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Michael Owen

Research Profile

Disorders

Physiology

Genes & Molecular Sequences

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Great Britain

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TOP 3
Marian Hamshere; Peter Holmans; Ian Jones; Lesley Jones; K S Kendler; J Kranz; D Morris; T O'Neill; Michael J Owen; S Purcell; A L Richards; B Riley; P Sklar; R Smith; J T R Walters; Aiden Corvin; Nick Craddock; Liz Forty; Michael Gill; Katherine Gordon-Smith; Elaine Green; Detelina Grozeva; Michael C O'Donovan
Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC.
D H Kavanagh; Michael C O'Donovan; Sarah Dwyer; Michael J Owen
The ENCODE project: implications for psychiatric genetics.
Elaine K Green; Detelina Grozeva; Marian Hamshere; Ian Richard Jones; Lesley Jones; Peter McGuffin; J L Moran; Michael C O'Donovan; Michael J Owen; S Purcell; E Russell; P Sklar; Anne Farmer; Liz Forty; Katherine Gordon-Smith; Nick Craddock
Association at SYNE1 in both bipolar disorder and recurrent major depression.

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All Publications

2013: Marian Hamshere; Peter Holmans; Ian Jones; Lesley Jones; K S Kendler; J Kranz; D Morris; T O'Neill; Michael J Owen; S Purcell; A L Richards; B Riley; P Sklar; R Smith; J T R Walters; Aiden Corvin; Nick Craddock; Liz Forty; Michael Gill; Katherine Gordon-Smith; Elaine Green; Detelina Grozeva; Michael C O'Donovan
Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC.
Molecular psychiatry 2013;18(6):708-12.
2013: D H Kavanagh; Michael C O'Donovan; Sarah Dwyer; Michael J Owen
The ENCODE project: implications for psychiatric genetics.
Molecular psychiatry 2013;18(5):540-2.
2013: Elaine K Green; Detelina Grozeva; Marian Hamshere; Ian Richard Jones; Lesley Jones; Peter McGuffin; J L Moran; Michael C O'Donovan; Michael J Owen; S Purcell; E Russell; P Sklar; Anne Farmer; Liz Forty; Katherine Gordon-Smith; Nick Craddock
Association at SYNE1 in both bipolar disorder and recurrent major depression.
Molecular psychiatry 2013;18(5):614-7.
2013: Hywel J Williams; George Kirov; Stephen Monks; Kieran C Murphy; Michael C O'Donovan; Michael J Owen
Schizophrenia two-hit hypothesis in velo-cardio facial syndrome.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2013;162B(2):177-82.
2013: Gary Donohoe; C Fahey; I Giegling; M Gill; A Hargreaves; A M Hartmann; Hans-Jürgen Möller; D W Morris; P Muglia; M C O'Donovan; Michael J Owen; E J Rose; D Rujescu; D Tropea; J Walters; S Bellini; E Cummins; A Corvin
Neuropsychological effects of the CSMD1 genome-wide associated schizophrenia risk variant rs10503253.
Genes, brain, and behavior 2013;12(2):203-9.
2013: Jade Chapman; Amy Gerrish; Denise Harold; Paul Hollingworth; Peter Holmans; Dobril Ivanov; Michael C O'Donovan; Michael J Owen; Elliott Rees; Rebecca Sims; Alexandra Stretton; Julie Williams; George Kirov
A genome-wide study shows a limited contribution of rare copy number variants to Alzheimer's disease risk.
Human molecular genetics 2013;22(4):816-24.
2013: Ruth Sellers; Daniel J Smith; Ajay K Thapar; Stephan Collishaw; Nick Craddock; Gordon Harold; Becky Mars; Michael J Owen; Robert Potter; Frances Rice; Anita Thapar
Risk of psychopathology in adolescent offspring of mothers with psychopathology and recurrent depression.
The British journal of psychiatry : the journal of mental science 2013;202():108-14.
2013: J J H Rucker; S W Scherer; A Schosser; Rudolf Uher; KJ Aitchison; M R Barnes; Gerome Breen; S Cohen-Woods; Nick Craddock; Ian W Craig; A E Farmer; Michael Gill; F Holsboer; Ian Jones; L Jones; Ania Korszun; C M Lewis; Wolfgang Maier; Ole Mors; Pierandrea Muglia; Michael J Owen; I Pedroso; D Pinto; Martin Preisig; J Rice; Marcella Rietschel; M Rivera; Peter McGuffin
Genome-wide association analysis of copy number variation in recurrent depressive disorder.
Molecular psychiatry 2013;18(2):183-9.
2013: Kathryn J Peall; Michael Samuel; Daniel J Smith; Martin Smith; Adrian J Waite; Mark Wardle; Thomas T Warner; Cathy White; Alan Whone; Narinder Bajaj; Derek J Blake; Patrick F Chinnery; Tammy Hedderly; Philip Jardine; Mary D King; George Kirov; Manju A Kurian; Jean-Pierre Lin; Andrew Lux; Bryan Lynch; Timothy Lynch; Sean O'Riordan; Michael J Owen; Hardev Pall; Huw R Morris
SGCE mutations cause psychiatric disorders: clinical and genetic characterization.
Brain : a journal of neurology 2013;136(Pt 1):294-303.
2012: Hywel J Williams; Michael J Owen; Sarah Dwyer; Lyudmila Georgieva; George Kirov; Michael C O'Donovan
Absence of de novo point mutations in exons of GRIN2B in a large schizophrenia trio sample.
Schizophrenia research 2012;141(2-3):274-6.
2012: Menachem Fromer; Robert E Handsaker; Christina M Hultman; George Kirov; Steven A McCarroll; Jennifer L Moran; Michael C O'Donovan; Michael J Owen; Eric Banks; Sarah E Bergen; Kimberly Chambert; Douglas M Ruderfer; Pamela Sklar; Patrick F Sullivan; Shaun M Purcell
Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth.
American journal of human genetics 2012;91(4):597-607.
2012: Ajay Thapar; Jon Heron; Rhys Bevan Jones; Glyn Lewis; Michael J Owen; Stanley Zammit
Trajectories of change in self-reported psychotic-like experiences in childhood and adolescence.
Schizophrenia research 2012;140(1-3):104-9.
2012: Valentina Moskvina; Nicholas Craddock; Peter Holmans; Michael J Owen; Karl Michael Schmidt; Alexey Vedernikov; Michael C O'Donovan
Permutation-based approaches do not adequately allow for linkage disequilibrium in gene-wide multi-locus association analysis.
European journal of human genetics : EJHG 2012;20(8):890-6.
2012: Tom Fowler; Michael J Owen; Stanley Zammit; Finn Rasmussen
A population-based study of shared genetic variation between premorbid IQ and psychosis among male twin pairs and sibling pairs from Sweden.
Archives of general psychiatry 2012;69(5):460-6.
2012: Petroula Proitsi; Suzanne J Reeves; David C Rubinsztein; Julie Williams; Nicola Archer; Carol Brayne; Michael Gill; Gillian Hamilton; Paul Hollingworth; Conrad Iyegbe; Brian Lawlor; Simon Lovestone; Michelle K Lupton; Belinda M Martin; Michael J Owen; John F Powell
Association of serotonin and dopamine gene pathways with behavioral subphenotypes in dementia.
Neurobiology of aging 2012;33(4):791-803.
2012: Detelina Grozeva; Matthew Hurles; George Kirov; Michael C O'Donovan; Michael J Owen; Chris P Barnes; Donald F Conrad; Nick Craddock
Independent estimation of the frequency of rare CNVs in the UK population confirms their role in schizophrenia.
Schizophrenia research 2012;135(1-3):1-7.
2012: Evangelia Stergiakouli; Nigel Williams; Irina Zaharieva; Michael Gill; Marian Hamshere; Ziarah Hawi; Peter Holmans; Lindsey Kent; Kate Langley; Michael O'Donovan; Michael J Owen; Anita Thapar
Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD.
The American journal of psychiatry 2012;169(2):186-94.
2012: George Kirov; Noboru H Komiyama; J Moran; Ivan Nikolov; Michael C O'Donovan; P I Olason; A Bayés; Yvonne Böttcher; K Chambert; Jyoti S Choudhary; Mark Collins; E Fernandez; M Fjodorova; Lyudmila Georgieva; S G N Grant; Detelina Grozeva; Peter Holmans; M Ikeda; Dobril Ivanov; Andrew J Pocklington; S Purcell; E Rees; D Ruderfer; P Sklar; Hreinn Stefansson; K Stefansson; Draga Toncheva; R Wollerton; Louie van de Lagemaat; Michael J Owen
De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.
Molecular psychiatry 2012;17(2):142-53.
2012: A L Richards; A R Sanders; P M Visscher; Michael J Owen; S Purcell; Nick Craddock; P V Gejman; Peter Holmans; Lesley Jones; George Kirov; Douglas F Levinson; Valentina Moskvina; Michael C O'Donovan
Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain.
Molecular psychiatry 2012;17(2):193-201.
2012: Alexis Economou; Michelle Grey; Nick Craddock; Ronan Anthony Lyons; Joanna McGregor; Michael J Owen; Vaughn Price; Sue Thomson; James Tr Walters; Keith Lloyd
The health informatics cohort enhancement project (HICE): using routinely collected primary care data to identify people with a lifetime diagnosis of psychotic disorder.
BMC research notes 2012;5():95.
2012: Helen L Fisher; Georgina M Hosang; Ian Jones; Lisa Jones; Robert Keers; Ania Korszun; Sarah Cohen-Woods; Nick Craddock; Ian W Craig; Anne E Farmer; Michael J Owen; Georgia Powell-Smith; Maria Tropeano; Rudolf Uher; Peter McGuffin
Stressful life events and the serotonin transporter gene (5-HTT) in recurrent clinical depression.
Journal of affective disorders 2012;136(1-2):189-93.
2011: Elliott Rees; Valentina Moskvina; Michael C O'Donovan; Michael J Owen; George Kirov
De novo rates and selection of schizophrenia-associated copy number variants.
Biological psychiatry 2011;70(12):1109-14.
2011: Marian Hamshere; Peter Holmans; Lisa A Jones; Geraldine M McCarthy; Peter McGuffin; Kieran C Murphy; Nadine Norton; Michael C O'Donovan; Michael J Owen; Robert D Sanders; Hywel J Williams; Nigel M Williams; Stanley Zammit; Nicholas Craddock; MY Gray; Alastair G Cardno
Phenotype evaluation and genomewide linkage study of clinical variables in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(8):929-40.
2011: L S Carroll; George Kirov; Michael C O'Donovan; J Walters; Hywel J Williams; Michael J Owen
Mutation screening of the 3q29 microdeletion syndrome candidate genes DLG1 and PAK2 in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(7):844-9.
2011: Hywel J Williams; Sarah Dwyer; Valentina Moskvina; Michael J Owen; Giancarlo Russo; Rhodri L Smith; Michael C O'Donovan
Association between TCF4 and schizophrenia does not exert its effect by common nonsynonymous variation or by influencing cis-acting regulation of mRNA expression in adult human brain.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(7):781-4.
2011: Rebecca Sims; A David Smith; Alexandra Stretton; Charlene Thomas; Stephen Todd; Richard Abraham; Nicholas J Bass; Carol Brayne; Kristelle S Brown; Jade Chapman; John Collinge; David Craig; Kimberley Dowzell; Sarah Dwyer; Nick C Fox; Amy Gerrish; Michael Gill; Hugh Gurling; John Hardy; Denise Harold; Paul Hollingworth; Peter A Holmans; Clive Holmes; Dobril Ivanov; Janet A Johnston; Lesley Jones; Nicola Jones; Patrick G Kehoe; Brian Lawlor; Gill Livingston; Seth Love; Simon Lovestone; Michelle K Lupton; Aoibhinn Lynch; David Mann; Bernadette McGuiness; Andrew McQuillin; Simon Mead; Kevin Morgan; Valentina Moskvina; Michael O'Donovan; Michael J Owen; Jaspreet Singh Pahwa; Peter A Passmore; John Powell; Petroula Proitsi; Martin N Rossor; David C Rubinsztein; Julie Williams
No evidence that extended tracts of homozygosity are associated with Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(7):764-71.
2011: Kate Langley; Joanna Martin; Michael O'Donovan; Michael J Owen; Evangelia Stergiakouli; Sharifah Shameem Agha; Charlotte Davies; Peter Holmans; Nigel Williams; Anita Thapar
Clinical and cognitive characteristics of children with attention-deficit hyperactivity disorder, with and without copy number variants.
The British journal of psychiatry : the journal of mental science 2011;199(5):398-403.
2011: Stanley Zammit; Michael J Owen; Jonathan Evans; Jon Heron; Glyn Lewis
Cannabis, COMT and psychotic experiences.
The British journal of psychiatry : the journal of mental science 2011;199(5):380-5.
2011: X Chen; K Chowdari; S Cichon; A Corvin; N J Craddock; A Darvasi; S Djurovic; J Duan; A H Fanous; P V Gejman; I Giegling; M Gill; A Guo; H M D Gurling; T Hansen; C Hultman; A Ingason; K S Kendler; G K Kirov; G Lee; T Lencz; D F Levinson; D Lewis; P Lichtenstein; antonio macedo; B S Maher; Anil Malhotra; A McQuillin; D W Morris; V Nimgaonkar; M M Nöethen; M C O'Donovan; F A O'Neill; R Ophoff; Michael J Owen; C N Pato; M T Pato; J Pimm; S M Purcell; W Qin; M Rietschel; D Rujescu; A Sanders; S Schwab; E Scolnick; J Shi; P Sklar; D St Clair; R E Straub; P F Sullivan; E van den Oord; D Walsh; D R Weinberger; T Werge; D Wildenauer; Z Zhao; O A Andreassen; J Blackman; D H R Blackwood; M Bronstein; R M Cantor; J Chen
GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia.
Molecular psychiatry 2011;16(11):1117-29.
2011: Stacy Steinberg; Eric Strengman; Jaana Suvisaari; Lars Terenius; Unnur Thorsteinsdottir; Sarah Tosato; Annamari Tuulio-Henriksson; Leonard van den Berg; Ruud van Winkel; Evangelos Vassos; Jan Veldink; Nicholas Walker; Thomas Werge; Carsten Wiuf; Torben Ørntoft; Lilia Abramova; Ingrid Agartz; Ole A Andreassen; Celso Arango; Manuel Arrojo; István Bitter; Anders D Børglum; René Breuer; Angel Carracedo; Claus Christiansen; Sven Cichon; David A Collier; Javier Costas; Nick Craddock; marc de hert; Simone de Jong; Ditte Demontis; Michael Didriksen; Srdjan Djurovic; Hannelore Ehrenreich; Gillian Fraser; Ina Giegling; Birte Glenthøj; Vera Golimbet; Omar Gustafsson; Mads V Hollegaard; David M Hougaard; Johanna Huttenlocher; Andres Ingason; Erik G Jönsson; Gesche Jürgens; Vasily Kaleda; Gunter Kenis; Lambertus A Kiemeney; Augustine Kong; Jouko Lönnqvist; Valentina Magni; Manuel Mattheisen; Ingrid Melle; Ole Mors; Preben B Mortensen; Pierandrea Muglia; Robin Murray; Merete Nordentoft; Markus M Nöthen; Michael C O'Donovan; Roel A Ophoff; Michael J Owen; Sergi Papiol; Tiina Paunio; Leena Peltonen; Hannes Petursson; Olli P H Pietiläinen; János M Réthelyi; Michele Ribolsi; Marcella Rietschel; Moritz Rossner; I Alex Rubino; Mirella Ruggeri; Dan Rujescu; Julio Sanjuán; Engilbert Sigurdsson; Alberto Siracusano; Swetlana Sperling; David St Clair; Hreinn Stefansson; Kari Stefansson
Common variants at VRK2 and TCF4 conferring risk of schizophrenia.
Human molecular genetics 2011;20(20):4076-81.
2011: A Yosifova; I Zaharieva; Ivanka Dimova; I Gerdjikov; S Hadjidekova; N Kamatani; Y Kamatani; S Karachanak; George Kirov; M Kubo; N Madjirova; vihra milanova; Taisei Mushiroda; Michael C O'Donovan; Michael J Owen; N Poryazova; D Stoianov; A Takahashi; T Tolev; Draga Toncheva; R Vazharova; Y Nakamura
Genome-wide association study on bipolar disorder in the Bulgarian population.
Genes, brain, and behavior 2011;10(7):789-97.
2011: A Schosser; F Tozzi; Pierandrea Muglia; Michael J Owen; J Perry; E B Binder; S Cohen-Woods; N Craddock; Ian W Craig; Enrico Domenici; A E Farmer; D Gaysina; J Gray; C Gunasinghe; F Holsboer; L Jones; Ania Korszun; Peter McGuffin
A follow-up case-control association study of tractable (druggable) genes in recurrent major depression.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(6):640-50.
2011: Douglas M Ruderfer; Pamela Sklar; K Chambert; G Kirov; J L Moran; M C O'Donovan; Michael J Owen; S M Purcell
A family-based study of common polygenic variation and risk of schizophrenia.
Molecular psychiatry 2011;16(9):887-8.
2011: Erik Boot; Don Linszen; Declan G Murphy; Kieran C Murphy; Michael J Owen; Ann Swillen; Frank Baas; Jan Booij; Janneke Zinkstok; Therese van Amelsvoort
COMT Val(158) met genotype and striatal D(2/3) receptor binding in adults with 22q11 deletion syndrome.
Synapse (New York, N.Y.) 2011;65(9):967-70.
2011: Gerome Breen; Shyama Brewster; Amy W Butler; Sarah Cohen-Woods; Nick Craddock; Ian Craig; Anne E Farmer; Nicholas W Galwey; Mike Gill; Lisa Jones; Jo Knight; Ania Korszun; Cathryn M Lewis; Wolfgang Maier; Lefkos Middleton; Ole Mors; Pierandrea Muglia; Mandy Ng; Michael J Owen; Julia Perry; Martin Preisig; John Rice; Marcella Rietschel; Federica Tozzi; Ruchi Upmanyu; Edwin J C G van den Oord; Bradley Todd Webb; Peter McGuffin
A genome-wide significant linkage for severe depression on chromosome 3: the depression network study.
The American journal of psychiatry 2011;168(8):840-7.
2011: Sarah Dwyer; Ian Jones; Lesley Jones; Michael J Owen; J Walters; H Williams; Nick Craddock; Michael C O'Donovan
Investigation of rare non-synonymous variants at ABCA13 in schizophrenia and bipolar disorder.
Molecular psychiatry 2011;16(8):790-1.
2011: Paul Hollingworth; Lesley Jones; Michael J Owen; Denise Harold; Julie Williams
Alzheimer's disease genetics: current knowledge and future challenges.
International journal of geriatric psychiatry 2011;26(8):793-802.
2011: Valentina Moskvina; Bertram Müller-Myhsok; Michael J Owen; Nick Craddock; Elaine Green; Peter Holmans; Tony Kam-Thong; Michael C O'Donovan
An examination of single nucleotide polymorphism selection prioritization strategies for tests of gene-gene interaction.
Biological psychiatry 2011;70(2):198-203.
2011: Rhodri Ll Smith; Hywel Williams; Alex Richards; Sarah Dwyer; George Kirov; Deborah Knight; Michael C O'Donovan; Michael J Owen
Analysis of neurogranin (NRGN) in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(5):532-5.
2011: Elaine K Green; Detelina Grozeva; R Sims; Rachel Raybould; Liz Forty; Katherine Gordon-Smith; E Russell; D St Clair; A H Young; Ian Nicol Ferrier; George Kirov; Ian Jones; Lesley Jones; Michael J Owen; Michael C O'Donovan; Nick Craddock
DISC1 exon 11 rare variants found more commonly in schizoaffective spectrum cases than controls.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(4):490-2.
2011: Paul Hollingworth; Peter A Holmans; Clive Holmes; Nigel M Hooper; Michael Hüll; M Arfan Ikram; Dobril Ivanov; Frank Jessen; Karl-Heinz Jöckel; Lesley Jones; Nicola Jones; Palmi V Jonsson; Thorlakur Jonsson; John S K Kauwe; Patrick G Kehoe; Norman Klopp; Heike Kölsch; Johannes Kornhuber; Michael Krawczak; Jean-Charles Lambert; Mark Lathrop; Lenore J Launer; Brian Lawlor; Federico Licastro; Gill Livingston; Oscar L Lopez; Seth Love; Simon Lovestone; Michelle K Lupton; Aoibhinn Lynch; Wolfgang Maier; Michelangelo Mancuso; David Mann; Ignacio Mateo; Manuel Mayhaus; Kevin Mayo; Bernadette McGuinness; Andrew McQuillin; Simon Mead; Susanne Moebus; Kevin Morgan; John C Morris; Valentina Moskvina; Thomas W Mühleisen; Benedetta Nacmias; S Nicolhaus; Markus M Nöthen; Petra Nowotny; Michael O'Donovan; Michael J Owen; Jaspreet Singh Pahwa; V Shane Pankratz; Francesco Panza; Florence Pasquier; Peter A Passmore; Ronald C. Petersen; Paola Piccardi; Alberto Pilotto; Elisa Porcellini; John Powell; Petroula Proitsi; Alex Richards; Caterina Riehle; Matthias Riemenschneider; Martin N Rossor; David C Rubinsztein; Dan Rujescu; Eckart Rüther; Sigrid B Sando; Elio Scarpini; Stefan Schreiber; Britta Schürmann; Davide Seripa; Sudha Seshadri; Christopher E Shaw; Gabriele Siciliano; Rebecca Sims; Andrew B Singleton; Kristel Sleegers; A David Smith; Jon Snaedal; Hilkka Soininen; Vincenzo Solfrizzi; Sandro Sorbi; Hreinn Stefansson; Kari Stefansson; Stacy Steinberg; Alexandra Stretton; Charlene Thomas; Stephen Todd; Magda Tsolaki; Christophe Tzourio; Christine Van Broeckhoven; Hendrik van den Bussche; Cornelia M van Duijn; Emma R L C Vardy; Stefan Wagenpfeil; Donald Warden; H-Erich Wichmann; Caroline Widdowson; Gordon Wilcock; Jan O Aasly; Richard Abraham; Ammar Al-Chalabi; Annick Alpérovitch; Victoria Alvarez; Philippe Amouyel; Giorgio Annoni; Beatrice Arosio; Maria Barcikowska; Nicholas J Bass; Helen Beaumont; Claudine Berr; Karolien Bettens; Sigurbjörn Björnsson; Paolo Bosco; Paola Bossù; Carol Brayne; Monique Breteler; Alexis Brice; Kristelle S Brown; Maria J Bullido; Dominique Campion; Minerva M Carrasquillo; Jade Chapman; Vincent Chouraki; John Collinge; Onofre Combarros; Eliecer Coto; David Craig; Carlos Cruchaga; Jean-François Dartigues; Peter P De Deyn; Marc Delepine; Panagiotis Deloukas; Anita L DeStefano; Martin Dichgans; dennis dickson; Kimberley Dowzell; Sebastiaan Engelborghs; Jacques Epelbaum; Thomas M Feulner; Annette L Fitzpatrick; Nick C Fox; Ana Frank-Garcia; Patricia Friedrich; Lutz Frölich; Daniela Galimberti; John Gallacher; Benjamin Genier-Boley; Amy Gerrish; Ina Giegling; Michael Gill; Alison Goate; Neill R Graff-Radford; Rita Guerreiro; Hugh Gurling; Rhian Gwilliam; Harald Hampel; Marian L Hamshere; Didier Hannequin; Olivier Hanon; John Hardy; Denise Harold; Reiner Heun; Isabella Heuser; Mikko Hiltunen; Jens Wiltfang; Zbigniew K Wszolek; Steven G Younkin; Diana Zelenika; Julie Williams
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
Nature genetics 2011;43(5):429-35.
2011: Marian Hamshere; Peter Holmans; Ian Richard Jones; Lesley Jones; George Kirov; Peter McGuffin; Andrew McQuillin; Valentina Moskvina; Michael C O'Donovan; Michael J Owen; S Purcell; P Sklar; D St Clair; A H Young; Anne Farmer; Ian Nicol Ferrier; Elaine K Green; Detelina Grozeva; H Gurling; N Bass; Nick Craddock
Polygenic dissection of the bipolar phenotype.
The British journal of psychiatry : the journal of mental science 2011;198(4):284-8.
2011: Andrés Ingason; George Kirov; Ina Giegling; Thomas Hansen; Anthony R Isles; Klaus D Jakobsen; Kari T Kristinsson; Louise le Roux; Omar Gustafsson; Nick Craddock; Hans-Jürgen Möller; Andrew McQuillin; Pierandrea Muglia; Sven Cichon; Marcella Rietschel; Roel A Ophoff; Srdjan Djurovic; Ole A Andreassen; Olli P H Pietiläinen; Leena Peltonen; Emma Dempster; David A Collier; David St Clair; Henrik B Rasmussen; Birte Y Glenthøj; Lambertus A Kiemeney; Barbara Franke; Sarah Tosato; Chiara Bonetto; Evald Saemundsen; Stefán J Hreidarsson; Markus M Nöthen; Hugh Gurling; Michael C O'Donovan; Michael J Owen; Engilbert Sigurdsson; Hannes Petursson; Hreinn Stefansson; Dan Rujescu; Kari Stefansson; Thomas Werge
Maternally derived microduplications at 15q11-q13: implication of imprinted genes in psychotic illness.
The American journal of psychiatry 2011;168(4):408-17.
2011: E Stergiakouli; Kate Langley; Hywel Williams; J Walters; Nigel M Williams; S Suren; Ina Giegling; Lawrence S Wilkinson; Michael J Owen; Michael C O'Donovan; Dan Rujescu; Anita Thapar; William Davies
Steroid sulfatase is a potential modifier of cognition in attention deficit hyperactivity disorder.
Genes, brain, and behavior 2011;10(3):334-44.
2011: H J Williams; Nadine Norton; S Dwyer; V Moskvina; I Nikolov; L Carroll; L Georgieva; N M Williams; D W Morris; E M Quinn; I Giegling; M Ikeda; J Wood; T Lencz; C Hultman; P Lichtenstein; D Thiselton; B S Maher; Anil Malhotra; B Riley; K S Kendler; M Gill; P Sullivan; P Sklar; S Purcell; V L Nimgaonkar; G Kirov; P Holmans; A Corvin; D Rujescu; N Craddock; Michael J Owen; M C O'Donovan
Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder.
Molecular psychiatry 2011;16(4):429-41.
2011: Sven Cichon; Thomas W Mühleisen; Franziska A Degenhardt; Manuel Mattheisen; Xavier Miró; Jana Strohmaier; Michael Steffens; Christian Meesters; Stefan Herms; Moritz Weingarten; Lutz Priebe; Britta Haenisch; Michael Alexander; Jennifer Vollmer; René Breuer; Christine Schmäl; Peter Tessmann; Susanne Moebus; H-Erich Wichmann; Stefan Schreiber; Bertram Müller-Myhsok; Susanne Lucae; Stéphane Jamain; Marion Leboyer; Frank Bellivier; Bruno Etain; Chantal Henry; Jean-Pierre Kahn; Simon Heath; Marian Hamshere; Michael C O'Donovan; Michael J Owen; Nick Craddock; Markus Schwarz; Helmut Vedder; Jutta Kammerer-Ciernioch; Andreas Reif; Johanna Sasse; Michael Bauer; Martin Hautzinger; Adam Wright; Philip B Mitchell; Peter R Schofield; Grant W Montgomery; Sarah E Medland; Scott D Gordon; Nicholas G Martin; Omar Gustafsson; Ole Andreassen; Srdjan Djurovic; Engilbert Sigurdsson; Stacy Steinberg; Hreinn Stefansson; Kari Stefansson; Lejla Kapur-Pojskic; Liliana Oruc; Fabio Rivas; Fermín Mayoral; Alexander Chuchalin; Gulja Babadjanova; Alexander S Tiganov; Galina Pantelejeva; Lilia I Abramova; Maria Grigoroiu-Serbanescu; Carmen C Diaconu; Piotr M Czerski; Joanna Hauser; Andreas Zimmer; Mark Lathrop; Thomas G. Schulze; Thomas F Wienker; Johannes Schumacher; Wolfgang Maier; Peter Propping; Marcella Rietschel; Markus M Nöthen
Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder.
American journal of human genetics 2011;88(3):372-81.
2011: Michael J Owen; Michael C O'Donovan; Anita Thapar; Nicholas Craddock
Neurodevelopmental hypothesis of schizophrenia.
The British journal of psychiatry : the journal of mental science 2011;198(3):173-5.
2011: Masashi Ikeda; Branko Aleksic; Yoko Kinoshita; Tomo Okochi; Kunihiro Kawashima; Itaru Kushima; Yoshihito Ito; Yukako Nakamura; Taro Kishi; Takenori Okumura; Yasuhisa Fukuo; Hywel J Williams; Marian L Hamshere; Dobril Ivanov; Toshiya INADA; Michio Suzuki; Ryota Hashimoto; Hiroshi Ujike; Masatoshi Takeda; Nick Craddock; Kozo Kaibuchi; Michael J Owen; Norio Ozaki; Michael C O'Donovan; Nakao Iwata
Genome-wide association study of schizophrenia in a Japanese population.
Biological psychiatry 2011;69(5):472-8.
2011: P Proitsi; G Hamilton; M Tsolaki; M Lupton; M Daniilidou; Paul Hollingworth; N Archer; C Foy; F Stylios; B McGuinness; S Todd; B Lawlor; M Gill; Carol Brayne; David C Rubinsztein; Michael J Owen; J Williams; David Craig; P Passmore; Simon Lovestone; John F Powell
A Multiple Indicators Multiple Causes (MIMIC) model of Behavioural and Psychological Symptoms in Dementia (BPSD).
Neurobiology of aging 2011;32(3):434-42.
2011: Riccardo Zuliani; T William J Moorhead; Mark E Bastin; Eve C Johnstone; Stephen M Lawrie; Paolo Brambilla; Michael C O'Donovan; Michael J Owen; Jeremy Hall; Andrew M McIntosh
Genetic variants in the ErbB4 gene are associated with white matter integrity.
Psychiatry research 2011;191(2):133-7.
2011: Michael J Owen
Is there a schizophrenia to diagnose?
World psychiatry : official journal of the World Psychiatric Association (WPA) 2011;10(1):34-5.
2011: Gary Donohoe; James Walters; Derek W Morris; Andreia Da Costa; Emma Rose; April Hargreaves; Katie Maher; Eimear Hayes; Ina Giegling; Annette M Hartmann; Hans-Jürgen Möller; Pierandrea Muglia; Valentina Moskvina; Michael J Owen; Michael C O'Donovan; Michael Gill; Aiden Corvin; Dan Rujescu
A neuropsychological investigation of the genome wide associated schizophrenia risk variant NRGN rs12807809.
Schizophrenia research 2011;125(2-3):304-6.
2011: Hywel J Williams; Nick Craddock; Giancarlo Russo; Marian L Hamshere; Valentina Moskvina; Sarah Dwyer; Rhodri L Smith; Elaine Green; Detelina Grozeva; Peter Holmans; Michael J Owen; Michael C O'Donovan
Most genome-wide significant susceptibility loci for schizophrenia and bipolar disorder reported to date cross-traditional diagnostic boundaries.
Human molecular genetics 2011;20(2):387-91.
2011: Alexandra Schosser; Federica Tozzi; Rudolf Uher; KJ Aitchison; Elisabeth B Binder; Gerome Breen; Amy W Butler; Sarah Cohen-Woods; Nick Craddock; Ian W Craig; Anne E Farmer; Michael Gill; Marcus Ising; Ian Jones; Lisa Jones; Ania Korszun; Susanne Lucae; Wolfgang Maier; Peter McGuffin; Ole Mors; Pierandrea Muglia; Bertram Müller-Myhsok; Mandy Y M Ng; Michael J Owen; Nader Perroud; Julia Perry; Martin Preisig; John P Rice; Marcella Rietschel; Cathryn M Lewis
Genomewide association scan of suicidal thoughts and behaviour in major depression.
PloS one 2011;6(7):e20690.
2011: Zainab Samaan; Sarah Cohen-Woods; Nick Craddock; Daria Gaysina; Lisa Jones; Ania Korszun; Peter McGuffin; Andrew Mente; Michael J Owen; Anne Farmer
Methylenetetrahydrofolate reductase gene variant (MTHFR C677T) and migraine: a case control study and meta-analysis.
BMC neurology 2011;11():66.
2011: Olivia Belbin; Kristelle Brown; Hui Shi; Christopher Medway; Richard Abraham; Peter Passmore; David Mann; A David Smith; Clive Holmes; Bernadette McGuinness; David Craig; Donald Warden; Reinhard Heun; Heike Kölsch; Seth Love; Noor Kalsheker; Julie Williams; Michael J Owen; Minerva M Carrasquillo; Steven G Younkin; Kevin Morgan; Patrick G Kehoe
A multi-center study of ACE and the risk of late-onset Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2011;24(3):587-97.
2011: Christiane Reitz; Rong Cheng; Ekaterina Rogaeva; Joseph H Lee; Shinya Tokuhiro; Fanggeng Zou; Karolien Bettens; Kristel Sleegers; Eng King Tan; Ryo Kimura; Nobuto Shibata; Heii Arai; M Ilyas Kamboh; Jonathan A Prince; Wolfgang Maier; Matthias Riemenschneider; Michael J Owen; Denise Harold; Paul Hollingworth; Elena Cellini; Sandro Sorbi; Benedetta Nacmias; Masatoshi Takeda; Margaret Pericak-Vance; Jonathan L Haines; Steven G Younkin; Julie Williams; Christine Van Broeckhoven; Lindsay Farrer; Peter St George-Hyslop; Richard Mayeux
Meta-analysis of the association between variants in SORL1 and Alzheimer disease.
Archives of neurology 2011;68(1):99-106.
2011: Y Liu; D H Blackwood; S Caesar; E J C de Geus; A Farmer; M A R Ferreira; I N Ferrier; C Fraser; K Gordon-Smith; E K Green; D Grozeva; H M Gurling; M L Hamshere; P Heutink; P A Holmans; W J Hoogendijk; J J Hottenga; L Jones; I R Jones; G Kirov; D Lin; P McGuffin; V Moskvina; W A Nolen; R H Perlis; D Posthuma; E M Scolnick; A B Smit; J H Smit; J W Smoller; D St Clair; R van Dyck; M Verhage; G Willemsen; A H Young; T Zandbelt; D I Boomsma; N Craddock; M C O'Donovan; Michael J Owen; B W J H Penninx; S Purcell; P Sklar; P F Sullivan
Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.
Molecular psychiatry 2011;16(1):2-4.
2010: Michael E Talkowski; Kathleen L McCann; Michael Chen; Lora McClain; Mikhil Bamne; Joel Wood; Kodavali V Chowdari; Annie Watson; Konasale M Prasad; George Kirov; Lyudmila Georgieva; Draga Toncheva; Hader A Mansour; David A Lewis; Michael J Owen; Michael O'Donovan; Panagiotis Papasaikas; Patrick Sullivan; Douglas Ruderfer; Jeffrey K Yao; Sherry Leonard; Pramod Thomas; Fabio Miyajima; John Quinn; A Javier Lopez; Vishwajit L Nimgaonkar
Fine-mapping reveals novel alternative splicing of the dopamine transporter.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(8):1434-47.
2010: Amy W Butler; Gerome Breen; Federica Tozzi; Nick Craddock; Mike Gill; Ania Korszun; Wolfgang Maier; Lefkos T Middleton; Ole Mors; Michael J Owen; Julia Perry; Martin Preisig; John P Rice; Marcella Rietschel; Lisa Jones; Anne E Farmer; Cathryn M Lewis; Peter McGuffin
A genomewide linkage study on suicidality in major depressive disorder confirms evidence for linkage to 2p12.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(8):1465-73.
2010: Sarah Dwyer; Hywel Williams; Peter Holmans; Valentina Moskvina; Nick Craddock; Michael J Owen; Michael C O'Donovan
No evidence that rare coding variants in ZNF804A confer risk of schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(8):1411-6.
2010: Kate Langley; Jessica Heron; Michael C O'Donovan; Michael J Owen; Anita Thapar
Genotype link with extreme antisocial behavior: the contribution of cognitive pathways.
Archives of general psychiatry 2010;67(12):1317-23.
2010: L S Carroll; Nigel M Williams; Valentina Moskvina; E Russell; Nadine Norton; Hywel J Williams; Tim Peirce; Lyudmila Georgieva; Sarah Dwyer; Detelina Grozeva; E Greene; Anne Farmer; Peter McGuffin; Derek W Morris; Aiden Corvin; Michael Gill; Dan Rujescu; Pak Sham; Peter Holmans; Ian Jones; George Kirov; Nick Craddock; Michael C O'Donovan; Michael J Owen
Evidence for rare and common genetic risk variants for schizophrenia at protein kinase C, alpha.
Molecular psychiatry 2010;15(11):1101-11.
2010: Nigel M Williams; Irina Zaharieva; Andrew Martin; Kate Langley; Kiran Mantripragada; Ragnheidur Fossdal; Hreinn Stefansson; Kari Stefansson; Pall Magnusson; Olafur O Gudmundsson; Omar Gustafsson; Peter Holmans; Michael J Owen; Michael O'Donovan; Anita Thapar
Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis.
Lancet 2010;376(9750):1401-8.
2010: Elaine K Green; Detelina Grozeva; Valentina Moskvina; Marian Hamshere; Ian R Jones; Lisa Jones; Liz Forty; Sian Caesar; Katherine Gordon-Smith; Christine Fraser; Ellie Russell; David St Clair; Allan H Young; Nicol Ferrier; Anne Farmer; Peter McGuffin; Peter Holmans; Michael J Owen; Michael C O'Donovan; Nick Craddock
Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(7):1347-9.
2010: Sarah Cohen-Woods; Ian Craig; Darya Gaysina; Joanna Gray; Cerisse Gunasinghe; Nick Craddock; Amanda Elkin; Lisa Jones; James Kennedy; Nicole King; Ania Korszun; Jo Knight; Michael J Owen; Sagar Parikh; John Strauss; Abram Sterne; Federica Tozzi; Julia Perry; Pierandrea Muglia; John Vincent; Peter McGuffin; Anne Farmer
The Bipolar Association Case-Control Study (BACCS) and meta-analysis: No association with the 5,10-Methylenetetrahydrofolate reductase gene and bipolar disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(7):1298-304.
2010: Shabnam Baig; Sally A Joseph; Hannah Tayler; Richard Abraham; Michael J Owen; Julie Williams; Patrick G Kehoe; Seth Love
Distribution and expression of picalm in Alzheimer disease.
Journal of neuropathology and experimental neurology 2010;69(10):1071-7.
2010: Elaine K Green; Detelina Grozeva; Ian Jones; Lesley Jones; George Kirov; Sian Caesar; Katherine Gordon-Smith; C Fraser; Liz Forty; E Russell; Marian Hamshere; Valentina Moskvina; Ivan Nikolov; Anne Farmer; Peter McGuffin; Peter Holmans; Michael J Owen; Michael C O'Donovan; Nick Craddock
The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia.
Molecular psychiatry 2010;15(10):1016-22.
2010: Carlos Cruchaga; John S K Kauwe; Kevin Mayo; Noah Spiegel; Sarah Bertelsen; Petra Nowotny; Aarti R Shah; Richard Abraham; Paul Hollingworth; Denise Harold; Michael J Owen; Julie Williams; Simon Lovestone; Elaine R Peskind; Ge Li; James B Leverenz; Douglas Galasko; John C Morris; Anne M Fagan; David M Holtzman; Alison Goate
SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease.
PLoS genetics 2010;6(9):.
2010: Stanley Zammit; Michael J Owen; Glyn Lewis
Misconceptions about gene-environment interactions in psychiatry.
Evidence-based mental health 2010;13(3):65-8.
2010: Cathryn M Lewis; Mandy Y Ng; Amy W Butler; Sarah Cohen-Woods; Rudolf Uher; Katrina Pirlo; Michael E Weale; Alexandra Schosser; Ursula M Paredes; Margarita Rivera; Nicholas Craddock; Michael J Owen; Lisa Jones; Ian Jones; Ania Korszun; Katherine J Aitchison; Jianxin Shi; John P Quinn; Alasdair Mackenzie; Peter Vollenweider; Gerard Waeber; Simon Heath; Mark Lathrop; Pierandrea Muglia; Michael R Barnes; John C Whittaker; Federica Tozzi; Florian Holsboer; Martin Preisig; Anne E Farmer; Gerome Breen; Ian W Craig; Peter McGuffin
Genome-wide association study of major recurrent depression in the U.K. population.
The American journal of psychiatry 2010;167(8):949-57.
2010: A Schosser; D Gaysina; S Cohen-Woods; P C Chow; L Martucci; N Craddock; A Farmer; Ania Korszun; C Gunasinghe; J Gray; L Jones; F Tozzi; J Perry; Pierandrea Muglia; Michael J Owen; I W Craig; Peter McGuffin
Association of DISC1 and TSNAX genes and affective disorders in the depression case-control (DeCC) and bipolar affective case-control (BACCS) studies.
Molecular psychiatry 2010;15(8):844-9.
2010: James T R Walters; Aiden Corvin; Michael J Owen; Hywel Williams; Milan Dragovic; Emma M Quinn; Róisín Judge; Daniel J Smith; Nadine Norton; Ina Giegling; Annette M Hartmann; Hans-Jürgen Möller; Pierandrea Muglia; Valentina Moskvina; Sarah Dwyer; Therese O'Donoghue; Bharti Morar; Matthew Cooper; David Chandler; Assen Jablensky; Michael Gill; Luba Kaladjieva; Derek W Morris; Michael C O'Donovan; Dan Rujescu; Gary Donohoe
Psychosis susceptibility gene ZNF804A and cognitive performance in schizophrenia.
Archives of general psychiatry 2010;67(7):692-700.
2010: Michael J Owen; Nick Craddock; Michael C O'Donovan
Suggestion of roles for both common and rare risk variants in genome-wide studies of schizophrenia.
Archives of general psychiatry 2010;67(7):667-73.
2010: Nick Craddock; Michael J Owen
Molecular genetics and the relationship between epilepsy and psychosis.
The British journal of psychiatry : the journal of mental science 2010;197(1):75-6; author reply 76.
2010: Masashi Ikeda; Nigel Williams; Hywel J Williams; Rhodri Smith; Stephen Monks; Michael J Owen; Kieran C Murphy; Michael C O'Donovan
Failure to confirm association between PIK4CA and psychosis in 22q11.2 deletion syndrome.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(4):980-2.
2010: John S K Kauwe; Sarah Bertelsen; Kevin Mayo; Carlos Cruchaga; Richard Abraham; Paul Hollingworth; D Harold; Michael J Owen; Julie Williams; Simon Lovestone; John C Morris; Alison Goate
Suggestive synergy between genetic variants in TF and HFE as risk factors for Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(4):955-9.
2010: Sudha Seshadri; Annette L Fitzpatrick; M Arfan Ikram; Anita L DeStefano; Vilmundur Gudnason; Merce Boada; Joshua C Bis; Albert Vernon Smith; Minerva M Carassquillo; Jean Charles Lambert; Denise Harold; Elisabeth M C Schrijvers; Reposo Ramirez-Lorca; Stephanie Debette; W T Longstreth; A Cecile J W Janssens; V Shane Pankratz; Jean-François Dartigues; Paul Hollingworth; Thor Aspelund; Isabel Hernandez; Alexa Beiser; Lewis H Kuller; Peter J Koudstaal; dennis dickson; Christophe Tzourio; Richard Abraham; Carmen Antunez; Yangchun Du; Jerome I Rotter; Yurii S Aulchenko; Tamara B Harris; Ronald C. Petersen; Claudine Berr; Michael J Owen; Jesus Lopez-Arrieta; Badri N Varadarajan; James T Becker; Fernando Rivadeneira; Michael A Nalls; Neill R Graff-Radford; Dominique Campion; Sanford Auerbach; Kenneth Rice; Albert Hofman; Palmi V Jonsson; Helena Schmidt; Mark Lathrop; Thomas H Mosley; Rhoda Au; Bruce M Psaty; Andre G Uitterlinden; Lindsay Farrer; Thomas Lumley; Agustin Ruiz; Julie Williams; Philippe Amouyel; Steve G Younkin; Philip A Wolf; Lenore J Launer; Oscar L Lopez; Cornelia M van Duijn; Monique Breteler
Genome-wide analysis of genetic loci associated with Alzheimer disease.
JAMA : the journal of the American Medical Association 2010;303(18):1832-40.
2010: Derek J Blake; Marc Forrest; Ria M Chapman; Caroline L Tinsley; Michael C O'Donovan; Michael J Owen
TCF4, schizophrenia, and Pitt-Hopkins Syndrome.
Schizophrenia bulletin 2010;36(3):443-7.
2010: Sarah Dwyer; L Carroll; Kiran K Mantripragada; Michael J Owen; Michael C O'Donovan; Nigel M Williams
Mutation screening of the DTNBP1 exonic sequence in 669 schizophrenics and 710 controls using high-resolution melting analysis.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(3):766-74.
2010: Detelina Grozeva; George Kirov; Dobril Ivanov; Ian Richard Jones; Lisa Jones; Elaine K Green; David M St Clair; Allan H Young; Nicol Ferrier; Anne E Farmer; Peter McGuffin; Peter Holmans; Michael J Owen; Michael C O'Donovan; Nick Craddock
Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia.
Archives of general psychiatry 2010;67(4):318-27.
2010: Andrés Ingason; Ina Giegling; Sven Cichon; Thomas Hansen; Henrik B Rasmussen; Jimmi Nielsen; Gesche Jürgens; Pierandrea Muglia; Annette M Hartmann; Eric Strengman; Catalina Vasilescu; Thomas W Mühleisen; Srdjan Djurovic; Ingrid Melle; Bernard Lerer; Hans-Jürgen Möller; Clyde Francks; Olli P H Pietiläinen; Jouko Lonnqvist; Jaana Suvisaari; Annamari Tuulio-Henriksson; Muriel Walshe; Evangelos Vassos; Marta Di Forti; Robin Murray; Chiara Bonetto; Sarah Tosato; Rita M Cantor; Marcella Rietschel; Nick Craddock; Michael J Owen; Leena Peltonen; Ole A Andreassen; Markus M Nöthen; David St Clair; Roel A Ophoff; Michael C O'Donovan; David A Collier; Thomas Werge; Dan Rujescu
A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia.
Human molecular genetics 2010;19(7):1379-86.
2010: Kate Langley; Tom Fowler; Tamsin Ford; Ajay K Thapar; Marianne B M van den Bree; Gordon Harold; Michael J Owen; Michael C O'Donovan; Anita Thapar
Adolescent clinical outcomes for young people with attention-deficit hyperactivity disorder.
The British journal of psychiatry : the journal of mental science 2010;196(3):235-40.
2010: Nick Craddock; Michael J Owen
The Kraepelinian dichotomy - going, going... but still not gone.
The British journal of psychiatry : the journal of mental science 2010;196(2):92-5.
2010: Masashi Ikeda; Branko Aleksic; George Kirov; Yoko Kinoshita; Yoshio Yamanouchi; Tsuyoshi Kitajima; Kunihiro Kawashima; Tomo Okochi; Taro Kishi; Irina Zaharieva; Michael J Owen; Michael C O'Donovan; Norio Ozaki; Nakao Iwata
Copy number variation in schizophrenia in the Japanese population.
Biological psychiatry 2010;67(3):283-6.
2010: Masashi Ikeda; Yasuyuki Tomita; Akihiro Mouri; Minori Koga; Tomo Okochi; Reiji Yoshimura; Yoshio Yamanouchi; Yoko Kinoshita; Ryota Hashimoto; Hywel J Williams; Masatoshi Takeda; Jun Nakamura; Toshitaka Nabeshima; Michael J Owen; Michael C O'Donovan; Hiroyuki Honda; Tadao Arinami; Norio Ozaki; Nakao Iwata
Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches.
Biological psychiatry 2010;67(3):263-9.
2010: Nick Craddock; Lesley Jones; I R Jones; George Kirov; Elaine K Green; Detelina Grozeva; Valentina Moskvina; Ivan Nikolov; Marian Hamshere; D Vukcevic; Sian Caesar; Katherine Gordon-Smith; C Fraser; E Russell; Nadine Norton; Gerome Breen; D St Clair; David A Collier; A H Young; Ian Nicol Ferrier; Anne Farmer; Peter McGuffin; Peter Holmans; P Donnelly; Michael J Owen; Michael C O'Donovan
Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.
Molecular psychiatry 2010;15(2):146-53.
2010: A Schosser; S Cohen-Woods; D Gaysina; P C Chow; L Martucci; Anne Farmer; Ania Korszun; C Gunashinghe; J Gray; L Jones; N Craddock; Michael J Owen; Ian W Craig; Peter McGuffin
NRG1 gene in recurrent major depression: no association in a large-scale case-control association study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(1):141-7.
2010: Lesley Jones; Peter A Holmans; Marian L Hamshere; Denise Harold; Valentina Moskvina; Dobril Ivanov; Andrew Pocklington; Richard Abraham; Paul Hollingworth; Rebecca Sims; Amy Gerrish; Jaspreet Singh Pahwa; Nicola Jones; Alexandra Stretton; Angharad R Morgan; Simon Lovestone; John Powell; Petroula Proitsi; Michelle K Lupton; Carol Brayne; David C Rubinsztein; Michael Gill; Brian Lawlor; Aoibhinn Lynch; Kevin Morgan; Kristelle S Brown; Peter A Passmore; David Craig; Bernadette McGuinness; Stephen Todd; Clive Holmes; David Mann; A David Smith; Seth Love; Patrick G Kehoe; Simon Mead; Nick C Fox; Martin N Rossor; John Collinge; Wolfgang Maier; Frank Jessen; Britta Schürmann; Reinhard Heun; Heike Kölsch; Hendrik van den Bussche; Isabella Heuser; Oliver Peters; Johannes Kornhuber; Jens Wiltfang; Martin Dichgans; Lutz Frölich; Harald Hampel; Michael Hüll; Dan Rujescu; Alison Goate; John S K Kauwe; Carlos Cruchaga; Petra Nowotny; John C Morris; Kevin Mayo; Gill Livingston; Nicholas J Bass; Hugh Gurling; Andrew McQuillin; Rhian Gwilliam; Panos Deloukas; Ammar Al-Chalabi; Christopher E Shaw; Andrew Singleton; Rita Guerreiro; Thomas W Mühleisen; Markus M Nöthen; Susanne Moebus; Karl-Heinz Jöckel; Norman Klopp; H-Erich Wichmann; Eckhard Rüther; Minerva M Carrasquillo; V Shane Pankratz; Steven G Younkin; John Hardy; Michael C O'Donovan; Michael J Owen; Julie Williams
Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.
PloS one 2010;5(11):e13950.
2010: Michelle K Lupton; Daniel Stahl; Nicola Archer; Catherine Foy; Michaela Poppe; Simon Lovestone; Paul Hollingworth; Julie Williams; Michael J Owen; Kimberley Dowzell; Richard Abraham; Rebecca Sims; Carol Brayne; David C Rubinsztein; Michael Gill; Brian A Lawlor; Aoibhinn Lynch; John F Powell
Education, occupation and retirement age effects on the age of onset of Alzheimer's disease.
International journal of geriatric psychiatry 2010;25(1):30-6.
2009: Richard Abraham; Rebecca Sims; Liam Carroll; Paul Hollingworth; Michael C O'Donovan; Julie Williams; Michael J Owen
An association study of common variation at the MAPT locus with late-onset Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(8):1152-5.
2009: Elaine K Green; Detelina Grozeva; Rachel Raybould; Gareth P Elvidge; Stuart Macgregor; Ian Craig; Anne Farmer; Peter McGuffin; Liz Forty; Lisa Jones; Ian Jones; Michael C O'Donovan; Michael J Owen; George Kirov; Nick Craddock
P2RX7: A bipolar and unipolar disorder candidate susceptibility gene?
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(8):1063-9.
2009: Tom Fowler; Kate Langley; Frances Rice; Marianne B M van den Bree; Kenny Ross; Lawrence S Wilkinson; Michael J Owen; Michael C O'Donovan; Anita Thapar
Psychopathy trait scores in adolescents with childhood ADHD: the contribution of genotypes affecting MAOA, 5HTT and COMT activity.
Psychiatric genetics 2009;19(6):312-9.
2009: Shane E McCarthy; Vladimir Makarov; George Kirov; Anjene M Addington; Jon McClellan; Seungtai Yoon; Diana O Perkins; Diane E Dickel; Mary Kusenda; Olga Krastoshevsky; Verena Krause; Ravinesh A Kumar; Detelina Grozeva; Dheeraj Malhotra; Tom Walsh; Elaine H Zackai; Paige Kaplan; Jaya Ganesh; Ian D Krantz; Nancy B Spinner; Patricia Roccanova; Abhishek Bhandari; Kevin Pavon; B Lakshmi; Anthony Leotta; Jude Kendall; Yoon-Ha Lee; Vladimir Vacic; Sydney Gary; Lilia M Iakoucheva; Timothy J Crow; Susan L Christian; Jeffrey A Lieberman; Thomas Stroup; Terho Lehtimäki; Kaija Puura; Chad Haldeman-Englert; Justin Pearl; Meredith Goodell; Virginia L Willour; Pamela Derosse; Jo Steele; Layla Kassem; Jessica Wolff; Nisha Chitkara; Francis McMajon; Anil Malhotra; James B Potash; Thomas G. Schulze; Markus M Nöthen; Sven Cichon; Marcella Rietschel; Ellen Leibenluft; Vlad Kustanovich; Clara M Lajonchere; James S Sutcliffe; David Skuse; Michael Gill; Louise Gallagher; Nancy R Mendell; Nick Craddock; Michael J Owen; Michael C O'Donovan; Tamim H Shaikh; Ezra Susser; Lynn E Delisi; Patrick F Sullivan; Curtis K Deutsch; Judith Rapoport; Deborah Levy; Mary-Claire King; Jonathan Sebat
Microduplications of 16p11.2 are associated with schizophrenia.
Nature genetics 2009;41(11):1223-7.
2009: L S Carroll; K Kendall; Michael C O'Donovan; Michael J Owen; Nigel M Williams
Evidence that putative ADHD low risk alleles at SNAP25 may increase the risk of schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(7):893-9.
2009: Gary Donohoe; James Walters; Derek W Morris; Emma M Quinn; Róisín Judge; Nadine Norton; Ina Giegling; Annette M Hartmann; Hans-Jürgen Möller; Pierandrea Muglia; Hywel Williams; Valentina Moskvina; Rosemary Peel; Therese O'Donoghue; Michael J Owen; Michael C O'Donovan; Michael Gill; Dan Rujescu; Aiden Corvin
Influence of NOS1 on verbal intelligence and working memory in both patients with schizophrenia and healthy control subjects.
Archives of general psychiatry 2009;66(10):1045-54.
2009: Denise Harold; Richard Abraham; Paul Hollingworth; Rebecca Sims; Amy Gerrish; Marian L Hamshere; Jaspreet Singh Pahwa; Valentina Moskvina; Kimberley Dowzell; Amy Williams; Nicola Jones; Charlene Thomas; Alexandra Stretton; Angharad R Morgan; Simon Lovestone; John Powell; Petroula Proitsi; Michelle K Lupton; Carol Brayne; David C Rubinsztein; Michael Gill; Brian Lawlor; Aoibhinn Lynch; Kevin Morgan; Kristelle S Brown; Peter A Passmore; David Craig; Bernadette McGuinness; Stephen Todd; Clive Holmes; D M A Mann; A David Smith; Seth Love; Patrick G Kehoe; John Hardy; Simon Mead; Nick C Fox; Martin N Rossor; John Collinge; Wolfgang Maier; Frank Jessen; Britta Schürmann; Hendrik van den Bussche; Isabella Heuser; Johannes Kornhuber; Jens Wiltfang; Martin Dichgans; Lutz Froelich; Harald Hampel; Michael Hüll; Dan Rujescu; Alison Goate; John S K Kauwe; Carlos Cruchaga; Petra Nowotny; John C Morris; Kevin Mayo; Kristel Sleegers; Karolien Bettens; Sebastiaan Engelborghs; Peter P De Deyn; Christine Van Broeckhoven; Gillian Livingston; Nicholas J Bass; Hugh Gurling; Andrew McQuillin; Rhian Gwilliam; Panagiotis Deloukas; Ammar Al-Chalabi; Christopher Shaw; Magda Tsolaki; Andrew Singleton; Rita Guerreiro; Thomas W Mühleisen; Markus M Nöthen; Susanne Moebus; Karl-Heinz Jöckel; Norman Klopp; H-Erich Wichmann; Minerva M Carrasquillo; V Shane Pankratz; Steven G Younkin; Peter A Holmans; Michael O'Donovan; Michael J Owen; Julie Williams
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
Nature genetics 2009;41(10):1088-93.
2009: Jesse B G Hayesmoore; Nicholas J Bray; William C Cross; Michael J Owen; Michael C O'Donovan; Huw R Morris
The effect of age and the H1c MAPT haplotype on MAPT expression in human brain.
Neurobiology of aging 2009;30(10):1652-6.
2009: R Sims; Paul Hollingworth; Valentina Moskvina; K Dowzell; Michael C O'Donovan; John Powell; Simon Lovestone; Carol Brayne; David C Rubinsztein; Michael J Owen; Julie Williams; Richard Abraham
Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease.
Neuroscience letters 2009;461(1):54-9.
2009: Marian L Hamshere; Thomas G. Schulze; Johannes Schumacher; Aiden Corvin; Michael J Owen; Rami Abou Jamra; Peter Propping; Wolfgang Maier; Guillermo Orozco y Diaz; Fermin Mayoral; Fabio Rivas; Ian Jones; Lisa Jones; George Kirov; Michael Gill; Peter A Holmans; Markus M Nöthen; Sven Cichon; Marcella Rietschel; Nick Craddock
Mood-incongruent psychosis in bipolar disorder: conditional linkage analysis shows genome-wide suggestive linkage at 1q32.3, 7p13 and 20q13.31.
Bipolar disorders 2009;11(6):610-20.
2009: George Kirov; Dan Rujescu; Andres Ingason; David A Collier; Michael C O'Donovan; Michael J Owen
Neurexin 1 (NRXN1) deletions in schizophrenia.
Schizophrenia bulletin 2009;35(5):851-4.
2009: Adelina Yosifova; Taisei Mushiroda; Drozdstoi Stoianov; Radoslava Vazharova; Ivanka Dimova; Sena Karachanak; Irina Zaharieva; vihra milanova; Nadejda Madjirova; Ivan Gerdjikov; Todor Tolev; Stoyanka Velkova; George Kirov; Michael J Owen; Michael C O'Donovan; Draga Toncheva; Yusuke Nakamura
Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.
Journal of affective disorders 2009;117(1-2):87-97.
2009: M Y M Ng; D F Levinson; S V Faraone; B K Suarez; L E DeLisi; T Arinami; B Riley; T Paunio; Ann E Pulver; P A Holmans; Michael Escamilla; D B Wildenauer; N M Williams; C Laurent; B J Mowry; L M Brzustowicz; M Maziade; P Sklar; D L Garver; G R Abecasis; B Lerer; MARGARET D FALLIN; H M D Gurling; P V Gejman; E Lindholm; H W Moises; W Byerley; E M Wijsman; P Forabosco; M T Tsuang; H-G Hwu; Y Okazaki; K S Kendler; B Wormley; A Fanous; D Walsh; Francis Anthony O'Neill; L Peltonen; Gerald Nestadt; V K Lasseter; Kung-Yee Liang; G M Papadimitriou; D G Dikeos; S G Schwab; Michael J Owen; M C O'Donovan; Nadine Norton; E Hare; H Raventos; H Nicolini; M Albus; W Maier; V L Nimgaonkar; L Terenius; J Mallet; M Jay; S Godard; D Nertney; M Alexander; R R Crowe; Jeremy Silverman; A S Bassett; M-A Roy; C Mérette; C N Pato; M T Pato; J Louw Roos; Y Kohn; D Amann-Zalcenstein; G Kalsi; A McQuillin; D Curtis; J Brynjolfson; T Sigmundsson; H Petursson; A R Sanders; J Duan; E Jazin; M Myles-Worsley; Maria Karayiorgou; C M Lewis
Meta-analysis of 32 genome-wide linkage studies of schizophrenia.
Molecular psychiatry 2009;14(8):774-85.
2009: H A Ball; Z Samaan; Shyama Brewster; Nick Craddock; Michael Gill; Ania Korszun; Wolfgang Maier; Lefkos T Middleton; Ole Mors; Michael J Owen; J Perry; Martin Preisig; J Rice; Marcella Rietschel; L Jones; Ian Jones; A E Farmer; Peter McGuffin
Depression, migraine with aura and migraine without aura: their familiality and interrelatedness.
Cephalalgia : an international journal of headache 2009;29(8):848-54.
2009: P A Holmans; B Riley; Ann E Pulver; Michael J Owen; D B Wildenauer; P V Gejman; B J Mowry; C Laurent; K S Kendler; Gerald Nestadt; N M Williams; S G Schwab; A R Sanders; D Nertney; J Mallet; B Wormley; V K Lasseter; M C O'Donovan; J Duan; M Albus; M Alexander; S Godard; R Ribble; Kung-Yee Liang; Nadine Norton; W Maier; G Papadimitriou; D Walsh; M Jay; A O'Neill; F B Lerer; D Dikeos; R R Crowe; Jeremy Silverman; D F Levinson
Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms.
Molecular psychiatry 2009;14(8):786-95.
2009: George Kirov; I Zaharieva; Lyudmila Georgieva; Valentina Moskvina; Ivan Nikolov; Sven Cichon; A Hillmer; D Toncheva; Michael J Owen; Michael C O'Donovan
A genome-wide association study in 574 schizophrenia trios using DNA pooling.
Molecular psychiatry 2009;14(8):796-803.
2009: Marian Hamshere; Elaine K Green; I R Jones; Lesley Jones; Valentina Moskvina; George Kirov; Detelina Grozeva; Ivan Nikolov; D Vukcevic; Sian Caesar; Katherine Gordon-Smith; C Fraser; E Russell; Gerome Breen; D St Clair; D A Collier; A H Young; Ian Nicol Ferrier; Anne Farmer; Peter McGuffin; Peter Holmans; Michael J Owen; Michael C O'Donovan; Nick Craddock
Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept.
The British journal of psychiatry : the journal of mental science 2009;195(1):23-9.
2009: Michael C O'Donovan; Michael J Owen
Genetics and the brain: many pathways to enlightenment.
Human genetics 2009;126(1):1-2.
2009: Peter Holmans; Elaine K Green; Jaspreet Singh Pahwa; Manuel A R Ferreira; Shaun M Purcell; Pamela Sklar; Michael J Owen; Michael C O'Donovan; Nick Craddock
Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder.
American journal of human genetics 2009;85(1):13-24.
2009: Michael C O'Donovan; Nick J Craddock; Michael J Owen
Genetics of psychosis; insights from views across the genome.
Human genetics 2009;126(1):3-12.
2009: Michael E Talkowski; Lora McClain; Trina Allen; L Dianne Bradford; Monica Calkins; Neil Edwards; Lyudmila Georgieva; Rodney Go; Ruben Gur; Raquel Gur; George Kirov; Kodavali V Chowdari; Joseph Kwentus; Paul Lyons; Hader A Mansour; Joseph McEvoy; Michael C O'Donovan; Judith O'Jile; Michael J Owen; Alberto B Santos; Robert Savage; Draga Toncheva; Gerard Vockley; Joel Wood; Bernie Devlin; Vishwajit L Nimgaonkar
Convergent patterns of association between phenylalanine hydroxylase variants and schizophrenia in four independent samples.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(4):560-9.
2009: Michael J Owen; Hywel J Williams; Michael C O'Donovan
Schizophrenia genetics: advancing on two fronts.
Current opinion in genetics & development 2009;19(3):266-70.
2009: Nick Craddock; M C O'Donovan; Michael J Owen
Psychosis genetics: modeling the relationship between schizophrenia, bipolar disorder, and mixed (or "schizoaffective") psychoses.
Schizophrenia bulletin 2009;35(3):482-90.
2009: George Kirov; Detelina Grozeva; Nadine Norton; Dobril Ivanov; Kiran K Mantripragada; Peter Holmans; Nick Craddock; Michael J Owen; Michael C O'Donovan
Support for the involvement of large copy number variants in the pathogenesis of schizophrenia.
Human molecular genetics 2009;18(8):1497-503.
2009: Sarah Cohen-Woods; Daria Gaysina; Nick Craddock; Anne Farmer; Joanna Gray; Cerisse Gunasinghe; Farzana Hoda; Lisa Jones; Jo Knight; Ania Korszun; Michael J Owen; Abram Sterne; Ian W Craig; Peter McGuffin
Depression Case Control (DeCC) Study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder.
Human molecular genetics 2009;18(8):1504-9.
2009: Zainab Samaan; Anne Farmer; Nick Craddock; Lisa Jones; Ania Korszun; Michael J Owen; Peter McGuffin
Migraine in recurrent depression: case-control study.
The British journal of psychiatry : the journal of mental science 2009;194(4):350-4.
2009: Rayna Azuma; Eileen Daly; Linda E Campbell; Angela F Stevens; Quinton Deeley; Vincent Giampietro; Michael J Brammer; Beate Glaser; Fiona Z Ambery; Robin G Morris; Steven C R Williams; Michael J Owen; Declan G M Murphy; Kieran C Murphy
Visuospatial working memory in children and adolescents with 22q11.2 deletion syndrome; an fMRI study.
Journal of neurodevelopmental disorders 2009;1(1):46-60.
2009: V Moskvina; Nick Craddock; Peter Holmans; Ivan Nikolov; J S Pahwa; Elaine Green; Michael J Owen; Michael C O'Donovan
Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk.
Molecular psychiatry 2009;14(3):252-60.
2009: Elitza T Betcheva; Taisei Mushiroda; Atsushi Takahashi; Michiaki Kubo; Sena K Karachanak; Irina T Zaharieva; Radoslava V Vazharova; Ivanka I Dimova; Vihra K Milanova; Todor Tolev; George Kirov; Michael J Owen; Michael C O'Donovan; Naoyuki Kamatani; Yusuke Nakamura; Draga I Toncheva
Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population.
Journal of human genetics 2009;54(2):98-107.
2009: Michael J Owen; Nick Craddock
Diagnosis of functional psychoses: time to face the future.
Lancet 2009;373(9659):190-1.
2009: A R Morgan; Paul Hollingworth; Richard Abraham; Simon Lovestone; Carol Brayne; David C Rubinsztein; A Lynch; Brian A Lawlor; Michael Gill; Michael C O'Donovan; Michael J Owen; Julie Williams
Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(1):61-4.
2009: Liam S Carroll; Michael J Owen
Genetic overlap between autism, schizophrenia and bipolar disorder.
Genome medicine 2009;1(10):102.
2009: Yang Liu; Gang Chen; Nadine Norton; Wenmin Liu; Haining Zhu; Peng Zhou; Meng Luan; Shulin Yang; Xing Chen; Liam Carroll; Nigel M Williams; Michael C O'Donovan; George Kirov; Michael J Owen
Whole genome association study in a homogenous population in Shandong peninsula of China reveals JARID2 as a susceptibility gene for schizophrenia.
Journal of biomedicine & biotechnology 2009;2009():536918.
2009: Hywel J Williams; Michael J Owen; Michael C O'Donovan
Schizophrenia genetics: new insights from new approaches.
British medical bulletin 2009;91():61-74.
2009: Hywel J Williams; Michael J Owen; Michael C O'Donovan
New findings from genetic association studies of schizophrenia.
Journal of human genetics 2009;54(1):9-14.
2009: Tom Fowler; Kate Langley; Frances Rice; Naureen Whittinger; Kenny Ross; Stephanie van Goozen; Michael J Owen; Michael C O'Donovan; Marianne B M van den Bree; Anita Thapar
Psychopathy traits in adolescents with childhood attention-deficit hyperactivity disorder.
The British journal of psychiatry : the journal of mental science 2009;194(1):62-7.
2009: M C O'Donovan; N Craddock; Michael J Owen
Strong evidence for multiple psychosis susceptibility genes - a rejoinder to Crow.
Psychological medicine 2009;39(1):170-1.
2009: A Gerrish; Hywel Williams; Valentina Moskvina; Michael J Owen; Michael C O'Donovan; Nigel M Williams
An examination of MUTED as a schizophrenia susceptibility gene.
Schizophrenia research 2009;107(1):110-1.
2009: M C O'Donovan; Nadine Norton; H Williams; T Peirce; V Moskvina; I Nikolov; M Hamshere; L Carroll; L Georgieva; S Dwyer; P Holmans; J L Marchini; C C A Spencer; B Howie; H-T Leung; I Giegling; A M Hartmann; H-J Möller; D W Morris; Y Shi; G Feng; P Hoffmann; P Propping; C Vasilescu; W Maier; M Rietschel; S Zammit; J Schumacher; E M Quinn; Thomas G. Schulze; N Iwata; M Ikeda; A Darvasi; S Shifman; L He; J Duan; A R Sanders; D F Levinson; R Adolfsson; U Osby; L Terenius; E G Jönsson; S Cichon; M M Nöthen; M Gill; A P Corvin; D Rujescu; P V Gejman; G Kirov; N Craddock; N M Williams; Michael J Owen
Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2.
Molecular psychiatry 2009;14(1):30-6.
2009: Kate Langley; Tom Fowler; Deborah L Grady; Robert K Moyzis; Peter A Holmans; Marianne B M van den Bree; Michael J Owen; Michael C O'Donovan; Anita Thapar
Molecular genetic contribution to the developmental course of attention-deficit hyperactivity disorder.
European child & adolescent psychiatry 2009;18(1):26-32.
2008: Michael C O'Donovan; George Kirov; Michael J Owen
Phenotypic variations on the theme of CNVs.
Nature genetics 2008;40(12):1392-3.
2008: Michael C O'Donovan; Nick Craddock; Michael J Owen
Schizophrenia: complex genetics, not fairy tales.
Psychological medicine 2008;38(12):1697-9; discussion 1818-20.
2008: J B G Hayesmoore; Nicholas J Bray; Michael J Owen; Michael C O'Donovan
DISC1 mRNA expression is not influenced by common Cis-acting regulatory polymorphisms or imprinting.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(7):1065-9.
2008: John B J Kwok; Clement T Loy; Gillian Hamilton; Edmond Lau; Marianne Hallupp; Julie Williams; Michael J Owen; G Anthony Broe; Nelson Tang; Linda Lam; John F Powell; Simon Lovestone; Peter R Schofield
Glycogen synthase kinase-3beta and tau genes interact in Alzheimer's disease.
Annals of neurology 2008;64(4):446-54.
2008: Nigel M Williams; Hywel Williams; Elisa Majounie; Nadine Norton; Beate Glaser; Huw R Morris; Michael J Owen; Michael C O'Donovan
Analysis of copy number variation using quantitative interspecies competitive PCR.
Nucleic acids research 2008;36(17):e112.
2008: D Gaysina; S Cohen; N Craddock; A Farmer; F Hoda; A Korszun; Michael J Owen; Ian W Craig; Peter McGuffin
No association with the 5,10-methylenetetrahydrofolate reductase gene and major depressive disorder: results of the depression case control (DeCC) study and a meta-analysis.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(6):699-706.
2008: A R Morgan; Gillian Hamilton; Darko Turic; Luke Jehu; Denise Harold; Richard Abraham; Paul Hollingworth; Valentina Moskvina; Carol Brayne; David C Rubinsztein; A Lynch; Brian A Lawlor; Michael Gill; Michael O'Donovan; John Powell; Simon Lovestone; Julie Williams; Michael J Owen
Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(6):727-31.
2008: Elin S Blom; Peter Holmans; Sampath Arepalli; Omanma Adighibe; Marian L Hamshere; Margaret Gatz; Nancy L Pedersen; A L Mina Bergem; Michael J Owen; Paul Hollingworth; Alison Goate; Julie Williams; Lars Lannfelt; John Hardy; Fabienne Wavrant-De Vrièze; Anna Glaser
Does APOE explain the linkage of Alzheimer's disease to chromosome 19q13?
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(6):778-83.
2008: Manuel A R Ferreira; Michael C O'Donovan; Yan A Meng; Ian R Jones; Douglas M Ruderfer; Lisa Jones; Jinbo Fan; George Kirov; Roy H Perlis; Elaine K Green; Jordan W Smoller; Detelina Grozeva; Jennifer Stone; Ivan Nikolov; Kimberly Chambert; Marian L Hamshere; Vishwajit L Nimgaonkar; Valentina Moskvina; Michael E Thase; Sian Caesar; Gary S Sachs; Jennifer Franklin; Katherine Gordon-Smith; Kristin G Ardlie; Stacey B Gabriel; Christine Fraser; Brendan Blumenstiel; Matthew Defelice; Gerome Breen; Michael Gill; Derek W Morris; Amanda Elkin; Walter J Muir; McGhee Kevin; Richard Williamson; Donald J MacIntyre; Alan W MacLean; Clair David St; Michelle Robinson; Margaret Van Beck; Ana C P Pereira; Radhika Kandaswamy; Andrew McQuillin; David A Collier; Nicholas J Bass; Allan H Young; Jacob Lawrence; Ian Nicol Ferrier; Adebayo Anjorin; Anne Farmer; David Curtis; Edward M Scolnick; Peter McGuffin; Mark J Daly; Aiden P Corvin; Peter A Holmans; Douglas H Blackwood; Hugh M Gurling; Michael J Owen; Shaun M Purcell; Pamela Sklar; Nick Craddock
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.
Nature genetics 2008;40(9):1056-8.
2008: Michael C O'Donovan; Nicholas Craddock; Nadine Norton; Hywel Williams; Timothy Peirce; Valentina Moskvina; Ivan Nikolov; Marian Hamshere; Liam Carroll; Lyudmila Georgieva; Sarah Dwyer; Peter Holmans; Jonathan L Marchini; Chris C A Spencer; Bryan Howie; Hin-Tak Leung; Annette M Hartmann; Hans-Jürgen Möller; Derek W Morris; Yongyong Shi; GuoYin Feng; Per Hoffmann; Peter Propping; Catalina Vasilescu; Wolfgang Maier; Marcella Rietschel; Stanley Zammit; Johannes Schumacher; Emma M Quinn; Thomas G. Schulze; Nigel M Williams; Ina Giegling; Nakao Iwata; Masashi Ikeda; Ariel Darvasi; Sagiv Shifman; Lin He; Jubao Duan; Alan R Sanders; Douglas F Levinson; Pablo V Gejman; Sven Cichon; Markus M Nöthen; Michael Gill; Aiden Corvin; Dan Rujescu; George Kirov; Michael J Owen; Nancy G Buccola; Bryan J Mowry; Robert Freedman; Farooq Amin; Donald W Black; Jeremy Silverman; William F Byerley; C Robert Cloninger
Identification of loci associated with schizophrenia by genome-wide association and follow-up.
Nature genetics 2008;40(9):1053-5.
2008: Lyudmila Georgieva; Albena Dimitrova; Dobril Ivanov; Ivan Nikolov; Nigel M Williams; Detelina Grozeva; Irina Zaharieva; Draga Toncheva; Michael J Owen; George Kirov; Michael C O'Donovan
Support for neuregulin 1 as a susceptibility gene for bipolar disorder and schizophrenia.
Biological psychiatry 2008;64(5):419-27.
2008: Nick Craddock; Danny Antebi; Mary-Jane Attenburrow; Anthony Bailey; Alan Carson; Phil Cowen; Bridget Craddock; John Eagles; Klaus P. Ebmeier; Anne Farmer; Seena Fazel; Nicol Ferrier; John Geddes; Guy Goodwin; Paul Harrison; Keith Hawton; Stephen Hunter; Robin Jacoby; Ian Jones; Paul Keedwell; Mike Kerr; Paul Mackin; Peter McGuffin; Donald J Macintyre; Pauline McConville; Deborah Mountain; Michael C O'Donovan; Michael J Owen; Femi Oyebode; Mary Louise Phillips; Jonathan Price; Prem Shah; Danny J Smith; James Walters; Peter Woodruff; Allan Young; Stan Zammit
Wake-up call for British psychiatry.
The British journal of psychiatry : the journal of mental science 2008;193(1):6-9.
2008: N Craddock; M C O'Donovan; Michael J Owen
Genome-wide association studies in psychiatry: lessons from early studies of non-psychiatric and psychiatric phenotypes.
Molecular psychiatry 2008;13(7):649-53.
2008: Anne Farmer; Ania Korszun; Michael J Owen; Nick Craddock; Lisa Jones; Ian Jones; Jo Gray; Richard J Williamson; Peter McGuffin
Medical disorders in people with recurrent depression.
The British journal of psychiatry : the journal of mental science 2008;192(5):351-5.
2008: Nicholas J Bray; Peter Holmans; Marianne B M van den Bree; Lesley Jones; Lyn A Elliston; Gareth Hughes; Alexander L Richards; Nigel M Williams; Nick Craddock; Michael J Owen; Michael C O'Donovan
Cis- and trans- loci influence expression of the schizophrenia susceptibility gene DTNBP1.
Human molecular genetics 2008;17(8):1169-74.
2008: Yonghong Li; Andrew Grupe; Charles Rowland; Peter Holmans; Ricardo Segurado; Richard Abraham; Lesley Jones; Joseph J Catanese; David Ross; Kevin Mayo; Maribel Martinez; Paul Hollingworth; Alison Goate; Nigel J Cairns; Brad A Racette; Joel S Perlmutter; Michael C O'Donovan; John C Morris; Carol Brayne; David C Rubinsztein; Simon Lovestone; Leon J Thal; Michael J Owen; Julie Williams
Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease.
Human molecular genetics 2008;17(5):759-67.
2008: Michael E Talkowski; George Kirov; Mikhil Bamne; Lyudmila Georgieva; Gonzalo Torres; Hader A Mansour; Kodavali V Chowdari; vihra milanova; Joel Wood; Lora McClain; Konasale Prasad; Brian H Shirts; Jianping Zhang; Michael C O'Donovan; Michael J Owen; Bernie Devlin; Vishwajit L Nimgaonkar
A network of dopaminergic gene variations implicated as risk factors for schizophrenia.
Human molecular genetics 2008;17(5):747-58.
2008: Nigel M Williams; Beate Glaser; Nadine Norton; Hywel Williams; Timothy Pierce; Valentina Moskvina; Stephen Monks; Jurgen Del-Favero; Dirk Goossens; Dan Rujescu; Ina Giegling; George Kirov; Nicholas Craddock; Kieran C Murphy; Michael C O'Donovan; Michael J Owen
Strong evidence that GNB1L is associated with schizophrenia.
Human molecular genetics 2008;17(4):555-66.
2008: Sagiv Shifman; Martina Johannesson; Michal Bronstein; Sam X Chen; David A Collier; Nicholas J Craddock; Kenneth S Kendler; Tao Li; Michael O'Donovan; Francis Anthony O'Neill; Michael J Owen; Dermot Walsh; Daniel R Weinberger; Cuie Sun; Jonathan Flint; Saurav Guha
Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women.
PLoS genetics 2008;4(2):e28.
2008: Avshalom Caspi; Kate Langley; Barry J Milne; Terrie E Moffitt; Michael O'Donovan; Michael J Owen; Monica Polo-Tomas; Richie Poulton; Michael Rutter; Alan Taylor; Benjamin Williams; Anita Thapar
A replicated molecular genetic basis for subtyping antisocial behavior in children with attention-deficit/hyperactivity disorder.
Archives of general psychiatry 2008;65(2):203-10.
2008: George Kirov; Gumus Gumus; Wei Chen; Nadine Norton; Lyudmila Georgieva; Murat Sari; Michael C O'Donovan; Fikret Erdogan; Michael J Owen; Hans-Hilger Ropers; Reinhard Ullmann
Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia.
Human molecular genetics 2008;17(3):458-65.
2008: Yonghong Li; Charles Rowland; Joseph J Catanese; John C Morris; Simon Lovestone; Michael C O'Donovan; Alison Goate; Michael J Owen; Julie Williams; Andrew Grupe
SORL1 variants and risk of late-onset Alzheimer's disease.
Neurobiology of disease 2008;29(2):293-6.
2008: Joseph Buxbaum; Lyudmila Georgieva; J J Young; C Plescia; Y Kajiwara; Y Jiang; Valentina Moskvina; Nadine Norton; Tim Peirce; Hywel Williams; Nick Craddock; L Carroll; Gabriel Corfas; Kenneth L Davis; Michael J Owen; Sheila Harroch; T Sakurai; Michael C O'Donovan
Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene.
Molecular psychiatry 2008;13(2):162-72.
2008: Kate Langley; Darko Turic; Frances Rice; Peter Holmans; Marianne B M van den Bree; Nick Craddock; Lindsey Kent; Michael J Owen; Michael C O'Donovan; Anita Thapar
Testing for gene x environment interaction effects in attention deficit hyperactivity disorder and associated antisocial behavior.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(1):49-53.
2008: Alexander L Richards; Peter Holmans; Michael C O'Donovan; Michael J Owen; Lesley Jones
A comparison of four clustering methods for brain expression microarray data.
BMC bioinformatics 2008;9():490.
2008: Richard Abraham; Valentina Moskvina; Rebecca Sims; Paul Hollingworth; Angharad Morgan; Lyudmila Georgieva; Kimberley Dowzell; Sven Cichon; Axel M Hillmer; Michael C O'Donovan; Julie Williams; Michael J Owen; George Kirov
A genome-wide association study for late-onset Alzheimer's disease using DNA pooling.
BMC medical genomics 2008;1():44.
2008: Irina Zaharieva; Lyudmila Georgieva; Ivan Nikolov; George Kirov; Michael J Owen; Michael C O'Donovan; Draga Toncheva
Association study in the 5q31-32 linkage region for schizophrenia using pooled DNA genotyping.
BMC psychiatry 2008;8():11.
2008: Hao Li; Sally Wetten; Li Li; Pamela L St Jean; Ruchi Upmanyu; Linda Surh; David Hosford; Michael R Barnes; James David Briley; Michael Borrie; Natalie Coletta; Richard Delisle; Daniella Dhalla; Margaret G Ehm; Howard H Feldman; Luis Fornazzari; S Gauthier; Neil Goodgame; Danilo Guzman; Sandra Hammond; Paul Hollingworth; Ging-Yuek Hsiung; Joan Johnson; Devon D Kelly; Ron Keren; Andrew Kertesz; Karen S King; Simon Lovestone; Inge Loy-English; Paul Matthews; Michael J Owen; Mary Plumpton; William Pryse-Phillips; Rab Prinjha; Jill C Richardson; Ann M Saunders; Andrew J Slater; Peter St George-Hyslop; Sandra W Stinnett; Jina Swartz; Rachel L Taylor; John Wherrett; Julie Williams; David P Yarnall; Rachel A Gibson; Michael C Irizarry; Lefkos T Middleton; Allen D Roses
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
Archives of neurology 2008;65(1):45-53.
2008: Valentina Moskvina; Anne Farmer; Ian Richard Jones; Shyama Brewster; François Ferrero; Michael Gill; Lisa Anne Jones; Wolfgang Maier; Ole Mors; Michael J Owen; Julia Perry; Martin Preisig; Marcella Rietschel; Peter McGuffin; Nick Craddock; Ania Korszun
Sex differences in symptom patterns of recurrent major depression in siblings.
Depression and anxiety 2008;25(6):527-34.
2008: Therese van Amelsvoort; Janneke Zinkstok; Martijn Figee; Eileen Daly; R Morris; Michael J Owen; Kieran C Murphy; Lieuwe de Haan; Don Linszen; B Glaser; Declan G M Murphy
Effects of a functional COMT polymorphism on brain anatomy and cognitive function in adults with velo-cardio-facial syndrome.
Psychological medicine 2008;38(1):89-100.
2007: Hywel J Williams; Nadine Norton; Tim Peirce; Sarah Dwyer; Nigel M Williams; Valentina Moskvina; Michael J Owen; Michael C O'Donovan
Association analysis of the glial cell line-derived neurotrophic factor (GDNF) gene in schizophrenia.
Schizophrenia research 2007;97(1-3):271-6.
2007: Anita Thapar; Kate Langley; Michael J Owen; Michael C O'Donovan
Advances in genetic findings on attention deficit hyperactivity disorder.
Psychological medicine 2007;37(12):1681-92.
2007: Marian Hamshere; Peter Holmans; Dimitrios Avramopoulos; Susan S Bassett; Deborah Blacker; Lars Bertram; Howard Wiener; Nan Rochberg; Rudolph E Tanzi; Amanda Myers; Fabienne Wavrant-De Vrièze; Rodney Go; Daniele Fallin; Simon Lovestone; John Hardy; Alison Goate; Michael O'Donovan; Julie Williams; Michael J Owen
Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease.
Human molecular genetics 2007;16(22):2703-12.
2007: Stanley Zammit; Gillian Spurlock; Hywel Williams; Nadine Norton; Nigel Williams; Michael C O'Donovan; Michael J Owen
Genotype effects of CHRNA7, CNR1 and COMT in schizophrenia: interactions with tobacco and cannabis use.
The British journal of psychiatry : the journal of mental science 2007;191():402-7.
2007: Paul R Burton; David G Clayton; Lon R Cardon; Nick Craddock; Panos Deloukas; Audrey Duncanson; Dominic P Kwiatkowski; Mark I McCarthy; Willem H Ouwehand; Nilesh J Samani; John A Todd; Peter Donnelly; Jeffrey C Barrett; Dan Davison; Doug Easton; David M Evans; Hin-Tak Leung; Jonathan L Marchini; Andrew P Morris; Chris C A Spencer; Martin D Tobin; Antony P Attwood; James P Boorman; Barbara Cant; Ursula Everson; Judith M Hussey; Jennifer D Jolley; Alexandra S Knight; Kerstin Koch; Elizabeth Meech; Sarah Nutland; Christopher V Prowse; Helen E Stevens; Niall C Taylor; Graham R Walters; Neil M Walker; Nicholas A Watkins; Thilo Winzer; Richard W Jones; Wendy L McArdle; Susan M Ring; David P Strachan; Marcus Pembrey; Gerome Breen; David St Clair; Sian Caesar; Katharine Gordon-Smith; Lisa Jones; Christine Fraser; Elaine K Green; Detelina Grozeva; Marian L Hamshere; Peter A Holmans; Ian R Jones; George Kirov; Valentina Moskivina; Ivan Nikolov; Michael C O'Donovan; Michael J Owen; David A Collier; Amanda Elkin; Anne Farmer; Richard Williamson; Peter McGuffin; Allan H Young; Ian Nicol Ferrier; Stephen G Ball; Anthony J Balmforth; Jennifer H Barrett; D Timothy Bishop; Mark M Iles; Azhar Maqbool; Nadira Yuldasheva; Alistair S Hall; Peter S Braund; Richard J Dixon; Massimo Mangino; Suzanne Stevens; John R Thompson; Francesca Bredin; Mark Tremelling; Miles Parkes; Hazel Drummond; Charles W Lees; Elaine R Nimmo; Jack Satsangi; Sheila A Fisher; Alastair Forbes; Cathryn M Lewis; Clive M Onnie; Natalie Prescott; Jeremy Sanderson; Christopher G Matthew; Jamie Barbour; M Khalid Mohiuddin; Catherine E Todhunter; John C Mansfield; Tariq Ahmad; Fraser R Cummings; Derek P Jewell; John Webster; Morris J Brown; Mark G Lathrop; John Connell; Anna Dominiczak; Carolina A Braga Marcano; Beverley Burke; Richard Dobson; Johannie Gungadoo; Kate L Lee; Patricia B Munroe; Stephen Newhouse; Abiodun Onipinla; chris wallace; Mingzhan Xue; Mark Caulfield; Martin Farrall; Anne Barton; Ian Bruce; Hannah Donovan; Steve Eyre; Paul D Gilbert; Samantha L Hilder; Anne M Hinks; Sally L John; Catherine Potter; Alan J Silman; Deborah Symmons; Wendy Thomson; Jane Worthington; David D Dunger; Barry Widmer; Timothy M Frayling; Rachel Freathy; Hana Lango; John R B Perry; Beverley M Shields; Michael Weedon; Andrew T Hattersley; Graham A Hitman; Mark Walker; Kate S Elliott; Christopher J Groves; Cecilia M Lindgren; Nigel W Rayner; Nicolas J Timpson; Eleftheria Zeggini; Melanie Newport; Giorgio Sirugo; Emily Lyons; Fredrik Vannberg; Adrian V S Hill; Linda A Bradbury; Claire Farrar; Jennifer J Pointon; Paul Wordsworth; Matthew A Brown; Jayne A Franklyn; Joanne M Heward; Matthew J Simmonds; Stephen C L Gough; Sheila Seal; Michael R Stratton; Nazneen Rahman; Maria Ban; An Goris; Stephen J Sawcer; Alastair Compston; David Conway; Muminatou Jallow; Melanie Newport; Giorgio Sirugo; Kirk A Rockett; Suzannah J Bumpstead; Amy Chaney; Kate Downes; Mohammed J R Ghori; Rhian Gwilliam; Sarah E Hunt; Michael Inouye; Andrew Keniry; Emma King; Ralph McGinnis; Simon Potter; Rathi Ravindrarajah; Pamela Whittaker; Claire Widden; David Withers; Niall J Cardin; Dan Davison; Teresa Ferreira; Joanne Pereira-Gale; Ingeleif B Hallgrimsdo'ttir; Bryan N Howie; Zhan Su; Yik Ying Teo; Damjan Vukcevic; David Bentley; Matthew A Brown; Alastair Compston; Martin Farrall; Alistair Hall; Andrew T Hattersley; Adrian V S Hill; Miles Parkes; Marcus E Pembrey; Michael R Stratton; Sarah L Mitchell; Paul R Newby; Oliver J Brand; Jackie Carr-Smith; Simon H S Pearce; R McGinnis; A Keniry; P Deloukas; John D Reveille; Xiaodong Zhou; Anne-Marie Sims; Alison Dowling; Jacqueline Taylor; Tracy Doan; John C Davis; Laurie Savage; Michael M Ward; Thomas L Learch; Michael H Weisman; Mathew Brown
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.
Nature genetics 2007;39(11):1329-37.
2007: Paul Hollingworth; Marian Hamshere; Peter Holmans; Michael C O'Donovan; Rebecca Sims; John Powell; Simon Lovestone; Amanda Myers; FW DeVrieze; John Hardy; Alison Goate; Michael J Owen; Julie Williams
Increased familial risk and genomewide significant linkage for Alzheimer's disease with psychosis.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(7):841-8.
2007: A R Morgan; Darko Turic; Luke Jehu; Gillian Hamilton; Paul Hollingworth; Valentina Moskvina; Lesley Jones; Simon Lovestone; Carol Brayne; David C Rubinsztein; Brian A Lawlor; Michael Gill; Michael C O'Donovan; Michael J Owen; Julie Williams
Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(6):762-70.
2007: Frances Rice; Allyson Lewis; Gordon Harold; Marianne B M van den Bree; Jacky Boivin; Dale F Hay; Michael J Owen; Anita Thapar
Agreement between maternal report and antenatal records for a range of pre and peri-natal factors: the influence of maternal and child characteristics.
Early human development 2007;83(8):497-504.
2007: Ian Jones; Marian Hamshere; Jeanne-Marrie Nangle; Philip Bennett; Elaine Green; Jessica Heron; Ricardo Segurado; David Lambert; Peter Holmans; Aiden Corvin; Michael J Owen; Lisa Jones; Michael Gill; Nick Craddock
Bipolar affective puerperal psychosis: genome-wide significant evidence for linkage to chromosome 16.
The American journal of psychiatry 2007;164(7):1099-104.
2007: Michael J Owen; Nick Craddock; Assen Jablensky
The genetic deconstruction of psychosis.
Schizophrenia bulletin 2007;33(4):905-11.
2007: Nadine Norton; Hywel J Williams; Sarah Dwyer; Liam Carroll; Tim Peirce; Valentina Moskvina; Ricardo Segurado; Ivan Nikolov; Nigel M Williams; Masashi Ikeda; Nakao Iwata; Michael J Owen; Michael C O'Donovan
Association analysis of AKT1 and schizophrenia in a UK case control sample.
Schizophrenia research 2007;93(1-3):58-65.
2007: Gillian Hamilton; Petra Proitsi; Luke Jehu; Angharad Morgan; Julie Williams; Michael C O'Donovan; Michael J Owen; John F Powell; Simon Lovestone
Candidate gene association study of insulin signaling genes and Alzheimer's disease: evidence for SOS2, PCK1, and PPARgamma as susceptibility loci.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(4):508-16.
2007: Denise Harold; Luke Jehu; Darko Turic; Paul Hollingworth; Pamela Moore; P Summerhayes; Valentina Moskvina; Catherine Foy; Nicola Archer; B A Hamilton; Simon Lovestone; John Powell; Carol Brayne; David C Rubinsztein; Lesley Jones; Michael C O'Donovan; Michael J Owen; Julie Williams
Interaction between the ADAM12 and SH3MD1 genes may confer susceptibility to late-onset Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(4):448-52.
2007: Nick Craddock; Michael J Owen
Rethinking psychosis: the disadvantages of a dichotomous classification now outweigh the advantages.
World psychiatry : official journal of the World Psychiatric Association (WPA) 2007;6(2):84-91.
2007: B Nicholas; V Rudrasingham; S Nash; G Kirov; Michael J Owen; Dawn C Wimpory
Association of Per1 and Npas2 with autistic disorder: support for the clock genes/social timing hypothesis.
Molecular psychiatry 2007;12(6):581-92.
2007: Hywel J Williams; Michael J Owen; Michael C O'Donovan
Is COMT a susceptibility gene for schizophrenia?
Schizophrenia bulletin 2007;33(3):635-41.
2007: Andrew Grupe; Richard Abraham; Yonghong Li; Charles Rowland; Paul Hollingworth; Angharad Morgan; Luke Jehu; Ricardo Segurado; David Stone; Eric Schadt; Maha Karnoub; Petra Nowotny; Kristina Tacey; Joseph J Catanese; John J Sninsky; Carol Brayne; David C Rubinsztein; Michael Gill; Brian A Lawlor; Simon Lovestone; Peter Holmans; Michael O'Donovan; John C Morris; Leon J Thal; Alison Goate; Michael J Owen; Julie Williams
Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants.
Human molecular genetics 2007;16(8):865-73.
2007: N Craddock; M C O'Donovan; Michael J Owen
Symptom dimensions and the Kraepelinian dichotomy.
The British journal of psychiatry : the journal of mental science 2007;190():361; author reply 361-2.
2007: Stéphanie Le Hellard; Andrew J Lee; Sarah Underwood; Pippa A Thomson; stewart morris; Helen S Torrance; Susan M Anderson; Richard R Adams; Pau Navarro; Andrea Christoforou; Lorna M Houlihan; Sevilla D Detera-Wadleigh; Michael J Owen; Philip Asherson; Walter J Muir; D H R Blackwood; Naomi R Wray; David J Porteous; Kathryn L Evans
Haplotype analysis and a novel allele-sharing method refines a chromosome 4p locus linked to bipolar affective disorder.
Biological psychiatry 2007;61(6):797-805.
2007: Nick Craddock; Michael C O'Donovan; Michael J Owen
Phenotypic and genetic complexity of psychosis. Invited commentary on ... Schizophrenia: a common disease caused by multiple rare alleles.
The British journal of psychiatry : the journal of mental science 2007;190():200-3.
2007: David Gunnell; Shon Lewis; J Wilkinson; Lyudmila Georgieva; G Smith Davey; Ian N M Day; Jeff M P Holly; Michael C O'Donovan; Michael J Owen; George Kirov; Stanley Zammit
IGF1, growth pathway polymorphisms and schizophrenia: a pooling study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(1):117-20.
2007: Gillian Hamilton; Petra Proitsi; Julie Williams; Michael O'Donovan; Michael J Owen; John Powell; Simon Lovestone
Complement factor H Y402H polymorphism is not associated with late-onset Alzheimer's disease.
Neuromolecular medicine 2007;9(4):331-4.
2007: Valentina Moskvina; Anne Farmer; Victoria Swainson; Joanna O'Leary; Cerise Gunasinghe; Michael J Owen; Nick Craddock; Peter McGuffin; Ania Korszun
Interrelationship of childhood trauma, neuroticism, and depressive phenotype.
Depression and anxiety 2007;24(3):163-8.
2006: Therese van Amelsvoort; nicole schmitz; Eileen Daly; Quinton Deeley; Hugo Critchley; Jayne Henry; Dene Robertson; Michael J Owen; Kieran C Murphy; Declan G M Murphy
Processing facial emotions in adults with velo-cardio-facial syndrome: functional magnetic resonance imaging.
The British journal of psychiatry : the journal of mental science 2006;189():560-1.
2006: Denise Harold; Silvia Paracchini; Thomas Scerri; M Dennis; Natalie Cope; Gary Hill; Valentina Moskvina; J Walter; Alexandra Richardson; Michael J Owen; John Stein; Eric Green; Michael C O'Donovan; Julie Williams; Anthony P Monaco
Further evidence that the KIAA0319 gene confers susceptibility to developmental dyslexia.
Molecular psychiatry 2006;11(12):1085-91, 1061.
2006: Beate Glaser; Valentina Moskvina; George Kirov; Kieran C Murphy; Hywel Williams; Nigel Williams; Michael J Owen; Michael C O'Donovan
Analysis of ProDH, COMT and ZDHHC8 risk variants does not support individual or interactive effects on schizophrenia susceptibility.
Schizophrenia research 2006;87(1-3):21-7.
2006: Stanley Zammit; Glyn Lewis; Anita Thapar; Richard Owen; Gaynor Jones; Susan Jones; Rob Sanders; Charis Milham; Ameera Mahdi; Michael C O'Donovan; Michael J Owen
Phenotypic variation between parent-offspring trios and non-trios in genetic studies of schizophrenia.
Journal of psychiatric research 2006;40(7):622-6.
2006: Paul Hollingworth; Marian Hamshere; Valentina Moskvina; Kimberley Dowzell; Pamela J Moore; Catherine Foy; Nicola Archer; Aoibhinn Lynch; Simon Lovestone; Carol Brayne; David C Rubinsztein; Brian A Lawlor; Mike Gill; Michael J Owen; Julie Williams
Four components describe behavioral symptoms in 1,120 individuals with late-onset Alzheimer's disease.
Journal of the American Geriatrics Society 2006;54(9):1348-54.
2006: Elaine K Green; Nadine Norton; Tim Peirce; Detelina Grozeva; George Kirov; Michael J Owen; Michael C O'Donovan; Nick Craddock
Evidence that a DISC1 frame-shift deletion associated with psychosis in a single family may not be a pathogenic mutation.
Molecular psychiatry 2006;11(9):798-9.
2006: Yonghong Li; Andrew Grupe; Charles Rowland; Petra Nowotny; John S K Kauwe; Scott Smemo; Anthony L Hinrichs; Kristina Tacey; Timothy A Toombs; Shirley Kwok; Joseph J Catanese; Thomas J White; Taylor J Maxwell; Paul Hollingworth; Richard Abraham; David C Rubinsztein; Carol Brayne; Fabienne Wavrant-De Vrièze; John Hardy; Michael O'Donovan; Simon Lovestone; John C Morris; Leon J Thal; Michael J Owen; Julie Williams; Alison Goate
DAPK1 variants are associated with Alzheimer's disease and allele-specific expression.
Human molecular genetics 2006;15(17):2560-8.
2006: Lyudmila Georgieva; Valentina Moskvina; Tim Peirce; Nadine Norton; Nicholas J Bray; Lesley Jones; Peter Holmans; Stuart Macgregor; Stanley Zammit; Jennifer Wilkinson; Hywel Williams; Ivan Nikolov; Nigel Williams; Dobril Ivanov; Kenneth L Davis; Vahram Haroutunian; Joseph Buxbaum; Nick Craddock; George Kirov; Michael J Owen; Michael C O'Donovan
Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(33):12469-74.
2006: Anita Thapar; Kate Langley; Michael O'Donovan; Michael J Owen
Refining the attention deficit hyperactivity disorder phenotype for molecular genetic studies.
Molecular psychiatry 2006;11(8):714-20.
2006: Michael E Talkowski; Howard Seltman; Anne S Bassett; Linda M Brzustowicz; Xiangning Chen; Kodavali V Chowdari; David A Collier; Quirino Cordeiro; Aiden P Corvin; Smita N Deshpande; Michael Egan; Michael Gill; Kenneth S Kendler; George Kirov; Leonard L Heston; Pat Levitt; David A Lewis; Tao Li; Karoly Mirnics; Derek W Morris; Nadine Norton; Michael C O'Donovan; Michael J Owen; Christian Richard; Prachi Semwal; Janet L Sobell; David St Clair; Richard E Straub; B K Thelma; Homero Vallada; Daniel R Weinberger; Nigel M Williams; Joel Wood; Feng Zhang; Bernie Devlin; Vishwajit L Nimgaonkar
Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples.
Biological psychiatry 2006;60(2):152-62.
2006: Mark I Rees; Kirsten Harvey; Brian R Pearce; Seo-Kyung Chung; Ian C Duguid; Philip Thomas; Sarah Beatty; Gail E Graham; Linlea Armstrong; Rita Shiang; Kim J Abbott; Sameer M Zuberi; John B P Stephenson; Michael J Owen; Marina A J Tijssen; Arn van den Maagdenberg; Trevor G Smart; Stéphane Supplisson; Robert Justin Harvey
Mutations in the gene encoding GlyT2 (SLC6A5) define a presynaptic component of human startle disease.
Nature genetics 2006;38(7):801-6.
2006: Marian Hamshere; Nigel M Williams; Nadine Norton; Hywel Williams; Alastair G Cardno; Stanley Zammit; Lisa Anne Jones; Kieran C Murphy; Robert D Sanders; G McCarthy; MY Gray; G Jones; Peter Holmans; Michael C O'Donovan; Michael J Owen; Nick Craddock
Genome wide significant linkage in schizophrenia conditioning on occurrence of depressive episodes.
Journal of medical genetics 2006;43(7):563-7.
2006: Gillian Hamilton; Farzana Samedi; Jo Knight; Nicola Archer; Catherine Foy; Sarah Walter; Darko Turic; Luke Jehu; Pamela Moore; Paul Hollingworth; Michael C O'Donovan; Julie Williams; Michael J Owen; Simon Lovestone; John F Powell
Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease.
Neuroscience letters 2006;401(1-2):77-80.
2006: Richard Paylor; Beate Glaser; Annalisa Mupo; Paris Ataliotis; Corinne Spencer; Angela Sobotka; Chelsey Sparks; Chul-Hee Choi; John S Oghalai; Sarah Curran; Kieran C Murphy; Stephen Monks; Nigel Williams; Michael C O'Donovan; Michael J Owen; Peter J Scambler; Elizabeth Lindsay
Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7729-34.
2006: Nick Craddock; Michael J Owen; Michael C O'Donovan
The catechol-O-methyl transferase (COMT) gene as a candidate for psychiatric phenotypes: evidence and lessons.
Molecular psychiatry 2006;11(5):446-58.
2006: Nigel M Williams; Elaine K Green; Stuart Macgregor; Sarah Dwyer; Nadine Norton; Hywel Williams; Rachel Raybould; Detelina Grozeva; Marian Hamshere; Stanley Zammit; Lisa Jones; Alastair G Cardno; George Kirov; Ian Jones; Michael C O'Donovan; Michael J Owen; Nick Craddock
Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder.
Archives of general psychiatry 2006;63(4):366-73.
2006: Ian P Blair; A F Chetcuti; Renee F Badenhop; Anna Scimone; Melissa J Moses; Linda J Adams; N Craddock; E Green; G Kirov; Michael J Owen; John B J Kwok; Jennifer A Donald; Philip B Mitchell; Peter R Schofield
Positional cloning, association analysis and expression studies provide convergent evidence that the cadherin gene FAT contains a bipolar disorder susceptibility allele.
Molecular psychiatry 2006;11(4):372-83.
2006: Nadine Norton; Hywel J Williams; Michael J Owen
An update on the genetics of schizophrenia.
Current opinion in psychiatry 2006;19(2):158-64.
2006: Stanley Zammit; Michael J Owen
Stressful life events, 5-HTT genotype and risk of depression.
The British journal of psychiatry : the journal of mental science 2006;188():199-201.
2006: Denise Harold; Stuart Macgregor; Cathryn E Patterson; Paul Hollingworth; Pamela Moore; Michael J Owen; Julie Williams; Michael O'Donovan; Peter Passmore; Stephen McIlroy; Lesley Jones
A single nucleotide polymorphism in CHAT influences response to acetylcholinesterase inhibitors in Alzheimer's disease.
Pharmacogenetics and genomics 2006;16(2):75-7.
2006: Nadine Norton; Valentina Moskvina; Derek W Morris; Nicholas J Bray; Stanley Zammit; Nigel M Williams; Hywel J Williams; Anna Preece; Sarah Dwyer; Jennifer C Wilkinson; Gillian Spurlock; George Kirov; Paul R Buckland; John L Waddington; Michael Gill; Aiden Corvin; Michael J Owen; Michael C O'Donovan
Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2006;141B(1):96-101.
2006: Nigel M Williams; Michael C O'Donovan; Michael J Owen
Chromosome 22 deletion syndrome and schizophrenia.
International review of neurobiology 2006;73():1-27.
2006: Valentina Moskvina; Nick Craddock; Peter Holmans; Michael J Owen; Michael C O'Donovan
Effects of differential genotyping error rate on the type I error probability of case-control studies.
Human heredity 2006;61(1):55-64.
2006: George Kirov; Ivan Nikolov; Lyudmila Georgieva; Valentina Moskvina; Michael J Owen; Michael C O'Donovan
Pooled DNA genotyping on Affymetrix SNP genotyping arrays.
BMC genomics 2006;7():27.
2006: Tim Peirce; Nicholas J Bray; Nigel M Williams; Nadine Norton; Valentina Moskvina; Anna Preece; Vahram Haroutunian; Joseph Buxbaum; Michael J Owen; Michael C O'Donovan
Convergent evidence for 2',3'-cyclic nucleotide 3'-phosphodiesterase as a possible susceptibility gene for schizophrenia.
Archives of general psychiatry 2006;63(1):18-24.
2006: Elaine K Green; Rachel Raybould; Stuart Macgregor; Sally Hyde; Allan H Young; Michael C O'Donovan; Michael J Owen; George Kirov; Lisa Jones; Ian Jones; Nick Craddock
Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK.
The British journal of psychiatry : the journal of mental science 2006;188():21-5.
2006: Andrew Grupe; Yonghong Li; Charles Rowland; Petra Nowotny; Anthony L Hinrichs; Scott Smemo; John S K Kauwe; Taylor J Maxwell; Sara Cherny; Lisa Doil; Kristina Tacey; Ryan van Luchene; Amanda Myers; Fabienne Wavrant-De Vrièze; Mona Kaleem; Paul Hollingworth; Luke Jehu; Catherine Foy; Nicola Archer; Gillian Hamilton; Peter Holmans; Chris M Morris; Joseph Catanese; John Sninsky; Thomas J White; John Powell; John Hardy; Michael O'Donovan; Simon Lovestone; Lesley Jones; John C Morris; Leon J Thal; Michael J Owen; Julie Williams; Alison Goate
A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
American journal of human genetics 2006;78(1):78-88.
2006: Nick Craddock; Michael C O'Donovan; Michael J Owen
Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology.
Schizophrenia bulletin 2006;32(1):9-16.
2006: Scott Smemo; Petra Nowotny; Anthony L Hinrichs; John S K Kauwe; Sara Cherny; Katherine Erickson; Amanda Myers; Mona Kaleem; Lauren Marlowe; Alison M Gibson; Paul Hollingworth; Michael C O'Donovan; Christopher M Morris; Peter Holmans; Simon Lovestone; John C Morris; Leon J Thal; Yonghong Li; Andrew Grupe; John Hardy; Michael J Owen; Julie Williams; Alison Goate
Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease.
Annals of neurology 2006;59(1):21-6.
2005: Peter McGuffin; Jo Knight; Gerome Breen; Shyama Brewster; Peter R Boyd; Nick Craddock; Mike Gill; Ania Korszun; Wolfgang Maier; Lefkos T Middleton; Ole Mors; Michael J Owen; Julia Perry; Martin Preisig; Theodore Reich; John Rice; Marcella Rietschel; Lisa Jones; Pak Sham; Anne E Farmer
Whole genome linkage scan of recurrent depressive disorder from the depression network study.
Human molecular genetics 2005;14(22):3337-45.
2005: Kate Langley; Darko Turic; Tim Peirce; Sophie Mills; Marianne B M van den Bree; Michael J Owen; Michael C O'Donovan; Anita Thapar
No support for association between the dopamine transporter (DAT1) gene and ADHD.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;139B(1):7-10.
2005: Anita Thapar; Kate Langley; Tom Fowler; Frances Rice; Darko Turic; Naureen Whittinger; John Aggleton; Marianne B M van den Bree; Michael J Owen; Michael O'Donovan
Catechol O-methyltransferase gene variant and birth weight predict early-onset antisocial behavior in children with attention-deficit/hyperactivity disorder.
Archives of general psychiatry 2005;62(11):1275-8.
2005: Anita Thapar; Michael O'Donovan; Michael J Owen
The genetics of attention deficit hyperactivity disorder.
Human molecular genetics 2005;14 Spec No. 2():R275-82.
2005: Marian Hamshere; Philip Bennett; Nigel Williams; Ricardo Segurado; Alastair G Cardno; Nadine Norton; David Lambert; Hywel Williams; George Kirov; Aiden Corvin; Peter Holmans; Lisa Jones; Ian Jones; Michael Gill; Michael C O'Donovan; Michael J Owen; Nick Craddock
Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13.
Archives of general psychiatry 2005;62(10):1081-8.
2005: Nigel M Williams; Michael C O'Donovan; Michael J Owen
Is the dysbindin gene (DTNBP1) a susceptibility gene for schizophrenia?
Schizophrenia bulletin 2005;31(4):800-5.
2005: B Glaser; George Kirov; Nicholas J Bray; Elaine Green; Michael C O'Donovan; Nick Craddock; Michael J Owen
Identification of a potential bipolar risk haplotype in the gene encoding the winged-helix transcription factor RFX4.
Molecular psychiatry 2005;10(10):920-7.
2005: Lindsey Kent; Elaine Green; Ziarih Hawi; Aiveen Kirley; Frank Dudbridge; Naomi Lowe; Rachel Raybould; Kate Langley; Nicholas J Bray; Michael Fitzgerald; Michael J Owen; Michael C O'Donovan; Michael Gill; Anita Thapar; Nick Craddock
Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD.
Molecular psychiatry 2005;10(10):939-43.
2005: A S Ahuja; Anita Thapar; Michael J Owen
Genetics of mental retardation.
Indian journal of medical sciences 2005;59(9):407-17.
2005: Hywel J Williams; Beate Glaser; Nigel M Williams; Nadine Norton; Stanley Zammit; Stuart Macgregor; George Kirov; Michael J Owen; Michael C O'Donovan
No association between schizophrenia and polymorphisms in COMT in two large samples.
The American journal of psychiatry 2005;162(9):1736-8.
2005: Michael J Owen; Nick Craddock; Michael C O'Donovan
Schizophrenia: genes at last?
Trends in genetics : TIG 2005;21(9):518-25.
2005: Y Li; Charles Rowland; Kristina Tacey; Joseph J Catanese; John J Sninsky; John Hardy; J Powell; Simon Lovestone; John C Morris; Leon J Thal; Alison Goate; Michael J Owen; Julie Williams; Andrew Grupe
The BDNF Val66Met polymorphism is not associated with late onset Alzheimer's disease in three case-control samples.
Molecular psychiatry 2005;10(9):809-10.
2005: David Lambert; Fiona Middle; Marian Hamshere; Ricardo Segurado; Rachel Raybould; Aiden Corvin; Elaine Green; E O'Mahony; Ivan Nikolov; T Mulcahy; S Haque; S Bort; Philip Bennett; Nadine Norton; Michael J Owen; George Kirov; Corinne Lendon; Lesley Jones; Ian Jones; Peter Holmans; Michael Gill; Nick Craddock
Stage 2 of the Wellcome Trust UK-Irish bipolar affective disorder sibling-pair genome screen: evidence for linkage on chromosomes 6q16-q21, 4q12-q21, 9p21, 10p14-p12 and 18q22.
Molecular psychiatry 2005;10(9):831-41.
2005: George Kirov; John Tredget; Rhys John; Michael J Owen; John H Lazarus
A cross-sectional and a prospective study of thyroid disorders in lithium-treated patients.
Journal of affective disorders 2005;87(2-3):313-7.
2005: Nicholas J Bray; Anna Preece; Nigel M Williams; Valentina Moskvina; Paul R Buckland; Michael J Owen; Michael C O'Donovan
Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression.
Human molecular genetics 2005;14(14):1947-54.
2005: Petra Nowotny; Anthony L Hinrichs; Scott Smemo; John S K Kauwe; Taylor Maxwell; Peter Holmans; Marian Hamshere; Darko Turic; Luke Jehu; Paul Hollingworth; Pamela Moore; Leslie Bryden; Amanda Myers; Lisa M Doil; Kristina M Tacey; Alison M Gibson; Ian G McKeith; Robert H Perry; Christopher M Morris; Leon J Thal; John C Morris; Michael C O'Donovan; Simon Lovestone; Andrew Grupe; John Hardy; Michael J Owen; Julie Williams; Alison Goate
Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;136B(1):62-8.
2005: Beate Glaser; Johannes Schumacher; Hywel J Williams; Rami Abou Jamra; Nikolai Ianakiev; Radoi Milev; Stephanie Ohlraun; Thomas G. Schulze; Piotr M Czerski; Joanna Hauser; Erik G Jönsson; Göran C Sedvall; Norman Klopp; Thomas Illig; Tim Becker; Peter Propping; Nigel M Williams; Sven Cichon; George Kirov; Marcella Rietschel; Kieran C Murphy; Michael C O'Donovan; Markus M Nöthen; Michael J Owen
No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples.
Biological psychiatry 2005;58(1):78-80.
2005: Darko Turic; Kate Langley; Hywel Williams; Nadine Norton; Nigel M Williams; Valentina Moskvina; Marianne B M van den Bree; Michael J Owen; Anita Thapar; Michael C O'Donovan
A family based study implicates solute carrier family 1-member 3 (SLC1A3) gene in attention-deficit/hyperactivity disorder.
Biological psychiatry 2005;57(11):1461-6.
2005: Elaine K Green; Rachel Raybould; Stuart Macgregor; Katherine Gordon-Smith; Jessica Heron; Sally Hyde; Detelina Grozeva; Marian Hamshere; Nigel Williams; Michael J Owen; Michael C O'Donovan; Lisa Jones; Ian Jones; George Kirov; Nick Craddock
Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder.
Archives of general psychiatry 2005;62(6):642-8.
2005: George Kirov; Michael C O'Donovan; Michael J Owen
Finding schizophrenia genes.
The Journal of clinical investigation 2005;115(6):1440-8.
2005: Peter Holmans; Marian Hamshere; Paul Hollingworth; Frances Rice; Nigel Tunstall; Sue Jones; Pamela Moore; Fabienne Wavrant DeVrieze; Amanda Myers; Richard Crook; Danielle Compton; Helen Marshall; David Meyer; Shantia Shears; Jeremy Booth; Dzanan Ramic; Nigel Williams; Nadine Norton; Richard Abraham; Pat Kehoe; Hywel Williams; Varuni Rudrasingham; Michael O'Donovan; Lesley Jones; John Hardy; Alison Goate; Simon Lovestone; Michael J Owen; Julie Williams
Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;135B(1):24-32.
2005: Nick Craddock; Michael J Owen
The beginning of the end for the Kraepelinian dichotomy.
The British journal of psychiatry : the journal of mental science 2005;186():364-6.
2005: Rachel Raybould; Elaine K Green; Stuart Macgregor; Katherine Gordon-Smith; Jessica Heron; Sally Hyde; Sian Caesar; Ivan Nikolov; Nigel Williams; Lisa Jones; Michael C O'Donovan; Michael J Owen; Ian Jones; George Kirov; Nick Craddock
Bipolar disorder and polymorphisms in the dysbindin gene (DTNBP1).
Biological psychiatry 2005;57(7):696-701.
2005: Natalie Cope; Denise Harold; Gary Hill; Valentina Moskvina; Jim Stevenson; Peter Holmans; Michael J Owen; Michael C O'Donovan; Julie Williams
Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia.
American journal of human genetics 2005;76(4):581-91.
2005: Valentina Moskvina; Nadine Norton; Nigel Williams; Peter Holmans; Michael J Owen; Michael O'Donovan
Streamlined analysis of pooled genotype data in SNP-based association studies.
Genetic epidemiology 2005;28(3):273-82.
2005: Nick Craddock; Michael C O'Donovan; Michael J Owen
The genetics of schizophrenia and bipolar disorder: dissecting psychosis.
Journal of medical genetics 2005;42(3):193-204.
2005: Yonghong Li; Paul Hollingworth; Pamela Moore; Catherine Foy; Nicola Archer; John Powell; Petra Nowotny; Peter Holmans; Michael O'Donovan; Kristina Tacey; Lisa Doil; Ryan van Luchene; Veronica Garcia; Charles Rowland; Kit Lau; Joseph Cantanese; John J Sninsky; John Hardy; Leon J Thal; John C Morris; Alison Goate; Simon Lovestone; Michael J Owen; Julie Williams; Andrew Grupe
Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease.
Human mutation 2005;25(3):270-7.
2005: Natalie Cope; Gary Hill; Marianne B M van den Bree; Denise Harold; Valentina Moskvina; E K Green; Michael J Owen; Julie Williams; Michael C O'Donovan
No support for association between dyslexia susceptibility 1 candidate 1 and developmental dyslexia.
Molecular psychiatry 2005;10(3):237-8.
2005: Darko Turic; Hywel Williams; Kate Langley; Michael J Owen; Anita Thapar; Michael C O'Donovan
A family based study of catechol-O-methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD).
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;133B(1):64-7.
2005: Michael J Owen; Michael C O'Donovan; Paul J Harrison
Schizophrenia: a genetic disorder of the synapse?
BMJ (Clinical research ed.) 2005;330(7484):158-9.
2005: Beate Glaser; George Kirov; Elaine Green; Nick Craddock; Michael J Owen
Linkage disequilibrium mapping of bipolar affective disorder at 12q23-q24 provides evidence for association at CUX2 and FLJ32356.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;132B(1):38-45.
2005: Michael J Owen
Genomic approaches to schizophrenia.
Clinical therapeutics 2005;27 Suppl A():S2-7.
2005: Nadine Norton; Michael J Owen
HTR2A: association and expression studies in neuropsychiatric genetics.
Annals of medicine 2005;37(2):121-9.
2005: Nadine Norton; Hywel J Williams; Sarah Dwyer; Dobril Ivanov; Anna Preece; Amy Gerrish; Nigel M Williams; Pamela Yerassimou; Stanley Zammit; Michael C O'Donovan; Michael J Owen
No evidence for association between polymorphisms in GRM3 and schizophrenia.
BMC psychiatry 2005;5():23.
2005: Elaine Green; Gareth P Elvidge; Nick Jacobsen; Beate Glaser; Ian Jones; Michael C O'Donovan; George Kirov; Michael J Owen; Nick Craddock
Localization of bipolar susceptibility locus by molecular genetic analysis of the chromosome 12q23-q24 region in two pedigrees with bipolar disorder and Darier's disease.
The American journal of psychiatry 2005;162(1):35-42.
2005: Albena Dimitrova; vihra milanova; S Krastev; Ivan Nikolov; Draga Toncheva; Michael J Owen; George Kirov
Association study of myo-inositol monophosphatase 2 (IMPA2) polymorphisms with bipolar affective disorder and response to lithium treatment.
The pharmacogenomics journal 2005;5(1):35-41.
2004: Nicholas J Bray; Luke Jehu; Valentina Moskvina; Joseph Buxbaum; Stella Dracheva; Vahram Haroutunian; Julie Williams; Paul R Buckland; Michael J Owen; Michael C O'Donovan
Allelic expression of APOE in human brain: effects of epsilon status and promoter haplotypes.
Human molecular genetics 2004;13(22):2885-92.
2004: Yonghong Li; Petra Nowotny; Peter Holmans; Scott Smemo; John S K Kauwe; Anthony L Hinrichs; Kristina Tacey; Lisa Doil; Ryan van Luchene; Veronica Garcia; Charles Rowland; Steve Schrodi; Diane Leong; Goran Gogic; Joanne Chan; Anibal Cravchik; David Ross; Kit Lau; Shirley Kwok; Sheng-Yung Chang; Joe Catanese; John Sninsky; Thomas J White; John Hardy; John Powell; Simon Lovestone; John C Morris; Leon J Thal; Michael J Owen; Julie Williams; Alison Goate; Andrew Grupe
Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(44):15688-93.
2004: Therese van Amelsvoort; Eileen Daly; Jayne Henry; Dene Robertson; Virginia Ng; Michael J Owen; Kieran C Murphy; Declan G M Murphy
Brain anatomy in adults with velocardiofacial syndrome with and without schizophrenia: preliminary results of a structural magnetic resonance imaging study.
Archives of general psychiatry 2004;61(11):1085-96.
2004: Therese van Amelsvoort; Jayne Henry; Robin Morris; Michael J Owen; Don Linszen; Kieran Murphy; Declan Murphy
Cognitive deficits associated with schizophrenia in velo-cardio-facial syndrome.
Schizophrenia research 2004;70(2-3):223-32.
2004: Jane E Farbrother; George Kirov; Michael J Owen; Ricardo Pong-Wong; Chris S Haley; Jeremy A Guggenheim
Linkage analysis of the genetic loci for high myopia on 18p, 12q, and 17q in 51 U.K. families.
Investigative ophthalmology & visual science 2004;45(9):2879-85.
2004: Jane E Farbrother; George Kirov; Michael J Owen; Jeremy A Guggenheim
Family aggregation of high myopia: estimation of the sibling recurrence risk ratio.
Investigative ophthalmology & visual science 2004;45(9):2873-8.
2004: Yonghong Li; Kristina Tacey; Lisa Doil; Ryan van Luchene; Veronica Garcia; Charles Rowland; Steven J Schrodi; Diane Leong; Kit Lau; Joseph J Catanese; John J Sninsky; Petra Nowotny; Peter Holmans; John Hardy; John Powell; Simon Lovestone; Leon J Thal; Michael J Owen; Julie Williams; Alison Goate; Andrew Grupe
Association of ABCA1 with late-onset Alzheimer's disease is not observed in a case-control study.
Neuroscience letters 2004;366(3):268-71.
2004: Derek W Morris; D Ivanov; L Robinson; Nigel Williams; J Stevenson; Michael J Owen; Julie Williams; Michael C O'Donovan
Association analysis of two candidate phospholipase genes that map to the chromosome 15q15.1-15.3 region associated with reading disability.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;129B(1):97-103.
2004: Sven Cichon; Silvia Buervenich; George Kirov; Nirmala Akula; Albena Dimitrova; Elaine Green; Johannes Schumacher; Norman Klopp; Tim Becker; Stephanie Ohlraun; Thomas G. Schulze; Monja Tullius; Magdalena M Gross; Lisa Jones; Stefan Krastev; Ivan Nikolov; Marian Hamshere; Ian Jones; Piotr M Czerski; Anna Leszczynska-Rodziewicz; Pawel Kapelski; Ann Van Den Bogaert; Thomas Illig; Joanna Hauser; Wolfgang Maier; Wade Berrettini; William Byerley; William Coryell; Elliot S Gershon; John R Kelsoe; Melvin G McInnis; Dennis L Murphy; John I Nurnberger; Theodore Reich; William Scheftner; Michael C O'Donovan; Peter Propping; Michael J Owen; Marcella Rietschel; Markus M Nöthen; Francis McMajon; Nick Craddock
Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin.
Nature genetics 2004;36(8):783-4; author reply 784-5.
2004: B J Mowry; P A Holmans; Ann E Pulver; P V Gejman; B Riley; N M Williams; C Laurent; S G Schwab; D B Wildenauer; S Bauché; Michael J Owen; B Wormley; A R Sanders; Gerald Nestadt; Kung-Yee Liang; J Duan; R Ribble; Nadine Norton; S Soubigou; W Maier; K R Ewen-White; N DeMarchi; B Carpenter; D Walsh; H Williams; M Jay; M Albus; D A Nertney; G Papadimitriou; A O'Neill; M C O'Donovan; J-F Deleuze; F B Lerer; D Dikeos; K S Kendler; J Mallet; Jeremy Silverman; R R Crowe; D F Levinson
Multicenter linkage study of schizophrenia loci on chromosome 22q.
Molecular psychiatry 2004;9(8):784-95.
2004: Stanley Zammit; Gaynor Jones; Susan J Jones; Nadine Norton; Robert D Sanders; Charis Milham; Geraldine M McCarthy; Lisa Anne Jones; Alastair G Cardno; Marion Gray; Kieran C Murphy; Michael C O'Donovan; Michael J Owen
Polymorphisms in the MAOA, MAOB, and COMT genes and aggressive behavior in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;128B(1):19-20.
2004: Kirsten Harvey; Ian C Duguid; Melissa J Alldred; Sarah E Beatty; Hamish Ward; Nicholas H Keep; Sue E Lingenfelter; Brian R Pearce; Johan Lundgren; Michael J Owen; Trevor G Smart; Bernhard Lüscher; Mark I Rees; Robert Justin Harvey
The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(25):5816-26.
2004: Suzanne J Reid; Willeke van Roon-Mom; Phil C Wood; Mark I Rees; Michael J Owen; Richard L M Faull; Michael Dragunow; Russell G Snell
TBP, a polyglutamine tract containing protein, accumulates in Alzheimer's disease.
Brain research. Molecular brain research 2004;125(1-2):120-8.
2004: Nigel M Williams; Michael J Owen
Genetic abnormalities of chromosome 22 and the development of psychosis.
Current psychiatry reports 2004;6(3):176-82.
2004: Robert Plomin; D M Turic; L Hill; D E Turic; M Stephens; J Williams; Michael J Owen; M C O'Donovan
A functional polymorphism in the succinate-semialdehyde dehydrogenase (aldehyde dehydrogenase 5 family, member A1) gene is associated with cognitive ability.
Molecular psychiatry 2004;9(6):582-6.
2004: George Kirov; Dobril Ivanov; Nigel M Williams; Anna Preece; Ivan Nikolov; Radoi Milev; Svetlinka Koleva; Albena Dimitrova; Draga Toncheva; Michael C O'Donovan; Michael J Owen
Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from Bulgaria.
Biological psychiatry 2004;55(10):971-5.
2004: Darko Turic; Kate Langley; George Kirov; Michael J Owen; Anita Thapar; Michael C O'Donovan
Direct analysis of the genes encoding G proteins G alpha T2, G alpha o, G alpha Z in ADHD.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;127B(1):68-72.
2004: Michael J Owen; Nigel M Williams; Michael C O'Donovan
Dysbindin-1 and schizophrenia: from genetics to neuropathology.
The Journal of clinical investigation 2004;113(9):1255-7.
2004: Ania Korszun; Valentina Moskvina; Shyama Brewster; Nick Craddock; François Ferrero; Michael Gill; Ian Richard Jones; Lisa Anne Jones; Wolfgang Maier; Ole Mors; Michael J Owen; Martin Preisig; Theodore Reich; Marcella Rietschel; Anne Farmer; Peter McGuffin
Familiality of symptom dimensions in depression.
Archives of general psychiatry 2004;61(5):468-74.
2004: Abebaw Fekadu; Teshome Shibre; Atalay Alem; Derege Kebede; Samuel Kebreab; Alemayehu Negash; Michael J Owen
Bipolar disorder among an isolated island community in Ethiopia.
Journal of affective disorders 2004;80(1):1-10.
2004: Nigel M Williams; Anna Preece; Derek W Morris; Gillian Spurlock; Nicholas J Bray; M Stephens; Nadine Norton; Hywel Williams; M Clement; Sarah Dwyer; C Curran; J Wilkinson; Valentina Moskvina; John L Waddington; Michael Gill; Aiden Corvin; Stanley Zammit; George Kirov; Michael J Owen; Michael C O'Donovan
Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1).
Archives of general psychiatry 2004;61(4):336-44.
2004: Lynnette J Cook; Luk W Ho; Alison E Taylor; Carol Brayne; John Grimley Evans; John H Xuereb; Nigel J Cairns; Antonia Pritchard; Helen Lemmon; D M A Mann; David St Clair; Darko Turic; Paul Hollingworth; Pamela J Moore; Luke Jehu; Nicola Archer; Sarah Walter; Catherine Foy; Amanda Edmondson; John Powell; Simon Lovestone; Michael J Owen; Julie Williams; Corinne Lendon; David C Rubinsztein
Candidate gene association studies of the alpha 4 (CHRNA4) and beta 2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease.
Neuroscience letters 2004;358(2):142-6.
2004: Darko Turic; Kate Langley; Sophie Mills; M Stephens; Deborah Lawson; C Govan; Nigel Williams; Marianne B M van den Bree; Nick Craddock; Lindsey Kent; Michael J Owen; Michael O'Donovan; Anita Thapar
Follow-up of genetic linkage findings on chromosome 16p13: evidence of association of N-methyl-D aspartate glutamate receptor 2A gene polymorphism with ADHD.
Molecular psychiatry 2004;9(2):169-73.
2004: Nigel M Williams; Anna Preece; Gillian Spurlock; Nadine Norton; Hywel J Williams; Robin G McCreadie; Paul R Buckland; Val Sharkey; Kodavali V Chowdari; Stanley Zammit; Vishwajit L Nimgaonkar; George Kirov; Michael J Owen; Michael C O'Donovan
Support for RGS4 as a susceptibility gene for schizophrenia.
Biological psychiatry 2004;55(2):192-5.
2004: Anne Farmer; Gerome Breen; Shyama Brewster; Nick Craddock; Mike Gill; Ania Korszun; Wolfgang Maier; Lefkos T Middleton; Ole Mors; Michael J Owen; Julia Perry; Martin Preisig; Marcella Rietschel; Theodore Reich; Lisa Jones; Ian Jones; Peter McGuffin
The Depression Network (DeNT) Study: methodology and sociodemographic characteristics of the first 470 affected sibling pairs from a large multi-site linkage genetic study.
BMC psychiatry 2004;4():42.
2004: Sophie Mills; Kate Langley; Marianne B M van den Bree; Eddy Street; Darko Turic; Michael J Owen; Michael C O'Donovan; Anita Thapar
No evidence of association between Catechol-O-Methyltransferase (COMT) Val158Met genotype and performance on neuropsychological tasks in children with ADHD: a case-control study.
BMC psychiatry 2004;4():15.
2004: Nadine Norton; Nigel M Williams; Michael C O'Donovan; Michael J Owen
DNA pooling as a tool for large-scale association studies in complex traits.
Annals of medicine 2004;36(2):146-52.
2004: Victoria Busby; Steven Goossens; Petra Nowotny; Gillian Hamilton; Scott Smemo; Denise Harold; Dragana Turic; Luke Jehu; Amanda Myers; Meredith Womick; Daniel Woo; Danielle Compton; Lisa M Doil; Kristina M Tacey; Kit F Lau; Safa Al-Saraj; Richard Killick; Stuart Pickering-Brown; Pamela Moore; Paul Hollingworth; Nicola Archer; Catherine Foy; Sarah Walter; Corrine Lendon; Takeshi Iwatsubo; John C Morris; Joanne Norton; D M A Mann; Barbara Janssens; John Hardy; Michael O'Donovan; Lesley Jones; Julie Williams; Peter Holmans; Michael J Owen; Andrew Grupe; John Powell; Jolanda van Hengel; Alison Goate; Frans Van Roy; Simon Lovestone
Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease.
Neuromolecular medicine 2004;5(2):133-46.
2004: Kate Langley; Lucy Marshall; Marianne B M van den Bree; Hollie Thomas; Michael J Owen; Michael O'Donovan; Anita Thapar
Association of the dopamine D4 receptor gene 7-repeat allele with neuropsychological test performance of children with ADHD.
The American journal of psychiatry 2004;161(1):133-8.
2004: Nicholas J Bray; Paul R Buckland; Håkan Hall; Michael J Owen; Michael C O'Donovan
The serotonin-2A receptor gene locus does not contain common polymorphism affecting mRNA levels in adult brain.
Molecular psychiatry 2004;9(1):109-14.
2004: Amanda Myers; Helen Marshall; Peter Holmans; Danielle Compton; Richard Crook; adrian mander; Petra Nowotny; Scott Smemo; Melanie Dunstan; Luke Jehu; Jen C Wang; Marian Hamshere; John C Morris; Joanne Norton; Sumi Chakraventy; Nigel Tunstall; Simon Lovestone; Ronald C. Petersen; Michael O'Donovan; Lesley Jones; Julie Williams; Michael J Owen; John Hardy; Alison Goate
Variation in the urokinase-plasminogen activator gene does not explain the chromosome 10 linkage signal for late onset AD.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;124B(1):29-37.
2004: Michael J Owen; Nigel M Williams; Michael C O'Donovan
The molecular genetics of schizophrenia: new findings promise new insights.
Molecular psychiatry 2004;9(1):14-27.
2003: Jessica Heron; I Jones; J Williams; Michael J Owen; N Craddock; L A Jones
Self-reported schizotypy and bipolar disorder: demonstration of a lack of specificity of the Kings Schizotypy Questionnaire.
Schizophrenia research 2003;65(2-3):153-8.
2003: Nigel M Williams; Nadine Norton; Hywel Williams; Birgit Ekholm; Marian Hamshere; Y Lindblom; Kodavali V Chowdari; Alastair G Cardno; Stanley Zammit; Lisa Anne Jones; Kieran C Murphy; Robert D Sanders; G McCarthy; MY Gray; G Jones; Peter Holmans; Vishwajit L Nimgaonkar; R Adolfson; Urban Osby; L Terenius; Göran C Sedvall; Michael C O'Donovan; Michael J Owen
A systematic genomewide linkage study in 353 sib pairs with schizophrenia.
American journal of human genetics 2003;73(6):1355-67.
2003: R M Marchbanks; Margaret Ryan; I N M Day; Michael J Owen; Peter McGuffin; Stephen A Whatley
A mitochondrial DNA sequence variant associated with schizophrenia and oxidative stress.
Schizophrenia research 2003;65(1):33-8.
2003: Dobril Ivanov; George Kirov; Nadine Norton; Hywel J Williams; Nigel M Williams; Ivan Nikolov; R Tzwetkova; S M Stambolova; Kieran C Murphy; Draga Toncheva; Anita Thapar; Michael C O'Donovan; Michael J Owen
Chromosome 22q11 deletions, velo-cardio-facial syndrome and early-onset psychosis. Molecular genetic study.
The British journal of psychiatry : the journal of mental science 2003;183():409-13.
2003: Stanley Zammit; Peter Allebeck; Christina Dalman; Ingvar Lundberg; Tomas Hemmingson; Michael J Owen; Glyn Lewis
Paternal age and risk for schizophrenia.
The British journal of psychiatry : the journal of mental science 2003;183():405-8.
2003: Michael C O'Donovan; Nigel M Williams; Michael J Owen
Recent advances in the genetics of schizophrenia.
Human molecular genetics 2003;12 Spec No 2():R125-33.
2003: George Kirov; Lyudmila Georgieva; Nigel Williams; Ivan Nikolov; Nadine Norton; Draga Toncheva; Michael O'Donovan; Michael J Owen
Variation in the protocadherin gamma A gene cluster.
Genomics 2003;82(4):433-40.
2003: Antony Payton; Darko Turic; Kate Langley; Sophie Mills; Deborah C Lawson; Marianne B M van den Bree; Michael J Owen; Michael C O'Donovan; W E R Ollier; Jane Worthington; Anita Thapar
No evidence of association between HLA-DRB1 and attention deficit hyperactivity disorder.
Psychiatric genetics 2003;13(3):183-5.
2003: Denise Harold; Tim Peirce; Valentina Moskvina; Amanda Myers; Susan Jones; Paul Hollingworth; Pamela Moore; Simon Lovestone; John Powell; Catherine Foy; Nicola Archer; Sarah Walter; Amanda Edmonson; Stephen McIlroy; David Craig; Peter Passmore; Alison Goate; John Hardy; Michael O'Donovan; Julie Williams; Malcolm Liddell; Michael J Owen; Lesley Jones
Sequence variation in the CHAT locus shows no association with late-onset Alzheimer's disease.
Human genetics 2003;113(3):258-67.
2003: Mark I Rees; Kirsten Harvey; Hamish Ward; Julia H White; Luc Evans; Ian C Duguid; Cynthia C-H Hsu; Sharon L Coleman; Jan Miller; Kristin Baer; Henry J Waldvogel; Francis Gibbon; Trevor G Smart; Michael J Owen; Robert Justin Harvey; Russell G Snell
Isoform heterogeneity of the human gephyrin gene (GPHN), binding domains to the glycine receptor, and mutation analysis in hyperekplexia.
The Journal of biological chemistry 2003;278(27):24688-96.
2003: Hywel J Williams; Nigel Williams; Gillian Spurlock; Nadine Norton; Dobril Ivanov; Robin G McCreadie; Anna Preece; Val Sharkey; Sue Jones; Stanley Zammit; Ivan Nikolov; I Kehaiov; Anita Thapar; Kieran C Murphy; George Kirov; Michael J Owen; Michael C O'Donovan
Association between PRODH and schizophrenia is not confirmed.
Molecular psychiatry 2003;8(7):644-5.
2003: Hywel J Williams; Nigel Williams; Gillian Spurlock; Nadine Norton; Stanley Zammit; George Kirov; Michael J Owen; Michael C O'Donovan
Detailed analysis of PRODH and PsPRODH reveals no association with schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;120B(1):42-6.
2003: Nadine Norton; Hywel J Williams; Nigel M Williams; Gillian Spurlock; Stanley Zammit; Gaynor Jones; Sue Jones; Richard Owen; Michael C O'Donovan; Michael J Owen
Mutation screening of the Homer gene family and association analysis in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;120B(1):18-21.
2003: Cathryn M Lewis; Douglas F Levinson; Lesley H Wise; Lynn E DeLisi; Richard E Straub; Iiris Hovatta; Nigel M Williams; Sibylle G Schwab; Ann E Pulver; Stephen Faraone; Linda M Brzustowicz; Charles A Kaufmann; David L Garver; Hugh M D Gurling; Eva Lindholm; Hilary Coon; Hans W Moises; William Byerley; Sarah H Shaw; Andrea Mesen; Robin Sherrington; Francis Anthony O'Neill; Dermot Walsh; Kenneth S Kendler; Jesper Ekelund; Tiina Paunio; Jouko Lönnqvist; Leena Peltonen; Michael C O'Donovan; Michael J Owen; Dieter B Wildenauer; Wolfgang Maier; Gerald Nestadt; Jean-Louis Blouin; Stylianos Antonarakis; Bryan J Mowry; Jeremy Silverman; Raymond R Crowe; C Robert Cloninger; Ming T Tsuang; Dolores Malaspina; Jill M Harkavy-Friedman; Dragan M Svrakic; Anne S Bassett; Jennifer Holcomb; Gursharan Kalsi; Andrew McQuillin; Jon Brynjolfson; Thordur Sigmundsson; Hannes Petursson; Elena Jazin; Tomas Zoëga; Tomas Helgason
Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia.
American journal of human genetics 2003;73(1):34-48.
2003: Nicholas J Bray; Paul R Buckland; Nigel M Williams; Hywel J Williams; Nadine Norton; Michael J Owen; Michael C O'Donovan
A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain.
American journal of human genetics 2003;73(1):152-61.
2003: Nicholas J Bray; Paul R Buckland; Michael J Owen; Michael C O'Donovan
Cis-acting variation in the expression of a high proportion of genes in human brain.
Human genetics 2003;113(2):149-53.
2003: Kate Langley; Antony Payton; Marian Hamshere; Helen M Pay; Deborah C Lawson; Darko Turic; W E R Ollier; Jane Worthington; Michael J Owen; Michael C O'Donovan; Anita Thapar
No evidence of association of two 5HT transporter gene polymorphisms and attention deficit hyperactivity disorder.
Psychiatric genetics 2003;13(2):107-10.
2003: Lyudmila Georgieva; Ivan Nikolov; Nadezhda Poriazova; Gaynor Jones; Draga Toncheva; George Kirov; Michael J Owen
Genetic variation in the seven-pass transmembrane cadherin CELSR1: lack of association with schizophrenia.
Psychiatric genetics 2003;13(2):103-6.
2003: Elaine K Green; Gareth P Elvidge; Michael J Owen; Nick Craddock
Mutational analysis of two positional candidate susceptibility genes for bipolar disorder on chromosome 12q23-q24: phenylalanine hydroxylase and human LIM-homeobox LHX5.
Psychiatric genetics 2003;13(2):97-101.
2003: Suzanne J Reid; Mark I Rees; Willeke van Roon-Mom; A Lesley Jones; Marcy E MacDonald; Greg Sutherland; Matthew J During; Richard L M Faull; Michael J Owen; Michael Dragunow; Russell G Snell
Molecular investigation of TBP allele length: a SCA17 cellular model and population study.
Neurobiology of disease 2003;13(1):37-45.
2003: Nigel M Williams; Anna Preece; Gillian Spurlock; Nadine Norton; Hywel J Williams; Stanley Zammit; Michael C O'Donovan; Michael J Owen
Support for genetic variation in neuregulin 1 and susceptibility to schizophrenia.
Molecular psychiatry 2003;8(5):485-7.
2003: Erik G Jönsson; Nadine Norton; Kaj Forslund; Marja Mattila-Evenden; Gunnar Rylander; Marie Asberg; Michael J Owen; Göran C Sedvall
Association between a promoter variant in the monoamine oxidase A gene and schizophrenia.
Schizophrenia research 2003;61(1):31-7.
2003: George Kirov; Lyudmila Georgieva; Ivan Nikolov; Stanley Zammit; Gaynor Jones; Nadezhda Poriazova; Todor Tolev; Richard Owen; Sue Jones; Michael J Owen
Association analysis of the HOPA12bp polymorphism in schizophrenia and manic depressive illness.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;118B(1):16-9.
2003: Darko Turic; L Robinson; M Duke; Derek W Morris; V Webb; Marian Hamshere; Charis Milham; Elizabeth Hopkin; K Pound; S Fernando; A Grierson; M Easton; Nigel Williams; Marianne B M van den Bree; R Chowdhury; J Gruen; J Stevenson; Michael Krawczak; Michael J Owen; Michael C O'Donovan; Julie Williams
Linkage disequilibrium mapping provides further evidence of a gene for reading disability on chromosome 6p21.3-22.
Molecular psychiatry 2003;8(2):176-85.
2003: Paul J Harrison; Michael J Owen
Genes for schizophrenia? Recent findings and their pathophysiological implications.
Lancet 2003;361(9355):417-9.
2003: Frances Rice; Richard Abraham; Varuni Rudrasingham; Michael J Owen; Julie Williams
Memory for new information as a cognitive marker of liability to Alzheimer's disease in a high risk group: a research note.
International journal of geriatric psychiatry 2003;18(2):155-60.
2003: Anders D Børglum; G Kirov; N Craddock; Ole Mors; Walter Muir; V Murray; I McKee; David A Collier; Henrik Ewald; Michael J Owen; D H R Blackwood; Torben A Kruse
Possible parent-of-origin effect of Dopa decarboxylase in susceptibility to bipolar affective disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;117B(1):18-22.
2003: Marianne B M van den Bree; Michael J Owen
The future of psychiatric genetics.
Annals of medicine 2003;35(2):122-34.
2003: Deborah C Lawson; Darko Turic; Kate Langley; Helen M Pay; Catherine F Govan; Nadine Norton; Marian Hamshere; Michael J Owen; Michael C O'Donovan; Anita Thapar
Association analysis of monoamine oxidase A and attention deficit hyperactivity disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;116B(1):84-9.
2002: Pak Sham; Joel S Bader; Ian Craig; Michael O'Donovan; Michael J Owen
DNA Pooling: a tool for large-scale association studies.
Nature reviews. Genetics 2002;3(11):862-71.
2002: Albena Dimitrova; Lyudmila Georgieva; Ivan Nikolov; Nadezhda Poriazova; Stefan Krastev; Draga Toncheva; Michael J Owen; George Kirov
Major psychiatric disorders and the serotonin transporter gene (SLC6A4): family-based association studies.
Psychiatric genetics 2002;12(3):137-41.
2002: Allan J Richards; J Morgan; P W P Bearcroft; E Pickering; Michael J Owen; P Holmans; N Williams; C Tysoe; F Michael Pope; Martin P Snead; H Hughes
Vitreoretinopathy with phalangeal epiphyseal dysplasia, a type II collagenopathy resulting from a novel mutation in the C-propeptide region of the molecule.
Journal of medical genetics 2002;39(9):661-5.
2002: Harvey Wickham; Cathy Walsh; Philip Asherson; Mike Gill; Michael J Owen; Peter McGuffin; Robin Murray; Pak Sham
Familiality of clinical characteristics in schizophrenia.
Journal of psychiatric research 2002;36(5):325-9.
2002: Nicholas J Bray; George Kirov; R J Owen; NJ Jacobsen; Lyudmila Georgieva; Hywel J Williams; Nadine Norton; Gillian Spurlock; Sue Jones; Stanley Zammit; Michael C O'Donovan; Michael J Owen
Screening the human protocadherin 8 (PCDH8) gene in schizophrenia.
Genes, brain, and behavior 2002;1(3):187-91.
2002: Nadine Norton; George Kirov; Stanley Zammit; Gaynor Jones; Susan Jones; Richard Owen; Michael Krawczak; Nigel M Williams; Michael C O'Donovan; Michael J Owen
Schizophrenia and functional polymorphisms in the MAOA and COMT genes: no evidence for association or epistasis.
American journal of medical genetics 2002;114(5):491-6.
2002: Nadine Norton; Nigel M Williams; Hywel J Williams; Gillian Spurlock; George Kirov; Derek W Morris; Bastiaan Hoogendoorn; Michael J Owen; Michael C O'Donovan
Universal, robust, highly quantitative SNP allele frequency measurement in DNA pools.
Human genetics 2002;110(5):471-8.
2002: Lyudmila Georgieva; Albena Dimitrova; Ivan Nikolov; S Koleva; R Tsvetkova; Michael J Owen; Draga Toncheva; George Kirov
Dopamine transporter gene (DAT1) VNTR polymorphism in major psychiatric disorders: family-based association study in the Bulgarian population.
Acta psychiatrica Scandinavica 2002;105(5):396-9.
2002: Douglas F Levinson; Peter A Holmans; Claudine Laurent; Brien Riley; Ann E Pulver; Pablo V Gejman; Sibylle G Schwab; Nigel M Williams; Michael J Owen; Dieter B Wildenauer; Alan R Sanders; Gerald Nestadt; Bryan J Mowry; Brandon Wormley; Stephanie Bauché; Stephane Soubigou; Robert Ribble; Deborah A Nertney; Kung-Yee Liang; Laura Martinolich; Wolfgang Maier; Nadine Norton; Hywel Williams; Margot Albus; Eric B Carpenter; Nicola DeMarchi; Kelly R Ewen-White; Dermot Walsh; Maurice Jay; Jean-François Deleuze; Francis Anthony O'Neill; George Papadimitriou; Ann Weilbaecher; Bernard Lerer; Michael C O'Donovan; Dimitris Dikeos; Jeremy Silverman; Kenneth S Kendler; Jacques Mallet; Raymond R Crowe; Marilyn Walters
No major schizophrenia locus detected on chromosome 1q in a large multicenter sample.
Science (New York, N.Y.) 2002;296(5568):739-41.
2002: Mark I Rees; Trevor M Lewis; John B J Kwok; Geert R Mortier; Paul Govaert; Russell G Snell; Peter R Schofield; Michael J Owen
Hyperekplexia associated with compound heterozygote mutations in the beta-subunit of the human inhibitory glycine receptor (GLRB).
Human molecular genetics 2002;11(7):853-60.
2002: Amanda Myers; Fabienne Wavrant De-Vrieze; Peter Holmans; Marian Hamshere; Richard Crook; Danielle Compton; Helen Marshall; David Meyer; Shantia Shears; Jeremy Booth; Dzanan Ramic; Heather Knowles; John C Morris; Nigel Williams; Nadine Norton; Richard Abraham; Pat Kehoe; Hywel Williams; Varuni Rudrasingham; Frances Rice; Peter Giles; Nigel Tunstall; Lesley Jones; Simon Lovestone; Julie Williams; Michael J Owen; John Hardy; Alison Goate
Full genome screen for Alzheimer disease: stage II analysis.
American journal of medical genetics 2002;114(2):235-44.
2002: Jane Holmes; Antony Payton; Jennifer Barrett; Richard Harrington; Peter McGuffin; Michael J Owen; W E R Ollier; Jane Worthington; Michael Gill; Aiveen Kirley; Ziarih Hawi; Michael Fitzgerald; Philip Asherson; Sarah Rosario Curran; Jonathan Mill; Alison Gould; Eric Taylor; Lindsey Kent; Nick Craddock; Anita Thapar
Association of DRD4 in children with ADHD and comorbid conduct problems.
American journal of medical genetics 2002;114(2):150-3.
2002: Håkan Garpenstrand; Nadine Norton; Mattias Damberg; Gunnar Rylander; Kaj Forslund; Marja Mattila-Evenden; J Petter Gustavsson; Jonas Ekblom; Lars Oreland; Hans Bergman; Michael J Owen; Erik G Jönsson
A regulatory monoamine oxidase a promoter polymorphism and personality traits.
Neuropsychobiology 2002;46(4):190-3.
2002: Nigel M Williams; Gillian Spurlock; Nadine Norton; Hywel J Williams; Marian Hamshere; Michael Krawczak; George Kirov; Ivan Nikolov; Lyudmila Georgieva; Sue Jones; Alastair G Cardno; Michael C O'Donovan; Michael J Owen
Mutation screening and LD mapping in the VCFS deleted region of chromosome 22q11 in schizophrenia using a novel DNA pooling approach.
Molecular psychiatry 2002;7(10):1092-100.
2002: A West; Kate Langley; Marian Hamshere; Lindsey Kent; Nick Craddock; Michael J Owen; Michael O'Donovan; Anita Thapar
Evidence to suggest biased phenotypes in children with Attention Deficit Hyperactivity Disorder from completely ascertained trios.
Molecular psychiatry 2002;7(9):962-6.
2002: Ziarih Hawi; M Dring; Aiveen Kirley; D Foley; Lindsey Kent; Nick Craddock; Philip Asherson; Sarah Rosario Curran; Alison Gould; Sandra Richards; Deborah Lawson; Helen M Pay; Darko Turic; Kate Langley; Michael J Owen; Michael O'Donovan; Anita Thapar; Michael Fitzgerald; Michael Gill
Serotonergic system and attention deficit hyperactivity disorder (ADHD): a potential susceptibility locus at the 5-HT(1B) receptor gene in 273 nuclear families from a multi-centre sample.
Molecular psychiatry 2002;7(7):718-25.
2002: Pamela Sklar; Stacey B Gabriel; Melvin G McInnis; P Bennett; Y -M Lim; G Tsan; Stephen F Schaffner; George Kirov; I Jones; Michael J Owen; N Craddock; J. Raymond DePaulo; Eric S Lander
Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor.
Molecular psychiatry 2002;7(6):579-93.
2002: Nigel M Williams; Timothy Bowen; Gillian Spurlock; Nadine Norton; Hywel J Williams; Bastiaan Hoogendoorn; Michael J Owen; Michael C O'Donovan
Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor.
Molecular psychiatry 2002;7(5):508-14.
2002: R J Anney; Mark I Rees; E Bryan; Gillian Spurlock; Nigel Williams; Nadine Norton; Hywel Williams; Alastair G Cardno; Stanley Zammit; Sue Jones; G Jones; Bastiaan Hoogendoorn; Kaye Smith; Marian Hamshere; S Coleman; Carol Guy; Michael C O'Donovan; Michael J Owen; Paul R Buckland
Characterisation, mutation detection, and association analysis of alternative promoters and 5' UTRs of the human dopamine D3 receptor gene in schizophrenia.
Molecular psychiatry 2002;7(5):493-502.
2002: Ian Jones; N Jacobsen; Elaine K Green; Gareth P Elvidge; Michael J Owen; Nick Craddock
Evidence for familial cosegregation of major affective disorder and genetic markers flanking the gene for Darier's disease.
Molecular psychiatry 2002;7(4):424-7.
2002: Nigel M Williams; Michael C O'Donovan; Michael J Owen
Genome scans and microarrays: converging on genes for schizophrenia?
Genome biology 2002;3(4):REVIEWS1011.
2002: Philip Bennett; Ricardo Segurado; Ian Jones; S Bort; Fiona McCandless; David Lambert; Jessica Heron; C Comerford; Fiona Middle; Aiden Corvin; G Pelios; George Kirov; B Larsen; T Mulcahy; Nigel Williams; R O'Connell; E O'Mahony; A Payne; Michael J Owen; Peter Holmans; Nick Craddock; Michael Gill
The Wellcome trust UK-Irish bipolar affective disorder sibling-pair genome screen: first stage report.
Molecular psychiatry 2002;7(2):189-200.
2002: J C Henry; Therese van Amelsvoort; Robin G Morris; Michael J Owen; Declan G M Murphy; Kieran C Murphy
An investigation of the neuropsychological profile in adults with velo-cardio-facial syndrome (VCFS).
Neuropsychologia 2002;40(5):471-8.
2001: Antony Payton; Jane Holmes; JH Barrett; P Sham; Richard Harrington; Peter McGuffin; Michael J Owen; W E R Ollier; Jane Worthington; Anita Thapar
Susceptibility genes for a trait measure of attention deficit hyperactivity disorder: a pilot study in a non-clinical sample of twins.
Psychiatry research 2001;105(3):273-8.
2001: Richard Abraham; Amanda Myers; Fabienne Wavrant DeVrieze; Marian Hamshere; Hollie V Thomas; Helen Marshall; Danielle Compton; Gillian Spurlock; Darko Turic; Bastiaan Hoogendoorn; Jennifer M Kwon; Ronald C. Petersen; Eric G Tangalos; J Norton; John C Morris; Ross Bullock; D Liolitsa; Simon Lovestone; John Hardy; Alison Goate; Michael O'Donovan; Julie Williams; Michael J Owen; Lesley Jones
Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease.
Human genetics 2001;109(6):646-52.
2001: I Jurewicz; R J Owen; M C O'Donovan; Michael J Owen
Searching for susceptibility genes in schizophrenia.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2001;11(6):395-8.
2001: Robert Plomin; Linzy Hill; Ian W Craig; Peter McGuffin; Shaun Purcell; Pak Sham; David Lubinski; Lee A Thompson; PJ Fisher; Darko Turic; Michael J Owen
A genome-wide scan of 1842 DNA markers for allelic associations with general cognitive ability: a five-stage design using DNA pooling and extreme selected groups.
Behavior genetics 2001;31(6):497-509.
2001: Kieran C Murphy; Michael J Owen
Velo-cardio-facial syndrome: a model for understanding the genetics and pathogenesis of schizophrenia.
The British journal of psychiatry : the journal of mental science 2001;179():397-402.
2001: George Kirov; C A Lowry; M Stephens; S Oldfield; Michael C O'Donovan; S L Lightman; Michael J Owen
Screening ABCG1, the human homologue of the Drosophila white gene, for polymorphisms and association with bipolar affective disorder.
Molecular psychiatry 2001;6(6):671-7.
2001: Gaynor Jones; Stanley Zammit; Nadine Norton; Marian Hamshere; S J Jones; Charis Milham; Robert D Sanders; Geraldine M McCarthy; Lisa Anne Jones; Alastair G Cardno; Marion Gray; Kieran C Murphy; Michael J Owen
Aggressive behaviour in patients with schizophrenia is associated with catechol-O-methyltransferase genotype.
The British journal of psychiatry : the journal of mental science 2001;179():351-5.
2001: Mark I Rees; Trevor M Lewis; B Vafa; Colin D Ferrie; Peter Corry; F Muntoni; Heinz Jungbluth; John B P Stephenson; M Kerr; Russell G Snell; Peter R Schofield; Michael J Owen
Compound heterozygosity and nonsense mutations in the alpha(1)-subunit of the inhibitory glycine receptor in hyperekplexia.
Human genetics 2001;109(3):267-70.
2001: Antony Payton; Jane Holmes; JH Barrett; Tracey Hever; Helen Fitzpatrick; Anne Trumper; Richard Harrington; Peter McGuffin; M O'Donovan; Michael J Owen; W E R Ollier; Jane Worthington; Anita Thapar
Examining for association between candidate gene polymorphisms in the dopamine pathway and attention-deficit hyperactivity disorder: a family-based study.
American journal of medical genetics 2001;105(5):464-70.
2001: Alastair G Cardno; Peter Holmans; Mark I Rees; Lisa Anne Jones; Geraldine M McCarthy; Marian Hamshere; Nigel M Williams; Nadine Norton; Hywel J Williams; Iain Fenton; Kieran C Murphy; Robert D Sanders; MY Gray; Michael C O'Donovan; Peter McGuffin; Michael J Owen
A genomewide linkage study of age at onset in schizophrenia.
American journal of medical genetics 2001;105(5):439-45.
2001: Pamela Sklar; Sibylle G Schwab; Nigel M Williams; Mark J Daly; Stephen F Schaffner; W Maier; Margot Albus; Mátyás Trixler; P Eichhammer; Bernard Lerer; Joachim Hallmayer; Nadine Norton; H Williams; Stanley Zammit; Alastair G Cardno; S Jones; G McCarthy; vihra milanova; George Kirov; M C O'Donovan; Eric S Lander; Michael J Owen; Dieter B Wildenauer
Association analysis of NOTCH4 loci in schizophrenia using family and population-based controls.
Nature genetics 2001;28(2):126-8.
2001: Gareth P Elvidge; Ian Jones; Fiona McCandless; Philip Asherson; Michael J Owen; Nick Craddock
Allelic variation of a BalI polymorphism in the DRD3 gene does not influence susceptibility to bipolar disorder: results of analysis and meta-analysis.
American journal of medical genetics 2001;105(4):307-11.
2001: Therese van Amelsvoort; Eileen Daly; Dene Robertson; John Suckling; Virginia Ng; Hugo Critchley; Michael J Owen; Jayne Henry; Kieran C Murphy; Declan G M Murphy
Structural brain abnormalities associated with deletion at chromosome 22q11: quantitative neuroimaging study of adults with velo-cardio-facial syndrome.
The British journal of psychiatry : the journal of mental science 2001;178():412-9.
2001: Timothy Bowen; N Williams; Nadine Norton; Gillian Spurlock; Oliver H Wittekindt; Deborah J Morris-Rosendahl; Hywel Williams; L Brzustowicz; Bastiaan Hoogendoorn; Stanley Zammit; G Jones; Robert D Sanders; Lisa Anne Jones; G McCarthy; S Jones; A Bassett; Alastair G Cardno; Michael J Owen; Michael C O'Donovan
Mutation screening of the KCNN3 gene reveals a rare frameshift mutation.
Molecular psychiatry 2001;6(3):259-60.
2001: NJ Jacobsen; Gareth P Elvidge; EK Franks; Michael C O'Donovan; Nick Craddock; Michael J Owen
CUX2, a potential regulator of NCAM expression: genomic characterization and analysis as a positional candidate susceptibility gene for bipolar disorder.
American journal of medical genetics 2001;105(3):295-300.
2001: Nicholas J Bray; Michael J Owen
Searching for schizophrenia genes.
Trends in molecular medicine 2001;7(4):169-74.
2001: Lisa Anne Jones; Alastair G Cardno; Robert D Sanders; Michael J Owen; J Williams
Sustained and selective attention as measures of genetic liability to schizophrenia.
Schizophrenia research 2001;48(2-3):263-72.
2001: Harvey Wickham; C Walsh; Philip Asherson; C Taylor; T Sigmundson; Mike Gill; Michael J Owen; Peter McGuffin; Robin Murray; Pak Sham
Familiality of symptom dimensions in schizophrenia.
Schizophrenia research 2001;47(2-3):223-32.
2001: Darko Turic; PJ Fisher; Robert Plomin; Michael J Owen
No association between apolipoprotein E polymorphisms and general cognitive ability in children.
Neuroscience letters 2001;299(1-2):97-100.
2001: NJ Jacobsen; EK Franks; Gareth P Elvidge; Ian Jones; Fiona McCandless; Michael C O'Donovan; Michael J Owen; Nick Craddock
Exclusion of the Darier's disease gene, ATP2A2, as a common susceptibility gene for bipolar disorder.
Molecular psychiatry 2001;6(1):92-7.
2001: M B Liddell; Simon Lovestone; Michael J Owen
Genetic risk of Alzheimer's disease: advising relatives.
The British journal of psychiatry : the journal of mental science 2001;178(1):7-11.
2000: Amanda Myers; Peter Holmans; Helen Marshall; J Kwon; David Meyer; Dzanan Ramic; Shantia Shears; Jeremy Booth; FW DeVrieze; Richard Crook; Marian Hamshere; Richard Abraham; Nigel Tunstall; Frances Rice; S Carty; S Lillystone; Pat Kehoe; Varuni Rudrasingham; Lesley Jones; Simon Lovestone; Jordi Perez-Tur; Julie Williams; Michael J Owen; John Hardy; Alison Goate
Susceptibility locus for Alzheimer's disease on chromosome 10.
Science (New York, N.Y.) 2000;290(5500):2304-5.
2000: John B Vincent; Qiu-Ping Yuan; Martin Schalling; Rolf Adolfsson; Maria H Azevedo; antonio macedo; A Bauer; C DallaTorre; Helena Medeiros; Michele T Pato; Carlos N Pato; Timothy Bowen; Carol A Guy; Michael J Owen; Michael C O'Donovan; Andrew D Paterson; Arturas Petronis; James L Kennedy
Long repeat tracts at SCA8 in major psychosis.
American journal of medical genetics 2000;96(6):873-6.
2000: Pak C Sham; Abram Sterne; Shaun Purcell; Stacey Cherny; M Webster; Frühling Rijsdijk; Philip Asherson; David Ball; Ian W Craig; Thalia C Eley; D Goldberg; J Gray; A Mann; Michael J Owen; Robert Plomin
GENESiS: creating a composite index of the vulnerability to anxiety and depression in a community-based sample of siblings.
Twin research : the official journal of the International Society for Twin Studies 2000;3(4):316-22.
2000: Timothy Bowen; L Ashworth; George Kirov; Carol A Guy; Ian Richard Jones; Fiona McCandless; Nick Craddock; Michael C O'Donovan; Michael J Owen
No evidence of association from transmission disequilibrium analysis of the hKCa3 gene in bipolar disorder.
Bipolar disorders 2000;2(4):328-31.
2000: Bastiaan Hoogendoorn; Nadine Norton; George Kirov; Nigel Williams; Marian Hamshere; Gillian Spurlock; J Austin; M K Stephens; Paul R Buckland; Michael J Owen; Michael C O'Donovan
Cheap, accurate and rapid allele frequency estimation of single nucleotide polymorphisms by primer extension and DHPLC in DNA pools.
Human genetics 2000;107(5):488-93.
2000: Lisa Anne Jones; Alastair G Cardno; Kieran C Murphy; Robert D Sanders; MY Gray; G McCarthy; Peter McGuffin; Michael J Owen; J Williams
The kings schizotypy questionnaire as a quantitative measure of schizophrenia liability.
Schizophrenia research 2000;45(3):213-21.
2000: J Austin; Paul R Buckland; Alastair G Cardno; Nigel Williams; Gillian Spurlock; Bastiaan Hoogendoorn; Stanley Zammit; G Jones; R Sanders; Lesley Jones; G McCarthy; Sue Jones; Nicholas J Bray; Peter McGuffin; Michael J Owen; Michael C O'Donovan
The high affinity neurotensin receptor gene (NTSR1): comparative sequencing and association studies in schizophrenia.
Molecular psychiatry 2000;5(5):552-7.
2000: Jane Holmes; Antony Payton; JH Barrett; Tracey Hever; Helen Fitzpatrick; Anne Trumper; Richard Harrington; Peter McGuffin; Michael J Owen; W E R Ollier; Jane Worthington; Anita Thapar
A family-based and case-control association study of the dopamine D4 receptor gene and dopamine transporter gene in attention deficit hyperactivity disorder.
Molecular psychiatry 2000;5(5):523-30.
2000: Douglas F Levinson; Peter Holmans; Richard Straub; Michael J Owen; Dieter B Wildenauer; Pablo V Gejman; Ann E Pulver; C Laurent; K S Kendler; D Walsh; Nadine Norton; Nigel M Williams; Sibylle G Schwab; Bernard Lerer; Bryan J Mowry; Alan R Sanders; Stylianos Antonarakis; Jean-Louis Blouin; Jean-François Deleuze; J Mallet
Multicenter linkage study of schizophrenia candidate regions on chromosomes 5q, 6q, 10p, and 13q: schizophrenia linkage collaborative group III.
American journal of human genetics 2000;67(3):652-63.
2000: Nicholas J Bray; Nigel M Williams; Timothy Bowen; Alastair G Cardno; Marion Gray; Lisa Anne Jones; Kieran C Murphy; Robert D Sanders; Gillian Spurlock; M C Odonovan; Michael J Owen
No evidence for association between a non-synonymous polymorphism in the gene encoding human metabotropic glutamate receptor 7 and schizophrenia.
Psychiatric genetics 2000;10(2):83-6.
2000: S Deb; J Braganza; Nadine Norton; Hywel Williams; Pat Kehoe; Julie Williams; Michael J Owen
APOE epsilon 4 influences the manifestation of Alzheimer's disease in adults with Down's syndrome.
The British journal of psychiatry : the journal of mental science 2000;176():468-72.
2000: G Speight; Darko Turic; J Austin; Bastiaan Hoogendoorn; Alastair G Cardno; Lesley Jones; Kieran C Murphy; R Sanders; G McCarthy; Ian Jones; Fiona McCandless; Peter McGuffin; Nick Craddock; Michael J Owen; Paul R Buckland; Michael C O'Donovan
Comparative sequencing and association studies of aromatic L-amino acid decarboxylase in schizophrenia and bipolar disorder.
Molecular psychiatry 2000;5(3):327-31.
2000: Erik G Jönsson; Nadine Norton; J Petter Gustavsson; L Oreland; Michael J Owen; Göran C Sedvall
A promoter polymorphism in the monoamine oxidase A gene and its relationships to monoamine metabolite concentrations in CSF of healthy volunteers.
Journal of psychiatric research 2000;34(3):239-44.
2000: Fiona Middle; Ian Jones; Fiona McCandless; Timothy Barrett; Farhat L Khanim; Michael J Owen; Corinne Lendon; Nick Craddock
Bipolar disorder and variation at a common polymorphism (A1832G) within exon 8 of the Wolfram gene.
American journal of medical genetics 2000;96(2):154-7.
2000: Derek W Morris; L Robinson; Darko Turic; M Duke; V Webb; Charis Milham; Elizabeth Hopkin; K Pound; S Fernando; M Easton; Marian Hamshere; Nigel Williams; Peter McGuffin; J Stevenson; Michael Krawczak; Michael J Owen; Michael C O'Donovan; Julie Williams
Family-based association mapping provides evidence for a gene for reading disability on chromosome 15q.
Human molecular genetics 2000;9(5):843-8.
2000: J Austin; Bastiaan Hoogendoorn; Paul R Buckland; Ian Jones; Fiona McCandless; Nigel Williams; Fiona Middle; Michael J Owen; Nick Craddock; Michael C O'Donovan
Association analysis of the proneurotensin gene and bipolar disorder.
Psychiatric genetics 2000;10(1):51-4.
2000: Timothy Bowen; Carol A Guy; Alastair G Cardno; John B Vincent; James L Kennedy; Lisa Anne Jones; Marion Gray; Robert D Sanders; G McCarthy; Kieran C Murphy; Michael J Owen; Michael C O'Donovan
Repeat sizes at CAG/CTG loci CTG18.1, ERDA1 and TGC13-7a in schizophrenia.
Psychiatric genetics 2000;10(1):33-7.
2000: J Austin; Bastiaan Hoogendoorn; Paul R Buckland; G Speight; Alastair G Cardno; Timothy Bowen; Nigel Williams; Gillian Spurlock; R Sanders; Lesley Jones; K Murphy; G McCarthy; Peter McGuffin; Michael J Owen; Michael C O'Donovan
Comparative sequencing of the proneurotensin gene and association studies in schizophrenia.
Molecular psychiatry 2000;5(2):208-12.
2000: Michael J Owen
Molecular genetic studies of schizophrenia.
Brain research. Brain research reviews 2000;31(2-3):179-86.
2000: Nigel Tunstall; Michael J Owen; Julie Williams; Frances Rice; S Carty; S Lillystone; L Fraser; Pat Kehoe; D Neill; Varuni Rudrasingham; P Sham; Simon Lovestone
Familial influence on variation in age of onset and behavioural phenotype in Alzheimer's disease.
The British journal of psychiatry : the journal of mental science 2000;176():156-9.
2000: A E Farmer; Michael J Owen; Peter McGuffin
Bioethics and genetic research in psychiatry.
The British journal of psychiatry : the journal of mental science 2000;176():105-8.
2000: Mark I Rees; P Watts; Iain Fenton; Angus Clarke; Russell G Snell; Michael J Owen; J Gray
Further evidence of autosomal dominant congenital zonular pulverulent cataracts linked to 13q11 (CZP3) and a novel mutation in connexin 46 (GJA3).
Human genetics 2000;106(2):206-9.
2000: Michael J Owen; Alastair G Cardno; Michael C O'Donovan
Psychiatric genetics: back to the future.
Molecular psychiatry 2000;5(1):22-31.
2000: George Kirov; Nigel Williams; P Sham; Nick Craddock; Michael J Owen
Pooled genotyping of microsatellite markers in parent-offspring trios.
Genome research 2000;10(1):105-15.
1999: George Kirov; Ian Jones; Fiona McCandless; Nick Craddock; Michael J Owen
Family-based association studies of bipolar disorder with candidate genes involved in dopamine neurotransmission: DBH, DAT1, COMT, DRD2, DRD3 and DRD5.
Molecular psychiatry 1999;4(6):558-65.
1999: Hywel J Williams; Nicholas J Bray; Kieran C Murphy; Alastair G Cardno; Lisa Anne Jones; Michael J Owen
No evidence for allelic association between schizophrenia and a functional variant of the human dopamine beta-hydroxylase gene (DBH).
American journal of medical genetics 1999;88(5):557-9.
1999: Timothy Bowen; George Kirov; Michael Gill; Gillian Spurlock; Homero Vallada; R M Murray; Peter McGuffin; DA Collier; Michael J Owen; Nick Craddock
Linkage studies of bipolar disorder with chromosome 18 markers.
American journal of medical genetics 1999;88(5):503-9.
1999: Kieran C Murphy; Lisa Anne Jones; Michael J Owen
High rates of schizophrenia in adults with velo-cardio-facial syndrome.
Archives of general psychiatry 1999;56(10):940-5.
1999: George Kirov; M Rees; Ian Jones; F MacCandless; Michael J Owen; Nick Craddock
Bipolar disorder and the serotonin transporter gene: a family-based association study.
Psychological medicine 1999;29(5):1249-54.
1999: Michael C O'Donovan; Michael J Owen
Candidate-gene association studies of schizophrenia.
American journal of human genetics 1999;65(3):587-92.
1999: Nigel M Williams; Mark I Rees; Peter Holmans; Nadine Norton; Alastair G Cardno; Lisa Anne Jones; Kieran C Murphy; Robert D Sanders; G McCarthy; MY Gray; Iain Fenton; Peter McGuffin; Michael J Owen
A two-stage genome scan for schizophrenia susceptibility genes in 196 affected sibling pairs.
Human molecular genetics 1999;8(9):1729-39.
1999: NJ Jacobsen; Ita Lyons; Bastiaan Hoogendoorn; S Burge; P Y Kwok; Michael C O'Donovan; Nick Craddock; Michael J Owen
ATP2A2 mutations in Darier's disease and their relationship to neuropsychiatric phenotypes.
Human molecular genetics 1999;8(9):1631-6.
1999: Carol A Guy; Timothy Bowen; Ian Jones; Fiona McCandless; Michael J Owen; Nick Craddock; Michael C O'Donovan
CTG18.1 and ERDA-1 CAG/CTG repeat size in bipolar disorder.
Neurobiology of disease 1999;6(4):302-7.
1999: Fabienne Wavrant-De Vrièze; Richard Crook; Peter Holmans; Pat Kehoe; Michael J Owen; Julie Williams; K Roehl; D K Laliiri; Shantia Shears; Jeremy Booth; W Wu; Alison Goate; Marie-Christine Chartier-Harlin; John Hardy; Jordi Pérez-Tur
Genetic variability at the amyloid-beta precursor protein locus may contribute to the risk of late-onset Alzheimer's disease.
Neuroscience letters 1999;269(2):67-70.
1999: Mark I Rees; Iain Fenton; Nigel M Williams; Peter Holmans; Nadine Norton; Alastair G Cardno; Philip Asherson; Gillian Spurlock; E Roberts; E Parfitt; R Mant; Homero Vallada; E Dawson; M W Li; DA Collier; John F Powell; S Nanko; Michael Gill; Peter McGuffin; Michael J Owen
Autosome search for schizophrenia susceptibility genes in multiply affected families.
Molecular psychiatry 1999;4(4):353-9.
1999: Michael J Owen; Alastair G Cardno
Psychiatric genetics: progress, problems, and potential.
Lancet 1999;354 Suppl 1():SI11-4.
1999: Alastair G Cardno; Timothy Bowen; Carol A Guy; Lisa Anne Jones; G McCarthy; Nigel M Williams; Kieran C Murphy; Gillian Spurlock; Marion Gray; Robert D Sanders; Nick Craddock; Peter McGuffin; Michael J Owen; Michael C O'Donovan
CAG repeat length in the hKCa3 gene and symptom dimensions in schizophrenia.
Biological psychiatry 1999;45(12):1592-6.
1999: J Williams; Pat Kehoe; Michael J Owen
Case-control study of presenelin-1 intronic polymorphism.
Journal of neurology, neurosurgery, and psychiatry 1999;66(6):702.
1999: NJ Jacobsen; EK Franks; Michael J Owen; Nick Craddock
Mutational analysis of phospholipase A2A: a positional candidate susceptibility gene for bipolar disorder.
Molecular psychiatry 1999;4(3):274-9.
1999: Varuni Rudrasingham; Fabienne Wavrant-De Vrièze; jean-charles lambert; S Chakraverty; Pat Kehoe; Richard Crook; Philippe Amouyel; W Wu; Frances Rice; Jordi Pérez-Tur; Bernard Frigard; John C Morris; S Carty; Ronald C. Petersen; Dominique Cottel; Nigel Tunstall; Peter Holmans; Simon Lovestone; Marie-Christine Chartier-Harlin; Alison Goate; John Hardy; Michael J Owen; Julie Williams
Alpha-2 macroglobulin gene and Alzheimer disease.
Nature genetics 1999;22(1):17-9; author reply 21-2.
1999: PJ Fisher; Darko Turic; Nigel M Williams; Peter McGuffin; Philip Asherson; David Ball; Ian W Craig; Thalia C Eley; Linzy Hill; Karen A Chorney; Michael J Chorney; Camilla P Benbow; David Lubinski; Robert Plomin; Michael J Owen
DNA pooling identifies QTLs on chromosome 4 for general cognitive ability in children.
Human molecular genetics 1999;8(5):915-22.
1999: Linzy Hill; Ian W Craig; Philip Asherson; David Ball; Thalia C Eley; T Ninomiya; PJ Fisher; Darko Turic; Peter McGuffin; Michael J Owen; Karen A Chorney; Michael J Chorney; Camilla P Benbow; David Lubinski; Lee A Thompson; Robert Plomin
DNA pooling and dense marker maps: a systematic search for genes for cognitive ability.
Neuroreport 1999;10(4):843-8.
1999: F Wavrant-DeVrièze; Varuni Rudrasingham; jean-charles lambert; S Chakraverty; Pat Kehoe; Richard Crook; Philippe Amouyel; W Wu; Peter Holmans; Frances Rice; Jordi Pérez-Tur; Bernard Frigard; John C Morris; S Carty; Dominique Cottel; Nigel Tunstall; Simon Lovestone; Ronald C. Petersen; Marie-Christine Chartier-Harlin; Alison Goate; Michael J Owen; Julie Williams; John Hardy
No association between the alpha-2 macroglobulin I1000V polymorphism and Alzheimer's disease.
Neuroscience letters 1999;262(2):137-9.
1999: EK Franks; Carol Guy; N Jacobsen; Timothy Bowen; Michael J Owen; Michael C O'Donovan; Nick Craddock
Eleven trinucleotide repeat loci that map to chromosome 12 excluded from involvement in the pathogenesis of bipolar disorder.
American journal of medical genetics 1999;88(1):67-70.
1999: Carol A Guy; Timothy Bowen; Nigel Williams; Ian Richard Jones; Fiona McCandless; Peter McGuffin; Michael J Owen; Nick Craddock; Michael C O'Donovan
No association between a polymorphic CAG repeat in the human potassium channel gene hKCa3 and bipolar disorder.
American journal of medical genetics 1999;88(1):57-60.
1999: Pat Kehoe; M Krawczak; Peter S Harper; Michael J Owen; AL Jones
Age of onset in Huntington disease: sex specific influence of apolipoprotein E genotype and normal CAG repeat length.
Journal of medical genetics 1999;36(2):108-11.
1999: Pat Kehoe; Fabienne Wavrant De-Vrieze; Richard Crook; W S Wu; Peter Holmans; Iain Fenton; Gillian Spurlock; Nadine Norton; Hywel Williams; Nigel Williams; Simon Lovestone; Jordi Perez-Tur; Michael Hutton; Marie-Christine Chartier-Harlin; Shantia Shears; K Roehl; Jeremy Booth; W Van Voorst; Dzanan Ramic; Julie Williams; Alison Goate; John Hardy; Michael J Owen
A full genome scan for late onset Alzheimer's disease.
Human molecular genetics 1999;8(2):237-45.
1999: Alastair G Cardno; Lisa Anne Jones; Kieran C Murphy; Robert D Sanders; Philip Asherson; Michael J Owen; Peter McGuffin
Dimensions of psychosis in affected sibling pairs.
Schizophrenia bulletin 1999;25(4):841-50.
1999: Bastiaan Hoogendoorn; Michael J Owen; PJ Oefner; Nigel Williams; J Austin; Michael C O'Donovan
Genotyping single nucleotide polymorphisms by primer extension and high performance liquid chromatography.
Human genetics 1999;104(1):89-93.
1999: Pat Kehoe; C Russ; S McIlory; H Williams; Peter Holmans; C Holmes; D Liolitsa; D Vahidassr; J Powell; B McGleenon; M Liddell; Robert Plomin; Kevin B Dynan; N Williams; Jim Neal; Nigel J Cairns; Gordon K Wilcock; Peter Passmore; Simon Lovestone; Julie Williams; Michael J Owen
Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease.
Nature genetics 1999;21(1):71-2.
1999: George Kirov; Michael J Owen; Ian Jones; Fiona McCandless; Nick Craddock
Tryptophan hydroxylase gene and manic-depressive illness.
Archives of general psychiatry 1999;56(1):98-9.
1998: Pat Kehoe; Hywel Williams; Peter Holmans; Gordon K Wilcock; Nigel J Cairns; Jim Neal; Michael J Owen
The butyrylcholinesterase K variant and susceptibility to Alzheimer's disease.
Journal of medical genetics 1998;35(12):1034-5.
1998: W S Wu; Peter Holmans; F Wavrant-DeVrièze; Shantia Shears; Pat Kehoe; Richard Crook; Jeremy Booth; Nigel Williams; Jordi Pérez-Tur; K Roehl; Iain Fenton; Marie-Christine Chartier-Harlin; Simon Lovestone; Julie Williams; Michael Hutton; John Hardy; Michael J Owen; Alison Goate
Genetic studies on chromosome 12 in late-onset Alzheimer disease.
JAMA : the journal of the American Medical Association 1998;280(7):619-22.
1998: P Wright; E Dawson; Peter T Donaldson; James Underhill; Pak C Sham; J Zhao; Mike Gill; Shinichiro Nanko; Michael J Owen; Peter McGuffin; Robin M Murray
A transmission/disequilibrium study of the DRB1*04 gene locus on chromosome 6p21.3 with schizophrenia.
Schizophrenia research 1998;32(2):75-80.
1998: Alastair G Cardno; Lisa Anne Jones; Kieran C Murphy; Robert D Sanders; Philip Asherson; Michael J Owen; Peter McGuffin
Sibling pairs with schizophrenia or schizoaffective disorder: associations of subtypes, symptoms and demographic variables.
Psychological medicine 1998;28(4):815-23.
1998: George Kirov; Kieran C Murphy; M J Arranz; Ian Jones; F McCandles; H Kunugi; R M Murray; Peter McGuffin; DA Collier; Michael J Owen; Nick Craddock
Low activity allele of catechol-O-methyltransferase gene associated with rapid cycling bipolar disorder.
Molecular psychiatry 1998;3(4):342-5.
1998: Philip Asherson; R Mant; Nigel Williams; Alastair G Cardno; Lesley Jones; K Murphy; DA Collier; S Nanko; Nick Craddock; S Morris; Walter Muir; B Blackwood; Peter McGuffin; Michael J Owen
A study of chromosome 4p markers and dopamine D5 receptor gene in schizophrenia and bipolar disorder.
Molecular psychiatry 1998;3(4):310-20.
1998: Timothy Bowen; Carol A Guy; Nick Craddock; Alastair G Cardno; Nigel M Williams; Gillian Spurlock; Kieran C Murphy; Lisa Anne Jones; Marion Gray; Robert D Sanders; G McCarthy; K George Chandy; Emmanuelle Fantino; Katalin Kalman; George A Gutman; J Jay Gargus; Julie Williams; Peter McGuffin; Michael J Owen; Michael C O'Donovan
Further support for an association between a polymorphic CAG repeat in the hKCa3 gene and schizophrenia.
Molecular psychiatry 1998;3(3):266-9.
1998: J Daniels; Peter Holmans; N Williams; Darko Turic; Peter McGuffin; Robert Plomin; Michael J Owen
A simple method for analyzing microsatellite allele image patterns generated from DNA pools and its application to allelic association studies.
American journal of human genetics 1998;62(5):1189-97.
1998: J Daniels; Peter McGuffin; Michael J Owen; Robert Plomin
Molecular genetic studies of cognitive ability.
Human biology 1998;70(2):281-96.
1998: Julie Williams; Gillian Spurlock; Peter Holmans; R Mant; K Murphy; Lesley Jones; Alastair G Cardno; Philip Asherson; D H R Blackwood; Walter Muir; Kurt Meszaros; Harald N Aschauer; J Mallet; C Laurent; P Pekkarinen; J Seppala; Costas N Stefanis; George N Papadimitriou; Fabio Macciardi; M Verga; C Pato; H Azevedo; M A Crocq; Hugh M D Gurling; Michael J Owen
A meta-analysis and transmission disequilibrium study of association between the dopamine D3 receptor gene and schizophrenia.
Molecular psychiatry 1998;3(2):141-9.
1998: Gillian Spurlock; Julie Williams; Peter McGuffin; Harald N Aschauer; Elisabeth Lenzinger; Karoline Fuchs; Werner Sieghart; Kurt Meszaros; Nahid Fathi; C Laurent; J Mallet; Fabio Macciardi; S Pedrini; Michael Gill; Ziarih Hawi; S Gibson; Elena Jazin; H T Yang; Rolf Adolfsson; C N Pato; Ana Dourado; Michael J Owen
European Multicentre Association Study of Schizophrenia: a study of the DRD2 Ser311Cys and DRD3 Ser9Gly polymorphisms.
American journal of medical genetics 1998;81(1):24-8.
1998: Alastair G Cardno; Kieran C Murphy; Lisa Anne Jones; A M Cobb; Jonathon Gray; Peter McGuffin; Michael J Owen
Polydactyly and psychosis. Five cases of co-occurrence.
The British journal of psychiatry : the journal of mental science 1998;172():184-5.
1998: Kieran C Murphy; R G Jones; E Griffiths; P W Thompson; Michael J Owen
Chromosome 22qII deletions. An under-recognised cause of idiopathic learning disability.
The British journal of psychiatry : the journal of mental science 1998;172():180-3.
1998: David Ball; Linzy Hill; Thalia C Eley; Michael J Chorney; Karen A Chorney; Lee A Thompson; Douglas K Detterman; Camilla P Benbow; David Lubinski; Michael J Owen; Peter McGuffin; Robert Plomin
Dopamine markers and general cognitive ability.
Neuroreport 1998;9(2):347-9.
1998: Homero Vallada; L Vasques; D Curtis; Mayana Zatz; G Kirov; V Lauriano; Valentim Gentil; Robin M Murray; Peter McGuffin; Michael J Owen; Mike Gill; N Craddock; David A Collier
Linkage analysis between bipolar affective disorder and markers on chromosome X.
Psychiatric genetics 1998;8(3):183-6.
1998: Michael J Owen; Nick Craddock
Chromosome 11 workshop.
Psychiatric genetics 1998;8(2):89-92.
1998: Alastair G Cardno; Fiona McCandless; Timothy Bowen; Carol A Guy; Lisa Anne Jones; Kieran C Murphy; Peter McGuffin; Michael J Owen; Nick Craddock; Michael C O'Donovan
Association between functional psychosis and expanded CAG/CTG repeats is not explained by health stratification.
Psychiatric genetics 1998;8(1):29-32.
1998: Timothy Bowen; Nadine Norton; NJ Jacobsen; Carol Guy; johanna k macpherson; Robert D Sanders; Alastair G Cardno; Lisa Anne Jones; Kieran C Murphy; Peter McGuffin; Nick Craddock; Michael C O'Donovan; Michael J Owen
Linked polymorphisms upstream of exons 1 and 2 of the human cholecystokinin gene are not associated with schizophrenia or bipolar disorder.
Molecular psychiatry 1998;3(1):67-71.
1998: Maria J Arranz; Janet Munro; Michael J Owen; Gillian Spurlock; Pak C Sham; J Zhao; G Kirov; David A Collier; Robert W Kerwin
Evidence for association between polymorphisms in the promoter and coding regions of the 5-HT2A receptor gene and response to clozapine.
Molecular psychiatry 1998;3(1):61-6.
1998: Gillian Spurlock; A Heils; Peter Holmans; Julie Williams; UM D'Souza; Alastair G Cardno; Kieran C Murphy; Lesley Jones; Paul R Buckland; Peter McGuffin; K P Lesch; Michael J Owen
A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter.
Molecular psychiatry 1998;3(1):42-9.
1997: Nick Craddock; Patrick McKeon; S Moorhead; Carol Guy; D Harrison; Lesley Mynett-Johnson; E Claffey; E Feldman; Peter McGuffin; Michael J Owen; Michael C O'Donovan
Expanded CAG/CTG repeats in bipolar disorder: no correlation with phenotypic measures of illness severity.
Biological psychiatry 1997;42(10):876-81.
1997: AL Jones; Fiona Middle; Carol Guy; Gillian Spurlock; Nigel J Cairns; Peter McGuffin; Nick Craddock; Michael J Owen; Michael C O'Donovan
No evidence for expanded polyglutamine sequences in bipolar disorder and schizophrenia.
Molecular psychiatry 1997;2(6):478-82.
1997: Michael J Owen; Peter McGuffin
Genetics and psychiatry.
The British journal of psychiatry : the journal of mental science 1997;171():201-2.
1997: M Rees; Nadine Norton; Ian Jones; Fiona McCandless; Jane Scourfield; Peter Holmans; S Moorhead; E Feldman; Stephanie Sadler; T Cole; Kate Redman; Anne Farmer; Peter McGuffin; Michael J Owen; Nick Craddock
Association studies of bipolar disorder at the human serotonin transporter gene (hSERT; 5HTT).
Molecular psychiatry 1997;2(5):398-402.
1997: Carol Guy; Timothy Bowen; johanna k macpherson; G Speight; Patrick McKeon; Lesley Mynett-Johnson; E Claffey; Peter McGuffin; Michael J Owen; Nick Craddock; Michael C O'Donovan
Exclusion of expansion of 50 CAG/CTG trinucleotide repeats in bipolar disorder.
The American journal of psychiatry 1997;154(8):1146-7.
1997: Michael J Owen; P Holmans; Peter McGuffin
Association studies in psychiatric genetics.
Molecular psychiatry 1997;2(4):270-3.
1997: johanna k macpherson; Gillian Spurlock; Nigel M Williams; Alastair G Cardno; Lisa Anne Jones; Kieran C Murphy; Philip Asherson; Peter Holmans; Iain Fenton; Peter McGuffin; Michael J Owen
Linkage study of chromosome 6p in sib-pairs with schizophrenia.
American journal of medical genetics 1997;74(3):319-23.
1997: J Williams; Peter McGuffin; M Nöthen; Michael J Owen
Meta-analysis of association between the 5-HT2a receptor T102C polymorphism and schizophrenia. EMASS Collaborative Group. European Multicentre Association Study of Schizophrenia.
Lancet 1997;349(9060):1221.
1997: G Speight; Carol Guy; Timothy Bowen; Philip Asherson; Peter McGuffin; Nick Craddock; Michael J Owen; Michael C O'Donovan
Exclusion of CAG/CTG trinucleotide repeat loci which map to chromosome 4 in bipolar disorder and schizophrenia.
American journal of medical genetics 1997;74(2):204-6.
1997: Alastair G Cardno; Peter Holmans; I Harvey; M B Williams; Michael J Owen; Peter McGuffin
Factor-derived subsyndromes of schizophrenia and familial morbid risks.
Schizophrenia research 1997;23(3):231-8.
1997: Nigel M Williams; Lisa Anne Jones; Kieran C Murphy; Alastair G Cardno; Philip Asherson; Julie Williams; Peter McGuffin; Michael J Owen
No evidence for an allelic association between schizophrenia and markers D22S278 and D22S283.
American journal of medical genetics 1997;74(1):37-9.
1997: M Andrew; Michael J Owen
Hyperekplexia: abnormal startle response due to glycine receptor mutations.
The British journal of psychiatry : the journal of mental science 1997;170():106-8.
1997: Erik G Jönsson; David Goldman; G Spurlock; J Petter Gustavsson; DA Nielsen; Markku Linnoila; Michael J Owen; Göran C Sedvall
Tryptophan hydroxylase and catechol-O-methyltransferase gene polymorphisms: relationships to monoamine metabolite concentrations in CSF of healthy volunteers.
European archives of psychiatry and clinical neuroscience 1997;247(6):297-302.
1997: Hiroshi Kunugi; Homero Vallada; Pak C Sham; F Hoda; Maria J Arranz; T Li; Shinichiro Nanko; Robin M Murray; Peter McGuffin; Michael J Owen; Mike Gill; David A Collier
Catechol-O-methyltransferase polymorphisms and schizophrenia: a transmission disequilibrium study in multiply affected families.
Psychiatric genetics 1997;7(3):97-101.
1997: Nigel M Williams; Alastair G Cardno; Kieran C Murphy; Lisa Anne Jones; Philip Asherson; Peter McGuffin; Michael J Owen
Association between schizophrenia and a microsatellite polymorphism at the dopamine D5 receptor gene.
Psychiatric genetics 1997;7(2):83-5.
1997: Stephen A Petrill; Robert Plomin; Gerald E McClearn; D L Smith; S Vignetti; Michael J Chorney; Karen A Chorney; Lee A Thompson; Douglas K Detterman; Camilla P Benbow; David Lubinski; J Daniels; Michael J Owen; Peter McGuffin
No association between general cognitive ability and the A1 allele of the D2 dopamine receptor gene.
Behavior genetics 1997;27(1):29-31.
1996: Nick Craddock; Michael C O'Donovan; Michael J Owen
Introducing Selfcite 2.0--career enhancing software.
BMJ (Clinical research ed.) 1996;313(7072):1659-60.
1996: Michael C O'Donovan; Nick Craddock; Carol Guy; Peter McGuffin; Michael J Owen
Involvement of expanded trinucleotide repeats in common diseases.
Lancet 1996;348(9043):1739-40.
1996: Homero Vallada; Nick Craddock; L Vasques; D Curtis; George Kirov; V Lauriano; Valentim Gentil; R Passos-Bueno; Robin M Murray; Mayana Zatz; Peter McGuffin; John F Powell; M Gill; Michael J Owen; D A Collier
Linkage studies in bipolar affective disorder with markers on chromosome 21.
Journal of affective disorders 1996;41(3):217-21.
1996: Alastair G Cardno; Lisa Anne Jones; Kieran C Murphy; Philip Asherson; L C Scott; J Williams; Michael J Owen; Peter McGuffin
Factor analysis of schizophrenic symptoms using the OPCRIT checklist.
Schizophrenia research 1996;22(3):233-9.
1996: Michael C O'Donovan; Michael J Owen
The molecular genetics of schizophrenia.
Annals of medicine 1996;28(6):541-6.
1996: Alastair G Cardno; Kieran C Murphy; Lisa Anne Jones; Carol A Guy; Philip Asherson; M H De Azevedo; Isabel Coelho; A J de Macedo e Santos; C N Pato; Peter McGuffin; Michael J Owen; Michael C O'Donovan
Expanded CAG/CTG repeats in schizophrenia. A study of clinical correlates.
The British journal of psychiatry : the journal of mental science 1996;169(6):766-71.
1996: Michael C O'Donovan; Carol Guy; Nick Craddock; Timothy Bowen; Patrick McKeon; antonio macedo; W Maier; D Wildenauer; Harald N Aschauer; Sandro Sorbi; E Feldman; Lesley Mynett-Johnson; E Claffey; Benedetta Nacmias; José Valente; Ana Dourado; E Grassi; Elisabeth Lenzinger; Angela Heiden; S Moorhead; D Harrison; Julie Williams; Peter McGuffin; Michael J Owen
Confirmation of association between expanded CAG/CTG repeats and both schizophrenia and bipolar disorder.
Psychological medicine 1996;26(6):1145-53.
1996: Hiroshi Kunugi; D Curtis; Homero Vallada; Shinichiro Nanko; John F Powell; Robin M Murray; Peter McGuffin; Michael J Owen; M Gill; D A Collier
A linkage study of schizophrenia with DNA markers from chromosome 8p21-p22 in 25 multiplex families.
Schizophrenia research 1996;22(1):61-8.
1996: J Daniels; Peter McGuffin; Michael J Owen
Molecular genetic research on IQ: can it be done? Should it be done?
Journal of biosocial science 1996;28(4):491-507.
1996: Timothy Bowen; Carol Guy; G Speight; L Jones; Alastair G Cardno; K Murphy; Peter McGuffin; Michael J Owen; Michael C O'Donovan
Expansion of 50 CAG/CTG repeats excluded in schizophrenia by application of a highly efficient approach using repeat expansion detection and a PCR screening set.
American journal of human genetics 1996;59(4):912-7.
1996: Pat Kehoe; Julie Williams; Peter Holmans; M Liddell; Simon Lovestone; C Holmes; J Powell; Jim Neal; Gordon K Wilcock; Michael J Owen
Association between a PS-1 intronic polymorphism and late onset Alzheimer's disease.
Neuroreport 1996;7(13):2155-8.
1996: Michael J Owen; Pat Kehoe; J Williams
Presenilin-1 polymorphism and Alzheimer's disease.
Lancet 1996;348(9024):414.
1996: A Farmer; Michael J Owen
Genomics: the next psychiatric revolution?
The British journal of psychiatry : the journal of mental science 1996;169(2):135-8.
1996: N Craddock; Michael J Owen
Modern molecular genetic approaches to psychiatric disease.
British medical bulletin 1996;52(3):434-52.
1996: M Craddock; Philip Asherson; Michael J Owen; J Williams; Peter McGuffin; A E Farmer
Concurrent validity of the OPCRIT diagnostic system. Comparison of OPCRIT diagnoses with consensus best-estimate lifetime diagnoses.
The British journal of psychiatry : the journal of mental science 1996;169(1):58-63.
1996: E Parfitt; Philip Asherson; E Roberts; R Mant; Shinichiro Nanko; M Gill; Peter McGuffin; Michael J Owen
No evidence for linkage between schizophrenia and eight microsatellite markers on chromosome 19.
Human heredity 1996;46(4):191-6.
1996: Julie Williams; Gillian Spurlock; Peter McGuffin; J Mallet; M M Nöthen; M Gill; Harald N Aschauer; Per-Olof Nylander; Fabio Macciardi; Michael J Owen
Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene. European Multicentre Association Study of Schizophrenia (EMASS) Group.
Lancet 1996;347(9011):1294-6.
1996: Philip Asherson; R Mant; Peter Holmans; Julie Williams; Alastair G Cardno; K Murphy; Lesley Jones; David Collier; Peter McGuffin; Michael J Owen
Linkage, association and mutational analysis of the dopamine D3 receptor gene in schizophrenia.
Molecular psychiatry 1996;1(2):125-32.
1996: Pat Kehoe; Julie Williams; Simon Lovestone; Gordon K Wilcock; Michael J Owen
Presenilin-1 polymorphism and Alzheimer's disease. The UK Alzheimer's Disease Collaborative Group.
Lancet 1996;347(9009):1185.
1996: K C Murphy; Michael J Owen
Schizophrenia, CATCH 22 and FISH.
The British journal of psychiatry : the journal of mental science 1996;168(4):397-8.
1996: Nick Craddock; J Daniels; Peter Holmans; Nigel Williams; Michael J Owen
Increasing the efficiency of genomic searches for linkage in complex disorders by DNA pooling of affected sib-pairs.
Molecular psychiatry 1996;1(1):59-64.
1996: Michael J Owen; Nick Craddock
Modern molecular genetic approaches to complex traits: implications for psychiatric disorders.
Molecular psychiatry 1996;1(1):21-6.
1996: L C Lim; Nick Craddock; Michael J Owen; Pak Sham; Markus M Nöthen; J Körner; Marcella Rietschel; R Fimmer; P Propping; Peter McGuffin; Robin Murray; M Gill
Assessing the statistical power to detect linkage in a sample of 51 bipolar affective disorder pedigrees.
Behavior genetics 1996;26(2):113-22.
1996: M Gill; Homero Vallada; David Collier; Pak Sham; Peter Holmans; Robin Murray; Peter McGuffin; Shinichiro Nanko; Michael J Owen; S Antonarakis; D Housman; Haig Kazazian ; Gerald Nestadt; Ann E Pulver; R E Straub; C J MacLean; D Walsh; K S Kendler; L DeLisi; Mihael H Polymeropoulos; Hilary Coon; William Byerley; R Lofthouse; E Gershon; C M Read
A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22).
American journal of medical genetics 1996;67(1):40-5.
1996: K C Murphy; Michael J Owen
Minor physical anomalies and their relationship to the aetiology of schizophrenia.
The British journal of psychiatry : the journal of mental science 1996;168(2):139-42.
1996: johanna k macpherson; Nigel M Williams; Julie Williams; Lisa Anne Jones; Alastair G Cardno; Kieran C Murphy; Gillian Spurlock; B Riley; P Scambler; Philip Asherson; Peter McGuffin; Michael J Owen
No evidence for allelic association between schizophrenia and a polymorphism determining high or low catechol O-methyltransferase activity.
The American journal of psychiatry 1996;153(2):268-70.
1996: Peter McGuffin; Michael J Owen
Molecular genetic studies of schizophrenia.
Cold Spring Harbor symposia on quantitative biology 1996;61():815-22.
1996: N Jacobsen; J Daniels; S Moorhead; D Harrison; E Feldman; Peter McGuffin; Michael J Owen; Nick Craddock
Association study of bipolar disorder at the phospholipase A2 gene (PLA2A) in the Darier's disease (DAR) region of chromosome 12q23-q24.1.
Psychiatric genetics 1996;6(4):195-9.
1996: A Ashworth; I Abusaad; C Walsh; S Nanko; R M Murray; Philip Asherson; Peter McGuffin; M Gill; Michael J Owen; D A Collier
Linkage analysis of the fragile X gene FMR-1 and schizophrenia: no evidence for linkage but report of a family with schizophrenia and an unstable triplet repeat.
Psychiatric genetics 1996;6(2):81-6.
1995: Andrew G Roberts; Sharon D Whatley; J Daniels; Peter Holmans; Iain Fenton; Michael J Owen; P Thompson; C Long; George H Elder
Partial characterization and assignment of the gene for protoporphyrinogen oxidase and variegate porphyria to human chromosome 1q23.
Human molecular genetics 1995;4(12):2387-90.
1995: C Okoro; R Bell; Pak Sham; Shinichiro Nanko; Philip Asherson; Michael J Owen; M Gill; Peter McGuffin; Robin M Murray; David Collier
No evidence for linkage between the X-chromosome marker DXS7 and schizophrenia.
American journal of medical genetics 1995;60(5):461-4.
1995: Maria J Arranz; Tonmoy Sharma; Pak Sham; Robert Kerwin; Shinichiro Nanko; Michael J Owen; M Gill; David Collier
Schizophrenia and the androgen receptor gene: report of a sibship showing co-segregation with Reifenstein syndrome but no evidence for linkage in 23 multiply affected families.
American journal of medical genetics 1995;60(5):377-81.
1995: Peter McGuffin; Michael J Owen; A E Farmer
Genetic basis of schizophrenia.
Lancet 1995;346(8976):678-82.
1995: Nick Craddock; J Daniels; E Roberts; M Rees; Peter McGuffin; Michael J Owen
No evidence for allelic association between bipolar disorder and monoamine oxidase A gene polymorphisms.
American journal of medical genetics 1995;60(4):322-4.
1995: Michael C O'Donovan; C Guy; N Craddock; Kieran C Murphy; Alastair G Cardno; L A Jones; Michael J Owen; Peter McGuffin
Expanded CAG repeats in schizophrenia and bipolar disorder.
Nature genetics 1995;10(4):380-1.
1995: M B Liddell; A J Bayer; Michael J Owen
No evidence that common allelic variation in the Amyloid Precursor Protein (APP) gene confers susceptibility to Alzheimer's disease.
Human molecular genetics 1995;4(5):853-8.
1995: Homero Vallada; M Gill; Pak Sham; L C Lim; Shinichiro Nanko; Philip Asherson; Robin M Murray; Peter McGuffin; Michael J Owen; David Collier
Linkage studies on chromosome 22 in familial schizophrenia.
American journal of medical genetics 1995;60(2):139-46.
1995: J Daniels; Julie Williams; Philip Asherson; Peter McGuffin; Michael J Owen
No association between schizophrenia and polymorphisms within the genes for debrisoquine 4-hydroxylase (CYP2D6) and the dopamine transporter (DAT).
American journal of medical genetics 1995;60(1):85-7.
1995: Michael Mullan; C Bennett; C Figueredo; D Hughes; R Mant; Michael J Owen; AC Warren; Melvin G McInnis; A Marshall; P Lantos
Clinical features of early onset, familial Alzheimer's disease linked to chromosome 14.
American journal of medical genetics 1995;60(1):44-52.
1995: Homero Vallada; D Curtis; Pak C Sham; Robin M Murray; Peter McGuffin; Shinichiro Nanko; M Gill; Michael J Owen; D A Collier
Chromosome 22 markers demonstrate transmission disequilibrium with schizophrenia.
Psychiatric genetics 1995;5(3):127-30.
1995: M W Lin; D Curtis; N Williams; Maria J Arranz; S Nanko; David Collier; Peter McGuffin; Robin Murray; Michael J Owen; M Gill
Suggestive evidence for linkage of schizophrenia to markers on chromosome 13q14.1-q32.
Psychiatric genetics 1995;5(3):117-26.
1995: Nick Craddock; Q Roberts; N Williams; Peter McGuffin; Michael J Owen
Association study of bipolar disorder using a functional polymorphism (Ser311-->Cys) in the dopamine D2 receptor gene.
Psychiatric genetics 1995;5(2):63-5.
1994: Mark I Rees; M Andrew; S Jawad; Michael J Owen
Evidence for recessive as well as dominant forms of startle disease (hyperekplexia) caused by mutations in the alpha 1 subunit of the inhibitory glycine receptor.
Human molecular genetics 1994;3(12):2175-9.
1994: Nick Craddock; Michael J Owen
Is there an inverse relationship between Down's syndrome and bipolar affective disorder? Literature review and genetic implications.
Journal of intellectual disability research : JIDR 1994;38 ( Pt 6)():613-20.
1994: J Daniels; Julie Williams; R Mant; Philip Asherson; Peter McGuffin; Michael J Owen
Repeat length variation in the dopamine D4 receptor gene shows no evidence of association with schizophrenia.
American journal of medical genetics 1994;54(3):256-8.
1994: N Craddock; Peter McGuffin; Michael J Owen
Darier's disease cosegregating with affective disorder.
The British journal of psychiatry : the journal of mental science 1994;165(2):272.
1994: Robert Plomin; Michael J Owen; Peter McGuffin
The genetic basis of complex human behaviors.
Science (New York, N.Y.) 1994;264(5166):1733-9.
1994: Nick Craddock; J Daniels; Peter McGuffin; Michael J Owen
Variation at the fragile X locus does not influence susceptibility to bipolar disorder.
American journal of medical genetics 1994;54(2):141-3.
1994: A Thapar; Irving Gottesman; Michael J Owen; Michael C O'Donovan; Peter McGuffin
The genetics of mental retardation.
The British journal of psychiatry : the journal of mental science 1994;164(6):747-58.
1994: Philip Asherson; C Walsh; J Williams; M Sargeant; C Taylor; A Clements; M Gill; Michael J Owen; Peter McGuffin
Imprinting and anticipation. Are they relevant to genetic studies of schizophrenia?
The British journal of psychiatry : the journal of mental science 1994;164(5):619-24.
1994: Peter McGuffin; Philip Asherson; Michael J Owen; A Farmer
The strength of the genetic effect. Is there room for an environmental influence in the aetiology of schizophrenia?
The British journal of psychiatry : the journal of mental science 1994;164(5):593-9.
1994: Philip Asherson; N Williams; E Roberts; M McGuffin; Michael J Owen
DRD2 Ser311/Cys311 polymorphism in schizophrenia.
Lancet 1994;343(8904):1045.
1994: Nick Craddock; Michael J Owen
Chromosomal aberrations and bipolar affective disorder.
The British journal of psychiatry : the journal of mental science 1994;164(4):507-12.
1994: S Shaikh; M Gill; Michael J Owen; Philip Asherson; Peter McGuffin; Shinichiro Nanko; R M Murray; D A Collier
Failure to find linkage between a functional polymorphism in the dopamine D4 receptor gene and schizophrenia.
American journal of medical genetics 1994;54(1):8-11.
1994: R Mant; Julie Williams; Philip Asherson; E Parfitt; Peter McGuffin; Michael J Owen
Relationship between homozygosity at the dopamine D3 receptor gene and schizophrenia.
American journal of medical genetics 1994;54(1):21-6.
1994: Michael J Owen; M Liddell; Peter McGuffin
Alzheimer's disease.
BMJ (Clinical research ed.) 1994;308(6930):672-3.
1994: Nick Craddock; I Brockington; R Mant; E Parfitt; Peter McGuffin; Michael J Owen
Bipolar affective puerperal psychosis associated with consanguinity.
The British journal of psychiatry : the journal of mental science 1994;164(3):359-64.
1994: Nick Craddock; Michael J Owen; S Burge; B Kurian; P Thomas; Peter McGuffin
Familial cosegregation of major affective disorder and Darier's disease (keratosis follicularis)
The British journal of psychiatry : the journal of mental science 1994;164(3):355-8.
1994: M Liddell; Julie Williams; A Bayer; F Kaiser; Michael J Owen
Confirmation of association between the e4 allele of apolipoprotein E and Alzheimer's disease.
Journal of medical genetics 1994;31(3):197-200.
1994: Philip Asherson; Michael J Owen
Anticipation in mental illness.
American journal of human genetics 1994;54(2):386-7.
1994: Michael J Owen
The molecular genetics of Alzheimer's disease.
Molecular and cell biology of human diseases series 1994;4():92-109.
1994: J Körner; Marcella Rietschel; N Hunt; D Castle; M Gill; Markus M Nöthen; Nick Craddock; J Daniels; Michael J Owen; Rolf Fimmers
Association and haplotype analysis at the tyrosine hydroxylase locus in a combined German-British sample of manic depressive patients and controls.
Psychiatric genetics 1994;4(3):167-75.
1994: E Parfitt; S Burge; Nick Craddock; E Roberts; W H Irwin McLean; J Weissenbach; Peter McGuffin; Michael J Owen
The gene for Darier's disease maps between D12S78 and D12S79.
Human molecular genetics 1994;3(1):35-8.
1993: Michael J Owen; Peter McGuffin
Association and linkage: complementary strategies for complex disorders.
Journal of medical genetics 1993;30(8):638-9.
1993: S Shaikh; D Ball; Nick Craddock; D Castle; N Hunt; R Mant; Michael J Owen; David Collier; M Gill
The dopamine D3 receptor gene: no association with bipolar affective disorder.
Journal of medical genetics 1993;30(4):308-9.
1993: P B Jones; Michael J Owen; Shon Lewis; Robin M Murray
A case-control study of family history and cerebral cortical abnormalities in schizophrenia.
Acta psychiatrica Scandinavica 1993;87(1):6-12.
1993: Nick Craddock; S Burge; L Parfitt; Michael J Owen
Linkage is excluded between Darier's disease and the Duffy blood group locus in five British families.
Annales de génétique 1993;36(4):211-3.
1992: M Liddell; Michael J Owen
Role of amyloid beta-protein in Alzheimer's disease.
Lancet 1992;340(8823):851.
1992: Michael J Owen; Peter McGuffin
The molecular genetics of schizophrenia.
BMJ (Clinical research ed.) 1992;305(6855):664-5.
1992: Michael J Owen; R Mant; E Parfitt; Julie Williams; Philip Asherson; G O'Mahoney; Jim van Os; David H Llewellyn; David Collier; M Gill
No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia.
Human genetics 1992;90(1-2):131-2.
1992: R Mant; Philip Asherson; M Gill; Peter McGuffin; Michael J Owen; Susan E Wert; R J Gregory; A E Smith; J A Cohn; J M Wilson
Schizophrenia scepticism.
Nature genetics 1992;2(1):12.
1992: Homero Vallada; David Collier; E Dawson; Michael J Owen; S Nanko; R Murray; M Gill
Debrisoquine 4-hydroxylase (CYP2D) locus and possible susceptibility to schizophrenia.
Lancet 1992;340(8812):181-2.
1992: Philip Asherson; E Parfitt; M Sargeant; S Tidmarsh; Paul R Buckland; C Taylor; A Clements; M Gill; Peter McGuffin; Michael J Owen
No evidence for a pseudoautosomal locus for schizophrenia. Linkage analysis of multiply affected families.
The British journal of psychiatry : the journal of mental science 1992;161():63-8.
1992: Michael C O'Donovan; Michael J Owen
Advances and retreats in the molecular genetics of major mental illness.
Annals of medicine 1992;24(3):171-7.
1992: Michael J Owen
Will schizophrenia become a graveyard for molecular geneticists?
Psychological medicine 1992;22(2):289-93.
1992: Shinichiro Nanko; M Gill; Michael J Owen; N Takazawa; J Moridaira; H Kazamatsuri
Linkage study of schizophrenia with markers on chromosome 11 in two Japanese pedigrees.
The Japanese journal of psychiatry and neurology 1992;46(1):155-9.
1992: Michael J Owen; M Gill
Looking for genes in schizophrenia.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():222A-223A.
1991: Michael J Owen; Alison Goate; John Hardy
A polymorphic microsatellite repeat sequence on chromosome 21 (D21S80).
Nucleic acids research 1991;19(16):4574.
1991: A Foerster; Shon Lewis; Michael J Owen; R M Murray
Low birth weight and a family history of schizophrenia predict poor premorbid functioning in psychosis.
Schizophrenia research 1991;5(1):13-20.
1991: Michael J Owen; Peter McGuffin
DNA and classical genetic markers in schizophrenia.
European archives of psychiatry and clinical neuroscience 1991;240(3):197-203.
1991: Peter McGuffin; Michael J Owen
The molecular genetics of schizophrenia: an overview and forward view.
European archives of psychiatry and clinical neuroscience 1991;240(3):169-73.
1991: Michael Mullan; L Giuffra; John Hardy; I Ovenstone; A R Haynes; L A James; R Williamson; P J Newton; Michael J Owen; P Roques
Clinical and pathologic features of chromosome 21-linked familial Alzheimer's disease.
Annals of the New York Academy of Sciences 1991;640():177-80.
1990: Peter St George-Hyslop; Jonathan L Haines; Lindsay A Farrer; R Polinsky; Christine Van Broeckhoven; Alison Goate; D R McLachlan; H Orr; A C Bruni; Sandro Sorbi; I Rainero; J F Foncin; D Pollen; J M Cantu; R Tupler; N Voskresenskaya; Richard Mayeux; J Growden; V A Fried; Richard H Myers; L Nee; H Backhovens; J J Martin; Martin N Rossor; Michael J Owen; Michael Mullan; M E Percy; H Karlinsky; S Rich; L Heston; M Montesi; M Mortilla; N Nacmias; James Gusella; John Hardy
Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder.
Nature 1990;347(6289):194-7.
1990: Michael J Owen; L A James; John Hardy; R Williamson; Alison Goate
Physical mapping around the Alzheimer disease locus on the proximal long arm of chromosome 21.
American journal of human genetics 1990;46(2):316-22.
1990: Alison Goate; John Hardy; Michael J Owen; A Haynes; L James; M Farrall; Michael Mullan; P Roques; Martin N Rossor
Genetics of Alzheimer's disease.
Advances in neurology 1990;51():197-8.
1990: Michael J Owen; Michael Mullan
Molecular genetic studies of manic-depression and schizophrenia.
Trends in neurosciences 1990;13(1):29-31.
1989: John Hardy; Alison Goate; Michael J Owen; Martin N Rossor
Presenile dementia associated with mosaic trisomy 21 in a patient with a Down syndrome child.
Lancet 1989;2(8665):743.
1989: John Hardy; Alison Goate; Michael J Owen; Michael Mullan; Martin N Rossor; R C Pearson
Modelling the occurrence and pathology of Alzheimer's disease.
Neurobiology of aging 1989;10(5):429-31; discussion 446-8.
1989: Michael J Owen; Shon Lewis; R M Murray
Family history and cerebral ventricular enlargement in schizophrenia. A case control study.
The British journal of psychiatry : the journal of mental science 1989;154():629-34.
1989: Alison Goate; A R Haynes; Michael J Owen; M Farrall; L A James; L Y Lai; Michael Mullan; P Roques; Martin N Rossor; R Williamson
Predisposing locus for Alzheimer's disease on chromosome 21.
Lancet 1989;1(8634):352-5.
1989: John Hardy; Michael J Owen; Alison Goate; L A James; A R Haynes; Martin N Rossor; P Roques; Michael Mullan
Molecular genetics of Alzheimer's disease.
Biochemical Society transactions 1989;17(1):75-6.
1988: Michael J Owen; Shon Lewis
Risk factors in schizophrenia.
The British journal of psychiatry : the journal of mental science 1988;153():407.
1988: Michael J Owen; S A Whatley
Polymorphic DNA markers and mental disease.
Psychological medicine 1988;18(3):529-33.
1988: Michael J Owen; Shon Lewis; R M Murray
Obstetric complications and schizophrenia: a computed tomographic study.
Psychological medicine 1988;18(2):331-9.
1987: Michael J Owen; V L Nimgaonkar
The continuum of psychosis and the gene.
The British journal of psychiatry : the journal of mental science 1987;150():566-7.
1986: Michael J Owen; Shon Lewis
Lateral ventricular size in schizophrenia.
Lancet 1986;2(8500):223-4.