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Michael Ottolenghi

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TOP 3
Nir Friedman; Michael Ottolenghi; Mordechai Sheves
Heterogeneity effects in the binding of all-trans retinal to bacterio-opsin.
Uri Zadok; Artium Khatchatouriants; Aaron Lewis; Michael Ottolenghi; Mordechai Sheves
Light-induced charge redistribution in the retinal chromophore is required for initiating the bacteriorhodopsin photocycle.
Sanford Ruhman; Bixue Hou; Nir Friedman; Michael Ottolenghi; Mordechai Sheves
Following evolution of bacteriorhodopsin in its reactive excited state via stimulated emission pumping.

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All Publications

2003: Nir Friedman; Michael Ottolenghi; Mordechai Sheves
Heterogeneity effects in the binding of all-trans retinal to bacterio-opsin.
Biochemistry 2003;42(38):11281-8.
2002: Uri Zadok; Artium Khatchatouriants; Aaron Lewis; Michael Ottolenghi; Mordechai Sheves
Light-induced charge redistribution in the retinal chromophore is required for initiating the bacteriorhodopsin photocycle.
Journal of the American Chemical Society 2002;124(40):11844-5.
2002: Sanford Ruhman; Bixue Hou; Nir Friedman; Michael Ottolenghi; Mordechai Sheves
Following evolution of bacteriorhodopsin in its reactive excited state via stimulated emission pumping.
Journal of the American Chemical Society 2002;124(30):8854-8.
2002: Asaph Aharoni; Michael Ottolenghi; Mordechai Sheves
Photoreduction of bacteriorhodopsin Schiff base at low humidity. A study with C13=C14 nonisomerizable artificial pigments.
Photochemistry and photobiology 2002;75(6):668-74.
2002: Asaph Aharoni; Michael Ottolenghi; Mordechai Sheves
Light-induced hydrolysis and rebinding of nonisomerizable bacteriorhodopsin pigment.
Biophysical journal 2002;82(5):2617-26.
2001: Asaph Aharoni; Michael Ottolenghi; Mordechai Sheves
Retinal isomerization in bacteriorhodopsin is controlled by specific chromophore-protein interactions. A study with noncovalent artificial pigments.
Biochemistry 2001;40(44):13310-9.
2001: Asaph Aharoni; B Hou; Nir Friedman; Michael Ottolenghi; Itay Rousso; Sanford Ruhman; Mordechai Sheves; T Ye; Q Zhong
Non-isomerizable artificial pigments: implications for the primary light-induced events in bacteriorhodopsin.
Biochemistry. Biokhimii͡a 2001;66(11):1210-9.
2001: T Eliash; Lev Weiner; Michael Ottolenghi; Mordechai Sheves
Specific binding sites for cations in bacteriorhodopsin.
Biophysical journal 2001;81(2):1155-62.
2001: Asaph Aharoni; Lev Weiner; Aaron Lewis; Michael Ottolenghi; Mordechai Sheves
Nonisomerizable non-retinal chromophores initiate light-induced conformational alterations in bacterioopsin.
Journal of the American Chemical Society 2001;123(27):6612-6.
2000: Asaph Aharoni; Lev Weiner; Michael Ottolenghi; Mordechai Sheves
Bacteriorhodpsin experiences light-induced conformational alterations in nonisomerizable C(13)=C(14) pigments. A study with EPR.
The Journal of biological chemistry 2000;275(28):21010-6.
2000: Q Li; S Bressler; D Ovrutsky; Michael Ottolenghi; Nir Friedman; Mordechai Sheves
On the protein residues that control the yield and kinetics of O(630) in the photocycle of bacteriorhodopsin.
Biophysical journal 2000;78(1):354-62.
1999: T Eliash; Michael Ottolenghi; Mordechai Sheves
The titrations of Asp-85 and of the cation binding residues in bacteriorhodopsin are not coupled.
FEBS letters 1999;447(2-3):307-10.
1999: S Bressler; Nir Friedman; Q Li; Michael Ottolenghi; C Saha; Mordechai Sheves
Generation of the O630 photointermediate of bacteriorhodopsin is controlled by the state of protonation of several protein residues.
Biochemistry 1999;38(7):2018-25.
1998: Itay Rousso; Y Gat; Aaron Lewis; Mordechai Sheves; Michael Ottolenghi
Effective light-induced hydroxylamine reactions occur with C13 = C14 nonisomerizable bacteriorhodopsin pigments.
Biophysical journal 1998;75(1):413-7.
1997: X Fu; S Bressler; Michael Ottolenghi; T Eliash; Nir Friedman; Mordechai Sheves
Titration kinetics of Asp-85 in bacteriorhodopsin: exclusion of the retinal pocket as the color-controlling cation binding site.
FEBS letters 1997;416(2):167-70.
1997: Nir Friedman; Itay Rousso; Mordechai Sheves; X Fu; S Bressler; S Druckmann; Michael Ottolenghi
Time-resolved titrations of ASP-85 in bacteriorhodopsin: the multicomponent kinetic mechanism.
Biochemistry 1997;36(38):11369-80.
1997: Itay Rousso; E Khachatryan; Y Gat; I Brodsky; Michael Ottolenghi; Mordechai Sheves; Aaron Lewis
Microsecond atomic force sensing of protein conformational dynamics: implications for the primary light-induced events in bacteriorhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(15):7937-41.
1997: Y Gat; Nir Friedman; Mordechai Sheves; Michael Ottolenghi
Interaction between Asp-85 and the proton-releasing group in bacteriorhodopsin. A study of an O-like photocycle intermediate.
Biochemistry 1997;36(14):4135-48.
1997: S Shalom; A Strinkovski; G Peleg; S Druckmann; A Krauss; Aaron Lewis; M Linial; Michael Ottolenghi
An optical submicrometer calcium sensor with conductance sensing capability.
Analytical biochemistry 1997;244(2):256-9.
1996: Yechezkel Barenholz; T Cohen; E Haas; Michael Ottolenghi
Lateral organization of pyrene-labeled lipids in bilayers as determined from the deviation from equilibrium between pyrene monomers and excimers.
The Journal of biological chemistry 1996;271(6):3085-90.
1995: S Druckmann; Michael Ottolenghi; Itay Rousso; Nir Friedman; Mordechai Sheves
Time-resolved titrations of the Schiff base and of the Asp85 residue in artificial bacteriorhodopsins.
Biochemistry 1995;34(37):12066-74.
1995: Itay Rousso; Nir Friedman; Mordechai Sheves; Michael Ottolenghi
pKa of the protonated Schiff base and aspartic 85 in the bacteriorhodopsin binding site is controlled by a specific geometry between the two residues.
Biochemistry 1995;34(37):12059-65.
1995: T L Mah; James W Lewis; Mordechai Sheves; Michael Ottolenghi; David S Kliger
Low-temperature trapping of early photointermediates of alpha-isorhodopsin.
Photochemistry and photobiology 1995;62(2):356-60.
1995: J K Delaney; T L Brack; G H Atkinson; Michael Ottolenghi; G Steinberg; Mordechai Sheves
Primary picosecond molecular events in the photoreaction of the BR5.12 artificial bacteriorhodopsin pigment.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(6):2101-5.
1994: Nir Friedman; Y Gat; Mordechai Sheves; Michael Ottolenghi
On the heterogeneity of the M population in the photocycle of bacteriorhodopsin.
Biochemistry 1994;33(49):14758-67.
1994: G Steinberg; Mordechai Sheves; S Bressler; Michael Ottolenghi
Factors affecting the formation of an M-like intermediate in the photocycle of 13-cis-bacteriorhodopsin.
Biochemistry 1994;33(41):12439-50.
1994: Nir Friedman; S Druckmann; J Lanyi; Richard Needleman; Aaron Lewis; Michael Ottolenghi; Mordechai Sheves
A covalent link between the chromophore and the protein backbone of bacteriorhodopsin is not required for forming a photochemically active pigment analogous to the wild type.
Biochemistry 1994;33(8):1971-6.
1993: S Druckmann; M P Heyn; J K Lanyi; Michael Ottolenghi; L Zimanyi
Thermal equilibration between the M and N intermediates in the photocycle of bacteriorhodopsin.
Biophysical journal 1993;65(3):1231-4.
1993: Leonid S Brown; László Zimányi; Richard Needleman; Michael Ottolenghi; Janos K Lanyi
Photoreaction of the N intermediate of bacteriorhodopsin, and its relationship to the decay kinetics of the M intermediate.
Biochemistry 1993;32(30):7679-85.
1993: László Zimányi; Y Cao; Richard Needleman; Michael Ottolenghi; Janos K Lanyi
Pathway of proton uptake in the bacteriorhodopsin photocycle.
Biochemistry 1993;32(30):7669-78.
1993: T L Brack; J K Delaney; G H Atkinson; A Albeck; Mordechai Sheves; Michael Ottolenghi
Picosecond time-resolved absorption and fluorescence dynamics in the artificial bacteriorhodopsin pigment BR6.11.
Biophysical journal 1993;65(2):964-72.
1993: G Steinberg; Michael Ottolenghi; Mordechai Sheves
pKa of the protonated Schiff base of bovine rhodopsin. A study with artificial pigments.
Biophysical journal 1993;64(5):1499-502.
1992: S Shtelzer; S Rappoport; D Avnir; Michael Ottolenghi; S Braun
Properties of trypsin and of acid phosphatase immobilized in sol-gel glass matrices.
Biotechnology and applied biochemistry 1992;15(3):227-35.
1992: S Druckmann; Nir Friedman; J K Lanyi; Richard Needleman; Michael Ottolenghi; Mordechai Sheves
The back photoreaction of the M intermediate in the photocycle of bacteriorhodopsin: mechanism and evidence for two M species.
Photochemistry and photobiology 1992;56(6):1041-7.
1991: Yechezkel Barenholz; T Cohen; R Korenstein; Michael Ottolenghi
Organization and dynamics of pyrene and pyrene lipids in intact lipid bilayers. Photo-induced charge transfer processes.
Biophysical journal 1991;60(1):110-24.
1991: Nir Friedman; Mordechai Sheves; Michael Ottolenghi
Population of the triplet states of bacteriorhodopsin and of related model compounds by intramolecular energy transfer.
Biochemistry 1991;30(22):5400-6.
1989: Michael Ottolenghi; Mordechai Sheves
Synthetic retinals as probes for the binding site and photoreactions in rhodopsins.
The Journal of membrane biology 1989;112(3):193-212.
1989: A Albeck; Nir Friedman; Mordechai Sheves; Michael Ottolenghi
Factors affecting the absorption maxima of acidic forms of bacteriorhodopsin. A study with artificial pigments.
Biophysical journal 1989;56(6):1259-65.
1989: A Albeck; Nir Friedman; Michael Ottolenghi; Mordechai Sheves; C M Einterz; S J Hug; James W Lewis; David S Kliger
Photolysis intermediates of the artificial visual pigment cis-5,6-dihydro-isorhodopsin.
Biophysical journal 1989;55(2):233-41.
1986: Mordechai Sheves; A Albeck; Nir Friedman; Michael Ottolenghi
Controlling the pKa of the bacteriorhodopsin Schiff base by use of artificial retinal analogues.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(10):3262-6.
1985: S Druckmann; Michael Ottolenghi; R Korenstein
Time-resolved absorbance changes induced by fast acidification of bacteriorhodopsin in vesicle systems.
Biophysical journal 1985;47(1):115-8.
1984: S Druckmann; Robert Renthal; Michael Ottolenghi; W Stoeckenius
The radiolytic reduction of the Schiff base in bacteriorhodopsin.
Photochemistry and photobiology 1984;40(5):647-51.
1982: S Druckmann; Michael Ottolenghi; A Pande; J Pande; Robert Callender
Acid-base equilibrium of the Schiff base in bacteriorhodopsin.
Biochemistry 1982;21(20):4953-9.
1981: O Kalisky; Michael Ottolenghi; B Honig; R Korenstein
Environmental effects on formation and photoreaction of the M412 photoproduct of bacteriorhodopsin: implications for the mechanism of proton pumping.
Biochemistry 1981;20(3):649-55.
1981: B J Litman; O Kalisky; Michael Ottolenghi
Rhodopsin-phospholipid interactions: dependence of rate of the meta I to meta II transition on the level of associated disk phospholipid.
Biochemistry 1981;20(3):631-4.
1981: A G Doukas; A Pande; T Suzuki; Robert Callender; B Honig; Michael Ottolenghi
On the mechanism of hydrogen-deuterium exchange in bacteriorhodopsin.
Biophysical journal 1981;33(2):275-9.
1981: S Druckmann; Michael Ottolenghi
Electric dichroism in the purple membrane of Halobacterium halobium.
Biophysical journal 1981;33(2):263-8.
1981: O Kalisky; J Feitelson; Michael Ottolenghi
Photochemistry and fluorescence of bacteriorhodopsin excited in its 280-nm absorption band.
Biochemistry 1981;20(1):205-9.