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Torben Ørntoft

Research Profile

Procedures

Devices

Oligonucleotide Array Sequence Analysis

Disorders

Chemicals & Drugs

Physiology

Gene Expression Regulation, Neoplastic

Concepts & Ideas

Genes & Molecular Sequences

Single Nucleotide Polymorphism

Phenomena

Blotting, Western

Co-author Network

Publications

TOP 3
Fabrice Moore; Najib Naamane; Maikel L Colli; Thomas Bouckenooghe; Fernanda Ortis; Esteban N Gurzov; Mariana Igoillo-Esteve; Chantal Mathieu; Gianluca Bontempi; Thomas Thykjaer; Torben F Ørntoft; Decio L Eizirik
STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation.
Jonas D Baandrup; Lars H Markvardsen; Christian D Peters; Uffe K Schou; Jens L Jensen; Nils E Magnusson; Torben F Ørntoft; Mogens Kruhøffer; Simonsen Ulf
Pressure load: the main factor for altered gene expression in right ventricular hypertrophy in chronic hypoxic rats.
Kasper Thorsen; Francisco Mansilla; Troels Schepeler; Bodil Øster; Mads H Rasmussen; Lars Dyrskjøt; Rotem Karni; Martin Akerman; Adrian R Krainer; Søren Laurberg; Claus L Andersen; Torben F Ørntoft
Alternative splicing of SLC39A14 in colorectal cancer is regulated by the Wnt pathway.

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All Publications

2011: Fabrice Moore; Najib Naamane; Maikel L Colli; Thomas Bouckenooghe; Fernanda Ortis; Esteban N Gurzov; Mariana Igoillo-Esteve; Chantal Mathieu; Gianluca Bontempi; Thomas Thykjaer; Torben F Ørntoft; Decio L Eizirik
STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation.
The Journal of biological chemistry 2011;286(2):929-41.
2011: Jonas D Baandrup; Lars H Markvardsen; Christian D Peters; Uffe K Schou; Jens L Jensen; Nils E Magnusson; Torben F Ørntoft; Mogens Kruhøffer; Simonsen Ulf
Pressure load: the main factor for altered gene expression in right ventricular hypertrophy in chronic hypoxic rats.
PloS one 2011;6(1):e15859.
2011: Kasper Thorsen; Francisco Mansilla; Troels Schepeler; Bodil Øster; Mads H Rasmussen; Lars Dyrskjøt; Rotem Karni; Martin Akerman; Adrian R Krainer; Søren Laurberg; Claus L Andersen; Torben F Ørntoft
Alternative splicing of SLC39A14 in colorectal cancer is regulated by the Wnt pathway.
Molecular & cellular proteomics : MCP 2011;10(1):M110.002998.
2010: Anne Sofie Brems-Eskildsen; Karsten Zieger; Helle Toldbod; Cherie Holcomb; Russell Higuchi; Francisco Mansilla; Pia P Munksgaard; Michael Borre; Torben F Ørntoft; Lars Dyrskjøt
Prediction and diagnosis of bladder cancer recurrence based on urinary content of hTERT, SENP1, PPP1CA, and MCM5 transcripts.
BMC cancer 2010;10():646.
2009: Karsten Zieger; Niels Marcussen; Michael Borre; Torben F Ørntoft; Lars Dyrskjøt
Consistent genomic alterations in carcinoma in situ of the urinary bladder confirm the presence of two major pathways in bladder cancer development.
International journal of cancer. Journal international du cancer 2009;125(9):2095-103.
2009: Karina Dalsgaard Sørensen; Peter Johannes Wild; Ashkan Mortezavi; Katja Adolf; Niels Tørring; Sara Heebøll; Benedicte Parm Ulhøi; Peter Ottosen; Tullio Sulser; Thomas Hermanns; Holger Moch; Michael Borre; Torben F Ørntoft; Lars Dyrskjøt
Genetic and epigenetic SLC18A2 silencing in prostate cancer is an independent adverse predictor of biochemical recurrence after radical prostatectomy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(4):1400-10.
2009: Claus L Andersen; Lise Lotte Christensen; K Thorsen; T Schepeler; Flemming Brandt Sørensen; Hein Verspaget; R Simon; Mogens Kruhøffer; Lauri A Aaltonen; Søren Laurberg; Torben F Ørntoft
Dysregulation of the transcription factors SOX4, CBFB and SMARCC1 correlates with outcome of colorectal cancer.
British journal of cancer 2009;100(3):511-23.
2009: Frederikke Lihme Egerod; Annette Bartels; Niels Fristrup; Michael Borre; Torben F Ørntoft; Martin B Oleksiewicz; Nils Brünner; Lars Dyrskjøt
High frequency of tumor cells with nuclear Egr-1 protein expression in human bladder cancer is associated with disease progression.
BMC cancer 2009;9():385.
2008: Torben F Ørntoft; Lars Dyrskjøt
Gene signatures for risk-adapted treatment of bladder cancer.
Scandinavian journal of urology and nephrology. Supplementum 2008;(218):166-74.
2008: Karina Dalsgaard Sørensen; Michael Borre; Torben F Ørntoft; Lars Dyrskjøt; Niels Tørring
Chromosomal deletion, promoter hypermethylation and downregulation of FYN in prostate cancer.
International journal of cancer. Journal international du cancer 2008;122(3):509-19.
2007: Claus L Andersen; Troels Schepeler; Kasper Thorsen; Karin Birkenkamp-Demtröder; Francisco Mansilla; Lauri A Aaltonen; Søren Laurberg; Torben F Ørntoft
Clusterin expression in normal mucosa and colorectal cancer.
Molecular & cellular proteomics : MCP 2007;6(6):1039-48.
2007: Pierre Pirot; Najib Naamane; F Libert; Nils E Magnusson; Torben F Ørntoft; Alessandra K Cardozo; Decio L Eizirik
Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs.
Diabetologia 2007;50(5):1006-14.
2007: Niels Tørring; Michael Borre; K D Sørensen; Claus L Andersen; Carsten Wiuf; Torben F Ørntoft
Genome-wide analysis of allelic imbalance in prostate cancer using the Affymetrix 50K SNP mapping array.
British journal of cancer 2007;96(3):499-506.
2007: Claus L Andersen; Carsten Wiuf; Mogens Kruhøffer; Marianne Korsgaard; Søren Laurberg; Torben F Ørntoft
Frequent occurrence of uniparental disomy in colorectal cancer.
Carcinogenesis 2007;28(1):38-48.
2006: Camilla Fröhlich; Reidar Albrechtsen; Lars Dyrskjøt; Lise Rudkjaer; Torben F Ørntoft; Ulla M Wewer
Molecular profiling of ADAM12 in human bladder cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(24):7359-68.
2006: Jirina Bartkova; Nousin Rezaei; Michalis Liontos; Panagiotis Karakaidos; Dimitris Kletsas; Natalia Issaeva; Leandros-Vassilios F Vassiliou; Evangelos Kolettas; Katerina Niforou; Vassilis C Zoumpourlis; Munenori Takaoka; Hiroshi Nakagawa; Frederic Tort; Kasper Fugger; Fredrik Johansson; Maxwell Sehested; Claus L Andersen; Lars Dyrskjot; Torben F Ørntoft; Jiri Lukas; Christos Kittas; Thomas Helleday; Thanos D Halazonetis; Jiri Bartek; Vassilis G Gorgoulis
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.
Nature 2006;444(7119):633-7.
2006: Philippe Lamy; Claus L Andersen; Lars Dyrskjøt; Niels Tørring; Torben F Ørntoft; Carsten Wiuf
Are microRNAs located in genomic regions associated with cancer?
British journal of cancer 2006;95(10):1415-8.
2006: Torben F Ørntoft; Karsten Zieger; Lars Dyrskjøt
Recent developments in molecular profiling of bladder cancer.
Current opinion in urology 2006;16(5):377-81.
2006: Liselotte Sabroe Ebbesen; Sanne H Olesen; Mogens Kruhøffer; Jørgen Ingerslev; Torben F Ørntoft
Folate deficiency induced hyperhomocysteinemia changes the expression of thrombosis-related genes.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2006;17(4):293-301.
2006: Mads Aaboe; Karin Birkenkamp-Demtroder; Carsten Wiuf; Flemming Brandt Sørensen; Thomas Thykjaer; Guido Sauter; Klaus Møller-Ernst Jensen; Lars Dyrskjøt; Torben F Ørntoft
SOX4 expression in bladder carcinoma: clinical aspects and in vitro functional characterization.
Cancer research 2006;66(7):3434-42.
2006: Mette Gaustadnes; Torben F Ørntoft; Jens Ledet Jensen; Niels Torring
Validation of the use of DNA pools and primer extension in association studies of sporadic colorectal cancer for selection of candidate SNPs.
Human mutation 2006;27(2):187-94.
2005: Karsten Zieger; Lars Dyrskjøt; Carsten Wiuf; Jens Ledet Jensen; Claus L Andersen; Klaus Møller-Ernst Jensen; Torben F Ørntoft
Role of activating fibroblast growth factor receptor 3 mutations in the development of bladder tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7709-19.
2005: Mogens Kruhøffer; Jens Ledet Jensen; Päivi Laiho; Lars Dyrskjøt; Reijo Salovaara; Diego Arango; Karin Birkenkamp-Demtroder; Flemming Brandt Sørensen; Lise Lotte Christensen; L Buhl; Jukka-Pekka Mecklin; Heikki Järvinen; Thomas Thykjaer; Friedrik P Wikman; F Bech-Knudsen; M Juhola; Nina N Nupponen; Søren Laurberg; Claus L Andersen; Lauri A Aaltonen; Torben F Ørntoft
Gene expression signatures for colorectal cancer microsatellite status and HNPCC.
British journal of cancer 2005;92(12):2240-8.
2005: Niels Tørring; Frederik Dagnaes Hansen; Boe Sandahl Sorensen; Torben F Ørntoft; Ebba Nexø
Increase in amphiregulin and epiregulin in prostate cancer xenograft after androgen deprivation-impact of specific HER1 inhibition.
The Prostate 2005;64(1):1-8.
2005: Jirina Bartkova; Zuzana Horejsí; Karen Koed; Alwin Krämer; Frederic Tort; Karsten Zieger; Per Guldberg; Maxwell Sehested; Jahn M Nesland; Claudia Lukas; Torben F Ørntoft; Jiri Lukas; Jiri Bartek
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.
Nature 2005;434(7035):864-70.
2005: Karin Birkenkamp-Demtröder; Ludwig Wagner; Flemming Brandt Sørensen; Lone Bording Astrup; Wolfgang Gartner; Hans Scherübl; Bernhard Heine; Peer Christiansen; Torben F Ørntoft
Secretagogin is a novel marker for neuroendocrine differentiation.
Neuroendocrinology 2005;82(2):121-38.
2005: Nils E Magnusson; Alessandra K Cardozo; Mogens Kruhøffer; Decio L Eizirik; Torben F Ørntoft; Jens Ledet Jensen
Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis.
BMC bioinformatics 2005;6():311.
2004: Jirina Bartkova; Per Guldberg; Kirsten Grønbaek; Karen Koed; Hanne Primdahl; Klaus Møller; Jiri Lukas; Torben F Ørntoft; Jiri Bartek
Aberrations of the Chk2 tumour suppressor in advanced urinary bladder cancer.
Oncogene 2004;23(52):8545-51.
2004: David Vermijlen; Carine Seynaeve; Dianzhong Luo; Mogens Kruhøffer; Decio L Eizirik; Torben F Ørntoft; Eddie Wisse
High-density oligonucleotide array analysis reveals extensive differences between freshly isolated blood and hepatic natural killer cells.
European journal of immunology 2004;34(9):2529-40.
2004: Claus L Andersen; Jens Ledet Jensen; Torben F Ørntoft
Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets.
Cancer research 2004;64(15):5245-50.
2004: Lars Dyrskjøt; Mogens Kruhøffer; Thomas Thykjaer; Niels Marcussen; Jens Ledet Jensen; Klaus Møller; Torben F Ørntoft
Gene expression in the urinary bladder: a common carcinoma in situ gene expression signature exists disregarding histopathological classification.
Cancer research 2004;64(11):4040-8.
2003: Joanne Rasschaert; D Liu; Burak Kutlu; Alessandra K Cardozo; Mogens Kruhøffer; Torben F Ørntoft; Decio L Eizirik
Global profiling of double stranded RNA- and IFN-gamma-induced genes in rat pancreatic beta cells.
Diabetologia 2003;46(12):1641-57.
2003: Torben F Ørntoft; Ole Steen Nielsen
[Comment to the article "Nepotism in peer review of applications for research grants"].
Ugeskrift for laeger 2003;165(48):4638-40.
2003: Burak Kutlu; Alessandra K Cardozo; Martine I Darville; Mogens Kruhøffer; Nils E Magnusson; Torben F Ørntoft; Decio L Eizirik
Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells.
Diabetes 2003;52(11):2701-19.
2003: Lasse Tengbjerg Hansen; Thomas Thykjaer; Torben F Ørntoft; Lene Juel Rasmussen; P Keller; Mogens Spang-Thomsen; Tina Bocker Edmonston; Christoph Schmutte; Richard Fishel; Lone Nørgård Petersen
The role of mismatch repair in small-cell lung cancer cells.
European journal of cancer (Oxford, England : 1990) 2003;39(10):1456-67.
2003: Julio E Celis; Pavel Gromov; Irina Gromova; José M A Moreira; Teresa Cabezón; Noona Ambartsumian; Mariam Grigorian; Eugene Lukanidin; Per thor Straten; Per Guldberg; Jirina Bartkova; Jiri Bartek; Jiri Lukas; Claudia Lukas; Anne E Lykkesfeldt; Marja Jäättelä; Peter Roepstorff; Lars Bolund; Torben F Ørntoft; Nils Brünner; Jens Overgaard; Kerstin Sandelin; Mogens Blichert-Toft; Henning Mouridsen; Fritz Rank
Integrating proteomic and functional genomic technologies in discovery-driven translational breast cancer research.
Molecular & cellular proteomics : MCP 2003;2(6):369-77.
2003: Casper Frederiksen; Steen Knudsen; Søren Laurberg; Torben F Ørntoft
Classification of Dukes' B and C colorectal cancers using expression arrays.
Journal of cancer research and clinical oncology 2003;129(5):263-71.
2003: Päivi Laiho; Tuija Hienonen; Auli Karhu; Lara Lipton; Yan Aalto; Huw J W Thomas; Karin Birkenkamp-Demtroder; Shirley Hodgson; Reijo Salovaara; Jukka-Pekka Mecklin; Heikki Järvinen; Sakari Knuutila; Stephanie Halford; Torben F Ørntoft; Ian Tomlinson; Virpi Launonen; richard Houlston; Lauri A Aaltonen
Genome-wide allelotyping of 104 Finnish colorectal cancers reveals an excess of allelic imbalance in chromosome 20q in familial cases.
Oncogene 2003;22(14):2206-14.
2003: Torben F Ørntoft
[DNA microarrays (DNA chips) used in molecular medical research].
Ugeskrift for laeger 2003;165(8):786-90.
2003: Casper Frederiksen; Mads Aaboe; Lars Dyrskjøt; Søren Laurberg; Hans Wolf; Torben F Ørntoft; Mogens Kruhøffer
Technical evaluation of cDNA microarrays.
APMIS. Supplementum 2003;(109):96-101.
2002: Mariann Christensen; Niels Katballe; Friedrik P Wikman; Hanne Primdahl; Flemming Brandt Sørensen; Søren Laurberg; Torben F Ørntoft
Antibody-based screening for hereditary nonpolyposis colorectal carcinoma compared with microsatellite analysis and sequencing.
Cancer 2002;95(11):2422-30.
2002: John De Vos; Thomas Thykjaer; Karin Tarte; Matthias Ensslen; Pierre Raynaud; Guilhem Requirand; Florence Pellet; Véronique Pantesco; Thierry Rème; Michel Jourdan; Jean-François Rossi; Torben F Ørntoft; Bernard Klein
Comparison of gene expression profiling between malignant and normal plasma cells with oligonucleotide arrays.
Oncogene 2002;21(44):6848-57.
2002: Karin Tarte; John De Vos; Thomas Thykjaer; Fenghuang Zhan; Geneviève Fiol; Valérie Costes; Thierry Rème; Eric Legouffe; Jean-François Rossi; John Shaughnessy; Torben F Ørntoft; Bernard Klein
Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts.
Blood 2002;100(4):1113-22.
2002: Jeppe S Spicker; Friedrik P Wikman; Ming-Lan Lu; Carlos Cordon-Cardo; Christopher Workman; Torben F Ørntoft; Søren Brunak; Steen Knudsen
Neural network predicts sequence of TP53 gene based on DNA chip.
Bioinformatics (Oxford, England) 2002;18(8):1133-4.
2002: Karin Birkenkamp-Demtroder; Lise Lotte Christensen; Sanne Harder Olesen; Casper Frederiksen; Päivi Laiho; Lauri A Aaltonen; Søren Laurberg; Flemming Brandt Sørensen; Rikke Hagemann; Torben F Ørntoft
Gene expression in colorectal cancer.
Cancer research 2002;62(15):4352-63.
2002: David Vermijlen; Dianzhong Luo; Mogens Kruhøffer; Torben F Ørntoft; Peter Kuppen; Eddie Wisse
Is the presence of interleukin-2 receptor alpha in the serum of colorectal liver metastases patients derived from hepatic natural killer cells?
Cancer immunology, immunotherapy : CII 2002;51(5):291-2.
2002: Hanne Primdahl; Hans von der Maase; Flemming Brandt Sørensen; Hans Wolf; Torben F Ørntoft
Immunohistochemical study of the expression of cell cycle regulating proteins at different stages of bladder cancer.
Journal of cancer research and clinical oncology 2002;128(6):295-301.
2002: Hanne Primdahl; Hans von der Maase; Mariann Christensen; Hans Wolf; Torben F Ørntoft
Allelic deletions of Rb and L-myc in urine sediments from patients with bladder tumors or carcinoma in situ.
Oncology reports 2002;9(3):551-5.
2002: Julio E Celis; Pamela Celis; Hildur Palsdottir; Morten Østergaard; Pavel Gromov; Hanne Primdahl; Torben F Ørntoft; Hans Wolf; Ariana Celis; Irina Gromova
Proteomic strategies to reveal tumor heterogeneity among urothelial papillomas.
Molecular & cellular proteomics : MCP 2002;1(4):269-79.
2002: Torben F Ørntoft; Thomas Thykjaer; Frederic M Waldman; Hans Wolf; Julio E Celis
Genome-wide study of gene copy numbers, transcripts, and protein levels in pairs of non-invasive and invasive human transitional cell carcinomas.
Molecular & cellular proteomics : MCP 2002;1(1):37-45.
2002: Niels Katballe; Mariann Christensen; Friedrik P Wikman; Torben F Ørntoft; Søren Laurberg
Frequency of hereditary non-polyposis colorectal cancer in Danish colorectal cancer patients.
Gut 2002;50(1):43-51.
2001: Mikkel W Pedersen; Thomas Thykjaer; Torben F Ørntoft; Lars Damstrup; Hans Skovgaard Poulsen
Profile of differentially expressed genes mediated by the type III epidermal growth factor receptor mutation expressed in a small-cell lung cancer cell line.
British journal of cancer 2001;85(8):1211-8.
2001: Niels Katballe; S Juul; Mariann Christensen; Torben F Ørntoft; Friedrik P Wikman; Søren Laurberg
Patient accuracy of reporting on hereditary non-polyposis colorectal cancer-related malignancy in family members.
The British journal of surgery 2001;88(9):1228-33.
2001: Thomas Thykjaer; M Christensen; A B Clark; L R Hansen; T A Kunkel; Torben F Ørntoft
Functional analysis of the mismatch repair system in bladder cancer.
British journal of cancer 2001;85(4):568-75.
2001: S H Olesen; Thomas Thykjaer; Torben F Ørntoft
Mitotic checkpoint genes hBUB1, hBUB1B, hBUB3 and TTK in human bladder cancer, screening for mutations and loss of heterozygosity.
Carcinogenesis 2001;22(5):813-5.
2001: Niels Katballe; S M Bentzen; Mariann Christensen; Friedrik P Wikman; Torben F Ørntoft; Søren Laurberg
Role of chance in familial aggregation of colorectal cancer.
British journal of cancer 2001;84(8):1084-6.