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Tiong Ong

Research Profile

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Publications

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Wen Chun Juan; S Tiong Ong
The role of protein phosphorylation in therapy resistance and disease progression in chronic myelogenous leukemia.
Matthew R Janes; Jose J Limon; Lomon So; Jing Chen; Raymond J Lim; Melissa A Chavez; Collin Vu; Michael B Lilly; Sharmila Mallya; S Tiong Ong; Marina Konopleva; Michael B Martin; Pingda Ren; Yi Liu; Christian Rommel; David A Fruman
Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.
Min Zhang; Wuxia Fu; Sharmila Prabhu; James C Moore; Je Ko; Jung Woo Kim; Brian J Druker; Valerie Trapp; John P Fruehauf; Hermann Gram; Hung Y Fan; S Tiong Ong
Inhibition of polysome assembly enhances imatinib activity against chronic myelogenous leukemia and overcomes imatinib resistance.

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All Publications

2012: Wen Chun Juan; S Tiong Ong
The role of protein phosphorylation in therapy resistance and disease progression in chronic myelogenous leukemia.
Progress in molecular biology and translational science 2012;106():107-42.
2010: Matthew R Janes; Jose J Limon; Lomon So; Jing Chen; Raymond J Lim; Melissa A Chavez; Collin Vu; Michael B Lilly; Sharmila Mallya; S Tiong Ong; Marina Konopleva; Michael B Martin; Pingda Ren; Yi Liu; Christian Rommel; David A Fruman
Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.
Nature medicine 2010;16(2):205-13.
2008: Min Zhang; Wuxia Fu; Sharmila Prabhu; James C Moore; Je Ko; Jung Woo Kim; Brian J Druker; Valerie Trapp; John P Fruehauf; Hermann Gram; Hung Y Fan; S Tiong Ong
Inhibition of polysome assembly enhances imatinib activity against chronic myelogenous leukemia and overcomes imatinib resistance.
Molecular and cellular biology 2008;28(20):6496-509.
2007: Adrian F Arechiga; Bryan D Bell; Sabrina Leverrier; Brian M Weist; Melissa Porter; Zhengqi Wu; Yuka Kanno; Stephanie J Ramos; S Tiong Ong; Richard Siegel; Craig M Walsh
A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5291-300.
2007: S Prabhu; D Saadat; M Zhang; L Halbur; John P Fruehauf; S Tiong Ong
A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation.
Oncogene 2007;26(8):1188-200.
2003: Chi Ly; Adrian F Arechiga; Junia V Melo; Craig M Walsh; S Tiong Ong
Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin.
Cancer research 2003;63(18):5716-22.