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Bohdan Ostash

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Publications

TOP 3
Bohdan Ostash; Emma Doud; Suzanne Walker
ABC transporter genes from Streptomyces ghanaensis moenomycin biosynthetic gene cluster: roles in antibiotic production and export.
Lilia Horbal; Bohdan Ostash; Sergiy Shulga; Nestor Zaburannyy; Victor Fedorenko
Manipulating the regulatory genes for teicoplanin production in Actinoplanes teichomyceticus.
Mariia Rabyk; Yuriy Rebets; Suzanne Walker; Bohdan Ostash; Victor Fedorenko
Streptomyces ghanaensis pleiotropic regulatory gene wblA(gh) influences morphogenesis and moenomycin production.

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All Publications

2012: Bohdan Ostash; Emma Doud; Suzanne Walker
ABC transporter genes from Streptomyces ghanaensis moenomycin biosynthetic gene cluster: roles in antibiotic production and export.
Archives of microbiology 2012;194(11):915-22.
2012: Lilia Horbal; Bohdan Ostash; Sergiy Shulga; Nestor Zaburannyy; Victor Fedorenko
Manipulating the regulatory genes for teicoplanin production in Actinoplanes teichomyceticus.
World journal of microbiology & biotechnology 2012;28(5):2095-100.
2011: Mariia Rabyk; Yuriy Rebets; Suzanne Walker; Bohdan Ostash; Victor Fedorenko
Streptomyces ghanaensis pleiotropic regulatory gene wblA(gh) influences morphogenesis and moenomycin production.
Biotechnology letters 2011;33(12):2481-6.
2011: Bohdan Ostash; Iryna Ostash; Yuriy Rebets; Olga Tsypik; Suzanne Walker; Yuriy Datsyuk; Oleksandr Kulachkovskyy; Maksym Myronovskyy; Tatsunosuke Nakamura; Victor Fedorenko
Identification and characterization of the Streptomyces globisporus 1912 regulatory gene lndYR that affects sporulation and antibiotic production.
Microbiology (Reading, England) 2011;157(Pt 4):1240-9.
2010: Bohdan Ostash; Suzanne Walker
Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity.
Natural product reports 2010;27(11):1594-617.
2010: Wenjun Zhang; Bohdan Ostash; Christopher T Walsh
Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(39):16828-33.
2010: Roman Makitrynskyy; Yuriy Rebets; Bohdan Ostash; Nestor Zaburannyi; Mariia Rabyk; Suzanne Walker; Victor Fedorenko
Genetic factors that influence moenomycin production in streptomycetes.
Journal of industrial microbiology & biotechnology 2010;37(6):559-66.
2010: Bohdan Ostash; I Ostash; L Zhu; M K Kharel; A Luzhetskiĭ; Andreas Bechthold; S Walker; Jürgen Rohr; Victor Fedorenko
Properties of lanK-based regulatory circuit involved in landomycin biosynthesis in Streptomyces cyanogenus S136.
Genetika 2010;46(5):604-9.
2010: Bohdan Ostash; Emma Doud; Victor Fedorenko
The molecular biology of moenomycins: towards novel antibiotics based on inhibition of bacterial peptidoglycan glycosyltransferases.
Biological chemistry 2010;391(5):499-504.
2010: Bohdan Ostash; Xiaohui Yan; Victor Fedorenko; Andreas Bechthold
Chemoenzymatic and bioenzymatic synthesis of carbohydrate containing natural products.
Topics in current chemistry 2010;297():105-48.
2009: Bohdan Ostash; Emma H Doud; Cecilie Lin; Iryna Ostash; Deborah L Perlstein; Shinichiro Fuse; Manuel Wolpert; Daniel Kahne; Suzanne Walker
Complete characterization of the seventeen step moenomycin biosynthetic pathway.
Biochemistry 2009;48(37):8830-41.
2009: Nestor Zaburannyy; Bohdan Ostash; Victor Fedorenko
TTA Lynx: a web-based service for analysis of actinomycete genes containing rare TTA codon.
Bioinformatics (Oxford, England) 2009;25(18):2432-3.
2009: Bohdan Ostash; Roman Makitrinskyy; Suzanne Walker; Victor Fedorenko
Identification and characterization of Streptomyces ghanaensis ATCC14672 integration sites for three actinophage-based plasmids.
Plasmid 2009;61(3):171-5.
2009: M Myronovskyy; Bohdan Ostash; I Ostash; Victor Fedorenko
A gene cloning system for the siomycin producer Streptomyces sioyaensis NRRL-B5408.
Folia microbiologica 2009;54(2):91-6.
2008: Iryna Ostash; Bohdan Ostash; Andriy Luzhetskyy; Andreas Bechthold; Suzanne Walker; Victor Fedorenko
Coordination of export and glycosylation of landomycins in Streptomyces cyanogenus S136.
FEMS microbiology letters 2008;285(2):195-202.
2008: Yanqiu Yuan; Shinichiro Fuse; Bohdan Ostash; Piotr Sliz; Daniel Kahne; Suzanne Walker
Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for antibiotic design.
ACS chemical biology 2008;3(7):429-36.
2008: Iryna Ostash; Yuriy Rebets; Bohdan Ostash; Anton Kobylyanskyy; Maksym Myronovskyy; Tatsunosuke Nakamura; Suzanne Walker; Victor Fedorenko
An ABC transporter encoding gene lndW confers resistance to landomycin E.
Archives of microbiology 2008;190(1):105-9.
2008: Yuriy Rebets; Lilia Dutko; Bohdan Ostash; Andriy Luzhetskyy; Olexandr Kulachkovskyy; Toshio Yamaguchi; Tatsunosuke Nakamura; Andreas Bechthold; Victor Fedorenko
Function of lanI in regulation of landomycin A biosynthesis in Streptomyces cyanogenus S136 and cross-complementation studies with Streptomyces antibiotic regulatory proteins encoding genes.
Archives of microbiology 2008;189(2):111-20.
2007: I Ostash; Bohdan Ostash; S Walker; Victor Fedorenko
Proton-dependent transporter gene lndJ confers resistance to landomycin E in Streptomyces globisporus.
Genetika 2007;43(8):1032-7.
2007: Bohdan Ostash; Alan Saghatelian; Suzanne Walker
A streamlined metabolic pathway for the biosynthesis of moenomycin A.
Chemistry & biology 2007;14(3):257-67.
2006: Irfan Baig; Madan Kumar Kharel; Anton Kobylyanskyy; Lili Zhu; Yuriy Rebets; Bohdan Ostash; Andriy Luzhetskyy; Andreas Bechthold; Victor A Fedorenko; Jürgen Rohr
On the acceptor substrate of C-glycosyltransferase UrdGT2: three prejadomycin C-Glycosides from an engineered mutant of Streptomyces globisporus 1912 DeltalndE(urdGT2).
Angewandte Chemie (International ed. in English) 2006;45(46):7842-6.
2006: Andriy Luzhetskyy; Marta Fedoryshyn; Oleksandr Gromyko; Bohdan Ostash; Yuriy Rebets; Andreas Bechthold; Victor Fedorenko
IncP plasmids are most effective in mediating conjugation between Escherichia coli and streptomycetes.
Genetika 2006;42(5):595-601.
2006: Yuriy Rebets; Bohdan Ostash; Masahiro Fukuhara; Tatsunosuke Nakamura; Victor Fedorenko
Expression of the regulatory protein LndI for landomycin E production in Streptomyces globisporus 1912 is controlled by the availability of tRNA for the rare UUA codon.
FEMS microbiology letters 2006;256(1):30-7.
2006: Lilia Dutko; Yuriy Rebets; Bohdan Ostash; Andriy Luzhetskyy; Andreas Bechthold; Tatsunosuke Nakamura; Victor Fedorenko
A putative proteinase gene is involved in regulation of landomycin E biosynthesis in Streptomyces globisporus 1912.
FEMS microbiology letters 2006;255(2):280-5.
2005: Bohdan Ostash; Suzanne Walker
Bacterial transglycosylase inhibitors.
Current opinion in chemical biology 2005;9(5):459-66.
2005: Andriy Luzhetskyy; Lili Zhu; Miranda Gibson; Marta Fedoryshyn; Clemens Dürr; Carsten Hofmann; Dirk Hoffmeister; Bohdan Ostash; Cynthia Mattingly; Val Adams; Victor Fedorenko; Jürgen Rohr; Andreas Bechthold
Generation of novel landomycins M and O through targeted gene disruption.
Chembiochem : a European journal of chemical biology 2005;6(4):675-8.
2005: Lili Zhu; Bohdan Ostash; Uwe Rix; Mohammad Nur-e-Alam; Almuth Mayers; Andriy Luzhetskyy; Carmen Mendez; José A Salas; Andreas Bechthold; Victor Fedorenko; Jürgen Rohr
Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycinone.
The Journal of organic chemistry 2005;70(2):631-8.
2005: Bohdan Ostash; I Kozarevska; Victor Fedorenko
Generation of landomycin D-producing strain Streptomyces globisporus LD3.
Folia microbiologica 2005;50(1):19-23.
2005: Yuriy Rebets; Bohdan Ostash; Andriy Luzhetskyy; S Kushnir; Masahiro Fukuhara; Andreas Bechthold; M Nashimoto; Tatsunosuke Nakamura; Victor Fedorenko
DNA-binding activity of LndI protein and temporal expression of the gene that upregulates landomycin E production in Streptomyces globisporus 1912.
Microbiology (Reading, England) 2005;151(Pt 1):281-90.
2004: Andriy Luzhetskyy; Tao Liu; Marta Fedoryshyn; Bohdan Ostash; Victor Fedorenko; Jürgen Rohr; Andreas Bechthold
Function of lanGT3, a glycosyltransferase gene involved in landomycin A biosynthesis.
Chembiochem : a European journal of chemical biology 2004;5(11):1567-70.
2004: Oleksandr Gromyko; Yuriy Rebets; Bohdan Ostash; Andriy Luzhetskyy; Masahiro Fukuhara; Andreas Bechthold; Tatsunosuke Nakamura; Victor Fedorenko
Generation of Streptomyces globisporus SMY622 strain with increased landomycin E production and it's initial characterization.
The Journal of antibiotics 2004;57(6):383-9.
2004: Bohdan Ostash; Uwe Rix; Lily L Remsing Rix; Tao Liu; Felipe Lombo; Andriy Luzhetskyy; Oleksandr Gromyko; Chenchen Wang; Alfredo F Braña; Carmen Méndez; José A Salas; Victor Fedorenko; Jürgen Rohr
Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus.
Chemistry & biology 2004;11(4):547-55.
2003: Yuriy Rebets; Bohdan Ostash; Andriy Luzhetskyy; Dirk Hoffmeister; A Brana; Carmen Mendez; José A Salas; Andreas Bechthold; Victor Fedorenko
Production of landomycins in Streptomyces globisporus 1912 and S cyanogenus S136 is regulated by genes encoding putative transcriptional activators.
FEMS microbiology letters 2003;222(1):149-53.
2003: Bohdan Ostash; Yuriy Rebets; V Yuskevich; Andriy Luzhetskyy; V Tkachenko; Victor Fedorenko
Targeted disruption of Streptomyces globisporus lndF and lndL cyclase genes involved in landomycin E biosynthesis.
Folia microbiologica 2003;48(4):484-8.