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Larry Overman

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Phenomena

Genes & Molecular Sequences

Molecular Structure

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Procedures

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Strychnos

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Co-Publications
Name
8
Cohen, Frederick
7
Pennington, Lewis
5
Aron, Zachary
4
Douglas, Christopher
4
Dounay, Amy
4
Hiebert, Sheldon
4
MacMillan, DW
4
Kirsch, Stefan
4
Kodanko, Jeremy
3
Watson, Donald
3
Peterson, Emily
3
Collins, Shawn
2
Nilsson, Bradley
2
Lebsack, Alec
2
Velthuisen, Emile

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Publications

TOP 3
Corminboeuf Olivier; Overman Larry E; Pennington Lewis D
A unified strategy for enantioselective total synthesis of cladiellin and briarellin diterpenes: total synthesis of briarellins E and F and the putative structure of alcyonin and revision of its structure assignment.
Nilsson Bradley L; Overman Larry E; Read de Alaniz Javier; Rohde Jason M
Enantioselective total syntheses of nankakurines A and B: confirmation of structure and establishment of absolute configuration.
Overman Larry E; Roberts Scott W; Sneddon Helen F
Catalytic asymmetric synthesis of allylic thiol derivatives.

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All Publications

2009: Corminboeuf Olivier; Overman Larry E; Pennington Lewis D
A unified strategy for enantioselective total synthesis of cladiellin and briarellin diterpenes: total synthesis of briarellins E and F and the putative structure of alcyonin and revision of its structure assignment.
The Journal of organic chemistry 2009;74(15):5458-70.
2008: Nilsson Bradley L; Overman Larry E; Read de Alaniz Javier; Rohde Jason M
Enantioselective total syntheses of nankakurines A and B: confirmation of structure and establishment of absolute configuration.
Journal of the American Chemical Society 2008;130(34):11297-9.
2008: Overman Larry E; Roberts Scott W; Sneddon Helen F
Catalytic asymmetric synthesis of allylic thiol derivatives.
Organic letters 2008;10(7):1485-8.
2008: Dounay Amy B; Humphreys Philip G; Overman Larry E; Wrobleski Aaron D
Total synthesis of the strychnos alkaloid (+)-minfiensine: tandem enantioselective intramolecular Heck-iminium ion cyclization.
Journal of the American Chemical Society 2008;130(15):5368-77.
2007: Overman Larry E; Sato Takaaki
Construction of epidithiodioxopiperazines by directed oxidation of hydroxyproline-derived dioxopiperazines.
Organic letters 2007;9(25):5267-70.
2007: Lanman Brian A; Overman Larry E; Paulini Ralph; White Nicole S
On the structure of palau'amine: evidence for the revised relative configuration from chemical synthesis.
Journal of the American Chemical Society 2007;129(42):12896-900.
2007: Kodanko Jeremy J; Hiebert Sheldon; Peterson Emily A; Sung Leonard; Overman Larry E; de Moura Linck Viviane; Goerck Greice Catrine; Amador Tânia Alves; Leal Mirna Bainy; Elisabetsky Elaine
Synthesis of all low-energy stereoisomers of the tris(pyrrolidinoindoline) alkaloid hodgkinsine and preliminary assessment of their antinociceptive activity.
The Journal of organic chemistry 2007;72(21):7909-14.
2007: Becker Michael H; Chua Peter; Downham Robert; Douglas Christopher J; Garg Neil K; Hiebert Sheldon; Jaroch Stefan; Matsuoka Richard T; Middleton Joy A; Ng Fay W; Overman Larry E
Total synthesis of (-)-sarain A.
Journal of the American Chemical Society 2007;129(39):11987-2002.
2007: Watson Mary P; Overman Larry E; Bergman Robert G
Kinetic and computational analysis of the palladium(II)-catalyzed asymmetric allylic trichloroacetimidate rearrangement: development of a model for enantioselectivity.
Journal of the American Chemical Society 2007;129(16):5031-44.
2007: Kirsch Stefan F; Overman Larry E; White Nicole S
Catalytic asymmetric synthesis of allylic aryl ethers.
Organic letters 2007;9(5):911-3.
2007: Overman Larry E; Shin Youseung
Enantioselective total synthesis of (+)-gliocladin C.
Organic letters 2007;9(2):339-41.
2006: Gergely Joshua; Morgan Jeremy B; Overman Larry E
Stereocontrolled synthesis of functionalized cis-cyclopentapyrazolidines by 1,3-dipolar cycloaddition reactions of azomethine imines.
The Journal of organic chemistry 2006;71(24):9144-52.
2006: Iimura Shin; Overman Larry E; Paulini Ralph; Zakarian Armen
Enantioselective total synthesis of guanacastepene N using an uncommon 7-endo Heck cyclization as a pivotal step.
Journal of the American Chemical Society 2006;128(40):13095-101.
2006: Nilsson Bradley L; Overman Larry E
Concise synthesis of guanidine-containing heterocycles using the Biginelli reaction.
The Journal of organic chemistry 2006;71(20):7706-14.
2006: Garg Neil K; Hiebert Sheldon; Overman Larry E
Total synthesis of (-)-sarain A.
Angewandte Chemie (International ed. in English) 2006;45(18):2912-5.
2006: Overman Larry E; Watson Donald A
Diastereoselection in the formation of contiguous quaternary carbon stereocenters by the intramolecular Heck reaction.
The Journal of organic chemistry 2006;71(7):2600-8.
2006: Overman Larry E; Watson Donald A
Diastereoselection in the formation of spirocyclic oxindoles by the intramolecular Heck reaction.
The Journal of organic chemistry 2006;71(7):2587-99.
2006: Cohen Frederick; Overman Larry E
Enantioselective total synthesis of batzelladine F and definition of its structure.
Journal of the American Chemical Society 2006;128(8):2604-8.
2006: Cohen Frederick; Overman Larry E
Evolution of a strategy for the synthesis of structurally complex batzelladine alkaloids. Enantioselective total synthesis of the proposed structure of batzelladine F and structural revision.
Journal of the American Chemical Society 2006;128(8):2594-603.
2006: Overman Larry E; Velthuisen Emile J
Scope and facial selectivity of the Prins-pinacol synthesis of attached rings.
The Journal of organic chemistry 2006;71(4):1581-7.
2005: Madin Andrew; O'Donnell Christopher J; Oh Taeboem; Old David W; Overman Larry E; Sharp Matthew J
Use of the intramolecular Heck reaction for forming congested quaternary carbon stereocenters. Stereocontrolled total synthesis of (+/-)-gelsemine.
Journal of the American Chemical Society 2005;127(51):18054-65.
2005: Earley William G; Jacobsen Jon E; Madin Andrew; Meier G Patrick; O'Donnell Christopher J; Oh Taeboem; Old David W; Overman Larry E; Sharp Matthew J
Aza-cope rearrangement-mannich cyclizations for the formation of complex tricyclic amines: stereocontrolled total synthesis of (+/-)-gelsemine.
Journal of the American Chemical Society 2005;127(51):18046-53.
2005: Overman Larry E; Rhee Young Ho
Total synthesis of (-)-crambidine and definition of the relative configuration of its unique tetracyclic guanidinium core.
Journal of the American Chemical Society 2005;127(44):15652-8.
2005: Dounay Amy B; Overman Larry E; Wrobleski Aaron D
Sequential catalytic asymmetric Heck-iminium ion cyclization: enantioselective total synthesis of the Strychnos alkaloid minfiensine.
Journal of the American Chemical Society 2005;127(29):10186-7.
2005: Adhikari Susanta; Caille Sebastien; Hanbauer Martin; Ngo Vinh X; Overman Larry E
Asymmetric construction of quaternary carbon stereocenters: high stereoselection in Mukaiyama aldol reactions of 2-siloxyindoles with chiral aldehydes.
Organic letters 2005;7(13):2795-7.
2005: Kirsch Stefan F; Overman Larry E
Catalytic asymmetric intramolecular aminopalladation: improved palladium(II) catalysts.
The Journal of organic chemistry 2005;70(7):2859-61.
2005: Aron Zachary D; Overman Larry E
Total synthesis and properties of the crambescidin core zwitterionic acid and crambescidin 359.
Journal of the American Chemical Society 2005;127(10):3380-90.
2005: Kirsch Stefan F; Overman Larry E
Catalytic asymmetric synthesis of chiral allylic esters.
Journal of the American Chemical Society 2005;127(9):2866-7.
2005: Douglas Christopher J; Hiebert Sheldon; Overman Larry E
Toward an enantioselective total synthesis of sarain A: construction of an advanced intermediate and rearrangement of the sarain A core under mild conditions.
Organic letters 2005;7(5):933-6.
2005: Aron Zachary D; Overman Larry E
Stereocontrolled synthesis of angularly substituted 1-azabicyclic rings by cationic 2-aza-cope rearrangements.
Organic letters 2005;7(5):913-6.
2005: Anderson Carolyn E; Donde Yariv; Douglas Christopher J; Overman Larry E
Catalytic asymmetric synthesis of chiral allylic amines. Evaluation of ferrocenyloxazoline palladacycle catalysts and imidate motifs.
The Journal of organic chemistry 2005;70(2):648-57.
2004: Burke Brenda J; Overman Larry E
Enantioselective synthesis of six-membered palladacycles having metal-bound stereogenic carbons: isolation and reactivity of palladacycles containing readily accessible beta-hydrogens.
Journal of the American Chemical Society 2004;126(51):16820-33.
2004: Kirsch Stefan F; Overman Larry E; Watson Mary P
Monomeric cobalt oxazoline palladacycles (COP). Useful catalysts for catalytic asymmetric rearrangement of allylic trichloroacetimidates.
The Journal of organic chemistry 2004;69(23):8101-4.
2004: Huang Audris; Kodanko Jeremy J; Overman Larry E
Asymmetric synthesis of pyrrolidinoindolines. Application for the practical total synthesis of (-)-phenserine.
Journal of the American Chemical Society 2004;126(43):14043-53.
2004: Overman Larry E; Velthuisen Emile J
Stereocontrolled construction of either stereoisomer of 12-oxatricyclo[6.3.1.0(2,7)]dodecanes using Prins-pinacol reactions.
Organic letters 2004;6(21):3853-6.
2004: Olszewski Allison; Sato Ken; Aron Zachary D; Cohen Frederick; Harris Aleishia; McDougall Brenda R; Robinson W Edward; Overman Larry E; Weiss Gregory A
Guanidine alkaloid analogs as inhibitors of HIV-1 Nef interactions with p53, actin, and p56lck.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(39):14079-84.
2004: Bewley Carole A; Ray Satyajit; Cohen Frederick; Collins Shawn K; Overman Larry E
Inhibition of HIV-1 envelope-mediated fusion by synthetic batzelladine analogues.
Journal of natural products 2004;67(8):1319-24.
2004: Peterson Emily A; Overman Larry E
Contiguous stereogenic quaternary carbons: a daunting challenge in natural products synthesis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(33):11943-8.
2004: Aron Zachary D; Pietraszkiewicz Halina; Overman Larry E; Valeriote Fredrick; Cuevas Carman
Synthesis and anticancer activity of side chain analogs of the crambescidin alkaloids.
Bioorganic & medicinal chemistry letters 2004;14(13):3445-9.
2004: Collins Shawn K; McDonald Andrew I; Overman Larry E; Rhee Young Ho
Enantioselective total synthesis of (-)-dehydrobatzelladine C. [structure: see text]
Organic letters 2004;6(8):1253-5.
2004: Douglas Christopher J; Overman Larry E
Catalytic asymmetric synthesis of all-carbon quaternary stereocenters.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(15):5363-7.
2004: Aron Zachary D; Overman Larry E
The tethered Biginelli condensation in natural product synthesis.
Chemical communications (Cambridge, England) 2004;(3):253-65.
2003: Brüggemann Markus; McDonald Andrew I; Overman Larry E; Rosen Mark D; Schwink Lothar; Scott Jeremy P
Total synthesis of (+/-)-didehydrostemofoline (asparagamine A) and (+/-)-isodidehydrostemofoline.
Journal of the American Chemical Society 2003;125(50):15284-5.
2003: Cohen Frederick; Collins Shawn K; Overman Larry E
Assembling polycyclic bisguanidine motifs resembling batzelladine alkaloids by double tethered Biginelli condensations.
Organic letters 2003;5(23):4485-8.
2003: Anderson Carolyn E; Overman Larry E
Catalytic asymmetric rearrangement of allylic trichloroacetimidates. A practical method for preparing allylic amines and congeners of high enantiomeric purity.
Journal of the American Chemical Society 2003;125(41):12412-3.
2003: Overman Larry E; Pennington Lewis D
Strategic use of pinacol-terminated Prins cyclizations in target-oriented total synthesis.
The Journal of organic chemistry 2003;68(19):7143-57.
2003: Dounay Amy B; Overman Larry E
The asymmetric intramolecular Heck reaction in natural product total synthesis.
Chemical reviews 2003;103(8):2945-64.
2003: Kodanko Jeremy J; Overman Larry E
Enantioselective total syntheses of the cyclotryptamine alkaloids hodgkinsine and hodgkinsine B.
Angewandte Chemie (International ed. in English) 2003;42(22):2528-31.
2003: Overman Larry E; Peterson Emily A
Enantioselective total synthesis of the cyclotryptamine alkaloid idiospermuline.
Angewandte Chemie (International ed. in English) 2003;42(22):2525-8.
2003: Corminboeuf Olivier; Overman Larry E; Pennington Lewis D
Enantioselective total synthesis of briarellins E and F: the first total syntheses of briarellin diterpenes.
Journal of the American Chemical Society 2003;125(22):6650-2.
2003: Dounay Amy B; Hatanaka Keiko; Kodanko Jeremy J; Oestreich Martin; Overman Larry E; Pfeifer Lance A; Weiss Matthew M
Catalytic asymmetric synthesis of quaternary carbons bearing two aryl substituents. Enantioselective synthesis of 3-alkyl-3-aryl oxindoles by catalytic asymmetric intramolecular heck reactions.
Journal of the American Chemical Society 2003;125(20):6261-71.
2003: Overman Larry E; Owen Carolyn E; Pavan Mary M; Richards Christopher J
Catalytic asymmetric rearrangement of allylic N-aryl trifluoroacetimidates. A useful method for transforming prochiral allylic alcohols to chiral allylic amines.
Organic letters 2003;5(11):1809-12.
2003: Corminboeuf Olivier; Overman Larry E; Pennington Lewis D
Total synthesis of the reputed structure of alcyonin and reassignment of its structure.
Organic letters 2003;5(9):1543-6.
2002: Bélanger Guillaume; Hong Fang-Tsao; Overman Larry E; Rogers Bruce N; Tellew John E; Trenkle William C
Stereocontrolled synthesis of triazacyclopenta[cd]pentalenes by intramolecular 1,3-dipolar cycloaddition reactions of azomethine imines.
The Journal of organic chemistry 2002;67(22):7880-3.
2002: Overman Larry E; Owen Carolyn E; Zipp G Greg
Diastereoselective lithiation of (eta6-arene)dicarbonyltriphenylphosphane chromium(0) oxazoline complexes--direct preparation of enantiopure complexes having planar chiral fragments of either configuration.
Angewandte Chemie (International ed. in English) 2002;41(20):3884-7.
2002: Overman Larry E; Wolfe John P
New cationic olefin cyclization-pinacol reactions. Ring-expanding cyclopentane annulations that directly install useful functionality in the cyclopentane ring.
The Journal of organic chemistry 2002;67(18):6421-9.
2002: Lebsack Alec D; Link J T; Overman Larry E; Stearns Brian A
Enantioselective total synthesis of quadrigemine C and psycholeine.
Journal of the American Chemical Society 2002;124(31):9008-9.
2002: Hynes John; Nasser Talal; Overman Larry E; Watson Donald A
Preparation of alpha-sulfenyl enones by thermal fragmentation of beta-sulfenyl enol triflates.
Organic letters 2002;4(6):929-31.
2002: Kamenecka Theodore M; Overman Larry E; Ly Sakata Sylvie K
Construction of substituted cyclohexanones by reductive cyclization of 7-oxo-2,8-alkadienyl esters.
Organic letters 2002;4(1):79-82.
2002: Overman Larry E; Remarchuk Travis P
Catalytic asymmetric intramolecular aminopalladation: enantioselective synthesis of vinyl-substituted 2-oxazolidinones, 2-imidazolidinones, and 2-pyrrolidinones.
Journal of the American Chemical Society 2002;124(1):12-3.
2001: Cohen F; Overman L E
Enantioselective total synthesis of batzelladine F: structural revision and stereochemical definition.
Journal of the American Chemical Society 2001;123(43):10782-3.
2001: Govek S P; Overman L E
Total synthesis of asperazine.
Journal of the American Chemical Society 2001;123(38):9468-9.
2001: Overman L E; Paone D V
Enantioselective total syntheses of ditryptophenaline and ent-WIN 64821.
Journal of the American Chemical Society 2001;123(38):9465-7.
2001: MacMillan D W; Overman L E; Pennington L D
A general strategy for the synthesis of cladiellin diterpenes: enantioselective total syntheses of 6-acetoxycladiell-7(16),11-dien-3-ol (deacetoxyalcyonin acetate), cladiell-11-ene-3,6,7-triol, sclerophytin A, and the initially purported structure of sclerophytin A.
Journal of the American Chemical Society 2001;123(37):9033-44.
2001: Lebsack A D; Overman L E; Valentekovich R J
Enantioselective total synthesis of shahamin K.
Journal of the American Chemical Society 2001;123(20):4851-2.
2001: Overman L E; Wolfe J P
Synthesis of polycyclic guanidines by cyclocondensation reactions of N-amidinyliminium ions.
The Journal of organic chemistry 2001;66(9):3167-75.
2001: Kamatani A; Overman L E
A new asymmetric synthesis of trans-hydroisoquinolones.
Organic letters 2001;3(8):1229-32.
2001: Cohen F; MacMillan D W; Overman L E; Romero A
Stereoselection in the Prins-pinacol synthesis of acyltetrahydrofurans.
Organic letters 2001;3(8):1225-8.
2001: Gallou F; MacMillan D W; Overman L E; Paquette L A; Pennington L D; Yang J
Enantioselective syntheses of authentic sclerophytin A, sclerophytin B, and cladiell-11-ene-3,6,7-triol.
Organic letters 2001;3(1):135-7.
2000: Hoyt S B; Overman L E
Investigation of a dialkylation approach for enantioselective construction of vicinal quaternary stereocenters.
Organic letters 2000;2(20):3241-4.
2000: Overman L E; Pennington L D
Total synthesis of the supposed structure of (-)-sclerophytin A and an improved route to (-)-7-deacetoxyalcyonin acetate.
Organic letters 2000;2(17):2683-6.
2000: Hanaki N; Link J T; MacMillan D W; Overman L E; Trankle W G; Wurster J A
Stereoselection in the prins-pinacol synthesis of 2,2-disubstituted 4-acyltetrahydrofurans. Enantioselective synthesis of (-)-citreoviral.
Organic letters 2000;2(2):223-6.
1999: Cohen F; Overman L E; Sakata S K
Asymmetric total synthesis of batzelladine D.
Organic letters 1999;1(13):2169-72.

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