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Joost Oppenheim

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
42
Wang, Ji Ming
40
Howard, Zack
24
Yang, De
15
Kelvin, David
15
Chertov, Oleg
14
Gong, Wanghua
13
Murphy, William
12
Dong, Hui Fang
10
Salcedo, Rosalba
9
Ben-Baruch, A
8
Grimm, MC
8
Rogers, Thomas
7
Su, SB
7
Chen, Qian
6
Biragyn, Arya

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Publications

TOP 3
Yoshimura Teizo; Oppenheim Joost J
Chemerin reveals its chimeric nature.
de la Rosa Gonzalo; Yang De; Tewary Poonam; Varadhachary Atul; Oppenheim Joost J
Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses.
Yang De; Chen Qian; Su Shao Bo; Zhang Ping; Kurosaka Kahori; Caspi Rachel R; Michalek Suzanne M; Rosenberg Helene F; Zhang Ning; Oppenheim Joost J
Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses.

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All Publications

2008: Yoshimura Teizo; Oppenheim Joost J
Chemerin reveals its chimeric nature.
The Journal of experimental medicine 2008;205(10):2187-90.
2008: de la Rosa Gonzalo; Yang De; Tewary Poonam; Varadhachary Atul; Oppenheim Joost J
Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(10):6868-76.
2008: Yang De; Chen Qian; Su Shao Bo; Zhang Ping; Kurosaka Kahori; Caspi Rachel R; Michalek Suzanne M; Rosenberg Helene F; Zhang Ning; Oppenheim Joost J
Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses.
The Journal of experimental medicine 2008;205(1):79-90.
2007: Hu Paul Q; Hurwitz Arthur A; Oppenheim Joost J
Immunization with DNA topoisomerase I induces autoimmune responses but not scleroderma-like pathologies in mice.
The Journal of rheumatology 2007;34(11):2243-52.
2007: Oppenheim Joost J
IL-2: more than a T cell growth factor.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):1413-4.
2007: Yang De; Chen Qian; Yang Huan; Tracey Kevin J; Bustin Michael; Oppenheim Joost J
High mobility group box-1 protein induces the migration and activation of human dendritic cells and acts as an alarmin.
Journal of leukocyte biology 2007;81(1):59-66.
2007: Yang De; Liu Zhen-hua; Tewary Poonam; Chen Qian; de la Rosa Gonzalo; Oppenheim Joost J
Defensin participation in innate and adaptive immunity.
Current pharmaceutical design 2007;13(30):3131-9.
2007: Oppenheim Joost J; Tewary Poonam; de la Rosa Gonzalo; Yang De
Alarmins initiate host defense.
Advances in experimental medicine and biology 2007;601():185-94.
2006: Chen Xin; Yang Lu; Howard O M Zack; Oppenheim Joost J
Dendritic cells as a pharmacological target of traditional Chinese medicine.
Cellular & molecular immunology 2006;3(6):401-10.
2006: Wang Zhao Yuan; Yang De; Chen Qian; Leifer Cindy A; Segal David M; Su Shao Bo; Caspi Rachel R; Howard Zack O M; Oppenheim Joost J
Induction of dendritic cell maturation by pertussis toxin and its B subunit differentially initiate Toll-like receptor 4-dependent signal transduction pathways.
Experimental hematology 2006;34(8):1115-24.
2006: Chen Xin; Oppenheim Joost J; Winkler-Pickett Robin T; Ortaldo John R; Howard O M Zack
Glucocorticoid amplifies IL-2-dependent expansion of functional FoxP3(+)CD4(+)CD25(+) T regulatory cells in vivo and enhances their capacity to suppress EAE.
European journal of immunology 2006;36(8):2139-49.
2006: Zhang Ning; Yang De; Dong Huifang; Chen Qian; Dimitrova Dessislava I; Rogers Thomas J; Sitkovsky Michail; Oppenheim Joost J
Adenosine A2a receptors induce heterologous desensitization of chemokine receptors.
Blood 2006;108(1):38-44.
2006: Hu Paul Q; Oppenheim Joost J; Medsger Thomas A; Wright Timothy M
T cell lines from systemic sclerosis patients and healthy controls recognize multiple epitopes on DNA topoisomerase I.
Journal of autoimmunity 2006;26(4):258-67.
2006: Chen Xin; Winkler-Pickett Robin T; Carbonetti Nicholas H; Ortaldo John R; Oppenheim Joost J; Howard O M Zack
Pertussis toxin as an adjuvant suppresses the number and function of CD4+CD25+ T regulatory cells.
European journal of immunology 2006;36(3):671-80.
2005: Zhang Ning; Oppenheim Joost J
Crosstalk between chemokines and neuronal receptors bridges immune and nervous systems.
Journal of leukocyte biology 2005;78(6):1210-4.
2005: Gao Ping; Wange Ronald L; Zhang Ning; Oppenheim Joost J; Howard O M Zack
Negative regulation of CXCR4-mediated chemotaxis by the lipid phosphatase activity of tumor suppressor PTEN.
Blood 2005;106(8):2619-26.
2005: Carlos Casey A; Dong Hui Fang; Howard O M Zack; Oppenheim Joost J; Hanisch Franz-Georg; Finn Olivera J
Human tumor antigen MUC1 is chemotactic for immature dendritic cells and elicits maturation but does not promote Th1 type immunity.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1628-35.
2005: Oppenheim Joost J; Yang De
Alarmins: chemotactic activators of immune responses.
Current opinion in immunology 2005;17(4):359-65.
2005: Chen Xin; Oppenheim Joost J; Howard O M Zack
BALB/c mice have more CD4+CD25+ T regulatory cells and show greater susceptibility to suppression of their CD4+CD25- responder T cells than C57BL/6 mice.
Journal of leukocyte biology 2005;78(1):114-21.
2005: Oppenheim Joost J; Dong Hui Fang; Plotz Paul; Caspi Rachel R; Dykstra Michelle; Pierce Susan; Martin Roland; Carlos Casey; Finn Olivera; Koul Omanand; Howard O M Zack
Autoantigens act as tissue-specific chemoattractants.
Journal of leukocyte biology 2005;77(6):854-61.
2005: Howard O M Zack; Dong Hui Fang; Su Shao Bo; Caspi Rachel R; Chen Xin; Plotz Paul; Oppenheim Joost J
Autoantigens signal through chemokine receptors: uveitis antigens induce CXCR3- and CXCR5-expressing lymphocytes and immature dendritic cells to migrate.
Blood 2005;105(11):4207-14.
2005: Kurosaka Kahori; Chen Qian; Yarovinsky Felix; Oppenheim Joost J; Yang De
Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(10):6257-65.
2004: Chung Il Yup; Dong Hui Fang; Zhang Xia; Hassanein Nahed M A; Howard O M Zack; Oppenheim Joost J; Chen Xin
Effects of IL-7 and dexamethasone: induction of CD25, the high affinity IL-2 receptor, on human CD4+ cells.
Cellular immunology 2004;232(1-2):57-63.
2004: Chen Qian; Wade David; Kurosaka Kahori; Wang Zhao Yuan; Oppenheim Joost J; Yang De
Temporin A and related frog antimicrobial peptides use formyl peptide receptor-like 1 as a receptor to chemoattract phagocytes.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(4):2652-9.
2004: Zhang Ning; Rogers Thomas J; Caterina Michael; Oppenheim Joost J
Proinflammatory chemokines, such as C-C chemokine ligand 3, desensitize mu-opioid receptors on dorsal root ganglia neurons.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(1):594-9.
2004: Sun Ronghua; Iribarren Pablo; Zhang Ning; Zhou Ye; Gong Wanghua; Cho Edward H; Lockett Stephen; Chertov Oleg; Bednar Filip; Rogers Thomas J; Oppenheim Joost J; Wang Ji Ming
Identification of neutrophil granule protein cathepsin G as a novel chemotactic agonist for the G protein-coupled formyl peptide receptor.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(1):428-36.
2004: Chen Xin; Krakauer Teresa; Oppenheim Joost J; Howard O M Zack
Yin zi huang, an injectable multicomponent chinese herbal medicine, is a potent inhibitor of T-cell activation.
Journal of alternative and complementary medicine (New York, N.Y.) 2004;10(3):519-26.
2004: Chen Xin; Murakami Takaya; Oppenheim Joost J; Howard O M Zack
Differential response of murine CD4+CD25+ and CD4+CD25- T cells to dexamethasone-induced cell death.
European journal of immunology 2004;34(3):859-69.
2004: Yang De; Biragyn Arya; Hoover David M; Lubkowski Jacek; Oppenheim Joost J
Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense.
Annual review of immunology 2004;22():181-215.
2003: Szabo Imre; Wetzel Michele A; Zhang Ning; Steele Amber D; Kaminsky David E; Chen Chongguang; Liu-Chen Lee-Yuan; Bednar Filip; Henderson Earl E; Howard O M Zack; Oppenheim Joost J; Rogers Thomas J
Selective inactivation of CCR5 and decreased infectivity of R5 HIV-1 strains mediated by opioid-induced heterologous desensitization.
Journal of leukocyte biology 2003;74(6):1074-82.
2003: Oppenheim J J; Biragyn A; Kwak L W; Yang D
Roles of antimicrobial peptides such as defensins in innate and adaptive immunity.
Annals of the rheumatic diseases 2003;62 Suppl 2():ii17-21.
2003: Yang De; Chen Qian; Hoover David M; Staley Patricia; Tucker Kenneth D; Lubkowski Jacek; Oppenheim Joost J
Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.
Journal of leukocyte biology 2003;74(3):448-55.
2003: Salcedo Rosalba; Zhang Xia; Young Howard A; Michael Nelson; Wasserman Ken; Ma Wei-Hong; Martins-Green Manuela; Murphy William J; Oppenheim Joost J
Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells.
Blood 2003;102(6):1966-77.
2003: Chen Xin; Beutler John A; McCloud Thomas G; Loehfelm Amy; Yang Lu; Dong Hui-Fang; Chertov Oleg Y; Salcedo Rosalba; Oppenheim Joost J; Howard O M Zack
Tannic acid is an inhibitor of CXCL12 (SDF-1alpha)/CXCR4 with antiangiogenic activity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(8):3115-23.
2003: Wu Zhibin; Hoover David M; Yang De; Boulègue Cyril; Santamaria Fanny; Oppenheim Joost J; Lubkowski Jacek; Lu Wuyuan
Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(15):8880-5.
2003: Salcedo Rosalba; Oppenheim Joost J
Role of chemokines in angiogenesis: CXCL12/SDF-1 and CXCR4 interaction, a key regulator of endothelial cell responses.
Microcirculation (New York, N.Y. : 1994) 2003;10(3-4):359-70.
2003: Rugeles Maria T; Trubey Charles M; Bedoya Victoria I; Pinto Ligia A; Oppenheim Joost J; Rybak Susanna M; Shearer Gene M
Ribonuclease is partly responsible for the HIV-1 inhibitory effect activated by HLA alloantigen recognition.
AIDS (London, England) 2003;17(4):481-6.
2002: Schneider Gregory P; Salcedo Rosalba; Dong Hui Fang; Kleinman Hynda K; Oppenheim Joost J; Howard O M Zack
Suradista NSC 651016 inhibits the angiogenic activity of CXCL12-stromal cell-derived factor 1alpha.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(12):3955-60.
2002: Biragyn Arya; Ruffini Pier Adelchi; Leifer Cynthia A; Klyushnenkova Elena; Shakhov Alexander; Chertov Oleg; Shirakawa Aiko K; Farber Joshua M; Segal David M; Oppenheim Joost J; Kwak Larry W
Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.
Science (New York, N.Y.) 2002;298(5595):1025-9.
2002: Hoover David M; Boulegue Cyril; Yang De; Oppenheim Joost J; Tucker Kenneth; Lu Wuyuan; Lubkowski Jacek
The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins.
The Journal of biological chemistry 2002;277(40):37647-54.
2002: Howard O M Zack; Dong Hui Fang; Yang De; Raben Nina; Nagaraju Kanneboyina; Rosen Antony; Casciola-Rosen Livia; Härtlein Michael; Kron Michael; Yang David; Yiadom Kwabena; Dwivedi Sunita; Plotz Paul H; Oppenheim Joost J
Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells.
The Journal of experimental medicine 2002;196(6):781-91.
2002: Yang De; Chen Qian; Gertz Barry; He Rong; Phulsuksombati Michele; Ye Richard D; Oppenheim Joost J
Human dendritic cells express functional formyl peptide receptor-like-2 (FPRL2) throughout maturation.
Journal of leukocyte biology 2002;72(3):598-607.
2002: Salcedo Rosalba; Martins-Green Manuela; Gertz Barry; Oppenheim Joost J; Murphy William J
Combined administration of antibodies to human interleukin 8 and epidermal growth factor receptor results in increased antimetastatic effects on human breast carcinoma xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(8):2655-65.
2002: Szabo Imre; Chen Xiao-Hong; Xin Li; Adler Martin W; Howard O M Z; Oppenheim Joost J; Rogers Thomas J
Heterologous desensitization of opioid receptors by chemokines inhibits chemotaxis and enhances the perception of pain.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10276-81.
2002: Yang De; Biragyn Arya; Kwak Larry W; Oppenheim Joost J
Mammalian defensins in immunity: more than just microbicidal.
Trends in immunology 2002;23(6):291-6.
2002: Chen Xin; Howard O M Zack; Yang Xiaoyi; Wang Lihua; Oppenheim Joost J; Krakauer Teresa
Effects of Shuanghuanglian and Qingkailing, two multi-components of traditional Chinese medicinal preparations, on human leukocyte function.
Life sciences 2002;70(24):2897-913.
2002: Chen Xin; Yang Lu; Oppenheim Joost J; Howard M Zack
Cellular pharmacology studies of shikonin derivatives.
Phytotherapy research : PTR 2002;16(3):199-209.
2002: Chen Xin; Mellon Richard Daniel; Yang Lu; Dong Huifang; Oppenheim Joost J; Howard Ola Mae Zack
Regulatory effects of deoxycholic acid, a component of the anti-inflammatory traditional Chinese medicine Niuhuang, on human leukocyte response to chemoattractants.
Biochemical pharmacology 2002;63(3):533-41.
2002: Oppenheim Joost J; Yang De; Biragyn Arya; Howard O M Zack; Plotz Paul
Chemokine receptors on dendritic cells promote autoimmune reactions.
Arthritis research 2002;4 Suppl 3():S183-8.
2001: Biragyn A; Surenhu M; Yang D; Ruffini P A; Haines B A; Klyushnenkova E; Oppenheim J J; Kwak L W
Mediators of innate immunity that target immature, but not mature, dendritic cells induce antitumor immunity when genetically fused with nonimmunogenic tumor antigens.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(11):6644-53.
2001: Yazawa H; Yu Z X; Takeda; Le Y; Gong W; Ferrans V J; Oppenheim J J; Li C C; Wang J M
Beta amyloid peptide (Abeta42) is internalized via the G-protein-coupled receptor FPRL1 and forms fibrillar aggregates in macrophages.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(13):2454-62.
2001: Oppenheim J J
Cytokines: past, present, and future.
International journal of hematology 2001;74(1):3-8.
2001: Yang D; Chertov O; Oppenheim J J
The role of mammalian antimicrobial peptides and proteins in awakening of innate host defenses and adaptive immunity.
Cellular and molecular life sciences : CMLS 2001;58(7):978-89.
2001: Salcedo R; Young H A; Ponce M L; Ward J M; Kleinman H K; Murphy W J; Oppenheim J J
Eotaxin (CCL11) induces in vivo angiogenic responses by human CCR3+ endothelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7571-8.
2001: Yang D; Chertov O; Oppenheim J J
Participation of mammalian defensins and cathelicidins in anti-microbial immunity: receptors and activities of human defensins and cathelicidin (LL-37).
Journal of leukocyte biology 2001;69(5):691-7.
2001: Tani K; Murphy W J; Chertov O; Oppenheim J J; Wang J M
The neutrophil granule protein cathepsin G activates murine T lymphocytes and upregulates antigen-specific IG production in mice.
Biochemical and biophysical research communications 2001;282(4):971-6.
2001: Le Y; Oppenheim J J; Wang J M
Pleiotropic roles of formyl peptide receptors.
Cytokine & growth factor reviews 2001;12(1):91-105.
2001: Yang D; Chen Q; Le Y; Wang J M; Oppenheim J J
Differential regulation of formyl peptide receptor-like 1 expression during the differentiation of monocytes to dendritic cells and macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(6):4092-8.
2001: Chen X; Oppenheim J; Howard O M
Shikonin, a component of antiinflammatory Chinese herbal medicine, selectively blocks chemokine binding to CC chemokine receptor-1.
International immunopharmacology 2001;1(2):229-36.
2001: Le Y; Gong W; Tiffany H L; Tumanov A; Nedospasov S; Shen W; Dunlop N M; Gao J L; Murphy P M; Oppenheim J J; Wang J M
Amyloid (beta)42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(2):RC123.
2001: Howard O M; Dong H F; Oppenheim J J; Insaf S; Santhosh K C; Paul G; Cushman M
Inhibition of RANTES/CCR1-mediated chemotaxis by cosalane and related compounds.
Bioorganic & medicinal chemistry letters 2001;11(1):59-62.
2001: Szabo I; Wetzel M; McCarthy L; Steele A; Henderson E E; Howard M Z; Oppenheim J J; Rogers T J
Interactions of opioid receptors, chemokines, and chemokine receptors.
Advances in experimental medicine and biology 2001;493():69-74.
2000: Chen X; Yang D; Shen W; Dong H F; Wang J M; Oppenheim J J; Howard M Z
Characterization of chenodeoxycholic acid as an endogenous antagonist of the G-coupled formyl peptide receptors.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2000;49(12):744-55.
2000: Chertov O; Yang D; Howard O M; Oppenheim J J
Leukocyte granule proteins mobilize innate host defenses and adaptive immune responses.
Immunological reviews 2000;177():68-78.
2000: Le Y; Li B; Gong W; Shen W; Hu J; Dunlop N M; Oppenheim J J; Wang J M
Novel pathophysiological role of classical chemotactic peptide receptors and their communications with chemokine receptors.
Immunological reviews 2000;177():185-94.
2000: Salcedo R; Resau J H; Halverson D; Hudson E A; Dambach M; Powell D; Wasserman K; Oppenheim J J
Differential expression and responsiveness of chemokine receptors (CXCR1-3) by human microvascular endothelial cells and umbilical vein endothelial cells.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(13):2055-64.
2000: Shen W; Li B; Wetzel M A; Rogers T J; Henderson E E; Su S B; Gong W; Le Y; Sargeant R; Dimitrov D S; Oppenheim J J; Wang J M
Down-regulation of the chemokine receptor CCR5 by activation of chemotactic formyl peptide receptor in human monocytes.
Blood 2000;96(8):2887-94.
2000: De Yang; Chen Q; Schmidt A P; Anderson G M; Wang J M; Wooters J; Oppenheim J J; Chertov O
LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells.
The Journal of experimental medicine 2000;192(7):1069-74.
2000: Hoover D M; Rajashankar K R; Blumenthal R; Puri A; Oppenheim J J; Chertov O; Lubkowski J
The structure of human beta-defensin-2 shows evidence of higher order oligomerization.
The Journal of biological chemistry 2000;275(42):32911-8.
2000: Yang D; Chen Q; Stoll S; Chen X; Howard O M; Oppenheim J J
Differential regulation of responsiveness to fMLP and C5a upon dendritic cell maturation: correlation with receptor expression.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(5):2694-702.
2000: Howard O M; Dong H F; Shirakawa A K; Oppenheim J J
LEC induces chemotaxis and adhesion by interacting with CCR1 and CCR8.
Blood 2000;96(3):840-5.
2000: Yang D; Chen Q; Chertov O; Oppenheim J J
Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells.
Journal of leukocyte biology 2000;68(1):9-14.
2000: Salcedo R; Ponce M L; Young H A; Wasserman K; Ward J M; Kleinman H K; Oppenheim J J; Murphy W J
Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression.
Blood 2000;96(1):34-40.
2000: Tani K; Murphy W J; Chertov O; Salcedo R; Koh C Y; Utsunomiya I; Funakoshi S; Asai O; Herrmann S H; Wang J M; Kwak L W; Oppenheim J J
Defensins act as potent adjuvants that promote cellular and humoral immune responses in mice to a lymphoma idiotype and carrier antigens.
International immunology 2000;12(5):691-700.
2000: Rogers T J; Steele A D; Howard O M; Oppenheim J J
Bidirectional heterologous desensitization of opioid and chemokine receptors.
Annals of the New York Academy of Sciences 2000;917():19-28.
1999: Yang D; Chertov O; Bykovskaia S N; Chen Q; Buffo M J; Shogan J; Anderson M; Schröder J M; Wang J M; Howard O M; Oppenheim J J
Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6.
Science (New York, N.Y.) 1999;286(5439):525-8.
1999: Wang J M; Oppenheim J J
Interference with the signaling capacity of CC chemokine receptor 5 can compromise its role as an HIV-1 entry coreceptor in primary T lymphocytes.
The Journal of experimental medicine 1999;190(5):591-5.
1999: Dean M; Jacobson L P; McFarlane G; Margolick J B; Jenkins F J; Howard O M; Dong H F; Goedert J J; Buchbinder S; Gomperts E; Vlahov D; Oppenheim J J; O'Brien S J; Carrington M
Reduced risk of AIDS lymphoma in individuals heterozygous for the CCR5-delta32 mutation.
Cancer research 1999;59(15):3561-4.
1999: Yang D; Howard O M; Chen Q; Oppenheim J J
Cutting edge: immature dendritic cells generated from monocytes in the presence of TGF-beta 1 express functional C-C chemokine receptor 6.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(4):1737-41.
1999: Bertini R; Howard O M; Dong H F; Oppenheim J J; Bizzarri C; Sergi R; Caselli G; Pagliei S; Romines B; Wilshire J A; Mengozzi M; Nakamura H; Yodoi J; Pekkari K; Gurunath R; Holmgren A; Herzenberg L A; Herzenberg L A; Ghezzi P
Thioredoxin, a redox enzyme released in infection and inflammation, is a unique chemoattractant for neutrophils, monocytes, and T cells.
The Journal of experimental medicine 1999;189(11):1783-9.
1999: Su S B; Gong W; Grimm M; Utsunomiya I; Sargeant R; Oppenheim J J; Ming Wang J
Inhibition of tyrosine kinase activation blocks the down-regulation of CXC chemokine receptor 4 by HIV-1 gp120 in CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):7128-32.
1999: Howard O M; Shirakawa A K; Turpin J A; Maynard A; Tobin G J; Carrington M; Oppenheim J J; Dean M
Naturally occurring CCR5 extracellular and transmembrane domain variants affect HIV-1 Co-receptor and ligand binding function.
The Journal of biological chemistry 1999;274(23):16228-34.
1999: Su S B; Gong W H; Gao J L; Shen W P; Grimm M C; Deng X; Murphy P M; Oppenheim J J; Wang J M
T20/DP178, an ectodomain peptide of human immunodeficiency virus type 1 gp41, is an activator of human phagocyte N-formyl peptide receptor.
Blood 1999;93(11):3885-92.
1999: Su S B; Gao J l; Gong W h; Dunlop N M; Murphy P M; Oppenheim J J; Wang J M
T21/DP107, A synthetic leucine zipper-like domain of the HIV-1 envelope gp41, attracts and activates human phagocytes by using G-protein-coupled formyl peptide receptors.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(10):5924-30.
1999: Salcedo R; Wasserman K; Young H A; Grimm M C; Howard O M; Anver M R; Kleinman H K; Murphy W J; Oppenheim J J
Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1alpha.
The American journal of pathology 1999;154(4):1125-35.
1999: Su S B; Gong W; Gao J L; Shen W; Murphy P M; Oppenheim J J; Wang J M
A seven-transmembrane, G protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells.
The Journal of experimental medicine 1999;189(2):395-402.
1999: Su S B; Ueda H; Howard O M; Grimm M C; Gong W; Ruscetti F W; Oppenheim J J; Wang J M
Inhibition of the expression and function of chemokine receptors on human CD4+ leukocytes by HIV-1 envelope protein gp120.
Chemical immunology 1999;72():141-60.
1998: Wang J M; Ueda H; Howard O M; Grimm M C; Chertov O; Gong X; Gong W; Resau J H; Broder C C; Evans G; Arthur L O; Ruscetti F W; Oppenheim J J
HIV-1 envelope gp120 inhibits the monocyte response to chemokines through CD4 signal-dependent chemokine receptor down-regulation.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):4309-17.
1998: Ueda H; Howard O M; Grimm M C; Su S B; Gong W; Evans G; Ruscetti F W; Oppenheim J J; Wang J M
HIV-1 envelope gp41 is a potent inhibitor of chemoattractant receptor expression and function in monocytes.
The Journal of clinical investigation 1998;102(4):804-12.
1998: Grimm M C; Ben-Baruch A; Taub D D; Howard O M; Resau J H; Wang J M; Ali H; Richardson R; Snyderman R; Oppenheim J J
Opiates transdeactivate chemokine receptors: delta and mu opiate receptor-mediated heterologous desensitization.
The Journal of experimental medicine 1998;188(2):317-25.
1998: Howard O M; Korte T; Tarasova N I; Grimm M; Turpin J A; Rice W G; Michejda C J; Blumenthal R; Oppenheim J J
Small molecule inhibitor of HIV-1 cell fusion blocks chemokine receptor-mediated function.
Journal of leukocyte biology 1998;64(1):6-13.
1998: Grimm M C; Ben-Baruch A; Taub D D; Howard O M; Wang J M; Oppenheim J J
Opiate inhibition of chemokine-induced chemotaxis.
Annals of the New York Academy of Sciences 1998;840():9-20.
1998: Wang J M; Chertov O; Proost P; Li J J; Menton P; Xu L; Sozzani S; Mantovani A; Gong W; Schirrmacher V; Van Damme J; Oppenheim J J
Purification and identification of chemokines potentially involved in kidney-specific metastasis by a murine lymphoma variant: induction of migration and NFkappaB activation.
International journal of cancer. Journal international du cancer 1998;75(6):900-7.
1998: Tani K; Su S B; Utsunomiya I; Oppenheim J J; Wang J M
Interferon-gamma maintains the binding and functional capacity of receptors for IL-8 on cultured human T cells.
European journal of immunology 1998;28(2):502-7.
1998: Gong W; Howard O M; Turpin J A; Grimm M C; Ueda H; Gray P W; Raport C J; Oppenheim J J; Wang J M
Monocyte chemotactic protein-2 activates CCR5 and blocks CD4/CCR5-mediated HIV-1 entry/replication.
The Journal of biological chemistry 1998;273(8):4289-92.
1997: Oppenheim J J; Murphy W J; Chertox O; Schirrmacher V; Wang J M
Prospects for cytokine and chemokine biotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(12 Pt 2):2682-6.
1997: Chertov O; Ueda H; Xu L L; Tani K; Murphy W J; Wang J M; Howard O M; Sayers T J; Oppenheim J J
Identification of human neutrophil-derived cathepsin G and azurocidin/CAP37 as chemoattractants for mononuclear cells and neutrophils.
The Journal of experimental medicine 1997;186(5):739-47.
1997: Utsunomiya I; Tani K; Gong W; Oppenheim J J; Wang J M
Differential expression of binding sites for chemokine RANTES on human T lymphocytes.
European journal of immunology 1997;27(6):1406-12.
1997: Ben-Baruch A; Grimm M; Bengali K; Evans G A; Chertov O; Wang J M; Howard O M; Mukaida N; Matsushima K; Oppenheim J J
The differential ability of IL-8 and neutrophil-activating peptide-2 to induce attenuation of chemotaxis is mediated by their divergent capabilities to phosphorylate CXCR2 (IL-8 receptor B).
Journal of immunology (Baltimore, Md. : 1950) 1997;158(12):5927-33.
1997: Ben-Baruch A; Bengali K; Tani K; Xu L; Oppenheim J J; Wang J M
IL-8 and NAP-2 differ in their capacities to bind and chemoattract 293 cells transfected with either IL-8 receptor type A or type B.
Cytokine 1997;9(1):37-45.
1996: Chertov O; Michiel D F; Xu L; Wang J M; Tani K; Murphy W J; Longo D L; Taub D D; Oppenheim J J
Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils.
The Journal of biological chemistry 1996;271(6):2935-40.
1996: Lloyd A R; Oppenheim J J; Kelvin D J; Taub D D
Chemokines regulate T cell adherence to recombinant adhesion molecules and extracellular matrix proteins.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(3):932-8.
1995: Lloyd A R; Biragyn A; Johnston J A; Taub D D; Xu L; Michiel D; Sprenger H; Oppenheim J J; Kelvin D J
Granulocyte-colony stimulating factor and lipopolysaccharide regulate the expression of interleukin 8 receptors on polymorphonuclear leukocytes.
The Journal of biological chemistry 1995;270(47):28188-92.
1995: Badolato R; Johnston J A; Wang J M; McVicar D; Xu L L; Oppenheim J J; Kelvin D J
Serum amyloid A induces calcium mobilization and chemotaxis of human monocytes by activating a pertussis toxin-sensitive signaling pathway.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(8):4004-10.
1995: Xu L L; McVicar D W; Ben-Baruch A; Kuhns D B; Johnston J; Oppenheim J J; Wang J M
Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors: binding and signaling of MCP3 through shared as well as unique receptors on monocytes and neutrophils.
European journal of immunology 1995;25(9):2612-7.
1995: Ben-Baruch A; Xu L; Young P R; Bengali K; Oppenheim J J; Wang J M
Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3.
The Journal of biological chemistry 1995;270(38):22123-8.
1995: Xu L; Badolato R; Murphy W J; Longo D L; Anver M; Hale S; Oppenheim J J; Wang J M
A novel biologic function of serum amyloid A. Induction of T lymphocyte migration and adhesion.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(3):1184-90.
1995: Ben-Baruch A; Michiel D F; Oppenheim J J
Signals and receptors involved in recruitment of inflammatory cells.
The Journal of biological chemistry 1995;270(20):11703-6.
1995: Ben-Baruch A; Bengali K M; Biragyn A; Johnston J J; Wang J M; Kim J; Chuntharapai A; Michiel D F; Oppenheim J J; Kelvin D J
Interleukin-8 receptor beta. The role of the carboxyl terminus in signal transduction.
The Journal of biological chemistry 1995;270(16):9121-8.
1995: Xu L; Kelvin D J; Ye G Q; Taub D D; Ben-Baruch A; Oppenheim J J; Wang J M
Modulation of IL-8 receptor expression on purified human T lymphocytes is associated with changed chemotactic responses to IL-8.
Journal of leukocyte biology 1995;57(2):335-42.
1994: Murphy W J; Taub D D; Anver M; Conlon K; Oppenheim J J; Kelvin D J; Longo D L
Human RANTES induces the migration of human T lymphocytes into the peripheral tissues of mice with severe combined immune deficiency.
European journal of immunology 1994;24(8):1823-7.
1994: Johnston J A; Taub D D; Lloyd A R; Conlon K; Oppenheim J J; Kevlin D J
Human T lymphocyte chemotaxis and adhesion induced by vasoactive intestinal peptide.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(4):1762-8.
1994: Badolato R; Wang J M; Murphy W J; Lloyd A R; Michiel D F; Bausserman L L; Kelvin D J; Oppenheim J J
Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes.
The Journal of experimental medicine 1994;180(1):203-9.
1993: Kelvin D J; Michiel D F; Johnston J A; Lloyd A R; Sprenger H; Oppenheim J J; Wang J M
Chemokines and serpentines: the molecular biology of chemokine receptors.
Journal of leukocyte biology 1993;54(6):604-12.
1993: Taub D D; Lloyd A R; Conlon K; Wang J M; Ortaldo J R; Harada A; Matsushima K; Kelvin D J; Oppenheim J J
Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells.
The Journal of experimental medicine 1993;177(6):1809-14.
1993: Wang J M; Hishinuma A; Oppenheim J J; Matsushima K
Studies of binding and internalization of human recombinant monocyte chemotactic and activating factor (MCAF) by monocytic cells.
Cytokine 1993;5(3):264-75.
1993: Taub D D; Oppenheim J J
Review of the chemokine meeting the Third International Symposium of Chemotactic Cytokines.
Cytokine 1993;5(3):175-9.
1993: Wang J M; Sherry B; Fivash M J; Kelvin D J; Oppenheim J J
Human recombinant macrophage inflammatory protein-1 alpha and -beta and monocyte chemotactic and activating factor utilize common and unique receptors on human monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(7):3022-9.
1993: Taub D D; Conlon K; Lloyd A R; Oppenheim J J; Kelvin D J
Preferential migration of activated CD4+ and CD8+ T cells in response to MIP-1 alpha and MIP-1 beta.
Science (New York, N.Y.) 1993;260(5106):355-8.
1993: Wang J M; McVicar D W; Oppenheim J J; Kelvin D J
Identification of RANTES receptors on human monocytic cells: competition for binding and desensitization by homologous chemotactic cytokines.
The Journal of experimental medicine 1993;177(3):699-705.
1993: Lloyd A; Modi W; Sprenger H; Cevario S; Oppenheim J; Kelvin D
Assignment of genes for interleukin-8 receptors (IL8R) A and B to human chromosome band 2q35.
Cytogenetics and cell genetics 1993;63(4):238-40.
1993: Oppenheim J J
Overview of chemokines.
Advances in experimental medicine and biology 1993;351():183-6.
1993: Kelvin D J; Wang J M; McVicar D; Oppenheim J J
Promiscuity of ligand binding in the human chemokine beta receptor family.
Advances in experimental medicine and biology 1993;351():147-53.
1993: Taub D D; Lloyd A R; Wang J M; Oppenheim J J; Kelvin D J
The effects of human recombinant MIP-1 alpha, MIP-1 beta, and RANTES on the chemotaxis and adhesion of T cell subsets.
Advances in experimental medicine and biology 1993;351():139-46.
1992: Lloyd A R; Oppenheim J J
Poly's lament: the neglected role of the polymorphonuclear neutrophil in the afferent limb of the immune response.
Immunology today 1992;13(5):169-72.
1992: Michiel D F; Oppenheim J J
Cytokines as positive and negative regulators of tumor promotion and progression.
Seminars in cancer biology 1992;3(1):3-15.
1991: Cox G W; Chattopadhyay U; Oppenheim J J; Varesio L
IL-4 inhibits the costimulatory activity of IL-2 or picolinic acid but not of lipopolysaccharide on IFN-gamma-treated macrophages.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(11):3809-14.
1991: Oppenheim J J; Zachariae C O; Mukaida N; Matsushima K
Properties of the novel proinflammatory supergene "intercrine" cytokine family.
Annual review of immunology 1991;9():617-48.
1990: Kobayashi Y; Yamamoto K; Saido T; Kawasaki H; Oppenheim J J; Matsushima K
Identification of calcium-activated neutral protease as a processing enzyme of human interleukin 1 alpha.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(14):5548-52.
1990: Zachariae C O; Anderson A O; Thompson H L; Appella E; Mantovani A; Oppenheim J J; Matsushima K
Properties of monocyte chemotactic and activating factor (MCAF) purified from a human fibrosarcoma cell line.
The Journal of experimental medicine 1990;171(6):2177-82.
1990: Samanta A K; Oppenheim J J; Matsushima K
Interleukin 8 (monocyte-derived neutrophil chemotactic factor) dynamically regulates its own receptor expression on human neutrophils.
The Journal of biological chemistry 1990;265(1):183-9.
1990: Hirose K; Zachariae C O; Oppenheim J J; Matsushima K
Induction of gene expression and production of immunomodulating cytokines by PSK in human peripheral blood mononuclear cells.
Lymphokine research 1990;9(4):475-83.
1989: Matsushima K; Oppenheim J J
Interleukin 8 and MCAF: novel inflammatory cytokines inducible by IL 1 and TNF.
Cytokine 1989;1(1):2-13.
1989: Larsen C G; Anderson A O; Oppenheim J J; Matsushima K
Production of interleukin-8 by human dermal fibroblasts and keratinocytes in response to interleukin-1 or tumour necrosis factor.
Immunology 1989;68(1):31-6.
1989: Matsushima K; Larsen C G; DuBois G C; Oppenheim J J
Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line.
The Journal of experimental medicine 1989;169(4):1485-90.
1989: Larsen C G; Anderson A O; Appella E; Oppenheim J J; Matsushima K
The neutrophil-activating protein (NAP-1) is also chemotactic for T lymphocytes.
Science (New York, N.Y.) 1989;243(4897):1464-6.
1989: Samanta A K; Oppenheim J J; Matsushima K
Identification and characterization of specific receptors for monocyte-derived neutrophil chemotactic factor (MDNCF) on human neutrophils.
The Journal of experimental medicine 1989;169(3):1185-9.
1988: Endo Y; Matsushima K; Onozaki K; Oppenheim J J
Role of ornithine decarboxylase in the regulation of cell growth by IL-1 and tumor necrosis factor.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(7):2342-8.
1988: Akahoshi T; Oppenheim J J; Matsushima K
Interleukin 1 stimulates its own receptor expression on human fibroblasts through the endogenous production of prostaglandin(s).
The Journal of clinical investigation 1988;82(4):1219-24.
1988: Matsushima K; Morishita K; Yoshimura T; Lavu S; Kobayashi Y; Lew W; Appella E; Kung H F; Leonard E J; Oppenheim J J
Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor.
The Journal of experimental medicine 1988;167(6):1883-93.
1988: Kobayashi Y; Appella E; Yamada M; Copeland T D; Oppenheim J J; Matsushima K
Phosphorylation of intracellular precursors of human IL-1.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(7):2279-87.
1988: Lew W; Oppenheim J J; Matsushima K
Analysis of the suppression of IL-1 alpha and IL-1 beta production in human peripheral blood mononuclear adherent cells by a glucocorticoid hormone.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(6):1895-902.
1988: Akahoshi T; Oppenheim J J; Matsushima K
Induction of high-affinity interleukin 1 receptor on human peripheral blood lymphocytes by glucocorticoid hormones.
The Journal of experimental medicine 1988;167(3):924-36.
1988: Kawano M; Matsushima K; Masuda A; Oppenheim J J
A major 50-kDa human B-cell growth factor-II induces both Tac antigen expression and proliferation by several types of lymphocytes.
Cellular immunology 1988;111(2):273-86.
1987: Oppenheim J J; Matsushima K; Yoshimura T; Leonard E J
The activities of cytokines are pleiotropic and interdependent.
Immunology letters 1987;16(3-4):179-83.
1987: Matsushima K; Kobayashi Y; Copeland T D; Akahoshi T; Oppenheim J J
Phosphorylation of a cytosolic 65-kDa protein induced by interleukin 1 in glucocorticoid pretreated normal human peripheral blood mononuclear leukocytes.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(10):3367-74.
1987: Matsushima K; Akahoshi T; Oppenheim J J
Regulation of interleukin-1 (IL-1) receptor expression and protein phosphorylation induced by IL-1 stimulation.
Annales de l'Institut Pasteur. Immunology 1987;138(3):478-81.

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