Yoshiyuki Osamura

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Chemicals & Drugs

Anatomy

Pituitary Gland

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Mizutani Ryuta; Takeuchi Akihisa; Osamura R Yoshiyuki; Takekoshi Susumu; Uesugi Kentaro; Suzuki Yoshio
Submicrometer tomographic resolution examined using a micro-fabricated test object.
Hirabayashi Kenichi; Nakamura Naoya; Kajiwara Hiroshi; Hori Sadaaki; Kawaguchi Yoshiaki; Yamashita Tomohiro; Dowaki Shoichi; Imaizumi Toshihide; Osamura Robert Y
Perivascular epithelioid cell tumor (PEComa) of the pancreas: immunoelectron microscopy and review of the literature.
Osamura Robert Y; Egashira Noboru; Kajiya Hanako; Takei Mao; Tobita Maya; Miyakoshi Takashi; Inomoto Chie; Takekoshi Susumu; Teramoto Akira
Pathology, Pathogenesis and Therapy of Growth Hormone (GH)-producing Pituitary Adenomas: Technical Advances in Histochemistry and Their Contribution.

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All Publications

2010: Mizutani Ryuta; Takeuchi Akihisa; Osamura R Yoshiyuki; Takekoshi Susumu; Uesugi Kentaro; Suzuki Yoshio
Submicrometer tomographic resolution examined using a micro-fabricated test object.
Micron (Oxford, England : 1993) 2010;41(1):90-5.
2009: Hirabayashi Kenichi; Nakamura Naoya; Kajiwara Hiroshi; Hori Sadaaki; Kawaguchi Yoshiaki; Yamashita Tomohiro; Dowaki Shoichi; Imaizumi Toshihide; Osamura Robert Y
Perivascular epithelioid cell tumor (PEComa) of the pancreas: immunoelectron microscopy and review of the literature.
Pathology international 2009;59(9):650-5.
2009: Osamura Robert Y; Egashira Noboru; Kajiya Hanako; Takei Mao; Tobita Maya; Miyakoshi Takashi; Inomoto Chie; Takekoshi Susumu; Teramoto Akira
Pathology, Pathogenesis and Therapy of Growth Hormone (GH)-producing Pituitary Adenomas: Technical Advances in Histochemistry and Their Contribution.
Acta histochemica et cytochemica 2009;42(4):95-104.
2009: Miyazawa Masaki; Yasuda Masanori; Fujita Mariko; Hirasawa Takeshi; Kajiwara Hiroshi; Hirabayashi Kenichi; Ogane Naoki; Shimizu Michio; Asanuma Hideki; Murakami Masaru; Takekoshi Susumu; Mikami Mikio; Osamura R Yoshiyuki
Association of hypoxia-inducible factor-1 expression with histology in epithelial ovarian tumors: a quantitative analysis of HIF-1.
Archives of gynecology and obstetrics 2009;279(6):789-96.
2009: Takano Koji; Yasufuku-Takano Junko; Morita Koji; Mori Shigetoshi; Takei Mao; Osamura Robert Yoshiyuki; Teramoto Akira; Fujita Toshiro
Evidence that PKA activity is constitutively activated in human GH-secreting adenoma cells in a patient with Carney complex harbouring a PRKAR1A mutation.
Clinical endocrinology 2009;70(5):769-75.
2009: Kajiwara Hiroshi; Kumaki Nobue; Hirabayashi Kenichi; Miyazawa Masaki; Nakamura Naoya; Hirasawa Takeshi; Muramatsu Toshinari; Mikami Mikio; Yasuda Masanori; Osamura R Y
A case of oncocytic carcinoma of the endometrium.
Archives of gynecology and obstetrics 2009;279(5):733-8.
2009: Kajiwara Hiroshi; Hirabayashi Kenichi; Miyazawa Masaki; Nakamura Naoya; Hirasawa Takeshi; Muramatsu Toshinari; Mikami Mikio; Yasuda Masanori; Osamura R Y
Immunohistochemical expression of somatostatin type 2A receptor in neuroendocrine carcinoma of uterine cervix.
Archives of gynecology and obstetrics 2009;279(4):521-5.
2009: Miyazawa Masaki; Yasuda Masanori; Fujita Mariko; Kajiwara Hiroshi; Hirabayashi Kenichi; Takekoshi Susumu; Hirasawa Takeshi; Murakami Masaru; Ogane Naoki; Kiguchi Kazushige; Ishiwata Isamu; Mikami Mikio; Osamura R Yoshiyuki
Therapeutic strategy targeting the mTOR-HIF-1alpha-VEGF pathway in ovarian clear cell adenocarcinoma.
Pathology international 2009;59(1):19-27.
2008: Umemura Shinobu; Osamura R Yoshiyuki; Akiyama Futoshi; Honma Keiichi; Kurosumi Masafumi; Sasano Hironobu; Toyoshima Satoshi; Tsuda Hitoshi; Rüschoff Josef; Sakamoto Goi
What causes discrepancies in HER2 testing for breast cancer? A Japanese ring study in conjunction with the global standard.
American journal of clinical pathology 2008;130(6):883-91.
2008: Mizutani Ryuta; Takeuchi Akihisa; Uesugi Kentaro; Takekoshi Susumu; Osamura R Yoshiyuki; Suzuki Yoshio
X-ray microtomographic imaging of three-dimensional structure of soft tissues.
Tissue engineering. Part C, Methods 2008;14(4):359-63.
2008: Osamura Robert Y; Kajiya Hanako; Takei Mao; Egashira Noboru; Tobita Maya; Takekoshi Susumu; Teramoto Akira
Pathology of the human pituitary adenomas.
Histochemistry and cell biology 2008;130(3):495-507.
2008: Kakimoto Kochi; Takekoshi Susumu; Miyajima Katsuhiro; Osamura R Yoshiyuki
Hypothesis for the mechanism for heat-induced antigen retrieval occurring on fresh frozen sections without formalin-fixation in immunohistochemistry.
Journal of molecular histology 2008;39(4):389-99.
2008: Egashira Noboru; Minematsu Takeo; Miyai Syunsuke; Takekoshi Susumu; Camper Sally A; Osamura Robert Y
Pituitary changes in Prop1 transgenic mice: hormone producing tumors and signet-ring type gonadotropes.
Acta histochemica et cytochemica 2008;41(3):47-57.
2008: Iida Tetsuji; Yasuda Masanori; Miyazawa Masaki; Fujita Mariko; Osamura R Yoshiyuki; Hirasawa Takeshi; Muramatsu Toshinari; Murakami Masaru; Saito Kaoru; Mikami Mikio
Hypoxic status in ovarian serous and mucinous tumors: relationship between histological characteristics and HIF-1alpha/GLUT-1 expression.
Archives of gynecology and obstetrics 2008;277(6):539-46.
2008: Mizutani Ryuta; Takeuchi Akihisa; Uesugi Kentaro; Ohyama Masami; Takekoshi Susumu; Osamura R Yoshiyuki; Suzuki Yoshio
Three-dimensional microtomographic imaging of human brain cortex.
Brain research 2008;1199():53-61.
2008: Morita Koji; Takano Koji; Yasufuku-Takano Junko; Yamada Shozo; Teramoto Akira; Takei Mao; Osamura Robert Yoshiyuki; Sano Toshiaki; Fujita Toshiro
Expression of pituitary tumour-derived, N-terminally truncated isoform of fibroblast growth factor receptor 4 (ptd-FGFR4) correlates with tumour invasiveness but not with G-protein alpha subunit (gsp) mutation in human GH-secreting pituitary adenomas.
Clinical endocrinology 2008;68(3):435-41.
2008: Kimura Nobuko; Takamatsu Nobuko; Yaoita Yoshio; Osamura R Yoshiyuki; Kimura Narimichi
Identification of transcriptional regulatory elements in the human somatostatin receptor sst2 promoter and regions including estrogen response element half-site for estrogen activation.
Journal of molecular endocrinology 2008;40(2):75-91.
2008: Yasuda Masanori; Miyazawa Masaki; Fujita Mariko; Kajiwara Hiroshi; Iida Tetsuji; Hirasawa Takeshi; Muramatsu Toshinari; Murakami Masaru; Mikami Mikio; Saitoh Kaoru; Shimizu Michio; Takekoshi Susumu; Osamura R Yoshiyuki
Expression of hypoxia inducible factor-1alpha (HIF-1alpha) and glucose transporter-1 (GLUT-1) in ovarian adenocarcinomas: difference in hypoxic status depending on histological character.
Oncology reports 2008;19(1):111-6.
2008: Matsuno Akira; Itoh Johbu; Mizutani Akiko; Takekoshi Susumu; Osamura R Yoshiyuki; Okinaga Hiroko; Ide Fuyuaki; Miyawaki Satoru; Uno Takeshi; Asano Shuichiro; Tanaka Junichi; Nakaguchi Hiroshi; Sasaki Mitsuyoshi; Murakami Mineko
Co-transfection of EYFP-GH and ECFP-rab3B in an experimental pituitary GH3 cell: a role of rab3B in secretion of GH through porosome.
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 2008;46(4):419-21.
2008: Mizokami Yoshihito; Egashira Noboru; Takekoshi Susumu; Itoh Johbu; Itoh Yoshiko; Osamura Robert Yoshiyuki; Matsumae Mitsunori
Expression of MSX1 in human normal pituitaries and pituitary adenomas.
Endocrine pathology 2008;19(1):54-61.
2008: Suzuki Masanori; Egashira Noboru; Kajiya Hanako; Minematsu Takeo; Takekoshi Susumu; Tahara Shigeyuki; Sanno Naoko; Teramoto Akira; Osamura Robert Yoshiyuki
ACTH and alpha-subunit are co-expressed in rare human pituitary corticotroph cell adenomas proposed to originate from ACTH-committed early pituitary progenitor cells.
Endocrine pathology 2008;19(1):17-26.
2007: Kumaki Nobue; Umemura Shinobu; Kajiwara Hiroshi; Itoh Johbu; Itoh Yoshiko; Osamura R Yoshiyuki
Immunohistochemical analysis of neuroendocrine (NE) differentiation in testicular germ cell tumors (GCTs): use of confocal laser scanning microscopy (CLSM) to demonstrate direct NE differentiation from GCTs.
Acta histochemica et cytochemica 2007;40(6):143-51.
2007: Fujita Mariko; Yasuda Masanori; Kitatani Kanae; Miyazawa Masaki; Hirabayashi Kenichi; Takekoshi Susumu; Iida Tetsuji; Hirasawa Takeshi; Murakami Masaru; Mikami Mikio; Ishiwata Isamu; Shimizu Michio; Osamura R Yoshiyuki
An up-to-date anti-cancer treatment strategy focusing on HIF-1alpha suppression: its application for refractory ovarian cancer.
Acta histochemica et cytochemica 2007;40(5):139-42.
2007: Kitano Yuriko; Umemura Shinobu; Ohbayashi Hirokazu; Takenaga Masato; Osamura Robert Yoshiyuki
Assessment of a new anti-HER2 monoclonal antibody, SV2-61gamma: a best concordance with HER2 FISH.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2007;15(4):389-93.
2007: Umemura Shinobu; Yoshida Sei; Ohta Yoshikazu; Naito Kenichiro; Osamura R Yoshiyuki; Tokuda Yutaka
Increased phosphorylation of Akt in triple-negative breast cancers.
Cancer science 2007;98(12):1889-92.
2007: Inomoto Chie; Umemura Shinobu; Egashira Noboru; Minematsu Takeo; Takekoshi Susumu; Itoh Yoshiko; Itoh Johbu; Taupenot Laurent; O'Connor Daniel T; Osamura R Yoshiyuki
Granulogenesis in non-neuroendocrine COS-7 cells induced by EGFP-tagged chromogranin A gene transfection: identical and distinct distribution of CgA and EGFP.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007;55(5):487-93.
2007: Inomoto Chie; Umemura Shinobu; Sasaki Yutaka; Yasuda Masanori; Terachi Toshiro; Osamura R Yoshiyuki
Renal cell carcinoma arising in a long pre-existing angiomyolipoma.
Pathology international 2007;57(3):162-6.
2007: Kamata Yayoi; Itoh Yoshiko; Kajiya Akane; Karasawa Sachiyo; Sakatani Chie; Takekoshi Susumu; Osamura R Yoshiyuki; Takeda Atsushi
Quantification of neutral cysteine protease bleomycin hydrolase and its localization in rat tissues.
Journal of biochemistry 2007;141(1):69-76.
2007: Yasuda Masanori; Shimizu Michio; Fujita Mariko; Miyazawa Masaki; Tang Xiaoyan; Kajiwara Hiroshi; Osamura Robert Yoshiyuki; Shoji Sunao; Tokunaga Masatoshi; Terachi Toshiro
Usefulness of hypoxia inducible factor-1 alpha in evaluating the prostatic adenocarcinoma viability following neoadjuvant hormone therapy.
Cancer detection and prevention 2007;31(5):396-401.
2007: Takei Mao; Suzuki Masanori; Kajiya Hanako; Ishii Yudo; Tahara Shigeyuki; Miyakoshi Takashi; Egashira Noboru; Takekoshi Susumu; Sanno Naoko; Teramoto Akira; Osamura Robert Yoshiyuki
Immunohistochemical detection of somatostatin receptor (SSTR) subtypes 2A and 5 in pituitary adenoma from acromegalic patients: good correlation with preoperative response to octreotide.
Endocrine pathology 2007;18(4):208-16.
2007: Minematsu Takeo; Egashira Noboru; Kajiya Hanako; Takei Mao; Takekoshi Susumu; Itoh Yoshiko; Tsukamoto Hideo; Itoh Johbu; Sanno Naoko; Teramoto Akira; Osamura Robert Yoshiyuki
PTTG is a secretory protein in human pituitary adenomas and in mouse pituitary tumor cell lines.
Endocrine pathology 2007;18(1):8-15.
2007: Itoh Johbu; Osamura Robert Yoshiyuki
Quantum dots for multicolor tumor pathology and multispectral imaging.
Methods in molecular biology (Clifton, N.J.) 2007;374():29-42.
2006: Hasegawa Jun; Takekoshi Susumu; Nagata Hidetaka; Osamura R Yoshiyuki; Suzuki Toshiyasu
Sevoflurane stimulates MAP kinase signal transduction through the activation of PKC alpha and betaII in fetal rat cerebral cortex cultured neuron.
Acta histochemica et cytochemica 2006;39(6):163-72.
2006: Tang Xiaoyan; Serizawa Akihiko; Tokunaga Masatoshi; Yasuda Masanori; Matsushita Kazuo; Terachi Toshiro; Osamura Robert Yoshiyuki
Variation of alpha-methylacyl-CoA racemase expression in prostate adenocarcinoma cases receiving hormonal therapy.
Human pathology 2006;37(9):1186-92.
2006: Morimoto Daijiro; Yoshida Daizo; Noha Masahiro; Suzuki Masanori; Osamura R Yoshiyuki; Teramoto Akira
Phosphorylation of cAMP response element binding protein (CREB) as a marker of hypoxia in pituitary adenoma.
Journal of neuro-oncology 2006;79(2):143-50.
2006: Sato Haruhiro; Suzuki Yasuhiro; Fukasawa Maki; Yasuda Masanori; Osamura Robert Yoshiyuki
De novo multiple endocrine neoplasia type 2B with noncardiogenic pulmonary edema as the presenting symptom.
Endocrine journal 2006;53(4):523-9.
2006: Muramatsu Toshinari; Shinozuka Takao; Hirasawa Takeshi; Tsukada Hitomi; Maeda Hironobu; Miyamoto Tsuyoshi; Murakami Masaru; Kajiwara Hiroshi; Yasuda Masanori; Osamura R Yoshiyuki; Mikami Mikio
Treatment strategy for recurrent and refractory epithelial ovarian cancer: efficacy of high-dose chemotherapy with hematopoietic stem cell transplantation.
Acta histochemica et cytochemica 2006;39(3):61-7.
2006: Hirabayashi Kenichi; Yasuda Masanori; Osamura R Yoshiyuki; Hirasawa Takeshi; Murakami Masaru
Ovarian nongestational choriocarcinoma mixed with various epithelial malignancies in association with endometriosis.
Gynecologic oncology 2006;102(1):111-7.
2006: Takei Mao; Osamura Robert Yoshiyuki
[Pituitary gangliocytoma]
Nippon rinsho. Japanese journal of clinical medicine 2006;Suppl 1():162-6.
2006: Matsuno Akira; Mizutani Akiko; Takekoshi Susumu; Itoh Johbu; Okinaga Hiroko; Nishina Yuko; Takano Koji; Nagashima Tadashi; Osamura R Yoshiyuki; Teramoto Akira
Analyses of the mechanism of intracellular transport and secretion of pituitary hormone, with an insight of the subcellular localization of pituitary hormone and its mRNA.
Brain tumor pathology 2006;23(1):1-5.
2006: Toyama Ryusuke; Fujimori Toshihiko; Nabeshima Yoko; Itoh Yoshiko; Tsuji Yoshihito; Osamura R Yoshiyuki; Nabeshima Yo-Ichi
Impaired regulation of gonadotropins leads to the atrophy of the female reproductive system in klotho-deficient mice.
Endocrinology 2006;147(1):120-9.
2006: Suzuki Masanori; Minematsu Takeo; Oyama Kenichi; Tahara Shigeyuki; Miyai Shunsuke; Sanno Naoko; Osamura Robert Yoshiyuki; Teramoto Akira
Expression of proliferation markers in human pituitary incidentalomas.
Endocrine pathology 2006;17(3):263-75.
2006: Minematsu Takeo; Suzuki Masanori; Sanno Naoko; Takekoshi Susumu; Teramoto Akira; Osamura R Yoshiyuki
PTTG overexpression is correlated with angiogenesis in human pituitary adenomas.
Endocrine pathology 2006;17(2):143-53.
2006: Ishii Yudo; Suzuki Masanori; Takekoshi Susumu; Egashira Noboru; Yamazaki Michio; Miyai Shunsuke; Sanno Naoko; Teramoto Akira; Osamura Robert Yoshiyuki
Immunonegative "null cell" adenomas and gonadotropin (Gn) subunit (SUs) immunopositive adenomas share frequent expression of multiple transcription factors.
Endocrine pathology 2006;17(1):35-43.
2005: Tsuchiya Kyoichiro; Minami Isao; Tateno Toru; Izumiyama Hajime; Doi Masaru; Nemoto Tetsuo; Mae Sunao; Kasuga Tsutomu; Osamura R Yoshiyuki; Oki Yutaka; Hirata Yukio
Malignant gastric carcinoid causing ectopic ACTH syndrome: discrepancy of plasma ACTH levels measured by different immunoradiometric assays.
Endocrine journal 2005;52(6):743-50.
2005: Kanno Kazuo; Morokuma Yuki; Tateno Toru; Hirono Yuki; Taki Kazuhiro; Osamura R Yoshiyuki; Hirata Yukio
Olfactory neuroblastoma causing ectopic ACTH syndrome.
Endocrine journal 2005;52(6):675-81.
2005: Takumi I; Isayama K; Osamura R Y; Kobayashi S; Teramoto A
Intracisternal neurinoma of the C1 posterior root.
Acta neurochirurgica 2005;147(11):1189-92; discussion 1192.
2005: Miyai Shunsuke; Yoshimura Shinichi; Iwasaki Yasumasa; Takekoshi Susumu; Lloyd Ricardo V; Osamura Robert Yoshiyuki
Induction of GH, PRL, and TSH beta mRNA by transfection of Pit-1 in a human pituitary adenoma-derived cell line.
Cell and tissue research 2005;322(2):269-77.
2005: Iida Tetsuji; Yasuda Masanori; Kajiwara Hiroshi; Minematsu Takeo; Osamura R Yoshiyuki; Itoh Johbu; Inomo Akifumi; Hirasawa Takeshi; Muramatsu Toshinari; Murakami Masaru
Case of uterine cervical carcinosarcoma.
The journal of obstetrics and gynaecology research 2005;31(5):404-8.
2005: Matsuno Akira; Mizutani Akiko; Itoh Johbu; Takekoshi Susumu; Nagashima Tadashi; Okinaga Hiroko; Takano Koji; Osamura R Yoshiyuki
Establishment of stable GH3 cell line expressing enhanced yellow fluorescein protein-growth hormone fusion protein.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(9):1177-80.
2005: Umemura Shinobu; Takekoshi Susumu; Suzuki Yasuhiro; Saitoh Yuki; Tokuda Yutaka; Osamura R Yoshiyuki
Estrogen receptor-negative and human epidermal growth factor receptor 2-negative breast cancer tissue have the highest Ki-67 labeling index and EGFR expression: gene amplification does not contribute to EGFR expression.
Oncology reports 2005;14(2):337-43.
2005: Suzuki Yasuhiro; Tokuda Yutaka; Saito Yuki; Umemura Shinobu; Osamura Robert Yoshiyuki
Clinicopathological correlation between expression of PTHrP receptor and various prognostic factors in breast cancer without axillary lymph node metastasis.
The Tokai journal of experimental and clinical medicine 2005;30(2):127-32.
2005: Tokunaga Masatoshi; Yasuda Masanori; Miyakita Hideshi; Kawamura Yoshiaki; Shoji Sunao; Sasaki Hiroshi; Kono Takuo; Kobayashi Yasuyuki; Shima Masanori; Usui Yukio; Masuda Aiichiro; Kinoshita Hidechika; Ogawa Teppei; Honma Yasuhiko; Osamura R Yoshiyuki; Terachi Toshiro
Screening program of prostate cancer at Tokai University Hospital: characterization of prostate-specific antigen measurement.
The Tokai journal of experimental and clinical medicine 2005;30(2):103-10.
2005: Matsuno Akira; Itoh Johbu; Takekoshi Susumu; Nagashima Tadashi; Osamura R Yoshiyuki
Three-dimensional imaging of the intracellular localization of growth hormone and prolactin and their mRNA using nanocrystal (Quantum dot) and confocal laser scanning microscopy techniques.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(7):833-8.
2005: Tokunaga Masatoshi; Yasuda Masanori; Osamura R Yoshiyuki; Itoh Johbu; Mukai Masaya; Shima Masanori; Usui Yukio; Masuda Aiichiro; Miyakita Hideshi; Terachi Toshiro
Association of neuroendocrine differentiation with neoadjuvant hormone therapy effects in prostatic cancer.
Oncology reports 2005;13(6):1081-7.
2005: Kajiya Hanako; Takekoshi Susumu; Miyai Shunsuke; Ikeda Takako; Kimura Shuichi; Osamura R Yoshiyuki
Dietary soybean enhances Pit-1 dependent pituitary hormone production in iodine deficient rats.
Journal of molecular histology 2005;36(4):265-74.
2005: Yasuda M; Kotajima S; Kajiwara H; Takekoshi S; Osamura R Y; Yoshitake T; Muramatsu T; Miyamoto T; Murakami M; Shinozuka T
Loss of heterozygosity alterations associated with progesterone therapy in endometrial hyperplasia and adenocarcinoma.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2005;15(1):155-62.
2004: Tsukinoki Keiichi; Yasuda Masanori; Mori Yusuke; Asano Shigeyuki; Naito Hiroyuki; Ota Yoshihide; Osamura R Yoshiyuki; Watanabe Yoshihisa
Hepatocyte growth factor and c-Met immunoreactivity are associated with metastasis in high grade salivary gland carcinoma.
Oncology reports 2004;12(5):1017-21.
2004: Yasuda Masanori; Itoh Johbu; Kotajima Shigemi; Itoh Hitoshi; Murakami Masaru; Ogane Naoki; Osamura R Yoshiyuki
Cytologic three-dimensional imaging for the interpretation of staining profiles: application of confocal laser scanning microscopy.
Diagnostic cytopathology 2004;31(3):166-8.
2004: Nagase Eri; Yasuda Masanori; Kajiwara Hiroshi; Osamura R Yoshiyuki; Yoshitake Tomoko; Hirasawa Takeshi; Muramatsu Toshinari; Miyamoto Tsuyoshi; Murakami Masaru; Makino Tsunehisa; Ogawa Teppei
Uterine body cancer mass screening at Tokai University Hospital.
The Tokai journal of experimental and clinical medicine 2004;29(2):43-8.
2004: Yasuda Masanori; Matsui Naruaki; Kajiwara Hiroshi; Osamura R Yoshiyuki; Miyamoto Tsuyoshi; Murakami Masaru; Shinozuka Takao; Itoh Johbu
Malignant transformation of atypical endometrial hyperplasia after progesterone therapy showing germ-cell tumor-like differentiation.
Pathology international 2004;54(6):451-6.
2004: Kuriyama Genshin; Takekoshi Susumu; Tojo Katsuyoshi; Nakai Yoshikatsu; Kuhar Michael J; Osamura R Yoshiyuki
Cocaine- and amphetamine-regulated transcript peptide in the rat anterior pituitary gland is localized in gonadotrophs and suppresses prolactin secretion.
Endocrinology 2004;145(5):2542-50.
2004: Umemura Shinobu; Itoh Johbu; Itoh Hitoshi; Serizawa Akihiko; Saito Yuki; Suzuki Yasuhiro; Tokuda Yutaka; Tajima Tomoo; Osamura R Yoshiyuki
Immunohistochemical evaluation of hormone receptors in breast cancer: which scoring system is suitable for highly sensitive procedures?
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2004;12(1):8-13.
2004: Kijima Hiroshi; Yamazaki Hitoshi; Nakamura Masato; Scanlon Kevin J; Osamura R Yoshiyuki; Ueyama Yoshito
Ribozyme against mutant K-ras mRNA suppresses tumor growth of pancreatic cancer.
International journal of oncology 2004;24(3):559-64.
2004: Takeyama Reiko; Takekoshi Susumu; Nagata Hidetaka; Osamura R Yoshiyuki; Kawana Seiji
Quercetin-induced melanogenesis in a reconstituted three-dimensional human epidermal model.
Journal of molecular histology 2004;35(2):157-65.
2004: Yasuda Masanori; Saito Kaoru; Kobayashi Youichi; Muramatsu Toshinari; Miyamoto Tsuyoshi; Murakami Masaru; Shinozuka Takao; Ishizuka Bunpei; Makino Tsunehisa; Kajiwara Hiroshi; Osamura Robert Yoshiyuki
Serum carbohydrate antigen elevations in endometrial adenocarcinomas: characterization of DU-PAN-2 expression as a tumor marker.
The journal of obstetrics and gynaecology research 2004;30(1):59-64.
2004: Umemura Shinobu; Osamura R Yoshiyuki
Utility of immunohistochemistry in breast cancer practice.
Breast cancer (Tokyo, Japan) 2004;11(4):334-8.
2004: Osamura Robert Yoshiyuki; Egashira Noboru; Miyai Shunsuke; Yamazaki Michio; Takekoshi Susumu; Sanno Naoko; Teramoto Akira
Molecular pathology of the pituitary. Development and functional differentiation of pituitary adenomas.
Frontiers of hormone research 2004;32():20-33.
2003: Tsukinoki Keiichi; Yasuda Masanori; Asano Shigeyuki; Karakida Kazunari; Ota Yoshihide; Osamura R Yoshiyuki; Watanabe Yoshihisa
Association of hepatocyte growth factor expression with salivary gland tumor differentiation.
Pathology international 2003;53(12):815-22.
2003: Dowaki Shoichi; Kijima Hiroshi; Kashiwagi Hiroyuki; Tobita Kosuke; Ohtani Yasuo; Sugio Yoshinori; Sekka Takafumi; Osamura R Yoshiyuki; Imaizumi Toshihide; Makuuchi Hiroyasu
Undifferentiated spindle and giant cell carcinoma of the common bile duct.
The Tokai journal of experimental and clinical medicine 2003;28(3):127-30.
2003: Matsuno Akira; Itoh Johbu; Takekoshi Susumu; Itoh Yoshiko; Ohsugi Yoshitaka; Katayama Haruko; Nagashima Tadashi; Osamura R Yoshiyuki
Dynamics of subcellular organelles, growth hormone, Rab3B, SNAP-25, and syntaxin in rat pituitary cells caused by growth hormone releasing hormone and somatostatin.
Microscopy research and technique 2003;62(3):232-9.
2003: Sekido Yasutomo; Umemura Shinobu; Takekoshi Susumu; Suzuki Yasuhiro; Tokuda Yutaka; Tajima Tomoo; Osamura R Yoshiyuki
Heterogeneous gene alterations in primary breast cancer contribute to discordance between primary and asynchronous metastatic/recurrent sites: HER2 gene amplification and p53 mutation.
International journal of oncology 2003;22(6):1225-32.
2003: Kanehira Tsutomu; Takekoshi Susumu; Nagata Hidetaka; Osamura R Yoshiyuki; Homma Takao
Kinobeon A as a potent tyrosinase inhibitor from cell culture of safflower: in vitro comparisons of kinobeon A with other putative inhibitors.
Planta medica 2003;69(5):457-9.
2003: Umemura Shinobu; Itoh Hitoshi; Ohta Masatoshi; Suzuki Yasuhiro; Kubota Mitsuhiro; Tokuda Yutaka; Tajima Tomoo; Osamura R Yoshiyuki
Immunohistochemical evaluation of hormone receptor for routine practice of breast cancer: highly sensitive procedures significantly contribute to the correlation with biochemical assays.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2003;11(1):62-72.
2003: Inaba Michiko; Umemura Shinobu; Satoh Haruhiro; Abe Yoshifumi; Kurokawa Kiyoshi; Sakai Hideto; Osamura R Yoshiyuki
Expression of RET in follicular cell-derived tumors of the thyroid gland: prevalence and implication of morphological type.
Pathology international 2003;53(3):146-53.
2003: Nakamura Masato; Abe Yoshiyuki; Hatanaka Hiroyuki; Tsutsumi Yutaka; Kijima Hiroshi; Ueyama Yoshito; Inoue Hiroshi; Shimosato Yukio; Osamura R Yoshiyuki
Bronchial carcinoid tumor with gangliocytic- and paraganglionlike differentiation.
Virchows Archiv : an international journal of pathology 2003;442(2):183-5.
2003: Itoh Johbu; Serizawa Akihiko; Kawai Kenji; Ishii Yudo; Teramoto Akira; Osamura Robert Yoshiyuki
Vascular networks and endothelial cells in the rat experimental pituitary glands and in the human pituitary adenomas.
Microscopy research and technique 2003;60(2):231-5.
2003: Sanno Naoko; Teramoto Akira; Osamura R Yoshiyuki; Horvath Eva; Kovacs Kalman; Lloyd Ricardo V; Scheithauer Bernd W
Pathology of pituitary tumors.
Neurosurgery clinics of North America 2003;14(1):25-39, vi.
2003: Osamura Robert Yoshiyuki; Kumaki Nobue; Kajiwara Hiroshi; Egashira Noboru; Miyai Syunsuke; Takekoshi Susumu; Yasuda Masanori; Umemura Shinobu
Endocrine pathology in translational medicine: an overview of current and future prospects.
Endocrine pathology 2003;14(2):117-21.
2003: Tanaka Reika; Umemura Shinobu; Kakuta Takatoshi; Fujisaki Tomotaka; Sakai Hideto; Saitoh Akira; Osamura R Yoshiyuki
Co-expression of parathyroid hormone and chromogranin A in secondary hyperparathyroidism: a functional marker for secretory activity of hyperplastic nodules.
Pathology, research and practice 2003;199(2):93-9.
2002: Tahara Shigeyuki; Kurotani Reiko; Ishii Yudo; Sanno Naoko; Teramoto Akira; Osamura R Yoshiyuki
A case of Cushing's disease caused by pituitary adenoma producing adrenocorticotropic hormone and growth hormone concomitantly: aberrant expression of transcription factors NeuroD1 and Pit-1 as a proposed mechanism.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2002;15(10):1102-5.
2002: Kajiwara Hiroshi; Yasuda Masanori; Yahata Goki; Yamauchi Itaru; Satoh Shinkichi; Hirasawa Takeshi; Osamura R Yoshiyuki
Myxoid leiomyoma of the vulva: a case report.
The Tokai journal of experimental and clinical medicine 2002;27(3):57-64.
2002: Kamoshida S; Satoh Y; Yasuda M; Kajiwara H; Tsukinoki K; Osamura R Yoshiyuki
Immunohistochemical heterogeneity of type 1 blood group antigen expressions in testicular germ cell tumors.
Oncology reports 2002;9(4):845-51.
2002: Kurotani R; Yoshimura S; Iwasaki Y; Inoue K; Teramoto A; Osamura R Y
Exogenous expression of Pit-1 in AtT-20 corticotropic cells induces endogenous growth hormone gene transcription.
The Journal of endocrinology 2002;172(3):477-87.
2002: Tsuda Hitoshi; Sasano Hironobu; Akiyama Futoshi; Kurosumi Masafumi; Hasegawa Tadashi; Osamura R Yoshiyuki; Sakamoto Goi
Evaluation of interobserver agreement in scoring immunohistochemical results of HER-2/neu (c-erbB-2) expression detected by HercepTest, Nichirei polyclonal antibody, CB11 and TAB250 in breast carcinoma.
Pathology international 2002;52(2):126-34.
2002: Umeoka Katsuya; Sanno Naoko; Osamura R Yoshiyuki; Teramoto Akira
Expression of GATA-2 in human pituitary adenomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2002;15(1):11-7.
2002: Inaba Michiko; Umemura Shinobu; Satoh Haruhiro; Ichikawa Yasuko; Abe Yosifumi; Kirokawa Kiyoshi; Sakai Hideto; Osamura R Yoshiyuki
Papillary thyroid carcinoma with fibromatosis-like stroma: a report of two cases.
Endocrine pathology 2002;13(3):219-25.
2002: Kumaki Nobue; Kajiwara Hiroshi; Kameyama Kaori; DeLellis Ronald A; Asa Sylvia L; Osamura R Yoshiyuki; Takami Hiroshi
Prediction of malignant behavior of pheochromocytomas and paragangliomas using immunohistochemical techniques.
Endocrine pathology 2002;13(2):149-56.
2001: Itoh J; Kawai K; Serizawa A; Yamamoto Y; Ogawa K; Matsuno A; Watanabe K; Osamura R Y
Three-dimensional imaging of hormone-secreting cells and their microvessel environment in estrogen-induced prolactinoma of the rat pituitary gland by confocal laser scanning microscopy.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2001;9(4):364-70.
2001: Umeoka K; Sanno N; Oyama K; Tahara S; Kurotani R; Ikuyama S; Nakashima M; Watanabe T; Osamura R Y; Teramoto A
Immunohistochemical analysis of RCAS1 in human pituitary adenomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2001;14(12):1232-6.
2001: Umemura S; Iwasaka T; Kakimoto K; Takahashi A; Koizumi H; Miyakawa Y; Kurotani R; Osamura R Y
Expression of prolactin gene in spontaneous mammary tumors in aging Fischer 344 rats.
Endocrine journal 2001;48(5):597-602.
2001: Kono M; Nagata H; Umemura S; Kawana S; Osamura R Y
In situ expression of corticotropin-releasing hormone (CRH) and proopiomelanocortin (POMC) genes in human skin.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(12):2297-9.
2001: Sanno N; Teramoto A; Osamura R Y
Thyrotropin-secreting pituitary adenomas. Clinical and biological heterogeneity and current treatment.
Journal of neuro-oncology 2001;54(2):179-86.
2001: Umemura S; Iwasaka T; Osamura R Y
Expression of chromogranin/secretogranin mRNA in spontaneous mammary tumors in aging Fischer-344 rats.
Pathology international 2001;51(9):667-70.
2001: Sone M; Nagata H; Takekoshi S; Osamura R Y
Expression and localization of leptin receptor in the normal rat pituitary gland.
Cell and tissue research 2001;305(3):351-6.
2001: Oyama K; Sanno N; Teramoto A; Osamura R Y
Expression of neuro D1 in human normal pituitaries and pituitary adenomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2001;14(9):892-9.
2001: Kurotani R; Yasuda M; Oyama K; Egashira N; Sugaya M; Teramoto A; Osamura R Y
Expression of interleukin-6, interleukin-6 receptor (gp80), and the receptor's signal-transducing subunit (gp130) in human normal pituitary glands and pituitary adenomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2001;14(8):791-7.
2001: Kim K; Arai K; Sanno N; Osamura R Y; Teramoto A; Shibasaki T
Ghrelin and growth hormone (GH) secretagogue receptor (GHSR) mRNA expression in human pituitary adenomas.
Clinical endocrinology 2001;54(6):759-68.
2001: Matsuno A; Ogino Y; Katayama H; Osamura R Y; Nagashima T
Identification of a silent pituitary somatotropic adenoma based on a paradoxic response of growth hormone on a thyrotropin-releasing hormone or gonadotropin-releasing hormone provocation test.
American journal of obstetrics and gynecology 2001;184(3):286-8.
2001: Sone M; Osamura R Y
Leptin and the pituitary.
Pituitary 2001;4(1-2):15-23.
2001: Sanno N; Tahara S; Kurotani R; Matsuno A; Teramoto A; Osamura R Y
Cytochemical and molecular biological aspects of the pituitary and pituitary adenomas--cell differentiation and transcription factors.
Progress in histochemistry and cytochemistry 2001;36(4):263-99.
2001: Umemura S; Sakamoto G; Sasano H; Tsuda H; Akiyama F; Kurosumi M; Tokuda Y; Watanabe T; Toi M; Hasegawa T; Osamura R Y
Evaluation of HER2 status: for the treatment of metastatic breast cancers by humanized anti-HER2 Monoclonal antibody (trastuzumab) (Pathological committee for optimal use of trastuzumab).
Breast cancer (Tokyo, Japan) 2001;8(4):316-20.
2001: Tokuda Y; Suzuki Y; Ohta M; Saito Y; Kubota M; Tajima T; Umemura S; Osamura R Y
Compassionate use of humanized anti-HER2/neu protein, trastuzumab for metastatic breast cancer in Japan.
Breast cancer (Tokyo, Japan) 2001;8(4):310-5.
2001: Satoh F; Umemura S; Yasuda M; Osamura R Y
Neuroendocrine marker expression in thyroid epithelial tumors.
Endocrine pathology 2001;12(3):291-9.
2001: Komatsubara K; Tahara S; Umeoka K; Sanno N; Teramoto A; Osamura R Y
Immunohistochemical analysis of p27 (Kip1) in human pituitary glands and in various types of pituitary adenomas.
Endocrine pathology 2001;12(2):181-8.
2001: Matsuno A; Itoh J; Itoh Y; Osamura R Y; Katayama H; Nagashima T
Histopathological analyses of silent pituitary somatotroph adenomas using immunohistochemistry, in situ hybridization and confocal laser scanning microscopic observation.
Pathology, research and practice 2001;197(1):13-20.
2000: Tahara S; Kurotani R; Sanno N; Takumi I; Yoshimura S; Osamura R Y; Teramoto A
Expression of pituitary homeo box 1 (Ptx1) in human non-neoplastic pituitaries and pituitary adenomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2000;13(10):1097-108.
2000: Yasuda M; Okabe T; Itoh J; Takekoshi S; Hasegawa H; Nagata H; Osamura R Y; Watanabe K
Differentiation of necrotic cell death with or without lysosomal activation: application of acute liver injury models induced by carbon tetrachloride (CCL4) and dimethylnitrosamine (DMN).
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2000;48(10):1331-9.
2000: Sanno N; Teramoto A; Osamura R Y
Long-term surgical outcome in 16 patients with thyrotropin pituitary adenoma.
Journal of neurosurgery 2000;93(2):194-200.
2000: Tamaki T; Takumi I; Kitamura T; Osamura R Y; Teramoto A
Pituitary stone--case report.
Neurologia medico-chirurgica 2000;40(7):383-6.
2000: Matsuno A; Katakami H; Nagashima T; Teramoto A; Osamura R Y; Kirino T
Growth hormone-releasing hormone expression in pituitary somatotroph adenomas, studied by immunohistochemistry and in situ hybridization using catalyzed signal amplification system.
Human pathology 2000;31(7):789-94.
2000: Kamoshida S; Ogane N; Yasuda M; Muramatsu T; Bessho T; Kajiwara H; Osamura R Y
Immunohistochemical study of type-1 blood antigen expressions in thyroid tumors: the significance for papillary carcinomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2000;13(7):736-41.
2000: Osamura R Y; Itoh Y; Matsuno A
Applications of plastic embedding to electron microscopic immunocytochemistry and in situ hybridization in observations of production and secretion of peptide hormones.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2000;48(7):885-91.
2000: Jin H S; Umemura S; Iwasaka T; Osamura R Y
Alterations of myoepithelial cells in the rat mammary gland during pregnancy, lactation and involution, and after estradiol treatment.
Pathology international 2000;50(5):384-91.
2000: Itoh J; Kawai K; Serizawa A; Yasumura K; Ogawa K; Osamura R Y
A new approach to three-dimensional reconstructed imaging of hormone-secreting cells and their microvessel environments in rat pituitary glands by confocal laser scanning microscopy.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2000;48(4):569-78.
2000: Osamura R Y; Tahara S; Kurotani R; Sanno N; Matsuno A; Teramoto A
Contributions of immunohistochemistry and in situ hybridization to the functional analysis of pituitary adenomas.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2000;48(4):445-58.
2000: Matsuno A; Ogino Y; Itoh J; Osamura R Y; Nagashima T
Detection of a silent pituitary somatotroph adenoma in a patient with amenorrhea and/or galactorrhea: paradoxical response of GH in TRH or GnRH provocation test.
Endocrine journal 2000;47 Suppl():S105-9.
2000: Itoh J; Yasumura K; Takeshita T; Ishikawa H; Kobayashi H; Ogawa K; Kawai K; Serizawa A; Osamura R Y
Three-dimensional imaging of tumor angiogenesis.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2000;22(1):85-90.
2000: Satoh F; Umemura S; Osamura R Y
Immunohistochemical analysis of GCDFP-15 and GCDFP-24 in mammary and non-mammary tissue.
Breast cancer (Tokyo, Japan) 2000;7(1):49-55.
2000: Suzuki Y; Tokuda Y; Okumura A; Saito Y; Ohta M; Kubota M; Makuuchi H; Tajima T; Umemura S; Osamura R Y
Three cases of malignant lymphoma of the breast.
Japanese journal of clinical oncology 2000;30(1):33-6.
2000: Matsuno A; Nagashima T; Ohsugi Y; Utsunomiya H; Takekoshi S; Munakata S; Nagao K; Osamura R Y; Watanabe K
Electron microscopic observation of intracellular expression of mRNA and its protein product: technical review on ultrastructural in situ hybridization and its combination with immunohistochemistry.
Histology and histopathology 2000;15(1):261-8.
1999: Kurotani R; Tahara S; Sanno N; Teramoto A; Mellon P L; Inoue K; Yoshimura S; Osamura R Y
Expression of Ptx1 in the adult rat pituitary glands and pituitary cell lines: hormone-secreting cells and folliculo-stellate cells.
Cell and tissue research 1999;298(1):55-61.
1999: Matsuno A; Katakami H; Sanno N; Ogino Y; Osamura R Y; Matsukura S; Shimizu N; Nagashima T
Pituitary somatotroph adenoma producing growth hormone (GH)-releasing hormone (GHRH) with an elevated plasma GHRH concentration: a model case for autocrine and paracrine regulation of GH secretion by GHRH.
The Journal of clinical endocrinology and metabolism 1999;84(9):3241-7.
1999: Onda H; Yasuda M; Serizawa A; Osamura R Y; Kawamura N
Clinical outcome in localized renal cell carcinomas related to immunoexpression of proliferating cell nuclear antigen, Ki-67 antigen, and tumor size.
Oncology reports 1999;6(5):1039-43.
1999: Tahara S; Sanno N; Teramoto A; Osamura R Y
Expression of Rab3, a Ras-related GTP-binding protein, in human nontumorous pituitaries and pituitary adenomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1999;12(6):627-34.
1999: Osamura R Y; Tahara S; Komatsubara K; Itoh Y; Kajiwara H; Kurotani R; Sanno N; Teramoto A
Pit-1 positive alpha-subunit positive nonfunctioning human pituitary adenomas: a dedifferentiated GH cell lineage?
Pituitary 1999;1(3-4):269-71.
1999: Kajiwara H; Itoh Y; Itoh J; Yasuda M; Osamura R Y
Immunohistochemical expressions of prohormone convertase (PC)1/3 and PC2 in carcinoids of various organs.
The Tokai journal of experimental and clinical medicine 1999;24(1):13-20.
1999: Matsuno A; Sanno N; Tahara S; Teramoto A; Osamura R Y; Wada H; Murakami M; Tanaka H; Nagashima T
Silent somatotroph adenoma, detected by catalyzed signal amplification and non-radioisotopic in situ hybridization.
Endocrine journal 1999;46 Suppl():S81-4.
1999: Sugiyama M; Takumi I; Node Y; Sanno N; Teramoto A; Osamura R Y
Neurohypophyseal germinoma with prolactinoma. Case illustration.
Journal of neurosurgery 1999;90(1):170.
1998: Matsuno A; Nagashima T; Takekoshi S; Utsunomiya H; Sanno N; Osamura R Y; Watanabe K; Tamura A; Teramoto A
Ultrastructural simultaneous identification of growth hormone and its messenger ribonucleic acid.
Endocrine journal 1998;45 Suppl():S101-4.
1998: Satoh F; Umemura S; Itoh H; Miyajima Y; Tokuda Y; Tajima T; Osamura R Y
Fine needle aspiration cytology of glycogen-rich clear cell carcinoma of the breast. A case report.
Acta cytologica 1998;42(2):413-8.
1998: Takumi I; Steiner D F; Sanno N; Teramoto A; Osamura R Y
Localization of prohormone convertases 1/3 and 2 in the human pituitary gland and pituitary adenomas: analysis by immunohistochemistry, immunoelectron microscopy, and laser scanning microscopy.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1998;11(3):232-8.
1998: Matsuno A; Ohsugi Y; Utsunomiya H; Takekoshi S; Munakata S; Nagao K; Osamura R Y; Tamura A; Nagashima T
An improved ultrastructural double-staining method for rat growth hormone and its mRNA using LR White resin: a technical note.
The Histochemical journal 1998;30(2):105-9.
1998: Yasuda M; Itoh J; Hirasawa T; Hirazono K; Shinozuka T; Sasano H; Osamura R Y
Serous borderline ovarian tumor with functioning stroma in a postmenopausal woman: immunohistochemical analysis of steroidogenic pathway.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 1998;17(1):75-8.
1998: Sanno N; Shimura T; Takumi I; Tahara S; Node Y; Aihara K; Osamura R Y; Teramoto A
An adult case of cerebral primitive neuroectodermal tumour.
Acta neurochirurgica 1998;140(5):445-6.
1998: Sanno N; Teramoto A; Sugiyama M; Matsuno A; Takumi I; Tahara S; Osamura R Y
Expression of Pit-1 mRNA and activin/inhibin subunits in clinically nonfunctioning pituitary adenomas. In situ hybridization and immunohistochemical analysis.
Hormone research 1998;50(1):11-7.
1997: Itoh J; Sanno N; Matsuno A; Itoh Y; Watanabe K; Osamura R Y
Application of confocal laser scanning microscopy (CLSM) to visualize prolactin (PRL) and PRL mRNA in the normal and estrogen-treated rat pituitary glands using non-fluorescent probes.
Microscopy research and technique 1997;39(2):157-67.
1997: Sanno N; Itoh J; Teramoto A; Itoh Y; Hori S; Osamura R Y
Immunohistochemical detection of human natural killer cell like immunoreactivity in human pituitary adenomas, using monoclonal antibody NK-1.
Journal of neuro-oncology 1997;35(1):29-38.
1997: Hirasawa T; Yasuda M; Muramatsu T; Itoh H; Shinozuka T; Makino T; Tsutsumi Y; Osamura R Y
Cytologic study of ascites and the endometrium in ovarian carcinoma. Clinical significance.
Acta cytologica 1997;41(5):1451-5.
1997: Ohta M; Tokuda Y; Suzuki Y; Kuge S; Okumura A; Kubota M; Tajima T; Osamura R Y; Mitomi T
A case of multiple endocrine neoplasia type 2B.
Japanese journal of clinical oncology 1997;27(4):268-73.
1997: Sanno N; Teramoto A; Osamura R Y; Genka S; Katakami H; Jin L; Lloyd R V; Kovacs K
A growth hormone-releasing hormone-producing pancreatic islet cell tumor metastasized to the pituitary is associated with pituitary somatotroph hyperplasia and acromegaly.
The Journal of clinical endocrinology and metabolism 1997;82(8):2731-7.
1997: Matsuno A; Takekoshi S; Sanno N; Utsunomiya H; Ohsugi Y; Saito N; Kanemitsu H; Tamura A; Nagashima T; Osamura R Y; Watanabe K
Modulation of protein kinases and microtubule-associated proteins and changes in ultrastructure in female rat pituitary cells: effects of estrogen and bromocriptine.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1997;45(6):805-13.
1997: Akashi K; Yasuda M; Suto R; Fukuda H; Itoh J; Tsutsumi Y; Osamura R Y
A case of epithelioid hemangioendothelioma associated with an artery.
The Tokai journal of experimental and clinical medicine 1997;22(2):65-9.
1997: Ohta M; Tokuda Y; Kuge S; Okumura A; Tanaka M; Kubota M; Tajima T; Akatsuka A; Osamura R Y; Tamaoki N; Mitomi T
A case of angiosarcoma of the breast.
Japanese journal of clinical oncology 1997;27(2):91-4.
1997: Mochizuki S; Umemura S; Tokuda Y; Tajima T; Mitomi T; Osamura R Y
A study of 46 cumulative breast cancer autopsy cases.
The Tokai journal of experimental and clinical medicine 1997;22(1):19-25.
1997: Osamura R Y; Yasuda O; Kawakami T; Itoh Y; Inada K; Kakudo K
Immunoelectron microscopic demonstration of regulated pathway for calcitonin and constitutive pathway for carcinoembryonic antigen in the same cells of human medullary carcinomas of thyroid glands.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1997;10(1):7-11.
1996: Matsuno A; Utsunomiya H; Ohsugi Y; Takekoshi S; Sanno N; Osamura R Y; Nagao K; Tamura A; Nagashima T
Simultaneous ultrastructural identification of growth hormone and its messenger ribonucleic acid using combined immunohistochemistry and non-radioisotopic in situ hybridization: a technical note.
The Histochemical journal 1996;28(10):703-7.
1996: Itoh Y; Tanaka S; Takekoshi S; Itoh J; Osamura R Y
Prohormone convertases (PC1/3 and PC2) in rat and human pancreas and islet cell tumors: subcellular immunohistochemical analysis.
Pathology international 1996;46(10):726-37.
1996: Sanno N; Teramoto A; Sugiyama M; Itoh Y; Osamura R Y
Application of catalyzed signal amplification in immunodetection of gonadotropin subunits in clinically nonfunctioning pituitary adenomas.
American journal of clinical pathology 1996;106(1):16-21.
1996: Tsutsumi Y; Osamura R Y; Makuuchi H
Intermediate lymphocytic lymphoma massively involving the gastrointestinal tract.
Pathology international 1996;46(5):380-3.
1996: Sanno N; Teramoto A; Matsuno A; Takekoshi S; Itoh J; Osamura R Y
Expression of Pit-1 and estrogen receptor messenger RNA in prolactin-producing pituitary adenomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1996;9(5):526-33.
1996: Umemura S; Osamura R Y; Tsutsumi Y
'Magentosis' in human lactating breast: a mode of cell death accumulating single-stranded DNA stretches or breaks.
Pathology international 1996;46(2):122-9.
1996: Umemura S; Osamura R Y; Tsutsumi Y
Cell renewal and functional morphology of human lactating breast: presentation of a new mode of cell death ('magentosis') characterized by nuclear periodic acid-Schiff reactivity.
Pathology international 1996;46(2):105-21.
1996: Umemura S; Yasuda M; Osamura R Y; Kawarada Y; Sugiyama T; Tsutsumi Y
Enhancement of TdT-mediated dUTP-biotin nick end-labeling (TUNEL) method using mung bean nuclease, a single-stranded DNA digestion enzyme.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1996;44(2):125-32.
1996: Sanno N; Teramoto A; Matsuno A; Osamura R Y
Expression of human Pit-1 product in the human pituitary and pituitary adenomas. Immunohistochemical studies using an antibody against synthetic human Pit-1 product.
Archives of pathology & laboratory medicine 1996;120(1):73-7.
1996: Sanno N; Teramoto A; Osamura R Y
Clinical and cytofunctional classification of pituitary adenomas: proposal of a new classification.
Acta neurochirurgica 1996;138(10):1186-92.
1996: Sanno N; Teramoto A; Matsuno A; Itoh J; Takekoshi S; Osamura R Y
In situ hybridization analysis of Pit-1 mRNA and hormonal production in human pituitary adenomas.
Acta neuropathologica 1996;91(3):263-8.
1995: Sanno N; Teramoto A; Matsuno A; Takekoshi S; Osamura R Y
GH and PRL gene expression by nonradioisotopic in situ hybridization in TSH-secreting pituitary adenomas.
The Journal of clinical endocrinology and metabolism 1995;80(8):2518-22.
1995: Vilor M; Tsutsumi Y; Osamura R Y; Tokunaga N; Soeda J; Ohta M; Nakazaki H; Shibayama Y; Ueno F
Small cell neuroendocrine carcinoma of the rectum.
Pathology international 1995;45(8):605-9.
1995: Murakoshi M; Osamura R Y; Yoshimura S; Watanabe K
Immunolocalization of glutathione-peroxidase (GSH-PO) in human adrenal gland--studies on adrenocortical adenomas associated with primary aldosteronism and Cushing's syndrome.
The Tokai journal of experimental and clinical medicine 1995;20(2):89-97.
1995: Umemura S; Oda K; Utsunomiya H; Sanno N; Itoh J; Katakami H; Osamura R Y
Immunohistochemical characterization of "hyperplasia-adenoma sequence" in the pituitaries of transgenic mice expressing a human growth hormone-releasing factor gene.
The Tokai journal of experimental and clinical medicine 1995;20(2):71-9.
1995: Matsuno A; Ohsugi Y; Utsunomiya H; Takekoshi S; Sanno N; Osamura R Y; Watanabe K; Teramoto A; Kirino T
Changes in the ultrastructural distribution of prolactin and growth hormone mRNAs in pituitary cells of female rats after estrogen and bromocriptine treatment, studied using in situ hybridization with biotinylated oligonucleotide probes.
Histochemistry and cell biology 1995;104(1):37-45.
1995: Matsuno A; Teramoto A; Takekoshi S; Sanno N; Osamura R Y; Kirino T
Expression of plurihormonal mRNAs in somatotrophic adenomas detected using a nonisotopic in situ hybridization method: comparison with lactotrophic adenomas.
Human pathology 1995;26(3):272-9.
1995: Umemura S; Kawai K; Osamura R Y; Tsutsumi Y
Antigen retrieval for bcl-2 protein in formalin-fixed, paraffin-embedded sections.
Pathology international 1995;45(2):103-7.
1995: Akamatsu M; Hori S; Tsutsumi Y; Osamura R Y; Ohkido M
Ubiquitinated cytokeratin inclusions in lichen amyloidosus: an immunohistochemical analysis.
Pathology international 1995;45(2):116-22.
1995: Tang X; Hori S; Osamura R Y; Tsutsumi Y
Reticular crypt epithelium and intra-epithelial lymphoid cells in the hyperplastic human palatine tonsil: an immunohistochemical analysis.
Pathology international 1995;45(1):34-44.
1994: Sanno N; Teramoto A; Matsuno A; Inada K; Itoh J; Osamura R Y
Clinical and immunohistochemical studies on TSH-secreting pituitary adenoma: its multihormonality and expression of Pit-1.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1994;7(9):893-9.
1994: Matsuno A; Teramoto A; Yamada S; Kitanaka S; Tanaka T; Sanno N; Osamura R Y; Kirino T
Gigantism in sibling unrelated to multiple endocrine neoplasia: case report.
Neurosurgery 1994;35(5):952-5; discussion 955-6.
1994: Matsuno A; Teramoto A; Takekoshi S; Utsunomiya H; Ohsugi Y; Kishikawa S; Osamura R Y; Kirino T; Lloyd R V
Application of biotinylated oligonucleotide probes to the detection of pituitary hormone mRNA using northern blot analysis, in situ hybridization at the light- and electron-microscope levels.
The Histochemical journal 1994;26(10):771-7.
1994: Matsuno A; Ohsugi Y; Utsunomiya H; Takekoshi S; Osamura R Y; Watanabe K; Teramoto A; Kirino T
Ultrastructural distribution of growth hormone and prolactin mRNAs in normal rat pituitary cells: a comparison between preembedding and postembedding methods.
Histochemistry 1994;102(4):265-70.
1993: Osamura R Y; Oda K; Utsunomiya H; Inada K; Umemura S; Shibuya M; Katakami H; Voss J W; Mayo K E; Rosenfeld M G
Immunohistochemical expression of PIT-1 protein in pituitary glands of human GRF transgenic mice: its relationship with hormonal expressions.
Endocrine journal 1993;40(1):133-9.
1992: Inada K; Oda K; Utsunomiya H; Itoh J; Osamura R Y
Immunohistochemical analysis of GH-producing adenomas--with special emphasis on plurihormonality of individual tumor cells by double staining.
The Tokai journal of experimental and clinical medicine 1992;17(5-6):213-22.
1992: Onoda N; Kamezu Y; Takagi S; Shinohara Y; Osamura R Y
An autopsy case of invasive pituitary adenoma (prolactinoma) with rapid fatal clinical course due to streptococcal meningitis.
Acta pathologica japonica 1992;42(11):832-6.
1992: Osamura R Y; Murakoshi M; Inada R; Horiuchi T; Watanabe K
Biological aspects of pituitary tumors induced by synthetic salmon calcitonin (TZ-CT) in Sprague-Dawley rats. Immunohistochemical and ultrastructural studies.
Acta pathologica japonica 1992;42(6):401-7.
1991: Tsutsumi Y; Kawai K; Hori S; Osamura R Y
Ultrastructural visualization of human papillomavirus DNA in verrucous and precancerous squamous lesions.
Acta pathologica japonica 1991;41(10):757-62.
1991: Osamura R Y
Application of preembedding immunohistochemistry in the study of adenohypophysial plurihormonality.
Journal of electron microscopy technique 1991;19(1):57-63.
1991: Tauchi K; Tsutsumi Y; Hori S; Yoshimura S; Osamura R Y; Watanabe K
Expression of heat shock protein 70 and c-myc protein in human breast cancer: an immunohistochemical study.
Japanese journal of clinical oncology 1991;21(4):256-63.
1991: Osamura R Y
Processing of proopiomelanocortin (POMC) approached by immunoelectron microscopy pre-embedding method.
Pathology, research and practice 1991;187(5):543-5.
1991: Osamura R Y; Suemizu Y; Yoshimura S; Hori S; Inada K; Watanabe K; Nakai Y; Imura H
Secretory pathways and processing of human proopiomelanocortin (POMC) using transformed mouse cultured fibroblasts (L cells) and AtT20 cells by human POMC gene--preembedding immunoelectron microscopic studies.
Peptides 1991;12(3):503-7.
1990: Onoda N; Tsutsumi Y; Kakudo K; Ozawa A; Niizuma K; Ohkido M; Osamura R Y
Pigmented dermatofibrosarcoma protuberans (Bednár tumor). An autopsy case with systemic metastasis.
Acta pathologica japonica 1990;40(12):935-40.
1990: Katoh Y; Shimamura K; Kakudo K; Osamura R Y; Tamaoki N
An autopsy case of a cystic variant of thymic carcinoma mimicking a thymic cyst.
Virchows Archiv. A, Pathological anatomy and histopathology 1990;417(1):85-7.
1989: Saitoh A; Tsutsumi Y; Osamura R Y; Watanabe K
Sclerosing stromal tumor of the ovary. Immunohistochemical and electron-microscopic demonstration of smooth-muscle differentiation.
Archives of pathology & laboratory medicine 1989;113(4):372-6.
1989: Tauchi K; Hori S; Itoh H; Osamura R Y; Tokuda Y; Tajima T
Immunohistochemical studies on oncogene products (c-erbB-2, EGFR, c-myc) and estrogen receptor in benign and malignant breast lesions. With special reference to their prognostic significance in carcinoma.
Virchows Archiv. A, Pathological anatomy and histopathology 1989;416(1):65-73.
1988: Osamura R Y; Chrétien M; Marcinkiewicz M
Ultrastructural localization of secretory granule constituent chromogranin and 7 B 2.
Pathology, research and practice 1988;183(5):617-9.
1988: Osamura R Y
Immunoelectron microscopic observation of prolactin (PRL) in human PRL secreting pituitary adenomas and non-neoplastic pituitary PRL cells.
Pathology, research and practice 1988;183(5):584-6.
1988: Osamura R Y
Immunoelectron microscopic demonstration of glycoprotein subunits in the FSH producing pituitary adenomas.
Pathology, research and practice 1988;183(5):606-9.
1988: Osamura R Y
Immunoelectron microscopic studies of GH and alpha subunit in GH secreting pituitary adenomas.
Pathology, research and practice 1988;183(5):569-71.
1988: Osamura R Y; Watanabe K
Immunohistochemical studies of human FSH producing pituitary adenomas.
Virchows Archiv. A, Pathological anatomy and histopathology 1988;413(1):61-8.

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