FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Pamela Osenkowski

Research Profile

Chemicals & Drugs

Phenomena

Catalysis

Physiology

Living Beings

Concepts & Ideas

Anatomy

Procedures

Biotinylation

Co-author Network

Publications

TOP 3
Omar Quintero-Monzon; Christina A Cappello; Marty A Fernandez; Amanda J Krzysiak; Morgan M Martin; Pamela Osenkowski; Michael S Wolfe
Dissociation between the processivity and total activity of γ-secretase: implications for the mechanism of Alzheimer's disease-causing presenilin mutations.
Pamela Osenkowski; Huilin Li; Wenjuan Ye; Dongyang Li; Lorene Aeschbach; Patrick C Fraering; Michael S Wolfe; Dennis J Selkoe; Huilin Li
Cryoelectron microscopy structure of purified gamma-secretase at 12 A resolution.
Pamela Osenkowski; Wenjuan Ye; Rong Wang; Michael S Wolfe; Dennis J Selkoe
Direct and potent regulation of gamma-secretase by its lipid microenvironment.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Pamela Osenkowski (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2011: Omar Quintero-Monzon; Christina A Cappello; Marty A Fernandez; Amanda J Krzysiak; Morgan M Martin; Pamela Osenkowski; Michael S Wolfe
Dissociation between the processivity and total activity of γ-secretase: implications for the mechanism of Alzheimer's disease-causing presenilin mutations.
Biochemistry 2011;50(42):9023-35.
2009: Pamela Osenkowski; Huilin Li; Wenjuan Ye; Dongyang Li; Lorene Aeschbach; Patrick C Fraering; Michael S Wolfe; Dennis J Selkoe; Huilin Li
Cryoelectron microscopy structure of purified gamma-secretase at 12 A resolution.
Journal of molecular biology 2009;385(2):642-52.
2008: Pamela Osenkowski; Wenjuan Ye; Rong Wang; Michael S Wolfe; Dennis J Selkoe
Direct and potent regulation of gamma-secretase by its lipid microenvironment.
The Journal of biological chemistry 2008;283(33):22529-40.
2008: Jin-Ah Cho; Pamela Osenkowski; Huiren Zhao; Seaho Kim; Marta Toth; Kristina Cole; Amro Aboukameel; Allen Saliganan; Lucia Schuger; R Daniel Bonfil; Rafael Fridman
The inactive 44-kDa processed form of membrane type 1 matrix metalloproteinase (MT1-MMP) enhances proteolytic activity via regulation of endocytosis of active MT1-MMP.
The Journal of biological chemistry 2008;283(25):17391-405.
2008: Matthias Cacquevel; Lorene Aeschbach; Pamela Osenkowski; Dongyang Li; Wenjuan Ye; Michael S Wolfe; Huilin Li; Dennis J Selkoe; Patrick C Fraering
Rapid purification of active gamma-secretase, an intramembrane protease implicated in Alzheimer's disease.
Journal of neurochemistry 2008;104(1):210-20.
2007: R Daniel Bonfil; Zhong Dong; J Carlos Trindade Filho; Aaron Sabbota; Pamela Osenkowski; Sanaa M Nabha; Hamilto Yamamoto; Sreenivasa R Chinni; Huiren Zhao; Shahriar Mobashery; Robert L Vessella; Rafael Fridman; Michael L Cher
Prostate cancer-associated membrane type 1-matrix metalloproteinase: a pivotal role in bone response and intraosseous tumor growth.
The American journal of pathology 2007;170(6):2100-11.
2007: Heather M McClung; Stacey L Thomas; Pamela Osenkowski; Marta Toth; Priya Menon; Avraham Raz; Rafael Fridman; Sandra Rempel
SPARC upregulates MT1-MMP expression, MMP-2 activation, and the secretion and cleavage of galectin-3 in U87MG glioma cells.
Neuroscience letters 2007;419(2):172-7.
2005: Pamela Osenkowski; Samy O Meroueh; Dumitru Pavel; Shahriar Mobashery; Rafael Fridman
Mutational and structural analyses of the hinge region of membrane type 1-matrix metalloproteinase and enzyme processing.
The Journal of biological chemistry 2005;280(28):26160-8.
2005: Marta Toth; Pamela Osenkowski; Dusan Hesek; Stephen Brown; Samy O Meroueh; Wael A Sakr; Shahriar Mobashery; Rafael Fridman
Cleavage at the stem region releases an active ectodomain of the membrane type 1 matrix metalloproteinase.
The Biochemical journal 2005;387(Pt 2):497-506.
2004: Pamela Osenkowski; Marta Toth; Rafael Fridman
Processing, shedding, and endocytosis of membrane type 1-matrix metalloproteinase (MT1-MMP).
Journal of cellular physiology 2004;200(1):2-10.
2004: Huiren Zhao; Maria Margarida Bernardo; Pamela Osenkowski; anjum sohail; Duanqing Pei; Hideaki Nagase; Masahide Kashiwagi; Paul D Soloway; Yves A DeClerck; Rafael Fridman
Differential inhibition of membrane type 3 (MT3)-matrix metalloproteinase (MMP) and MT1-MMP by tissue inhibitor of metalloproteinase (TIMP)-2 and TIMP-3 rgulates pro-MMP-2 activation.
The Journal of biological chemistry 2004;279(10):8592-601.
2004: R Daniel Bonfil; Pamela Osenkowski; Rafael Fridman; Michael L Cher
Matrix metalloproteinaes and bone metastasis.
Cancer treatment and research 2004;118():173-95.
2002: Marta Toth; Sonia Hernandez-Barrantes; Pamela Osenkowski; Maria Margarida Bernardo; David C Gervasi; Yoichiro Shimura; Oussama Meroueh; Lakshmi P Kotra; Beatriz G Gálvez; Alicia G Arroyo; Shahriar Mobashery; Rafael Fridman
Complex pattern of membrane type 1 matrix metalloproteinase shedding. Regulation by autocatalytic cells surface inactivation of active enzyme.
The Journal of biological chemistry 2002;277(29):26340-50.