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Thomas Ortel

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Wei Jiang; Maragatha Kuchibhatla; Cynthia Kuhn; Christopher O'Connor; Thomas L Ortel; Joseph Rogers; Zainab Samad; Richard C Becker; Stephen Boyle; Redford Williams; Eric J Velazquez
Prevalence and clinical characteristics of mental stress-induced myocardial ischemia in patients with coronary heart disease.
Thomas L Ortel
Perioperative management of patients on chronic antithrombotic therapy.
Soheir S Adam; Jennifer R McDuffie; Thomas L Ortel; John W Williams
Comparative effectiveness of warfarin and new oral anticoagulants for the management of atrial fibrillation and venous thromboembolism: a systematic review.

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2013: Wei Jiang; Maragatha Kuchibhatla; Cynthia Kuhn; Christopher O'Connor; Thomas L Ortel; Joseph Rogers; Zainab Samad; Richard C Becker; Stephen Boyle; Redford Williams; Eric J Velazquez
Prevalence and clinical characteristics of mental stress-induced myocardial ischemia in patients with coronary heart disease.
Journal of the American College of Cardiology 2013;61(7):714-22.
2012: Thomas L Ortel
Perioperative management of patients on chronic antithrombotic therapy.
Blood 2012;120(24):4699-705.
2012: Soheir S Adam; Jennifer R McDuffie; Thomas L Ortel; John W Williams
Comparative effectiveness of warfarin and new oral anticoagulants for the management of atrial fibrillation and venous thromboembolism: a systematic review.
Annals of internal medicine 2012;157(11):796-807.
2012: Thomas L Ortel; Margaret Pericak-Vance; Leonardo R Brandão; Doruk Erkan; Susan Hahn; Andra H James; Craig S Kitchens; Roshni Kulkarni; Marilyn J Manco-Johnson; Jeffery Vance
Clinical causes and treatment of the thrombotic storm.
Expert review of hematology 2012;5(6):653-9.
2012: Mark Y Chan; Derek Cyr; Mariko Kajikawa; Min Lin; Joseph Lucas; Arthur Moseley; Thomas L Ortel; J Will Thompson; Hitoshi Ueda; Richard C Becker
Plasma proteomics of patients with non-valvular atrial fibrillation on chronic anti-coagulation with warfarin or a direct factor Xa inhibitor.
Thrombosis and haemostasis 2012;108(6):1180-91.
2012: Sony Jacob; Joseph E Kiss; Hau C Kwaan; Masanori Matsumoto; June M McKoy; Thomas L Ortel; Dilip K Pandey; Zaina P Qureshi; Thomas J Raife; Dennis W Raisch; Gail Rock; Ravindra Sarode; Ivy Weiss; Jeffrey L Winters; X Long Zheng; Patricia M Carey; Fei Chen; Hao Chen; William F Clark; John F Cursio; Constance Danielson; Brianne L Dunn; Yoshihiro Fujimura; John M Armstrong; Nicholas Bandarenko; Sara E Barnato; Charles L Bennett
Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR).
Seminars in thrombosis and hemostasis 2012;38(8):845-53.
2012: Nirmish Shah; Marilyn J Telen; Courtney Thornburg; Thomas L Ortel
Characterization of the hypercoagulable state in patients with sickle cell disease.
Thrombosis research 2012;130(5):e241-5.
2012: Robert W Harrison; Thomas L Ortel; Richard C Becker
To bridge or not to bridge: these are the questions.
Journal of thrombosis and thrombolysis 2012;34(1):31-5.
2012: Thomas L Ortel
Antiphospholipid syndrome: laboratory testing and diagnostic strategies.
American journal of hematology 2012;87 Suppl 1():S75-81.
2012: Deepak Voora; Richard C Becker; Jen-Tsan Chi; Joseph E Lucas; Thomas L Ortel; Geoffrey S Ginsburg
Time-dependent changes in non-COX-1-dependent platelet function with daily aspirin therapy.
Journal of thrombosis and thrombolysis 2012;33(3):246-57.
2012: Thomas L Ortel
Perioperative management of patients on chronic antithrombotic therapy.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2012;2012():529-35.
2011: Deborah A Lewis; Olga M Akay; Jen-Tsan Chi; Geoffrey S Ginsburg; Kouros Owzar; Lulit I Price; Gregg J Stashenko; Thomas L Ortel
Whole blood gene expression analyses in patients with single versus recurrent venous thromboembolism.
Thrombosis research 2011;128(6):536-40.
2011: Benjamin J Miriovsky; Thomas L Ortel
Heparin-induced thrombocytopenia in cancer.
Journal of the National Comprehensive Cancer Network : JNCCN 2011;9(7):781-7.
2011: Michael B Streiff; Gary C Yee; Paula L Bockenstedt; Spero R Cataland; Carolyn Chesney; Charles Eby; John Fanikos; Patrick F Fogarty; Shuwei Gao; Julio Garcia-Aguilar; Samuel Z Goldhaber; Hani Hassoun; Paul Hendrie; Bjorn Holmstrom; Kimberly A Jones; Nicole Kuderer; Jason T Lee; Michael M Millenson; Anne T Neff; Thomas L Ortel; Judy L Smith; Anaadriana Zakarija
Venous thromboembolic disease.
Journal of the National Comprehensive Cancer Network : JNCCN 2011;9(7):714-77.
2010: Shalini L Chudasama; Benjamin Espinasse; Fred Hwang; Rui Qi; Manali Joglekar; Galyna Afonina; Mark R Wiesner; Ian J Welsby; Thomas L Ortel; Gowthami M Arepally
Heparin modifies the immunogenicity of positively charged proteins.
Blood 2010;116(26):6046-53.
2010: Junyang Lou; Thomas J Povsic; Jason D Allen; Stacie D Adams; Shelley Myles; Aijing Z Starr; Thomas L Ortel; Richard C Becker
The effect of aspirin on endothelial progenitor cell biology: preliminary investigation of novel properties.
Thrombosis research 2010;126(3):e175-9.
2010: Beverly H Brummett; Stephen H Boyle; Thomas L Ortel; Richard C Becker; Ilene Siegler; Redford B Williams
Associations of depressive symptoms, trait hostility, and gender with C-reactive protein and interleukin-6 response after emotion recall.
Psychosomatic medicine 2010;72(4):333-9.
2010: Thomas L Ortel
Acquired thrombotic risk factors in the critical care setting.
Critical care medicine 2010;38(2 Suppl):S43-50.
2010: Gowthami M Arepally; Thomas L Ortel
Heparin-induced thrombocytopenia.
Annual review of medicine 2010;61():77-90.
2010: Ian J Welsby; John Um; Carmelo A Milano; Thomas L Ortel; Gowthami M Arepally
Plasmapheresis and heparin reexposure as a management strategy for cardiac surgical patients with heparin-induced thrombocytopenia.
Anesthesia and analgesia 2010;110(1):30-5.
2009: Nicole Kuderer; Thomas L Ortel; Charles W Francis
Impact of venous thromboembolism and anticoagulation on cancer and cancer survival.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(29):4902-11.
2009: Stephanie L Perry; N L Whitlatch; Thomas L Ortel
Heparin-dependent platelet factor 4 antibodies and the impact of renal function on clinical outcomes: a retrospective study in hospitalized patients.
Journal of thrombosis and thrombolysis 2009;28(2):146-50.
2009: Anaadriana Zakarija; Hau C Kwaan; Joel L Moake; Nicholas Bandarenko; Dilip K Pandey; June M McKoy; Paul R Yarnold; Dennis W Raisch; Jeffrey L Winters; Thomas J Raife; John F Cursio; Thanh Ha Luu; Elizabeth A Richey; Matthew J Fisher; Thomas L Ortel; Martin S Tallman; X Long Zheng; Masanori Matsumoto; Yoshihiro Fujimura; Charles L Bennett
Ticlopidine- and clopidogrel-associated thrombotic thrombocytopenic purpura (TTP): review of clinical, laboratory, epidemiological, and pharmacovigilance findings (1989-2008).
Kidney international. Supplement 2009;(112):S20-4.
2009: Thomas L Ortel
Heparin-induced thrombocytopenia: when a low platelet count is a mandate for anticoagulation.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2009;():225-32.
2008: Nicole L Whitlatch; Stephanie L Perry; Thomas L Ortel
Anti-heparin/platelet factor 4 antibody optical density values and the confirmatory procedure in the diagnosis of heparin-induced thrombocytopenia.
Thrombosis and haemostasis 2008;100(4):678-84.
2008: Lawrence D Wagman; Melissa F Baird; Charles L Bennett; Paula L Bockenstedt; Spero R Cataland; John Fanikos; Patrick F Fogarty; Samuel Z Goldhaber; Tejpal S Grover; William Haire; Hani Hassoun; Suzanne Hutchinson; Mohammad Jahanzeb; Jason Lee; Michael L Linenberger; Michael M Millenson; Thomas L Ortel; Riad Salem; Judy L Smith; Michael B Streiff; Suresh Vedantham
Venous thromboembolic disease. NCCN. Clinical practice guidelines in oncology.
Journal of the National Comprehensive Cancer Network : JNCCN 2008;6(8):716-53.
2008: Susan I O'Shea; Murat O Arcasoy; Gregory P Samsa; Sandra E Cummings; Elizabeth H Thames; Richard S Surwit; Thomas L Ortel
Direct-to-patient expert system and home INR monitoring improves control of oral anticoagulation.
Journal of thrombosis and thrombolysis 2008;26(1):14-21.
2008: Thomas L Ortel
Prevention and treatment of deep venous thrombosis.
Vascular 2008;16 Suppl 1():S64-70.
2008: Nicole L Whitlatch; Thomas L Ortel
Thrombophilias: when should we test and how does it help?
Seminars in respiratory and critical care medicine 2008;29(1):25-39.
2007: Elliott Bennett-Guerrero; Tim H Veldman; Allan doctor; Marilyn J Telen; Thomas L Ortel; T Scott Reid; Melissa A Mulherin; Hongmei Zhu; Raymond D Buck; Robert M Califf; Timothy J McMahon
Evolution of adverse changes in stored RBCs.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(43):17063-8.
2007: Charles L Bennett; Benjamin Kim; Anaadriana Zakarija; Nicholas Bandarenko; Dilip K Pandey; Charlie G Buffie; June M McKoy; Amul D Tevar; John F Cursio; Paul R Yarnold; Hau C Kwaan; Davide De Masi; Ravindra Sarode; Thomas J Raife; Joseph E Kiss; Dennis W Raisch; Charles Davidson; J Evan Sadler; Thomas L Ortel; X Long Zheng; Seiji Kato; Masanori Matsumoto; Masahito Uemura; Yoshihiro Fujimura
Two mechanistic pathways for thienopyridine-associated thrombotic thrombocytopenic purpura: a report from the SERF-TTP Research Group and the RADAR Project.
Journal of the American College of Cardiology 2007;50(12):1138-43.
2007: Jacob N Schroder; Mani A Daneshmand; Nestor Villamizar; Rebecca P Petersen; Laura J Blue; Ian J Welsby; Andrew J Lodge; Thomas L Ortel; Joseph G Rogers; Carmelo A Milano
Heparin-induced thrombocytopenia in left ventricular assist device bridge-to-transplant patients.
The Annals of thoracic surgery 2007;84(3):841-5; discussion 845-6.
2007: Ian J Welsby; Thomas L Ortel
Invited commentary.
The Annals of thoracic surgery 2007;84(1):168-9.
2007: Elizabeth F Krakow; Ranjit Goudar; Elizabeth Petzold; Shayela Suvarna; Michael Last; Ian J Welsby; Thomas L Ortel; Gowthami M Arepally
Influence of sample collection and storage on the detection of platelet factor 4-heparin antibodies.
American journal of clinical pathology 2007;128(1):150-5.
2007: Yuval Ramot; Deborah A Lewis; Thomas L Ortel; Mike Streicker; Glenda Moser; Susan Elmore; Sandra M Ward; Shyamal Peddada; Abraham Nyska
Age and dose sensitivities in the 2-butoxyethanol F344 rat model of hemolytic anemia and disseminated thrombosis.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2007;58(5):311-22.
2007: Nicole Dowling; M G Beckman; Marilyn J Manco-Johnson; K Hassell; Claire S Philipp; Lisa A Michaels; Stephan Moll; John A Heit; John A Penner; Roshni Kulkarni; Steven W Pipe; Paula L Bockenstedt; Judith C Andersen; S Crudder; Andra H James; S Zimmerman; Thomas L Ortel
The U.S. Thrombosis and Hemostasis Centers pilot sites program.
Journal of thrombosis and thrombolysis 2007;23(1):1-7.
2006: Stephanie L Perry; Susan I O'Shea; Stephen Byrne; Lynda A Szczech; Thomas L Ortel
A multi-dose pharmacokinetic study of dalteparin in haemodialysis patients.
Thrombosis and haemostasis 2006;96(6):750-5.
2006: Lawrence D Wagman; Melissa F Baird; Charles L Bennett; Paula L Bockenstedt; Spero R Cataland; John Fanikos; Patrick F Fogarty; Samuel Z Goldhaber; Tejpal S Grover; William Haire; Hani Hassoun; Mohammad Jahanzeb; Lawrence L Leung; Michael L Linenberger; Michael Millenson; Thomas L Ortel; Riad Salem; Judy L Smith; Michael B Streiff
Venous thromboembolic disease. Clinical practice guidelines in oncology.
Journal of the National Comprehensive Cancer Network : JNCCN 2006;4(9):838-69.
2006: Andra H James; Leo R Brancazio; Thomas R Gehrig; Andrew Wang; Thomas L Ortel
Low-molecular-weight heparin for thromboprophylaxis in pregnant women with mechanical heart valves.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2006;19(9):543-9.
2006: Gowthami M Arepally; Thomas L Ortel
Clinical practice. Heparin-induced thrombocytopenia.
The New England journal of medicine 2006;355(8):809-17.
2006: Ian J Welsby; Kuiran Jiao; Thomas L Ortel; Charles S Brudney; Anthony M Roche; Elliott Bennett-Guerrero; Tong J Gan
The kaolin-activated Thrombelastograph predicts bleeding after cardiac surgery.
Journal of cardiothoracic and vascular anesthesia 2006;20(4):531-5.
2006: Anil Potti; Andrea Bild; Holly K Dressman; Deborah A Lewis; Joseph R Nevins; Thomas L Ortel
Gene-expression patterns predict phenotypes of immune-mediated thrombosis.
Blood 2006;107(4):1391-6.
2006: Thomas L Ortel
The antiphospholipid syndrome: what are we really measuring? How do we measure it? And how do we treat it?
Journal of thrombosis and thrombolysis 2006;21(1):79-83.
2006: D A Lewis; Mary L Pound; Thomas L Ortel
The reactivity of paired plasma and serum samples are comparable in the anticardiolipin and anti-beta2-glycoprotein-1 ELISAs.
Journal of thrombosis and haemostasis : JTH 2006;4(1):265-7.
2006: Deborah A Lewis; Abraham Nyska; Anil Potti; Heather A Hoke; Keith F Klemp; Sandra M Ward; Shyamal Peddada; Jogin Wu; Thomas L Ortel
Hemostatic activation in a chemically induced rat model of severe hemolysis and thrombosis.
Thrombosis research 2006;118(6):747-53.
2006: Karen E Welty-Wolf; Martha Sue Carraway; Thomas L Ortel; Andrew J Ghio; Steven Idell; Jack Egan; Xiaoyun Zhu; Jin-an Jiao; Hing C Wong; Claude A Piantadosi
Blockade of tissue factor-factor X binding attenuates sepsis-induced respiratory and renal failure.
American journal of physiology. Lung cellular and molecular physiology 2006;290(1):L21-31.
2005: Elizabeth Krakow; Thomas L Ortel
Continuing anticoagulation following venous thromboembolism.
JAMA : the journal of the American Medical Association 2005;294(24):3088; author reply 3088-9.
2005: Stephanie L Perry; Gregory P Samsa; Thomas L Ortel
Point-of-care testing of the international normalized ratio in patients with antiphospholipid antibodies.
Thrombosis and haemostasis 2005;94(6):1196-202.
2005: Anil Potti; Veshana Ramiah; Thomas L Ortel
Thrombophilia and thrombosis in thrombotic thrombocytopenic purpura.
Seminars in thrombosis and hemostasis 2005;31(6):652-8.
2005: Elliott Bennett-Guerrero; Thomas F Slaughter; William D White; Ian J Welsby; Charles S Greenberg; Habib El-Moalem; Thomas L Ortel
Preoperative anti-PF4/heparin antibody level predicts adverse outcome after cardiac surgery.
The Journal of thoracic and cardiovascular surgery 2005;130(6):1567-72.
2005: Barton F Haynes; Judith Fleming; E William St Clair; Hermann Katinger; Gabriela Stiegler; Renate Kunert; James Robinson; Richard M Scearce; Kelly Plonk; Herman F Staats; Thomas L Ortel; Hua-Xin Liao; S Munir Alam
Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.
Science (New York, N.Y.) 2005;308(5730):1906-8.
2005: Deborah A Lewis; Niels Bovenschen; Koen Mertens; Jan Voorberg; Thomas L Ortel
Phospholipid vesicles interfere with the binding of antibody fragments to the light chain of factor VIII.
Thrombosis and haemostasis 2005;93(5):833-41.
2005: Andrea S Lukes; Stephanie Perry; Thomas L Ortel
von Willebrand's disease diagnosed after menorrhagia worsened from levonorgestrel intrauterine system.
Obstetrics and gynecology 2005;105(5 Pt 2):1223-6.
2005: Andra H James; Leo R Brancazio; Thomas L Ortel
Thrombosis, thrombophilia, and thromboprophylaxis in pregnancy.
Clinical advances in hematology & oncology : H&O 2005;3(3):187-97.
2005: Jeffrey H Lawson; Kellie A Lynn; Reed M Vanmatre; Taymon Domzalski; Keith F Klemp; Thomas L Ortel; Laura E Niklason; William Parker
Antihuman factor V antibodies after use of relatively pure bovine thrombin.
The Annals of thoracic surgery 2005;79(3):1037-8.
2005: Doruk Erkan; Thomas L Ortel; Michael D Lockshin
Warfarin in antiphospholipid syndrome--time to explore new horizons.
The Journal of rheumatology 2005;32(2):208-12.
2005: Thomas L Ortel
Thrombosis and the antiphospholipid syndrome.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2005;():462-8.
2005: Rebecca Costello; Joan Young; Rebecca Burkholder; Joseph Cranston; Thomas L Ortel; Steven Dentali; Richard Cotter; Julie O'Sullivan-Maillet; Bruce Hawkins; W Craig Hooper
Dialogue with patient care organizations.
Thrombosis research 2005;117(1-2):211-22; discussion 223-5.
2005: Thomas L Ortel
Clinical implications for patients on antithrombotic therapy while taking supplements.
Thrombosis research 2005;117(1-2):75-80; discussion 113-5.
2004: Jacob H Rand; Xiao-Xuan Wu; Robert Lapinski; Waander L van Heerde; Chris P M Reutelingsperger; Pojen P Chen; Thomas L Ortel
Detection of antibody-mediated reduction of annexin A5 anticoagulant activity in plasmas of patients with the antiphospholipid syndrome.
Blood 2004;104(9):2783-90.
2004: Anil Potti; Christopher P Rusconi; Bruce A Sullenger; Thomas L Ortel
Regulatable aptamers in medicine: focus on antithrombotic strategies.
Expert opinion on biological therapy 2004;4(10):1641-7.
2004: Andra H James; Andrea S Lukes; Leo R Brancazio; Elizabeth H Thames; Thomas L Ortel
Use of a new platelet function analyzer to detect von Willebrand disease in women with menorrhagia.
American journal of obstetrics and gynecology 2004;191(2):449-55.
2004: Anastasios V Korompilias; Thomas L Ortel; James R Urbaniak
Coagulation abnormalities in patients with hip osteonecrosis.
The Orthopedic clinics of North America 2004;35(3):265-71, vii.
2004: Roger L Lundblad; Ralph A Bradshaw; Don A Gabriel; Thomas L Ortel; Jeffrey Lawson; Kenneth G Mann
A review of the therapeutic uses of thrombin.
Thrombosis and haemostasis 2004;91(5):851-60.
2003: Stephanie L Perry; Susan I O'Shea; Thomas L Ortel
Management of lepirudin therapy for a patient with antiphospholipid antibody syndrome using the whole blood ecarin clot time and activated partial thromboplastin time.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2003;14(6):601-4.
2003: Susan I O'Shea; Jeffrey H Lawson; Donal N Reddan; Michael Murphy; Thomas L Ortel
Hypercoagulable states and antithrombotic strategies in recurrent vascular access site thrombosis.
Journal of vascular surgery 2003;38(3):541-8.
2003: Zuowei Su; Tomonori Izumi; Thomas L Ortel
Prothrombin and beta 2-glycoprotein I frequently contribute to antiphospholipid antibody interactions with phospholipids and the generation of abnormal waveform profiles in coagulation assays.
Thrombosis and haemostasis 2003;90(2):218-26.
2003: Zoë L Larned; Susan I O'Shea; Thomas L Ortel
Heparin-induced thrombocytopenia: clinical presentations and therapeutic management.
Clinical advances in hematology & oncology : H&O 2003;1(6):356-64.
2003: Deborah A Lewis; Karen D Moore; Thomas L Ortel
Binding of factor VIII inhibitors to discrete regions of the factor VIII C2 domain disrupt phospholipid binding.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2003;14(4):361-8.
2003: Deborah A Lewis; Mary L Pound; Thomas L Ortel
Contributions of Asn2198, Met2199, and Phe2200 in the factor VIII C2 domain to cofactor activity, phospholipid-binding, and von Willebrand factor-binding.
Thrombosis and haemostasis 2003;89(5):795-802.
2003: Martha Sue Carraway; Karen E Welty-Wolf; Debra L Miller; Thomas L Ortel; Steven Idell; Andrew J Ghio; Lars C Petersen; Claude A Piantadosi
Blockade of tissue factor: treatment for organ injury in established sepsis.
American journal of respiratory and critical care medicine 2003;167(9):1200-9.
2003: Stephanie L Perry; Thomas L Ortel
Clinical and laboratory evaluation of thrombophilia.
Clinics in chest medicine 2003;24(1):153-70.
2003: Susan I O'Shea; Thomas L Ortel; Eugene C Kovalik
Alternative methods of anticoagulation for dialysis-dependent patients with heparin-induced thrombocytopenia.
Seminars in dialysis 2003;16(1):61-7.
2002: Tomonori Izumi; Mary L Pound; Zuowei Su; G Michael Iverson; Thomas L Ortel
Anti-beta(2)-glycoprotein I antibody-mediated inhibition of activated protein C requires binding of beta(2)-glycoprotein I to phospholipids.
Thrombosis and haemostasis 2002;88(4):620-6.
2002: Christopher P Rusconi; Elizabeth Scardino; Juliana M Layzer; George A Pitoc; Thomas L Ortel; Dougald M Monroe; Bruce A Sullenger
RNA aptamers as reversible antagonists of coagulation factor IXa.
Nature 2002;419(6902):90-4.
2002: Stephan Moll; Thomas L Ortel
Antiphospholipid antibodies.
Archives of internal medicine 2002;162(15):1783-4; author reply 1786-7.
2002: Karen E Welty-Wolf; Martha Sue Carraway; Thomas L Ortel; Claude A Piantadosi
Coagulation and inflammation in acute lung injury.
Thrombosis and haemostasis 2002;88(1):17-25.
2002: Susan I O'Shea; Thomas L Ortel
Issues in the utilization of low molecular weight heparins.
Seminars in hematology 2002;39(3):172-8.
2002: Zuowei Su; Tomonori Izumi; Elizabeth H Thames; Jeffrey H Lawson; Thomas L Ortel
Antiphospholipid antibodies after surgical exposure to topical bovine thrombin.
The Journal of laboratory and clinical medicine 2002;139(6):349-56.
2002: Edward N van den Brink; Wendy S Bril; Ellen A M Turenhout; Marleen Zuurveld; Niels Bovenschen; Marjolein Peters; Thynn Thynn Yee; Koen Mertens; Deborah A Lewis; Thomas L Ortel; Pete Lollar; Dorothea Scandella; Jan Voorberg
Two classes of germline genes both derived from the V(H)1 family direct the formation of human antibodies that recognize distinct antigenic sites in the C2 domain of factor VIII.
Blood 2002;99(8):2828-34.
2002: Zuowei Su; P J Braun; Keith F Klemp; K R Baker; Elizabeth H Thames; Thomas L Ortel
Abnormal optical waveform profiles in coagulation assays from patients with antiphospholipid antibodies.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2002;13(1):7-17.
2002: Susan I O'Shea; Jeffrey J Sands; Sybil A Nudo; Thomas L Ortel
Frequency of anti-heparin-platelet factor 4 antibodies in hemodialysis patients and correlation with recurrent vascular access thrombosis.
American journal of hematology 2002;69(1):72-3.
2001: Karen E Welty-Wolf; Martha Sue Carraway; Debra L Miller; Thomas L Ortel; Mirella Ezban; Andrew J Ghio; Steven Idell; Claude A Piantadosi
Coagulation blockade prevents sepsis-induced respiratory and renal failure in baboons.
American journal of respiratory and critical care medicine 2001;164(10 Pt 1):1988-96.
2001: Jonathan G Schoenecker; R K Johnson; Aaron Lesher; J D Day; Stephanie D Love; Maureane R Hoffman; Thomas L Ortel; William Parker; Jeffrey H Lawson
Exposure of mice to topical bovine thrombin induces systemic autoimmunity.
The American journal of pathology 2001;159(5):1957-69.
2001: Karen E Welty-Wolf; Martha Sue Carraway; Steven Idell; Thomas L Ortel; Mirella Ezban; Claude A Piantadosi
Tissue factor in experimental acute lung injury.
Seminars in hematology 2001;38(4 Suppl 12):35-8.
2001: Jeffrey J Sands; Sybil A Nudo; K D Moore; Thomas L Ortel
Antibodies to prothrombin, factor V, and beta2-glycoprotein I and vascular access thrombosis.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2001;47(5):507-10.
2001: KE Hansen; David F Kong; Karen D Moore; Thomas L Ortel
Risk factors associated with thrombosis in patients with antiphospholipid antibodies.
The Journal of rheumatology 2001;28(9):2018-24.
2001: Tomonori Izumi; Suhng Wook Kim; A Greist; Sandra Macedo-Ribeiro; Pablo Fuentes-Prior; Wolfram Bode; William H Kane; Thomas L Ortel
Fine mapping of inhibitory anti-factor V antibodies using factor V C2 domain mutants. Identification of two antigenic epitopes involved in phospholipid binding.
Thrombosis and haemostasis 2001;85(6):1048-54.
2001: Deborah A Lewis; Karen D Moore; Thomas L Ortel
Factor VIII Arg2304 --> His binds to phosphatidylserine and is a functional cofactor in the factor X-ase complex.
Thrombosis and haemostasis 2001;85(2):260-4.
2001: Thomas L Ortel; M C Mercer; Elizabeth H Thames; Karen D Moore; Jeffrey H Lawson
Immunologic impact and clinical outcomes after surgical exposure to bovine thrombin.
Annals of surgery 2001;233(1):88-96.
2000: Thomas L Ortel; Andra H James; Elizabeth H Thames; Karen D Moore; Charles S Greenberg
Assessment of primary hemostasis by PFA-100 analysis in a tertiary care center.
Thrombosis and haemostasis 2000;84(1):93-7.
1999: Sandra Macedo-Ribeiro; Wolfram Bode; Robert Huber; Mary Ann Quinn-Allen; Suhng Wook Kim; Thomas L Ortel; Gleb P Bourenkov; Hans D Bartunik; Milton T Stubbs; William H Kane; Pablo Fuentes-Prior
Crystal structures of the membrane-binding C2 domain of human coagulation factor V.
Nature 1999;402(6760):434-9.
1999: KE Hansen; Karen D Moore; Thomas L Ortel; Nancy B Allen
Antiphospholipid antibodies in patients with Wegener's granulomatosis and polyarteritis nodosa.
Arthritis and rheumatism 1999;42(10):2250-2.
1999: Suhng Wook Kim; Thomas L Ortel; Mary Ann Quinn-Allen; Lina I Yoo; L Worfolk; X Zhai; Barry R Lentz; William H Kane
Partial glycosylation at asparagine-2181 of the second C-type domain of human factor V modulates assembly of the prothrombinase complex.
Biochemistry 1999;38(35):11448-54.
1999: Thomas L Ortel
Clinical and laboratory manifestations of anti-factor V antibodies.
The Journal of laboratory and clinical medicine 1999;133(4):326-34.
1999: N Goel; Thomas L Ortel; Deeksha Bali; J P Anderson; I S Gourley; H Smith; C A Morris; M DeSimone; D W Branch; P Ford; D Berdeaux; Robert A S Roubey; DD Kostyu; Stephen Kingsmore; T Thiel; Christopher I Amos; Michael F Seldin
Familial antiphospholipid antibody syndrome: criteria for disease and evidence for autosomal dominant inheritance.
Arthritis and rheumatism 1999;42(2):318-27.
1998: Stephan Moll; Thomas L Ortel
Diagnosis of pulmonary embolism.
The New England journal of medicine 1998;339(15):1084.
1998: Thomas L Ortel; Beng H Chong
New treatment options for heparin-induced thrombocytopenia.
Seminars in hematology 1998;35(4 Suppl 5):26-34; discussion 35-6.
1998: Thomas L Ortel
Heparin-induced thrombocytopenia.
Seminars in hematology 1998;35(4 Suppl 5):1-2.
1998: James M Provenzale; Donald P Frush; Thomas L Ortel
Recurrent thrombosis of the superior vena cava associated with activated protein C resistance: imaging findings.
Pediatric radiology 1998;28(8):597-8.
1998: Thomas L Ortel; Karen D Moore; Mary Ann Quinn-Allen; T Okamura; A J Sinclair; John Lazarchick; R Govindan; F Carmagnol; William H Kane
Inhibitory anti-factor V antibodies bind to the factor V C2 domain and are associated with hemorrhagic manifestations.
Blood 1998;91(11):4188-96.
1998: Thomas L Ortel; Stephan Moll
Monitoring oral anticoagulant therapy in patients with lupus anticoagulants.
British journal of haematology 1998;101(2):390-2.
1998: James M Provenzale; Daniel P Barboriak; Nancy B Allen; Thomas L Ortel
Antiphospholipid antibodies: findings at arteriography.
AJNR. American journal of neuroradiology 1998;19(4):611-6.
1998: James M Provenzale; Daniel P Barboriak; I C Davey; Thomas L Ortel
Cerebrovascular disease risk factors: neuroradiologic findings in patients with activated protein C resistance.
Radiology 1998;207(1):85-9.
1998: James M Provenzale; Daniel P Barboriak; Thomas L Ortel
Dural sinus thrombosis associated with activated protein C resistance: MR imaging findings and proband identification.
AJR. American journal of roentgenology 1998;170(2):499-502.
1998: James M Provenzale; Thomas L Ortel; Nancy B Allen
Systemic thrombosis in patients with antiphospholipid antibodies: lesion distribution and imaging findings.
AJR. American journal of roentgenology 1998;170(2):285-90.
1997: Anastasios V Korompilias; Gary S Gilkeson; Thomas L Ortel; Anthony V Seaber; James R Urbaniak
Anticardiolipin antibodies and osteonecrosis of the femoral head.
Clinical orthopaedics and related research 1997;(345):174-80.
1997: CM Hunt; KL Carson; Thomas L Ortel
Combined factor IX and XI deficiency discovered at liver biopsy.
Digestive diseases and sciences 1997;42(8):1731-3.
1997: Stephan Moll; Thomas L Ortel
Monitoring warfarin therapy in patients with lupus anticoagulants.
Annals of internal medicine 1997;127(3):177-85.
1997: Stephan Moll; M McCloud; Thomas L Ortel
Subdural hematoma and lupus anticoagulants.
Stroke; a journal of cerebral circulation 1997;28(3):646-8.
1996: James M Provenzale; Daniel P Barboriak; Nancy B Allen; Thomas L Ortel
Patients with antiphospholipid antibodies: CT and MR findings of the brain.
AJR. American journal of roentgenology 1996;167(6):1573-8.
1996: Stephan Moll; J D Igelhart; Thomas L Ortel
Thrombocytopenia in association with a wandering spleen.
American journal of hematology 1996;53(4):259-63.
1996: Thomas L Ortel; Karen D Moore; M Ezban; William H Kane
Effect of heterologous factor V heavy chain sequences on the secretion of recombinant human factor VIII.
Thrombosis and haemostasis 1996;75(1):36-44.
1995: James M Provenzale; Thomas L Ortel
Anatomic distribution of venous thrombosis in patients with antiphospholipid antibody: imaging findings.
AJR. American journal of roentgenology 1995;165(2):365-8.
1995: James M Provenzale; Thomas L Ortel; Rendon C Nelson
Adrenal hemorrhage in patients with primary antiphospholipid syndrome: imaging findings.
AJR. American journal of roentgenology 1995;165(2):361-4.
1995: B G Macik; Thomas L Ortel
Clinical and laboratory evaluation of the hypercoagulable states.
Clinics in chest medicine 1995;16(2):375-87.
1995: Frank G Keller; Thomas L Ortel; Mary Ann Quinn-Allen; William H Kane
Thrombin-catalyzed activation of recombinant human factor V.
Biochemistry 1995;34(12):4118-24.
1994: Charles S Greenberg; M J Hursting; B G Macik; Thomas L Ortel; William H Kane; B M Moore
Evaluation of preanalytical variables associated with measurement of prothrombin fragment 1.2.
Clinical chemistry 1994;40(10):1962-9.
1994: James M Provenzale; E R Heinz; Thomas L Ortel; B G Macik; L A Charles; M J Alberts
Antiphospholipid antibodies in patients without systemic lupus erythematosus: neuroradiologic findings.
Radiology 1994;192(2):531-7.
1994: L A Charles; D L McGlasson; B A Hawksworth; J H Ashcraft; Thomas L Ortel
Evaluation of a modified procedure for Staclot LA for the confirmation of lupus anticoagulants.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1994;5(4):601-4.
1994: Thomas L Ortel; Mary Ann Quinn-Allen; Frank G Keller; J A Peterson; D Larocca; William H Kane
Localization of functionally important epitopes within the second C-type domain of coagulation factor V using recombinant chimeras.
The Journal of biological chemistry 1994;269(22):15898-905.
1994: Thomas L Ortel; L A Charles; Frank G Keller; Paul Kelly Marcom; H N Oldham; William H Kane; B G Macik
Topical thrombin and acquired coagulation factor inhibitors: clinical spectrum and laboratory diagnosis.
American journal of hematology 1994;45(2):128-35.
1993: Therese Wiedmer; S E Hall; Thomas L Ortel; William H Kane; W F Rosse; Peter J Sims
Complement-induced vesiculation and exposure of membrane prothrombinase sites in platelets of paroxysmal nocturnal hemoglobinuria.
Blood 1993;82(4):1192-6.
1992: Thomas L Ortel; Mary Ann Quinn-Allen; L A Charles; D Devore-Carter; William H Kane
Characterization of an acquired inhibitor to coagulation factor V. Antibody binding to the second C-type domain of factor V inhibits the binding of factor V to phosphatidylserine and neutralizes procoagulant activity.
The Journal of clinical investigation 1992;90(6):2340-7.
1992: Thomas L Ortel; Jon P Gockerman; Robert M Califf; R L McCann; C M O'Connor; D M Metzler; Charles S Greenberg
Parenteral anticoagulation with the heparinoid Lomoparan (Org 10172) in patients with heparin induced thrombocytopenia and thrombosis.
Thrombosis and haemostasis 1992;67(3):292-6.
1992: Thomas L Ortel; D Devore-Carter; Mary Ann Quinn-Allen; William H Kane
Deletion analysis of recombinant human factor V. Evidence for a phosphatidylserine binding site in the second C-type domain.
The Journal of biological chemistry 1992;267(6):4189-98.
1990: Thomas L Ortel; J Kallianos; H A Gallis
Group C streptococcal arthritis: case report and review.
Reviews of infectious diseases 1990;12(5):829-37.
1990: William H Kane; D Devore-Carter; Thomas L Ortel
Expression and characterization of recombinant human factor V and a mutant lacking a major portion of the connecting region.
Biochemistry 1990;29(29):6762-8.
1988: Thomas L Ortel; J J Onorato; C L Bedrosian; Russel E Kaufman
Antifibrinolytic therapy in the management of the Kasabach Merritt syndrome.
American journal of hematology 1988;29(1):44-8.
1987: Thomas L Ortel; C L Bedrosian; D L Simel
Arsenic poisoning and seizures.
North Carolina medical journal 1987;48(12):627-30.