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Stephen Osgood

Research Profile

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Chemicals & Drugs

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Ribosomes

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Molecular Structure

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Publications

TOP 3
Punit P Seth; Alycia Miyaji; Elizabeth A Jefferson; Kristin A Sannes-Lowery; Stephen A Osgood; Stephanie Propp; Ray Ranken; Christian Massire; Rangarajan Sampath; David J Ecker; Eric E Swayze; Richard H Griffey
SAR by MS: discovery of a new class of RNA-binding small molecules for the hepatitis C virus: internal ribosome entry site IIA subdomain.
Punit P Seth; Ray Ranken; Dale E Robinson; Stephen A Osgood; Lisa M Risen; Elizabeth L Rodgers; Michael T Migawa; Elizabeth A Jefferson; Eric E Swayze
Aryl urea analogs with broad-spectrum antibacterial activity.
Elizabeth A Jefferson; Punit P Seth; Dale E Robinson; Dana K Winter; Alycia Miyaji; Lisa M Risen; Stephen A Osgood; Myra Bertrand; Eric E Swayze
Optimizing the antibacterial activity of a lead structure discovered by "SAR by MS" technology.

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All Publications

2005: Punit P Seth; Alycia Miyaji; Elizabeth A Jefferson; Kristin A Sannes-Lowery; Stephen A Osgood; Stephanie Propp; Ray Ranken; Christian Massire; Rangarajan Sampath; David J Ecker; Eric E Swayze; Richard H Griffey
SAR by MS: discovery of a new class of RNA-binding small molecules for the hepatitis C virus: internal ribosome entry site IIA subdomain.
Journal of medicinal chemistry 2005;48(23):7099-102.
2004: Punit P Seth; Ray Ranken; Dale E Robinson; Stephen A Osgood; Lisa M Risen; Elizabeth L Rodgers; Michael T Migawa; Elizabeth A Jefferson; Eric E Swayze
Aryl urea analogs with broad-spectrum antibacterial activity.
Bioorganic & medicinal chemistry letters 2004;14(22):5569-72.
2004: Elizabeth A Jefferson; Punit P Seth; Dale E Robinson; Dana K Winter; Alycia Miyaji; Lisa M Risen; Stephen A Osgood; Myra Bertrand; Eric E Swayze
Optimizing the antibacterial activity of a lead structure discovered by "SAR by MS" technology.
Bioorganic & medicinal chemistry letters 2004;14(21):5257-61.
2004: Elizabeth A Jefferson; Punit P Seth; Dale E Robinson; Dana K Winter; Alycia Miyaji; Stephen A Osgood; Eric E Swayze; Lisa M Risen
Biaryl guanidine inhibitors of in vitro HCV-IRES activity.
Bioorganic & medicinal chemistry letters 2004;14(20):5139-43.
2003: Punit P Seth; Elizabeth A Jefferson; Lisa M Risen; Stephen A Osgood
Identification of 2-aminobenzimidazole dimers as antibacterial agents.
Bioorganic & medicinal chemistry letters 2003;13(10):1669-72.
2003: Elizabeth A Jefferson; Eric E Swayze; Stephen A Osgood; Alycia Miyaji; Lisa M Risen; Lawrence B Blyn
Antibacterial activity of quinolone-macrocycle conjugates.
Bioorganic & medicinal chemistry letters 2003;13(10):1635-8.
2002: Eric E Swayze; Elizabeth A Jefferson; Kristin A Sannes-Lowery; Lawrence B Blyn; Lisa M Risen; Satoshi Arakawa; Stephen A Osgood; Steven A Hofstadler; Richard H Griffey
SAR by MS: a ligand based technique for drug lead discovery against structured RNA targets.
Journal of medicinal chemistry 2002;45(18):3816-9.
2002: Elizabeth A Jefferson; Satoshi Arakawa; Lawrence B Blyn; Alycia Miyaji; Stephen A Osgood; Ray Ranken; Lisa M Risen; Eric E Swayze
New inhibitors of bacterial protein synthesis from a combinatorial library of macrocycles.
Journal of medicinal chemistry 2002;45(16):3430-9.
1999: PW Davis; Stephen A Osgood
A new method for introducing amidate linkages in oligonucleotides using phosphoramidite chemistry.
Bioorganic & medicinal chemistry letters 1999;9(18):2691-2.
1998: PW Davis; Stephen A Osgood; N Hébert; Kelly Sprankle; Eric E Swayze
Solid-phase synthesis of a library of functionalized aminodiol scaffolds.
Biotechnology and bioengineering 1998;61(3):143-54.