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Philip Osdoby

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Patricia Collin-Osdoby; Philip Osdoby
RANKL-mediated osteoclast formation from murine RAW 264.7 cells.
Patricia Collin-Osdoby; Philip Osdoby
Isolation and culture of primary chicken osteoclasts.
Thomas E Uveges; Patricia Collin-Osdoby; Wayne A Cabral; Felicia Ledgard; Leah Goldberg; Clemens Bergwitz; Antonella Forlino; Philip Osdoby; Gloria A Gronowicz; Joan C Marini
Cellular mechanism of decreased bone in Brtl mouse model of OI: imbalance of decreased osteoblast function and increased osteoclasts and their precursors.

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All Publications

2012: Patricia Collin-Osdoby; Philip Osdoby
RANKL-mediated osteoclast formation from murine RAW 264.7 cells.
Methods in molecular biology (Clifton, N.J.) 2012;816():187-202.
2012: Patricia Collin-Osdoby; Philip Osdoby
Isolation and culture of primary chicken osteoclasts.
Methods in molecular biology (Clifton, N.J.) 2012;816():119-43.
2008: Thomas E Uveges; Patricia Collin-Osdoby; Wayne A Cabral; Felicia Ledgard; Leah Goldberg; Clemens Bergwitz; Antonella Forlino; Philip Osdoby; Gloria A Gronowicz; Joan C Marini
Cellular mechanism of decreased bone in Brtl mouse model of OI: imbalance of decreased osteoblast function and increased osteoclasts and their precursors.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2008;23(12):1983-94.
2006: Hong Zheng; Xuefeng Yu; Patricia Collin-Osdoby; Philip Osdoby
RANKL stimulates inducible nitric-oxide synthase expression and nitric oxide production in developing osteoclasts. An autocrine negative feedback mechanism triggered by RANKL-induced interferon-beta via NF-kappaB that restrains osteoclastogenesis and bone resorption.
The Journal of biological chemistry 2006;281(23):15809-20.
2006: Libby Kindle; Linda Rothe; Michael Kriss; Philip Osdoby; Patricia Collin-Osdoby
Human microvascular endothelial cell activation by IL-1 and TNF-alpha stimulates the adhesion and transendothelial migration of circulating human CD14+ monocytes that develop with RANKL into functional osteoclasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(2):193-206.
2005: Laura H Saltman; Amjad Javed; John Ribadeneyra; Sadiq Hussain; Daniel Young; Philip Osdoby; Alla Amcheslavsky; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian; Zvi Bar-Shavit
Organization of transcriptional regulatory machinery in osteoclast nuclei: compartmentalization of Runx1.
Journal of cellular physiology 2005;204(3):871-80.
2005: Lorinda M Wright; William Maloney; Xuefeng Yu; Libby Kindle; Patricia Collin-Osdoby; Philip Osdoby
Stromal cell-derived factor-1 binding to its chemokine receptor CXCR4 on precursor cells promotes the chemotactic recruitment, development and survival of human osteoclasts.
Bone 2005;36(5):840-53.
2004: Xuefeng Yu; Yuefang Huang; Patricia Collin-Osdoby; Philip Osdoby
CCR1 chemokines promote the chemotactic recruitment, RANKL development, and motility of osteoclasts and are induced by inflammatory cytokines in osteoblasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(12):2065-77.
2003: Xuefeng Yu; Yuefang Huang; Patricia Collin-Osdoby; Philip Osdoby
Stromal cell-derived factor-1 (SDF-1) recruits osteoclast precursors by inducing chemotaxis, matrix metalloproteinase-9 (MMP-9) activity, and collagen transmigration.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(8):1404-18.
2003: Xuefeng Yu; Patricia Collin-Osdoby; Philip Osdoby
SDF-1 increases recruitment of osteoclast precursors by upregulation of matrix metalloproteinase-9 activity.
Connective tissue research 2003;44 Suppl 1():79-84.
2003: Patricia Collin-Osdoby; Xuefeng Yu; Hong Zheng; Philip Osdoby
RANKL-mediated osteoclast formation from murine RAW 264.7 cells.
Methods in molecular medicine 2003;80():153-66.
2003: Patricia Collin-Osdoby; Fred Anderson; Philip Osdoby
Primary isolation and culture of chicken osteoclasts.
Methods in molecular medicine 2003;80():65-88.
2002: Gloria Elena Benito; María Luz Sánchez; Javier del Pino-Montes; José Julián Calvo; Pablo Menéndez; María Antonia García-Marcos; Philip Osdoby; Alberto Orfao
A new cytometric method for the immunophenotypic characterization of bone-derived human osteoclasts.
Cytometry 2002;50(5):261-6.
2002: Patricia Collin-Osdoby; Linda Rothe; Simon Bekker; Fred Anderson; Yuefang Huang; Philip Osdoby
Basic fibroblast growth factor stimulates osteoclast recruitment, development, and bone pit resorption in association with angiogenesis in vivo on the chick chorioallantoic membrane and activates isolated avian osteoclast resorption in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(10):1859-71.
2002: Jeff P Gorski; Fu-Tong Liu; Antonio Artigues; Leonardo F Castagna; Philip Osdoby
New alternatively spliced form of galectin-3, a member of the beta-galactoside-binding animal lectin family, contains a predicted transmembrane-spanning domain and a leucine zipper motif.
The Journal of biological chemistry 2002;277(21):18840-8.
2001: Patricia Collin-Osdoby; Linda Rothe; Fred Anderson; M Nelson; W Maloney; Philip Osdoby
Receptor activator of NF-kappa B and osteoprotegerin expression by human microvascular endothelial cells, regulation by inflammatory cytokines, and role in human osteoclastogenesis.
The Journal of biological chemistry 2001;276(23):20659-72.
2000: Patricia Collin-Osdoby; Linda Rothe; S Bekker; Fred Anderson; Philip Osdoby
Decreased nitric oxide levels stimulate osteoclastogenesis and bone resorption both in vitro and in vivo on the chick chorioallantoic membrane in association with neoangiogenesis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(3):474-88.
1999: T Sunyer; J Lewis; Patricia Collin-Osdoby; Philip Osdoby
Estrogen's bone-protective effects may involve differential IL-1 receptor regulation in human osteoclast-like cells.
The Journal of clinical investigation 1999;103(10):1409-18.
1998: Linda Rothe; Patricia Collin-Osdoby; Y Chen; T Sunyer; L Chaudhary; A Tsay; Steven R Goldring; Louis V Avioli; Philip Osdoby
Human osteoclasts and osteoclast-like cells synthesize and release high basal and inflammatory stimulated levels of the potent chemokine interleukin-8.
Endocrinology 1998;139(10):4353-63.
1998: Patricia Collin-Osdoby; L Li; Linda Rothe; Fred Anderson; D Kirsch; M J Oursler; Philip Osdoby
Inhibition of avian osteoclast bone resorption by monoclonal antibody 121F: a mechanism involving the osteoclast free radical system.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(1):67-78.
1997: T Sunyer; Linda Rothe; D Kirsch; X Jiang; Fred Anderson; Philip Osdoby; Patricia Collin-Osdoby
Ca2+ or phorbol ester but not inflammatory stimuli elevate inducible nitric oxide synthase messenger ribonucleic acid and nitric oxide (NO) release in avian osteoclasts: autocrine NO mediates Ca2+-inhibited bone resorption.
Endocrinology 1997;138(5):2148-62.
1997: Z Khalkhali-Ellis; Patricia Collin-Osdoby; L Li; Maria Luisa Brandi; Philip Osdoby
A human homolog of the 150 kD avian osteoclast membrane antigen related to superoxide dismutase and essential for bone resorption is induced by developmental agents and opposed by estrogen in FLG 29.1 cells.
Calcified tissue international 1997;60(2):187-93.
1996: T Sunyer; Linda Rothe; X Jiang; Philip Osdoby; Patricia Collin-Osdoby
Proinflammatory agents, IL-8 and IL-10, upregulate inducible nitric oxide synthase expression and nitric oxide production in avian osteoclast-like cells.
Journal of cellular biochemistry 1996;60(4):469-83.
1995: N Hernando; M Bartkiewicz; Patricia Collin-Osdoby; Philip Osdoby; Roland Baron
Alternative splicing generates a second isoform of the catalytic A subunit of the vacuolar H(+)-ATPase.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(13):6087-91.
1995: Janice E Berry; Martha J Somerman; Z Khalkhali-Ellis; Philip Osdoby; robert simpson
HL-60 cell differentiation and osteopontin expression.
Annals of the New York Academy of Sciences 1995;760():302-4.
1995: Patricia Collin-Osdoby; G Allen Nickols; Philip Osdoby
Bone cell function, regulation, and communication: a role for nitric oxide.
Journal of cellular biochemistry 1995;57(3):399-408.
1995: Martha J Somerman; Janice E Berry; Z Khalkhali-Ellis; Philip Osdoby; robert simpson
Enhanced expression of alpha v integrin subunit and osteopontin during differentiation of HL-60 cells along the monocytic pathway.
Experimental cell research 1995;216(2):335-41.
1995: Patricia Collin-Osdoby; Merry Jo Oursler; Linda Rothe; D Webber; Fred Anderson; Philip Osdoby
Osteoclast 121F antigen expression during osteoblast conditioned medium induction of osteoclast-like cells in vitro: relationship to calcitonin responsiveness, tartrate resistant acid phosphatase levels, and bone resorptive activity.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(1):45-58.
1994: R J Galvin; J W Cullison; L V Avioli; Philip Osdoby
Influence of osteoclasts and osteoclast-like cells on osteoblast alkaline phosphatase activity and collagen synthesis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(8):1167-78.
1994: T P Kasten; Patricia Collin-Osdoby; N Patel; Philip Osdoby; M Krukowski; TP Misko; Steven L Settle; M G Currie; G Allen Nickols
Potentiation of osteoclast bone-resorption activity by inhibition of nitric oxide synthase.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):3569-73.
1993: Merry Jo Oursler; L Pederson; J Pyfferoen; Philip Osdoby; L Fitzpatrick; Thomas C Spelsberg
Estrogen modulation of avian osteoclast lysosomal gene expression.
Endocrinology 1993;132(3):1373-80.
1992: E M Greenfield; J I Alvarez; E A McLaurine; Merry Jo Oursler; HC Blair; Philip Osdoby; Steven L Teitelbaum; F Patrick Ross
Avian osteoblast conditioned media stimulate bone resorption by targeting multinucleating osteoclast precursors.
Calcified tissue international 1992;51(4):317-23.
1992: B Groessner-Schreiber; M Krukowski; C Lyons; Philip Osdoby
Osteoclast recruitment in response to human bone matrix is age related.
Mechanisms of ageing and development 1992;62(2):143-54.
1991: Patricia Collin-Osdoby; Merry Jo Oursler; D Webber; Philip Osdoby
Osteoclast-specific monoclonal antibodies coupled to magnetic beads provide a rapid and efficient method of purifying avian osteoclasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1991;6(12):1353-65.
1991: Merry Jo Oursler; Philip Osdoby; J Pyfferoen; Lawrence B. Riggs; Thomas C Spelsberg
Avian osteoclasts as estrogen target cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(15):6613-7.
1991: Merry Jo Oursler; Patricia Collin-Osdoby; L Li; E Schmitt; Philip Osdoby
Evidence for an immunological and functional relationship between superoxide dismutase and a high molecular weight osteoclast plasma membrane glycoprotein.
Journal of cellular biochemistry 1991;46(4):331-44.
1991: Merry Jo Oursler; L Li; Philip Osdoby
Purification and characterization of an osteoclast membrane glycoprotein with homology to manganese superoxide dismutase.
Journal of cellular biochemistry 1991;46(3):219-33.
1991: B Groessner-Schreiber; M Krukowski; D Hertweck; Philip Osdoby
Osteoclast formation is related to bone matrix age.
Calcified tissue international 1991;48(5):335-40.
1991: Merry Jo Oursler; Patricia Collin-Osdoby; Fred Anderson; L Li; D Webber; Philip Osdoby
Isolation of avian osteoclasts: improved techniques to preferentially purify viable cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1991;6(4):375-85.
1990: M Krukowski; R A Shively; Philip Osdoby; B L Eppley
Stimulation of craniofacial and intramedullary bone formation by negatively charged beads.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 1990;48(5):468-75.
1990: D Webber; Philip Osdoby; P Hauschka; M Krukowski
Correlation of an osteoclast antigen and ruffled border on giant cells formed in response to resorbable substrates.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(4):401-10.
1988: Merry Jo Oursler; Philip Osdoby
Osteoclast development in marrow cultured in calvaria-conditioned media.
Developmental biology 1988;127(1):170-8.
1988: M Krukowski; DJ Simmons; A Summerfield; Philip Osdoby
Charged beads: generation of bone and giant cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1988;3(2):165-71.
1988: Philip Osdoby; Merry Jo Oursler; T Salino-Hugg; M Krukowski
Osteoclast development: the cell surface and the bone environment.
Ciba Foundation symposium 1988;136():108-24.
1987: Philip Osdoby; M Krukowski; Merry Jo Oursler; T Salino-Hugg
The origin, development and regulation of osteoclasts.
BioEssays : news and reviews in molecular, cellular and developmental biology 1987;7(1):30-4.
1986: Philip Osdoby; Merry Jo Oursler; Fred Anderson
The osteoblast and osteoclast cytodifferentiation.
Progress in clinical and biological research 1986;217B():409-14.
1985: Merry Jo Oursler; L V Bell; B Clevinger; Philip Osdoby
Identification of osteoclast-specific monoclonal antibodies.
The Journal of cell biology 1985;100(5):1592-600.