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Uwe Otten

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Pia März-Weiss; Uwe Otten; Suat Ozbek; Johannes Haybaeck; Dieter Kunz; Caroline Berkemeier; Daniel Bimmler; Beatrice Dimitriades-Schmutz; Rolf Graf
Expression of pancreatitis-associated protein after traumatic brain injury: a mechanism potentially contributing to neuroprotection in human brain.
Dieter Kunz; Gaby Walker; Marc Bedoucha; Ulrich Certa; Pia März-Weiss; Beatrice Dimitriades-Schmutz; Uwe Otten
Expression profiling and Ingenuity biological function analyses of interleukin-6- versus nerve growth factor-stimulated PC12 cells.
Sabine Schnydrig; Lukas Korner; Svenja Landweer; Beat Ernst; Gaby Walker; Uwe Otten; Dieter Kunz
Peripheral lipopolysaccharide administration transiently affects expression of brain-derived neurotrophic factor, corticotropin and proopiomelanocortin in mouse brain.

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All Publications

2011: Pia März-Weiss; Uwe Otten; Suat Ozbek; Johannes Haybaeck; Dieter Kunz; Caroline Berkemeier; Daniel Bimmler; Beatrice Dimitriades-Schmutz; Rolf Graf
Expression of pancreatitis-associated protein after traumatic brain injury: a mechanism potentially contributing to neuroprotection in human brain.
Cellular and molecular neurobiology 2011;31(8):1141-9.
2009: Dieter Kunz; Gaby Walker; Marc Bedoucha; Ulrich Certa; Pia März-Weiss; Beatrice Dimitriades-Schmutz; Uwe Otten
Expression profiling and Ingenuity biological function analyses of interleukin-6- versus nerve growth factor-stimulated PC12 cells.
BMC genomics 2009;10():90.
2007: Sabine Schnydrig; Lukas Korner; Svenja Landweer; Beat Ernst; Gaby Walker; Uwe Otten; Dieter Kunz
Peripheral lipopolysaccharide administration transiently affects expression of brain-derived neurotrophic factor, corticotropin and proopiomelanocortin in mouse brain.
Neuroscience letters 2007;429(1):69-73.
2007: Pia März; Uwe Otten; André R Miserez
Statins induce differentiation and cell death in neurons and astroglia.
Glia 2007;55(1):1-12.
2006: Pia März; Jörg Stetefeld; Kerstin Bendfeldt; Cordula Nitsch; Jochen Reinstein; Robert L Shoeman; Beatrice Dimitriades-Schmutz; Martine Schwager; Dominic Leiser; Sabire Ozcan; Uwe Otten; Suat Ozbek
Ataxin-10 interacts with O-linked beta-N-acetylglucosamine transferase in the brain.
The Journal of biological chemistry 2006;281(29):20263-70.
2006: Florence Vollenweider; Kerstin Bendfeldt; Walter Maetzler; Uwe Otten; Cordula Nitsch
GABA(B) receptor expression and cellular localization in gerbil hippocampus after transient global ischemia.
Neuroscience letters 2006;395(2):118-23.
2004: Pia März; Alphonse Probst; Sigrid Lang; Martine Schwager; Stefan Rose-John; Uwe Otten; Suat Ozbek
Ataxin-10, the spinocerebellar ataxia type 10 neurodegenerative disorder protein, is essential for survival of cerebellar neurons.
The Journal of biological chemistry 2004;279(34):35542-50.
2004: Thomas Roskoden; Uwe Otten; Herbert Schwegler
Early postnatal corticosterone administration regulates neurotrophins and their receptors in septum and hippocampus of the rat.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2004;154(2):183-91.
2003: Florence Vollenweider; Martina Herrmann; Uwe Otten; Cordula Nitsch
Interleukin-6 receptor expression and localization after transient global ischemia in gerbil hippocampus.
Neuroscience letters 2003;341(1):49-52.
2003: Klaus Heese; Karl-Friedrich Beck; Meik Helmut Behrens; Katharina Plüss; Wolfgang Fierlbeck; Andrea Huwiler; Heiko Muhl; Helmut Geiger; Uwe Otten; Josef Pfeilschifter
Effects of high glucose on cytokine-induced nerve growth factor (NGF) expression in rat renal mesangial cells.
Biochemical pharmacology 2003;65(2):293-301.
2003: Gianfranco Olivieri; Uwe Otten; Fides Meier; G Baysang; Beatrice Dimitriades-Schmutz; Franz Müller-Spahn; Egemen Savaskan
Beta-amyloid modulates tyrosine kinase B receptor expression in SHSY5Y neuroblastoma cells: influence of the antioxidant melatonin.
Neuroscience 2003;120(3):659-65.
2002: Yi Sun; Pia März; Uwe Otten; Jiguang Ge; Stefan Rose-John
The effect of gp130 stimulation on glutamate-induced excitotoxicity in primary hippocampal neurons.
Biochemical and biophysical research communications 2002;295(2):532-9.
2002: Pia März; Suat Ozbek; Martina Fischer; Nicole Voltz; Uwe Otten; Stefan Rose-John
Differential response of neuronal cells to a fusion protein of ciliary neurotrophic factor/soluble CNTF-receptor and leukemia inhibitory factor.
European journal of biochemistry / FEBS 2002;269(12):3023-31.
2002: Gianfranco Olivieri; Uwe Otten; Fides Meier; G Baysang; Beatrice Dimitriades-Schmutz; Franz Müller-Spahn; Egemen Savaskan
Oxidative stress modulates tyrosine kinase receptor A and p75 receptor (low-affinity nerve growth factor receptor) expression in SHSY5Y neuroblastoma cells.
Neurology & clinical neurophysiology : NCN 2002;2002(2):2-10.
2001: G Walker; Josef Pfeilschifter; Uwe Otten; D Kunz
Proteolytic cleavage of inducible nitric oxide synthase (iNOS) by calpain I.
Biochimica et biophysica acta 2001;1568(3):216-24.
2001: Uwe Otten; Pia März; Klaus Heese; Christoph Hock; D Kunz; Stefan Rose-John
Signals regulating neurotrophin expression in glial cells.
Progress in brain research 2001;132():545-54.
2000: Claudia Grothe; Klaus Heese; C Meisinger; Konstantin Wewetzer; D Kunz; Peter A Cattini; Uwe Otten
Expression of interleukin-6 and its receptor in the sciatic nerve and cultured Schwann cells: relation to 18-kD fibroblast growth factor-2.
Brain research 2000;885(2):172-81.
2000: Christoph Hock; Klaus Heese; Franz Müller-Spahn; P Huber; Walter Riesen; Roger M Nitsch; Uwe Otten
Increased cerebrospinal fluid levels of neurotrophin 3 (NT-3) in elderly patients with major depression.
Molecular psychiatry 2000;5(5):510-3.
2000: Christoph Hock; Klaus Heese; CH Hulette; C Rosenberg; Uwe Otten
Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas.
Archives of neurology 2000;57(6):846-51.
2000: Christoph Hock; Klaus Heese; Franz Müller-Spahn; P Huber; Walter Riesen; Roger M Nitsch; Uwe Otten
Increased CSF levels of nerve growth factor in patients with Alzheimer's disease.
Neurology 2000;54(10):2009-11.
2000: Klaus Heese; Uwe Otten; P Mathivet; M Raiteri; Christian Marescaux; R Bernasconi
GABA(B) receptor antagonists elevate both mRNA and protein levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) but not neurotrophin-3 (NT-3) in brain and spinal cord of rats.
Neuropharmacology 2000;39(3):449-62.
2000: Uwe Otten; Pia März; Klaus Heese; Christoph Hock; D Kunz; Stefan Rose-John
Cytokines and neurotrophins interact in normal and diseased states.
Annals of the New York Academy of Sciences 2000;917():322-30.
2000: Egemen Savaskan; Franz Müller-Spahn; Gianfranco Olivieri; S Bruttel; Uwe Otten; C Rosenberg; CH Hulette; Christoph Hock
Alterations in trk A, trk B and trk C receptor immunoreactivities in parietal cortex and cerebellum in Alzheimer's disease.
European neurology 2000;44(3):172-80.
2000: Christoph Hock; Klaus Heese; Gianfranco Olivieri; CH Hulette; C Rosenberg; Roger M Nitsch; Uwe Otten
Alterations in neurotrophins and neurotrophin receptors in Alzheimer's disease.
Journal of neural transmission. Supplementum 2000;59():171-4.
1999: Pia März; Uwe Otten; Stefan Rose-John
Neural activities of IL-6-type cytokines often depend on soluble cytokine receptors.
The European journal of neuroscience 1999;11(9):2995-3004.
1999: Thomas Roskoden; Klaus Heese; Uwe Otten; Herbert Schwegler
Modulation of mRNA expression of the neurotrophins of the nerve-growth-factor family and their receptors in the septum and hippocampus of rats after transient postnatal thyroxine treatment. II. Effects on p75 and trk receptor expression.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1999;127(3):307-13.
1999: Pia März; Klaus Heese; Beatrice Dimitriades-Schmutz; Stefan Rose-John; Uwe Otten
Role of interleukin-6 and soluble IL-6 receptor in region-specific induction of astrocytic differentiation and neurotrophin expression.
Glia 1999;26(3):191-200.
1999: M Thier; Pia März; Uwe Otten; Joachim Weis; Stefan Rose-John
Interleukin-6 (IL-6) and its soluble receptor support survival of sensory neurons.
Journal of neuroscience research 1999;55(4):411-22.
1998: Klaus Heese; B L Fiebich; J Bauer; Uwe Otten
NF-kappaB modulates lipopolysaccharide-induced microglial nerve growth factor expression.
Glia 1998;22(4):401-7.
1998: Pia März; JG Cheng; RA Gadient; Paul H Patterson; T Stoyan; Uwe Otten; Stefan Rose-John
Sympathetic neurons can produce and respond to interleukin 6.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):3251-6.
1998: Hans Gerd Lüesse; Thomas Roskoden; Rüdiger Linke; Uwe Otten; Klaus Heese; Herbert Schwegler
Modulation of mRNA expression of the neurotrophins of the nerve growth factor family and their receptors in the septum and hippocampus of rats after transient postnatal thyroxine treatment. I. Expression of nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin 4 mRNA.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1998;119(1):1-8.
1998: Klaus Heese; Christoph Hock; Uwe Otten
Inflammatory signals induce neurotrophin expression in human microglial cells.
Journal of neurochemistry 1998;70(2):699-707.
1998: Christoph Hock; Klaus Heese; Franz Müller-Spahn; CH Hulette; C Rosenberg; Uwe Otten
Decreased trkA neurotrophin receptor expression in the parietal cortex of patients with Alzheimer's disease.
Neuroscience letters 1998;241(2-3):151-4.
1997: Pia März; Klaus Heese; Christoph Hock; S Golombowski; Franz Müller-Spahn; Stefan Rose-John; Uwe Otten
Interleukin-6 (IL-6) and soluble forms of IL-6 receptors are not altered in cerebrospinal fluid of Alzheimer's disease patients.
Neuroscience letters 1997;239(1):29-32.
1997: E Hösli; Uwe Otten; L Hösli
Expression of GABA(A) receptors by reactive astrocytes in explant and primary cultures of rat CNS.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1997;15(8):949-60.
1997: Pia März; Thomas Herget; E Lang; Uwe Otten; Stefan Rose-John
Activation of gp130 by IL-6/soluble IL-6 receptor induces neuronal differentiation.
The European journal of neuroscience 1997;9(12):2765-73.
1997: Klaus Heese; B L Fiebich; J Bauer; Uwe Otten
Nerve growth factor (NGF) expression in rat microglia is induced by adenosine A2a-receptors.
Neuroscience letters 1997;231(2):83-6.
1997: RA Gadient; Uwe Otten
Interleukin-6 (IL-6)--a molecule with both beneficial and destructive potentials.
Progress in neurobiology 1997;52(5):379-90.
1996: RA Gadient; Uwe Otten
Postnatal expression of interleukin-6 (IL-6) and IL-6 receptor (IL-6R) mRNAs in rat sympathetic and sensory ganglia.
Brain research 1996;724(1):41-6.
1996: Pia März; RA Gadient; Uwe Otten
Expression of interleukin-6 receptor (IL-6R) and gp130 mRNA in PC12 cells and sympathetic neurons: modulation by tumor necrosis factor alpha (TNF-alpha).
Brain research 1996;706(1):71-9.
1995: K M Plüss; Josef Pfeilschifter; Heiko Muhl; Andrea Huwiler; C Boeckh; Uwe Otten
Modulatory role of platelet-derived growth factor on cytokine-induced nerve growth factor synthesis in rat glomerular mesangial cells.
The Biochemical journal 1995;312 ( Pt 3)():707-11.
1995: B C Figueiredo; K Plüss; M Skup; Uwe Otten; A Claudio Cuello
Acidic FGF induces NGF and its mRNA in the injured neocortex of adult animals.
Brain research. Molecular brain research 1995;33(1):1-6.
1995: RA Gadient; Uwe Otten
Interleukin-6 and interleukin-6 receptor mRNA expression in rat central nervous system.
Annals of the New York Academy of Sciences 1995;762():403-6.
1995: RA Gadient; A Lachmund; K Unsicker; Uwe Otten
Expression of interleukin-6 (IL-6) and IL-6 receptor mRNAs in rat adrenal medulla.
Neuroscience letters 1995;194(1-2):17-20.
1995: J L Scully; Uwe Otten
Neurotrophin expression modulated by glucocorticoids and oestrogen in immortalized hippocampal neurons.
Brain research. Molecular brain research 1995;31(1-2):158-64.
1995: Uwe Otten; RA Gadient
Neurotrophins and cytokines--intermediaries between the immune and nervous systems.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1995;13(3-4):147-51.
1995: J L Scully; Uwe Otten
Glucocorticoids, neurotrophins and neurodegeneration.
The Journal of steroid biochemistry and molecular biology 1995;52(5):391-401.
1995: J L Scully; Uwe Otten
NGF: not just for neurons.
Cell biology international 1995;19(5):459-69.
1995: T Janet; G Lüdecke; Uwe Otten; Klaus Unsicker
Heterogeneity of human neuroblastoma cell lines in their proliferative responses to basic FGF, NGF, and EGF: correlation with expression of growth factors and growth factor receptors.
Journal of neuroscience research 1995;40(6):707-15.
1994: RA Gadient; Uwe Otten
Identification of interleukin-6 (IL-6)-expressing neurons in the cerebellum and hippocampus of normal adult rats.
Neuroscience letters 1994;182(2):243-6.
1994: A Straube; R Bender; Uwe Otten; Michael Frotscher
Expression of the cholecystokinin gene in rat hippocampal interneurons is independent of extrinsic input.
Neuroscience letters 1994;172(1-2):143-6.
1994: P B Ehrhard; Peter Erb; U Graumann; B Schmutz; Uwe Otten
Expression of functional trk tyrosine kinase receptors after T cell activation.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(6):2705-9.
1994: S Strauss; Uwe Otten; B Joggerst; K Plüss; Benedikt Volk
Increased levels of nerve growth factor (NGF) protein and mRNA and reactive gliosis following kainic acid injection into the rat striatum.
Neuroscience letters 1994;168(1-2):193-6.
1994: RA Gadient; Uwe Otten
Expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat brain during postnatal development.
Brain research 1994;637(1-2):10-4.
1994: P B Ehrhard; Uwe Otten
Postnatal ontogeny of the neurotrophin receptors trk and trkB mRNA in rat sensory and sympathetic ganglia.
Neuroscience letters 1994;166(2):207-10.
1994: Uwe Otten; J L Scully; P B Ehrhard; RA Gadient
Neurotrophins: signals between the nervous and immune systems.
Progress in brain research 1994;103():293-305.
1993: P B Ehrhard; Peter Erb; U Graumann; Uwe Otten
Expression of nerve growth factor and nerve growth factor receptor tyrosine kinase Trk in activated CD4-positive T-cell clones.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):10984-8.
1993: P B Ehrhard; U Ganter; B Schmutz; J Bauer; Uwe Otten
Expression of low-affinity NGF receptor and trkB mRNA in human SH-SY5Y neuroblastoma cells.
FEBS letters 1993;330(3):287-92.
1993: S Bahn; U Ganter; J Bauer; Uwe Otten; Benedikt Volk
Influence of phenytoin on cytoskeletal organization and cell viability of immortalized mouse hippocampal neurons.
Brain research 1993;615(1):160-9.
1993: P B Ehrhard; U Ganter; Anna K Stalder; J Bauer; Uwe Otten
Expression of functional trk protooncogene in human monocytes.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(12):5423-7.
1993: Eckart Förster; Uwe Otten; Michael Frotscher
Developmental neurotrophin expression in slice cultures of rat hippocampus.
Neuroscience letters 1993;155(2):216-9.
1993: J L Scully; Uwe Otten
Glucocorticoid modulation of neurotrophin expression in immortalized mouse hippocampal neurons.
Neuroscience letters 1993;155(1):11-4.
1993: RA Gadient; Uwe Otten
Differential expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat hypothalamus.
Neuroscience letters 1993;153(1):13-16.
1993: B C Figueiredo; Uwe Otten; S Strauss; B Volk; Dusica Maysinger
Effects of perinatal hypo- and hyperthyroidism on the levels of nerve growth factor and its low-affinity receptor in cerebellum.
Brain research. Developmental brain research 1993;72(2):237-44.
1993: D G Herrera; Dusica Maysinger; RA Gadient; C Boeckh; Uwe Otten; A Claudio Cuello
Spreading depression induces c-fos-like immunoreactivity and NGF mRNA in the rat cerebral cortex.
Brain research 1993;602(1):99-103.
1991: P Steiner; Josef Pfeilschifter; C Boeckh; Heinfried Radeke; Uwe Otten
Interleukin-1 beta and tumor necrosis factor-alpha synergistically stimulate nerve growth factor synthesis in rat mesangial cells.
The American journal of physiology 1991;261(5 Pt 2):F792-8.
1990: RA Gadient; K C Cron; Uwe Otten
Interleukin-1 beta and tumor necrosis factor-alpha synergistically stimulate nerve growth factor (NGF) release from cultured rat astrocytes.
Neuroscience letters 1990;117(3):335-40.
1990: P Ehrhard; F Gudat; Uwe Otten
Measurement of human nerve growth factor binding sites in brain and in peripheral tissues by a specific immunoprecipitation assay.
Naunyn-Schmiedeberg's archives of pharmacology 1990;342(3):251-7.
1989: Uwe Otten; P Ehrhard; R Peck
Nerve growth factor induces growth and differentiation of human B lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):10059-63.
1988: R Westermann; M Hardung; Dieter K Meyer; P Ehrhard; Uwe Otten; Klaus Unsicker
Neuronotrophic factors released by C6 glioma cells.
Journal of neurochemistry 1988;50(6):1747-58.
1987: D M White; P Ehrhard; M Hardung; Dieter K Meyer; M Zimmermann; Uwe Otten
Substance P modulates the release of locally synthesized nerve growth factor from rat saphenous nerve neuroma.
Naunyn-Schmiedeberg's archives of pharmacology 1987;336(5):587-90.
1976: Uwe Otten; H Thoenen
Role of membrane depolarization in transsynaptic induction of tyrosine hydroxylase in organ cultures of sympathetic ganglia.
Neuroscience letters 1976;2(2):93-6.