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Paul Overbeek

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Tyler F Beck; Colin Bishop; Andres Hernandez-Garcia; Monica J Justice; Bum Jun Kim; Paul A Overbeek; Oleg A Shchelochkov; David Wayne Stockton; Zhiyin Yu; Hitisha P Zaveri; Daryl A Scott
Novel frem1-related mouse phenotypes and evidence of genetic interactions with gata4 and slit3.
Irina V Larina; Paul A Overbeek; Narendran Sudheendran; Saba H Syed; Mary E Dickinson; Kirill V Larin
Optical coherence tomography for live phenotypic analysis of embryonic ocular structures in mouse models.
Giuseppina Somma; Pawel Stankiewicz; Svetlana A Yatsenko; Fernanda R Ruiz; Heather Alger; Antonio Bergamaschi; Etai Funk; Wilbur Harrison; Jim D Kretlow; Ryan M McGuire; Antonios G Mikos; John S Oghalai; Paul A Overbeek; Fred A Pereira
Head bobber: an insertional mutation causes inner ear defects, hyperactive circling, and deafness.

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All Publications

2013: Tyler F Beck; Colin Bishop; Andres Hernandez-Garcia; Monica J Justice; Bum Jun Kim; Paul A Overbeek; Oleg A Shchelochkov; David Wayne Stockton; Zhiyin Yu; Hitisha P Zaveri; Daryl A Scott
Novel frem1-related mouse phenotypes and evidence of genetic interactions with gata4 and slit3.
PloS one 2013;8(3):e58830.
2012: Irina V Larina; Paul A Overbeek; Narendran Sudheendran; Saba H Syed; Mary E Dickinson; Kirill V Larin
Optical coherence tomography for live phenotypic analysis of embryonic ocular structures in mouse models.
Journal of biomedical optics 2012;17(8):081410-1.
2012: Giuseppina Somma; Pawel Stankiewicz; Svetlana A Yatsenko; Fernanda R Ruiz; Heather Alger; Antonio Bergamaschi; Etai Funk; Wilbur Harrison; Jim D Kretlow; Ryan M McGuire; Antonios G Mikos; John S Oghalai; Paul A Overbeek; Fred A Pereira
Head bobber: an insertional mutation causes inner ear defects, hyperactive circling, and deafness.
Journal of the Association for Research in Otolaryngology : JARO 2012;13(3):335-49.
2012: Jianning Tao; Dennis R Roop; David R Beier; Wilbur Harrison; Maranke I Koster; Jennifer L Moran; Paul A Overbeek
A spontaneous Fatp4/Scl27a4 splice site mutation in a new murine model for congenital ichthyosis.
PloS one 2012;7(11):e50634.
2011: Baiping Wang; Wilbur Harrison; Paul A Overbeek; Hui Zheng
Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development.
Development (Cambridge, England) 2011;138(20):4487-97.
2011: Lixing W Reneker; Huiyi Chen; Paul A Overbeek
Activation of unfolded protein response in transgenic mouse lenses.
Investigative ophthalmology & visual science 2011;52(5):2100-8.
2011: Shannon M Hamilton; Corinne M Spencer; Wilbur R Harrison; Lisa A Yuva-Paylor; Deanna F Graham; Ray A M Daza; Robert Hevner; Paul A Overbeek; Richard Paylor
Multiple autism-like behaviors in a novel transgenic mouse model.
Behavioural brain research 2011;218(1):29-41.
2010: Jinrong Wang; Yin Wang; Jianyin Long; Benny Hung-Junn Chang; Mathew H Wilson; Paul A Overbeek; Farhad R Danesh
Tamoxifen-inducible podocyte-specific iCre recombinase transgenic mouse provides a simple approach for modulation of podocytes in vivo.
Genesis (New York, N.Y. : 2000) 2010;48(7):446-51.
2010: Lixing W Reneker; Amy J. Bloch; Leike Xie; Paul A Overbeek; John D Ash
Induction of corneal myofibroblasts by lens-derived transforming growth factor beta1 (TGFbeta1): a transgenic mouse model.
Brain research bulletin 2010;81(2-3):287-96.
2010: Daniel Burgess; Yan Zhang; Ed Siefker; Ryan Vaca; Murali R Kuracha; Lixing Reneker; Paul A Overbeek; Venkatesh Govindarajan
Activated Ras alters lens and corneal development through induction of distinct downstream targets.
BMC developmental biology 2010;10():13.
2009: Jack Heath; Abigail K Langton; Nigel L Hammond; Paul A Overbeek; Michael J Dixon; Denis J Headon
Hair follicles are required for optimal growth during lateral skin expansion.
The Journal of investigative dermatology 2009;129(10):2358-64.
2008: Bruce A Boswell; Paul A Overbeek; Linda S Musil
Essential role of BMPs in FGF-induced secondary lens fiber differentiation.
Developmental biology 2008;324(2):202-12.
2008: Yan Zhang; Daniel Burgess; Paul A Overbeek; Venkatesh Govindarajan
Dominant inhibition of lens placode formation in mice.
Developmental biology 2008;323(1):53-63.
2007: Baisong Lu; Aron M Geurts; Christophe Poirier; Deborah C Petit; Wilbur Harrison; Paul A Overbeek; Jack alvarez
Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system.
Mammalian genome : official journal of the International Mammalian Genome Society 2007;18(5):338-46.
2007: Yan Zhang; Paul A Overbeek; Venkatesh Govindarajan
Perinatal ablation of the mouse lens causes multiple anterior chamber defects.
Molecular vision 2007;13():2289-300.
2007: Leike Xie; Huiyi Chen; Paul A Overbeek; Lixing W Reneker
Elevated insulin signaling disrupts the growth and differentiation pattern of the mouse lens.
Molecular vision 2007;13():397-407.
2006: Leike Xie; Paul A Overbeek; Lixing W Reneker
Ras signaling is essential for lens cell proliferation and lens growth during development.
Developmental biology 2006;298(2):403-14.
2006: Chunyan Mou; Ben Jackson; Pascal Schneider; Paul A Overbeek; Denis J Headon
Generation of the primary hair follicle pattern.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9075-80.
2006: Venkatesh Govindarajan; Paul A Overbeek
FGF9 can induce endochondral ossification in cranial mesenchyme.
BMC developmental biology 2006;6():7.
2005: Dianca R Graham; Paul A Overbeek; John D Ash
Leukemia inhibitory factor blocks expression of Crx and Nrl transcription factors to inhibit photoreceptor differentiation.
Investigative ophthalmology & visual science 2005;46(7):2601-10.
2005: Venkatesh Govindarajan; Wilbur R Harrison; Ningna Xiao; Dongcai Liang; Paul A Overbeek
Intracorneal positioning of the lens in Pax6-GAL4/VP16 transgenic mice.
Molecular vision 2005;11():876-86.
2004: Lixing W Reneker; Qin Chen; Amy J. Bloch; Leike Xie; Gaby Schuster; Paul A Overbeek
Chick delta1-crystallin enhancer influences mouse alphaA-crystallin promoter activity in transgenic mice.
Investigative ophthalmology & visual science 2004;45(11):4083-90.
2004: Tao Yang; Dongcai Liang; Peter J Koch; Daniel Hohl; Farrah Kheradmand; Paul A Overbeek
Epidermal detachment, desmosomal dissociation, and destabilization of corneodesmosin in Spink5-/- mice.
Genes & development 2004;18(19):2354-8.
2004: Yangjun Qin; Ling-kun Kong; Christophe Poirier; Cavatina Truong; Paul A Overbeek; Jack alvarez
Long-range activation of Sox9 in Odd Sex (Ods) mice.
Human molecular genetics 2004;13(12):1213-8.
2004: Haotian Zhao; Ying Yang; Christian M Rizo; Paul A Overbeek; Michael L Robinson
Insertion of a Pax6 consensus binding site into the alphaA-crystallin promoter acts as a lens epithelial cell enhancer in transgenic mice.
Investigative ophthalmology & visual science 2004;45(6):1930-9.
2004: Qin Chen; Dongcai Liang; Larry D Fromm; Paul A Overbeek
Inhibition of lens fiber cell morphogenesis by expression of a mutant SV40 large T antigen that binds CREB-binding protein/p300 but not pRb.
The Journal of biological chemistry 2004;279(17):17667-73.
2004: Abigail S Tucker; Denis J Headon; Jo-Maree Courtney; Paul A Overbeek; Paul T Sharpe
The activation level of the TNF family receptor, Edar, determines cusp number and tooth number during tooth development.
Developmental biology 2004;268(1):185-94.
2004: Lixing W Reneker; Leike Xie; Li Xu; Venkatesh Govindarajan; Paul A Overbeek
Activated Ras induces lens epithelial cell hyperplasia but not premature differentiation.
The International journal of developmental biology 2004;48(8-9):879-88.
2002: Shulei Zhao; Qin Chen; Fang-Cheng Hung; Paul A Overbeek
BMP signaling is required for development of the ciliary body.
Development (Cambridge, England) 2002;129(19):4435-42.
2002: Isabelle Daneau; Nicolas Pilon; Alexandre Boyer; Ramin Behdjani; Paul A Overbeek; Robert S Viger; Jacques G Lussier; David W Silversides
The porcine SRY promoter is transactivated within a male genital ridge environment.
Genesis (New York, N.Y. : 2000) 2002;33(4):170-80.
2002: Qin Chen; Dennis H Dowhan; Dongcai Liang; David D Moore; Paul A Overbeek
CREB-binding protein/p300 co-activation of crystallin gene expression.
The Journal of biological chemistry 2002;277(27):24081-9.
2002: Li Xu; Paul A Overbeek; Lixing W Reneker
Systematic analysis of E-, N- and P-cadherin expression in mouse eye development.
Experimental eye research 2002;74(6):753-60.
2002: David Cunningham; Qiang Xiao; Aurobindo Chatterjee; Kathleen K Sulik; Diana Juriloff; Frederick F Elder; Wilbur Harrison; Gabriele Schuster; Paul A Overbeek; Gail E Herman
exma: an X-linked insertional mutation that disrupts forebrain and eye development.
Mammalian genome : official journal of the International Mammalian Genome Society 2002;13(4):179-85.
2002: Qin Chen; John D Ash; Phil Branton; Larry D Fromm; Paul A Overbeek
Inhibition of crystallin expression and induction of apoptosis by lens-specific E1A expression in transgenic mice.
Oncogene 2002;21(7):1028-37.
2002: Fang-Cheng Hung; Shulei Zhao; Qin Chen; Paul A Overbeek
Retinal ablation and altered lens differentiation induced by ocular overexpression of BMP7.
Vision research 2002;42(4):427-38.
2002: Frank J Lovicu; Mark W Schulz; Angela M Hales; Lisa N Vincent; Paul A Overbeek; Coral G Chamberlain; John W McAvoy
TGFbeta induces morphological and molecular changes similar to human anterior subcapsular cataract.
The British journal of ophthalmology 2002;86(2):220-6.
2001: Denis J Headon; S A Emmal; Betsy M Ferguson; Abigail S Tucker; Monica J Justice; Paul T Sharpe; Jonathan (Jon) Zonana; Paul A Overbeek
Gene defect in ectodermal dysplasia implicates a death domain adapter in development.
Nature 2001;414(6866):913-6.
2001: Shulei Zhao; Paul A Overbeek
Regulation of choroid development by the retinal pigment epithelium.
Molecular vision 2001;7():277-82.
2001: Shulei Zhao; Fang-Cheng Hung; J S Colvin; A White; W Dai; Frank J Lovicu; David M Ornitz; Paul A Overbeek
Patterning the optic neuroepithelium by FGF signaling and Ras activation.
Development (Cambridge, England) 2001;128(24):5051-60.
2001: Robbert U de Iongh; Frank J Lovicu; Paul A Overbeek; M D Schneider; J Joya; E D Hardeman; John W McAvoy
Requirement for TGFbeta receptor signaling during terminal lens fiber differentiation.
Development (Cambridge, England) 2001;128(20):3995-4010.
2001: Shulei Zhao; Paul A Overbeek
Elevated TGFbeta signaling inhibits ocular vascular development.
Developmental biology 2001;237(1):45-53.
2001: Hidemasa Oh; George E Taffet; Keith A Youker; Mark L Entman; Paul A Overbeek; Lloyd H Michael; Michael D Schneider
Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10308-13.
2001: Paul A Overbeek; Ivan P Gorlov; Richard Sutherland; J B Houston; Wilbur R Harrison; Holly L Boettger-Tong; Jack alvarez; Alexander I Agoulnik
A transgenic insertion causing cryptorchidism in mice.
Genesis (New York, N.Y. : 2000) 2001;30(1):26-35.
2001: Venkatesh Govindarajan; Paul A Overbeek
Secreted FGFR3, but not FGFR1, inhibits lens fiber differentiation.
Development (Cambridge, England) 2001;128(9):1617-27.
2001: Rainer Döffinger; Asma Smahi; Christine Bessia; Frederic Geissmann; Jacqueline Feinberg; Anne Durandy; Christine Bodemer; Sue Kenwrick; Sophie Dupuis-Girod; Stéphane Blanche; P Wood; S H Rabia; Denis J Headon; Paul A Overbeek; Françoise Le Deist; Steven M Holland; K Belani; Dinakantha S Kumararatne; Alain Fischer; R Shapiro; M E Conley; E Reimund; H Kalhoff; M Abinun; Arnold Munnich; Alain Israël; Gilles Courtois; Jean-Laurent Casanova
X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling.
Nature genetics 2001;27(3):277-85.
2001: S Shirke; sonya faber; E Hallem; Helen P Makarenkova; Michael L Robinson; Paul A Overbeek; Richard Lang
Misexpression of IGF-I in the mouse lens expands the transitional zone and perturbs lens polarization.
Mechanisms of development 2001;101(1-2):167-74.
2000: Jack alvarez; D J Whitworth; Yangjun Qin; Alexander I Agoulnik; Irina U Agoulnik; Wilbur R Harrison; Richard R Behringer; Paul A Overbeek
A transgenic insertion upstream of sox9 is associated with dominant XX sex reversal in the mouse.
Nature genetics 2000;26(4):490-4.
2000: Qin Chen; Fang-Cheng Hung; Larry D Fromm; Paul A Overbeek
Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2.
Investigative ophthalmology & visual science 2000;41(13):4223-31.
2000: Abigail S Tucker; Denis J Headon; Pascal Schneider; Betsy M Ferguson; Paul A Overbeek; Jürg Tschopp; Paul T Sharpe
Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis.
Development (Cambridge, England) 2000;127(21):4691-700.
2000: Venkatesh Govindarajan; Masataka Ito; Helen P Makarenkova; Richard Lang; Paul A Overbeek
Endogenous and ectopic gland induction by FGF-10.
Developmental biology 2000;225(1):188-200.
2000: J D Ash; Paul A Overbeek
Lens-specific VEGF-A expression induces angioblast migration and proliferation and stimulates angiogenic remodeling.
Developmental biology 2000;223(2):383-98.
2000: Helen P Makarenkova; Masataka Ito; Venkatesh Govindarajan; sonya faber; L Sun; G McMahon; Paul A Overbeek; Richard Lang
FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development.
Development (Cambridge, England) 2000;127(12):2563-72.
2000: D Zhang; Vinciane Gaussin; George E Taffet; Narasimhaswamy S Belaguli; M Yamada; Robert J Schwartz; Lloyd H Michael; Paul A Overbeek; Michael D Schneider
TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice.
Nature medicine 2000;6(5):556-63.
2000: Lixing W Reneker; David W Silversides; Li Xu; Paul A Overbeek
Formation of corneal endothelium is essential for anterior segment development - a transgenic mouse model of anterior segment dysgenesis.
Development (Cambridge, England) 2000;127(3):533-42.
1999: Shulei Zhao; Paul A Overbeek
Tyrosinase-related protein 2 promoter targets transgene expression to ocular and neural crest-derived tissues.
Developmental biology 1999;216(1):154-63.
1999: Frank J Lovicu; W W Kao; Paul A Overbeek
Ectopic gland induction by lens-specific expression of keratinocyte growth factor (FGF-7) in transgenic mice.
Mechanisms of development 1999;88(1):43-53.
1999: Denis J Headon; Paul A Overbeek
Involvement of a novel Tnf receptor homologue in hair follicle induction.
Nature genetics 1999;22(4):370-4.
1999: A W Monreal; Betsy M Ferguson; Denis J Headon; S L Street; Paul A Overbeek; Jonathan (Jon) Zonana
Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia.
Nature genetics 1999;22(4):366-9.
1999: Margaret L Sutherland; S H Williams; R Abedi; Paul A Overbeek; Paul J Pfaffinger; Jeffrey L Noebels
Overexpression of a Shaker-type potassium channel in mammalian central nervous system dysregulates native potassium channel gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2451-5.
1998: K Majumder; W Shawlot; Gabriele Schuster; Wilbur Harrison; Frederick F Elder; Paul A Overbeek
YAC rescue of downless locus mutations in mice.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;9(11):863-8.
1998: D Morgan; Lee Turnpenny; Judith A Goodship; W Dai; K Majumder; L Matthews; A Gardner; Gabriele Schuster; L Vien; Wilbur Harrison; Frederick F Elder; M Penman Splitt; Paul A Overbeek; Tom Strachan
Inversin, a novel gene in the vertebrate left-right axis pathway, is partially deleted in the inv mouse.
Nature genetics 1998;20(2):149-56.
1998: Frank J Lovicu; Paul A Overbeek
Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice.
Development (Cambridge, England) 1998;125(17):3365-77.
1998: MJ Charng; PA Frenkel; Q Lin; M Yamada; Robert J Schwartz; Eric N Olson; Paul A Overbeek; Michael D Schneider; M Yumada
A constitutive mutation of ALK5 disrupts cardiac looping and morphogenesis in mice.
Developmental biology 1998;199(1):72-9.
1998: Michael L Robinson; C Ohtaka-Maruyama; C C Chan; S Jamieson; C Dickson; Paul A Overbeek; Ana B Chepelinsky
Disregulation of ocular morphogenesis by lens-specific expression of FGF-3/int-2 in transgenic mice.
Developmental biology 1998;198(1):13-31.
1998: Y Srinivasan; Frank J Lovicu; Paul A Overbeek
Lens-specific expression of transforming growth factor beta1 in transgenic mice causes anterior subcapsular cataracts.
The Journal of clinical investigation 1998;101(3):625-34.
1997: R Agah; PA Frenkel; B A French; Lloyd H Michael; Paul A Overbeek; Michael D Schneider
Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.
The Journal of clinical investigation 1997;100(1):169-79.
1997: Larry D Fromm; Paul A Overbeek
Inhibition of cell death by lens-specific overexpression of bcl-2 in transgenic mice.
Developmental genetics 1997;20(3):276-87.
1996: L W Reneker; Paul A Overbeek
Lens-specific expression of PDGF-A alters lens growth and development.
Developmental biology 1996;180(2):554-65.
1996: L W Reneker; Paul A Overbeek
Lens-specific expression of PDGF-A in transgenic mice results in retinal astrocytic hamartomas.
Investigative ophthalmology & visual science 1996;37(12):2455-66.
1996: M L Robinson; Paul A Overbeek
Differential expression of alpha A- and alpha B-crystallin during murine ocular development.
Investigative ophthalmology & visual science 1996;37(11):2276-84.
1996: Y Zhou; Paul A Overbeek; Kenneth E Bernstein
Tissue specific expression of testis angiotensin converting enzyme is not determined by the -32 nonconsensus TATA motif.
Biochemical and biophysical research communications 1996;223(1):48-53.
1996: Dennis M Marcus; J G Lasudry; J L Carpenter; Jolene J Windle; Kimberly Howes; Muayyad R Al-Ubaidi; Wolfgang Baehr; Paul A Overbeek; Ramon L Font; Daniel M Albert
Trilateral tumors in four different lines of transgenic mice expressing SV40 T-antigen.
Investigative ophthalmology & visual science 1996;37(2):392-6.
1996: L Fromm; Paul A Overbeek
Regulation of cyclin and cyclin-dependent kinase gene expression during lens differentiation requires the retinoblastoma protein.
Oncogene 1996;12(1):69-75.
1995: M L Robinson; L A MacMillan-Crow; J A Thompson; Paul A Overbeek
Expression of a truncated FGF receptor results in defective lens development in transgenic mice.
Development (Cambridge, England) 1995;121(12):3959-67.
1995: L W Reneker; D W Silversides; K Patel; Paul A Overbeek
TGF alpha can act as a chemoattractant to perioptic mesenchymal cells in developing mouse eyes.
Development (Cambridge, England) 1995;121(6):1669-80.
1995: D L Schaffner; Roberto Barrios; M R Shaker; S Rajagopalan; S L Huang; D J Tindall; Charles Y F Young; Paul A Overbeek; RM Lebovitz; Michael W Lieberman
Transgenic mice carrying a PSArasT24 hybrid gene develop salivary gland and gastrointestinal tract neoplasms.
Laboratory investigation; a journal of technical methods and pathology 1995;72(3):283-90.
1995: M L Robinson; Paul A Overbeek; D J Verran; W E Grizzle; C R Stockard; R Friesel; T Maciag; J A Thompson
Extracellular FGF-1 acts as a lens differentiation factor in transgenic mice.
Development (Cambridge, England) 1995;121(2):505-14.
1994: L Fromm; W Shawlot; K Gunning; Janet S Butel; Paul A Overbeek
The retinoblastoma protein-binding region of simian virus 40 large T antigen alters cell cycle regulation in lenses of transgenic mice.
Molecular and cellular biology 1994;14(10):6743-54.
1994: Gregory I Liou; Suraporn Matragoon; Paul A Overbeek; You-Jun Fei
Identification of a retina-specific footprint within the retina-specific regulatory region of the human interphotoreceptor retinoid-binding protein gene.
Biochemical and biophysical research communications 1994;203(3):1875-81.
1994: Lonnie D Russell; L Ying; Paul A Overbeek
Insertional mutation that causes acrosomal hypo-development: its relationship to sperm head shaping.
The Anatomical record 1994;238(4):437-53.
1994: J H Winston; L Hong; S Akroyd; G Hanten; K Waymire; Paul A Overbeek; Rodney E Kellems
Diverse genetic regulatory elements are required to direct the proper tissue-specific and developmental expression of the murine adenosine deaminase gene.
Advances in experimental medicine and biology 1994;370():579-84.
1993: Patricia Chévez-Barrios; D L Schaffner; Roberto Barrios; Paul A Overbeek; RM Lebovitz; Michael W Lieberman
Expression of the rasT24 oncogene in the ciliary body pigment epithelium and retinal pigment epithelium results in hyperplasia, adenoma, and adenocarcinoma.
The American journal of pathology 1993;143(1):20-8.
1993: D L Schaffner; Roberto Barrios; C Massey; E I Bañez; Ching-Nan Ou; S Rajagopalan; Estuardo Aguilar-Cordova; RM Lebovitz; Paul A Overbeek; Michael W Lieberman
Targeting of the rasT24 oncogene to the proximal convoluted tubules in transgenic mice results in hyperplasia and polycystic kidneys.
The American journal of pathology 1993;142(4):1051-60.
1993: T Howard; R Balogh; Paul A Overbeek; Kenneth E Bernstein
Sperm-specific expression of angiotensin-converting enzyme (ACE) is mediated by a 91-base-pair promoter containing a CRE-like element.
Molecular and cellular biology 1993;13(1):18-27.
1992: Muayyad R Al-Ubaidi; Ramon L Font; Alexander B Quiambao; M J Keener; Gregory I Liou; Paul A Overbeek; Wolfgang Baehr
Bilateral retinal and brain tumors in transgenic mice expressing simian virus 40 large T antigen under control of the human interphotoreceptor retinoid-binding protein promoter.
The Journal of cell biology 1992;119(6):1681-7.
1992: T Yokoyama; Gregory I Liou; Ruth B Caldwell; Paul A Overbeek
Photoreceptor-specific activity of the human interphotoreceptor retinoid-binding protein (IRBP) promoter in transgenic mice.
Experimental eye research 1992;55(2):225-33.
1992: J H Winston; G R Hanten; Paul A Overbeek; Rodney E Kellems
5' flanking sequences of the murine adenosine deaminase gene direct expression of a reporter gene to specific prenatal and postnatal tissues in transgenic mice.
The Journal of biological chemistry 1992;267(19):13472-9.
1992: Muayyad R Al-Ubaidi; Joe G Hollyfield; Paul A Overbeek; Wolfgang Baehr
Photoreceptor degeneration induced by the expression of simian virus 40 large tumor antigen in the retina of transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1194-8.
1991: Paul A Overbeek; Estuardo Aguilar-Cordova; G Hanten; D L Schaffner; P Patel; RM Lebovitz; Michael W Lieberman
Coinjection strategy for visual identification of transgenic mice.
Transgenic research 1991;1(1):31-7.
1991: Gregory I Liou; Suraporn Matragoon; J Yang; L Geng; Paul A Overbeek; Din-Pow Ma
Retina-specific expression from the IRBP promoter in transgenic mice is conferred by 212 bp of the 5'-flanking region.
Biochemical and biophysical research communications 1991;181(1):159-65.
1991: G R MacGregor; Paul A Overbeek
Use of a simplified single-site PCR to facilitate cloning of genomic DNA sequences flanking a transgene integration site.
PCR methods and applications 1991;1(2):129-35.
1991: Lonnie D Russell; A P Hikim; Paul A Overbeek; G R MacGregor
Testis structure in the sys (symplastic spermatids) mouse.
The American journal of anatomy 1991;192(2):169-82.
1991: F A Fletcher; K A Moore; Malka Ashkenazi; P De Vries; Paul A Overbeek; D E Williams; John W Belmont
Leukemia inhibitory factor improves survival of retroviral vector-infected hematopoietic stem cells in vitro, allowing efficient long-term expression of vector-encoded human adenosine deaminase in vivo.
The Journal of experimental medicine 1991;174(4):837-45.
1991: K G Langford; S Y Shai; Tom E Howard; M J Kovac; Paul A Overbeek; Kenneth E Bernstein
Transgenic mice demonstrate a testis-specific promoter for angiotensin-converting enzyme.
The Journal of biological chemistry 1991;266(24):15559-62.
1990: T Yokoyama; D W Silversides; K G Waymire; B S Kwon; T Takeuchi; Paul A Overbeek
Conserved cysteine to serine mutation in tyrosinase is responsible for the classical albino mutation in laboratory mice.
Nucleic acids research 1990;18(24):7293-8.
1990: G R MacGregor; L D Russell; M E Van Beek; G R Hanten; M J Kovac; C A Kozak; M L Meistrich; Paul A Overbeek
Symplastic spermatids (sys): a recessive insertional mutation in mice causing a defect in spermatogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(13):5016-20.
1990: Gregory I Liou; L Geng; Muayyad R Al-Ubaidi; Suraporn Matragoon; G Hanten; Wolfgang Baehr; Paul A Overbeek
Tissue-specific expression in transgenic mice directed by the 5'-flanking sequences of the human gene encoding interphotoreceptor retinoid-binding protein.
The Journal of biological chemistry 1990;265(15):8373-6.
1989: W Shawlot; M J Siciliano; R L Stallings; Paul A Overbeek
Insertional inactivation of the downless gene in a family of transgenic mice.
Molecular biology & medicine 1989;6(4):299-307.