haruo Onda; Masahiko Fujino
Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor.
Biochemical and biophysical research communications 1998;251(2):471-6.
1998: Tetsuya Ohtaki; Kazuhiro Ogi; Y Masuda; Kaoru Mitsuoka; Yoshinori Fujiyoshi; Chieko Kitada; H Sawada; Haruo Onda; Masahiko Fujino
Expression, purification, and reconstitution of receptor for pituitary adenylate cyclase-activating polypeptide. large-scale purification of a functionally active G protein-coupled receptor produced in Sf9 insect cells.
The Journal of biological chemistry 1998;273(25):15464-73.
1998: Shuji Hinuma; Yugo Habata; Ryo Fujii; Yuji Kawamata; Masaki Hosoya; Shoji Fukusumi; Chieko Kitada; Y Masuo; T Asano; Hirokazu Matsumoto; M Sekiguchi; Tsutomu Kurokawa; Osamu Nishimura; Haruo Onda; Masahiko Fujino
A prolactin-releasing peptide in the brain.
Nature 1998;393(6682):272-6.
1996: Tetsuya Ohtaki; Kazuhiro Ogi; Chieko Kitada; Shuji Hinuma; Haruo Onda
Purification of recombinant human pituitary adenylate cyclase-activating polypeptide receptor expressed in Sf9 insect cells.
Annals of the New York Academy of Sciences 1996;805():590-4.
1995: Shoji Fukusumi; Kazuhiro Ogi; Haruo Onda; Shuji Hinuma
Distribution of thyrotropin-releasing hormone receptor mRNA in rat peripheral tissues.
Regulatory peptides 1995;57(2):115-21.
1995: K Okazaki; Y Itoh; Kazuhiro Ogi; S Ohkubo; Haruo Onda
Characterization of murine PACAP mRNA.
Peptides 1995;16(7):1295-9.
1994: Shuji Hinuma; Masaki Hosoya; Kazuhiro Ogi; H Tanaka; Y Nagai; Haruo Onda
Molecular cloning and functional expression of a human thyrotropin-releasing hormone (TRH) receptor gene.
Biochimica et biophysica acta 1994;1219(2):251-9.
1994: Y Miyamoto; Yugo Habata; Tetsuya Ohtaki; Y Masuda; Kazuhiro Ogi; Haruo Onda; Masahiko Fujino
Cloning and expression of a complementary DNA encoding the bovine receptor for pituitary adenylate cyclase-activating polypeptide (PACAP).
Biochimica et biophysica acta 1994;1218(3):297-307.
1994: T Kosaka; N Suzuki; Y Ishibashi; H Matsumoto; Y Itoh; S Ohkubo; Kazuhiro Ogi; Chieko Kitada; Haruo Onda; Masahiko Fujino
Biosynthesis of human endothelins in transformants expressing cDNAs for human prepro-endothelins.
Journal of biochemistry 1994;116(2):443-9.
1993: Kazuhiro Ogi; Y Miyamoto; Y Masuda; Yugo Habata; Masaki Hosoya; Tetsuya Ohtaki; Y Masuo; Haruo Onda; Masahiko Fujino
Molecular cloning and functional expression of a cDNA encoding a human pituitary adenylate cyclase activating polypeptide receptor.
Biochemical and biophysical research communications 1993;196(3):1511-21.
1993: Masaki Hosoya; Haruo Onda; Kazuhiro Ogi; Y Masuda; Y Miyamoto; Tetsuya Ohtaki; H Okazaki; A Arimura; Masahiko Fujino
Molecular cloning and functional expression of rat cDNAs encoding the receptor for pituitary adenylate cyclase activating polypeptide (PACAP).
Biochemical and biophysical research communications 1993;194(1):133-43.
1992: K Okazaki; C Kimura; T Kosaka; T Watanabe; S Ohkubo; Kazuhiro Ogi; Chieko Kitada; Haruo Onda; Masahiko Fujino
Expression of human pituitary adenylate cyclase activating polypeptide (PACAP) cDNA in CHO cells and characterization of the products.
FEBS letters 1992;298(1):49-56.
1992: Masaki Hosoya; C Kimura; Kazuhiro Ogi; S Ohkubo; Y Miyamoto; H Kugoh; M Shimizu; Haruo Onda; M Oshimura; A Arimura
Structure of the human pituitary adenylate cyclase activating polypeptide (PACAP) gene.
Biochimica et biophysica acta 1992;1129(2):199-206.
1992: S Ohkubo; C Kimura; Kazuhiro Ogi; K Okazaki; Masaki Hosoya; Haruo Onda; A Miyata; A Arimura; Masahiko Fujino
Primary structure and characterization of the precursor to human pituitary adenylate cyclase activating polypeptide.
DNA and cell biology 1992;11(1):21-30.
1991: Haruo Onda; S Ohkubo; T Kosaka; T Yasuhara; Kazuhiro Ogi; Masaki Hosoya; H Matsumoto; N Suzuki; Chieko Kitada; Y Ishibashi
Expression of endothelin-2 (ET-2) gene in a human renal adenocarcinoma cell line: purification and cDNA cloning of ET-2.
Journal of cardiovascular pharmacology 1991;17 Suppl 7():S39-43.
1990: Kazuhiro Ogi; C Kimura; Haruo Onda; A Arimura; Masahiko Fujino
Molecular cloning and characterization of cDNA for the precursor of rat pituitary adenylate cyclase activating polypeptide (PACAP).
Biochemical and biophysical research communications 1990;173(3):1271-9.
1990: Haruo Onda; S Ohkubo; Kazuhiro Ogi; T Kosaka; C Kimura; H Matsumoto; N Suzuki; Masahiko Fujino
One of the endothelin gene family, endothelin 3 gene, is expressed in the placenta.
FEBS letters 1990;261(2):327-30.
1990: S Ohkubo; Y Itoh; C Kimura; Haruo Onda; Masahiko Fujino
Nucleotide sequence of a rabbit genomic DNA encoding mature endothelin-3.
Nucleic acids research 1990;18(2):374.
1990: C Kimura; S Ohkubo; Kazuhiro Ogi; Masaki Hosoya; Y Itoh; Haruo Onda; A Miyata; L Jiang; R R Dahl; H H Stibbs
A novel peptide which stimulates adenylate cyclase: molecular cloning and characterization of the ovine and human cDNAs.
Biochemical and biophysical research communications 1990;166(1):81-9.
1989: H Matsumoto; N Suzuki; Haruo Onda; Masahiko Fujino
Abundance of endothelin-3 in rat intestine, pituitary gland and brain.
Biochemical and biophysical research communications 1989;164(1):74-80.
1989: T Watanabe; Y Itoh; Kazuhiro Ogi; C Kimura; N Suzuki; Haruo Onda
Synthesis of human endothelin-1 precursors in Escherichia coli.
FEBS letters 1989;251(1-2):257-60.
1989: Y Itoh; C Kimura; Haruo Onda; Masahiko Fujino
Canine endothelin-2: cDNA sequence for the mature peptide.
Nucleic acids research 1989;17(13):5389.
1989: T Kosaka; N Suzuki; H Matsumoto; Y Itoh; T Yasuhara; Haruo Onda; Masahiko Fujino
Synthesis of the vasoconstrictor peptide endothelin in kidney cells.
FEBS letters 1989;249(1):42-6.
1989: C Kimura; Y Itoh; S Ohkubo; Kazuhiro Ogi; Haruo Onda; Masahiko Fujino
Cloning and sequencing of a canine gene segment encoding mature endothelin.
Nucleic acids research 1989;17(8):3290.
1988: Y Itoh; M Yanagisawa; S Ohkubo; C Kimura; T Kosaka; A Inoue; N Ishida; Y Mitsui; Haruo Onda; Masahiko Fujino
Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium-derived vasoconstrictor peptide, endothelin: identity of human and porcine endothelin.
FEBS letters 1988;231(2):440-4.
1986: M Seno; Shuji Hinuma; Haruo Onda; K Igarashi
A hybrid protein between IFN-gamma and IL-2.
FEBS letters 1986;199(2):187-92.
1982: Shuji Hinuma; Haruo Onda; K Naruo; Y Ichimori; M Koyama; K Tsukamoto
Translation of interleukin 2 mRNA from human peripheral blood leukocytes in Xenopus oocytes.
Biochemical and biophysical research communications 1982;109(2):363-9.