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Lut Overbergh

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Michael Maris; Chantal Mathieu; Sofie Robert; Etienne Waelkens; Miriam Cnop; Rita Derua; Wannes D'Hertog; Miriam H Hernangomez; Lut Overbergh
Role of the saturated nonesterified fatty acid palmitate in beta cell dysfunction.
Jessica L Dunne; Lut Overbergh; Anthony W Purcell; Chantal Mathieu
Posttranslational modifications of proteins in type 1 diabetes: the next step in finding the cure?
Gabriela Bomfim Ferreira; Daniel Aaen Hansen; Fleur S Kleijwegt; Kasper Lage; Tatjana Nikolic; Lut Overbergh; Bart O Roep; Etienne Waelkens; Christopher T Workman; Chantal Mathieu
Differential protein pathways in 1,25-dihydroxyvitamin d(3) and dexamethasone modulated tolerogenic human dendritic cells.

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All Publications

2013: Michael Maris; Chantal Mathieu; Sofie Robert; Etienne Waelkens; Miriam Cnop; Rita Derua; Wannes D'Hertog; Miriam H Hernangomez; Lut Overbergh
Role of the saturated nonesterified fatty acid palmitate in beta cell dysfunction.
Journal of proteome research 2013;12(1):347-62.
2012: Jessica L Dunne; Lut Overbergh; Anthony W Purcell; Chantal Mathieu
Posttranslational modifications of proteins in type 1 diabetes: the next step in finding the cure?
Diabetes 2012;61(8):1907-14.
2012: Gabriela Bomfim Ferreira; Daniel Aaen Hansen; Fleur S Kleijwegt; Kasper Lage; Tatjana Nikolic; Lut Overbergh; Bart O Roep; Etienne Waelkens; Christopher T Workman; Chantal Mathieu
Differential protein pathways in 1,25-dihydroxyvitamin d(3) and dexamethasone modulated tolerogenic human dendritic cells.
Journal of proteome research 2012;11(2):941-71.
2012: Liesbeth Viaene; Pieter Evenepoel; Björn Meijers; Lut Overbergh; Dirk Vanderschueren; Chantal Mathieu
Uremia suppresses immune signal-induced CYP27B1 expression in human monocytes.
American journal of nephrology 2012;36(6):497-508.
2012: Hamid Kermani; Frédéric Baron; Yves Beguin; Gwenaelle Bodart; Olivier Dardenne; Vincent Geenen; Lindsay Goffinet; Gabriel Morrhaye; Marie Mottet; Lut Overbergh; Chantal Renard; Henri J Martens
Expression of the growth hormone/insulin-like growth factor axis during Balb/c thymus ontogeny and effects of growth hormone upon ex vivo T cell differentiation.
Neuroimmunomodulation 2012;19(3):137-47.
2011: Heidi Wolden-Kirk; Lut Overbergh; Klaus Brusgaard; Henrik Thybo Christesen; Chantal Mathieu
Vitamin D and diabetes: its importance for beta cell and immune function.
Molecular and cellular endocrinology 2011;347(1-2):106-20.
2011: Gabriela Bomfim Ferreira; Conny Gysemans; Lut Overbergh; Evelyne van Etten; Annemieke Verstuyf; Mark Waer; Chantal Mathieu
1,25-Dihydroxyvitamin D3 alters murine dendritic cell behaviour in vitro and in vivo.
Diabetes/metabolism research and reviews 2011;27(8):933-41.
2011: Amelie Fassbender; Mutinda C. Kyama; Chantal Mathieu; Christel Meuleman; Lut Overbergh; Karen Peeraer; Carla Tomassetti; Eefje Verdrengh; Alexandra Vodolazakaia; Etienne Waelkens; Attila Bokor; Thomas M D'Hooghe
How can macroscopically normal peritoneum contribute to the pathogenesis of endometriosis?
Fertility and sterility 2011;96(3):697-9.
2011: Michael Maris; Lut Overbergh; Etienne Waelkens; Miriam Cnop; Daniel A Cunha; Wannes D'Hertog; Tatsuro Koike; Hannelie Korf; Chantal Mathieu
Oleate-induced beta cell dysfunction and apoptosis: a proteomic approach to glucolipotoxicity by an unsaturated fatty acid.
Journal of proteome research 2011;10(8):3372-85.
2011: Michela Di Michele; Chantal Thys; Etienne Waelkens; Lut Overbergh; Wannes D'Hertog; Chantal Mathieu; Rita De Vos; Kathelijne Peerlinck; Chris Van Geet; Kathleen Freson
An integrated proteomics and genomics analysis to unravel a heterogeneous platelet secretion defect.
Journal of proteomics 2011;74(6):902-13.
2011: Wannes D'Hertog; Michael Maris; Lieven Thorrez; Etienne Waelkens; Lut Overbergh; Chantal Mathieu
Two-dimensional gel proteome reference map of INS-1E cells.
Proteomics 2011;11(7):1365-9.
2011: Isabelle Clinckspoor; Lieve Verlinden; Lut Overbergh; Christopher Korch; Roger Bouillon; Chantal Mathieu; Annemieke Verstuyf; Brigitte Decallonne
1,25-dihydroxyvitamin D3 and a superagonistic analog in combination with paclitaxel or suberoylanilide hydroxamic acid have potent antiproliferative effects on anaplastic thyroid cancer.
The Journal of steroid biochemistry and molecular biology 2011;124(1-2):1-9.
2011: Femke Baeke; Hannelie Korf; Lut Overbergh; Annemieke Verstuyf; Lieven Thorrez; Leentje Van Lommel; Mark Waer; Frans Schuit; Conny Gysemans; Chantal Mathieu
The vitamin D analog, TX527, promotes a human CD4+CD25highCD127low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(1):132-42.
2010: Michael Maris; Gabriela B Ferreira; Wannes D'Hertog; Miriam Cnop; Etienne Waelkens; Lut Overbergh; Chantal Mathieu
High glucose induces dysfunction in insulin secretory cells by different pathways: a proteomic approach.
Journal of proteome research 2010;9(12):6274-87.
2010: Wannes D'Hertog; Michael Maris; Gabriela B Ferreira; Eefje Verdrengh; Kasper Lage; Daniel A Hansen; Alessandra K Cardozo; Christopher T Workman; Yves Moreau; Decio L Eizirik; Etienne Waelkens; Lut Overbergh; Chantal Mathieu
Novel insights into the global proteome responses of insulin-producing INS-1E cells to different degrees of endoplasmic reticulum stress.
Journal of proteome research 2010;9(10):5142-52.
2010: L Noé; M Di Michele; E Giets; Chantal Thys; Christine Wittevrongel; Rita De Vos; Lut Overbergh; E Waelkens; Jaak Jaeken; C Van Geet; Kathleen Freson
Platelet Gs hypofunction and abnormal morphology resulting from a heterozygous RGS2 mutation.
Journal of thrombosis and haemostasis : JTH 2010;8(7):1594-603.
2010: Femke Baeke; Hannelie Korf; Lut Overbergh; Evelyne van Etten; Annemieke Verstuyf; Conny Gysemans; Chantal Mathieu
Human T lymphocytes are direct targets of 1,25-dihydroxyvitamin D3 in the immune system.
The Journal of steroid biochemistry and molecular biology 2010;121(1-2):221-7.
2010: Lin X Chen; Shao-xia Lin; Sanober Amin; Lut Overbergh; Giacomo Maggiolino; Lawrence S Chan
VCAM-1 blockade delays disease onset, reduces disease severity and inflammatory cells in an atopic dermatitis model.
Immunology and cell biology 2010;88(3):334-42.
2010: Gabriela Bomfim Ferreira; Chantal Mathieu; Lut Overbergh
Understanding dendritic cell biology and its role in immunological disorders through proteomic profiling.
Proteomics. Clinical applications 2010;4(2):190-203.
2009: Gabriela Bomfim Ferreira; Evelyne van Etten; Kasper Lage; Daniel Aaen Hansen; Yves Moreau; Christopher T Workman; Mark Waer; Annemieke Verstuyf; Etienne Waelkens; Lut Overbergh; Chantal Mathieu
Proteome analysis demonstrates profound alterations in human dendritic cell nature by TX527, an analogue of vitamin D.
Proteomics 2009;9(14):3752-64.
2008: Femke Baeke; Evelyne van Etten; Conny Gysemans; Lut Overbergh; Chantal Mathieu
Vitamin D signaling in immune-mediated disorders: Evolving insights and therapeutic opportunities.
Molecular aspects of medicine 2008;29(6):376-87.
2008: Evelyne van Etten; Katinka Stoffels; Conny Gysemans; Chantal Mathieu; Lut Overbergh
Regulation of vitamin D homeostasis: implications for the immune system.
Nutrition reviews 2008;66(10 Suppl 2):S125-34.
2008: Gabriela Bomfim Ferreira; Lut Overbergh; Evelyne van Etten; Kasper Lage; Wannes D'Hertog; Daniel Aaen Hansen; Michael Maris; Yves Moreau; Christopher T Workman; Etienne Waelkens; Chantal Mathieu
Protein-induced changes during the maturation process of human dendritic cells: A 2-D DIGE approach.
Proteomics. Clinical applications 2008;2(9):1349-60.
2008: Isabelle Meyts; Jeroen A J Vanoirbeek; Greet Hens; Bart M Vanaudenaerde; Bert Verbinnen; dominique ma bullens; Lut Overbergh; Chantal Mathieu; Jan L Ceuppens; Peter W Hellings
T-cell mediated late increase in bronchial tone after allergen provocation in a murine asthma model.
Clinical immunology (Orlando, Fla.) 2008;128(2):248-58.
2008: Lin X Chen; Lut Overbergh; C Mathieu; Lawrence S Chan
The development of atopic dermatitis is independent of Immunoglobulin E up-regulation in the K14-IL-4 SKH1 transgenic mouse model.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008;38(8):1367-80.
2008: Conny Gysemans; Hanne Callewaert; Lut Overbergh; Chantal Mathieu
Cytokine signalling in the beta-cell: a dual role for IFNgamma.
Biochemical Society transactions 2008;36(Pt 3):328-33.
2008: Mutinda C. Kyama; Lut Overbergh; Attila Mihalyi; Silvio Cuneo; Daniel Chivatsi Chai; Sophie Debrock; Jason M Mwenda; Chantal Mathieu; Noreen P Nugent; Thomas M D'Hooghe
Effect of recombinant human TNF-binding protein-1 and GnRH antagonist on mRNA expression of inflammatory cytokines and adhesion and growth factors in endometrium and endometriosis tissues in baboons.
Fertility and sterility 2008;89(5 Suppl):1306-13.
2008: Michael Maris; Wannes D'Hertog; Lut Overbergh; Chantal Mathieu
Proteomics as a tool to discover biomarkers for the prediction of diabetic complications.
Expert opinion on medical diagnostics 2008;2(3):277-87.
2008: Michael Maris; Lut Overbergh; Chantal Mathieu
Type 2 diabetes: Gaining insight into the disease process using proteomics.
Proteomics. Clinical applications 2008;2(3):312-26.
2008: Mutinda C. Kyama; Lut Overbergh; Attila Mihalyi; Christel Meuleman; Jason M Mwenda; Chantal Mathieu; Thomas M D'Hooghe
Endometrial and peritoneal expression of aromatase, cytokines, and adhesion factors in women with endometriosis.
Fertility and sterility 2008;89(2):301-10.
2008: Conny Gysemans; Evelyne van Etten; Lut Overbergh; Annapaula Giulietti; Guy Eelen; Mark Waer; Annemieke Verstuyf; Roger Bouillon; Chantal Mathieu
Unaltered diabetes presentation in NOD mice lacking the vitamin D receptor.
Diabetes 2008;57(1):269-75.
2007: Wannes D'Hertog; Lut Overbergh; Kasper Lage; Gabriela Bonfim Ferreira; Michael Maris; Conny Gysemans; Daisy Flamez; Alessandra Kupper Cardozo; Gert Van den Bergh; Liliane Schoofs; Lutgarde Arckens; Yves Moreau; Daniel Aaen Hansen; Decio L Eizirik; Ettienne Waelkens; Chantal Mathieu
Proteomics analysis of cytokine-induced dysfunction and death in insulin-producing INS-1E cells: new insights into the pathways involved.
Molecular & cellular proteomics : MCP 2007;6(12):2180-99.
2007: Hanne Callewaert; Conny Gysemans; Laurence Ladrière; Wannes D'Hertog; Julianna Hagenbrock; Lut Overbergh; Decio L Eizirik; Chantal Mathieu
Deletion of STAT-1 pancreatic islets protects against streptozotocin-induced diabetes and early graft failure but not against late rejection.
Diabetes 2007;56(8):2169-73.
2007: Annapaula Giulietti; Evelyne van Etten; Lut Overbergh; Katinka Stoffels; Roger Bouillon; Chantal Mathieu
Monocytes from type 2 diabetic patients have a pro-inflammatory profile. 1,25-Dihydroxyvitamin D(3) works as anti-inflammatory.
Diabetes research and clinical practice 2007;77(1):47-57.
2007: Kurt Boonen; Geert Baggerman; Wannes D'Hertog; Steven J Husson; Lut Overbergh; Chantal Mathieu; Liliane Schoofs
Neuropeptides of the islets of Langerhans: a peptidomics study.
General and comparative endocrinology 2007;152(2-3):231-41.
2007: Katinka Stoffels; Lut Overbergh; Roger Bouillon; Chantal Mathieu
Immune regulation of 1alpha-hydroxylase in murine peritoneal macrophages: unravelling the IFNgamma pathway.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):567-71.
2007: Evelyne van Etten; Conny Gysemans; Dumitru D Branisteanu; Annemieke Verstuyf; Roger Bouillon; Lut Overbergh; Chantal Mathieu
Novel insights in the immune function of the vitamin D system: synergism with interferon-beta.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):546-51.
2007: Evelyne van Etten; Lieve Verlinden; Annapaula Giulietti; Elizabeth Ramos Lopez; Dumitru D Branisteanu; Gabriela B Ferreira; Lut Overbergh; Annemieke Verstuyf; Roger Bouillon; Bart O Roep; Klaus Badenhoop; Chantal Mathieu
The vitamin D receptor gene FokI polymorphism: functional impact on the immune system.
European journal of immunology 2007;37(2):395-405.
2006: Isabelle Meyts; Peter W Hellings; Greet Hens; Bart M Vanaudenaerde; Bert Verbinnen; Hubertine Heremans; Patrick Matthys; dominique ma bullens; Lut Overbergh; Chantal Mathieu; Kris De Boeck; Jan L Ceuppens
IL-12 contributes to allergen-induced airway inflammation in experimental asthma.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(9):6460-70.
2006: Peter W Hellings; Ahmad Kasran; dominique ma bullens; Lut Overbergh; Chantal Mathieu; Hubertine Heremans; Patrick Matthys; Louis Boon; Mark Jorissen; Jan L Ceuppens
IL-10- and IL-12-independent down-regulation of allergic sensitization by stimulation of CD40 signaling.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(8):5138-44.
2006: Lut Overbergh; Katinka Stoffels; Mark Waer; Annemieke Verstuyf; Roger Bouillon; Chantal Mathieu
Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction.
The Journal of clinical endocrinology and metabolism 2006;91(9):3566-74.
2006: Katleen Vantieghem; Lut Overbergh; Geert Carmeliet; Petra De Haes; Roger Bouillon; Siegfried Segaert
UVB-induced 1,25(OH)2D3 production and vitamin D activity in intestinal CaCo-2 cells and in THP-1 macrophages pretreated with a sterol Delta7-reductase inhibitor.
Journal of cellular biochemistry 2006;99(1):229-40.
2006: Lin X Chen; Shao-xia Lin; Rania Agha-Majzoub; Lut Overbergh; Chantal Mathieu; Lawrence S Chan
CCL27 is a critical factor for the development of atopic dermatitis in the keratin-14 IL-4 transgenic mouse model.
International immunology 2006;18(8):1233-42.
2006: Mutinda C. Kyama; Lut Overbergh; Sophie Debrock; Dirk Valckx; Sarah Vander Perre; Christel Meuleman; Attila Mihalyi; Jason M Mwenda; Chantal Mathieu; Thomas M D'Hooghe
Increased peritoneal and endometrial gene expression of biologically relevant cytokines and growth factors during the menstrual phase in women with endometriosis.
Fertility and sterility 2006;85(6):1667-75.
2006: Wannes D'Hertog; Chantal Mathieu; Lut Overbergh
Type 1 diabetes: entering the proteomic era.
Expert review of proteomics 2006;3(2):223-36.
2006: Marie-Claire Toufektsian; Zequan Yang; Prasad Konkalmatt; Lut Overbergh; Susan I Ramos; Chantal Mathieu; Joel Linden; Brent A French
Stimulation of A2A-adenosine receptors after myocardial infarction suppresses inflammatory activation and attenuates contractile dysfunction in the remote left ventricle.
American journal of physiology. Heart and circulatory physiology 2006;290(4):H1410-8.
2006: Philippe Maerten; B S Kwon; Chong Shen; Gert De Hertogh; Pascal Cadot; dominique ma bullens; Lut Overbergh; Chantal Mathieu; Gert van Assche; Karel Geboes; Paul Rutgeerts; Jan L Ceuppens
Involvement of 4-1BB (CD137)-4-1BBligand interaction in the modulation of CD4 T cell-mediated inflammatory colitis.
Clinical and experimental immunology 2006;143(2):228-36.
2006: Lut Overbergh; Conny Gysemans; Chantal Mathieu
Quantification of chemokines by real-time reverse transcriptase PCR: applications in type 1 diabetes.
Expert review of molecular diagnostics 2006;6(1):51-64.
2006: Katinka Stoffels; Lut Overbergh; Annapaula Giulietti; Lieve Verlinden; Roger Bouillon; Chantal Mathieu
Immune regulation of 25-hydroxyvitamin-D3-1alpha-hydroxylase in human monocytes.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(1):37-47.
2005: Michaël Boudewijns; Axel Jeurissen; Margaretha Wuyts; Leen Moens; Louis Boon; Joost J Van Neerven; Ahmad Kasran; Lut Overbergh; Caroline Lenaerts; Marc Waer; Chantal Mathieu; Jan L Ceuppens; Xavier Bossuyt
Blockade of CTLA-4 (CD152) enhances the murine antibody response to pneumococcal capsular polysaccharides.
Journal of leukocyte biology 2005;78(5):1060-9.
2005: Lin X Chen; Shao-xia Lin; Lut Overbergh; Chantal Mathieu; Lawrence S Chan
The disease progression in the keratin 14 IL-4-transgenic mouse model of atopic dermatitis parallels the up-regulation of B cell activation molecules, proliferation and surface and serum IgE.
Clinical and experimental immunology 2005;142(1):21-30.
2005: Lut Overbergh; Mutinda C. Kyama; Dirk Valckx; Sophie Debrock; Jason M Mwenda; Chantal Mathieu; Thomas M D'Hooghe
Validation of real-time RT-PCR assays for mRNA quantification in baboons.
Cytokine 2005;31(6):454-8.
2005: Brigitte Decallonne; Evelyne van Etten; Lut Overbergh; Dirk Valckx; Roger Bouillon; Chantal Mathieu
1Alpha,25-dihydroxyvitamin D3 restores thymocyte apoptosis sensitivity in non-obese diabetic (NOD) mice through dendritic cells.
Journal of autoimmunity 2005;24(4):281-9.
2005: Axel Jeurissen; Evelyne van Etten; Lut Overbergh; Greet Wuyts; Hubertine Heremans; Patrick Matthys; Jan L Ceuppens; Chantal Mathieu; Xavier Bossuyt
1alpha,25-Dihydroxyvitamin D3 modulates the murine antibody response to pneumococcal capsular polysaccharide serotype 3 through IL-12.
European journal of immunology 2005;35(6):1841-8.
2004: Hiroaki Kitade; Masaru Kawai; Takaaki Koshiba; Annapaula Giulietti; Lut Overbergh; Omer Rutgeerts; Dirk Valckx; Mark Waer; Chantal Mathieu; Jacques Pirenne
Early accumulation of interferon-gamma in grafts tolerized by donor-specific blood transfusion: friend or enemy?
Transplantation 2004;78(12):1747-55.
2004: Evelyne van Etten; Olivier Dardenne; Conny Gysemans; Lut Overbergh; Chantal Mathieu
1,25-Dihydroxyvitamin D3 alters the profile of bone marrow-derived dendritic cells of NOD mice.
Annals of the New York Academy of Sciences 2004;1037():186-92.
2004: Annapaula Giulietti; Katinka Stoffels; Brigitte Decallonne; Lut Overbergh; Chantal Mathieu
Monocytic expression behavior of cytokines in diabetic patients upon inflammatory stimulation.
Annals of the New York Academy of Sciences 2004;1037():74-8.
2004: Lin X Chen; O Martinez; Lut Overbergh; Chantal Mathieu; Bellur S Prabhakar; Lawrence S Chan
Early up-regulation of Th2 cytokines and late surge of Th1 cytokines in an atopic dermatitis model.
Clinical and experimental immunology 2004;138(3):375-87.
2004: Katinka Stoffels; Lut Overbergh; Annapaula Giulietti; Ahmad Kasran; Roger Bouillon; Conny Gysemans; Chantal Mathieu
NOD macrophages produce high levels of inflammatory cytokines upon encounter of apoptotic or necrotic cells.
Journal of autoimmunity 2004;23(1):9-15.
2004: Lut Overbergh; Katinka Stoffels; Dirk Valckx; Annapaula Giulietti; Roger Bouillon; Chantal Mathieu
Regulation of 25-hydroxyvitamin d-1alpha-hydroxylase by IFNgamma in human monocytic THP1 cells.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):453-5.
2004: Chantal Mathieu; Evelyne van Etten; Brigitte Decallonne; Annapaula Guilietti; Conny Gysemans; Roger Bouillon; Lut Overbergh
Vitamin D and 1,25-dihydroxyvitamin D3 as modulators in the immune system.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):449-52.
2004: Annapaula Giulietti; Conny Gysemans; Katinka Stoffels; Evelyne van Etten; Brigitte Decallonne; Lut Overbergh; Roger Bouillon; Chantal Mathieu
Vitamin D deficiency in early life accelerates Type 1 diabetes in non-obese diabetic mice.
Diabetologia 2004;47(3):451-62.
2003: Dumitru D Branisteanu; Lut Overbergh; Brigitte Decallonne; Chantal Mathieu
Hen egg white lysozyme vaccination induces acute shock in NOD mice.
Annals of the New York Academy of Sciences 2003;1005():215-7.
2003: Takaaki Koshiba; Hiroaki Kitade; Boudewijn Van Damme; Annapaula Giulietti; Lut Overbergh; Chantal Mathieu; Mark Waer; Jacques Pirenne
Regulatory cell-mediated tolerance does not protect against chronic rejection.
Transplantation 2003;76(3):588-96.
2003: Conny Gysemans; Katinka Stoffels; Annapaula Giulietti; Lut Overbergh; Mark Waer; M Lannoo; Ulrich Feige; Chantal Mathieu
Prevention of primary non-function of islet xenografts in autoimmune diabetic NOD mice by anti-inflammatory agents.
Diabetologia 2003;46(8):1115-23.
2003: Brigitte Decallonne; Evelyne van Etten; Annapaula Giulietti; Kristina Casteels; Lut Overbergh; Roger Bouillon; Chantal Mathieu
Defect in activation-induced cell death in non-obese diabetic (NOD) T lymphocytes.
Journal of autoimmunity 2003;20(3):219-26.
2003: Evelyne van Etten; Dumitru D Branisteanu; Lut Overbergh; Roger Bouillon; Annemieke Verstuyf; Chantal Mathieu
Combination of a 1,25-dihydroxyvitamin D3 analog and a bisphosphonate prevents experimental autoimmune encephalomyelitis and preserves bone.
Bone 2003;32(4):397-404.
2003: Lut Overbergh; Annapaula Giulietti; Dirk Valckx; R Decallonne; Roger Bouillon; Chantal Mathieu
The use of real-time reverse transcriptase PCR for the quantification of cytokine gene expression.
Journal of biomolecular techniques : JBT 2003;14(1):33-43.
2003: Takaaki Koshiba; Annapaula Giulietti; Boudewijn Van Damme; Lut Overbergh; Omer Rutgeerts; Hiroaki Kitade; Mark Waer; Chantal Mathieu; Jacques Pirenne
Paradoxical early upregulation of intragraft Th1 cytokines is associated with graft acceptance following donor-specific blood transfusion.
Transplant international : official journal of the European Society for Organ Transplantation 2003;16(3):179-85.
2003: Lut Overbergh; Brigitte Decallonne; Dumitru D Branisteanu; Dirk Valckx; Ahmad Kasran; Roger Bouillon; Chantal Mathieu
Acute shock induced by antigen vaccination in NOD mice.
Diabetes 2003;52(2):335-41.
2003: Peter W Hellings; Ahmad Kasran; Zhanju Liu; Philippe Vandekerckhove; Anja Wuyts; Lut Overbergh; Chantal Mathieu; Jan L Ceuppens
Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma.
American journal of respiratory cell and molecular biology 2003;28(1):42-50.
2002: T Koshiba; Boudewijn Van Damme; Y Lu; Y Yan; Omer Rutgeerts; Lut Overbergh; K Tanaka; M Waer; C Mathieu; J Pirenne
Combined use of FTY720 and cyclosporine A prevents chronic allograft vasculopathy.
Transplantation proceedings 2002;34(3):748-9.
2002: Conny Gysemans; Evelyne van Etten; Lut Overbergh; Annemieke Verstuyf; Mark Waer; Roger Bouillon; Chantal Mathieu
Treatment of autoimmune diabetes recurrence in non-obese diabetic mice by mouse interferon-beta in combination with an analogue of 1alpha,25-dihydroxyvitamin-D3.
Clinical and experimental immunology 2002;128(2):213-20.
2002: Peter W Hellings; Peter Vandenberghe; Ahmad Kasran; Lieve Coorevits; Lut Overbergh; Chantal Mathieu; Jan L Ceuppens
Blockade of CTLA-4 enhances allergic sensitization and eosinophilic airway inflammation in genetically predisposed mice.
European journal of immunology 2002;32(2):585-94.
2001: Annapaula Giulietti; Lut Overbergh; Dirk Valckx; Brigitte Decallonne; Roger Bouillon; Chantal Mathieu
An overview of real-time quantitative PCR: applications to quantify cytokine gene expression.
Methods (San Diego, Calif.) 2001;25(4):386-401.
2001: Zhanju Liu; Karel Geboes; Hubertine Heremans; Lut Overbergh; Chantal Mathieu; Paul Rutgeerts; Jan L Ceuppens
Role of interleukin-12 in the induction of mucosal inflammation and abrogation of regulatory T cell function in chronic experimental colitis.
European journal of immunology 2001;31(5):1550-60.
2001: Takaaki Koshiba; Boudewijn Van Damme; Ping Ji; Y Lu; Yehong Yan; Hassan Sefrioui; Omer Rutgeerts; Lut Overbergh; K Tanaka; Chantal Mathieu; Mark Waer; Jacques Pirenne
Intestinal allografts delay rejection and prolong survival of combined donor-specific and third party solid organ transplants.
Transplantation proceedings 2001;33(1-2):1550-2.
2001: Takaaki Koshiba; Boudewijn Van Damme; Ping Ji; Y Lu; Hassan Sefrioui; Lut Overbergh; K Tanaka; Chantal Mathieu; Mark Waer; Jacques Pirenne
Addition of steroids blocks the tolerogenic potential of donor-specific blood transfusion.
Transplantation proceedings 2001;33(1-2):375-6.
2001: An D Billiau; Hassan Sefrioui; Lut Overbergh; Omer Rutgeerts; Jozef Goebels; Mark Waer
The graft-versus-leukemia effect in allogeneic irradiation bone marrow chimeras: possible suppressive role of irradiation-induced TGF-beta.
Transplantation proceedings 2001;33(1-2):336-7.
2001: An D Billiau; Hassan Sefrioui; Lut Overbergh; Omer Rutgeerts; Jozef Goebels; Chantal Mathieu; Mark Waer
Transforming growth factor-beta inhibits lymphokine activated killer cytotoxicity of bone marrow cells: implications for the graft-versus-leukemia effect in irradiation allogeneic bone marrow chimeras.
Transplantation 2001;71(2):292-9.
2000: Brigitte Decallonne; Lut Overbergh; Kristina Casteels; Conny Gysemans; Roger Bouillon; Chantal Mathieu
Streptococcal wall component OK432 restores sensitivity of non-obese diabetic (NOD) thymocytes to apoptotic signals.
Diabetologia 2000;43(10):1302-8.
2000: Lut Overbergh; Brigitte Decallonne; Mark Waer; Omer Rutgeerts; Dirk Valckx; Kristina Casteels; JM Laureys; Roger Bouillon; Chantal Mathieu
1alpha,25-dihydroxyvitamin D3 induces an autoantigen-specific T-helper 1/T-helper 2 immune shift in NOD mice immunized with GAD65 (p524-543).
Diabetes 2000;49(8):1301-7.
2000: Zhanju Liu; Karel Geboes; Stefaan Colpaert; Lut Overbergh; Chantal Mathieu; Hubertine Heremans; M de Boer; Louis Boon; GR D'Haens; Paul Rutgeerts; Jan L Ceuppens
Prevention of experimental colitis in SCID mice reconstituted with CD45RBhigh CD4+ T cells by blocking the CD40-CD154 interactions.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(11):6005-14.
2000: Lut Overbergh; Brigitte Decallonne; Dirk Valckx; Annemieke Verstuyf; J Depovere; JM Laureys; Omer Rutgeerts; R Saint-Arnaud; Roger Bouillon; Chantal Mathieu
Identification and immune regulation of 25-hydroxyvitamin D-1-alpha-hydroxylase in murine macrophages.
Clinical and experimental immunology 2000;120(1):139-46.
1999: Hassan Sefrioui; An D Billiau; Lut Overbergh; Omer Rutgeerts; Mark Waer
Influence of the additional injection of host-type bone marrow on the immune tolerance of minor antigen-mismatched chimeras: possible involvement of double-negative (natural killer) T cells.
Transplantation 1999;68(10):1560-7.
1999: LM Kuschnaroff; Lut Overbergh; H Sefriouni; H Sobis; Michel Vandeputte; Mark Waer
Effect of staphylococcal enterotoxin B injection on the development of experimental autoimmune encephalomyelitis: influence of cytokine and inducible nitric oxide synthase production.
Journal of neuroimmunology 1999;99(2):157-68.
1999: Lut Overbergh; Dirk Valckx; Mark Waer; Chantal Mathieu
Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR.
Cytokine 1999;11(4):305-12.
1999: Hassan Sefrioui; An D Billiau; Lut Overbergh; Omer Rutgeerts; Mark Waer
Tolerance in Mlsa mismatched chimeras prepared with allogeneic bone marrow alone or in combination with syngeneic bone marrow.
Transplantation proceedings 1999;31(1-2):702-3.
1998: Kristina Casteels; Chantal Mathieu; Mark Waer; Dirk Valckx; Lut Overbergh; JM Laureys; Roger Bouillon
Prevention of type I diabetes in nonobese diabetic mice by late intervention with nonhypercalcemic analogs of 1,25-dihydroxyvitamin D3 in combination with a short induction course of cyclosporin A.
Endocrinology 1998;139(1):95-102.
1995: Lieve Umans; Lutgarde Serneels; Lut Overbergh; K Lorent; Fred Van Leuven; Herman Van Den Berghe
Targeted inactivation of the mouse alpha 2-macroglobulin gene.
The Journal of biological chemistry 1995;270(34):19778-85.
1995: Lut Overbergh; K Lorent; S Torrekens; Fred Van Leuven; H Van den Berghe
Expression of mouse alpha-macroglobulins, lipoprotein receptor-related protein, LDL receptor, apolipoprotein E, and lipoprotein lipase in pregnancy.
Journal of lipid research 1995;36(8):1774-86.
1995: K Lorent; Lut Overbergh; Dieder Moechars; Bart De Strooper; Fred Van Leuven; Herman Van Den Berghe
Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein lipase, alpha-2-macroglobulin and the 40,000 molecular weight receptor-associated protein.
Neuroscience 1995;65(4):1009-25.
1995: Fred Van Leuven; C Hilliker; Lutgarde Serneels; Lieve Umans; Lut Overbergh; Bart De Strooper; J P Fryns; Herman Van Den Berghe
Cloning, characterization, and chromosomal localization to 4p16 of the human gene (LRPAP1) coding for the alpha 2-macroglobulin receptor-associated protein and structural comparison with the murine gene coding for the 44-kDa heparin-binding protein.
Genomics 1995;25(2):492-500.
1994: Fred Van Leuven; L Stas; C Hilliker; K Lorent; Lieve Umans; Lutgarde Serneels; Lut Overbergh; S Torrekens; Dieder Moechars; Bart De Strooper
Structure of the gene (LRP1) coding for the human alpha 2-macroglobulin receptor lipoprotein receptor-related protein.
Genomics 1994;24(1):78-89.
1994: K Lorent; Lut Overbergh; Fred Van Leuven
Expression of mouse alpha 2M and its receptor in vivo.
Annals of the New York Academy of Sciences 1994;737():498-9.
1994: Lut Overbergh; K Lorent; C Hilliker; Fred Van Leuven
Characterization of the genes coding for the murinoglobulins and expression in vivo.
Annals of the New York Academy of Sciences 1994;737():496-7.
1994: Fred Van Leuven; Lieve Umans; K Lorent; C Hilliker; Lutgarde Serneels; Lut Overbergh; L Stas; L Raymakers
Molecular analysis of the human and mouse alpha 2M family.
Annals of the New York Academy of Sciences 1994;737():163-71.
1994: Lut Overbergh; C Hilliker; K Lorent; Fred Van Leuven; Herman Van Den Berghe
Identification of four genes coding for isoforms of murinoglobulin, the monomeric mouse alpha 2-macroglobulin: characterization of the exons coding for the bait region.
Genomics 1994;22(3):530-9.
1994: Lieve Umans; Lutgarde Serneels; C Hilliker; L Stas; Lut Overbergh; Bart De Strooper; Fred Van Leuven; Herman Van Den Berghe
Molecular cloning of the mouse gene coding for alpha 2-macroglobulin and targeting of the gene in embryonic stem cells.
Genomics 1994;22(3):519-29.
1994: K Lorent; Lut Overbergh; Jan Delabie; Fred Van Leuven; Herman Van Den Berghe
Distribution of mRNA coding for alpha-2-macroglobulin, the murinoglobulins, the alpha-2-macroglobulin receptor and the alpha-2-macroglobulin receptor associated protein during mouse embryogenesis and in adult tissues.
Differentiation; research in biological diversity 1994;55(3):213-23.
1993: Fred Van Leuven; L Stas; L Raymakers; Lut Overbergh; Bart De Strooper; C Hilliker; K Lorent; E Fias; Lieve Umans; S Torrekens
Molecular cloning and sequencing of the murine alpha-2-macroglobulin receptor cDNA.
Biochimica et biophysica acta 1993;1173(1):71-4.
1992: Fred Van Leuven; S Torrekens; Lut Overbergh; K Lorent; Bart De Strooper; Herman Van Den Berghe
The primary sequence and the subunit structure of mouse alpha-2-macroglobulin, deduced from protein sequencing of the isolated subunits and from molecular cloning of the cDNA.
European journal of biochemistry / FEBS 1992;210(1):319-27.
1992: C Hilliker; Lut Overbergh; P Petit; Fred Van Leuven; Herman Van Den Berghe
Assignment of mouse alpha-2-macroglobulin gene to chromosome 6 band F1-G3.
Mammalian genome : official journal of the International Mammalian Genome Society 1992;3(8):469-71.
1991: Lut Overbergh; S Torrekens; Fred Van Leuven; Herman Van Den Berghe
Molecular characterization of the murinoglobulins.
The Journal of biological chemistry 1991;266(25):16903-10.