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Mitsuo Oshimura

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Living Beings

Mice

Physiology

Anatomy

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Tumor Suppressor Genes

Chemicals & Drugs

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Publications

TOP 3
Kashiwagi Akiko; Kurosaki Hajime; Luo Hong; Yamamoto Hiroshi; Oshimura Mitsuo; Shibahara Toshiyuki
Effects of Tritrichomonas muris on the mouse intestine: a proteomic analysis.
Lee Jiyoung; Kanatsu-Shinohara Mito; Morimoto Hiroko; Kazuki Yasuhiro; Takashima Seiji; Oshimura Mitsuo; Toyokuni Shinya; Shinohara Takashi
Genetic reconstruction of mouse spermatogonial stem cell self-renewal in vitro by Ras-cyclin D2 activation.
Ariyoshi Kentaro; Suzuki Keiji; Goto Makoto; Oshimura Mitsuo; Ishizaki Kanji; Watanabe Masami; Kodama Seiji
Introduction of a normal human chromosome 8 corrects abnormal phenotypes of Werner syndrome cells immortalized by expressing an hTERT gene.

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All Publications

2009: Kashiwagi Akiko; Kurosaki Hajime; Luo Hong; Yamamoto Hiroshi; Oshimura Mitsuo; Shibahara Toshiyuki
Effects of Tritrichomonas muris on the mouse intestine: a proteomic analysis.
Experimental animals / Japanese Association for Laboratory Animal Science 2009;58(5):537-42.
2009: Lee Jiyoung; Kanatsu-Shinohara Mito; Morimoto Hiroko; Kazuki Yasuhiro; Takashima Seiji; Oshimura Mitsuo; Toyokuni Shinya; Shinohara Takashi
Genetic reconstruction of mouse spermatogonial stem cell self-renewal in vitro by Ras-cyclin D2 activation.
Cell stem cell 2009;5(1):76-86.
2009: Ariyoshi Kentaro; Suzuki Keiji; Goto Makoto; Oshimura Mitsuo; Ishizaki Kanji; Watanabe Masami; Kodama Seiji
Introduction of a normal human chromosome 8 corrects abnormal phenotypes of Werner syndrome cells immortalized by expressing an hTERT gene.
Journal of radiation research 2009;50(3):253-9.
2009: Inoue Toshiaki; Nakayama Yuji; Yamada Hidetoshi; Li Yanze C; Yamaguchi Shigeyuki; Osaki Mitsuhiko; Kurimasa Akihiro; Hiratsuka Masaharu; Katoh Motonobu; Oshimura Mitsuo
SIRT2 downregulation confers resistance to microtubule inhibitors by prolonging chronic mitotic arrest.
Cell cycle (Georgetown, Tex.) 2009;8(8):1279-91.
2009: Kawazoe Shinjirou; Ikeda Nobuhito; Miki Kengo; Shibuya Masayuki; Morikawa Kumi; Nakano Seiji; Oshimura Mitsuo; Hisatome Ichiro; Shirayoshi Yasuaki
Extrinsic factors derived from mouse embryonal carcinoma cell lines maintain pluripotency of mouse embryonic stem cells through a novel signal pathway.
Development, growth & differentiation 2009;51(2):81-93.
2009: Hoshiya Hidetoshi; Kazuki Yasuhiro; Abe Satoshi; Takiguchi Masato; Kajitani Naoyo; Watanabe Yoshinori; Yoshino Toko; Shirayoshi Yasuaki; Higaki Katsumi; Messina Graziella; Cossu Giulio; Oshimura Mitsuo
A highly stable and nonintegrated human artificial chromosome (HAC) containing the 2.4 Mb entire human dystrophin gene.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(2):309-17.
2009: Kai Yoshiteru; Wang Chi Chiu; Kishigami Satoshi; Kazuki Yasuhiro; Abe Satoshi; Takiguchi Masato; Shirayoshi Yasuaki; Inoue Toshiaki; Ito Hisao; Wakayama Teruhiko; Oshimura Mitsuo
Enhanced apoptosis during early neuronal differentiation in mouse ES cells with autosomal imbalance.
Cell research 2009;19(2):247-58.
2009: Murakami K; Ohhira T; Oshiro E; Qi D; Oshimura M; Kugoh H
Identification of the chromatin regions coated by non-coding Xist RNA.
Cytogenetic and genome research 2009;125(1):19-25.
2009: Otsuka Susumu; Maegawa Shinji; Takamura Ayumi; Kamitani Hideki; Watanabe Takashi; Oshimura Mitsuo; Nanba Eiji
Aberrant promoter methylation and expression of the imprinted PEG3 gene in glioma.
Proceedings of the Japan Academy. Series B, Physical and biological sciences 2009;85(4):157-65.
2009: Miura Norimasa; Sato Reina; Tsukamoto Tomoe; Shimizu Mika; Kabashima Hiroko; Takeda Miho; Takahashi Shunsaku; Harada Tomomi; West James E; Drabkin Harry; Mejia Jose E; Shiota Goshi; Murawaki Yoshikazu; Virmani Arvind; Gazdar Adi F; Oshimura Mitsuo; Hasegawa Junichi
A noncoding RNA gene on chromosome 10p15.3 may function upstream of hTERT.
BMC molecular biology 2009;10():5.
2008: Yotova Iveta Y; Vlatkovic Irena M; Pauler Florian M; Warczok Katarzyna E; Ambros Peter F; Oshimura Mitsuo; Theussl Hans-Christian; Gessler Manfred; Wagner Erwin F; Barlow Denise P
Identification of the human homolog of the imprinted mouse Air non-coding RNA.
Genomics 2008;92(6):464-73.
2008: Haugen Astrid C; Goel Ajay; Yamada Kanae; Marra Giancarlo; Nguyen Thuy-Phuong; Nagasaka Takeshi; Kanazawa Shinsaku; Koike Junichi; Kikuchi Yoshinori; Zhong Xiaoling; Arita Michitsune; Shibuya Kazutoshi; Oshimura Mitsuo; Hemmi Hiromichi; Boland C Richard; Koi Minoru
Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer.
Cancer research 2008;68(20):8465-72.
2008: Shibui Takeo; Higo Yukari; Tsutsui Takeo W; Uchida Minoru; Oshimura Mitsuo; Barrett J Carl; Tsutsui Takeki
Changes in expression of imprinted genes following treatment of human cancer cell lines with non-mutagenic or mutagenic carcinogens.
International journal of oncology 2008;33(2):351-60.
2008: Miyano Masaru; Horike Shin-ichi; Cai Shutao; Oshimura Mitsuo; Kohwi-Shigematsu Terumi
DLX5 expression is monoallelic and Dlx5 is up-regulated in the Mecp2-null frontal cortex.
Journal of cellular and molecular medicine 2008;12(4):1188-91.
2008: Nguyen Phuongmai; Cui Hengmi; Bisht Kheem S; Sun Lunching; Patel Krish; Lee Richard S; Kugoh Hiroyuki; Oshimura Mitsuo; Feinberg Andrew P; Gius David
CTCFL/BORIS is a methylation-independent DNA-binding protein that preferentially binds to the paternal H19 differentially methylated region.
Cancer research 2008;68(14):5546-51.
2008: Shitara Shingo; Kakeda Minoru; Nagata Keiko; Hiratsuka Masaharu; Sano Akiko; Osawa Kanako; Okazaki Akiyo; Katoh Motonobu; Kazuki Yasuhiro; Oshimura Mitsuo; Tomizuka Kazuma
Telomerase-mediated life-span extension of human primary fibroblasts by human artificial chromosome (HAC) vector.
Biochemical and biophysical research communications 2008;369(3):807-11.
2008: Kazuki Y; Hoshiya H; Kai Y; Abe S; Takiguchi M; Osaki M; Kawazoe S; Katoh M; Kanatsu-Shinohara M; Inoue K; Kajitani N; Yoshino T; Shirayoshi Y; Ogura A; Shinohara T; Barrett J C; Oshimura M
Correction of a genetic defect in multipotent germline stem cells using a human artificial chromosome.
Gene therapy 2008;15(8):617-24.
2008: Oshimura Mitsuo; Katoh Motonobu
Transfer of human artificial chromosome vectors into stem cells.
Reproductive biomedicine online 2008;16(1):57-69.
2008: Nagahama Yumi; Ishimaru Mika; Osaki Mitsuhiko; Inoue Toshiaki; Maeda Akihiro; Nakada Chisato; Moriyama Masatsugu; Sato Kenzo; Oshimura Mitsuo; Ito Hisao
Apoptotic pathway induced by transduction of RUNX3 in the human gastric carcinoma cell line MKN-1.
Cancer science 2008;99(1):23-30.
2008: Yamada Hidetoshi; Li Yanze C; Nishikawa Mitsuo; Oshimura Mitsuo; Inoue Toshiaki
Introduction of a CD40L genomic fragment via a human artificial chromosome vector permits cell-type-specific gene expression and induces immunoglobulin secretion.
Journal of human genetics 2008;53(5):447-53.
2007: Takehashi Masanori; Kanatsu-Shinohara Mito; Miki Hiromi; Lee Jiyoung; Kazuki Yasuhiro; Inoue Kimiko; Ogonuki Narumi; Toyokuni Shinya; Oshimura Mitsuo; Ogura Atsuo; Shinohara Takashi
Production of knockout mice by gene targeting in multipotent germline stem cells.
Developmental biology 2007;312(1):344-52.
2007: Osaki Mitsuhiko; Inoue Toshiaki; Yamaguchi Shigeyuki; Inaba Aiko; Tokuyasu Naruo; Jeang Kuan-Teh; Oshimura Mitsuo; Ito Hisao
MAD1 (mitotic arrest deficiency 1) is a candidate for a tumor suppressor gene in human stomach.
Virchows Archiv : an international journal of pathology 2007;451(4):771-9.
2007: Nakamura Ken-Ichi; Takubo Kaiyo; Izumiyama-Shimomura Naotaka; Sawabe Motoji; Arai Tomio; Kishimoto Hiroshi; Fujiwara Mutsunori; Kato Motonobu; Oshimura Mitsuo; Ishii Akio; Ishikawa Naoshi
Telomeric DNA length in cerebral gray and white matter is associated with longevity in individuals aged 70 years or older.
Experimental gerontology 2007;42(10):944-50.
2007: Itaba-Matsumoto Noriko; Maegawa Shinji; Yamagata Hidehisa; Kondo Ikuko; Oshimura Mitsuo; Nanba Eiji
Imprinting status of paternally imprinted DLX5 gene in Japanese patients with Rett syndrome.
Brain & development 2007;29(8):491-5.
2007: Mukaida Naoki; Kodama Seiji; Suzuki Keiji; Oshimura Mitsuo; Watanabe Masami
Transmission of genomic instability from a single irradiated human chromosome to the progeny of unirradiated cells.
Radiation research 2007;167(6):675-81.
2007: Inoue Toshiaki; Hiratsuka Masaharu; Osaki Mitsuhiko; Oshimura Mitsuo
The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation.
Cell cycle (Georgetown, Tex.) 2007;6(9):1011-8.
2007: Tomimatsu Nozomi; Tahimic Candice G T; Otsuki Akihiro; Burma Sandeep; Fukuhara Akiko; Sato Kenzo; Shiota Goshi; Oshimura Mitsuo; Chen David J; Kurimasa Akihiro
Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks.
The Journal of biological chemistry 2007;282(14):10138-45.
2007: Kurosaki Hajime; Kazuki Yasuhiro; Hiratsuka Masaharu; Inoue Toshiaki; Matsui Yasuhisa; Wang Chi Chiu; Kanatsu-Shinohara Mito; Shinohara Takashi; Toda Tosifusa; Oshimura Mitsuo
A comparison study in the proteomic signatures of multipotent germline stem cells, embryonic stem cells, and germline stem cells.
Biochemical and biophysical research communications 2007;353(2):259-67.
2007: Kawahara Masahiro; Inoue Toshiaki; Ren Xianying; Sogo Takahiro; Yamada Hidetoshi; Katoh Motonobu; Ueda Hiroshi; Oshimura Mitsuo; Nagamune Teruyuki
Antigen-mediated growth control of hybridoma cells via a human artificial chromosome.
Biochimica et biophysica acta 2007;1770(2):206-12.
2007: Inoue T; Hiratsuka M; Osaki M; Yamada H; Kishimoto I; Yamaguchi S; Nakano S; Katoh M; Ito H; Oshimura M
SIRT2, a tubulin deacetylase, acts to block the entry to chromosome condensation in response to mitotic stress.
Oncogene 2007;26(7):945-57.
2007: Murakami Kazuhiro; Oshimura Mitsuo; Kugoh Hiroyuki
Suggestive evidence for chromosomal localization of non-coding RNA from imprinted LIT1.
Journal of human genetics 2007;52(11):926-33.
2006: Mizuta Einosuke; Furuichi Hitomi; Kazuki Yasuhiro; Miake Junichiro; Yano Shuichi; Bahrudin Udin; Yamamoto Yasutaka; Igawa Osamu; Shigemasa Chiaki; Hidaka Kyoko; Morisaki Takayuki; Kurata Yasutaka; Ninomiya Haruaki; Kitakaze Masafumi; Shirayoshi Yasuaki; Oshimura Mitsuo; Hisatome Ichiro
Delayed onset of beating and decreased expression of T-type Ca2+ channel in mouse ES cell-derived cardiocytes carrying human chromosome 21.
Biochemical and biophysical research communications 2006;351(1):126-32.
2006: Nakano Seiji; Murakami Kazuhiro; Meguro Makiko; Soejima Hidenobu; Higashimoto Ken; Urano Takeshi; Kugoh Hiroyuki; Mukai Tsunehiro; Ikeguchi Masahide; Oshimura Mitsuo
Expression profile of LIT1/KCNQ1OT1 and epigenetic status at the KvDMR1 in colorectal cancers.
Cancer science 2006;97(11):1147-54.
2006: Ishihara Ko; Oshimura Mitsuo; Nakao Mitsuyoshi
CTCF-dependent chromatin insulator is linked to epigenetic remodeling.
Molecular cell 2006;23(5):733-42.
2006: Ishii Akio; Nakamura Ken-Ichi; Kishimoto Hiroshi; Honma Naoko; Aida Junko; Sawabe Motoji; Arai Tomio; Fujiwara Mutsunori; Takeuchi Fujio; Kato Motonobu; Oshimura Mitsuo; Izumiyama Naotaka; Takubo Kaiyo
Telomere shortening with aging in the human pancreas.
Experimental gerontology 2006;41(9):882-6.
2006: Kanatsu-Shinohara Mito; Ikawa Masahito; Takehashi Masanori; Ogonuki Narumi; Miki Hiromi; Inoue Kimiko; Kazuki Yasuhiro; Lee Jiyoung; Toyokuni Shinya; Oshimura Mitsuo; Ogura Atsuo; Shinohara Takashi
Production of knockout mice by random or targeted mutagenesis in spermatogonial stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(21):8018-23.
2006: Ishikawa Yoshinori; Tanaka Nobuyuki; Murakami Kazuhiro; Uchiyama Toru; Kumaki Satoru; Tsuchiya Shigeru; Kugoh Hiroyuki; Oshimura Mitsuo; Calos Michele P; Sugamura Kazuo
Phage phiC31 integrase-mediated genomic integration of the common cytokine receptor gamma chain in human T-cell lines.
The journal of gene medicine 2006;8(5):646-53.
2006: Tahimic Candice Ginn T; Tomimatsu Nozomi; Nishigaki Ryuichi; Fukuhara Akiko; Toda Tosifusa; Kaibuchi Kozo; Shiota Goshi; Oshimura Mitsuo; Kurimasa Akihiro
Evidence for a role of Collapsin response mediator protein-2 in signaling pathways that regulate the proliferation of non-neuronal cells.
Biochemical and biophysical research communications 2006;340(4):1244-50.
2006: Matsuura Shinya; Matsumoto Yoshiyuki; Morishima Ken-ichi; Izumi Hideki; Matsumoto Hiroshi; Ito Emi; Tsutsui Keisuke; Kobayashi Junya; Tauchi Hiroshi; Kajiwara Yoshinori; Hama Seiji; Kurisu Kaoru; Tahara Hidetoshi; Oshimura Mitsuo; Komatsu Kenshi; Ikeuchi Tatsuro; Kajii Tadashi
Monoallelic BUB1B mutations and defective mitotic-spindle checkpoint in seven families with premature chromatid separation (PCS) syndrome.
American journal of medical genetics. Part A 2006;140(4):358-67.
2006: Suda Tetsuji; Katoh Motonobu; Hiratsuka Masaharu; Takiguchi Masato; Kazuki Yasuhiro; Inoue Toshiaki; Oshimura Mitsuo
Heat-regulated production and secretion of insulin from a human artificial chromosome vector.
Biochemical and biophysical research communications 2006;340(4):1053-61.
2006: Ren Xianying; Tahimic Candice Ginn T; Katoh Motonobu; Kurimasa Akihiro; Inoue Toshiaki; Oshimura Mitsuo
Human artificial chromosome vectors meet stem cells: new prospects for gene delivery.
Stem cell reviews 2006;2(1):43-50.
2006: Yamada Hidetoshi; Kunisato Atsushi; Kawahara Masahiro; Tahimic Candice G T; Ren Xianying; Ueda Hiroshi; Nagamune Teruyuki; Katoh Motonobu; Inoue Toshiaki; Nishikawa Mitsuo; Oshimura Mitsuo
Exogenous gene expression and growth regulation of hematopoietic cells via a novel human artificial chromosome.
Journal of human genetics 2006;51(2):147-50.
2005: Ren Xianying; Katoh Motonobu; Hoshiya Hidetoshi; Kurimasa Akihiro; Inoue Toshiaki; Ayabe Fumiaki; Shibata Kotaro; Toguchida Junya; Oshimura Mitsuo
A novel human artificial chromosome vector provides effective cell lineage-specific transgene expression in human mesenchymal stem cells.
Stem cells (Dayton, Ohio) 2005;23(10):1608-16.
2005: Yanagisawa Ayano; Endo Chisato; Okawa Katsuya; Shitara Shingo; Kugoh Hiroyuki; Kakitani Makoto; Oshimura Mitsuo; Tomizuka Kazuma
Generation of chromosome-specific monoclonal antibodies using in vitro-differentiated transchromosomic mouse embryonic stem cells.
Stem cells (Dayton, Ohio) 2005;23(10):1479-88.
2005: Kanatsu-Shinohara Mito; Ogonuki Narumi; Iwano Tomohiko; Lee Jiyoung; Kazuki Yasuhiro; Inoue Kimiko; Miki Hiromi; Takehashi Masanori; Toyokuni Shinya; Shinkai Yoichi; Oshimura Mitsuo; Ishino Fumitoshi; Ogura Atsuo; Shinohara Takashi
Genetic and epigenetic properties of mouse male germline stem cells during long-term culture.
Development (Cambridge, England) 2005;132(18):4155-63.
2005: Nishigaki Ryuichi; Osaki Mitsuhiko; Hiratsuka Masaharu; Toda Tosifusa; Murakami Kaori; Jeang Kuan-Teh; Ito Hisao; Inoue Toshiaki; Oshimura Mitsuo
Proteomic identification of differentially-expressed genes in human gastric carcinomas.
Proteomics 2005;5(12):3205-13.
2005: Tanaka Hiromi; Horikawa Izumi; Barrett J Carl; Oshimura Mitsuo
Evidence for inactivation of distinct telomerase repressor genes in different types of human cancers.
International journal of cancer. Journal international du cancer 2005;115(4):653-7.
2005: Kakeda M; Hiratsuka M; Nagata K; Kuroiwa Y; Kakitani M; Katoh M; Oshimura M; Tomizuka K
Human artificial chromosome (HAC) vector provides long-term therapeutic transgene expression in normal human primary fibroblasts.
Gene therapy 2005;12(10):852-6.
2005: Yasui Wataru; Oshimura Mitsuo; Igarashi Kazuhiko; Ito Hisao; Tahara Eiichi
Cancer and epigenetics--basic research and clinical implications: Joint Meeting of the Fourteenth International Symposium of the Hiroshima Cancer Seminar and the Eighth Meeting of the Tottori Bioscience Promotion Foundation, October 2004.
Cancer science 2005;96(4):245-8.
2005: Otsuki Akihiro; Tahimic Candice G T; Tomimatsu Nozomi; Katoh Motonobu; Chen David J; Kurimasa Akihiro; Oshimura Mitsuo
Construction of a novel expression system on a human artificial chromosome.
Biochemical and biophysical research communications 2005;329(3):1018-25.
2005: Yang Lichun; Leung Alfred C C; Ko Josephine M Y; Lo Paulisally H Y; Tang Johnny C O; Srivastava Gopesh; Oshimura Mitsuo; Stanbridge Eric J; Daigo Yataro; Nakamura Yusuke; Tang Cecilia M C; Lau Kwok W; Law Simon; Lung Maria L
Tumor suppressive role of a 2.4 Mb 9q33-q34 critical region and DEC1 in esophageal squamous cell carcinoma.
Oncogene 2005;24(4):697-705.
2005: Kobayashi Daisuke; Ieiri Ichiro; Hirota Takeshi; Takane Hiroshi; Maegawa Shinji; Kigawa Junzo; Suzuki Hiroshi; Nanba Eiji; Oshimura Mitsuo; Terakawa Naoki; Otsubo Kenji; Mine Kazunori; Sugiyama Yuichi
Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(1):94-101.
2005: Ayabe Fumiaki; Katoh Motonobu; Inoue Toshiaki; Kouprina Natalay; Larionov Vladimir; Oshimura Mitsuo
A novel expression system for genomic DNA loci using a human artificial chromosome vector with transformation-associated recombination cloning.
Journal of human genetics 2005;50(11):592-9.
2005: Spence Jennifer M; Fournier R E Keith; Oshimura Mitsuo; Regnier Vinciane; Farr Christine J
Topoisomerase II cleavage activity within the human D11Z1 and DXZ1 alpha-satellite arrays.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2005;13(6):637-48.
2005: Arima Takahiro; Kamikihara Tetsuya; Hayashida Toshirou; Kato Kiyoko; Inoue Toshiaki; Shirayoshi Yasuaki; Oshimura Mitsuo; Soejima Hidenobu; Mukai Tunehiro; Wake Norio
ZAC, LIT1 (KCNQ1OT1) and p57KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith-Wiedemann syndrome.
Nucleic acids research 2005;33(8):2650-60.
2005: Haruta Masayuki; Meguro Makiko; Sakamoto Yu-ki; Hoshiya Hidetoshi; Kashiwagi Akiko; Kaneko Yasuhiko; Mitsuya Kohzoh; Oshimura Mitsuo
Narrowed abrogation of the Angelman syndrome critical interval on human chromosome 15 does not interfere with epigenotype maintenance in somatic cells.
Journal of human genetics 2005;50(3):124-32.
2004: Kanatsu-Shinohara Mito; Inoue Kimiko; Lee Jiyoung; Yoshimoto Momoko; Ogonuki Narumi; Miki Hiromi; Baba Shiro; Kato Takeo; Kazuki Yasuhiro; Toyokuni Shinya; Toyoshima Megumi; Niwa Ohtsura; Oshimura Mitsuo; Heike Toshio; Nakahata Tatsutoshi; Ishino Fumitoshi; Ogura Atsuo; Shinohara Takashi
Generation of pluripotent stem cells from neonatal mouse testis.
Cell 2004;119(7):1001-12.
2004: Nakanishi Hirofumi; Suda Tetsuji; Katoh Motonobu; Watanabe Akiko; Igishi Tadashi; Kodani Masahiro; Matsumoto Shingo; Nakamoto Masaki; Shigeoka Yasushi; Okabe Tetsuro; Oshimura Mitsuo; Shimizu Eiji
Loss of imprinting of PEG1/MEST in lung cancer cell lines.
Oncology reports 2004;12(6):1273-8.
2004: Hirota Takeshi; Ieiri Ichiro; Takane Hiroshi; Maegawa Shinji; Hosokawa Masakiyo; Kobayashi Kaoru; Chiba Kan; Nanba Eiji; Oshimura Mitsuo; Sato Tetsuo; Higuchi Shun; Otsubo Kenji
Allelic expression imbalance of the human CYP3A4 gene and individual phenotypic status.
Human molecular genetics 2004;13(23):2959-69.
2004: Torisu Hiroyuki; Yamamoto Toshiyuki; Fujiwaki Takehisa; Kadota Mitsutaka; Oshimura Mitsuo; Kurosawa Kenji; Akaboshi Shinjiro; Oka Akira
Girl with monosomy 1p36 and Angelman syndrome due to unbalanced der(1) transmission of a maternal translocation t(1;15)(p36.3;q13.1).
American journal of medical genetics. Part A 2004;131(1):94-8.
2004: Niemitz Emily L; DeBaun Michael R; Fallon Jonathan; Murakami Kazuhiro; Kugoh Hiroyuki; Oshimura Mitsuo; Feinberg Andrew P
Microdeletion of LIT1 in familial Beckwith-Wiedemann syndrome.
American journal of human genetics 2004;75(5):844-9.
2004: Murakami Kaori; Nishigaki Ryuichi; Kazuki Yasuhiro; Kadota Mitsutaka; Oshimura Mitsuo
[Proteomics and epigenetics learned from Down syndrome model mouse]
Seikagaku. The Journal of Japanese Biochemical Society 2004;76(10):1296-304.
2004: Horibata Katsuyoshi; Iwamoto Yuka; Kuraoka Isao; Jaspers Nicolaas G J; Kurimasa Akihiro; Oshimura Mitsuo; Ichihashi Masamitsu; Tanaka Kiyoji
Complete absence of Cockayne syndrome group B gene product gives rise to UV-sensitive syndrome but not Cockayne syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(43):15410-5.
2004: Yu Wenqiang; Ginjala Vasudeva; Pant Vinod; Chernukhin Igor; Whitehead Joanne; Docquier France; Farrar Dawn; Tavoosidana Gholamreza; Mukhopadhyay Rituparna; Kanduri Chandrasekhar; Oshimura Mitsuo; Feinberg Andrew P; Lobanenkov Victor; Klenova Elena; Ohlsson Rolf
Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation.
Nature genetics 2004;36(10):1105-10.
2004: Yamanaka Sumitaka; Sunamura Makoto; Furukawa Toru; Sun Libo; Lefter Liviu P; Abe Tadayoshi; Yatsuoka Toshimasa; Fujimura Hiroko; Shibuya Emiko; Kotobuki Noriko; Oshimura Mitsuo; Sakurada Akira; Sato Masami; Kondo Takashi; Matsuno Seiki; Horii Akira
Chromosome 12, frequently deleted in human pancreatic cancer, may encode a tumor-suppressor gene that suppresses angiogenesis.
Laboratory investigation; a journal of technical methods and pathology 2004;84(10):1339-51.
2004: Lefter Liviu; Scripcaru Viorel; Sunamura Makoto; Furukawa Toru; Matsuno Seiki; Oshimura Mitsuo; Drug Vasile; Dragomir Cristian; Horii Akira
Screening for functional tumor suppressor activity in pancreatic cancer.
Romanian journal of gastroenterology 2004;13(3):195-201.
2004: Osaki M; Moriyama M; Adachi K; Nakada C; Takeda A; Inoue Y; Adachi H; Sato K; Oshimura M; Ito H
Expression of RUNX3 protein in human gastric mucosa, intestinal metaplasia and carcinoma.
European journal of clinical investigation 2004;34(9):605-12.
2004: Katoh Motonobu; Ayabe Fumiaki; Norikane Satoko; Okada Teruaki; Masumoto Hiroshi; Horike Shin-ichi; Shirayoshi Yasuaki; Oshimura Mitsuo
Construction of a novel human artificial chromosome vector for gene delivery.
Biochemical and biophysical research communications 2004;321(2):280-90.
2004: Nakabayashi K; Makino S; Minagawa S; Smith A C; Bamforth J S; Stanier P; Preece M; Parker-Katiraee L; Paton T; Oshimura M; Mill P; Yoshikawa Y; Hui C C; Monk D; Moore G E; Scherer S W
Genomic imprinting of PPP1R9A encoding neurabin I in skeletal muscle and extra-embryonic tissues.
Journal of medical genetics 2004;41(8):601-8.
2004: Fukagawa Tatsuo; Nogami Masahiro; Yoshikawa Mitsuko; Ikeno Masashi; Okazaki Tuneko; Takami Yasunari; Nakayama Tatsuo; Oshimura Mitsuo
Dicer is essential for formation of the heterochromatin structure in vertebrate cells.
Nature cell biology 2004;6(8):784-91.
2004: Soejima Hidenobu; Nakagawachi Tetsuji; Zhao Wei; Higashimoto Ken; Urano Takeshi; Matsukura Shiroh; Kitajima Yoshihiko; Takeuchi Makoto; Nakayama Masahiro; Oshimura Mitsuo; Miyazaki Kohji; Joh Keiichiro; Mukai Tsunehiro
Silencing of imprinted CDKN1C gene expression is associated with loss of CpG and histone H3 lysine 9 methylation at DMR-LIT1 in esophageal cancer.
Oncogene 2004;23(25):4380-8.
2004: Sunamura Makoto; Lefter Liviu P; Duda Dan G; Morita Rina; Inoue Hiroko; Yokoyama Tadaaki; Yatsuoka Toshimasa; Abe Tadayoshi; Egawa Shinichi; Furukawa Toru; Fukushige Shinichi; Oshimura Mitsuo; Horii Akira; Matsuno Seiki
The role of chromosome 18 abnormalities in the progression of pancreatic adenocarcinoma.
Pancreas 2004;28(3):311-6.
2004: Kazuki Yasuhiro; Kimura Motoshi; Nishigaki Ryuichi; Kai Yoshiteru; Abe Satoshi; Okita Chiga; Shirayoshi Yasuaki; Schulz Thomas C; Tomizuka Kazuma; Hanaoka Kazunori; Inoue Toshiaki; Oshimura Mitsuo
Human chromosome 21q22.2-qter carries a gene(s) responsible for downregulation of mlc2a and PEBP in Down syndrome model mice.
Biochemical and biophysical research communications 2004;317(2):491-9.
2004: Nakamura Yuki; Tajima Fumihito; Ishiga Kiyomi; Yamazaki Hidetoshi; Oshimura Mitsuo; Shiota Goshi; Murawaki Yoshikazu
Soluble c-kit receptor mobilizes hematopoietic stem cells to peripheral blood in mice.
Experimental hematology 2004;32(4):390-6.
2004: Yamada Takahiro; Mitsuya Kohzoh; Kayashima Tomohiko; Yamasaki Kentaro; Ohta Tohru; Yoshiura Koh-ichiro; Matsumoto Naomichi; Yamada Hideto; Minakami Hisanori; Oshimura Mitsuo; Niikawa Norio; Kishino Tatsuya
Imprinting analysis of 10 genes and/or transcripts in a 1.5-Mb MEST-flanking region at human chromosome 7q32.
Genomics 2004;83(3):402-12.
2004: Maegawa Shinji; Itaba Noriko; Otsuka Susumu; Kamitani Hideki; Watanabe Takashi; Tahimic Candice G T; Nanba Eiji; Oshimura Mitsuo
Coordinate downregulation of a novel imprinted transcript ITUP1 with PEG3 in glioma cell lines.
DNA research : an international journal for rapid publication of reports on genes and genomes 2004;11(1):37-49.
2004: Wang Chi Chiu; Kadota Mitsutaka; Nishigaki Ryuichi; Kazuki Yasuhiro; Shirayoshi Yasuaki; Rogers Michael Scott; Gojobori Takashi; Ikeo Kazuho; Oshimura Mitsuo
Molecular hierarchy in neurons differentiated from mouse ES cells containing a single human chromosome 21.
Biochemical and biophysical research communications 2004;314(2):335-50.
2004: Kadota M; Nishigaki R; Wang C C; Toda T; Shirayoshi Y; Inoue T; Gojobori T; Ikeo K; Rogers M S; Oshimura M
Proteomic signatures and aberrations of mouse embryonic stem cells containing a single human chromosome 21 in neuronal differentiation: an in vitro model of Down syndrome.
Neuroscience 2004;129(2):325-35.
2004: Kimura Motoshi I; Kazuki Yasuhiro; Kashiwagi Akiko; Kai Yoshiteru; Abe Satoshi; Barbieri Ottavia; Levi Giovanni; Oshimura Mitsuo
Dlx5, the mouse homologue of the human-imprinted DLX5 gene, is biallelically expressed in the mouse brain.
Journal of human genetics 2004;49(5):273-7.
2003: Kamino Hiroki; Hiratsuka Masaharu; Toda Tosifusa; Nishigaki Ryuichi; Osaki Mitsuhiko; Ito Hisao; Inoue Toshiaki; Oshimura Mitsuo
Searching for genes involved in arteriosclerosis: proteomic analysis of cultured human umbilical vein endothelial cells undergoing replicative senescence.
Cell structure and function 2003;28(6):495-503.
2003: Lefter Liviu P; Sunamura Makoto; Furukawa Toru; Takeda Kazunori; Kotobuki Noriko; Oshimura Mitsuo; Matsuno Seiki; Horii Akira
Inserting chromosome 18 into pancreatic cancer cells switches them to a dormant metastatic phenotype.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(13):5044-52.
2003: Higashimoto Ken; Urano Takeshi; Sugiura Kazumitsu; Yatsuki Hitomi; Joh Keiichiro; Zhao Wei; Iwakawa Mayumi; Ohashi Hirofumi; Oshimura Mitsuo; Niikawa Norio; Mukai Tsunehiro; Soejima Hidenobu
Loss of CpG methylation is strongly correlated with loss of histone H3 lysine 9 methylation at DMR-LIT1 in patients with Beckwith-Wiedemann syndrome.
American journal of human genetics 2003;73(4):948-56.
2003: Hiratsuka Masaharu; Inoue Toshiaki; Toda Tosifusa; Kimura Narimichi; Shirayoshi Yasuaki; Kamitani Hideki; Watanabe Takashi; Ohama Eisaku; Tahimic Candice G T; Kurimasa Akihiro; Oshimura Mitsuo
Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene.
Biochemical and biophysical research communications 2003;309(3):558-66.
2003: Fujii Satoshi; Luo Robert Z; Yuan Jiuhong; Kadota Mitsutaka; Oshimura Mitsuo; Dent Sharon R; Kondo Yutaka; Issa Jean-Pierre J; Bast Robert C; Yu Yinhua
Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation.
Human molecular genetics 2003;12(15):1791-800.
2003: Suda Tetsuji; Katoh Motonobu; Hiratsuka Masaharu; Fujiwara Mutsunori; Irizawa Yoshito; Oshimura Mitsuo
Use of real-time RT-PCR for the detection of allelic expression of an imprinted gene.
International journal of molecular medicine 2003;12(2):243-6.
2003: Yuan Jiuhong; Luo Robert Z; Fujii Satoshi; Wang Lin; Hu Wei; Andreeff Michael; Pan Yong; Kadota Mitsutaka; Oshimura Mitsuo; Sahin Aysegul A; Issa Jean-Pierre; Bast Robert C; Yu Yinhua
Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.
Cancer research 2003;63(14):4174-80.
2003: Nikaido Itoshi; Saito Chika; Mizuno Yosuke; Meguro Makiko; Bono Hidemasa; Kadomura Moritoshi; Kono Tomohiro; Morris Gerard A; Lyons Paul A; Oshimura Mitsuo; Hayashizaki Yoshihide; Okazaki Yasushi;
Discovery of imprinted transcripts in the mouse transcriptome using large-scale expression profiling.
Genome research 2003;13(6B):1402-9.
2003: Okita Chiga; Meguro Makiko; Hoshiya Hidetoshi; Haruta Masayuki; Sakamoto Yu-ki; Oshimura Mitsuo
A new imprinted cluster on the human chromosome 7q21-q31, identified by human-mouse monochromosomal hybrids.
Genomics 2003;81(6):556-9.
2003: Yu Yinhua; Fujii Satoshi; Yuan Jiuhong; Luo Robert Z; Wang Lin; Bao Jiaju; Kadota Mitsutaka; Oshimura Mitsuo; Dent Sharon R; Issa Jean-Pierre; Bast Robert C
Epigenetic regulation of ARHI in breast and ovarian cancer cells.
Annals of the New York Academy of Sciences 2003;983():268-77.
2003: Jouvenot Y; Ginjala V; Zhang L; Liu P-Q; Oshimura M; Feinberg A P; Wolffe A P; Ohlsson Rolf; Gregory P D
Targeted regulation of imprinted genes by synthetic zinc-finger transcription factors.
Gene therapy 2003;10(6):513-22.
2003: Yawata Toshio; Kamino Hiroki; Kugoh Hiroyuki; Katoh Motonobu; Nomura Nobuo; Oishi Michio; Horikawa Izumi; Barrett J Carl; Oshimura Mitsuo
Identification of a </= 600-kb region on human chromosome 1q42.3 inducing cellular senescence.
Oncogene 2003;22(2):281-90.
2003: Kugoh Hiroyuki; Shigenami Katsuyo; Funaki Kenji; Barrett J Carl; Oshimura Mitsuo
Human chromosome 5 carries a putative telomerase repressor gene.
Genes, chromosomes & cancer 2003;36(1):37-47.
2003: Kazuki Y; Schulz T C; Shinohara T; Kadota M; Nishigaki R; Inoue T; Kimura M; Kai Y; Abe S; Shirayoshi Y; Oshimura M
A new mouse model for Down syndrome.
Journal of neural transmission. Supplementum 2003;(67):1-20.
2003: Hoshiya Hidetoshi; Meguro Makiko; Kashiwagi Akiko; Okita Chiga; Oshimura Mitsuo
Calcr, a brain-specific imprinted mouse calcitonin receptor gene in the imprinted cluster of the proximal region of chromosome 6.
Journal of human genetics 2003;48(4):208-11.
2003: Kashiwagi Akiko; Meguro Makiko; Hoshiya Hidetoshi; Haruta Masayuki; Ishino Fumitoshi; Shibahara Toshiyuki; Oshimura Mitsuo
Predominant maternal expression of the mouse Atp10c in hippocampus and olfactory bulb.
Journal of human genetics 2003;48(4):194-8.
2002: Kadota Mitsutaka; Shirayoshi Yasuaki; Oshimura Mitsuo
Elevated apoptosis in pre-mature neurons differentiated from mouse ES cells containing a single human chromosome 21.
Biochemical and biophysical research communications 2002;299(4):599-605.
2002: Nakamura Ken-Ichi; Izumiyama-Shimomura Naotaka; Sawabe Motoji; Arai Tomio; Aoyagi Yukitoshi; Fujiwara Mutsunori; Tsuchiya Eiju; Kobayashi Yasuhito; Kato Motonobu; Oshimura Mitsuo; Sasajima Koji; Nakachi Kei; Takubo Kaiyo
Comparative analysis of telomere lengths and erosion with age in human epidermis and lingual epithelium.
The Journal of investigative dermatology 2002;119(5):1014-9.
2002: Feinberg Andrew P; Oshimura Mitsuo; Barrett J Carl
Epigenetic mechanisms in human disease.
Cancer research 2002;62(22):6784-7.
2002: Kugoh Hiroyuki; Nakamoto Hiroko; Inoue Jun; Funaki Kenji; Barrett J Carl; Oshimura Mitsuo
Multiple human chromosomes carrying tumor-suppressor functions for the mouse melanoma cell line B16-F10, identified by microcell-mediated chromosome transfer.
Molecular carcinogenesis 2002;35(3):148-56.
2002: Hori Naohiro; Nakano Hiroshi; Takeuchi Toshiyuki; Kato Hiroyuki; Hamaguchi Sayuri; Oshimura Mitsuo; Sato Kenzo
A dyad oct-binding sequence functions as a maintenance sequence for the unmethylated state within the H19/Igf2-imprinted control region.
The Journal of biological chemistry 2002;277(31):27960-7.
2002: Nakabayashi Kazuhiko; Bentley Louise; Hitchins Megan P; Mitsuya Kohzoh; Meguro Makiko; Minagawa Sachi; Bamforth John S; Stanier Philip; Preece Michael; Weksberg Rosanna; Oshimura Mitsuo; Moore Gudrun E; Scherer Stephen W
Identification and characterization of an imprinted antisense RNA (MESTIT1) in the human MEST locus on chromosome 7q32.
Human molecular genetics 2002;11(15):1743-56.
2002: Nishigaki Ryuichi; Shinohara Tokuyuki; Toda Tosifusa; Omori Akira; Ichinose Sachiyo; Itoh Masayuki; Shirayoshi Yasuaki; Kurimasa Akihiro; Oshimura Mitsuo
An extra human chromosome 21 reduces mlc-2a expression in chimeric mice and Down syndrome.
Biochemical and biophysical research communications 2002;295(1):112-8.
2002: Hosoki Shigeru; Ota Sho; Ichikawa Yayoi; Suzuki Hiroyoshi; Ueda Takeshi; Naya Yukio; Akakura Koichiro; Igarashi Tatsuo; Oshimura Mitsuo; Nihei Naoki; Barrett J Carl; Ichikawa Tomohiko; Ito Haruo
Suppression of metastasis of rat prostate cancer by introduction of human chromosome 13.
Asian journal of andrology 2002;4(2):131-6.
2002: Sekiya Takashi; Nakamura Tsutomu; Kazuki Yasuhiro; Oshimura Mitsuo; Kohu Kazuyoshi; Tago Ken-Ichi; Ohwada Susumu; Akiyama Tetsu
Overexpression of Icat induces G(2) arrest and cell death in tumor cell mutants for adenomatous polyposis coli, beta-catenin, or Axin.
Cancer research 2002;62(11):3322-6.
2002: Kuroiwa Y; Yoshida H; Ohshima T; Shinohara T; Ohguma A; Kazuki Y; Oshimura M; Ishida I; Tomizuka K
The use of chromosome-based vectors for animal transgenesis.
Gene therapy 2002;9(11):708-12.
2002: Lefter Liviu P; Furukawa Toru; Sunamura Makoto; Duda Dan G; Takeda Kazunori; Kotobuki Noriko; Oshimura Mitsuo; Matsuno Seiki; Horii Akira
Suppression of the tumorigenic phenotype by chromosome 18 transfer into pancreatic cancer cell lines.
Genes, chromosomes & cancer 2002;34(2):234-42.
2002: Takubo Kaiyo; Izumiyama-Shimomura Naotaka; Honma Naoko; Sawabe Motoji; Arai Tomio; Kato Motonobu; Oshimura Mitsuo; Nakamura Ken-Ichi
Telomere lengths are characteristic in each human individual.
Experimental gerontology 2002;37(4):523-31.
2002: Nakabayashi Kazuhiko; Fernandez Bridget A; Teshima Ikuko; Shuman Cheryl; Proud Virginia K; Curry Cynthia J; Chitayat David; Grebe Theresa; Ming Jeffrey; Oshimura Mitsuo; Meguro Makiko; Mitsuya Kohzoh; Deb-Rinker Paromita; Herbrick Jo-Anne; Weksberg Rosanna; Scherer Stephen W
Molecular genetic studies of human chromosome 7 in Russell-Silver syndrome.
Genomics 2002;79(2):186-96.
2002: Mizuno Yosuke; Sotomaru Yusuke; Katsuzawa Yukiko; Kono Tomohiro; Meguro Makiko; Oshimura Mitsuo; Kawai Jun; Tomaru Yasuhiro; Kiyosawa Hidenori; Nikaido Itoshi; Amanuma Hiroshi; Hayashizaki Yoshihide; Okazaki Yasushi
Asb4, Ata3, and Dcn are novel imprinted genes identified by high-throughput screening using RIKEN cDNA microarray.
Biochemical and biophysical research communications 2002;290(5):1499-505.
2001: Kohda M; Hoshiya H; Katoh M; Tanaka I; Masuda R; Takemura T; Fujiwara M; Oshimura M
Frequent loss of imprinting of IGF2 and MEST in lung adenocarcinoma.
Molecular carcinogenesis 2001;31(4):184-91.
2001: Arima T; Drewell R A; Arney K L; Inoue J; Makita Y; Hata A; Oshimura M; Wake N; Surani M A
A conserved imprinting control region at the HYMAI/ZAC domain is implicated in transient neonatal diabetes mellitus.
Human molecular genetics 2001;10(14):1475-83.
2001: Maegawa S; Yoshioka H; Itaba N; Kubota N; Nishihara S; Shirayoshi Y; Nanba E; Oshimura M
Epigenetic silencing of PEG3 gene expression in human glioma cell lines.
Molecular carcinogenesis 2001;31(1):1-9.
2001: Shinohara T; Tomizuka K; Miyabara S; Takehara S; Kazuki Y; Inoue J; Katoh M; Nakane H; Iino A; Ohguma A; Ikegami S; Inokuchi K; Ishida I; Reeves R H; Oshimura M
Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Down's syndrome.
Human molecular genetics 2001;10(11):1163-75.
2001: Sakatani T; Wei M; Katoh M; Okita C; Wada D; Mitsuya K; Meguro M; Ikeguchi M; Ito H; Tycko B; Oshimura M
Epigenetic heterogeneity at imprinted loci in normal populations.
Biochemical and biophysical research communications 2001;283(5):1124-30.
2001: Meguro M; Kashiwagi A; Mitsuya K; Nakao M; Kondo I; Saitoh S; Oshimura M
A novel maternally expressed gene, ATP10C, encodes a putative aminophospholipid translocase associated with Angelman syndrome.
Nature genetics 2001;28(1):19-20.
2001: Nishimoto A; Miura N; Horikawa I; Kugoh H; Murakami Y; Hirohashi S; Kawasaki H; Gazdar A F; Shay J W; Barrett J C; Oshimura M
Functional evidence for a telomerase repressor gene on human chromosome 10p15.1.
Oncogene 2001;20(7):828-35.
2001: Meguro M; Mitsuya K; Nomura N; Kohda M; Kashiwagi A; Nishigaki R; Yoshioka H; Nakao M; Oishi M; Oshimura M
Large-scale evaluation of imprinting status in the Prader-Willi syndrome region: an imprinted direct repeat cluster resembling small nucleolar RNA genes.
Human molecular genetics 2001;10(4):383-94.
2001: Yoshioka H; Shirayoshi Y; Oshimura M
A novel in vitro system for analyzing parental allele-specific histone acetylation in genomic imprinting.
Journal of human genetics 2001;46(11):626-32.
2001: Kazuki Y; Shinohara T; Tomizuka K; Katoh M; Ohguma A; Ishida I; Oshimura M
Germline transmission of a transferred human chromosome 21 fragment in transchromosomal mice.
Journal of human genetics 2001;46(10):600-3.
2001: Tanaka K; Shiota G; Meguro M; Mitsuya K; Oshimura M; Kawasaki H
Loss of imprinting of long QT intronic transcript 1 in colorectal cancer.
Oncology 2001;60(3):268-73.
2001: Inoue J; Mitsuya K; Maegawa S; Kugoh H; Kadota M; Okamura D; Shinohara T; Nishihara S; Takehara S; Yamauchi K; Schulz T C; Oshimura M
Construction of 700 human/mouse A9 monochromosomal hybrids and analysis of imprinted genes on human chromosome 6.
Journal of human genetics 2001;46(3):137-45.
2000: Takubo K; Nakamura K; Izumiyama N; Furugori E; Sawabe M; Arai T; Esaki Y; Mafune K; Kammori M; Fujiwara M; Kato M; Oshimura M; Sasajima K
Telomere shortening with aging in human liver.
The journals of gerontology. Series A, Biological sciences and medical sciences 2000;55(11):B533-6.
2000: Taga M; Shiraishi K; Shimura T; Uematsu N; Oshimura M; Niwa O
Increased frequencies of gene and chromosome mutations after X-irradiation in mouse embryonal carcinoma cells transfected with the bcl-2 gene.
Japanese journal of cancer research : Gann 2000;91(10):994-1000.
2000: Kuroiwa Y; Tomizuka K; Shinohara T; Kazuki Y; Yoshida H; Ohguma A; Yamamoto T; Tanaka S; Oshimura M; Ishida I
Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts.
Nature biotechnology 2000;18(10):1086-90.
2000: Nakamura K; Furugori E; Esaki Y; Arai T; Sawabe M; Okayasu I; Fujiwara M; Kammori M; Mafune K; Kato M; Oshimura M; Sasajima K; Takubo K
Correlation of telomere lengths in normal and cancers tissue in the large bowel.
Cancer letters 2000;158(2):179-84.
2000: Ichikawa T; Hosoki S; Suzuki H; Akakura K; Igarashi T; Furuya Y; Oshimura M; Rinker-Schaeffer C W; Nihei N; Barrett J C; Isaacs J T; Ito H
Mapping of metastasis suppressor genes for prostate cancer by microcell-mediated chromosome transfer.
Asian journal of andrology 2000;2(3):167-71.
2000: Taga M; Shiraishi K; Shimura T; Uematsu N; Kato T; Nishimune Y; Aizawa S; Oshimura M; Niwa O
The effect of caffeine on p53-dependent radioresponses in undifferentiated mouse embryonal carcinoma cells after X-ray and UV-irradiations.
Journal of radiation research 2000;41(3):227-41.
2000: Horike S; Mitsuya K; Meguro M; Kotobuki N; Kashiwagi A; Notsu T; Schulz T C; Shirayoshi Y; Oshimura M
Targeted disruption of the human LIT1 locus defines a putative imprinting control element playing an essential role in Beckwith-Wiedemann syndrome.
Human molecular genetics 2000;9(14):2075-83.
2000: Arima T; Drewell R A; Oshimura M; Wake N; Surani M A
A novel imprinted gene, HYMAI, is located within an imprinted domain on human chromosome 6 containing ZAC.
Genomics 2000;67(3):248-55.
2000: Nishihara S; Hayashida T; Mitsuya K; Schulz T C; Ikeguchi M; Kaibara N; Oshimura M
Multipoint imprinting analysis in sporadic colorectal cancers with and without microsatellite instability.
International journal of oncology 2000;17(2):317-22.
2000: Inoue T; Shinohara T; Takehara S; Inoue J; Kamino H; Kugoh H; Oshimura M
Specific impairment of cardiogenesis in mouse ES cells containing a human chromosome 21.
Biochemical and biophysical research communications 2000;273(1):219-24.
2000: Kugoh H; Fujiwara M; Kihara K; Fukui I; Horikawa I; Schulz T C; Oshimura M
Cellular senescence of a human bladder carcinoma cell line (JTC-32) induced by a normal chromosome 11.
Cancer genetics and cytogenetics 2000;116(2):158-63.
2000: Tomizuka K; Shinohara T; Yoshida H; Uejima H; Ohguma A; Tanaka S; Sato K; Oshimura M; Ishida I
Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(2):722-7.
2000: Shinohara T; Tomizuka K; Takehara S; Yamauchi K; Katoh M; Ohguma A; Ishida I; Oshimura M
Stability of transferred human chromosome fragments in cultured cells and in mice.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2000;8(8):713-25.
1999: Tanaka H; Horikawa I; Kugoh H; Shimizu M; Barrett J C; Oshimura M
Telomerase-independent senescence of human immortal cells induced by microcell-mediated chromosome transfer.
Molecular carcinogenesis 1999;25(4):249-55.
1999: Mitsuya K; Meguro M; Lee M P; Katoh M; Schulz T C; Kugoh H; Yoshida M A; Niikawa N; Feinberg A P; Oshimura M
LIT1, an imprinted antisense RNA in the human KvLQT1 locus identified by screening for differentially expressed transcripts using monochromosomal hybrids.
Human molecular genetics 1999;8(7):1209-17.
1999: Kugoh H; Mitsuya K; Meguro M; Shigenami K; Schulz T C; Oshimura M
Mouse A9 cells containing single human chromosomes for analysis of genomic imprinting.
DNA research : an international journal for rapid publication of reports on genes and genomes 1999;6(3):165-72.
1999: Lee M P; DeBaun M R; Mitsuya K; Galonek H L; Brandenburg S; Oshimura M; Feinberg A P
Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5203-8.
1999: Nihei N; Ohta S; Kuramochi H; Kugoh H; Oshimura M; Barrett J C; Isaacs J T; Igarashi T; Ito H; Masai M; Ichikawa Y; Ichikawa T
Metastasis suppressor gene(s) for rat prostate cancer on the long arm of human chromosome 7.
Genes, chromosomes & cancer 1999;24(1):1-8.
1998: Unate H; Ikeguchi M; Kaibara N; Okamura D; Nishihara S; Katoh M; Oshimura M
Telomerase activity and microsatellite instability in colorectal cancer and adenoma.
International journal of oncology 1998;13(6):1223-8.
1998: Tanaka H; Shimizu M; Horikawa I; Kugoh H; Yokota J; Barrett J C; Oshimura M
Evidence for a putative telomerase repressor gene in the 3p14.2-p21.1 region.
Genes, chromosomes & cancer 1998;23(2):123-33.
1998: Kuroiwa Y; Shinohara T; Notsu T; Tomizuka K; Yoshida H; Takeda S; Oshimura M; Ishida I
Efficient modification of a human chromosome by telomere-directed truncation in high homologous recombination-proficient chicken DT40 cells.
Nucleic acids research 1998;26(14):3447-8.
1998: Matsuura S; Tauchi H; Nakamura A; Kondo N; Sakamoto S; Endo S; Smeets D; Solder B; Belohradsky B H; Der Kaloustian V M; Oshimura M; Isomura M; Nakamura Y; Komatsu K
Positional cloning of the gene for Nijmegen breakage syndrome.
Nature genetics 1998;19(2):179-81.
1998: Nishimoto A; Miura N; Oshimura M
[Clinical significance of telomerase activity in precancerous lesion of the liver (adenomatous hyperplasia)]
Nippon rinsho. Japanese journal of clinical medicine 1998;56(5):1244-7.
1998: Oshimura M
[Telomerase and cancer]
Nippon rinsho. Japanese journal of clinical medicine 1998;56(5):1136-8.
1998: Oshimura M; Kugoh H
[Telomerase repressor genes]
Nippon rinsho. Japanese journal of clinical medicine 1998;56(5):1108-14.
1998: Uejima H; Shinohara T; Nakayama Y; Kugoh H; Oshimura M
Mapping a novel cellular-senescence gene to human chromosome 2q37 by irradiation microcell-mediated chromosome transfer.
Molecular carcinogenesis 1998;22(1):34-45.
1998: Mitsuya K; Meguro M; Sui H; Schulz T C; Kugoh H; Hamada H; Oshimura M
Epigenetic reprogramming of the human H19 gene in mouse embryonic cells does not erase the primary parental imprint.
Genes to cells : devoted to molecular & cellular mechanisms 1998;3(4):245-55.
1998: Mitsuya K; Meguro M; Oshimura M
[Studies of genomic imprinting using mouse cells containing a human chromosome]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1998;43(4):573-82.
1998: Katoh M; Katoh M; Kameyama M; Kugoh H; Shimizu M; Oshimura M
A repressor function for telomerase activity in telomerase-negative immortal cells.
Molecular carcinogenesis 1998;21(1):17-25.
1997: Matsuda T; Sasaki M; Kato H; Yamada H; Cohen M; Barrett J C; Oshimura M; Wake N
Human chromosome 7 carries a putative tumor suppressor gene(s) involved in choriocarcinoma.
Oncogene 1997;15(23):2773-81.
1997: Mitsuya K; Sui H; Meguro M; Kugoh H; Jinno Y; Niikawa N; Oshimura M
Paternal expression of WT1 in human fibroblasts and lymphocytes.
Human molecular genetics 1997;6(13):2243-6.
1997: Meguro M; Mitsuya K; Sui H; Shigenami K; Kugoh H; Nakao M; Oshimura M
Evidence for uniparental, paternal expression of the human GABAA receptor subunit genes, using microcell-mediated chromosome transfer.
Human molecular genetics 1997;6(12):2127-33.
1997: Kimura C; Takeda N; Suzuki M; Oshimura M; Aizawa S; Matsuo I
Cis-acting elements conserved between mouse and pufferfish Otx2 genes govern the expression in mesencephalic neural crest cells.
Development (Cambridge, England) 1997;124(20):3929-41.
1997: Sugino H; Oshimura M; Mastubara K
Distribution of human endogenous retroviral RTVL-H2 LTR sequences among human chromosomes.
Gene 1997;198(1-2):83-7.
1997: Takubo K; Nakamura K; Izumiyama N; Mafune K; Tanaka Y; Miyashita M; Sasajima K; Kato M; Oshimura M
Telomerase activity in esophageal carcinoma.
Journal of surgical oncology 1997;66(2):88-92.
1997: Matsuura S; Weemaes C; Smeets D; Takami H; Kondo N; Sakamoto S; Yano N; Nakamura A; Tauchi H; Endo S; Oshimura M; Komatsu K
Genetic mapping using microcell-mediated chromosome transfer suggests a locus for Nijmegen breakage syndrome at chromosome 8q21-24.
American journal of human genetics 1997;60(6):1487-94.
1997: Tomizuka K; Yoshida H; Uejima H; Kugoh H; Sato K; Ohguma A; Hayasaka M; Hanaoka K; Oshimura M; Ishida I
Functional expression and germline transmission of a human chromosome fragment in chimaeric mice.
Nature genetics 1997;16(2):133-43.
1997: Oshimura M; Barrett J C
Multiple pathways to cellular senescence: role of telomerase repressors.
European journal of cancer (Oxford, England : 1990) 1997;33(5):710-5.
1997: Miura N; Horikawa I; Nishimoto A; Ohmura H; Ito H; Hirohashi S; Shay J W; Oshimura M
Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis.
Cancer genetics and cytogenetics 1997;93(1):56-62.
1996: Oshimura M; Shimizu M; Kugoh H
Genetic regulation of telomerase in a multiple pathways model to cellular senescence.
Human cell : official journal of Human Cell Research Society 1996;9(4):301-8.
1996: Komatsu K; Matsuura S; Tauchi H; Endo S; Kodama S; Smeets D; Weemaes C; Oshimura M
The gene for Nijmegen breakage syndrome (V2) is not located on chromosome 11.
American journal of human genetics 1996;58(4):885-8.
1995: Katoh M; Nakagawa Y; Yawata T; Kumano S; Kobayashi E; Kurimasa A; Kugoh H; Oshimura M
Cosmids and transcribed sequences from chromosome 11q23.
The Japanese journal of human genetics 1995;40(4):307-17.
1995: Horikawa I; Okamoto A; Yokota J; Oshimura M
Genetic heterogeneity of chromosome 11 associated with tumorigenicity in HeLa D98-OR cells.
Cancer genetics and cytogenetics 1995;85(2):97-100.
1995: Horikawa I; Oshimura M
[Studies on tumor suppressor genes by gene/chromosome transfer]
Nippon rinsho. Japanese journal of clinical medicine 1995;53(11):2647-52.
1995: Uejima H; Mitsuya K; Kugoh H; Horikawa I; Oshimura M
Normal human chromosome 2 induces cellular senescence in the human cervical carcinoma cell line SiHa.
Genes, chromosomes & cancer 1995;14(2):120-7.
1995: Ohmura H; Tahara H; Suzuki M; Ide T; Shimizu M; Yoshida M A; Tahara E; Shay J W; Barrett J C; Oshimura M
Restoration of the cellular senescence program and repression of telomerase by human chromosome 3.
Japanese journal of cancer research : Gann 1995;86(10):899-904.
1995: Horikawa I; Tanaka H; Yuasa Y; Suzuki M; Shimizu M; Oshimura M
Forced expression of YL-1 protein suppresses the anchorage-independent growth of Kirsten sarcoma virus-transformed NIH3T3 cells.
Experimental cell research 1995;220(1):11-7.
1995: Kurimasa A; Suzuki N; Kumano S; Li H; Wells D; Wagner M J; Chen F; Chen D J; Oshimura M
Construction of 110 cosmid markers and a 4.5-Mb YAC contig on human chromosome 8p12-q11.
Genomics 1995;28(2):147-53.
1995: Horikawa I; Yamada H; Kugoh H; Yuasa Y; Suzuki M; Oshimura M
Subchromosomal mapping of a putative transformation suppressor gene on human chromosome 1.
Japanese journal of cancer research : Gann 1995;86(5):444-50.
1995: Kugoh H; Nakagawa Y; Mitsuya K; Mita T; Suzuki M; Suzuki N; Uejima H; Yuasa Y; Oshimura M
Isolation and mapping of 186 new DNA markers on human chromosome 1.
Genomics 1995;27(1):207-10.
1995: Peterson S R; Kurimasa A; Oshimura M; Dynan W S; Bradbury E M; Chen D J
Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3171-4.
1995: Horikawa I; Suzuki M; Yoshida M A; Oshimura M
Frame-shift mutation and reduced transcript of p53 gene in a renal cell carcinoma cell line, RCC23.
Human molecular genetics 1995;4(4):771-3.
1995: Horikawa I; Tanaka H; Yuasa Y; Suzuki M; Oshimura M
Molecular cloning of a novel human cDNA on chromosome 1q21 and its mouse homolog encoding a nuclear protein with DNA-binding ability.
Biochemical and biophysical research communications 1995;208(3):999-1007.
1995: Horikawa I; Suzuki M; Oshimura M
An amino-terminally truncated p53 protein expressed in a human choriocarcinoma cell line, CC1.
Human molecular genetics 1995;4(2):313-4.
1994: Sasaki M; Honda T; Yamada H; Wake N; Barrett J C; Oshimura M
Evidence for multiple pathways to cellular senescence.
Cancer research 1994;54(23):6090-3.
1994: Kurimasa A; Nagata Y; Shimizu M; Emi M; Nakamura Y; Oshimura M
A human gene that restores the DNA-repair defect in SCID mice is located on 8p11.1-->q11.1.
Human genetics 1994;93(1):21-6.
1993: Kurimasa A; Ohno K; Oshimura M
Restoration of the cholesterol metabolism in 3T3 cell lines derived from the sphingomyelinosis mouse (spm/spm) by transfer of a human chromosome 18.
Human genetics 1993;92(2):157-62.
1993: Ohmura H; Oshimura M
[Telomere, cellular senescence and transformation]
Nippon rinsho. Japanese journal of clinical medicine 1993;51(7):1899-906.
1993: Oshimura M; Kurimasa A; Shimizu M
[Use of microcell-hybrid for genomic analyses]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1993;38(3):563-72.
1992: Chen D J; Park M S; Campbell E; Oshimura M; Liu P; Zhao Y; White B F; Siciliano M J
Assignment of a human DNA double-strand break repair gene (XRCC5) to chromosome 2.
Genomics 1992;13(4):1088-94.
1992: Ichikawa T; Ichikawa Y; Dong J; Hawkins A L; Griffin C A; Isaacs W B; Oshimura M; Barrett J C; Isaacs J T
Localization of metastasis suppressor gene(s) for prostatic cancer to the short arm of human chromosome 11.
Cancer research 1992;52(12):3486-90.
1991: Oshimura M
Lessons learned from studies on tumor suppression by microcell-mediated chromosome transfer.
Environmental health perspectives 1991;93():57-8.
1990: Kugoh H M; Hashiba H; Shimizu M; Oshimura M
Suggestive evidence for functionally distinct, tumor-suppressor genes on chromosomes 1 and 11 for a human fibrosarcoma cell line, HT1080.
Oncogene 1990;5(11):1637-44.
1990: Yamada H; Horikawa I; Hashiba H; Oshimura M
Normal human chromosome 1 carries suppressor activity for various phenotypes of a Kirsten murine sarcoma virus-transformed NIH/3T3 cell line.
Japanese journal of cancer research : Gann 1990;81(11):1095-100.
1990: Oshimura M; Shimizu M
[Microcell-mediated chromosome transfer--identification of chromosomes carrying a tumor-suppressor function]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1990;35(14):2402-12.
1990: Oshimura M; Shimizu M
[Studies on tumor suppressor genes via microcell fusion]
Nippon rinsho. Japanese journal of clinical medicine 1990;48(8):248-54.
1990: Oshimura M; Kugoh H; Koi M; Shimizu M; Yamada H; Satoh H; Barrett J C
Transfer of a normal human chromosome 11 suppresses tumorigenicity of some but not all tumor cell lines.
Journal of cellular biochemistry 1990;42(3):135-42.
1990: Shimizu M; Yokota J; Mori N; Shuin T; Shinoda M; Terada M; Oshimura M
Introduction of normal chromosome 3p modulates the tumorigenicity of a human renal cell carcinoma cell line YCR.
Oncogene 1990;5(2):185-94.
1989: Koi M; Shimizu M; Morita H; Yamada H; Oshimura M
Construction of mouse A9 clones containing a single human chromosome tagged with neomycin-resistance gene via microcell fusion.
Japanese journal of cancer research : Gann 1989;80(5):413-8.
1989: Koi M; Morita H; Shimizu M; Oshimura M
Construction of mouse A9 clones containing a single human chromosome (X/autosome translocation) via micro-cell fusion.
Japanese journal of cancer research : Gann 1989;80(2):122-5.
1989: Koi M; Morita H; Yamada H; Satoh H; Barrett J C; Oshimura M
Normal human chromosome 11 suppresses tumorigenicity of human cervical tumor cell line SiHa.
Molecular carcinogenesis 1989;2(1):12-21.
1989: Oshimura M; Kugoh H M; Shimizu M; Yamada H; Hashiba H; Horikawa I; Sasaki M
Multiple chromosomes carrying tumor suppressor activity, via microcell-mediated chromosome transfer, for various tumor cell lines.
Princess Takamatsu symposia 1989;20():249-57.

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