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Melissa Osborne

Research Profile

Living Beings

Disorders

Type 1 Diabetes Mellitus

Anatomy

Physiology

Chemicals & Drugs

Procedures

Lymphocyte Depletion

Genes & Molecular Sequences

Quantitative Trait Loci

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Publications

TOP 3
David V Serreze; Caroline-Morgane Choisy-Rossi; Alexandra E Grier; Thomas M Holl; Harold D Chapman; J Reed Gahagan; Melissa A Osborne; Weidong Zhang; Benjamin L King; Aaron Clifford Brown; Derry C Roopenian; Michele P Marron
Through regulation of TCR expression levels, an Idd7 region gene(s) interactively contributes to the impaired thymic deletion of autoreactive diabetogenic CD8+ T cells in nonobese diabetic mice.
Yi-Guang Chen; Pablo Alejandro Silveira; Melissa A Osborne; Harold D Chapman; David V Serreze
Cellular expression requirements for inhibition of type 1 diabetes by a dominantly protective major histocompatibility complex haplotype.
David V Serreze; Melissa A Osborne; Yi-Guang Chen; Harold D Chapman; Todd Pearson; Michael A Brehm; Dale L Greiner
Partial versus full allogeneic hemopoietic chimerization is a preferential means to inhibit type 1 diabetes as the latter induces generalized immunosuppression.

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All Publications

2008: David V Serreze; Caroline-Morgane Choisy-Rossi; Alexandra E Grier; Thomas M Holl; Harold D Chapman; J Reed Gahagan; Melissa A Osborne; Weidong Zhang; Benjamin L King; Aaron Clifford Brown; Derry C Roopenian; Michele P Marron
Through regulation of TCR expression levels, an Idd7 region gene(s) interactively contributes to the impaired thymic deletion of autoreactive diabetogenic CD8+ T cells in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):3250-9.
2007: Yi-Guang Chen; Pablo Alejandro Silveira; Melissa A Osborne; Harold D Chapman; David V Serreze
Cellular expression requirements for inhibition of type 1 diabetes by a dominantly protective major histocompatibility complex haplotype.
Diabetes 2007;56(2):424-30.
2006: David V Serreze; Melissa A Osborne; Yi-Guang Chen; Harold D Chapman; Todd Pearson; Michael A Brehm; Dale L Greiner
Partial versus full allogeneic hemopoietic chimerization is a preferential means to inhibit type 1 diabetes as the latter induces generalized immunosuppression.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):6675-84.
2006: Yi-Guang Chen; Jing Chen; Melissa A Osborne; Harold D Chapman; Gurdyal S Besra; Steven A Porcelli; Edward H Leiter; S Brian Wilson; David V Serreze
CD38 is required for the peripheral survival of immunotolerogenic CD4+ invariant NK T cells in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(5):2939-47.

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