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Gottfried Otting

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Phenomena

Magnetic Resonance Spectroscopy

Procedures

Biomolecular Nuclear Magnetic Resonance

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequence

Chemicals & Drugs

Living Beings

Escherichia coli

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Publications

TOP 3
Bodenreider Christophe; Beer David; Keller Thomas H; Sonntag Sebastian; Wen Daying; Yap Lijian; Yau Yin Hoe; Shochat Susana Geifman; Huang Danzhi; Zhou Ting; Caflisch Amedeo; Su Xun-Cheng; Ozawa Kiyoshi; Otting Gottfried; Vasudevan Subhash G; Lescar Julien; Lim Siew Pheng
A fluorescence quenching assay to discriminate between specific and nonspecific inhibitors of dengue virus protease.
Su Xun-Cheng; Liang Haobo; Loscha Karin V; Otting Gottfried
[Ln(DPA)(3)](3-) is a convenient paramagnetic shift reagent for protein NMR studies.
Su Xun-Cheng; Ozawa Kiyoshi; Yagi Hiromasa; Lim Siew P; Wen Daying; Ekonomiuk Dariusz; Huang Danzhi; Keller Thomas H; Sonntag Sebastian; Caflisch Amedeo; Vasudevan Subhash G; Otting Gottfried
NMR study of complexes between low molecular mass inhibitors and the West Nile virus NS2B-NS3 protease.

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All Publications

2009: Bodenreider Christophe; Beer David; Keller Thomas H; Sonntag Sebastian; Wen Daying; Yap Lijian; Yau Yin Hoe; Shochat Susana Geifman; Huang Danzhi; Zhou Ting; Caflisch Amedeo; Su Xun-Cheng; Ozawa Kiyoshi; Otting Gottfried; Vasudevan Subhash G; Lescar Julien; Lim Siew Pheng
A fluorescence quenching assay to discriminate between specific and nonspecific inhibitors of dengue virus protease.
Analytical biochemistry 2009;395(2):195-204.
2009: Su Xun-Cheng; Liang Haobo; Loscha Karin V; Otting Gottfried
[Ln(DPA)(3)](3-) is a convenient paramagnetic shift reagent for protein NMR studies.
Journal of the American Chemical Society 2009;131(30):10352-3.
2009: Su Xun-Cheng; Ozawa Kiyoshi; Yagi Hiromasa; Lim Siew P; Wen Daying; Ekonomiuk Dariusz; Huang Danzhi; Keller Thomas H; Sonntag Sebastian; Caflisch Amedeo; Vasudevan Subhash G; Otting Gottfried
NMR study of complexes between low molecular mass inhibitors and the West Nile virus NS2B-NS3 protease.
The FEBS journal 2009;276(15):4244-55.
2009: Ekonomiuk Dariusz; Su Xun-Cheng; Ozawa Kiyoshi; Bodenreider Christophe; Lim Siew Pheng; Otting Gottfried; Huang Danzhi; Caflisch Amedeo
Flaviviral protease inhibitors identified by fragment-based library docking into a structure generated by molecular dynamics.
Journal of medicinal chemistry 2009;52(15):4860-8.
2009: Jia Xinying; Ozawa Kiyoshi; Loscha Karin; Otting Gottfried
Glutarate and N-acetyl-L-glutamate buffers for cell-free synthesis of selectively 15N-labelled proteins.
Journal of biomolecular NMR 2009;44(2):59-67.
2009: Loscha Karin V; Jaudzems Kristaps; Ioannou Charikleia; Su Xun-Cheng; Hill Flynn R; Otting Gottfried; Dixon Nicholas E; Liepinsh Edvards
A novel zinc-binding fold in the helicase interaction domain of the Bacillus subtilis DnaI helicase loader.
Nucleic acids research 2009;37(7):2395-404.
2009: Ekonomiuk Dariusz; Su Xun-Cheng; Ozawa Kiyoshi; Bodenreider Christophe; Lim Siew Pheng; Yin Zheng; Keller Thomas H; Beer David; Patel Viral; Otting Gottfried; Caflisch Amedeo; Huang Danzhi
Discovery of a non-peptidic inhibitor of west nile virus NS3 protease by high-throughput docking.
PLoS neglected tropical diseases 2009;3(1):e356.
2008: Otting Gottfried
Prospects for lanthanides in structural biology by NMR.
Journal of biomolecular NMR 2008;42(1):1-9.
2008: Ozawa Kiyoshi; Jergic Slobodan; Park Ah Young; Dixon Nicholas E; Otting Gottfried
The proofreading exonuclease subunit epsilon of Escherichia coli DNA polymerase III is tethered to the polymerase subunit alpha via a flexible linker.
Nucleic acids research 2008;36(15):5074-82.
2008: Su Xun-Cheng; Man Bradley; Beeren Sophie; Liang Haobo; Simonsen Shane; Schmitz Christophe; Huber Thomas; Messerle Barbara A; Otting Gottfried
A dipicolinic acid tag for rigid lanthanide tagging of proteins and paramagnetic NMR spectroscopy.
Journal of the American Chemical Society 2008;130(32):10486-7.
2008: Schmitz Christophe; Stanton-Cook Mitchell J; Su Xun-Cheng; Otting Gottfried; Huber Thomas
Numbat: an interactive software tool for fitting Deltachi-tensors to molecular coordinates using pseudocontact shifts.
Journal of biomolecular NMR 2008;41(3):179-89.
2008: Su Xun-Cheng; McAndrew Kerry; Huber Thomas; Otting Gottfried
Lanthanide-binding peptides for NMR measurements of residual dipolar couplings and paramagnetic effects from multiple angles.
Journal of the American Chemical Society 2008;130(5):1681-7.
2008: Dabb Serin L; Messerle Barbara A; Otting Gottfried; Wagler Jörg; Willis Anthony
Ruthenium complexes of substituted hydrazine: new solution- and solid-state binding modes.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(32):10058-65.
2008: Apponyi Margit A; Ozawa Kiyoshi; Dixon Nicholas E; Otting Gottfried
Cell-free protein synthesis for analysis by NMR spectroscopy.
Methods in molecular biology (Clifton, N.J.) 2008;426():257-68.
2007: John Michael; Schmitz Christophe; Park Ah Young; Dixon Nicholas E; Huber Thomas; Otting Gottfried
Sequence-specific and stereospecific assignment of methyl groups using paramagnetic lanthanides.
Journal of the American Chemical Society 2007;129(44):13749-57.
2007: John Michael; Otting Gottfried
Strategies for measurements of pseudocontact shifts in protein NMR spectroscopy.
Chemphyschem : a European journal of chemical physics and physical chemistry 2007;8(16):2309-13.
2007: Watt Stephen J; Sheil Margaret M; Beck Jennifer L; Prosselkov Pavel; Otting Gottfried; Dixon Nicholas E
Effect of protein stabilization on charge state distribution in positive- and negative-ion electrospray ionization mass spectra.
Journal of the American Society for Mass Spectrometry 2007;18(9):1605-11.
2007: Su Xun-Cheng; Jergic Slobodan; Ozawa Kiyoshi; Burns Nicolas Dale; Dixon Nicholas E; Otting Gottfried
Measurement of dissociation constants of high-molecular weight protein-protein complexes by transferred 15N-relaxation.
Journal of biomolecular NMR 2007;38(1):65-72.
2007: Pintacuda Guido; John Michael; Su Xun-Cheng; Otting Gottfried
NMR structure determination of protein-ligand complexes by lanthanide labeling.
Accounts of chemical research 2007;40(3):206-12.
2007: John Michael; Park Ah Young; Dixon Nicholas E; Otting Gottfried
NMR detection of protein 15N spins near paramagnetic lanthanide ions.
Journal of the American Chemical Society 2007;129(3):462-3.
2007: John Michael; Headlam Madeleine J; Dixon Nicholas E; Otting Gottfried
Assignment of paramagnetic (15)N-HSQC spectra by heteronuclear exchange spectroscopy.
Journal of biomolecular NMR 2007;37(1):43-51.
2007: Su Xun-Cheng; Jergic Slobodan; Keniry Max A; Dixon Nicholas E; Otting Gottfried
Solution structure of Domains IVa and V of the tau subunit of Escherichia coli DNA polymerase III and interaction with the alpha subunit.
Nucleic acids research 2007;35(9):2825-32.
2007: Wu Peter S C; Ozawa Kiyoshi; Lim Siew P; Vasudevan Subhash G; Dixon Nicholas E; Otting Gottfried
Cell-free transcription/translation from PCR-amplified DNA for high-throughput NMR studies.
Angewandte Chemie (International ed. in English) 2007;46(18):3356-8.
2007: Jergic Slobodan; Ozawa Kiyoshi; Williams Neal K; Su Xun-Cheng; Scott Daniel D; Hamdan Samir M; Crowther Jeffrey A; Otting Gottfried; Dixon Nicholas E
The unstructured C-terminus of the tau subunit of Escherichia coli DNA polymerase III holoenzyme is the site of interaction with the alpha subunit.
Nucleic acids research 2007;35(9):2813-24.
2006: Su Xun-Cheng; Schaeffer Patrick M; Loscha Karin V; Gan Pamela H P; Dixon Nicholas E; Otting Gottfried
Monomeric solution structure of the helicase-binding domain of Escherichia coli DnaG primase.
The FEBS journal 2006;273(21):4997-5009.
2006: John Michael; Pintacuda Guido; Park Ah Young; Dixon Nicholas E; Otting Gottfried
Structure determination of protein-ligand complexes by transferred paramagnetic shifts.
Journal of the American Chemical Society 2006;128(39):12910-6.
2006: Su Xun-Cheng; Huber Thomas; Dixon Nicholas E; Otting Gottfried
Site-specific labelling of proteins with a rigid lanthanide-binding tag.
Chembiochem : a European journal of chemical biology 2006;7(10):1599-604.
2006: Ozawa Kiyoshi; Wu Peter S C; Dixon Nicholas E; Otting Gottfried
N-Labelled proteins by cell-free protein synthesis. Strategies for high-throughput NMR studies of proteins and protein-ligand complexes.
The FEBS journal 2006;273(18):4154-9.
2006: Schmitz Christophe; John Michael; Park Ah Young; Dixon Nicholas E; Otting Gottfried; Pintacuda Guido; Huber Thomas
Efficient chi-tensor determination and NH assignment of paramagnetic proteins.
Journal of biomolecular NMR 2006;35(2):79-87.
2006: Keniry Max A; Park Ah Young; Owen Elisabeth A; Hamdan Samir M; Pintacuda Guido; Otting Gottfried; Dixon Nicholas E
Structure of the theta subunit of Escherichia coli DNA polymerase III in complex with the epsilon subunit.
Journal of bacteriology 2006;188(12):4464-73.
2006: Liepinsh Edvards; Nagy Alinda; Trexler Mária; Patthy László; Otting Gottfried
Second Kunitz-type protease inhibitor domain of the human WFIKKN1 protein.
Journal of biomolecular NMR 2006;35(1):73-8.
2006: Pintacuda Guido; Park Ah Young; Keniry Max A; Dixon Nicholas E; Otting Gottfried
Lanthanide labeling offers fast NMR approach to 3D structure determinations of protein-protein complexes.
Journal of the American Chemical Society 2006;128(11):3696-702.
2006: Liepinsh Edvards; Bányai László; Patthy László; Otting Gottfried
NMR structure of the WIF domain of the human Wnt-inhibitory factor-1.
Journal of molecular biology 2006;357(3):942-50.
2006: Wu Peter S C; Ozawa Kiyoshi; Jergic Slobodan; Su Xun-Cheng; Dixon Nicholas E; Otting Gottfried
Amino-acid type identification in 15N-HSQC spectra by combinatorial selective 15N-labelling.
Journal of biomolecular NMR 2006;34(1):13-21.
2005: John Michael; Park Ah Young; Pintacuda Guido; Dixon Nicholas E; Otting Gottfried
Weak alignment of paramagnetic proteins warrants correction for residual CSA effects in measurements of pseudocontact shifts.
Journal of the American Chemical Society 2005;127(49):17190-1.
2005: Ozawa Kiyoshi; Dixon Nicholas E; Otting Gottfried
Cell-free synthesis of 15N-labeled proteins for NMR studies.
IUBMB life 2005;57(9):615-22.
2005: Hastings Adam F; Otting Gottfried; Folmer Rutger H A; Duggin Iain G; Wake R Gerry; Wilce Matthew C J; Wilce Jacqueline A
Interaction of the replication terminator protein of Bacillus subtilis with DNA probed by NMR spectroscopy.
Biochemical and biophysical research communications 2005;335(2):361-6.
2005: Wu Peter S C; Otting Gottfried
Rapid pulse length determination in high-resolution NMR.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2005;176(1):115-9.
2005: Wu Peter S C; Otting Gottfried
SWET for secure water suppression on probes with high quality factor.
Journal of biomolecular NMR 2005;32(3):243-50.
2005: Ozawa Kiyoshi; Jergic Slobodan; Crowther Jeffrey A; Thompson Phillip R; Wijffels Gene; Otting Gottfried; Dixon Nicholas A
Cell-free protein synthesis in an autoinduction system for NMR studies of protein-protein interactions.
Journal of biomolecular NMR 2005;32(3):235-41.
2005: Ozawa Kiyoshi; Headlam Madeleine J; Mouradov Dmitri; Watt Stephen J; Beck Jennifer L; Rodgers Kenneth J; Dean Roger T; Huber Thomas; Otting Gottfried; Dixon Nicholas E
Translational incorporation of L-3,4-dihydroxyphenylalanine into proteins.
The FEBS journal 2005;272(12):3162-71.
2005: Robinson Andrew; Wu Peter S-C; Harrop Stephen J; Schaeffer Patrick M; Dosztányi Zsuzsanna; Gillings Michael R; Holmes Andrew J; Nevalainen K M Helena; Stokes H W; Otting Gottfried; Dixon Nicholas E; Curmi Paul M G; Mabbutt Bridget C
Integron-associated mobile gene cassettes code for folded proteins: the structure of Bal32a, a new member of the adaptable alpha+beta barrel family.
Journal of molecular biology 2005;346(5):1229-41.
2005: Williams Neal K; Liepinsh Edvards; Watt Stephen J; Prosselkov Pavel; Matthews Jacqueline M; Attard Phil; Beck Jennifer L; Dixon Nicholas E; Otting Gottfried
Stabilization of native protein fold by intein-mediated covalent cyclization.
Journal of molecular biology 2005;346(4):1095-108.
2005: Oakley Aaron J; Loscha Karin V; Schaeffer Patrick M; Liepinsh Edvards; Pintacuda Guido; Wilce Matthew C J; Otting Gottfried; Dixon Nicholas E
Crystal and solution structures of the helicase-binding domain of Escherichia coli primase.
The Journal of biological chemistry 2005;280(12):11495-504.
2005: Moriya Mie; Taniguchi Shunichiro; Wu Peter; Liepinsh Edvards; Otting Gottfried; Sagara Junji
Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC.
Biochemistry 2005;44(2):575-83.
2004: Hoshino Masaru; Otting Gottfried
Sensitivity-enhanced double-TROSY experiment for simultaneous measurement of one-bond 15N-1H, 15N-13C' and two-bond 1H-13C' couplings.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2004;171(2):270-6.
2004: Pintacuda Guido; Kaikkonen Andrei; Otting Gottfried
Modulation of the distance dependence of paramagnetic relaxation enhancements by CSA x DSA cross-correlation.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2004;171(2):233-43.
2004: Liepinsh Edvards; Rakonjac Marija; Boissonneault Vincent; Provost Patrick; Samuelsson Bengt; Rådmark Olof; Otting Gottfried
NMR structure of human coactosin-like protein.
Journal of biomolecular NMR 2004;30(3):353-6.
2004: Ozawa Kiyoshi; Headlam Madeleine J; Schaeffer Patrick M; Henderson Blair R; Dixon Nicholas E; Otting Gottfried
Optimization of an Escherichia coli system for cell-free synthesis of selectively N-labelled proteins for rapid analysis by NMR spectroscopy.
European journal of biochemistry / FEBS 2004;271(20):4084-93.
2004: Pintacuda Guido; Moshref Ahmad; Leonchiks Ainars; Sharipo Anatoly; Otting Gottfried
Site-specific labelling with a metal chelator for protein-structure refinement.
Journal of biomolecular NMR 2004;29(3):351-61.
2004: Pintacuda Guido; Keniry Max A; Huber Thomas; Park Ah Young; Dixon Nicholas E; Otting Gottfried
Fast structure-based assignment of 15N HSQC spectra of selectively 15N-labeled paramagnetic proteins.
Journal of the American Chemical Society 2004;126(9):2963-70.
2004: Loscha Karin; Oakley Aaron J; Bancia Bogdan; Schaeffer Patrick M; Prosselkov Pavel; Otting Gottfried; Wilce Matthew C J; Dixon Nicholas E
Expression, purification, crystallization, and NMR studies of the helicase interaction domain of Escherichia coli DnaG primase.
Protein expression and purification 2004;33(2):304-10.
2004: Modig Kristofer; Liepinsh Edvards; Otting Gottfried; Halle Bertil
Dynamics of protein and peptide hydration.
Journal of the American Chemical Society 2004;126(1):102-14.
2003: Usami Shin-ichi; Takahashi Kentaro; Yuge Isamu; Ohtsuka Akihiro; Namba Atsushi; Abe Satoko; Fransen Erik; Patthy Laszlo; Otting Gottfried; Van Camp Guy
Mutations in the COCH gene are a frequent cause of autosomal dominant progressive cochleo-vestibular dysfunction, but not of Meniere's disease.
European journal of human genetics : EJHG 2003;11(10):744-8.
2003: Liepinsh Edvards; Barbals Raitis; Dahl Edgar; Sharipo Anatoly; Staub Eike; Otting Gottfried
The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition.
Journal of molecular biology 2003;332(5):1155-63.
2003: Pintacuda Guido; Hohenthanner Karin; Otting Gottfried; Müller Norbert
Angular dependence of dipole-dipole-Curie-spin cross-correlation effects in high-spin and low-spin paramagnetic myoglobin.
Journal of biomolecular NMR 2003;27(2):115-32.
2003: Liepinsh Edvards; Banyai Laszlo; Pintacuda Guido; Trexler Maria; Patthy Laszlo; Otting Gottfried
NMR structure of the netrin-like domain (NTR) of human type I procollagen C-proteinase enhancer defines structural consensus of NTR domains and assesses potential proteinase inhibitory activity and ligand binding.
The Journal of biological chemistry 2003;278(28):25982-9.
2003: Liepinsh Edvards; Généreux Catherine; Dehareng Dominique; Joris Bernard; Otting Gottfried
NMR structure of Citrobacter freundii AmpD, comparison with bacteriophage T7 lysozyme and homology with PGRP domains.
Journal of molecular biology 2003;327(4):833-42.
2003: Liepinsh Edvards; Leonchiks Ainars; Sharipo Anatoly; Guignard Laurent; Otting Gottfried
Solution structure of the R3H domain from human Smubp-2.
Journal of molecular biology 2003;326(1):217-23.
2002: Guignard Laurent; Ozawa Kiyoshi; Pursglove Sharon E; Otting Gottfried; Dixon Nicholas E
NMR analysis of in vitro-synthesized proteins without purification: a high-throughput approach.
FEBS letters 2002;524(1-3):159-62.
2002: Bellanda Massimo; Peggion Evaristo; Otting Gottfried; Weigelt Johan; Perdona Elisabetta; Domenici Enrico; Marchioro Carla; Mammi Stefano
Backbone 1H, 13C and 15N resonance assignment of the N-terminal 24 kDa fragment of the gyrase B subunit from E. coli.
Journal of biomolecular NMR 2002;22(4):369-70.
2002: Williams Neal K; Prosselkov Pavel; Liepinsh Edvards; Line Inara; Sharipo Anatoly; Littler Dene R; Curmi Paul M G; Otting Gottfried; Dixon Nicholas E
In vivo protein cyclization promoted by a circularly permuted Synechocystis sp. PCC6803 DnaB mini-intein.
The Journal of biological chemistry 2002;277(10):7790-8.
2002: Liepinsh Edvards; Otting Gottfried; Harding Margaret M; Ward Leanne G; Mackay Joel P; Haymet A D J
Solution structure of a hydrophobic analogue of the winter flounder antifreeze protein.
European journal of biochemistry / FEBS 2002;269(4):1259-66.
2002: Pintacuda Guido; Otting Gottfried
Identification of protein surfaces by NMR measurements with a pramagnetic Gd(III) chelate.
Journal of the American Chemical Society 2002;124(3):372-3.
2001: Liepinsh E; Trexler M; Kaikkonen A; Weigelt J; Bányai L; Patthy L; Otting G
NMR structure of the LCCL domain and implications for DFNA9 deafness disorder.
The EMBO journal 2001;20(19):5347-53.
2001: Liepinsh E; Baryshev M; Sharipo A; Ingelman-Sundberg M; Otting G; Mkrtchian S
Thioredoxin fold as homodimerization module in the putative chaperone ERp29: NMR structures of the domains and experimental model of the 51 kDa dimer.
Structure (London, England : 1993) 2001;9(6):457-71.
2001: Kaikkonen A; Otting G
Sensitive 1H-31P correlations with 5' methylene protons of DNA via homonuclear double-quantum coherence.
Journal of biomolecular NMR 2001;19(3):273-7.
2001: Wilce J A; Vivian J P; Hastings A F; Otting G; Folmer R H; Duggin I G; Wake R G; Wilce M C
Structure of the RTP-DNA complex and the mechanism of polar replication fork arrest.
Nature structural biology 2001;8(3):206-10.
2001: Kaikkonen A; Otting G
Residual dipolar (1)H-(1)H couplings of methyl groups in weakly aligned proteins.
Journal of the American Chemical Society 2001;123(8):1770-1.
2000: Nordstrand K; Sandström A; Aslund F; Holmgren A; Otting G; Berndt K D
NMR structure of oxidized glutaredoxin 3 from Escherichia coli.
Journal of molecular biology 2000;303(3):423-32.
2000: Hamdan S; Brown S E; Thompson P R; Yang J Y; Carr P D; Ollis D L; Otting G; Dixon N E
Preliminary X-ray crystallographic and NMR studies on the exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III.
Journal of structural biology 2000;131(2):164-9.
2000: Andersson P; Otting G
Time-shared X(omega(1))-half-filter for improved sensitivity in subspectral editing.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2000;144(1):168-70.
2000: Otting G; Rückert M; Levitt M H; Moshref A
NMR experiments for the sign determination of homonuclear scalar and residual dipolar couplings.
Journal of biomolecular NMR 2000;16(4):343-6.
2000: Folmer R; Otting G
Sensitivity enhancement in (HCA)CONH experiments.
Journal of biomolecular NMR 2000;16(3):229-33.
1999: Miteva M; Andersson M; Karshikoff A; Otting G
Molecular electroporation: a unifying concept for the description of membrane pore formation by antibacterial peptides, exemplified with NK-lysin.
FEBS letters 1999;462(1-2):155-8.
1999: Weigelt J; Brown S E; Miles C S; Dixon N E; Otting G
NMR structure of the N-terminal domain of E. coli DnaB helicase: implications for structure rearrangements in the helicase hexamer.
Structure (London, England : 1993) 1999;7(6):681-90.
1999: Nordstrand K; Aslund F; Meunier S; Holmgren A; Otting G; Berndt K D
Direct NMR observation of the Cys-14 thiol proton of reduced Escherichia coli glutaredoxin-3 supports the presence of an active site thiol-thiolate hydrogen bond.
FEBS letters 1999;449(2-3):196-200.
1999: Ilag L L; Rottenberger C; Liepinsh E; Wellnhofer G; Rudert F; Otting G; Ilag L L
Selection of a peptide ligand to the p75 neurotrophin receptor death domain and determination of its binding sites by NMR.
Biochemical and biophysical research communications 1999;255(1):104-9.
1999: Nordstrand K; slund F; Holmgren A; Otting G; Berndt K D
NMR structure of Escherichia coli glutaredoxin 3-glutathione mixed disulfide complex: implications for the enzymatic mechanism.
Journal of molecular biology 1999;286(2):541-52.
1998: Leonchiks A; Liepinsh E; Barishev M; Sharipo A; Masucci M G; Otting G
Random coil conformation of a Gly/Ala-rich insert in IkappaB alpha excludes structural stabilization as the mechanism for protection against proteasomal degradation.
FEBS letters 1998;440(3):365-9.
1998: Andersson P; Weigelt J; Otting G
Spin-state selection filters for the measurement of heteronuclear one-bond coupling constants.
Journal of biomolecular NMR 1998;12(3):435-41.
1998: Bonvin A M; Sunnerhagen M; Otting G; van Gunsteren W F
Water molecules in DNA recognition II: a molecular dynamics view of the structure and hydration of the trp operator.
Journal of molecular biology 1998;282(4):859-73.
1998: Sunnerhagen M; Denisov V P; Venu K; Bonvin A M; Carey J; Halle B; Otting G
Water molecules in DNA recognition I: hydration lifetimes of trp operator DNA in solution measured by NMR spectroscopy.
Journal of molecular biology 1998;282(4):847-58.
1998: Ponstingl H; Otting G
Rapid measurement of scalar three-bond 1HN-1H alpha spin coupling constants in 15N-labelled proteins.
Journal of biomolecular NMR 1998;12(2):319-24.
1998: Andersson P; Nordstrand K; Sunnerhagen M; Liepinsh E; Turovskis I; Otting G
Heteronuclear correlation experiments for the determination of one-bond coupling constants.
Journal of biomolecular NMR 1998;11(4):445-50.
1998: Andersson P; Gsell B; Wipf B; Senn H; Otting G
HMQC and HSQC experiments with water flip-back optimized for large proteins.
Journal of biomolecular NMR 1998;11(3):279-88.
1998: Weigelt J; Miles C S; Dixon N E; Otting G
Backbone NMR assignments and secondary structure of the N-terminal domain of DnaB helicase from E. coli.
Journal of biomolecular NMR 1998;11(2):233-4.
1998: Liepinsh E; Kitamura M; Murakami T; Nakaya T; Otting G
Common ancestor of serine proteases and flavin-binding domains.
Nature structural biology 1998;5(2):102-3.
1997: Sunnerhagen M; Nilges M; Otting G; Carey J
Solution structure of the DNA-binding domain and model for the complex of multifunctional hexameric arginine repressor with DNA.
Nature structural biology 1997;4(10):819-26.
1997: Liepinsh E; Andersson M; Ruysschaert J M; Otting G
Saposin fold revealed by the NMR structure of NK-lysin.
Nature structural biology 1997;4(10):793-5.
1997: Liepinsh E; Ilag L L; Otting G; Ibáñez C F
NMR structure of the death domain of the p75 neurotrophin receptor.
The EMBO journal 1997;16(16):4999-5005.
1997: Otting G; Liepinsh E; Halle B; Frey U
NMR identification of hydrophobic cavities with low water occupancies in protein structures using small gas molecules.
Nature structural biology 1997;4(5):396-404.
1997: Ponstingl H; Otting G
NMR assignments, secondary structure and hydration of oxidized Escherichia coli flavodoxin.
European journal of biochemistry / FEBS 1997;244(2):384-99.
1997: Miles C S; Weigelt J; Stamford N P; Dammerova N; Otting G; Dixon N E
Precise limits of the N-terminal domain of DnaB helicase determined by NMR spectroscopy.
Biochemical and biophysical research communications 1997;231(1):126-30.
1996: Hammarström A; Berndt K D; Sillard R; Adermann K; Otting G
Solution structure of a naturally-occurring zinc-peptide complex demonstrates that the N-terminal zinc-binding module of the Lasp-1 LIM domain is an independent folding unit.
Biochemistry 1996;35(39):12723-32.
1996: Aslund F; Nordstrand K; Berndt K D; Nikkola M; Bergman T; Ponstingl H; Jörnvall H; Otting G; Holmgren A
Glutaredoxin-3 from Escherichia coli. Amino acid sequence, 1H AND 15N NMR assignments, and structural analysis.
The Journal of biological chemistry 1996;271(12):6736-45.
1996: Weigelt J; Hammarstroem A; Bermel W; Otting G
Removal of zero-quantum coherence in protein NMR spectra using SESAM decoupling and suppression of decoupling sidebands.
Journal of magnetic resonance. Series B 1996;110(2):219-24.
1996: Liepinsh E; Otting G
Proton exchange rates from amino acid side chains--implications for image contrast.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1996;35(1):30-42.
1996: Nordstrand K; Ponstingl H; Holmgren A; Otting G
Resonance assignment and structural analysis of acid denatured E. coli [U-15N]-glutaredoxin 3: use of 3D 15N-HSQC-(TOCSY-NOESY)-15N-HSQC.
European biophysics journal : EBJ 1996;24(3):179-84.
1995: Eliasson R; Reichard P; Mulliez E; Ollagnier S; Fontecave M; Liepinsh E; Otting G
The mechanism of the anaerobic Escherichia coli ribonucleotide reductase investigated with nuclear magnetic resonance spectroscopy.
Biochemical and biophysical research communications 1995;214(1):28-35.
1994: Gehring W J; Qian Y Q; Billeter M; Furukubo-Tokunaga K; Schier A F; Resendez-Perez D; Affolter M; Otting G; Wüthrich K
Homeodomain-DNA recognition.
Cell 1994;78(2):211-23.
1994: Liepinsh E; Leupin W; Otting G
Hydration of DNA in aqueous solution: NMR evidence for a kinetic destabilization of the minor groove hydration of d-(TTAA)2 versus d-(AATT)2 segments.
Nucleic acids research 1994;22(12):2249-54.
1994: Liepinsh E; Berndt K D; Sillard R; Mutt V; Otting G
Solution structure and dynamics of PEC-60, a protein of the Kazal type inhibitor family, determined by nuclear magnetic resonance spectroscopy.
Journal of molecular biology 1994;239(1):137-53.
1994: Sevilla-Sierra P; Otting G; Wüthrich K
Determination of the nuclear magnetic resonance structure of the DNA-binding domain of the P22 c2 repressor (1 to 76) in solution and comparison with the DNA-binding domain of the 434 repressor.
Journal of molecular biology 1994;235(3):1003-20.
1993: Billeter M; Qian Y Q; Otting G; Müller M; Gehring W; Wüthrich K
Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex.
Journal of molecular biology 1993;234(4):1084-93.
1993: Qian Y Q; Otting G; Billeter M; Müller M; Gehring W; Wüthrich K
Nuclear magnetic resonance spectroscopy of a DNA complex with the uniformly 13C-labeled Antennapedia homeodomain and structure determination of the DNA-bound homeodomain.
Journal of molecular biology 1993;234(4):1070-83.
1993: Brunne R M; Liepinsh E; Otting G; Wüthrich K; van Gunsteren W F
Hydration of proteins. A comparison of experimental residence times of water molecules solvating the bovine pancreatic trypsin inhibitor with theoretical model calculations.
Journal of molecular biology 1993;231(4):1040-8.
1993: Leiting B; De Francesco R; Tomei L; Cortese R; Otting G; Wüthrich K
The three-dimensional NMR-solution structure of the polypeptide fragment 195-286 of the LFB1/HNF1 transcription factor from rat liver comprises a nonclassical homeodomain.
The EMBO journal 1993;12(5):1797-803.
1993: Otting G; Liepinsh E; Wüthrich K
Disulfide bond isomerization in BPTI and BPTI(G36S): an NMR study of correlated mobility in proteins.
Biochemistry 1993;32(14):3571-82.
1993: Liepinsh E; Rink H; Otting G; Wüthrich K
Contributions from hydration of carboxylate groups to the spectrum of water-polypeptide proton-proton Overhauser effects in aqueous solution.
Journal of biomolecular NMR 1993;3(2):253-7.
1993: Szyperski T; Luginbühl P; Otting G; Güntert P; Wüthrich K
Protein dynamics studied by rotating frame 15N spin relaxation times.
Journal of biomolecular NMR 1993;3(2):151-64.
1992: Liepinsh E; Otting G; Wüthrich K
NMR observation of individual molecules of hydration water bound to DNA duplexes: direct evidence for a spine of hydration water present in aqueous solution.
Nucleic acids research 1992;20(24):6549-53.
1992: Qian Y Q; Otting G; Furukubo-Tokunaga K; Affolter M; Gehring W J; Wüthrich K
NMR structure determination reveals that the homeodomain is connected through a flexible linker to the main body in the Drosophila Antennapedia protein.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(22):10738-42.
1992: Liepinsh E; Otting G; Wüthrich K
NMR spectroscopy of hydroxyl protons in aqueous solutions of peptides and proteins.
Journal of biomolecular NMR 1992;2(5):447-65.
1992: Szyperski T; Neri D; Leiting B; Otting G; Wüthrich K
Support of 1H NMR assignments in proteins by biosynthetically directed fractional 13C-labeling.
Journal of biomolecular NMR 1992;2(4):323-34.
1992: Billeter M; Neri D; Otting G; Qian Y Q; Wüthrich K
Precise vicinal coupling constants 3JHN alpha in proteins from nonlinear fits of J-modulated [15N,1H]-COSY experiments.
Journal of biomolecular NMR 1992;2(3):257-74.
1992: Wüthrich K; Otting G; Liepinsh E
Protein hydration in aqueous solution.
Faraday discussions 1992;(93):35-45.
1991: Otting G; Liepinsh E; Wüthrich K
Protein hydration in aqueous solution.
Science (New York, N.Y.) 1991;254(5034):974-80.
1991: Otting G; Liepinsh E; Farmer B T; Wüthrich K
Protein hydration studied with homonuclear 3D 1H NMR experiments.
Journal of biomolecular NMR 1991;1(2):209-15.
1991: Affolter M; Percival-Smith A; Müller M; Billeter M; Qian Y Q; Otting G; Wüthrich K; Gehring W J
Similarities between the homeodomain and the Hin recombinase DNA-binding domain.
Cell 1991;64(5):879-80.
1991: Güntert P; Qian Y Q; Otting G; Müller M; Gehring W; Wüthrich K
Structure determination of the Antp (C39----S) homeodomain from nuclear magnetic resonance data in solution using a novel strategy for the structure calculation with the programs DIANA, CALIBA, HABAS and GLOMSA.
Journal of molecular biology 1991;217(3):531-40.
1990: Gehring W J; Müller M; Affolter M; Percival-Smith A; Billeter M; Qian Y Q; Otting G; Wüthrich K
The structure of the homeodomain and its functional implications.
Trends in genetics : TIG 1990;6(10):323-9.
1990: Otting G; Qian Y Q; Billeter M; Müller M; Affolter M; Gehring W J; Wüthrich K
Protein--DNA contacts in the structure of a homeodomain--DNA complex determined by nuclear magnetic resonance spectroscopy in solution.
The EMBO journal 1990;9(10):3085-92.
1990: Billeter M; Qian Y; Otting G; Müller M; Gehring W J; Wüthrich K
Determination of the three-dimensional structure of the Antennapedia homeodomain from Drosophila in solution by 1H nuclear magnetic resonance spectroscopy.
Journal of molecular biology 1990;214(1):183-97.
1990: Leupin W; Otting G; Amacker H; Wüthrich K
Application of 13C(omega 1)-half-filtered [1H,1H]-NOESY for studies of a complex formed between DNA and a 13C-labeled minor-groove-binding drug.
FEBS letters 1990;263(2):313-6.
1989: Qian Y Q; Billeter M; Otting G; Müller M; Gehring W J; Wüthrich K
The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: comparison with prokaryotic repressors.
Cell 1989;59(3):573-80.
1989: Neri D; Szyperski T; Otting G; Senn H; Wüthrich K
Stereospecific nuclear magnetic resonance assignments of the methyl groups of valine and leucine in the DNA-binding domain of the 434 repressor by biosynthetically directed fractional 13C labeling.
Biochemistry 1989;28(19):7510-6.
1988: Otting G; Qian Y Q; Müller M; Affolter M; Gehring W; Wüthrich K
Secondary structure determination for the Antennapedia homeodomain by nuclear magnetic resonance and evidence for a helix-turn-helix motif.
The EMBO journal 1988;7(13):4305-9.
1988: Müller M; Affolter M; Leupin W; Otting G; Wüthrich K; Gehring W J
Isolation and sequence-specific DNA binding of the Antennapedia homeodomain.
The EMBO journal 1988;7(13):4299-304.
1988: Grütter R; Otting G; Wüthrich K; Leupin W
OR3 operator of bacteriophage lambda in a 23 base-pair DNA fragment: sequence-specific 1H NMR assignments for the non-labile protons and comparison with the isolated 17 base-pair operator.
European biophysics journal : EBJ 1988;16(5):279-86.
1987: Otting G; Marchot P; Bougis P E; Rochat H; Wüthrich K
Monitoring the purification by high-performance liquid chromatography of cardiotoxins from Naja mossambica mossambica using phase-sensitive two-dimensional nuclear magnetic resonance.
European journal of biochemistry / FEBS 1987;168(3):603-7.
1987: Otting G; Steinmetz W E; Bougis P E; Rochat H; Wüthrich K
Sequence-specific 1H-NMR assignments and determination of the secondary structure in aqueous solution of the cardiotoxins CTXIIa and CTXIIb from Naja mossambica mossambica.
European journal of biochemistry / FEBS 1987;168(3):609-20.
1987: Otting G; Grütter R; Leupin W; Minganti C; Ganesh K N; Sproat B S; Gait M J; Wüthrich K
Sequential NMR assignments of labile protons in DNA using two-dimensional nuclear-Overhauser-enhancement spectroscopy with three jump-and-return pulse sequences.
European journal of biochemistry / FEBS 1987;166(1):215-20.
1987: Senn H; Eugster A; Otting G; Suter F; Wüthrich K
15N-labeled P22 c2 repressor for nuclear magnetic resonance studies of protein-DNA interactions.
European biophysics journal : EBJ 1987;14(5):301-6.

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