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Haruki Otsuka

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Shinya Yamada; Yasunobu Matsumoto; Yasuhiro Takashima; Haruki Otsuka
Mutation hot spots in the canine herpesvirus thymidine kinase gene.
Yasuhiro Takashima; Mikuru Tsukamoto; Haruko Ota; Yasunobu Matsumoto; Yoshihiro Hayashi; Haruki Otsuka
Immunization with pseudorabies virus harboring Fc domain of IgG makes a contribution to protection of mice from lethal challenge.
Sunao Hayashi; Yasuhiro Takashima; Haruki Otsuka
Pseudorabies virus propagated in rabbit kidney-derived RK13 cells is neutralized by natural IgM antibodies in normal swine serum which specifically lyse host cells.

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All Publications

2005: Shinya Yamada; Yasunobu Matsumoto; Yasuhiro Takashima; Haruki Otsuka
Mutation hot spots in the canine herpesvirus thymidine kinase gene.
Virus genes 2005;31(1):107-11.
2005: Yasuhiro Takashima; Mikuru Tsukamoto; Haruko Ota; Yasunobu Matsumoto; Yoshihiro Hayashi; Haruki Otsuka
Immunization with pseudorabies virus harboring Fc domain of IgG makes a contribution to protection of mice from lethal challenge.
Vaccine 2005;23(29):3775-82.
2005: Sunao Hayashi; Yasuhiro Takashima; Haruki Otsuka
Pseudorabies virus propagated in rabbit kidney-derived RK13 cells is neutralized by natural IgM antibodies in normal swine serum which specifically lyse host cells.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2005;67(3):229-34.
2004: Orkash Hushur; Yasuhiro Takashima; Yasunobu Matsumoto; Haruki Otsuka
Restriction of bovine herpesvirus 1 (BHV-1) growth in non-permissive cells beyond the expression of immediate early genes.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2004;66(4):453-5.
2004: Y Kaneko; Yasuhiro Takashima; X Xuaun; Ikuo Igarashi; Hideyuki Nagasawa; Takeshi Mikami; Haruki Otsuka
Natural IgM antibodies in sera from various animals but not the cat kill Toxoplasma gondii by activating the classical complement pathway.
Parasitology 2004;128(Pt 2):123-9.
2004: Sunao Hayashi; Seiji Ogawa; Yasuhiro Takashima; Haruki Otsuka
The neutralization of pseudorabies virus by anti-alpha-galactocyl natural antibody in normal serum.
Virus research 2004;99(1):1-7.
2003: Takahiro Okuno; Yasuyuki Goto; Yoshitsugu Matsumoto; Haruki Otsuka; Yasunobu Matsumoto
Applications of recombinant Leishmania amazonensis expressing egfp or the beta-galactosidase gene for drug screening and histopathological analysis.
Experimental animals / Japanese Association for Laboratory Animal Science 2003;52(2):109-18.
2003: Yasuhiro Takashima; Mohamed Mohamed Ahmed; Isao Kimata; Motohiro Iseki; Yoshikatsu Kodama; Noriko Nagane; Hideyuki Nagasawa; Yasunobu Matsumoto; Takeshi Mikami; Haruki Otsuka
Recombinant bovine herpesvirus-1 expressing p23 protein of Cryptosporidium parvum induces neutralizing antibodies in rabbits.
The Journal of parasitology 2003;89(2):276-82.
2002: Kazuo Nakamichi; Yasunobu Matsumoto; Haruki Otsuka
Bovine herpesvirus 1 U(S) ORF8 protein induces apoptosis in infected cells and facilitates virus egress.
Virology 2002;304(1):24-32.
2002: Takahiro Okuno; Makoto Takeuchi; Yoshitsugu Matsumoto; Haruki Otsuka; Yasunobu Matsumoto
Pretreatment of leishmania homologue of receptors for activated C kinase (LACK) promotes disease progression caused by Leishmania amazonensis.
Experimental animals / Japanese Association for Laboratory Animal Science 2002;51(4):335-41.
2002: Yasuhiro Takashima; Noriko Nagane; Orkash Hushur; Yasunobu Matsumoto; Haruki Otsuka
Bovine herpesvirus-1 (BHV-1) recombinant expressing pseudorabies virus (PrV) glycoproteins B and C induces type 1 immune response in BALB/c mice.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2002;64(7):589-96.
2002: Yoshifumi Nishikawa; Michiko Kimura; Mohamed Mohamed Ahmed; Levi Makala; Hideyuki Nagasawa; Takeshi Mikami; Haruki Otsuka
Canine herpesvirus ORF2 is a membrane protein modified by N-linked glycosylation.
Virus research 2002;87(1):1-9.
2002: Kohshi Maeda; Sunao Hayashi; Yoshikuni Tanioka; Yasunobu Matsumoto; Haruki Otsuka
Pseudorabies virus (PRV) is protected from complement attack by cellular factors and glycoprotein C (gC).
Virus research 2002;84(1-2):79-87.
2002: Kazuo Nakamichi; Yasunobu Matsumoto; Haruki Otsuka
Bovine herpesvirus 1 glycoprotein G is necessary for maintaining cell-to-cell junctional adherence among infected cells.
Virology 2002;294(1):22-30.
2002: Kazuo Nakamichi; Yasunobu Matsumoto; Yukinobu Tohya; Haruki Otsuka
Induction of apoptosis in rabbit kidney cell under high-level expression of bovine herpesvirus 1 U(s) ORF8 product.
Intervirology 2002;45(2):85-93.
2001: Kazuo Nakamichi; Yoshitsugu Matsumoto; Haruki Otsuka
Defective infection of bovine herpesvirus 1 in non-permissive murine cells.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2001;63(10):1139-42.
2001: Kazuo Nakamichi; D Kuroki; Yoshitsugu Matsumoto; Haruki Otsuka
Bovine herpesvirus 1 glycoprotein G is required for prevention of apoptosis and efficient viral growth in rabbit kidney cells.
Virology 2001;279(2):488-98.
2000: Yasuhiro Takashima; Yoshitsugu Matsumoto; Haruki Otsuka
Suppression of the proliferation of mouse splenocytes by pseudorabies virus.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2000;62(11):1227-30.
2000: Kazuo Nakamichi; K Ohara; Yoshitsugu Matsumoto; Haruki Otsuka
Attachment and penetration of canine herpesvirus 1 in non-permissive cells.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2000;62(9):965-70.
2000: Yasuo Ikeda; I Shibata; Mohamed Mohamed Ahmed; Yoshitsugu Matsumoto; Haruki Otsuka
Immunogenic properties of a bovine herpesvirus-1 (BHV-1) recombinant expressing major pseudorabies virus (PrV) glycoproteins in combination.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2000;62(8):849-59.
2000: Kazuo Nakamichi; K Ohara; D Kuroki; Haruki Otsuka
Bovine herpesvirus 1 glycoprotein G is required for viral growth by cell-to-cell infection.
Virus research 2000;68(2):175-81.
2000: Yasuhiro Takashima; Haruki Otsuka
[Pathogenesis of animal herpesviruses to human].
Nihon rinsho. Japanese journal of clinical medicine 2000;58(4):957-61.
2000: Kazuo Nakamichi; Haruki Otsuka
Attachment and penetration properties of bovine herpesvirus 1 recombinants expressing pseudorabies virus glycoproteins gC and gB.
Intervirology 2000;43(2):87-94.
1999: Yoshifumi Nishikawa; Mohamed Mohamed Ahmed; M Kimura; Haruki Otsuka
Characterization of pseudorabies virus glycoprotein B expressed by canine herpesvirus.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 1999;61(10):1113-7.
1999: Y Takasima; Mohamed Mohamed Ahmed; Y Matsumoto; M Onuma; Haruki Otsuka
Antibodies produced by mice immunized with recombinant vaccinia viruses expressing two different types of a major Theileria sergenti surface antigen (p32) react with the native surface antigen.
Veterinary parasitology 1999;84(1-2):65-73.
1999: T Murata; Yasuhiro Takashima; Mohamed Mohamed Ahmed; Haruki Otsuka
Growth behavior of bovine herpesvirus-1 in permissive and semi-permissive cells.
Virus research 1999;61(1):29-41.
1999: Yoshifumi Nishikawa; Mohamed Mohamed Ahmed; Haruki Otsuka
Biosynthesis and interaction of glycoproteins E and I of canine herpesvirus.
Virus research 1999;61(1):11-8.
1999: T Murata; Mohamed Mohamed Ahmed; Haruki Otsuka
Characterization of promoters integrated in the genome of bovine herpesvirus-1 (BHV-1).
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 1999;61(5):453-7.
1999: Yasuhiro Takashima; H Tamura; Mohamed Mohamed Ahmed; Haruki Otsuka
Identification of the US3 gene product of BHV-1 as a protein kinase and characterization of BHV-1 mutants of the US3 gene.
Virus research 1999;59(1):23-34.
1998: Yoshifumi Nishikawa; Mohamed Mohamed Ahmed; Haruki Otsuka
Identification and characterization of the glycoprotein E and I genes of canine herpesvirus.
Virus research 1998;56(1):77-92.
1998: Mohamed Mohamed Ahmed; Kotaro Tuchiya; I Sato; Yoshifumi Nishikawa; Y Onoderaz; Yasuhiro Takashima; Akira Yamamoto; A Katsumata; Akira Iwata; Susumu Ueda; Takeshi Mikami; Haruki Otsuka
Biological and immunogenic properties of rabies virus glycoprotein expressed by canine herpesvirus vector.
Vaccine 1998;16(9-10):969-76.
1998: Mohamed Mohamed Ahmed; Yoshifumi Nishikawa; Yasuhiro Takashima; Kotaro Tuchiya; Susumu Ueda; N Yokoyama; Kohshi Maeda; Takeshi Mikami; Haruki Otsuka
Construction of canine herpesvirus vector expressing foreign genes using a lacZ-TK gene cassette as a double selectional marker.
Virus genes 1998;17(1):25-32.
1996: Mohamed Mohamed Ahmed; Kohshi Maeda; Takeshi Mikami; Haruki Otsuka
Characterization of canine herpesvirus glycoprotein C expressed by a recombinant baculovirus in insect cells.
Virus research 1996;46(1-2):57-64.
1996: Haruki Otsuka; Mohamed Mohamed Ahmed; I Shibata; M Mori
Protective immunity of bovine herpesvirus-1 (BHV-1) recombinants which express pseudorabies virus (PRV) glycoproteins gB, gC, gD and gE.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 1996;58(9):819-24.
1996: Mohamed Mohamed Ahmed; Kohshi Maeda; Yukinobu Tohya; Takeshi Mikami; Haruki Otsuka
Identification and nucleotide sequence of the thymidine kinase gene of canine herpesvirus.
Virus genes 1996;12(2):185-8.
1996: Haruki Otsuka; Mohamed Mohamed Ahmed
Construction of bovine herpesvirus-1 (BHV-1) recombinants which express pseudorabies virus (PRV) glycoproteins gB, gC, gD, and gE.
Archives of virology 1996;141(1):57-71.
1992: S Kamata; A Ohkawa; O Ito; N Kakiichi; K Komine; T Matsunaga; M Hayashi; M Sugiyama; Haruki Otsuka; S Ura
Preliminary experiment for detection of penicillinase by enzyme-linked immunosorbent assay and western blotting technique.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 1992;54(2):395-7.