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Mitsuo Oshimura

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TOP 3
Yuwna Yakura; Hiroyuki Takeya; Takefumi Doi; Chie Ishihara; Yasuhiro Kazuki; Norio Komatsu; Hajime Kurosaki; Yoshiaki Okada; Mitsuo Oshimura
An induced pluripotent stem cell-mediated and integration-free factor VIII expression system.
Yasuhiro Kazuki; Kaoru Kobayashi; Kinya Kubo; Yoshimi Kuroiwa; Sumio Ohtsuki; Takeshi Oshima; Satoshi Abe; Sasitorn Aueviriyavit; Kan Chiba; Hidetoshi Hoshiya; Naoyo Kajitani; Hiroki Kawakami; Naoto Senda; S Takehara; Masato Takiguchi; Tetsuya Terasaki; Kazuma Tomizuka; Yasuko Tsukazaki; Mitsuo Oshimura
Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans.
Yoshihisa Watanabe; Mitsuo Oshimura; Toshimichi Ikemura; Yasuhiro Kazuki; Masato Maekawa
Replication timing in a single human chromosome 11 transferred into the Chinese hamster ovary (CHO) cell line.

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All Publications

2013: Yuwna Yakura; Hiroyuki Takeya; Takefumi Doi; Chie Ishihara; Yasuhiro Kazuki; Norio Komatsu; Hajime Kurosaki; Yoshiaki Okada; Mitsuo Oshimura
An induced pluripotent stem cell-mediated and integration-free factor VIII expression system.
Biochemical and biophysical research communications 2013;431(2):336-41.
2013: Yasuhiro Kazuki; Kaoru Kobayashi; Kinya Kubo; Yoshimi Kuroiwa; Sumio Ohtsuki; Takeshi Oshima; Satoshi Abe; Sasitorn Aueviriyavit; Kan Chiba; Hidetoshi Hoshiya; Naoyo Kajitani; Hiroki Kawakami; Naoto Senda; S Takehara; Masato Takiguchi; Tetsuya Terasaki; Kazuma Tomizuka; Yasuko Tsukazaki; Mitsuo Oshimura
Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans.
Human molecular genetics 2013;22(3):578-92.
2012: Yoshihisa Watanabe; Mitsuo Oshimura; Toshimichi Ikemura; Yasuhiro Kazuki; Masato Maekawa
Replication timing in a single human chromosome 11 transferred into the Chinese hamster ovary (CHO) cell line.
Gene 2012;510(1):1-6.
2012: Natsuko Imaoka; Atsushi Kambe; Hideki Kamitani; Shinsuke Kato; Masanori Kurimoto; Shoichi Nagai; Eisaku Ohama; Futoshi Okada; Mitsuhiko Osaki; Junya Fukuoka; Masaharu Hiratsuka; Takashi Watanabe; Mitsuo Oshimura
Prognostic significance of sirtuin 2 protein nuclear localization in glioma: an immunohistochemical study.
Oncology reports 2012;28(3):923-30.
2012: Tomoko Nakanishi; Haruka Oda; Mitsuo Oshimura; Mika Aoki; Yasuhiro Kazuki; Kazuo Kokubun; Atsumi Soma; Makoto Taniguchi; Kenzo Sato
Bioluminescence imaging of bone formation using hairless osteocalcin-luciferase transgenic mice.
Bone 2012;51(3):369-75.
2012: Francesco Saverio Tedesco; Rossana Tonlorenzi; Yvan Torrente; Federica Ungaro; Stefania Antonini; Valentina Artusi; Sara Benedetti; Roberto Bottinelli; Vania Broccoli; Giorgia Calderazzi; Ornella Cappellari; Marco Cassano; Mattia F M Gerli; Hidetoshi Hoshiya; Emanuela Longa; Marina Mora; Mitsuo Oshimura; Laura Perani; Martina Ragazzi; Maurilio Sampaolesi; Peter Schneiderat; Benedikt Schoser; Enrico Tagliafico; Giulio Cossu
Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy.
Science translational medicine 2012;4(140):140ra89.
2012: Masanori Takehashi; Masako Tada; Takashi Tada; Mito Kanatsu-Shinohara; Yasuhiro Kazuki; Hiroko Morimoto; Mitsuo Oshimura; Takashi Shinohara
Hybridization of testis-derived stem cells with somatic cells and embryonic stem cells in mice.
Biology of reproduction 2012;86(6):178.
2012: Masayuki Itoh; Yu-ichi Goto; Shuhei Ide; Shigeru Noguchi; Mitsuo Oshimura; Akihiro Otsuki; Toshikuni Sasaoka; Candice G T Tahimic; Akihiro Kurimasa
Methyl CpG-binding protein isoform MeCP2_e2 is dispensable for Rett syndrome phenotypes but essential for embryo viability and placenta development.
The Journal of biological chemistry 2012;287(17):13859-67.
2012: Mitsuo Oshimura; Yasuhiro Kazuki; Narumi Uno
[Challenge toward gene-therapy using iPS cells for Duchenne muscular dystrophy].
Rinshō shinkeigaku = Clinical neurology 2012;52(11):1139-42.
2011: Yasuhiro Kazuki; Mitsuo Oshimura
[Toward gene and cell therapy using human artificial chromosome].
Nihon rinsho. Japanese journal of clinical medicine 2011;69(12):2142-7.
2011: Minoru Kakeda; Yasuhiro Kazuki; Anri Masuya; Hiroki Matsuno; Keiko Nagata; Satoshi Nishikawa; Akiyo Okazaki; Mitsuhiko Osaki; Kanako Osawa; Mitsuo Oshimura; Akiko Sano; Shingo Shitara; Toshihiro Hata; Masaharu Hiratsuka; Shun Wako; Kazuma Tomizuka
A new chromosome 14-based human artificial chromosome (HAC) vector system for efficient transgene expression in human primary cells.
Biochemical and biophysical research communications 2011;415(3):439-44.
2011: Hajime Kurosaki; Jun Mimuro; Masaharu Hiratsuka; Yuichi Iida; Natsuko Imaoka; Chie Ishihara; Yasuhiro Kazuki; Youichi Sakata; Hiroyuki Takeya; Narumi Uno; Yuwna Yakura; Mitsuo Oshimura
Integration-free and stable expression of FVIII using a human artificial chromosome.
Journal of human genetics 2011;56(10):727-33.
2011: Makiko Meguro-Horike; Mitsuo Oshimura; Weston Powell; Diane I Schroeder; Dag H Yasui; Janine M LaSalle; Shin-ichi Horike
Neuron-specific impairment of inter-chromosomal pairing and transcription in a novel model of human 15q-duplication syndrome.
Human molecular genetics 2011;20(19):3798-810.
2011: Yasuhiro Kazuki; Mitsuo Oshimura
Human artificial chromosomes for gene delivery and the development of animal models.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(9):1591-601.
2011: Francesco Saverio Tedesco; Rossana Tonlorenzi; Yvan Torrente; Stefania Antonini; Sara Benedetti; Libera Berghella; Roberto Bottinelli; Giuseppe D'Antona; Mattia F M Gerli; Hidetoshi Hoshiya; Yasuhiro Kazuki; Graziella Messina; Mitsuo Oshimura; Giulio Cossu
Stem cell-mediated transfer of a human artificial chromosome ameliorates muscular dystrophy.
Science translational medicine 2011;3(96):96ra78.
2011: Chi Chiu Wang; Yasuhiro Kazuki; Mitsuo Oshimura; Kazuho Ikeo; Takashi Gojobori
Gene dosage imbalance of human chromosome 21 in mouse embryonic stem cells differentiating to neurons.
Gene 2011;481(2):93-101.
2011: Mitsuhiko Osaki; Fumitaka Takeshita; Yui Sugimoto; Nobuyoshi Kosaka; Yusuke Yamamoto; Yusuke Yoshioka; Eisuke Kobayashi; Tesshi Yamada; Akira Kawai; Toshiaki Inoue; Hisao Ito; Mitsuo Oshimura; Takahiro Ochiya
MicroRNA-143 regulates human osteosarcoma metastasis by regulating matrix metalloprotease-13 expression.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(6):1123-30.
2011: Dong-Lai Qi; Takahito Ohhira; Chikako Fujisaki; Toshiaki Inoue; Tsutomu Ohta; Mitsuhiko Osaki; Eriko Ohshiro; Tomomi Seko; Shinsuke Aoki; Mitsuo Oshimura; Hiroyuki Kugoh
Identification of PITX1 as a TERT suppressor gene located on human chromosome 5.
Molecular and cellular biology 2011;31(8):1624-36.
2011: Yasuhiro Kazuki; Hidetoshi Hoshiya; M Takiguchi; Satoshi Abe; Y Iida; Mitsuhiko Osaki; Motonobu Katoh; Masaharu Hiratsuka; Yasuaki Shirayoshi; K Hiramatsu; E Ueno; N Kajitani; T Yoshino; K Kazuki; C Ishihara; S Takehara; S Tsuji; F Ejima; A Toyoda; Y Sakaki; Vladimir Larionov; Natalay Kouprina; Mitsuo Oshimura
Refined human artificial chromosome vectors for gene therapy and animal transgenesis.
Gene therapy 2011;18(4):384-93.
2011: Masaharu Hiratsuka; Natsuko Imaoka; Motonobu Katoh; Kanako Kazuki; Yasuhiro Kazuki; Hajime Kurosaki; Masato Nakagawa; Mitsuhiko Osaki; Kana Ueda; Etsuya Ueno; Narumi Uno; Shinya Yamanaka; Yutaro Akakura; Mitsuo Oshimura
Integration-free iPS cells engineered using human artificial chromosome vectors.
PloS one 2011;6(10):e25961.
2011: Hisakatsu Nawata; Mitsuo Oshimura; Yoshiya Shimada; Keizo Tano; Kazuhiro Daino; Genro Kashino; Hiroyuki Kugoh; Masami Watanabe
Dysregulation of gene expression in the artificial human trisomy cells of chromosome 8 associated with transformed cell phenotypes.
PloS one 2011;6(9):e25319.
2011: Mayu Yasunaga; Yasuhiro Kazuki; Tomoko Nakanishi; Mitsuhiko Osaki; Mitsuo Oshimura; Nao Oumi; Kenzo Sato
Establishment and characterization of a transgenic mouse model for in vivo imaging of Bmp4 expression in the pancreas.
PloS one 2011;6(9):e24956.
2011: Shigeyuki Yamaguchi; Yasuhiro Kazuki; Yuji Nakayama; Eiji Nanba; Mitsuo Oshimura; Tetsuya Ohbayashi
A method for producing transgenic cells using a multi-integrase system on a human artificial chromosome vector.
PloS one 2011;6(2):e17267.
2011: Yanze Li; Haruka Matsumori; Yuji Nakayama; Mitsuhiko Osaki; Hirotada Kojima; Akihiro Kurimasa; Hisao Ito; Seiichi Mori; Motonobu Katoh; Mitsuo Oshimura; Toshiaki Inoue
SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis.
Genes to cells : devoted to molecular & cellular mechanisms 2011;16(1):34-45.
2011: Yasuomi Kunimoto; Seiji Nakano; Hideyuki Kataoka; Yutaka Shimada; Mitsuo Oshimura; Hiroya Kitano
Deleted in Esophageal Cancer 1(DEC1) is down-regulated and contributes to migration in head and neck squamous cell carcinoma cell lines.
ORL; journal for oto-rhino-laryngology and its related specialties 2011;73(1):17-23.
2010: Yuichi Iida; Jung-Hyun Kim; Yasuhiro Kazuki; Hidetoshi Hoshiya; Masato Takiguchi; Masahiro Hayashi; Indri Erliandri; Hee-Sheung Lee; Alex Samoshkin; Hiroshi Masumoto; William C Earnshaw; Natalay Kouprina; Vladimir Larionov; Mitsuo Oshimura
Human artificial chromosome with a conditional centromere for gene delivery and gene expression.
DNA research : an international journal for rapid publication of reports on genes and genomes 2010;17(5):293-301.
2010: Shigeyuki Yamaguchi; Tetsuya Ohbayashi; Yasuhiro Kazuki; Mitsuo Oshimura
[Advantages and applications of human artificial chromosome vector].
Seikagaku. The Journal of Japanese Biochemical Society 2010;82(9):846-52.
2010: Dong-Lai Qi; Takahito Ohhira; Mitsuo Oshimura; Hiroyuki Kugoh
Human chromosome 5 carries a transcriptional regulator of human telomerase reverse transcriptase (hTERT).
Biochemical and biophysical research communications 2010;398(4):695-701.
2010: Mitsuhiko Osaki; Aiko Inaba; Kei Nishikawa; Yui Sugimoto; Kohei Shomori; Toshiaki Inoue; Mitsuo Oshimura; Hisao Ito
Cysteine-rich protein 61 suppresses cell invasion via down-regulation of matrix metalloproteinase-7 expression in the human gastric carcinoma cell line MKN-45.
Molecular medicine reports 2010;3(4):711-5.
2010: Yusuke Takahashi; Saori Tsuji; Yasuhiro Kazuki; Makoto Noguchi; Ichiro Arifuku; Yukihiro Umebayashi; Tomoko Nakanishi; Mitsuo Oshimura; Kenzo Sato
Development of evaluation system for bioactive substances using human artificial chromosome-mediated osteocalcin gene expression.
Journal of biochemistry 2010;148(1):29-34.
2010: Yusuke Kinoshita; Hideki Kamitani; Mahabub Hasan Mamun; Brian Wasita; Yasuhiro Kazuki; Masaharu Hiratsuka; Mitsuo Oshimura; Takashi Watanabe
A gene delivery system with a human artificial chromosome vector based on migration of mesenchymal stem cells towards human glioblastoma HTB14 cells.
Neurological research 2010;32(4):429-37.
2010: Yasuhiro Kazuki; Masaharu Hiratsuka; Masato Takiguchi; Mitsuhiko Osaki; Naoyo Kajitani; Hidetoshi Hoshiya; Kei Hiramatsu; Toko Yoshino; Kanako Kazuki; Chie Ishihara; S Takehara; Katsumi Higaki; Masato Nakagawa; Kazutoshi Takahashi; Shinya Yamanaka; Mitsuo Oshimura
Complete genetic correction of ips cells from Duchenne muscular dystrophy.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(2):386-93.
2010: Satoshi Abe; Hiromi Tanaka; Tomomi Notsu; Shin-ichi Horike; Chikako Fujisaki; Dong-Lai Qi; Takahito Ohhira; David Gilley; Mitsuo Oshimura; Hiroyuki Kugoh
Localization of an hTERT repressor region on human chromosome 3p21.3 using chromosome engineering.
Genome integrity 2010;1(1):6.
2010: Motonobu Katoh; Yasuhiro Kazuki; Kanako Kazuki; Naoyo Kajitani; Masato Takiguchi; Yuji Nakayama; Takafumi Nakamura; Mitsuo Oshimura
Exploitation of the interaction of measles virus fusogenic envelope proteins with the surface receptor CD46 on human cells for microcell-mediated chromosome transfer.
BMC biotechnology 2010;10():37.
2009: Akiko Kashiwagi; Hajime Kurosaki; Hong Luo; Hiroshi Yamamoto; Mitsuo Oshimura; Toshiyuki Shibahara
Effects of Tritrichomonas muris on the mouse intestine: a proteomic analysis.
Experimental animals / Japanese Association for Laboratory Animal Science 2009;58(5):537-42.
2009: Jiyoung Lee; Mito Kanatsu-Shinohara; Hiroko Morimoto; Yasuhiro Kazuki; Seiji Takashima; Mitsuo Oshimura; Shinya Toyokuni; Takashi Shinohara
Genetic reconstruction of mouse spermatogonial stem cell self-renewal in vitro by Ras-cyclin D2 activation.
Cell stem cell 2009;5(1):76-86.
2009: Kentaro Ariyoshi; Keiji Suzuki; Makoto Goto; Mitsuo Oshimura; Kanji Ishizaki; Masami Watanabe; Seiji Kodama
Introduction of a normal human chromosome 8 corrects abnormal phenotypes of Werner syndrome cells immortalized by expressing an hTERT gene.
Journal of radiation research 2009;50(3):253-9.
2009: Toshiaki Inoue; Yuji Nakayama; Hidetoshi Yamada; Yanze C Li; Shigeyuki Yamaguchi; Mitsuhiko Osaki; Akihiro Kurimasa; Masaharu Hiratsuka; Motonobu Katoh; Mitsuo Oshimura
SIRT2 downregulation confers resistance to microtubule inhibitors by prolonging chronic mitotic arrest.
Cell cycle (Georgetown, Tex.) 2009;8(8):1279-91.
2009: Shinjirou Kawazoe; Nobuhito Ikeda; Kengo Miki; Masayuki Shibuya; Kumi Morikawa; Seiji Nakano; Mitsuo Oshimura; Ichiro Hisatome; Yasuaki Shirayoshi
Extrinsic factors derived from mouse embryonal carcinoma cell lines maintain pluripotency of mouse embryonic stem cells through a novel signal pathway.
Development, growth & differentiation 2009;51(2):81-93.
2009: Hidetoshi Hoshiya; Yasuhiro Kazuki; Satoshi Abe; Masato Takiguchi; Naoyo Kajitani; Yoshinori Watanabe; Toko Yoshino; Yasuaki Shirayoshi; Katsumi Higaki; Graziella Messina; Giulio Cossu; Mitsuo Oshimura
A highly stable and nonintegrated human artificial chromosome (HAC) containing the 2.4 Mb entire human dystrophin gene.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(2):309-17.
2009: Yoshiteru Kai; Chi Chiu Wang; Satoshi Kishigami; Yasuhiro Kazuki; Satoshi Abe; Masato Takiguchi; Yasuaki Shirayoshi; Toshiaki Inoue; Hisao Ito; Teruhiko Wakayama; Mitsuo Oshimura
Enhanced apoptosis during early neuronal differentiation in mouse ES cells with autosomal imbalance.
Cell research 2009;19(2):247-58.
2009: K Murakami; T Ohhira; E Oshiro; D Qi; Mitsuo Oshimura; Hiroyuki Kugoh
Identification of the chromatin regions coated by non-coding Xist RNA.
Cytogenetic and genome research 2009;125(1):19-25.
2009: Susumu Otsuka; Shinji Maegawa; Ayumi Takamura; Hideki Kamitani; Takashi Watanabe; Mitsuo Oshimura; Eiji Nanba
Aberrant promoter methylation and expression of the imprinted PEG3 gene in glioma.
Proceedings of the Japan Academy. Series B, Physical and biological sciences 2009;85(4):157-65.
2009: Norimasa Miura; Reina Sato; Tomoe Tsukamoto; Mika Shimizu; Hiroko Kabashima; Miho Takeda; Shunsaku Takahashi; Tomomi Harada; James E West; Harry A Drabkin; Jose E Mejia; Goshi Shiota; Yoshikazu Murawaki; Arvind Virmani; Adi F Gazdar; Mitsuo Oshimura; Junichi Hasegawa
A noncoding RNA gene on chromosome 10p15.3 may function upstream of hTERT.
BMC molecular biology 2009;10():5.
2008: Iveta Y Yotova; Irena M Vlatkovic; Florian M Pauler; Katarzyna E Warczok; Peter F Ambros; Mitsuo Oshimura; Hans-Christian Theussl; Manfred Gessler; Erwin F Wagner; Denise P Barlow
Identification of the human homolog of the imprinted mouse Air non-coding RNA.
Genomics 2008;92(6):464-73.
2008: Astrid C Haugen; Ajay Goel; Kanae Yamada; Giancarlo Marra; Thuy-Phuong Nguyen; Takeshi Nagasaka; Shinsaku Kanazawa; Junichi Koike; Yoshinori Kikuchi; Xiaoling Zhong; Michitsune Arita; Kazutoshi Shibuya; Mitsuo Oshimura; Hiromichi Hemmi; C Richard Boland; Minoru Koi
Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer.
Cancer research 2008;68(20):8465-72.
2008: Takeo Shibui; Yukari Higo; Takeo W Tsutsui; Minoru Uchida; Mitsuo Oshimura; J Carl Barrett; Takeki Tsutsui
Changes in expression of imprinted genes following treatment of human cancer cell lines with non-mutagenic or mutagenic carcinogens.
International journal of oncology 2008;33(2):351-60.
2008: Masaru Miyano; Shin-ichi Horike; Shutao Cai; Mitsuo Oshimura; Terumi Kohwi-Shigematsu
DLX5 expression is monoallelic and Dlx5 is up-regulated in the Mecp2-null frontal cortex.
Journal of cellular and molecular medicine 2008;12(4):1188-91.
2008: Phuongmai Nguyen; Hengmi Cui; Kheem S Bisht; Lunching Sun; Krish Patel; Richard S Lee; Hiroyuki Kugoh; Mitsuo Oshimura; Andrew P Feinberg; David Gius
CTCFL/BORIS is a methylation-independent DNA-binding protein that preferentially binds to the paternal H19 differentially methylated region.
Cancer research 2008;68(14):5546-51.
2008: Shingo Shitara; Minoru Kakeda; Keiko Nagata; Masaharu Hiratsuka; Akiko Sano; Kanako Osawa; Akiyo Okazaki; Motonobu Katoh; Yasuhiro Kazuki; Mitsuo Oshimura; Kazuma Tomizuka
Telomerase-mediated life-span extension of human primary fibroblasts by human artificial chromosome (HAC) vector.
Biochemical and biophysical research communications 2008;369(3):807-11.
2008: Yasuhiro Kazuki; Hidetoshi Hoshiya; Yoshiteru Kai; Satoshi Abe; M Takiguchi; M Osaki; S Kawazoe; Motonobu Katoh; Mito Kanatsu-Shinohara; K Inoue; N Kajitani; T Yoshino; Yasuaki Shirayoshi; Atsuo Ogura; Tokuyuki Shinohara; J Carl Barrett; Mitsuo Oshimura
Correction of a genetic defect in multipotent germline stem cells using a human artificial chromosome.
Gene therapy 2008;15(8):617-24.
2008: Hidetoshi Yamada; Yanze C Li; Mitsuo Nishikawa; Mitsuo Oshimura; Toshiaki Inoue
Introduction of a CD40L genomic fragment via a human artificial chromosome vector permits cell-type-specific gene expression and induces immunoglobulin secretion.
Journal of human genetics 2008;53(5):447-53.
2008: Mitsuo Oshimura; Motonobu Katoh
Transfer of human artificial chromosome vectors into stem cells.
Reproductive biomedicine online 2008;16(1):57-69.
2008: Yumi Nagahama; Mika Ishimaru; Mitsuhiko Osaki; Toshiaki Inoue; Akihiro Maeda; Chisato Nakada; Masatsugu Moriyama; Kenzo Sato; Mitsuo Oshimura; Hisao Ito
Apoptotic pathway induced by transduction of RUNX3 in the human gastric carcinoma cell line MKN-1.
Cancer science 2008;99(1):23-30.
2007: Masanori Takehashi; Mito Kanatsu-Shinohara; Hiromi Miki; Jiyoung Lee; Yasuhiro Kazuki; Kimiko Inoue; Narumi Ogonuki; Shinya Toyokuni; Mitsuo Oshimura; Atsuo Ogura; Takashi Shinohara
Production of knockout mice by gene targeting in multipotent germline stem cells.
Developmental biology 2007;312(1):344-52.
2007: Mitsuhiko Osaki; Toshiaki Inoue; Shigeyuki Yamaguchi; Aiko Inaba; Naruo Tokuyasu; Kuan-Teh Jeang; Mitsuo Oshimura; Hisao Ito
MAD1 (mitotic arrest deficiency 1) is a candidate for a tumor suppressor gene in human stomach.
Virchows Archiv : an international journal of pathology 2007;451(4):771-9.
2007: Ken-Ichi Nakamura; Kaiyo Takubo; Naotaka Izumiyama-Shimomura; Motoji Sawabe; Tomio Arai; Hiroshi Kishimoto; Mutsunori Fujiwara; Motonobu Kato; Mitsuo Oshimura; Akio Ishii; Naoshi Ishikawa
Telomeric DNA length in cerebral gray and white matter is associated with longevity in individuals aged 70 years or older.
Experimental gerontology 2007;42(10):944-50.
2007: Noriko Itaba-Matsumoto; Shinji Maegawa; Hidehisa Yamagata; Ikuko Kondo; Mitsuo Oshimura; Eiji Nanba
Imprinting status of paternally imprinted DLX5 gene in Japanese patients with Rett syndrome.
Brain & development 2007;29(8):491-5.
2007: Naoki Mukaida; Seiji Kodama; Keiji Suzuki; Mitsuo Oshimura; Masami Watanabe
Transmission of genomic instability from a single irradiated human chromosome to the progeny of unirradiated cells.
Radiation research 2007;167(6):675-81.
2007: Toshiaki Inoue; Masaharu Hiratsuka; Mitsuhiko Osaki; Mitsuo Oshimura
The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation.
Cell cycle (Georgetown, Tex.) 2007;6(9):1011-8.
2007: Nozomi Tomimatsu; Candice G T Tahimic; Akihiro Otsuki; Sandeep Burma; Akiko Fukuhara; Kenzo Sato; Goshi Shiota; Mitsuo Oshimura; David J Chen; Akihiro Kurimasa
Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks.
The Journal of biological chemistry 2007;282(14):10138-45.
2007: Toshiaki Inoue; Masaharu Hiratsuka; Mitsuhiko Osaki; H Yamada; I Kishimoto; S Yamaguchi; S Nakano; M Katoh; Hisao Ito; Mitsuo Oshimura
SIRT2, a tubulin deacetylase, acts to block the entry to chromosome condensation in response to mitotic stress.
Oncogene 2007;26(7):945-57.
2007: Hajime Kurosaki; Yasuhiro Kazuki; Masaharu Hiratsuka; Toshiaki Inoue; Yasuhisa Matsui; Chi Chiu Wang; Mito Kanatsu-Shinohara; Takashi Shinohara; Tosifusa Toda; Mitsuo Oshimura
A comparison study in the proteomic signatures of multipotent germline stem cells, embryonic stem cells, and germline stem cells.
Biochemical and biophysical research communications 2007;353(2):259-67.
2007: Masahiro Kawahara; Toshiaki Inoue; Xianying Ren; Takahiro Sogo; Hidetoshi Yamada; Motonobu Katoh; Hiroshi Ueda; Mitsuo Oshimura; Teruyuki Nagamune
Antigen-mediated growth control of hybridoma cells via a human artificial chromosome.
Biochimica et biophysica acta 2007;1770(2):206-12.
2007: Kazuhiro Murakami; Mitsuo Oshimura; Hiroyuki Kugoh
Suggestive evidence for chromosomal localization of non-coding RNA from imprinted LIT1.
Journal of human genetics 2007;52(11):926-33.
2006: Einosuke Mizuta; Hitomi Furuichi; Yasuhiro Kazuki; Junichiro Miake; Shuichi Yano; Udin Bahrudin; Yasutaka Yamamoto; Osamu Igawa; Chiaki Shigemasa; Kyoko Hidaka; Takayuki Morisaki; Yasutaka Kurata; Haruaki Ninomiya; Masafumi Kitakaze; Yasuaki Shirayoshi; Mitsuo Oshimura; Ichiro Hisatome
Delayed onset of beating and decreased expression of T-type Ca2+ channel in mouse ES cell-derived cardiocytes carrying human chromosome 21.
Biochemical and biophysical research communications 2006;351(1):126-32.
2006: Seiji Nakano; Kazuhiro Murakami; Makiko Meguro; Hidenobu Soejima; Ken Higashimoto; Takeshi Urano; Hiroyuki Kugoh; Tsunehiro Mukai; Masahide Ikeguchi; Mitsuo Oshimura
Expression profile of LIT1/KCNQ1OT1 and epigenetic status at the KvDMR1 in colorectal cancers.
Cancer science 2006;97(11):1147-54.
2006: Ko Ishihara; Mitsuo Oshimura; Mitsuyoshi Nakao
CTCF-dependent chromatin insulator is linked to epigenetic remodeling.
Molecular cell 2006;23(5):733-42.
2006: Akio Ishii; Ken-Ichi Nakamura; Hiroshi Kishimoto; Naoko Honma; Junko Aida; Motoji Sawabe; Tomio Arai; Mutsunori Fujiwara; Fujio Takeuchi; Motonobu Kato; Mitsuo Oshimura; Naotaka Izumiyama; Kaiyo Takubo
Telomere shortening with aging in the human pancreas.
Experimental gerontology 2006;41(9):882-6.
2006: Mito Kanatsu-Shinohara; Masahito Ikawa; Masanori Takehashi; Narumi Ogonuki; Hiromi Miki; Kimiko Inoue; Yasuhiro Kazuki; Jiyoung Lee; Shinya Toyokuni; Mitsuo Oshimura; Atsuo Ogura; Takashi Shinohara
Production of knockout mice by random or targeted mutagenesis in spermatogonial stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(21):8018-23.
2006: Yoshinori Ishikawa; Nobuyuki Tanaka; Kazuhiro Murakami; Toru Uchiyama; Satoru Kumaki; Shigeru Tsuchiya; Hiroyuki Kugoh; Mitsuo Oshimura; Michele P Calos; Kazuo Sugamura
Phage phiC31 integrase-mediated genomic integration of the common cytokine receptor gamma chain in human T-cell lines.
The journal of gene medicine 2006;8(5):646-53.
2006: Candice G T Tahimic; Nozomi Tomimatsu; Ryuichi Nishigaki; Akiko Fukuhara; Tosifusa Toda; Kozo Kaibuchi; Goshi Shiota; Mitsuo Oshimura; Akihiro Kurimasa
Evidence for a role of Collapsin response mediator protein-2 in signaling pathways that regulate the proliferation of non-neuronal cells.
Biochemical and biophysical research communications 2006;340(4):1244-50.
2006: Tetsuji Suda; Motonobu Katoh; Masaharu Hiratsuka; Masato Takiguchi; Yasuhiro Kazuki; Toshiaki Inoue; Mitsuo Oshimura
Heat-regulated production and secretion of insulin from a human artificial chromosome vector.
Biochemical and biophysical research communications 2006;340(4):1053-61.
2006: Shinya Matsuura; Yoshiyuki Matsumoto; Ken-ichi Morishima; Hideki Izumi; Hiroshi Matsumoto; Emi Ito; Keisuke Tsutsui; Junya Kobayashi; Hiroshi Tauchi; Yoshinori Kajiwara; Seiji Hama; Kaoru Kurisu; Hidetoshi Tahara; Mitsuo Oshimura; Kenshi Komatsu; Tatsuro Ikeuchi; Tadashi Kajii
Monoallelic BUB1B mutations and defective mitotic-spindle checkpoint in seven families with premature chromatid separation (PCS) syndrome.
American journal of medical genetics. Part A 2006;140(4):358-67.
2006: Xianying Ren; Candice G T Tahimic; Motonobu Katoh; Akihiro Kurimasa; Toshiaki Inoue; Mitsuo Oshimura
Human artificial chromosome vectors meet stem cells: new prospects for gene delivery.
Stem cell reviews 2006;2(1):43-50.
2006: Hidetoshi Yamada; Atsushi Kunisato; Masahiro Kawahara; Candice G T Tahimic; Xianying Ren; Hiroshi Ueda; Teruyuki Nagamune; Motonobu Katoh; Toshiaki Inoue; Mitsuo Nishikawa; Mitsuo Oshimura
Exogenous gene expression and growth regulation of hematopoietic cells via a novel human artificial chromosome.
Journal of human genetics 2006;51(2):147-50.
2005: Xianying Ren; Motonobu Katoh; Hidetoshi Hoshiya; Akihiro Kurimasa; Toshiaki Inoue; Fumiaki Ayabe; Kotaro Shibata; Junya Toguchida; Mitsuo Oshimura
A novel human artificial chromosome vector provides effective cell lineage-specific transgene expression in human mesenchymal stem cells.
Stem cells (Dayton, Ohio) 2005;23(10):1608-16.
2005: Ayano Yanagisawa; Chisato Endo; Katsuya Okawa; Shingo Shitara; Hiroyuki Kugoh; Makoto Kakitani; Mitsuo Oshimura; Kazuma Tomizuka
Generation of chromosome-specific monoclonal antibodies using in vitro-differentiated transchromosomic mouse embryonic stem cells.
Stem cells (Dayton, Ohio) 2005;23(10):1479-88.
2005: Mito Kanatsu-Shinohara; Narumi Ogonuki; Tomohiko Iwano; Jiyoung Lee; Yasuhiro Kazuki; Kimiko Inoue; Hiromi Miki; Masanori Takehashi; Shinya Toyokuni; Yoichi Shinkai; Mitsuo Oshimura; Fumitoshi Ishino; Atsuo Ogura; Takashi Shinohara
Genetic and epigenetic properties of mouse male germline stem cells during long-term culture.
Development (Cambridge, England) 2005;132(18):4155-63.
2005: Ryuichi Nishigaki; Mitsuhiko Osaki; Masaharu Hiratsuka; Tosifusa Toda; Kaori Murakami; Kuan-Teh Jeang; Hisao Ito; Toshiaki Inoue; Mitsuo Oshimura
Proteomic identification of differentially-expressed genes in human gastric carcinomas.
Proteomics 2005;5(12):3205-13.
2005: Hiromi Tanaka; Izumi Horikawa; J Carl Barrett; Mitsuo Oshimura
Evidence for inactivation of distinct telomerase repressor genes in different types of human cancers.
International journal of cancer. Journal international du cancer 2005;115(4):653-7.
2005: Minoru Kakeda; M Hiratsuka; K Nagata; Yoshimi Kuroiwa; Makoto Kakitani; M Katoh; Mitsuo Oshimura; Kazuma Tomizuka
Human artificial chromosome (HAC) vector provides long-term therapeutic transgene expression in normal human primary fibroblasts.
Gene therapy 2005;12(10):852-6.
2005: Akihiro Otsuki; Candice G T Tahimic; Nozomi Tomimatsu; Motonobu Katoh; David J Chen; Akihiro Kurimasa; Mitsuo Oshimura
Construction of a novel expression system on a human artificial chromosome.
Biochemical and biophysical research communications 2005;329(3):1018-25.
2005: Wataru Yasui; Mitsuo Oshimura; Kazuhiko Igarashi; Hisao Ito; Eiichi Tahara
Cancer and epigenetics--basic research and clinical implications: Joint Meeting of the Fourteenth International Symposium of the Hiroshima Cancer Seminar and the Eighth Meeting of the Tottori Bioscience Promotion Foundation, October 2004.
Cancer science 2005;96(4):245-8.
2005: Lichun Yang; Alfred Chi Chung Leung; Josephine Mun Yee Ko; Paulisally H Y Lo; Johnny Cheuk On Tang; Gopesh Srivastava; Mitsuo Oshimura; Eric J Stanbridge; Yataro Daigo; Yusuke Nakamura; Cecilia Man Ching Tang; Kwok-Wai Lau; Simon Law; Maria Li Lung
Tumor suppressive role of a 2.4 Mb 9q33-q34 critical region and DEC1 in esophageal squamous cell carcinoma.
Oncogene 2005;24(4):697-705.
2005: Fumiaki Ayabe; Motonobu Katoh; Toshiaki Inoue; Natalay Kouprina; Vladimir Larionov; Mitsuo Oshimura
A novel expression system for genomic DNA loci using a human artificial chromosome vector with transformation-associated recombination cloning.
Journal of human genetics 2005;50(11):592-9.
2005: Jennifer M Spence; R E Keith Fournier; Mitsuo Oshimura; Vinciane Regnier; Christine J Farr
Topoisomerase II cleavage activity within the human D11Z1 and DXZ1 alpha-satellite arrays.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2005;13(6):637-48.
2005: Takahiro Arima; Tetsuya Kamikihara; Toshirou Hayashida; Kiyoko Kato; Toshiaki Inoue; Yasuaki Shirayoshi; Mitsuo Oshimura; Hidenobu Soejima; Tunehiro Mukai; Norio Wake
ZAC, LIT1 (KCNQ1OT1) and p57KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith-Wiedemann syndrome.
Nucleic acids research 2005;33(8):2650-60.
2005: Masayuki Haruta; Makiko Meguro; Yu-ki Sakamoto; Hidetoshi Hoshiya; Akiko Kashiwagi; Yasuhiko Kaneko; Kohzoh Mitsuya; Mitsuo Oshimura
Narrowed abrogation of the Angelman syndrome critical interval on human chromosome 15 does not interfere with epigenotype maintenance in somatic cells.
Journal of human genetics 2005;50(3):124-32.
2005: Daisuke Kobayashi; Ichiro Ieiri; Takeshi Hirota; Hiroshi Takane; Shinji Maegawa; Junzo Kigawa; Hiroshi Suzuki; Eiji Nanba; Mitsuo Oshimura; Naoki Terakawa; Kenji Otsubo; Kazunori Mine; Yuichi Sugiyama
Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(1):94-101.
2004: Mito Kanatsu-Shinohara; Kimiko Inoue; Jiyoung Lee; Momoko Yoshimoto; Narumi Ogonuki; Hiromi Miki; Shiro Baba; Takeo Kato; Yasuhiro Kazuki; Shinya Toyokuni; Megumi Toyoshima; Ohtsura Niwa; Mitsuo Oshimura; Toshio Heike; Tatsutoshi Nakahata; Fumitoshi Ishino; Atsuo Ogura; Takashi Shinohara
Generation of pluripotent stem cells from neonatal mouse testis.
Cell 2004;119(7):1001-12.
2004: Hirofumi Nakanishi; Tetsuji Suda; Motonobu Katoh; Akiko Watanabe; Tadashi Igishi; Masahiro Kodani; Shingo Matsumoto; Masaki Nakamoto; Yasushi Shigeoka; Tetsuro Okabe; Mitsuo Oshimura; Eiji Shimizu
Loss of imprinting of PEG1/MEST in lung cancer cell lines.
Oncology reports 2004;12(6):1273-8.
2004: Takeshi Hirota; Ichiro Ieiri; Hiroshi Takane; Shinji Maegawa; Masakiyo Hosokawa; Kaoru Kobayashi; Kan Chiba; Eiji Nanba; Mitsuo Oshimura; Tetsuo Sato; Shun Higuchi; Kenji Otsubo
Allelic expression imbalance of the human CYP3A4 gene and individual phenotypic status.
Human molecular genetics 2004;13(23):2959-69.
2004: Hiroyuki Torisu; Toshiyuki Yamamoto; Takehisa Fujiwaki; Mitsutaka Kadota; Mitsuo Oshimura; Kenji Kurosawa; Shinjiro Akaboshi; Akira Oka
Girl with monosomy 1p36 and Angelman syndrome due to unbalanced der(1) transmission of a maternal translocation t(1;15)(p36.3;q13.1).
American journal of medical genetics. Part A 2004;131(1):94-8.
2004: Emily L Niemitz; Michael R DeBaun; Jonathan Fallon; Kazuhiro Murakami; Hiroyuki Kugoh; Mitsuo Oshimura; Andrew P Feinberg
Microdeletion of LIT1 in familial Beckwith-Wiedemann syndrome.
American journal of human genetics 2004;75(5):844-9.
2004: Katsuyoshi Horibata; Yuka Iwamoto; Isao Kuraoka; Nicolaas G J Jaspers; Akihiro Kurimasa; Mitsuo Oshimura; Masamitsu Ichihashi; Kiyoji Tanaka
Complete absence of Cockayne syndrome group B gene product gives rise to UV-sensitive syndrome but not Cockayne syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(43):15410-5.
2004: Kaori Murakami; Ryuichi Nishigaki; Yasuhiro Kazuki; Mitsutaka Kadota; Mitsuo Oshimura
[Proteomics and epigenetics learned from Down syndrome model mouse].
Seikagaku. The Journal of Japanese Biochemical Society 2004;76(10):1296-304.
2004: Wenqiang Yu; Vasudeva Ginjala; Vinod Pant; Igor Chernukhin; Joanne Whitehead; France Docquier; Dawn Farrar; Gholamreza Tavoosidana; Rituparna Mukhopadhyay; Chandrasekhar Kanduri; Mitsuo Oshimura; Andrew P Feinberg; Victor Lobanenkov; Elena Klenova; Rolf Ohlsson
Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation.
Nature genetics 2004;36(10):1105-10.
2004: Sumitaka Yamanaka; Makoto Sunamura; Toru Furukawa; Libo Sun; Liviu P Lefter; Tadayoshi Abe; Toshimasa Yatsuoka; Hiroko Fujimura; Emiko Shibuya; Noriko Kotobuki; Mitsuo Oshimura; Akira Sakurada; Masami Sato; Takashi Kondo; Seiki Matsuno; Akira Horii
Chromosome 12, frequently deleted in human pancreatic cancer, may encode a tumor-suppressor gene that suppresses angiogenesis.
Laboratory investigation; a journal of technical methods and pathology 2004;84(10):1339-51.
2004: Liviu P Lefter; Viorel Scripcaru; Makoto Sunamura; Toru Furukawa; Seiki Matsuno; Mitsuo Oshimura; Vasile Drug; Cristian Dragomir; Akira Horii
Screening for functional tumor suppressor activity in pancreatic cancer.
Romanian journal of gastroenterology 2004;13(3):195-201.
2004: Mitsuhiko Osaki; Masatsugu Moriyama; K Adachi; Chisato Nakada; A Takeda; Y Inoue; H Adachi; Kenzo Sato; Mitsuo Oshimura; Hisao Ito
Expression of RUNX3 protein in human gastric mucosa, intestinal metaplasia and carcinoma.
European journal of clinical investigation 2004;34(9):605-12.
2004: Motonobu Katoh; Fumiaki Ayabe; Satoko Norikane; Teruaki Okada; Hiroshi Masumoto; Shin-ichi Horike; Yasuaki Shirayoshi; Mitsuo Oshimura
Construction of a novel human artificial chromosome vector for gene delivery.
Biochemical and biophysical research communications 2004;321(2):280-90.
2004: Kazuhiko Nakabayashi; S Makino; S Minagawa; A C Smith; J S Bamforth; Philip Stanier; Michael Preece; L Parker-Katiraee; T Paton; Mitsuo Oshimura; Pleasantine Mill; Y Yoshikawa; C C Hui; David Monk; Gudrun E Moore; Stephen W Scherer
Genomic imprinting of PPP1R9A encoding neurabin I in skeletal muscle and extra-embryonic tissues.
Journal of medical genetics 2004;41(8):601-8.
2004: Tatsuo Fukagawa; Masahiro Nogami; Mitsuko Yoshikawa; Masashi Ikeno; Tuneko Okazaki; Yasunari Takami; Tatsuo Nakayama; Mitsuo Oshimura
Dicer is essential for formation of the heterochromatin structure in vertebrate cells.
Nature cell biology 2004;6(8):784-91.
2004: Hidenobu Soejima; Tetsuji Nakagawachi; Wei Zhao; Ken Higashimoto; Takeshi Urano; Shiroh Matsukura; Yoshihiko Kitajima; Makoto Takeuchi; Masahiro Nakayama; Mitsuo Oshimura; Kohji Miyazaki; Keiichiro Joh; Tsunehiro Mukai
Silencing of imprinted CDKN1C gene expression is associated with loss of CpG and histone H3 lysine 9 methylation at DMR-LIT1 in esophageal cancer.
Oncogene 2004;23(25):4380-8.
2004: Yasuhiro Kazuki; Motoshi Kimura; Ryuichi Nishigaki; Yoshiteru Kai; Satoshi Abe; Chiga Okita; Yasuaki Shirayoshi; Thomas C Schulz; Kazuma Tomizuka; Kazunori Hanaoka; Toshiaki Inoue; Mitsuo Oshimura
Human chromosome 21q22.2-qter carries a gene(s) responsible for downregulation of mlc2a and PEBP in Down syndrome model mice.
Biochemical and biophysical research communications 2004;317(2):491-9.
2004: Makoto Sunamura; Liviu P Lefter; Dan G Duda; Rina Morita; Hiroko Inoue; Tadaaki Yokoyama; Toshimasa Yatsuoka; Tadayoshi Abe; Shinichi Egawa; Toru Furukawa; Shinichi Fukushige; Mitsuo Oshimura; Akira Horii; Seiki Matsuno
The role of chromosome 18 abnormalities in the progression of pancreatic adenocarcinoma.
Pancreas 2004;28(3):311-6.
2004: Yuki Nakamura; Fumihito Tajima; Kiyomi Ishiga; Hidetoshi Yamazaki; Mitsuo Oshimura; Goshi Shiota; Yoshikazu Murawaki
Soluble c-kit receptor mobilizes hematopoietic stem cells to peripheral blood in mice.
Experimental hematology 2004;32(4):390-6.
2004: Takahiro Yamada; Kohzoh Mitsuya; Tomohiko Kayashima; Kentaro Yamasaki; Tohru Ohta; Koh-ichiro Yoshiura; Naomichi Matsumoto; Hideto Yamada; Hisanori Minakami; Mitsuo Oshimura; Norio Niikawa; Tatsuya Kishino
Imprinting analysis of 10 genes and/or transcripts in a 1.5-Mb MEST-flanking region at human chromosome 7q32.
Genomics 2004;83(3):402-12.
2004: Shinji Maegawa; Noriko Itaba; Susumu Otsuka; Hideki Kamitani; Takashi Watanabe; Candice G T Tahimic; Eiji Nanba; Mitsuo Oshimura
Coordinate downregulation of a novel imprinted transcript ITUP1 with PEG3 in glioma cell lines.
DNA research : an international journal for rapid publication of reports on genes and genomes 2004;11(1):37-49.
2004: Chi Chiu Wang; Mitsutaka Kadota; Ryuichi Nishigaki; Yasuhiro Kazuki; Yasuaki Shirayoshi; Michael Scott Rogers; Takashi Gojobori; Kazuho Ikeo; Mitsuo Oshimura
Molecular hierarchy in neurons differentiated from mouse ES cells containing a single human chromosome 21.
Biochemical and biophysical research communications 2004;314(2):335-50.
2004: Mitsutaka Kadota; Ryuichi Nishigaki; Chi Chiu Wang; Tosifusa Toda; Yasuaki Shirayoshi; Toshiaki Inoue; Takashi Gojobori; Kazuho Ikeo; Michael Scott Rogers; Mitsuo Oshimura
Proteomic signatures and aberrations of mouse embryonic stem cells containing a single human chromosome 21 in neuronal differentiation: an in vitro model of Down syndrome.
Neuroscience 2004;129(2):325-35.
2004: Motoshi I Kimura; Yasuhiro Kazuki; Akiko Kashiwagi; Yoshiteru Kai; Satoshi Abe; Ottavia Barbieri; Giovanni Levi; Mitsuo Oshimura
Dlx5, the mouse homologue of the human-imprinted DLX5 gene, is biallelically expressed in the mouse brain.
Journal of human genetics 2004;49(5):273-7.
2003: Hiroki Kamino; Masaharu Hiratsuka; Tosifusa Toda; Ryuichi Nishigaki; Mitsuhiko Osaki; Hisao Ito; Toshiaki Inoue; Mitsuo Oshimura
Searching for genes involved in arteriosclerosis: proteomic analysis of cultured human umbilical vein endothelial cells undergoing replicative senescence.
Cell structure and function 2003;28(6):495-503.
2003: Liviu P Lefter; Makoto Sunamura; Toru Furukawa; Kazunori Takeda; Noriko Kotobuki; Mitsuo Oshimura; Seiki Matsuno; Akira Horii
Inserting chromosome 18 into pancreatic cancer cells switches them to a dormant metastatic phenotype.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(13):5044-52.
2003: Ken Higashimoto; Takeshi Urano; Kazumitsu Sugiura; Hitomi Yatsuki; Keiichiro Joh; Wei Zhao; Mayumi Iwakawa; Hirofumi Ohashi; Mitsuo Oshimura; Norio Niikawa; Tsunehiro Mukai; Hidenobu Soejima
Loss of CpG methylation is strongly correlated with loss of histone H3 lysine 9 methylation at DMR-LIT1 in patients with Beckwith-Wiedemann syndrome.
American journal of human genetics 2003;73(4):948-56.
2003: Masaharu Hiratsuka; Toshiaki Inoue; Tosifusa Toda; Narimichi Kimura; Yasuaki Shirayoshi; Hideki Kamitani; Takashi Watanabe; Eisaku Ohama; Candice G T Tahimic; Akihiro Kurimasa; Mitsuo Oshimura
Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene.
Biochemical and biophysical research communications 2003;309(3):558-66.
2003: Satoshi Fujii; Robert Z Luo; Jiuhong Yuan; Mitsutaka Kadota; Mitsuo Oshimura; Sharon R Dent; Yutaka Kondo; Jean-Pierre J Issa; Robert C Bast; Yinhua Yu
Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation.
Human molecular genetics 2003;12(15):1791-800.
2003: Tetsuji Suda; Motonobu Katoh; Masaharu Hiratsuka; Mutsunori Fujiwara; Yoshito Irizawa; Mitsuo Oshimura
Use of real-time RT-PCR for the detection of allelic expression of an imprinted gene.
International journal of molecular medicine 2003;12(2):243-6.
2003: Jiuhong Yuan; Robert Z Luo; Satoshi Fujii; Lin Wang; Wei Hu; Michael Andreeff; Yong Pan; Mitsutaka Kadota; Mitsuo Oshimura; Aysegul A Sahin; Jean-Pierre J Issa; Robert C Bast; Yinhua Yu
Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.
Cancer research 2003;63(14):4174-80.
2003: Itoshi Nikaido; Chika Saito; Yosuke Mizuno; Makiko Meguro; Hidemasa Bono; Moritoshi Kadomura; Tomohiro Kono; Gerard A J Morris; Paul A Lyons; Mitsuo Oshimura; Yoshihide Hayashizaki; Yasushi Okazaki
Discovery of imprinted transcripts in the mouse transcriptome using large-scale expression profiling.
Genome research 2003;13(6B):1402-9.
2003: Chiga Okita; Makiko Meguro; Hidetoshi Hoshiya; Masayuki Haruta; Yu-ki Sakamoto; Mitsuo Oshimura
A new imprinted cluster on the human chromosome 7q21-q31, identified by human-mouse monochromosomal hybrids.
Genomics 2003;81(6):556-9.
2003: Yinhua Yu; Satoshi Fujii; Jiuhong Yuan; Robert Z Luo; Lin Wang; Jiaju Bao; Mitsutaka Kadota; Mitsuo Oshimura; Sharon R Dent; Jean-Pierre J Issa; Robert C Bast
Epigenetic regulation of ARHI in breast and ovarian cancer cells.
Annals of the New York Academy of Sciences 2003;983():268-77.
2003: Yann Jouvenot; Vasudeva Ginjala; Lei Zhang; Pei-Qi Liu; Mitsuo Oshimura; Andrew P Feinberg; A P Wolffe; Rolf Ohlsson; Philip D Gregory
Targeted regulation of imprinted genes by synthetic zinc-finger transcription factors.
Gene therapy 2003;10(6):513-22.
2003: Toshio Yawata; Hiroki Kamino; Hiroyuki Kugoh; Motonobu Katoh; Nobuo Nomura; Michio Oishi; Izumi Horikawa; J Carl Barrett; Mitsuo Oshimura
Identification of a
Oncogene 2003;22(2):281-90.

2003: Yasuhiro Kazuki; Thomas C Schulz; Tokuyuki Shinohara; Mitsutaka Kadota; Ryuichi Nishigaki; Toshiaki Inoue; M Kimura; Yoshiteru Kai; Satoshi Abe; Yasuaki Shirayoshi; Mitsuo Oshimura
A new mouse model for Down syndrome.
Journal of neural transmission. Supplementum 2003;(67):1-20.
2003: Hidetoshi Hoshiya; Makiko Meguro; Akiko Kashiwagi; Chiga Okita; Mitsuo Oshimura
Calcr, a brain-specific imprinted mouse calcitonin receptor gene in the imprinted cluster of the proximal region of chromosome 6.
Journal of human genetics 2003;48(4):208-11.
2003: Akiko Kashiwagi; Makiko Meguro; Hidetoshi Hoshiya; Masayuki Haruta; Fumitoshi Ishino; Toshiyuki Shibahara; Mitsuo Oshimura
Predominant maternal expression of the mouse Atp10c in hippocampus and olfactory bulb.
Journal of human genetics 2003;48(4):194-8.
2003: Hiroyuki Kugoh; Katsuyo Shigenami; Kenji Funaki; J Carl Barrett; Mitsuo Oshimura
Human chromosome 5 carries a putative telomerase repressor gene.
Genes, chromosomes & cancer 2003;36(1):37-47.
2002: Mitsutaka Kadota; Yasuaki Shirayoshi; Mitsuo Oshimura
Elevated apoptosis in pre-mature neurons differentiated from mouse ES cells containing a single human chromosome 21.
Biochemical and biophysical research communications 2002;299(4):599-605.
2002: Andrew P Feinberg; Mitsuo Oshimura; J Carl Barrett
Epigenetic mechanisms in human disease.
Cancer research 2002;62(22):6784-7.
2002: Ken-Ichi Nakamura; Naotaka Izumiyama-Shimomura; Motoji Sawabe; Tomio Arai; Yukitoshi Aoyagi; Mutsunori Fujiwara; Eiju Tsuchiya; Yasuhito Kobayashi; Motonobu Kato; Mitsuo Oshimura; Koji Sasajima; Kei Nakachi; Kaiyo Takubo
Comparative analysis of telomere lengths and erosion with age in human epidermis and lingual epithelium.
The Journal of investigative dermatology 2002;119(5):1014-9.
2002: Hiroyuki Kugoh; Hiroko Nakamoto; Jun Inoue; Kenji Funaki; J Carl Barrett; Mitsuo Oshimura
Multiple human chromosomes carrying tumor-suppressor functions for the mouse melanoma cell line B16-F10, identified by microcell-mediated chromosome transfer.
Molecular carcinogenesis 2002;35(3):148-56.
2002: Naohiro Hori; Hiroshi Nakano; Toshiyuki Takeuchi; Hiroyuki Kato; Sayuri Hamaguchi; Mitsuo Oshimura; Kenzo Sato
A dyad oct-binding sequence functions as a maintenance sequence for the unmethylated state within the H19/Igf2-imprinted control region.
The Journal of biological chemistry 2002;277(31):27960-7.
2002: Kazuhiko Nakabayashi; Louise Bentley; Megan P Hitchins; Kohzoh Mitsuya; Makiko Meguro; Sachi Minagawa; John S Bamforth; Philip Stanier; Michael Preece; Rosanna Weksberg; Mitsuo Oshimura; Gudrun E Moore; Stephen W Scherer
Identification and characterization of an imprinted antisense RNA (MESTIT1) in the human MEST locus on chromosome 7q32.
Human molecular genetics 2002;11(15):1743-56.
2002: Ryuichi Nishigaki; Tokuyuki Shinohara; Tosifusa Toda; Akira Omori; Sachiyo Ichinose; Masayuki Itoh; Yasuaki Shirayoshi; Akihiro Kurimasa; Mitsuo Oshimura
An extra human chromosome 21 reduces mlc-2a expression in chimeric mice and Down syndrome.
Biochemical and biophysical research communications 2002;295(1):112-8.
2002: Shigeru Hosoki; Sho Ota; Yayoi Ichikawa; Hiroyoshi Suzuki; Takeshi Ueda; Yukio Naya; Koichiro Akakura; Tatsuo Igarashi; Mitsuo Oshimura; Naoki Nihei; J Carl Barrett; Tomohiko Ichikawa; Haruo Ito
Suppression of metastasis of rat prostate cancer by introduction of human chromosome 13.
Asian journal of andrology 2002;4(2):131-6.
2002: Takashi Sekiya; Tsutomu Nakamura; Yasuhiro Kazuki; Mitsuo Oshimura; Kazuyoshi Kohu; Ken-Ichi Tago; Susumu Ohwada; Tetsu Akiyama
Overexpression of Icat induces G(2) arrest and cell death in tumor cell mutants for adenomatous polyposis coli, beta-catenin, or Axin.
Cancer research 2002;62(11):3322-6.
2002: Yoshimi Kuroiwa; Hitoshi Yoshida; T Ohshima; Tokuyuki Shinohara; Atsuko Ohguma; Yasuhiro Kazuki; Mitsuo Oshimura; Isao Ishida; Kazuma Tomizuka
The use of chromosome-based vectors for animal transgenesis.
Gene therapy 2002;9(11):708-12.
2002: Liviu P Lefter; Toru Furukawa; Makoto Sunamura; Dan G Duda; Kazunori Takeda; Noriko Kotobuki; Mitsuo Oshimura; Seiki Matsuno; Akira Horii
Suppression of the tumorigenic phenotype by chromosome 18 transfer into pancreatic cancer cell lines.
Genes, chromosomes & cancer 2002;34(2):234-42.
2002: Kaiyo Takubo; Naotaka Izumiyama-Shimomura; Naoko Honma; Motoji Sawabe; Tomio Arai; Motonobu Kato; Mitsuo Oshimura; Ken-Ichi Nakamura
Telomere lengths are characteristic in each human individual.
Experimental gerontology 2002;37(4):523-31.
2002: Yosuke Mizuno; Yusuke Sotomaru; Yukiko Katsuzawa; Tomohiro Kono; Makiko Meguro; Mitsuo Oshimura; Jun Kawai; Yasuhiro Tomaru; Hidenori Kiyosawa; Itoshi Nikaido; Hiroshi Amanuma; Yoshihide Hayashizaki; Yasushi Okazaki
Asb4, Ata3, and Dcn are novel imprinted genes identified by high-throughput screening using RIKEN cDNA microarray.
Biochemical and biophysical research communications 2002;290(5):1499-505.
2002: Kazuhiko Nakabayashi; Bridget A Fernandez; Ikuko Teshima; Cheryl Shuman; Virginia K Proud; Cynthia J Curry; David Chitayat; Theresa Grebe; Jeffrey Ming; Mitsuo Oshimura; Makiko Meguro; Kohzoh Mitsuya; Paromita Deb-Rinker; Jo-Anne Herbrick; Rosanna Weksberg; Stephen W Scherer
Molecular genetic studies of human chromosome 7 in Russell-Silver syndrome.
Genomics 2002;79(2):186-96.
2001: M Kohda; Hidetoshi Hoshiya; Motonobu Katoh; I Tanaka; R Masuda; T Takemura; M Fujiwara; Mitsuo Oshimura
Frequent loss of imprinting of IGF2 and MEST in lung adenocarcinoma.
Molecular carcinogenesis 2001;31(4):184-91.
2001: Takahiro Arima; Robert A Drewell; Katharine L Arney; J Inoue; Y Makita; A Hata; Mitsuo Oshimura; N Wake; M Azim Surani
A conserved imprinting control region at the HYMAI/ZAC domain is implicated in transient neonatal diabetes mellitus.
Human molecular genetics 2001;10(14):1475-83.
2001: Takashi Sakatani; M Wei; Motonobu Katoh; Chiga Okita; D Wada; Kohzoh Mitsuya; Makiko Meguro; Masahide Ikeguchi; Hisao Ito; B Tycko; Mitsuo Oshimura
Epigenetic heterogeneity at imprinted loci in normal populations.
Biochemical and biophysical research communications 2001;283(5):1124-30.
2001: Tokuyuki Shinohara; Kazuma Tomizuka; S Miyabara; S Takehara; Yasuhiro Kazuki; J Inoue; Motonobu Katoh; H Nakane; Akihiro Iino; Atsuko Ohguma; S Ikegami; K Inokuchi; Isao Ishida; Roger H Reeves; Mitsuo Oshimura
Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Down's syndrome.
Human molecular genetics 2001;10(11):1163-75.
2001: Shinji Maegawa; H Yoshioka; N Itaba; N Kubota; S Nishihara; Y Shirayoshi; Eiji Nanba; Mitsuo Oshimura
Epigenetic silencing of PEG3 gene expression in human glioma cell lines.
Molecular carcinogenesis 2001;31(1):1-9.
2001: Makiko Meguro; Akiko Kashiwagi; Kohzoh Mitsuya; M Nakao; I Kondo; S Saitoh; Mitsuo Oshimura
A novel maternally expressed gene, ATP10C, encodes a putative aminophospholipid translocase associated with Angelman syndrome.
Nature genetics 2001;28(1):19-20.
2001: A Nishimoto; N Miura; Izumi Horikawa; Hiroyuki Kugoh; Y Murakami; S Hirohashi; H Kawasaki; A F Gazdar; J W Shay; J Carl Barrett; Mitsuo Oshimura
Functional evidence for a telomerase repressor gene on human chromosome 10p15.1.
Oncogene 2001;20(7):828-35.
2001: Makiko Meguro; Kohzoh Mitsuya; N Nomura; M Kohda; Akiko Kashiwagi; Ryuichi Nishigaki; H Yoshioka; M Nakao; M Oishi; Mitsuo Oshimura
Large-scale evaluation of imprinting status in the Prader-Willi syndrome region: an imprinted direct repeat cluster resembling small nucleolar RNA genes.
Human molecular genetics 2001;10(4):383-94.
2001: H Yoshioka; Yasuaki Shirayoshi; Mitsuo Oshimura
A novel in vitro system for analyzing parental allele-specific histone acetylation in genomic imprinting.
Journal of human genetics 2001;46(11):626-32.
2001: Yasuhiro Kazuki; Tokuyuki Shinohara; Kazuma Tomizuka; Motonobu Katoh; Atsuko Ohguma; Isao Ishida; Mitsuo Oshimura
Germline transmission of a transferred human chromosome 21 fragment in transchromosomal mice.
Journal of human genetics 2001;46(10):600-3.
2001: K Tanaka; Goshi Shiota; Makiko Meguro; Kohzoh Mitsuya; Mitsuo Oshimura; Hironaka Kawasaki
Loss of imprinting of long QT intronic transcript 1 in colorectal cancer.
Oncology 2001;60(3):268-73.
2001: J Inoue; Kohzoh Mitsuya; Shinji Maegawa; Hiroyuki Kugoh; Mitsutaka Kadota; D Okamura; Tokuyuki Shinohara; S Nishihara; S Takehara; K Yamauchi; Thomas C Schulz; Mitsuo Oshimura
Construction of 700 human/mouse A9 monochromosomal hybrids and analysis of imprinted genes on human chromosome 6.
Journal of human genetics 2001;46(3):137-45.
2000: Kaiyo Takubo; Ken-Ichi Nakamura; Naotaka Izumiyama; E Furugori; Motoji Sawabe; Tomio Arai; Yukiyoshi Esaki; Ken-ichi Mafune; Makoto Kammori; Mutsunori Fujiwara; Motonobu Kato; Mitsuo Oshimura; Koji Sasajima
Telomere shortening with aging in human liver.
The journals of gerontology. Series A, Biological sciences and medical sciences 2000;55(11):B533-6.
2000: Masataka Taga; Kazunori Shiraishi; Tsutomu Shimura; Norio Uematsu; Mitsuo Oshimura; Ohtsura Niwa
Increased frequencies of gene and chromosome mutations after X-irradiation in mouse embryonal carcinoma cells transfected with the bcl-2 gene.
Japanese journal of cancer research : Gann 2000;91(10):994-1000.
2000: Yoshimi Kuroiwa; Kazuma Tomizuka; Tokuyuki Shinohara; Yasuhiro Kazuki; Hitoshi Yoshida; Atsuko Ohguma; T Yamamoto; S Tanaka; Mitsuo Oshimura; Isao Ishida
Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts.
Nature biotechnology 2000;18(10):1086-90.
2000: Ken-Ichi Nakamura; E Furugori; Yukiyoshi Esaki; Tomio Arai; Motoji Sawabe; I Okayasu; Mutsunori Fujiwara; Makoto Kammori; Ken-ichi Mafune; Motonobu Kato; Mitsuo Oshimura; Koji Sasajima; Kaiyo Takubo
Correlation of telomere lengths in normal and cancers tissue in the large bowel.
Cancer letters 2000;158(2):179-84.
2000: Tomohiko Ichikawa; S Hosoki; Hiroshi Suzuki; Koichiro Akakura; Tatsuo Igarashi; Y Furuya; Mitsuo Oshimura; C W Rinker-Schaeffer; Naoki Nihei; J Carl Barrett; John T Isaacs; Haruo Ito
Mapping of metastasis suppressor genes for prostate cancer by microcell-mediated chromosome transfer.
Asian journal of andrology 2000;2(3):167-71.
2000: Masataka Taga; Kazunori Shiraishi; Tsutomu Shimura; Norio Uematsu; Tatsuhisa Kato; Y Nishimune; S Aizawa; Mitsuo Oshimura; Ohtsura Niwa
The effect of caffeine on p53-dependent radioresponses in undifferentiated mouse embryonal carcinoma cells after X-ray and UV-irradiations.
Journal of radiation research 2000;41(3):227-41.
2000: Shin-ichi Horike; Kohzoh Mitsuya; Makiko Meguro; N Kotobuki; Akiko Kashiwagi; T Notsu; Thomas C Schulz; Yasuaki Shirayoshi; Mitsuo Oshimura
Targeted disruption of the human LIT1 locus defines a putative imprinting control element playing an essential role in Beckwith-Wiedemann syndrome.
Human molecular genetics 2000;9(14):2075-83.
2000: Takahiro Arima; Robert A Drewell; Mitsuo Oshimura; N Wake; M Azim Surani
A novel imprinted gene, HYMAI, is located within an imprinted domain on human chromosome 6 containing ZAC.
Genomics 2000;67(3):248-55.
2000: S Nishihara; T Hayashida; Kohzoh Mitsuya; Thomas C Schulz; Masahide Ikeguchi; N Kaibara; Mitsuo Oshimura
Multipoint imprinting analysis in sporadic colorectal cancers with and without microsatellite instability.
International journal of oncology 2000;17(2):317-22.
2000: Toshiaki Inoue; Tokuyuki Shinohara; S Takehara; J Inoue; H Kamino; Hiroyuki Kugoh; Mitsuo Oshimura
Specific impairment of cardiogenesis in mouse ES cells containing a human chromosome 21.
Biochemical and biophysical research communications 2000;273(1):219-24.
2000: Kazuma Tomizuka; Tokuyuki Shinohara; Hitoshi Yoshida; H Uejima; Atsuko Ohguma; S Tanaka; K Sato; Mitsuo Oshimura; Isao Ishida
Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(2):722-7.
2000: Hiroyuki Kugoh; M Fujiwara; K Kihara; I Fukui; Izumi Horikawa; Thomas C Schulz; Mitsuo Oshimura
Cellular senescence of a human bladder carcinoma cell line (JTC-32) induced by a normal chromosome 11.
Cancer genetics and cytogenetics 2000;116(2):158-63.
2000: Tokuyuki Shinohara; Kazuma Tomizuka; S Takehara; K Yamauchi; Motonobu Katoh; Atsuko Ohguma; Isao Ishida; Mitsuo Oshimura
Stability of transferred human chromosome fragments in cultured cells and in mice.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2000;8(8):713-25.
1999: Hiromi Tanaka; Izumi Horikawa; Hiroyuki Kugoh; M Shimizu; J Carl Barrett; Mitsuo Oshimura
Telomerase-independent senescence of human immortal cells induced by microcell-mediated chromosome transfer.
Molecular carcinogenesis 1999;25(4):249-55.
1999: Kohzoh Mitsuya; Makiko Meguro; Maxwell P Lee; Motonobu Katoh; Thomas C Schulz; Hiroyuki Kugoh; M A Yoshida; N Niikawa; Andrew P Feinberg; Mitsuo Oshimura
LIT1, an imprinted antisense RNA in the human KvLQT1 locus identified by screening for differentially expressed transcripts using monochromosomal hybrids.
Human molecular genetics 1999;8(7):1209-17.
1999: Hiroyuki Kugoh; Kohzoh Mitsuya; Makiko Meguro; Katsuyo Shigenami; Thomas C Schulz; Mitsuo Oshimura
Mouse A9 cells containing single human chromosomes for analysis of genomic imprinting.
DNA research : an international journal for rapid publication of reports on genes and genomes 1999;6(3):165-72.
1999: Maxwell P Lee; Michael R DeBaun; Kohzoh Mitsuya; Heidi L Galonek; Sheri A Brandenburg; Mitsuo Oshimura; Andrew P Feinberg
Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5203-8.
1999: Naoki Nihei; S Ohta; Hiroaki Kuramochi; H Kugoh; Mitsuo Oshimura; J Carl Barrett; John T Isaacs; Tatsuo Igarashi; Haruo Ito; M Masai; Yayoi Ichikawa; Tomohiko Ichikawa
Metastasis suppressor gene(s) for rat prostate cancer on the long arm of human chromosome 7.
Genes, chromosomes & cancer 1999;24(1):1-8.
1998: H Unate; Masahide Ikeguchi; Nobuaki Kaibara; D Okamura; S Nishihara; M Katoh; Mitsuo Oshimura
Telomerase activity and microsatellite instability in colorectal cancer and adenoma.
International journal of oncology 1998;13(6):1223-8.
1998: Hiromi Tanaka; M Shimizu; Izumi Horikawa; Hiroyuki Kugoh; Jun Yokota; J Carl Barrett; Mitsuo Oshimura
Evidence for a putative telomerase repressor gene in the 3p14.2-p21.1 region.
Genes, chromosomes & cancer 1998;23(2):123-33.
1998: Yoshimi Kuroiwa; T Shinohara; T Notsu; Kazuma Tomizuka; Hitoshi Yoshida; S Takeda; Mitsuo Oshimura; Isao Ishida
Efficient modification of a human chromosome by telomere-directed truncation in high homologous recombination-proficient chicken DT40 cells.
Nucleic acids research 1998;26(14):3447-8.
1998: Shinya Matsuura; Hiroshi Tauchi; Asako Nakamura; N Kondo; S Sakamoto; S Endo; Dominique Smeets; B Solder; B H Belohradsky; V M Der Kaloustian; Mitsuo Oshimura; Mariko Isomura; Yusuke Nakamura; Kenshi Komatsu
Positional cloning of the gene for Nijmegen breakage syndrome.
Nature genetics 1998;19(2):179-81.
1998: A Nishimoto; N Miura; Mitsuo Oshimura
[Clinical significance of telomerase activity in precancerous lesion of the liver (adenomatous hyperplasia)].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(5):1244-7.
1998: Mitsuo Oshimura
[Telomerase and cancer].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(5):1136-8.
1998: Mitsuo Oshimura; Hiroyuki Kugoh
[Telomerase repressor genes].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(5):1108-14.
1998: H Uejima; Tokuyuki Shinohara; Y Nakayama; Hiroyuki Kugoh; Mitsuo Oshimura
Mapping a novel cellular-senescence gene to human chromosome 2q37 by irradiation microcell-mediated chromosome transfer.
Molecular carcinogenesis 1998;22(1):34-45.
1998: Kohzoh Mitsuya; Makiko Meguro; H Sui; Thomas C Schulz; Hiroyuki Kugoh; H Hamada; Mitsuo Oshimura
Epigenetic reprogramming of the human H19 gene in mouse embryonic cells does not erase the primary parental imprint.
Genes to cells : devoted to molecular & cellular mechanisms 1998;3(4):245-55.
1998: Kohzoh Mitsuya; Makiko Meguro; Mitsuo Oshimura
[Studies of genomic imprinting using mouse cells containing a human chromosome].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1998;43(4):573-82.
1998: Motonobu Katoh; M Katoh; M Kameyama; Hiroyuki Kugoh; M Shimizu; Mitsuo Oshimura
A repressor function for telomerase activity in telomerase-negative immortal cells.
Molecular carcinogenesis 1998;21(1):17-25.
1997: Takao Matsuda; M Sasaki; Hidenori Kato; H Yamada; M Cohen; J C Barrett; Mitsuo Oshimura; Norio Wake
Human chromosome 7 carries a putative tumor suppressor gene(s) involved in choriocarcinoma.
Oncogene 1997;15(23):2773-81.
1997: Kohzoh Mitsuya; H Sui; Makiko Meguro; Hiroyuki Kugoh; Y Jinno; N Niikawa; Mitsuo Oshimura
Paternal expression of WT1 in human fibroblasts and lymphocytes.
Human molecular genetics 1997;6(13):2243-6.
1997: Makiko Meguro; Kohzoh Mitsuya; H Sui; Katsuyo Shigenami; Hiroyuki Kugoh; M Nakao; Mitsuo Oshimura
Evidence for uniparental, paternal expression of the human GABAA receptor subunit genes, using microcell-mediated chromosome transfer.
Human molecular genetics 1997;6(12):2127-33.
1997: Chiharu Kimura; Naoki Takeda; M Suzuki; Mitsuo Oshimura; Shinichi Aizawa; Isao Matsuo
Cis-acting elements conserved between mouse and pufferfish Otx2 genes govern the expression in mesencephalic neural crest cells.
Development (Cambridge, England) 1997;124(20):3929-41.
1997: Hidehiko Sugino; Mitsuo Oshimura; K Mastubara
Distribution of human endogenous retroviral RTVL-H2 LTR sequences among human chromosomes.
Gene 1997;198(1-2):83-7.
1997: Kaiyo Takubo; Ken-Ichi Nakamura; Naotaka Izumiyama; Ken-ichi Mafune; Y Tanaka; M Miyashita; Koji Sasajima; Motonobu Kato; Mitsuo Oshimura
Telomerase activity in esophageal carcinoma.
Journal of surgical oncology 1997;66(2):88-92.
1997: Shinya Matsuura; Corry M R Weemaes; Dominique Smeets; H Takami; N Kondo; S Sakamoto; N Yano; Asako Nakamura; Hiroshi Tauchi; S Endo; Mitsuo Oshimura; Kenshi Komatsu
Genetic mapping using microcell-mediated chromosome transfer suggests a locus for Nijmegen breakage syndrome at chromosome 8q21-24.
American journal of human genetics 1997;60(6):1487-94.
1997: Kazuma Tomizuka; Hitoshi Yoshida; H Uejima; Hiroyuki Kugoh; K Sato; Atsuko Ohguma; Michiko Hayasaka; K Hanaoka; Mitsuo Oshimura; Isao Ishida
Functional expression and germline transmission of a human chromosome fragment in chimaeric mice.
Nature genetics 1997;16(2):133-43.
1997: Mitsuo Oshimura; J Carl Barrett
Multiple pathways to cellular senescence: role of telomerase repressors.
European journal of cancer (Oxford, England : 1990) 1997;33(5):710-5.
1997: N Miura; Izumi Horikawa; A Nishimoto; H Ohmura; H Ito; S Hirohashi; J W Shay; Mitsuo Oshimura
Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis.
Cancer genetics and cytogenetics 1997;93(1):56-62.
1996: Mitsuo Oshimura; M Shimizu; Hiroyuki Kugoh
Genetic regulation of telomerase in a multiple pathways model to cellular senescence.
Human cell 1996;9(4):301-8.
1996: Kenshi Komatsu; Shinya Matsuura; Hiroshi Tauchi; S Endo; S Kodama; Dominique Smeets; Corry M R Weemaes; Mitsuo Oshimura
The gene for Nijmegen breakage syndrome (V2) is not located on chromosome 11.
American journal of human genetics 1996;58(4):885-8.
1995: Motonobu Katoh; Y Nakagawa; T Yawata; S Kumano; E Kobayashi; Akihiro Kurimasa; Hiroyuki Kugoh; Mitsuo Oshimura
Cosmids and transcribed sequences from chromosome 11q23.
The Japanese journal of human genetics 1995;40(4):307-17.
1995: Izumi Horikawa; A Okamoto; J Yokota; Mitsuo Oshimura
Genetic heterogeneity of chromosome 11 associated with tumorigenicity in HeLa D98-OR cells.
Cancer genetics and cytogenetics 1995;85(2):97-100.
1995: Izumi Horikawa; Mitsuo Oshimura
[Studies on tumor suppressor genes by gene/chromosome transfer].
Nihon rinsho. Japanese journal of clinical medicine 1995;53(11):2647-52.
1995: H Uejima; Kohzoh Mitsuya; Hiroyuki Kugoh; Izumi Horikawa; Mitsuo Oshimura
Normal human chromosome 2 induces cellular senescence in the human cervical carcinoma cell line SiHa.
Genes, chromosomes & cancer 1995;14(2):120-7.
1995: H Ohmura; Hidetoshi Tahara; M Suzuki; T Ide; M Shimizu; M A Yoshida; E Tahara; J W Shay; J Carl Barrett; Mitsuo Oshimura
Restoration of the cellular senescence program and repression of telomerase by human chromosome 3.
Japanese journal of cancer research : Gann 1995;86(10):899-904.
1995: Izumi Horikawa; H Tanaka; Y Yuasa; M Suzuki; M Shimizu; Mitsuo Oshimura
Forced expression of YL-1 protein suppresses the anchorage-independent growth of Kirsten sarcoma virus-transformed NIH3T3 cells.
Experimental cell research 1995;220(1):11-7.
1995: Akihiro Kurimasa; N Suzuki; S Kumano; H Li; D Wells; M J Wagner; F Chen; David J Chen; Mitsuo Oshimura
Construction of 110 cosmid markers and a 4.5-Mb YAC contig on human chromosome 8p12-q11.
Genomics 1995;28(2):147-53.
1995: Izumi Horikawa; H Yamada; Hiroyuki Kugoh; Y Yuasa; M Suzuki; Mitsuo Oshimura
Subchromosomal mapping of a putative transformation suppressor gene on human chromosome 1.
Japanese journal of cancer research : Gann 1995;86(5):444-50.
1995: Hiroyuki Kugoh; Y Nakagawa; Kohzoh Mitsuya; T Mita; M Suzuki; N Suzuki; H Uejima; Y Yuasa; Mitsuo Oshimura
Isolation and mapping of 186 new DNA markers on human chromosome 1.
Genomics 1995;27(1):207-10.
1995: SR Peterson; Akihiro Kurimasa; Mitsuo Oshimura; William S Dynan; E Morton Bradbury; David J Chen
Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3171-4.
1995: Izumi Horikawa; M Suzuki; M A Yoshida; Mitsuo Oshimura
Frame-shift mutation and reduced transcript of p53 gene in a renal cell carcinoma cell line, RCC23.
Human molecular genetics 1995;4(4):771-3.
1995: Izumi Horikawa; H Tanaka; Y Yuasa; M Suzuki; Mitsuo Oshimura
Molecular cloning of a novel human cDNA on chromosome 1q21 and its mouse homolog encoding a nuclear protein with DNA-binding ability.
Biochemical and biophysical research communications 1995;208(3):999-1007.
1995: Izumi Horikawa; M Suzuki; Mitsuo Oshimura
An amino-terminally truncated p53 protein expressed in a human choriocarcinoma cell line, CC1.
Human molecular genetics 1995;4(2):313-4.
1994: M Sasaki; T Honda; H Yamada; N Wake; J C Barrett; Mitsuo Oshimura
Evidence for multiple pathways to cellular senescence.
Cancer research 1994;54(23):6090-3.
1994: Akihiro Kurimasa; Y Nagata; M Shimizu; M Emi; Y Nakamura; Mitsuo Oshimura
A human gene that restores the DNA-repair defect in SCID mice is located on 8p11.1-->q11.1.
Human genetics 1994;93(1):21-6.
1993: Akihiro Kurimasa; K Ohno; Mitsuo Oshimura
Restoration of the cholesterol metabolism in 3T3 cell lines derived from the sphingomyelinosis mouse (spm/spm) by transfer of a human chromosome 18.
Human genetics 1993;92(2):157-62.
1993: H Ohmura; Mitsuo Oshimura
[Telomere, cellular senescence and transformation].
Nihon rinsho. Japanese journal of clinical medicine 1993;51(7):1899-906.
1993: Mitsuo Oshimura; A Kurimasa; M Shimizu
[Use of microcell-hybrid for genomic analyses].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1993;38(3):563-72.
1992: David J Chen; M S Park; E Campbell; Mitsuo Oshimura; P Liu; Y Zhao; B F White; M J Siciliano
Assignment of a human DNA double-strand break repair gene (XRCC5) to chromosome 2.
Genomics 1992;13(4):1088-94.
1992: T Ichikawa; Y Ichikawa; J Dong; Anita L Hawkins; Constance A Griffin; William B Isaacs; Mitsuo Oshimura; J Carl Barrett; John T Isaacs
Localization of metastasis suppressor gene(s) for prostatic cancer to the short arm of human chromosome 11.
Cancer research 1992;52(12):3486-90.
1991: Mitsuo Oshimura
Lessons learned from studies on tumor suppression by microcell-mediated chromosome transfer.
Environmental health perspectives 1991;93():57-8.
1990: Hiroyuki Kugoh; H Hashiba; M Shimizu; Mitsuo Oshimura
Suggestive evidence for functionally distinct, tumor-suppressor genes on chromosomes 1 and 11 for a human fibrosarcoma cell line, HT1080.
Oncogene 1990;5(11):1637-44.
1990: H Yamada; Izumi Horikawa; H Hashiba; Mitsuo Oshimura
Normal human chromosome 1 carries suppressor activity for various phenotypes of a Kirsten murine sarcoma virus-transformed NIH/3T3 cell line.
Japanese journal of cancer research : Gann 1990;81(11):1095-100.
1990: Mitsuo Oshimura; M Shimizu
[Microcell-mediated chromosome transfer--identification of chromosomes carrying a tumor-suppressor function].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1990;35(14):2402-12.
1990: Mitsuo Oshimura; M Shimizu
[Studies on tumor suppressor genes via microcell fusion].
Nihon rinsho. Japanese journal of clinical medicine 1990;48(8):248-54.
1990: Mitsuo Oshimura; Hiroyuki Kugoh; M Koi; M Shimizu; H Yamada; H Satoh; J C Barrett
Transfer of a normal human chromosome 11 suppresses tumorigenicity of some but not all tumor cell lines.
Journal of cellular biochemistry 1990;42(3):135-42.
1990: M Shimizu; J Yokota; N Mori; T Shuin; M Shinoda; M Terada; Mitsuo Oshimura
Introduction of normal chromosome 3p modulates the tumorigenicity of a human renal cell carcinoma cell line YCR.
Oncogene 1990;5(2):185-94.
1989: M Koi; M Shimizu; H Morita; H Yamada; Mitsuo Oshimura
Construction of mouse A9 clones containing a single human chromosome tagged with neomycin-resistance gene via microcell fusion.
Japanese journal of cancer research : Gann 1989;80(5):413-8.
1989: M Koi; H Morita; M Shimizu; Mitsuo Oshimura
Construction of mouse A9 clones containing a single human chromosome (X/autosome translocation) via micro-cell fusion.
Japanese journal of cancer research : Gann 1989;80(2):122-5.
1989: M Koi; H Morita; H Yamada; H Satoh; J C Barrett; Mitsuo Oshimura
Normal human chromosome 11 suppresses tumorigenicity of human cervical tumor cell line SiHa.
Molecular carcinogenesis 1989;2(1):12-21.
1989: Mitsuo Oshimura; Hiroyuki Kugoh; M Shimizu; H Yamada; H Hashiba; Izumi Horikawa; M Sasaki
Multiple chromosomes carrying tumor suppressor activity, via microcell-mediated chromosome transfer, for various tumor cell lines.
Princess Takamatsu symposia 1989;20():249-57.

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