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Brian O'Nuallain

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  • Brian O'Nuallain; Igor Klyubin; Jessica M Mc Donald; James S Foster; Alfred Welzel; Andrew Barry; Richard K Dykoski; James P Cleary; Martijn F B G Gebbink; Michael J Rowan; et al.
    A monoclonal antibody against synthetic Aβ dimer assemblies neutralizes brain-derived synaptic plasticity-disrupting Aβ.
  • Brian O'Nuallain; Darragh B Freir; Andrew J Nicoll; Emmanuel Risse; Neil Ferguson; Caroline E Herron; John Collinge; Dominic M Walsh
    Amyloid beta-protein dimers rapidly form stable synaptotoxic protofibrils.
  • Brian O'Nuallain; Angela D Williams; Helen P McWilliams-Koeppen; Luis Acero; Alfred Weber; Hartmut Ehrlich; Hans P Schwarz; Alan Solomon
    Anti-amyloidogenic activity of IgGs contained in normal plasma.
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All Publications

  • 2011: Brian O'Nuallain; Igor Klyubin; Jessica M Mc Donald; James S Foster; Alfred Welzel; Andrew Barry; Richard K Dykoski; James P Cleary; Martijn F B G Gebbink; Michael J Rowan; et al.
    A monoclonal antibody against synthetic Aβ dimer assemblies neutralizes brain-derived synaptic plasticity-disrupting Aβ.
    Journal of neurochemistry 2011;119(1):189-201.
  • 2010: Brian O'Nuallain; Darragh B Freir; Andrew J Nicoll; Emmanuel Risse; Neil Ferguson; Caroline E Herron; John Collinge; Dominic M Walsh
    Amyloid beta-protein dimers rapidly form stable synaptotoxic protofibrils.
    The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(43):14411-9.
  • 2010: Brian O'Nuallain; Angela D Williams; Helen P McWilliams-Koeppen; Luis Acero; Alfred Weber; Hartmut Ehrlich; Hans P Schwarz; Alan Solomon
    Anti-amyloidogenic activity of IgGs contained in normal plasma.
    Journal of clinical immunology 2010;30 Suppl 1():S37-42.
  • 2010: Sharad P Adekar; Igor Klyubin; Sally Macy; Michael J Rowan; Alan Solomon; Scott K Dessain; Brian O'Nuallain
    Inherent anti-amyloidogenic activity of human immunoglobulin gamma heavy chains.
    The Journal of biological chemistry 2010;285(2):1066-74.
  • 2008: Brian O'Nuallain; Luis Acero; Angela D Williams; Helen P McWilliams Koeppen; Alfred Weber; Hans P Schwarz; Jonathan S Wall; Deborah T Weiss; Alan Solomon
    Human plasma contains cross-reactive Abeta conformer-specific IgG antibodies.
    Biochemistry 2008;47(47):12254-6.
  • 2007: Brian O'Nuallain; Amy Allen; Demet Ataman; Deborah T Weiss; Alan Solomon; Jonathan S Wall
    Phage display and peptide mapping of an immunoglobulin light chain fibril-related conformational epitope.
    Biochemistry 2007;46(45):13049-58.
  • 2007: Brian O'Nuallain; Amy Allen; Stephen J Kennel; Deborah T Weiss; Alan Solomon; Jonathan S Wall
    Localization of a conformational epitope common to non-native and fibrillar immunoglobulin light chains.
    Biochemistry 2007;46(5):1240-7.
  • 2006: Brian O'Nuallain; Rudi Hrncic; Jonathan S Wall; Deborah T Weiss; Alan Solomon
    Diagnostic and therapeutic potential of amyloid-reactive IgG antibodies contained in human sera.
    Journal of immunology (Baltimore, Md. : 1950) 2006;176(11):7071-8.
  • 2006: Brian O'Nuallain; Ashwani K Thakur; Angela D Williams; Anusri M Bhattacharyya; Songming Chen; Geetha Thiagarajan; Ronald Wetzel
    Kinetics and thermodynamics of amyloid assembly using a high-performance liquid chromatography-based sedimentation assay.
    Methods in enzymology 2006;413():34-74.
  • 2005: Brian O'Nuallain; Shankaramma Shivaprasad; Indu Kheterpal; Ronald Wetzel
    Thermodynamics of A beta(1-40) amyloid fibril elongation.
    Biochemistry 2005;44(38):12709-18.
  • 2005: Jonathan S Wall; Stephen J Kennel; Michael J Paulus; Shaun Gleason; Jens Gregor; Justin Baba; Maria Schell; Tina Richey; Brian O'Nuallain; Robert Donnell; et al.
    Quantitative high-resolution microradiographic imaging of amyloid deposits in a novel murine model of AA amyloidosis.
    Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2005;12(3):149-56.
  • 2004: Brian O'Nuallain; Angela D Williams; Per Westermark; Ronald Wetzel
    Seeding specificity in amyloid growth induced by heterologous fibrils.
    The Journal of biological chemistry 2004;279(17):17490-9.
  • 2002: Songming Chen; Valerie Berthelier; J Bradley Hamilton; Brian O'Nuallain; Ronald Wetzel
    Amyloid-like features of polyglutamine aggregates and their assembly kinetics.
    Biochemistry 2002;41(23):7391-9.
  • 2002: Brian O'Nuallain; Ronald Wetzel
    Conformational Abs recognizing a generic amyloid fibril epitope.
    Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1485-90.
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