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Akira Ooshima

Research Profile

Anatomy

Chemicals & Drugs

Physiology

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Intraocular Lenses

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Eunjin Bae; Suntaek Hong; Seong-Jin Kim; Fang Liu; Akira Ooshima
Smad3 linker phosphorylation attenuates Smad3 transcriptional activity and TGF-β1/Smad3-induced epithelial-mesenchymal transition in renal epithelial cells.
Jonine D Figueroa; Kathleen C Flanders; Montserrat Garcia-Closas; William F Anderson; Xiaohong Rose Yang; Rayna K Matsuno; Máire A Duggan; Ruth M Pfeiffer; Akira Ooshima; Robert Cornelison; Gretchen L Gierach; Louise A Brinton; Jolanta Lissowska; Beata Peplonska; Lalage M Wakefield; Mark E Sherman
Expression of TGF-beta signaling factors in invasive breast cancers: relationships with age at diagnosis and tumor characteristics.
Mitsutaka Kadota; Misako Sato; Beverly Duncan; Akira Ooshima; Howard H Yang; Natacha Diaz-Meyer; Sheryl Gere; Shun-Ichiro Kageyama; Junya Fukuoka; Takuya Nagata; Kazuhiro Tsukada; Barbara K Dunn; Lalage M Wakefield; Maxwell P Lee
Identification of novel gene amplifications in breast cancer and coexistence of gene amplification with an activating mutation of PIK3CA.

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All Publications

2012: Eunjin Bae; Suntaek Hong; Seong-Jin Kim; Fang Liu; Akira Ooshima
Smad3 linker phosphorylation attenuates Smad3 transcriptional activity and TGF-β1/Smad3-induced epithelial-mesenchymal transition in renal epithelial cells.
Biochemical and biophysical research communications 2012;427(3):593-9.
2010: Jonine D Figueroa; Kathleen C Flanders; Montserrat Garcia-Closas; William F Anderson; Xiaohong Rose Yang; Rayna K Matsuno; Máire A Duggan; Ruth M Pfeiffer; Akira Ooshima; Robert Cornelison; Gretchen L Gierach; Louise A Brinton; Jolanta Lissowska; Beata Peplonska; Lalage M Wakefield; Mark E Sherman
Expression of TGF-beta signaling factors in invasive breast cancers: relationships with age at diagnosis and tumor characteristics.
Breast cancer research and treatment 2010;121(3):727-35.
2009: Mitsutaka Kadota; Misako Sato; Beverly Duncan; Akira Ooshima; Howard H Yang; Natacha Diaz-Meyer; Sheryl Gere; Shun-Ichiro Kageyama; Junya Fukuoka; Takuya Nagata; Kazuhiro Tsukada; Barbara K Dunn; Lalage M Wakefield; Maxwell P Lee
Identification of novel gene amplifications in breast cancer and coexistence of gene amplification with an activating mutation of PIK3CA.
Cancer research 2009;69(18):7357-65.
2007: Hiroki Suemoto; Yasuteru Muragaki; Katsuhiro Nishioka; Misako Sato; Akira Ooshima; Shunji Itoh; Ikuji Hatamura; Michitaka Ozaki; Attila Braun; Erika Elisabet Gustafsson; Reinhard Fässler
Trps1 regulates proliferation and apoptosis of chondrocytes through Stat3 signaling.
Developmental biology 2007;312(2):572-81.
2007: Binwu Tang; Naomi Yoo; Mary Vu; Mizuko Mamura; Jeong-Seok Nam; Akira Ooshima; Zhijun Du; Pierre-Yves Desprez; Miriam R Anver; Aleksandra M Michalowska; Joanna Shih; W Tony Parks; Lalage M Wakefield
Transforming growth factor-beta can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model.
Cancer research 2007;67(18):8643-52.
2007: Masao Fujiwara; Hiroki Suemoto; Yasuteru Muragaki; Akira Ooshima
Fas-mediated upregulation of vascular endothelial growth factor and monocyte chemoattractant protein-1 expression in cultured dermal fibroblasts: role in the inflammatory response.
The Journal of dermatology 2007;34(2):99-109.
2007: Masaaki Iwahashi; Yasuteru Muragaki; Akira Ooshima; Naohiko Umesaki
Increased type III and V collagen expression in human corpora lutea in early pregnancy.
Fertility and sterility 2007;87(1):178-81.
2006: Osamu Yamanaka; Shizuya Saika; Kazuo Ikeda; Ken-Ichi Miyazaki; Yoshitaka Ohnishi; Akira Ooshima
Interleukin-7 modulates extracellular matrix production and TGF-beta signaling in cultured human subconjunctival fibroblasts.
Current eye research 2006;31(6):491-9.
2006: Shizuya Saika; Kazuo Ikeda; Osamu Yamanaka; Kathleen C Flanders; Yuka Okada; Takeshi Miyamoto; Ai Kitano; Akira Ooshima; Yuji Nakajima; Yoshitaka Ohnishi; Winston W-Y Kao
Loss of tumor necrosis factor alpha potentiates transforming growth factor beta-mediated pathogenic tissue response during wound healing.
The American journal of pathology 2006;168(6):1848-60.
2006: Satoru Ozawa; Kazuhisa Uchiyama; Mikihito Nakamori; Kentaro Ueda; Makoto Iwahashi; Hikaru Ueno; Yasuteru Muragaki; Akira Ooshima; Hiroki Yamaue
Combination gene therapy of HGF and truncated type II TGF-beta receptor for rat liver cirrhosis after partial hepatectomy.
Surgery 2006;139(4):563-73.
2006: Masaaki Iwahashi; Yasuteru Muragaki; Akira Ooshima; Naohiko Umesaki
Immunohistochemical analysis of collagen expression in human corpora lutea during the menstrual cycle and early pregnancy.
Fertility and sterility 2006;85 Suppl 1():1093-6.
2006: Masahide Mizobuchi; Hiroaki Ogata; Ikuji Hatamura; Fumihiko Koiwa; Fumie Saji; Kazuhiro Shiizaki; Shigeo Negi; Eriko Kinugasa; Akira Ooshima; Shozo Koshikawa; Tadao Akizawa
Up-regulation of Cbfa1 and Pit-1 in calcified artery of uraemic rats with severe hyperphosphataemia and secondary hyperparathyroidism.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(4):911-6.
2006: Anita B Roberts; Fang Tian; Stacey DaCosta Byfield; Christina Stuelten; Akira Ooshima; Shizuya Saika; Kathleen C Flanders
Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis.
Cytokine & growth factor reviews 2006;17(1-2):19-27.
2006: Osamu Yamanaka; Kazuo Ikeda; Shizuya Saika; Ken-ichi Miyazaki; Akira Ooshima; Yoshitaka Ohnishi
Gene transfer of Smad7 modulates injury-induced conjunctival wound healing in mice.
Molecular vision 2006;12():841-51.
2006: Kumi Shirai; Shizuya Saika; Takeshi Tanaka; Yuka Okada; Kathleen C Flanders; Akira Ooshima; Yoshitaka Ohnishi
A new model of anterior subcapsular cataract: involvement of TGFbeta/Smad signaling.
Molecular vision 2006;12():681-91.
2006: Shizuya Saika; Kazuo Ikeda; Osamu Yamanaka; Kathleen C Flanders; Yoshitaka Ohnishi; Yuji Nakajima; Yasuteru Muragaki; Akira Ooshima
Adenoviral gene transfer of BMP-7, Id2, or Id3 suppresses injury-induced epithelial-to-mesenchymal transition of lens epithelium in mice.
American journal of physiology. Cell physiology 2006;290(1):C282-9.
2005: Masao Fujiwara; Yasuteru Muragaki; Akira Ooshima
Upregulation of transforming growth factor-beta1 and vascular endothelial growth factor in cultured keloid fibroblasts: relevance to angiogenic activity.
Archives of dermatological research 2005;297(4):161-9.
2005: Masao Fujiwara; Yasuteru Muragaki; Akira Ooshima
Keloid-derived fibroblasts show increased secretion of factors involved in collagen turnover and depend on matrix metalloproteinase for migration.
The British journal of dermatology 2005;153(2):295-300.
2005: Shizuya Saika; Osamu Yamanaka; Kazuo Ikeda; Shokei Kim-Mitsuyama; Kathleen C Flanders; Jiyun Yoo; Anita B Roberts; Iku Nishikawa-Ishida; Yoshitaka Ohnishi; Yasuteru Muragaki; Akira Ooshima
Inhibition of p38MAP kinase suppresses fibrotic reaction of retinal pigment epithelial cells.
Laboratory investigation; a journal of technical methods and pathology 2005;85(7):838-50.
2005: Shizuya Saika; Kazuo Ikeda; Osamu Yamanaka; Takeshi Miyamoto; Yoshitaka Ohnishi; Misako Sato; Yasuteru Muragaki; Akira Ooshima; Yuji Nakajima; Winston W-Y Kao; Kathleen C Flanders; Anita B Roberts
Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali.
The American journal of pathology 2005;166(5):1405-18.
2005: Shizuya Saika; Takeshi Miyamoto; Osamu Yamanaka; Tadashi Kato; Yoshitaka Ohnishi; Kathleen C Flanders; Kazuo Ikeda; Yuji Nakajima; Winston W-Y Kao; Misako Sato; Yasuteru Muragaki; Akira Ooshima
Therapeutic effect of topical administration of SN50, an inhibitor of nuclear factor-kappaB, in treatment of corneal alkali burns in mice.
The American journal of pathology 2005;166(5):1393-403.
2005: Shizuya Saika; Kazuo Ikeda; Osamu Yamanaka; Kathleen C Flanders; Yuji Nakajima; Takeshi Miyamoto; Yoshitaka Ohnishi; Winston W-Y Kao; Yasuteru Muragaki; Akira Ooshima
Therapeutic effects of adenoviral gene transfer of bone morphogenic protein-7 on a corneal alkali injury model in mice.
Laboratory investigation; a journal of technical methods and pathology 2005;85(4):474-86.
2005: Kazuhiro Shiizaki; Shigeo Negi; Ikuji Hatamura; Toshifumi Sakaguchi; Fumie Saji; Ken Kunimoto; Masahide Mizobuchi; Ikuo Imazeki; Akira Ooshima; Tadao Akizawa
Biochemical and cellular effects of direct maxacalcitol injection into parathyroid gland in uremic rats.
Journal of the American Society of Nephrology : JASN 2005;16(1):97-108.
2004: Shizuya Saika; Satoko Kono-Saika; Takeshi Tanaka; Osamu Yamanaka; Yoshitaka Ohnishi; Misako Sato; Yasuteru Muragaki; Akira Ooshima; Jiyun Yoo; Kathleen C Flanders; Anita B Roberts
Smad3 is required for dedifferentiation of retinal pigment epithelium following retinal detachment in mice.
Laboratory investigation; a journal of technical methods and pathology 2004;84(10):1245-58.
2004: Shizuya Saika; Kazuo Ikeda; Osamu Yamanaka; Misako Sato; Yasuteru Muragaki; Yoshitaka Ohnishi; Akira Ooshima; Yuji Nakajima; Kazuhiko Namikawa; Hiroshi Kiyama; Kathleen C Flanders; Anita B Roberts
Transient adenoviral gene transfer of Smad7 prevents injury-induced epithelial-mesenchymal transition of lens epithelium in mice.
Laboratory investigation; a journal of technical methods and pathology 2004;84(10):1259-70.
2004: Shizuya Saika; Yasuteru Muragaki; Yuka Okada; Takeshi Miyamoto; Yoshitaka Ohnishi; Akira Ooshima; Winston W-Y Kao
Sonic hedgehog expression and role in healing corneal epithelium.
Investigative ophthalmology & visual science 2004;45(8):2577-85.
2004: Takeshi Tanaka; Shizuya Saika; Yoshitaka Ohnishi; Akira Ooshima; John W McAvoy; Chia-Yang Liu; Mohamad Azhar; Thomas Doetschman; Winston W-Y Kao
Fibroblast growth factor 2: roles of regulation of lens cell proliferation and epithelial-mesenchymal transition in response to injury.
Molecular vision 2004;10():462-7.
2004: Shizuya Saika; Yuka Okada; Takeshi Miyamoto; Osamu Yamanaka; Yoshitaka Ohnishi; Akio Yamanaka; Akira Ooshima
Protein expression pattern of collagen type XV in mouse cornea.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2004;242(5):432-6.
2004: Shizuya Saika; Satoko Kono-Saika; Yoshitaka Ohnishi; Misako Sato; Yasuteru Muragaki; Akira Ooshima; Kathleen C Flanders; Jiyun Yoo; Mario A Anzano; Chia-Yang Liu; Winston W-Y Kao; Anita B Roberts
Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury.
The American journal of pathology 2004;164(2):651-63.
2004: Shizuya Saika; Yuka Okada; Takeshi Miyamoto; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima; Chia-Yang Liu; Daniel Weng; Winston W-Y Kao
Role of p38 MAP kinase in regulation of cell migration and proliferation in healing corneal epithelium.
Investigative ophthalmology & visual science 2004;45(1):100-9.
2003: Misako Sato; Yasuteru Muragaki; Shizuya Saika; Anita B Roberts; Akira Ooshima
Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction.
The Journal of clinical investigation 2003;112(10):1486-94.
2003: Kazuhiro Shiizaki; Ikuji Hatamura; Shigeo Negi; Nobuhiko Narukawa; Masahide Mizobuchi; Toshifumi Sakaguchi; Akira Ooshima; Tadao Akizawa
Percutaneous maxacalcitol injection therapy regresses hyperplasia of parathyroid and induces apoptosis in uremia.
Kidney international 2003;64(3):992-1003.
2003: Masaaki Iwahashi; Yasuteru Muragaki; Akira Ooshima; Naohiko Umesaki
Decreased type I collagen expression in human uterine cervix during pregnancy.
The Journal of clinical endocrinology and metabolism 2003;88(5):2231-5.
2003: Shizuya Saika; Takeshi Miyamoto; Sai-ichi Tanaka; Takeshi Tanaka; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima; Toshiyuki Ishiwata; Goro Asano; Tai-Ichiro Chikama; Atsushi Shiraishi; Chia-Yang Liu; Candace W-C Kao; Winston W-Y Kao
Response of lens epithelial cells to injury: role of lumican in epithelial-mesenchymal transition.
Investigative ophthalmology & visual science 2003;44(5):2094-102.
2003: Shizuya Saika; Takeshi Miyamoto; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima
Osteopontin: a component of matrix in capsular opacification and subcapsular cataract.
Investigative ophthalmology & visual science 2003;44(4):1622-8.
2003: Osamu Yamanaka; Shizuya Saika; Yuka Okada; Akira Ooshima; Yoshitaka Ohnishi
Effects of interferon-gamma on human subconjunctival fibroblasts in the presence of TGFbeta1: reversal of TGFbeta-stimulated collagen production.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2003;241(2):116-24.
2002: Shizuya Saika; Takeshi Miyamoto; Iku Ishida; Kumi Shirai; Yoshitaka Ohnishi; Akira Ooshima; J W McAvoy
TGFbeta-Smad signalling in postoperative human lens epithelial cells.
The British journal of ophthalmology 2002;86(12):1428-33.
2002: Shizuya Saika; Takeshi Miyamoto; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima
Lens epithelial cell death after cataract surgery.
Journal of cataract and refractive surgery 2002;28(8):1452-6.
2002: Sai-ichi Tanaka; Shizuya Saika; Shunsaku Ohmi; Takeshi Miyamoto; Iku Ishida; Yuka Okada; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima
Cellular fibronectin, but not collagens, disappears in the central posterior capsules during healing after lens extraction and IOL implantation in rabbits.
Japanese journal of ophthalmology 2002;46(2):147-52.
2002: Shizuya Saika; Yoshitaka Ohnishi; Akira Ooshima; Chia-Yang Liu; Winston W-Y Kao
Epithelial repair: roles of extracellular matrix.
Cornea 2002;21(2 Suppl 1):S23-9.
2002: Shizuya Saika; Takeshi Miyamoto; Takeshi Tanaka; Yoshitaka Ohnishi; Akira Ooshima; Wataru Kimura
Histopathology of anterior lens capsules in vitrectomized eyes with tamponade by silicone oil.
Journal of cataract and refractive surgery 2002;28(2):376-8.
2001: Shizuya Saika; Takeshi Miyamoto; Takeshi Tanaka; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima
Collagens XII and XIV (FACITs) in capsular opacification and in cultured lens epithelial cells.
Current eye research 2001;23(6):463-8.
2001: Shizuya Saika; Takeshi Miyamoto; Takeshi Tanaka; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima
Latent TGFbeta binding protein-1 and fibrillin-1 in human capsular opacification and in cultured lens epithelial cells.
The British journal of ophthalmology 2001;85(11):1362-6.
2001: Shizuya Saika; Takeshi Miyamoto; Iku Ishida; Yuka Okada; Yoshitaka Ohnishi; Akira Ooshima
Lens epithelial cell regeneration of a capsule-like structure during postoperative healing in rabbits.
Journal of cataract and refractive surgery 2001;27(7):1076-8.
2001: Masaaki Iwahashi; Yasuteru Muragaki; Akira Ooshima; R Nakano
Overexpression of type IV collagen in chorionic villi in hydatidiform mole.
The Journal of clinical endocrinology and metabolism 2001;86(6):2649-52.
2001: Shizuya Saika; Osamu Yamanaka; Y Baba; Yoshiji Kawashima; Kumi Shirai; Takeshi Miyamoto; Yuka Okada; Yoshitaka Ohnishi; Akira Ooshima
Accumulation of latent transforming growth factor-beta binding protein-1 and TGF beta 1 in extracellular matrix of filtering bleb and of cultured human subconjunctival fibroblasts.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2001;239(3):234-41.
2000: Shizuya Saika; A Minamide; Takeshi Tanaka; Takeshi Miyamoto; Yuka Okada; Yoshiji Kawashima; Yoshitaka Ohnishi; Akira Ooshima; Winston W-Y Kao
Expression of involucrin by ocular surface epithelia of patients with benign and malignant disorders.
Current eye research 2000;21(5):877-85.
2000: Shizuya Saika; Takeshi Miyamoto; Yoshiji Kawashima; K Jinza; Yuka Okada; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima
Alterations in ultrastructure and c-met expression in a case of ocular epithelial dysplasia following topical mitomycin C treatment.
Japanese journal of ophthalmology 2000;44(6):639-42.
2000: Masaaki Iwahashi; Yasuteru Muragaki; Akira Ooshima; R Nakano
Type VI collagen expression during growth of human ovarian follicles.
Fertility and sterility 2000;74(2):343-7.
2000: Shizuya Saika; Takeshi Miyamoto; Yuka Okada; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima
Transforming growth factor-beta isoform proteins in cell and matrix deposits on intraocular lenses.
Journal of cataract and refractive surgery 2000;26(5):709-15.
2000: Shizuya Saika; Yuka Okada; Kumi Shirai; Yoshiji Kawashima; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima
Immunolocalization of c-Fos and c-Jun in rat ocular surface epithelium.
Ophthalmic research 2000;32(1):9-12.
1999: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Yuka Okada; T Katoh; K Shirai; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima; Winston W-Y Kao
Immunolocalization of transcription factor AP1 in human ocular surface epithelia.
Current eye research 1999;18(6):477-89.
1999: Shizuya Saika; Yoshiji Kawashima; Yuka Okada; K Ohkawa; Osamu Yamanaka; T Katoh; Yoshitaka Ohnishi; Akira Ooshima; Winston W-Y Kao
Immunohistochemical and ultrastructural analysis of dysplastic epithelium of human ocular surface: basement membrane and intermediate filament.
Cornea 1999;18(3):343-52.
1998: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Yuka Okada; Sai-ichi Tanaka; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Pathological findings in lens capsule and silicone intraocular lens extracted from eye with chronic infectious endophthalmitis.
Japanese journal of ophthalmology 1998;42(6):456-60.
1998: Shizuya Saika; M Shimezaki; Kiyomi Ohkawa; Yuka Okada; Akihiko Tawara; Yoshitaka Ohnishi; Akira Ooshima; M Kimura; N Kurumatani; H Naka; T Awata; Winston W-Y Kao
Ultrastructural examination of corneal epithelium of spontaneously obese, hyperglycemic rats.
Current eye research 1998;17(11):1049-57.
1998: Shizuya Saika; Takeshi Miyamoto; Akio Yamanaka; Yoshiji Kawashima; Yuka Okada; Sai-ichi Tanaka; Osamu Yamanaka; Shunsaku Ohmi; Yoshitaka Ohnishi; Akira Ooshima
Immunohistochemical evaluation of cellular deposits on posterior chamber intraocular lenses.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1998;236(10):758-65.
1998: Shizuya Saika; Takeshi Miyamoto; M Kimura; Shunsaku Ohmi; K Ohkawa; Yoshiji Kawashima; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Degenerated lens epithelial cells in rabbit and human eyes after intraocular lens implantation.
Journal of cataract and refractive surgery 1998;24(10):1396-8.
1998: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Yuka Okada; Sai-ichi Tanaka; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Immunohistochemical identification of proteoglycan types in fibrotic human capsules with intraocular lens implants.
Japanese journal of ophthalmology 1998;42(5):368-72.
1998: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Yuka Okada; Sai-ichi Tanaka; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Immunolocalization of hyaluronan and CD44 in quiescent and proliferating human lens epithelial cells.
Journal of cataract and refractive surgery 1998;24(9):1266-70.
1998: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Sai-ichi Tanaka; Yuka Okada; Osamu Yamanaka; T Katoh; Yoshitaka Ohnishi; Shunsaku Ohmi; Akira Ooshima; Akio Yamanaka
Immunolocalization of prolyl 4-hydroxylase in rabbit lens epithelial cells.
Journal of cataract and refractive surgery 1998;24(9):1261-5.
1998: Shizuya Saika; Osamu Yamanaka; Yoshiji Kawashima; Kiyomi Ohkawa; Yoshitaka Ohnishi; Akira Ooshima; M Kimura; Y Nakano; Winston W-Y Kao
OPC-15161 suppresses the proliferation of Tenon's capsule fibroblasts and the production of type I collagen and fibronectin stimulated by TGF-beta1 in vitro.
Current eye research 1998;17(9):933-40.
1998: Q Li; Yasuteru Muragaki; Ikuji Hatamura; H Ueno; Akira Ooshima
Stretch-induced collagen synthesis in cultured smooth muscle cells from rabbit aortic media and a possible involvement of angiotensin II and transforming growth factor-beta.
Journal of vascular research 1998;35(2):93-103.
1998: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Yuka Okada; Sai-ichi Tanaka; Shunsaku Ohmi; A Minamide; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Immunolocalization of prolyl 4-hydroxylase subunits, alpha-smooth muscle actin, and extracellular matrix components in human lens capsules with lens implants.
Experimental eye research 1998;66(3):283-94.
1998: Shizuya Saika; Yoshiji Kawashima; Yuka Okada; Sai-ichi Tanaka; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima
Recombinant TIMP-1 and -2 enhance the proliferation of rabbit corneal epithelial cells in vitro and the spreading of rabbit corneal epithelium in situ.
Current eye research 1998;17(1):47-52.
1997: Shizuya Saika; Shunsaku Ohmi; Sai-ichi Tanaka; Takeshi Miyamoto; Yoshiji Kawashima; Yoshitaka Ohnishi; R Kanagawa; Akio Yamanaka; Akira Ooshima
Cell proliferation on the outer anterior capsule surface after extracapsular lens extraction in rabbits.
Journal of cataract and refractive surgery 1997;23(10):1528-31.
1997: Shizuya Saika; Shunsaku Ohmi; Akira Ooshima; M Kimura; Sai-ichi Tanaka; Yuka Okada; Yoshitaka Ohnishi; Akio Yamanaka
Deposition of extracellular matrix on silicone intraocular lens implants in rabbits.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1997;235(8):517-22.
1997: Shizuya Saika; Shunsaku Ohmi; Sai-ichi Tanaka; Yoshitaka Ohnishi; Akio Yamanaka; Akira Ooshima
Light and scanning electron microscopy of rabbit lens capsules with intraocular lenses.
Journal of cataract and refractive surgery 1997;23(5):787-94.
1997: Shizuya Saika; Sai-ichi Tanaka; Shunsaku Ohmi; A Minamide; Yoshitaka Ohnishi; Akio Yamanaka; Akira Ooshima; M Kimura
Deposition of extracellular matrix on intraocular lenses in rabbits: an immunohistochemical and transmission electron microscopic study.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1997;235(4):241-7.
1997: Shizuya Saika; Akira Ooshima; Osamu Yamanaka; M Kimura; Yuka Okada; O Tonoe; S Tanaka; Yoshitaka Ohnishi
In vitro effects of doxorubicin and mitomycin C on human Tenon's capsule fibroblasts.
Ophthalmic research 1997;29(2):91-102.
1996: Shizuya Saika; Shunsaku Ohmi; Akira Ooshima; M Kimura; K Ohkawa; Yuka Okada; Sai-ichi Tanaka; Yoshitaka Ohnishi; Akio Yamanaka
Collagen synthesis in lens epithelial cells on capsules containing intraocular lens implants in rabbits: immunolocalization of prolyl 4-hydroxylase.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1996;234(12):755-60.
1996: Shizuya Saika; Shunsaku Ohmi; M Kimura; Yuka Okada; Sai-ichi Tanaka; Yoshitaka Ohnishi; Akio Yamanaka; Akira Ooshima
[Electron microscopic observations on the posterior lens capsule after implantation of a silicone intraocular lens in rabbits].
Nippon Ganka Gakkai zasshi 1996;100(9):687-91.
1996: Shizuya Saika; Akira Ooshima; Osamu Yamanaka; Yuka Okada; Sai-ichi Tanaka; Yoshitaka Ohnishi
Effect of fibrostatin C, an inhibitor of prolyl 4-hydroxylase, on collagen secretion by human Tenon's capsule fibroblasts in vitro.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1996;234 Suppl 1():S214-22.
1996: Shizuya Saika; Akira Ooshima; Osamu Yamanaka; O Tonoe; Yuka Okada; Yoshitaka Ohnishi; M Kimura
Immunolocalization of prolyl 4-hydroxylase in fibroblasts cultured from Tenon's capsule of humans.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1996;234(4):251-7.
1996: Shizuya Saika; Shunsaku Ohmi; R Kanagawa; Sai-ichi Tanaka; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Lens epithelial cell outgrowth and matrix formation on intraocular lenses in rabbit eyes.
Journal of cataract and refractive surgery 1996;22 Suppl 1():835-40.
1996: Shizuya Saika; Akira Ooshima; K Shima; Sai-ichi Tanaka; Yoshitaka Ohnishi
Collagen types in healing alkali-burned corneal stroma in rabbits.
Japanese journal of ophthalmology 1996;40(3):303-9.
1996: Shizuya Saika; Osamu Yamanaka; Yuka Okada; Sai-ichi Tanaka; Yoshitaka Ohnishi; Akira Ooshima
Pentoxifylline and pentifylline inhibit proliferation of human Tenon's capsule fibroblasts and production of type-I collagen and laminin in vitro.
Ophthalmic research 1996;28(3):165-70.
1995: Shizuya Saika; Akio Yamanaka; Sai-ichi Tanaka; Shunsaku Ohmi; Yoshitaka Ohnishi; Akira Ooshima
Extracellular matrix on intraocular lenses.
Experimental eye research 1995;61(6):713-21.
1995: Shizuya Saika; Akira Ooshima; Natsuko Hashizume; Osamu Yamanaka; Sai-ichi Tanaka; Yuka Okada; S Kobata
Effect of lysyl hydroxylase inhibitor, minoxidil, on ultrastructure and behavior of cultured rabbit subconjunctival fibroblasts.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1995;233(6):347-53.
1995: Shizuya Saika; Akira Ooshima; Osamu Yamanaka; Sai-ichi Tanaka; Yuka Okada; Natsuko Hashizume; Yoshitaka Ohnishi
Effect of a prolyl hydroxylase inhibitor on rabbit ocular fibroblasts.
Ophthalmic research 1995;27(6):335-46.
1995: Shizuya Saika; S Kobata; Natsuko Hashizume; Osamu Yamanaka; Yuka Okada; Akira Ooshima
Type IV collagen in the basement membrane of the corneal epithelium after alkali burns in guinea pigs.
Ophthalmic research 1995;27(3):129-35.
1994: Shizuya Saika; Natsuko Hashizume; Yuka Okada; S Kobata; Osamu Yamanaka; K Uenoyama; Akira Ooshima
Prolyl hydroxylase inhibitor and lysyl hydroxylase inhibitor inhibit spreading of corneal epithelium.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1994;232(8):499-502.
1993: Shizuya Saika; Osamu Yamanaka; Natsuko Hashizume; S Kobata; Yuka Okada; K Uenoyama; Akira Ooshima
Cis-hydroxyproline inhibits adhesion, migration and proliferation of cultured rabbit keratocytes.
Ophthalmic research 1993;25(6):363-70.
1992: Shizuya Saika; K Uenoyama; K Hiroi; Akira Ooshima
L-ascorbic acid 2-phosphate enhances the production of type I and type III collagen peptides in cultured rabbit keratocytes.
Ophthalmic research 1992;24(2):68-72.
1991: Shizuya Saika; K Uenoyama; K Hiroi; Akira Ooshima
[Effect of L-ascorbic acid 2-phosphate on cultured rabbit keratocytes (the third report). The effect on production and secretion of type I collagen].
Nippon Ganka Gakkai zasshi 1991;95(9):835-40.