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Stefan Oswald

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TOP 3
Anett Engel; Stefan Oswald; Werner Siegmund; Markus Keiser
Pharmaceutical excipients influence the function of human uptake transporting proteins.
Ali Nassif; Stefan Oswald; Werner Siegmund; Werner Weitschies; Norbert Hosten; Jia Jia; Markus Keiser; Christiane Modess; Stefan Nagel; Jens-Peter Kühn
Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging.
Karen Saljé; Eike Dazert; Kirstin Lederer; Stefan Oswald; Rolf Warzok; Werner Siegmund
Effects of rifampicin, dexamethasone, St. John's Wort and Thyroxine on maternal and foetal expression of Abcb1 and organ distribution of talinolol in pregnant rats.

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All Publications

2012: Anett Engel; Stefan Oswald; Werner Siegmund; Markus Keiser
Pharmaceutical excipients influence the function of human uptake transporting proteins.
Molecular pharmaceutics 2012;9(9):2577-81.
2012: Ali Nassif; Stefan Oswald; Werner Siegmund; Werner Weitschies; Norbert Hosten; Jia Jia; Markus Keiser; Christiane Modess; Stefan Nagel; Jens-Peter Kühn
Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging.
Radiology 2012;264(3):741-50.
2012: Karen Saljé; Eike Dazert; Kirstin Lederer; Stefan Oswald; Rolf Warzok; Werner Siegmund
Effects of rifampicin, dexamethasone, St. John's Wort and Thyroxine on maternal and foetal expression of Abcb1 and organ distribution of talinolol in pregnant rats.
Basic & clinical pharmacology & toxicology 2012;111(2):99-105.
2012: Henriette Meyer zu Schwabedissen; Christiane Modess; A Nassif; M Nauck; E T Ogburn; Stefan Oswald; C Bresser; Z Desta; Heyo K Kroemer; Dieter Lütjohann; M Marinova; C Spielhagen; Werner Siegmund
Compartment-specific gene regulation of the CAR inducer efavirenz in vivo.
Clinical pharmacology and therapeutics 2012;92(1):103-11.
2012: Nicole Mähler; Bärbel Miehe; Stefan Oswald; Rainer Rettig; Torsten Schlüter; Antje Steinbach; Martin Freyer; Rene Kauschke; Alexander Krebs; Olaf Grisk
Kidney-specific deletion of multidrug resistance-related protein 2 does not aggravate acute cyclosporine A nephrotoxicity in rats.
Pharmacogenetics and genomics 2012;22(6):408-20.
2012: Jia Jia; Markus Keiser; Ali Nassif; Werner Siegmund; Stefan Oswald
A LC-MS/MS method to evaluate the hepatic uptake of the liver-specific magnetic resonance imaging contrast agent gadoxetate (Gd-EOB-DTPA) in vitro and in humans.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2012;891-892():20-6.
2012: Stefan Oswald; D Runge; A Ulrich; Z Desta; A Hubeny; J Jia; M Keiser; Heyo K Kroemer; Dieter Lütjohann; M Marinova; Henriette Meyer zu Schwabedissen; Christiane Modess; Jörg Mostertz; A Nassif; E T Ogburn; Werner Siegmund
Impact of efavirenz on intestinal metabolism and transport: insights from an interaction study with ezetimibe in healthy volunteers.
Clinical pharmacology and therapeutics 2012;91(3):506-13.
2012: Jette Peters; Monica Venner; Wiebke Block; Karen Eggers; Marc Lämmer; Dieter Lütjohann; Stefan Oswald; Werner Siegmund
Clarithromycin is absorbed by an intestinal uptake mechanism that is sensitive to major inhibition by rifampicin: results of a short-term drug interaction study in foals.
Drug metabolism and disposition: the biological fate of chemicals 2012;40(3):522-8.
2011: Stefan Oswald; Gitta Schumacher; Werner Siegmund
Quantitative determination of methylnaltrexone in human serum using liquid chromatography-tandem mass spectrometry.
Journal of pharmaceutical and biomedical analysis 2011;56(5):1079-84.
2011: Jette Peters; Monica Venner; Wiebke Block; Johanna Freyer; Markus Grube; Heyo K Kroemer; Marc Lämmer; Dieter Lütjohann; Stefan Oswald; Werner Siegmund
Oral absorption of clarithromycin is nearly abolished by chronic comedication of rifampicin in foals.
Drug metabolism and disposition: the biological fate of chemicals 2011;39(9):1643-9.
2011: Stefan Oswald; A Nassif; Christiane Modess; M Keiser; A Ulrich; D Runge; U Hanke; Dieter Lütjohann; A Engel; Werner Weitschies; Werner Siegmund
Drug interactions between the immunosuppressant tacrolimus and the cholesterol absorption inhibitor ezetimibe in healthy volunteers.
Clinical pharmacology and therapeutics 2011;89(4):524-8.
2011: Stefan Oswald; Bernd Terhaag; Werner Siegmund
In vivo probes of drug transport: commonly used probe drugs to assess function of intestinal P-glycoprotein (ABCB1) in humans.
Handbook of experimental pharmacology 2011;(201):403-47.
2010: Mirko Leonhardt; Markus Keiser; Stefan Oswald; Jens Kühn; Jia Jia; Markus Grube; Heyo K Kroemer; Werner Siegmund; Werner Weitschies
Hepatic uptake of the magnetic resonance imaging contrast agent Gd-EOB-DTPA: role of human organic anion transporters.
Drug metabolism and disposition: the biological fate of chemicals 2010;38(7):1024-8.
2010: Stefan Oswald; A Nassif; Christiane Modess; M Keiser; U Hanke; A Engel; Dieter Lütjohann; Werner Weitschies; Werner Siegmund
Pharmacokinetic and pharmacodynamic interactions between the immunosuppressant sirolimus and the lipid-lowering drug ezetimibe in healthy volunteers.
Clinical pharmacology and therapeutics 2010;87(6):663-7.
2010: Stefan Oswald; Karen May; Juliane Rosin; Dieter Lütjohann; Werner Siegmund
Synergistic influence of Abcb1 and Abcc2 on disposition and sterol lowering effects of ezetimibe in rats.
Journal of pharmaceutical sciences 2010;99(1):422-9.
2009: Juliane Niessen; Gabriele Jedlitschky; Markus Grube; Sandra Bien; Hansjörg Schwertz; Sumio Ohtsuki; Hirotaka Kawakami; Junichi Kamiie; Stefan Oswald; Katharina Starke; Ulrike Strobel; Werner Siegmund; Dieter Rosskopf; Andreas Greinacher; Tetsuya Terasaki; Heyo K Kroemer
Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(5):1129-37.
2008: Karen May; Thomas Giessmann; Danilo Wegner; Reinhard Oertel; Christiane Modess; Stefan Oswald; Manfred Braeter; Werner Siegmund
Oral absorption of propiverine solution and of the immediate and extended release dosage forms: influence of regioselective intestinal elimination.
European journal of clinical pharmacology 2008;64(11):1085-92.
2008: Stefan Oswald; Jörg König; Dieter Lütjohann; Thomas Giessmann; Heyo K Kroemer; Christian Rimmbach; Dieter Rosskopf; Martin F Fromm; Werner Siegmund
Disposition of ezetimibe is influenced by polymorphisms of the hepatic uptake carrier OATP1B1.
Pharmacogenetics and genomics 2008;18(7):559-68.
2007: Stefan Oswald; Christiane Koll; Werner Siegmund
Disposition of the cholesterol absorption inhibitor ezetimibe in mdr1a/b (-/-) mice.
Journal of pharmaceutical sciences 2007;96(12):3478-84.
2007: Stefan Oswald; Markus Grube; Werner Siegmund; Heyo K Kroemer
Transporter-mediated uptake into cellular compartments.
Xenobiotica; the fate of foreign compounds in biological systems 2007;37(10-11):1171-95.
2006: Markus Grube; Kathleen Köck; Stefan Oswald; Katrin Draber; Konrad Meissner; Lothar Eckel; Michael Böhm; Stephan B Felix; Silke Vogelgesang; Gabriele Jedlitschky; Werner Siegmund; Rolf Warzok; Heyo K Kroemer
Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart.
Clinical pharmacology and therapeutics 2006;80(6):607-20.
2006: Stefan Oswald; Thomas Giessmann; Dieter Luetjohann; Danilo Wegner; Dieter Rosskopf; Werner Weitschies; Werner Siegmund
Disposition and sterol-lowering effect of ezetimibe are influenced by single-dose coadministration of rifampin, an inhibitor of multidrug transport proteins.
Clinical pharmacology and therapeutics 2006;80(5):477-85.
2006: Stefan Oswald; Sabine Westrup; Markus Grube; Heyo K Kroemer; Werner Weitschies; Werner Siegmund
Disposition and sterol-lowering effect of ezetimibe in multidrug resistance-associated protein 2-deficient rats.
The Journal of pharmacology and experimental therapeutics 2006;318(3):1293-9.
2006: Stefan Oswald; Sierk Haenisch; Christiane Fricke; Thomas Sudhop; Cornelia Remmler; Thomas Giessmann; Gabriele Jedlitschky; Ulrike Adam; Eike Dazert; Rolf Warzok; Wolfram Wacke; Ingolf Cascorbi; Heyo K Kroemer; Werner Weitschies; Klaus Von Bergmann; Werner Siegmund
Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetimibe in humans.
Clinical pharmacology and therapeutics 2006;79(3):206-17.
2006: Stefan Oswald; Eberhard Scheuch; Ingolf Cascorbi; Werner Siegmund
A LC-MS/MS method to quantify the novel cholesterol lowering drug ezetimibe in human serum, urine and feces in healthy subjects genotyped for SLCO1B1.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;830(1):143-50.