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Michael O'Reilly

Research Profile

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TOP 3
Heath D Skinner; James W Welsh; Jaffer A Ajani; James D Cox; Alfredo E Echeverria; Wayne L Hofstetter; Ritsuko Komaki; Steven H Lin; Matthew R McCurdy; Jeffrey N Myers; Michael S O'Reilly; Vlad C Sandulache; Thomas M Guerrero
Metformin use and improved response to therapy in esophageal adenocarcinoma.
Takeshi Isobe; Satoshi Itasaka; Jörg J Jacoby; Peter J Koo; Daniel Morgensztern; Amir Onn; Michael S O'Reilly; Keiko Shibuya; Tomoaki Shintani; Wenjuan Wu; Roy S Herbst
Evaluation of novel orthotopic nude mouse models for human small-cell lung cancer.
Pierre Saintigny; Luisa M Solis Soto; Ignacio I Wistuba; Li Zhang; Young-Ho Ahn; Carmen Behrens; Yulong Chen; Baruch Erez; Sangeeta Goswami; Roy S Herbst; John V Heymach; Waun Ki Hong; Edward S Kim; Jonathan M Kurie; J Jack Lee; Steven Lin; Scott M Lippman; Diane Liu; Erminia Massarelli; Michael S O'Reilly; Yuan Ping; Ja Seok Koo
CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma.

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All Publications

2013: Heath D Skinner; James W Welsh; Jaffer A Ajani; James D Cox; Alfredo E Echeverria; Wayne L Hofstetter; Ritsuko Komaki; Steven H Lin; Matthew R McCurdy; Jeffrey N Myers; Michael S O'Reilly; Vlad C Sandulache; Thomas M Guerrero
Metformin use and improved response to therapy in esophageal adenocarcinoma.
Acta oncologica (Stockholm, Sweden) 2013;52(5):1002-9.
2013: Takeshi Isobe; Satoshi Itasaka; Jörg J Jacoby; Peter J Koo; Daniel Morgensztern; Amir Onn; Michael S O'Reilly; Keiko Shibuya; Tomoaki Shintani; Wenjuan Wu; Roy S Herbst
Evaluation of novel orthotopic nude mouse models for human small-cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2013;8(2):140-6.
2013: Pierre Saintigny; Luisa M Solis Soto; Ignacio I Wistuba; Li Zhang; Young-Ho Ahn; Carmen Behrens; Yulong Chen; Baruch Erez; Sangeeta Goswami; Roy S Herbst; John V Heymach; Waun Ki Hong; Edward S Kim; Jonathan M Kurie; J Jack Lee; Steven Lin; Scott M Lippman; Diane Liu; Erminia Massarelli; Michael S O'Reilly; Yuan Ping; Ja Seok Koo
CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma.
Cancer research 2013;73(2):571-82.
2012: Osamu Takahashi; Ignacio I Wistuba; Anderson Ryan; Paul D Smith; B Nebiyou Bekele; Anna Biernacka; Baruch Erez; Roy S Herbst; Keiko Hosho; Jörg J Jacoby; Juliane M Jürgensmeier; Ritsuko Komaki; Maria V Korshunova; Michael S O'Reilly
Combined MEK and VEGFR inhibition in orthotopic human lung cancer models results in enhanced inhibition of tumor angiogenesis, growth, and metastasis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(6):1641-54.
2011: Ritsuko Komaki; Zhongxing Liao; Mary Frances McAleer; Luka Milas; Michael S O'Reilly; Xiong Wei; Pamela K Allen; George R Blumenschein; Joe Y Chang; James D Cox; Melenda Jeter; Merrill S Kies
Phase I study of celecoxib with concurrent irinotecan, Cisplatin, and radiation therapy for patients with unresectable locally advanced non-small cell lung cancer.
Frontiers in oncology 2011;1():52.
2010: Jörg J Jacoby; Baruch Erez; Maria V Korshunova; Ryan R Williams; Kazuhisa Furutani; Osamu Takahashi; Lynn Kirkpatrick; Scott M Lippman; Garth Powis; Michael S O'Reilly; Roy S Herbst
Treatment with HIF-1alpha antagonist PX-478 inhibits progression and spread of orthotopic human small cell lung cancer and lung adenocarcinoma in mice.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010;5(7):940-9.
2009: Susan L McGovern; Zhongxing Liao; Mary Bucci; Mary Frances McAleer; Melenda Jeter; Joe Y Chang; Michael S O'Reilly; James D Cox; Pamela K Allen; Ritsuko Komaki
Is sex associated with the outcome of patients treated with radiation for nonsmall cell lung cancer?
Cancer 2009;115(14):3233-42.
2008: Michael S O'Reilly
The interaction of radiation therapy and antiangiogenic therapy.
Cancer journal (Sudbury, Mass.) 2008;14(4):207-13.
2007: Keiko Shibuya; Ritsuko Komaki; Tomoaki Shintani; Satoshi Itasaka; Anderson Ryan; Juliane M Jürgensmeier; Luka Milas; Kian Ang; Roy S Herbst; Michael S O'Reilly
Targeted therapy against VEGFR and EGFR with ZD6474 enhances the therapeutic efficacy of irradiation in an orthotopic model of human non-small-cell lung cancer.
International journal of radiation oncology, biology, physics 2007;69(5):1534-43.
2007: Michael S O'Reilly
Antiangiogenic antithrombin.
Seminars in thrombosis and hemostasis 2007;33(7):660-6.
2007: Wenjuan Wu; Michael S O'Reilly; Robert R Langley; Rachel Tsan; Cheryl H Baker; Neby Bekele; Xi Ming Tang; Amir Onn; Isaiah J Fidler; Roy S Herbst
Expression of epidermal growth factor (EGF)/transforming growth factor-alpha by human lung cancer cells determines their response to EGF receptor tyrosine kinase inhibition in the lungs of mice.
Molecular cancer therapeutics 2007;6(10):2652-63.
2007: Satoshi Itasaka; Ritsuko Komaki; Roy S Herbst; Keiko Shibuya; Tomoaki Shintani; Nancy Hunter; Amir Onn; Corazon D Bucana; Luka Milas; K. Kian Ang; Michael S O'Reilly
Endostatin improves radioresponse and blocks tumor revascularization after radiation therapy for A431 xenografts in mice.
International journal of radiation oncology, biology, physics 2007;67(3):870-8.
2007: Wenjuan Wu; Amir Onn; Takeshi Isobe; Satoshi Itasaka; Robert R Langley; Tomoaki Shitani; Keiko Shibuya; Ritsuko Komaki; Anderson Ryan; Isaiah J Fidler; Roy S Herbst; Michael S O'Reilly
Targeted therapy of orthotopic human lung cancer by combined vascular endothelial growth factor and epidermal growth factor receptor signaling blockade.
Molecular cancer therapeutics 2007;6(2):471-83.
2007: Roy S Herbst; John V Heymach; Michael S O'Reilly; Amir Onn; Anderson Ryan
Vandetanib (ZD6474): an orally available receptor tyrosine kinase inhibitor that selectively targets pathways critical for tumor growth and angiogenesis.
Expert opinion on investigational drugs 2007;16(2):239-49.
2007: Michael S O'Reilly
Antiangiogenesis and vascular endothelial growth factor/vascular endothelial growth factor receptor targeting as part of a combined-modality approach to the treatment of cancer.
International journal of radiation oncology, biology, physics 2007;69(2 Suppl):S64-6.
2006: Michael S O'Reilly
Radiation combined with antiangiogenic and antivascular agents.
Seminars in radiation oncology 2006;16(1):45-50.
2004: Amir Onn; Takeshi Isobe; Wenjuan Wu; Satoshi Itasaka; Tomoaki Shintani; Keiko Shibuya; Yokoi Kenji; Michael S O'Reilly; Isaiah J Fidler; Roy S Herbst
Epidermal growth factor receptor tyrosine kinase inhibitor does not improve paclitaxel effect in an orthotopic mouse model of lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8613-9.
2004: Chandrajit P Raut; Ryan Takamori; Darren W Davis; Bridget Sweeney-Gotsch; Michael S O'Reilly; David J McConkey
Direct effects of recombinant human endostatin on tumor cell IL-8 production are associated with increased endothelial cell apoptosis in an orthotopic model of human pancreatic cancer.
Cancer biology & therapy 2004;3(7):679-87.
2004: Amir Onn; Arlene M Correa; Michael Z Gilcrease; Takeshi Isobe; Erminia Massarelli; Corazon D Bucana; Michael S O'Reilly; Waun Ki Hong; Isaiah J Fidler; Joe B Putnam; Roy S Herbst
Synchronous overexpression of epidermal growth factor receptor and HER2-neu protein is a predictor of poor outcome in patients with stage I non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(1 Pt 1):136-43.
2003: Amir Onn; Takeshi Isobe; Satoshi Itasaka; Wenjuan Wu; Michael S O'Reilly; Waun Ki Hong; Isaiah J Fidler; Roy S Herbst
Development of an orthotopic model to study the biology and therapy of primary human lung cancer in nude mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(15):5532-9.
2003: Roy S Herbst; Michael S O'Reilly
The rationale and potential of combining novel biologic therapies with radiotherapy: focus on non-small cell lung cancer.
Seminars in oncology 2003;30(4 Suppl 9):113-23.
2003: Michael S O'Reilly
Therapeutic strategies using inhibitors of angiogenesis.
Methods in molecular biology (Clifton, N.J.) 2003;223():599-634.
2002: Roy S Herbst; Nizar A Mullani; Darren W Davis; Kenneth R Hess; David J McConkey; Chusilp Charnsangavej; Michael S O'Reilly; Hyung Woo Kim; Cheryl Baker; Jennifer Roach; Lee M Ellis; Asif Rashid; James Pluda; Corazon D Bucana; Timothy L Madden; Hai T Tran; James L Abbruzzese
Development of biologic markers of response and assessment of antiangiogenic activity in a clinical trial of human recombinant endostatin.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(18):3804-14.
2002: Roy S Herbst; Kenneth R Hess; Hai T Tran; Jennifer E Tseng; Nizar A Mullani; Chusilp Charnsangavej; Timothy Madden; Darren W Davis; David J McConkey; Michael S O'Reilly; Lee M Ellis; James Pluda; Waun Ki Hong; James L Abbruzzese
Phase I study of recombinant human endostatin in patients with advanced solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(18):3792-803.
2002: Michael S O'Reilly
The combination of antiangiogenic therapy with other modalities.
Cancer journal (Sudbury, Mass.) 2002;8 Suppl 1():S89-99.