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Michael Owen

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Disorders

Physiology

Genes & Molecular Sequences

Procedures

Concepts & Ideas

Geographic Areas

Great Britain

Anatomy

Chromosomes, Human, Pair 22

Chemicals & Drugs

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Publications

TOP 3
Fowler Tom; Langley Kate; Rice Frances; van den Bree Marianne B M; Ross Kenny; Wilkinson Lawrence S; Owen Michael J; O'Donovan Michael C; Thapar Anita
Psychopathy trait scores in adolescents with childhood ADHD: the contribution of genotypes affecting MAOA, 5HTT and COMT activity.
Carroll L S; Kendall K; O'Donovan M C; Owen M J; Williams N M
Evidence that putative ADHD low risk alleles at SNAP25 may increase the risk of schizophrenia.
Hamshere Marian L; Schulze Thomas G; Schumacher Johannes; Corvin Aiden; Owen Michael J; Jamra Rami Abou; Propping Peter; Maier Wolfgang; Orozco y Diaz Guillermo; Mayoral Fermin; Rivas Fabio; Jones Ian; Jones Lisa; Kirov George; Gill Michael; Holmans Peter A; Nöthen Markus M; Cichon Sven; Rietschel Marcella; Craddock Nick
Mood-incongruent psychosis in bipolar disorder: conditional linkage analysis shows genome-wide suggestive linkage at 1q32.3, 7p13 and 20q13.31.

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All Publications

2009: Fowler Tom; Langley Kate; Rice Frances; van den Bree Marianne B M; Ross Kenny; Wilkinson Lawrence S; Owen Michael J; O'Donovan Michael C; Thapar Anita
Psychopathy trait scores in adolescents with childhood ADHD: the contribution of genotypes affecting MAOA, 5HTT and COMT activity.
Psychiatric genetics 2009;19(6):312-9.
2009: Carroll L S; Kendall K; O'Donovan M C; Owen M J; Williams N M
Evidence that putative ADHD low risk alleles at SNAP25 may increase the risk of schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(7):893-9.
2009: Hamshere Marian L; Schulze Thomas G; Schumacher Johannes; Corvin Aiden; Owen Michael J; Jamra Rami Abou; Propping Peter; Maier Wolfgang; Orozco y Diaz Guillermo; Mayoral Fermin; Rivas Fabio; Jones Ian; Jones Lisa; Kirov George; Gill Michael; Holmans Peter A; Nöthen Markus M; Cichon Sven; Rietschel Marcella; Craddock Nick
Mood-incongruent psychosis in bipolar disorder: conditional linkage analysis shows genome-wide suggestive linkage at 1q32.3, 7p13 and 20q13.31.
Bipolar disorders 2009;11(6):610-20.
2009: Kirov George; Rujescu Dan; Ingason Andres; Collier David A; O'Donovan Michael C; Owen Michael J
Neurexin 1 (NRXN1) deletions in schizophrenia.
Schizophrenia bulletin 2009;35(5):851-4.
2009: Sims R; Hollingworth P; Moskvina V; Dowzell K; O'Donovan M C; Powell J; Lovestone S; Brayne C; Rubinsztein D; Owen M J; Williams J; Abraham R
Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease.
Neuroscience letters 2009;461(1):54-9.
2009: Ball H A; Samaan Z; Brewster S; Craddock N; Gill M; Korszun A; Maier W; Middleton L; Mors O; Owen M J; Perry J; Preisig M; Rice J; Rietschel M; Jones L; Jones I; Farmer A E; McGuffin P
Depression, migraine with aura and migraine without aura: their familiality and interrelatedness.
Cephalalgia : an international journal of headache 2009;29(8):848-54.
2009: Kirov G; Zaharieva I; Georgieva L; Moskvina V; Nikolov I; Cichon S; Hillmer A; Toncheva D; Owen M J; O'Donovan M C
A genome-wide association study in 574 schizophrenia trios using DNA pooling.
Molecular psychiatry 2009;14(8):796-803.
2009: Hamshere M L; Green E K; Jones I R; Jones L; Moskvina V; Kirov G; Grozeva D; Nikolov I; Vukcevic D; Caesar S; Gordon-Smith K; Fraser C; Russell E; Breen G; St Clair D; Collier D A; Young A H; Ferrier I N; Farmer A; McGuffin P; Holmans P A; Owen M J; O'Donovan M C; Craddock N
Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept.
The British journal of psychiatry : the journal of mental science 2009;195(1):23-9.
2009: O'Donovan Michael C; Owen Michael J
Genetics and the brain: many pathways to enlightenment.
Human genetics 2009;126(1):1-2.
2009: Holmans Peter; Green Elaine K; Pahwa Jaspreet Singh; Ferreira Manuel A R; Purcell Shaun M; Sklar Pamela; Owen Michael J; O'Donovan Michael C; Craddock Nick
Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder.
American journal of human genetics 2009;85(1):13-24.
2009: O'Donovan Michael C; Craddock Nick J; Owen Michael J
Genetics of psychosis; insights from views across the genome.
Human genetics 2009;126(1):3-12.
2009: Owen Michael J; Williams Hywel J; O'Donovan Michael C
Schizophrenia genetics: advancing on two fronts.
Current opinion in genetics & development 2009;19(3):266-70.
2009: Talkowski Michael E; McClain Lora; Allen Trina; Bradford L Dianne; Calkins Monica; Edwards Neil; Georgieva Lyudmila; Go Rodney; Gur Ruben; Gur Raquel; Kirov George; Chowdari Kodavali; Kwentus Joseph; Lyons Paul; Mansour Hader; McEvoy Joseph; O'Donovan Michael C; O'Jile Judith; Owen Michael J; Santos Alberto; Savage Robert; Toncheva Draga; Vockley Gerard; Wood Joel; Devlin Bernie; Nimgaonkar Vishwajit L
Convergent patterns of association between phenylalanine hydroxylase variants and schizophrenia in four independent samples.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(4):560-9.
2009: Kirov George; Grozeva Detelina; Norton Nadine; Ivanov Dobril; Mantripragada Kiran K; Holmans Peter; Craddock Nick; Owen Michael J; O'Donovan Michael C
Support for the involvement of large copy number variants in the pathogenesis of schizophrenia.
Human molecular genetics 2009;18(8):1497-503.
2009: Moskvina V; Craddock N; Holmans P; Nikolov I; Pahwa J S; Green E; Owen M J; O'Donovan M C
Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk.
Molecular psychiatry 2009;14(3):252-60.
2009: Owen Michael J; Craddock Nick
Diagnosis of functional psychoses: time to face the future.
Lancet 2009;373(9659):190-1.
2009: Fowler Tom; Langley Kate; Rice Frances; Whittinger Naureen; Ross Kenny; van Goozen Stephanie; Owen Michael J; O'Donovan Michael C; van den Bree Marianne B M; Thapar Anita
Psychopathy traits in adolescents with childhood attention-deficit hyperactivity disorder.
The British journal of psychiatry : the journal of mental science 2009;194(1):62-7.
2009: Gerrish A; Williams H; Moskvina V; Owen M J; O'Donovan M C; Williams N M
An examination of MUTED as a schizophrenia susceptibility gene.
Schizophrenia research 2009;107(1):110-1.
2009: Langley Kate; Fowler Tom A; Grady Deborah L; Moyzis Robert K; Holmans Peter A; van den Bree Marianne B M; Owen Michael J; O'Donovan Michael C; Thapar Anita
Molecular genetic contribution to the developmental course of attention-deficit hyperactivity disorder.
European child & adolescent psychiatry 2009;18(1):26-32.
2009: Morgan A R; Hollingworth P; Abraham R; Lovestone S; Brayne C; Rubinsztein D C; Lynch A; Lawlor B; Gill M; O'Donovan M C; Owen M J; Williams J
Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(1):61-4.
2009: Williams Hywel J; Owen Michael J; O'Donovan Michael C
Schizophrenia genetics: new insights from new approaches.
British medical bulletin 2009;91():61-74.
2008: O'Donovan Michael C; Kirov George; Owen Michael J
Phenotypic variations on the theme of CNVs.
Nature genetics 2008;40(12):1392-3.
2008: O'Donovan M C; Craddock N; Owen M J
Schizophrenia: complex genetics, not fairy tales.
Psychological medicine 2008;38(12):1697-9; discussion 1818-20.
2008: Williams Nigel M; Williams Hywel; Majounie Elisa; Norton Nadine; Glaser Beate; Morris Huw R; Owen Michael J; O'Donovan Michael C
Analysis of copy number variation using quantitative interspecies competitive PCR.
Nucleic acids research 2008;36(17):e112.
2008: Hayesmoore J B G; Bray N J; Owen M J; O'Donovan M C
DISC1 mRNA expression is not influenced by common Cis-acting regulatory polymorphisms or imprinting.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(7):1065-9.
2008: Georgieva Lyudmila; Dimitrova Albena; Ivanov Dobril; Nikolov Ivan; Williams Nigel M; Grozeva Detelina; Zaharieva Irina; Toncheva Draga; Owen Michael J; Kirov George; O'Donovan Michael C
Support for neuregulin 1 as a susceptibility gene for bipolar disorder and schizophrenia.
Biological psychiatry 2008;64(5):419-27.
2008: Morgan A R; Hamilton G; Turic D; Jehu L; Harold D; Abraham R; Hollingworth P; Moskvina V; Brayne C; Rubinsztein D C; Lynch A; Lawlor B; Gill M; O'Donovan M; Powell J; Lovestone S; Williams J; Owen M J
Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(6):727-31.
2008: Bray Nicholas J; Holmans Peter A; van den Bree Marianne B; Jones Lesley; Elliston Lyn A; Hughes Gareth; Richards Alexander L; Williams Nigel M; Craddock Nick; Owen Michael J; O'Donovan Michael C
Cis- and trans- loci influence expression of the schizophrenia susceptibility gene DTNBP1.
Human molecular genetics 2008;17(8):1169-74.
2008: Li Yonghong; Grupe Andrew; Rowland Charles; Holmans Peter; Segurado Ricardo; Abraham Richard; Jones Lesley; Catanese Joseph; Ross David; Mayo Kevin; Martinez Maribel; Hollingworth Paul; Goate Alison; Cairns Nigel J; Racette Brad A; Perlmutter Joel S; O'Donovan Michael C; Morris John C; Brayne Carol; Rubinsztein David C; Lovestone Simon; Thal Leon J; Owen Michael J; Williams Julie
Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease.
Human molecular genetics 2008;17(5):759-67.
2008: Talkowski Michael E; Kirov George; Bamne Mikhil; Georgieva Lyudmila; Torres Gonzalo; Mansour Hader; Chowdari Kodavali V; Milanova Vihra; Wood Joel; McClain Lora; Prasad Konasale; Shirts Brian; Zhang Jianping; O'Donovan Michael C; Owen Michael J; Devlin Bernie; Nimgaonkar Vishwajit L
A network of dopaminergic gene variations implicated as risk factors for schizophrenia.
Human molecular genetics 2008;17(5):747-58.
2008: Caspi Avshalom; Langley Kate; Milne Barry; Moffitt Terrie E; O'Donovan Michael; Owen Michael J; Polo Tomas Monica; Poulton Richie; Rutter Michael; Taylor Alan; Williams Benjamin; Thapar Anita
A replicated molecular genetic basis for subtyping antisocial behavior in children with attention-deficit/hyperactivity disorder.
Archives of general psychiatry 2008;65(2):203-10.
2008: Williams Nigel M; Glaser Beate; Norton Nadine; Williams Hywel; Pierce Timothy; Moskvina Valentina; Monks Stephen; Del Favero Jurgen; Goossens Dirk; Rujescu Dan; Giegling Ina; Kirov George; Craddock Nicholas; Murphy Kieran C; O'Donovan Michael C; Owen Michael J
Strong evidence that GNB1L is associated with schizophrenia.
Human molecular genetics 2008;17(4):555-66.
2008: Kirov George; Gumus Dilihan; Chen Wei; Norton Nadine; Georgieva Lyudmila; Sari Murat; O'Donovan Michael C; Erdogan Fikret; Owen Michael J; Ropers Hans-Hilger; Ullmann Reinhard
Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia.
Human molecular genetics 2008;17(3):458-65.
2008: Buxbaum J D; Georgieva L; Young J J; Plescia C; Kajiwara Y; Jiang Y; Moskvina V; Norton N; Peirce T; Williams H; Craddock N J; Carroll L; Corfas G; Davis K L; Owen M J; Harroch S; Sakurai T; O'Donovan M C
Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene.
Molecular psychiatry 2008;13(2):162-72.
2008: Langley K; Turic D; Rice F; Holmans P; van den Bree M B M; Craddock N; Kent L; Owen M J; O'Donovan M C; Thapar A
Testing for gene x environment interaction effects in attention deficit hyperactivity disorder and associated antisocial behavior.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(1):49-53.
2008: van Amelsvoort T; Zinkstok J; Figee M; Daly E; Morris R; Owen M J; Murphy K C; De Haan L; Linszen D H; Glaser B; Murphy D G M
Effects of a functional COMT polymorphism on brain anatomy and cognitive function in adults with velo-cardio-facial syndrome.
Psychological medicine 2008;38(1):89-100.
2008: Richards Alexander L; Holmans Peter; O'Donovan Michael C; Owen Michael J; Jones Lesley
A comparison of four clustering methods for brain expression microarray data.
BMC bioinformatics 2008;9():490.
2008: Abraham Richard; Moskvina Valentina; Sims Rebecca; Hollingworth Paul; Morgan Angharad; Georgieva Lyudmila; Dowzell Kimberley; Cichon Sven; Hillmer Axel M; O'Donovan Michael C; Williams Julie; Owen Michael J; Kirov George
A genome-wide association study for late-onset Alzheimer's disease using DNA pooling.
BMC medical genomics 2008;1():44.
2008: Zaharieva Irina; Georgieva Lyudmila; Nikolov Ivan; Kirov George; Owen Michael J; O'Donovan Michael C; Toncheva Draga
Association study in the 5q31-32 linkage region for schizophrenia using pooled DNA genotyping.
BMC psychiatry 2008;8():11.
2007: Williams H J; Norton N; Peirce T; Dwyer S; Williams N M; Moskvina V; Owen M J; O'Donovan M C
Association analysis of the glial cell line-derived neurotrophic factor (GDNF) gene in schizophrenia.
Schizophrenia research 2007;97(1-3):271-6.
2007: Thapar Anita; Langley Kate; Owen Michael J; O'Donovan Michael C
Advances in genetic findings on attention deficit hyperactivity disorder.
Psychological medicine 2007;37(12):1681-92.
2007: Zammit Stanley; Spurlock Gillian; Williams Hywel; Norton Nadine; Williams Nigel; O'Donovan Michael C; Owen Michael J
Genotype effects of CHRNA7, CNR1 and COMT in schizophrenia: interactions with tobacco and cannabis use.
The British journal of psychiatry : the journal of mental science 2007;191():402-7.
2007: Hamshere Marian L; Holmans Peter A; Avramopoulos Dimitrios; Bassett Susan S; Blacker Deborah; Bertram Lars; Wiener Howard; Rochberg Nan; Tanzi Rudolph E; Myers Amanda; Wavrant-De Vrièze Fabienne; Go Rodney; Fallin Daniele; Lovestone Simon; Hardy John; Goate Alison; O'Donovan Michael; Williams Julie; Owen Michael J
Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease.
Human molecular genetics 2007;16(22):2703-12.
2007: Morgan A R; Turic D; Jehu L; Hamilton G; Hollingworth P; Moskvina V; Jones L; Lovestone S; Brayne C; Rubinsztein D C; Lawlor B; Gill M; O'Donovan M C; Owen M J; Williams J
Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(6):762-70.
2007: Rice Frances; Lewis Allyson; Harold Gordon; van den Bree Marianne; Boivin Jacky; Hay Dale F; Owen Michael J; Thapar Anita
Agreement between maternal report and antenatal records for a range of pre and peri-natal factors: the influence of maternal and child characteristics.
Early human development 2007;83(8):497-504.
2007: Owen Michael J; Craddock Nick; Jablensky Assen
The genetic deconstruction of psychosis.
Schizophrenia bulletin 2007;33(4):905-11.
2007: Norton Nadine; Williams Hywel J; Dwyer Sarah; Carroll Liam; Peirce Tim; Moskvina Valentina; Segurado Ricardo; Nikolov Ivan; Williams Nigel M; Ikeda Masashi; Iwata Nakao; Owen Michael J; O'Donovan Michael C
Association analysis of AKT1 and schizophrenia in a UK case control sample.
Schizophrenia research 2007;93(1-3):58-65.
2007: Craddock Nick; Owen Michael J
Rethinking psychosis: the disadvantages of a dichotomous classification now outweigh the advantages.
World psychiatry : official journal of the World Psychiatric Association (WPA) 2007;6(2):84-91.
2007: Hamilton Gillian; Proitsi Petra; Jehu Luke; Morgan Angharad; Williams Julie; O'Donovan Michael C; Owen Michael J; Powell John F; Lovestone Simon
Candidate gene association study of insulin signaling genes and Alzheimer's disease: evidence for SOS2, PCK1, and PPARgamma as susceptibility loci.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(4):508-16.
2007: Harold D; Jehu L; Turic D; Hollingworth P; Moore P; Summerhayes P; Moskvina V; Foy C; Archer N; Hamilton B A; Lovestone S; Powell J; Brayne C; Rubinsztein D C; Jones L; O'Donovan M C; Owen M J; Williams J
Interaction between the ADAM12 and SH3MD1 genes may confer susceptibility to late-onset Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(4):448-52.
2007: Williams Hywel J; Owen Michael J; O'Donovan Michael C
Is COMT a susceptibility gene for schizophrenia?
Schizophrenia bulletin 2007;33(3):635-41.
2007: Grupe Andrew; Abraham Richard; Li Yonghong; Rowland Charles; Hollingworth Paul; Morgan Angharad; Jehu Luke; Segurado Ricardo; Stone David; Schadt Eric; Karnoub Maha; Nowotny Petra; Tacey Kristina; Catanese Joseph; Sninsky John; Brayne Carol; Rubinsztein David; Gill Michael; Lawlor Brian; Lovestone Simon; Holmans Peter; O'Donovan Michael; Morris John C; Thal Leon; Goate Alison; Owen Michael J; Williams Julie
Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants.
Human molecular genetics 2007;16(8):865-73.
2007: Craddock Nick; O'Donovan Michael C; Owen Michael J
Phenotypic and genetic complexity of psychosis. Invited commentary on ... Schizophrenia: a common disease caused by multiple rare alleles.
The British journal of psychiatry : the journal of mental science 2007;190():200-3.
2007: Gunnell D; Lewis S; Wilkinson J; Georgieva L; Davey G Smith; Day I N M; Holly J M P; O'Donovan M C; Owen M J; Kirov G; Zammit S
IGF1, growth pathway polymorphisms and schizophrenia: a pooling study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(1):117-20.
2006: Harold D; Paracchini S; Scerri T; Dennis M; Cope N; Hill G; Moskvina V; Walter J; Richardson A J; Owen M J; Stein J F; Green E D; O'Donovan M C; Williams J; Monaco A P
Further evidence that the KIAA0319 gene confers susceptibility to developmental dyslexia.
Molecular psychiatry 2006;11(12):1085-91, 1061.
2006: Glaser Beate; Moskvina Valentina; Kirov George; Murphy Kieran C; Williams Hywel; Williams Nigel; Owen Michael J; O'Donovan Michael C
Analysis of ProDH, COMT and ZDHHC8 risk variants does not support individual or interactive effects on schizophrenia susceptibility.
Schizophrenia research 2006;87(1-3):21-7.
2006: Zammit Stanley; Lewis Glyn; Thapar Anita; Owen Richard; Jones Gaynor; Jones Susan; Sanders Rob; Milham Charis; Mahdi Ameera; O'Donovan Michael C; Owen Michael J
Phenotypic variation between parent-offspring trios and non-trios in genetic studies of schizophrenia.
Journal of psychiatric research 2006;40(7):622-6.
2006: Hollingworth Paul; Hamshere Marian L; Moskvina Valentina; Dowzell Kimberley; Moore Pamela J; Foy Catherine; Archer Nicola; Lynch Aoibhinn; Lovestone Simon; Brayne Carol; Rubinsztein David C; Lawlor Brian; Gill Mike; Owen Michael J; Williams Julie
Four components describe behavioral symptoms in 1,120 individuals with late-onset Alzheimer's disease.
Journal of the American Geriatrics Society 2006;54(9):1348-54.
2006: Green E K; Norton N; Peirce T; Grozeva D; Kirov G; Owen M J; O'Donovan M C; Craddock N
Evidence that a DISC1 frame-shift deletion associated with psychosis in a single family may not be a pathogenic mutation.
Molecular psychiatry 2006;11(9):798-9.
2006: Georgieva Lyudmila; Moskvina Valentina; Peirce Tim; Norton Nadine; Bray Nicholas J; Jones Lesley; Holmans Peter; Macgregor Stuart; Zammit Stanley; Wilkinson Jennifer; Williams Hywel; Nikolov Ivan; Williams Nigel; Ivanov Dobril; Davis Kenneth L; Haroutunian Vahram; Buxbaum Joseph D; Craddock Nick; Kirov George; Owen Michael J; O'Donovan Michael C
Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(33):12469-74.
2006: Rees Mark I; Harvey Kirsten; Pearce Brian R; Chung Seo-Kyung; Duguid Ian C; Thomas Philip; Beatty Sarah; Graham Gail E; Armstrong Linlea; Shiang Rita; Abbott Kim J; Zuberi Sameer M; Stephenson John B P; Owen Michael J; Tijssen Marina A J; van den Maagdenberg Arn M J M; Smart Trevor G; Supplisson Stéphane; Harvey Robert J
Mutations in the gene encoding GlyT2 (SLC6A5) define a presynaptic component of human startle disease.
Nature genetics 2006;38(7):801-6.
2006: Hamshere M L; Williams N M; Norton N; Williams H; Cardno A G; Zammit S; Jones L A; Murphy K C; Sanders R D; McCarthy G; Gray M Y; Jones G; Holmans P; O'Donovan M C; Owen M J; Craddock N
Genome wide significant linkage in schizophrenia conditioning on occurrence of depressive episodes.
Journal of medical genetics 2006;43(7):563-7.
2006: Hamilton Gillian; Samedi Farzana; Knight Jo; Archer Nicola; Foy Catherine; Walter Sarah; Turic Dragana; Jehu Luke; Moore Pamela; Hollingworth Paul; O'Donovan Michael C; Williams Julie; Owen Michael J; Lovestone Simon; Powell John F
Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease.
Neuroscience letters 2006;401(1-2):77-80.
2006: Craddock N; Owen M J; O'Donovan M C
The catechol-O-methyl transferase (COMT) gene as a candidate for psychiatric phenotypes: evidence and lessons.
Molecular psychiatry 2006;11(5):446-58.
2006: Williams Nigel M; Green Elaine K; Macgregor Stuart; Dwyer Sarah; Norton Nadine; Williams Hywel; Raybould Rachel; Grozeva Detelina; Hamshere Marian; Zammit Stanley; Jones Lisa; Cardno Alastair; Kirov George; Jones Ian; O'Donovan Michael C; Owen Michael J; Craddock Nick
Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder.
Archives of general psychiatry 2006;63(4):366-73.
2006: Norton Nadine; Williams Hywel J; Owen Michael J
An update on the genetics of schizophrenia.
Current opinion in psychiatry 2006;19(2):158-64.
2006: Harold Denise; Macgregor Stuart; Patterson Cathryn E; Hollingworth Paul; Moore Pamela; Owen Michael J; Williams Julie; O'Donovan Michael; Passmore Peter; McIlroy Stephen; Jones Lesley
A single nucleotide polymorphism in CHAT influences response to acetylcholinesterase inhibitors in Alzheimer's disease.
Pharmacogenetics and genomics 2006;16(2):75-7.
2006: Peirce Timothy R; Bray Nicholas J; Williams Nigel M; Norton Nadine; Moskvina Valentina; Preece Anna; Haroutunian Vahram; Buxbaum Joseph D; Owen Michael J; O'Donovan Michael C
Convergent evidence for 2',3'-cyclic nucleotide 3'-phosphodiesterase as a possible susceptibility gene for schizophrenia.
Archives of general psychiatry 2006;63(1):18-24.
2006: Green Elaine K; Raybould Rachel; Macgregor Stuart; Hyde Sally; Young Allan H; O'Donovan Michael C; Owen Michael J; Kirov George; Jones Lisa; Jones Ian; Craddock Nick
Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK.
The British journal of psychiatry : the journal of mental science 2006;188():21-5.
2006: Craddock Nick; O'Donovan Michael C; Owen Michael J
Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology.
Schizophrenia bulletin 2006;32(1):9-16.
2006: Smemo Scott; Nowotny Petra; Hinrichs Anthony L; Kauwe John S K; Cherny Sara; Erickson Katherine; Myers Amanda J; Kaleem Mona; Marlowe Lauren; Gibson Alison M; Hollingworth Paul; O'Donovan Michael C; Morris Chris M; Holmans Peter; Lovestone Simon; Morris John C; Thal Leon; Li Yonghong; Grupe Andrew; Hardy John; Owen Michael J; Williams Julie; Goate Alison
Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease.
Annals of neurology 2006;59(1):21-6.
2006: Norton Nadine; Moskvina Valentina; Morris Derek W; Bray Nicholas J; Zammit Stanley; Williams Nigel M; Williams Hywel J; Preece Anna C; Dwyer Sarah; Wilkinson Jennifer C; Spurlock Gillian; Kirov George; Buckland Paul; Waddington John L; Gill Michael; Corvin Aiden P; Owen Michael J; O'Donovan Michael C
Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2006;141B(1):96-101.
2006: Williams Nigel M; O'Donovan Michael C; Owen Michael J
Chromosome 22 deletion syndrome and schizophrenia.
International review of neurobiology 2006;73():1-27.
2006: Moskvina Valentina; Craddock Nick; Holmans Peter; Owen Michael J; O'Donovan Michael C
Effects of differential genotyping error rate on the type I error probability of case-control studies.
Human heredity 2006;61(1):55-64.
2006: Kirov George; Nikolov Ivan; Georgieva Lyudmila; Moskvina Valentina; Owen Michael J; O'Donovan Michael C
Pooled DNA genotyping on Affymetrix SNP genotyping arrays.
BMC genomics 2006;7():27.
2005: McGuffin Peter; Knight Jo; Breen Gerome; Brewster Shyama; Boyd Peter R; Craddock Nick; Gill Mike; Korszun Ania; Maier Wolfgang; Middleton Lefkos; Mors Ole; Owen Michael J; Perry Julia; Preisig Martin; Reich Theodore; Rice John; Rietschel Marcella; Jones Lisa; Sham Pak; Farmer Anne E
Whole genome linkage scan of recurrent depressive disorder from the depression network study.
Human molecular genetics 2005;14(22):3337-45.
2005: Langley K; Turic D; Peirce T R; Mills S; Van Den Bree M B; Owen M J; O'Donovan M C; Thapar A
No support for association between the dopamine transporter (DAT1) gene and ADHD.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;139B(1):7-10.
2005: Thapar Anita; O'Donovan Michael; Owen Michael J
The genetics of attention deficit hyperactivity disorder.
Human molecular genetics 2005;14 Spec No. 2():R275-82.
2005: Hamshere Marian L; Bennett Phil; Williams Nigel; Segurado Ricardo; Cardno Alastair; Norton Nadine; Lambert David; Williams Hywel; Kirov George; Corvin Aiden; Holmans Peter; Jones Lisa; Jones Ian; Gill Michael; O'Donovan Michael C; Owen Michael J; Craddock Nick
Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13.
Archives of general psychiatry 2005;62(10):1081-8.
2005: Williams Nigel M; O'Donovan Michael C; Owen Michael J
Is the dysbindin gene (DTNBP1) a susceptibility gene for schizophrenia?
Schizophrenia bulletin 2005;31(4):800-5.
2005: Glaser B; Kirov G; Bray N J; Green E; O'Donovan M C; Craddock N; Owen M J
Identification of a potential bipolar risk haplotype in the gene encoding the winged-helix transcription factor RFX4.
Molecular psychiatry 2005;10(10):920-7.
2005: Kent L; Green E; Hawi Z; Kirley A; Dudbridge F; Lowe N; Raybould R; Langley K; Bray N; Fitzgerald M; Owen M J; O'Donovan M C; Gill M; Thapar A; Craddock N
Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD.
Molecular psychiatry 2005;10(10):939-43.
2005: Williams Hywel J; Glaser Beate; Williams Nigel M; Norton Nadine; Zammit Stanley; MacGregor Stuart; Kirov George K; Owen Michael J; O'Donovan Michael C
No association between schizophrenia and polymorphisms in COMT in two large samples.
The American journal of psychiatry 2005;162(9):1736-8.
2005: Owen M J; Craddock N; O'Donovan M C
Schizophrenia: genes at last?
Trends in genetics : TIG 2005;21(9):518-25.
2005: Lambert D; Middle F; Hamshere M L; Segurado R; Raybould R; Corvin A; Green E; O'Mahony E; Nikolov I; Mulcahy T; Haque S; Bort S; Bennett P; Norton N; Owen M J; Kirov G; Lendon C; Jones L; Jones I; Holmans P; Gill M; Craddock N
Stage 2 of the Wellcome Trust UK-Irish bipolar affective disorder sibling-pair genome screen: evidence for linkage on chromosomes 6q16-q21, 4q12-q21, 9p21, 10p14-p12 and 18q22.
Molecular psychiatry 2005;10(9):831-41.
2005: Kirov George; Tredget John; John Rhys; Owen Michael J; Lazarus John H
A cross-sectional and a prospective study of thyroid disorders in lithium-treated patients.
Journal of affective disorders 2005;87(2-3):313-7.
2005: Glaser Beate; Schumacher Johannes; Williams Hywel J; Jamra Rami Abou; Ianakiev Nikolai; Milev Radoi; Ohlraun Stephanie; Schulze Thomas G; Czerski Piotr M; Hauser Joanna; Jönsson Erick G; Sedvall Göran C; Klopp Norman; Illig Thomas; Becker Tim; Propping Peter; Williams Nigel M; Cichon Sven; Kirov George; Rietschel Marcella; Murphy Kieran C; O'Donovan Michael C; Nöthen Markus M; Owen Michael J
No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples.
Biological psychiatry 2005;58(1):78-80.
2005: Bray Nicholas J; Preece Anna; Williams Nigel M; Moskvina Valentina; Buckland Paul R; Owen Michael J; O'Donovan Michael C
Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression.
Human molecular genetics 2005;14(14):1947-54.
2005: Nowotny Petra; Hinrichs Anthony L; Smemo Scott; Kauwe John S K; Maxwell Taylor; Holmans Peter; Hamshere Marian; Turic Dragana; Jehu Luke; Hollingworth Paul; Moore Pamela; Bryden Leslie; Myers Amanda; Doil Lisa M; Tacey Kristina M; Gibson Alison M; McKeith Ian G; Perry Robert H; Morris Chris M; Thal Leon; Morris John C; O'Donovan Michael C; Lovestone Simon; Grupe Andrew; Hardy John; Owen Michael J; Williams Julie; Goate Alison
Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;136B(1):62-8.
2005: Turic Darko; Langley Kate; Williams Hywel; Norton Nadine; Williams Nigel M; Moskvina Valentina; Van den Bree Marianne B; Owen Michael J; Thapar Anita; O'Donovan Michael C
A family based study implicates solute carrier family 1-member 3 (SLC1A3) gene in attention-deficit/hyperactivity disorder.
Biological psychiatry 2005;57(11):1461-6.
2005: Green Elaine K; Raybould Rachel; Macgregor Stuart; Gordon-Smith Katherine; Heron Jess; Hyde Sally; Grozeva Detelina; Hamshere Marian; Williams Nigel; Owen Michael J; O'Donovan Michael C; Jones Lisa; Jones Ian; Kirov George; Craddock Nick
Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder.
Archives of general psychiatry 2005;62(6):642-8.
2005: Kirov George; O'Donovan Michael C; Owen Michael J
Finding schizophrenia genes.
The Journal of clinical investigation 2005;115(6):1440-8.
2005: Raybould Rachel; Green Elaine K; MacGregor Stuart; Gordon-Smith Katherine; Heron Jess; Hyde Sally; Caesar Sian; Nikolov Ivan; Williams Nigel; Jones Lisa; O'Donovan Michael C; Owen Michael J; Jones Ian; Kirov George; Craddock Nick
Bipolar disorder and polymorphisms in the dysbindin gene (DTNBP1).
Biological psychiatry 2005;57(7):696-701.
2005: Cope Natalie; Harold Denise; Hill Gary; Moskvina Valentina; Stevenson Jim; Holmans Peter; Owen Michael J; O'Donovan Michael C; Williams Julie
Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia.
American journal of human genetics 2005;76(4):581-91.
2005: Craddock N; O'Donovan M C; Owen M J
The genetics of schizophrenia and bipolar disorder: dissecting psychosis.
Journal of medical genetics 2005;42(3):193-204.
2005: Cope N A; Hill G; van den Bree M; Harold D; Moskvina V; Green E K; Owen M J; Williams J; O'Donovan M C
No support for association between dyslexia susceptibility 1 candidate 1 and developmental dyslexia.
Molecular psychiatry 2005;10(3):237-8.
2005: Green Elaine; Elvidge Gareth; Jacobsen Nick; Glaser Beate; Jones Ian; O'Donovan Michael C; Kirov George; Owen Michael J; Craddock Nick
Localization of bipolar susceptibility locus by molecular genetic analysis of the chromosome 12q23-q24 region in two pedigrees with bipolar disorder and Darier's disease.
The American journal of psychiatry 2005;162(1):35-42.
2005: Glaser Beate; Kirov George; Green Elaine; Craddock Nick; Owen Michael J
Linkage disequilibrium mapping of bipolar affective disorder at 12q23-q24 provides evidence for association at CUX2 and FLJ32356.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;132B(1):38-45.
2005: Owen Michael J
Genomic approaches to schizophrenia.
Clinical therapeutics 2005;27 Suppl A():S2-7.
2005: Norton Nadine; Owen Michael J
HTR2A: association and expression studies in neuropsychiatric genetics.
Annals of medicine 2005;37(2):121-9.
2005: Norton Nadine; Williams Hywel J; Dwyer Sarah; Ivanov Dobril; Preece Anna C; Gerrish Amy; Williams Nigel M; Yerassimou Pamela; Zammit Stanley; O'Donovan Michael C; Owen Michael J
No evidence for association between polymorphisms in GRM3 and schizophrenia.
BMC psychiatry 2005;5():23.
2005: Dimitrova A; Milanova V; Krastev S; Nikolov I; Toncheva D; Owen M J; Kirov G
Association study of myo-inositol monophosphatase 2 (IMPA2) polymorphisms with bipolar affective disorder and response to lithium treatment.
The pharmacogenomics journal 2005;5(1):35-41.
2004: Bray Nicholas J; Jehu Luke; Moskvina Valentina; Buxbaum Joseph D; Dracheva Stella; Haroutunian Vahram; Williams Julie; Buckland Paul R; Owen Michael J; O'Donovan Michael C
Allelic expression of APOE in human brain: effects of epsilon status and promoter haplotypes.
Human molecular genetics 2004;13(22):2885-92.
2004: Farbrother Jane E; Kirov George; Owen Michael J; Pong-Wong Ricardo; Haley Chris S; Guggenheim Jeremy A
Linkage analysis of the genetic loci for high myopia on 18p, 12q, and 17q in 51 U.K. families.
Investigative ophthalmology & visual science 2004;45(9):2879-85.
2004: Farbrother Jane E; Kirov George; Owen Michael J; Guggenheim Jeremy A
Family aggregation of high myopia: estimation of the sibling recurrence risk ratio.
Investigative ophthalmology & visual science 2004;45(9):2873-8.
2004: Morris D W; Ivanov D; Robinson L; Williams N; Stevenson J; Owen M J; Williams J; O'Donovan M C
Association analysis of two candidate phospholipase genes that map to the chromosome 15q15.1-15.3 region associated with reading disability.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;129B(1):97-103.
2004: Zammit Stanley; Jones Gaynor; Jones Susan J; Norton Nadine; Sanders Robert D; Milham Charis; McCarthy Geraldine M; Jones Lisa A; Cardno Alastair G; Gray Marion; Murphy Kieran C; O'Donovan Michael C; Owen Michael J
Polymorphisms in the MAOA, MAOB, and COMT genes and aggressive behavior in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;128B(1):19-20.
2004: Harvey Kirsten; Duguid Ian C; Alldred Melissa J; Beatty Sarah E; Ward Hamish; Keep Nicholas H; Lingenfelter Sue E; Pearce Brian R; Lundgren Johan; Owen Michael J; Smart Trevor G; Lüscher Bernhard; Rees Mark I; Harvey Robert J
The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(25):5816-26.
2004: Reid Suzanne J; van Roon-Mom Willeke M C; Wood Phil C; Rees Mark I; Owen Michael J; Faull Richard L M; Dragunow Mike; Snell Russell G
TBP, a polyglutamine tract containing protein, accumulates in Alzheimer's disease.
Brain research. Molecular brain research 2004;125(1-2):120-8.
2004: Williams Nigel M; Owen Michael J
Genetic abnormalities of chromosome 22 and the development of psychosis.
Current psychiatry reports 2004;6(3):176-82.
2004: Owen Michael J; Williams Nigel M; O'Donovan Michael C
Dysbindin-1 and schizophrenia: from genetics to neuropathology.
The Journal of clinical investigation 2004;113(9):1255-7.
2004: Korszun Ania; Moskvina Valentina; Brewster Shyama; Craddock Nick; Ferrero François; Gill Michael; Jones Ian Richard; Jones Lisa Anne; Maier Wolfgang; Mors Ole; Owen Michael J; Preisig Martin; Reich Theodore; Rietschel Marcella; Farmer Anne; McGuffin Peter
Familiality of symptom dimensions in depression.
Archives of general psychiatry 2004;61(5):468-74.
2004: Kirov George; Ivanov Dobril; Williams Nigel M; Preece Anna; Nikolov Ivan; Milev Radoi; Koleva Svetlinka; Dimitrova Albena; Toncheva Draga; O'Donovan Michael C; Owen Michael J
Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from Bulgaria.
Biological psychiatry 2004;55(10):971-5.
2004: Turic D; Langley K; Kirov G; Owen M J; Thapar A; O'Donovan M C
Direct analysis of the genes encoding G proteins G alpha T2, G alpha o, G alpha Z in ADHD.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;127B(1):68-72.
2004: Fekadu Abebaw; Shibre Teshome; Alem Atalay; Kebede Derge; Kebreab Samuel; Negash Alemayehu; Owen Michael J
Bipolar disorder among an isolated island community in Ethiopia.
Journal of affective disorders 2004;80(1):1-10.
2004: Williams N M; Preece A; Morris D W; Spurlock G; Bray N J; Stephens M; Norton N; Williams H; Clement M; Dwyer S; Curran C; Wilkinson J; Moskvina V; Waddington J L; Gill M; Corvin A P; Zammit S; Kirov G; Owen M J; O'Donovan M C
Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1).
Archives of general psychiatry 2004;61(4):336-44.
2004: Cook Lynnette J; Ho Luk W; Taylor Alison E; Brayne Carol; Evans John Grimley; Xuereb John; Cairns Nigel J; Pritchard Antonia; Lemmon Helen; Mann David; St Clair David; Turic Dragana; Hollingworth Paul; Moore Pamela J; Jehu Luke; Archer Nicola; Walter Sarah; Foy Catherine; Edmondson Amanda; Powell John; Lovestone Simon; Owen Michael J; Williams Julie; Lendon Corinne; Rubinsztein David C
Candidate gene association studies of the alpha 4 (CHRNA4) and beta 2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease.
Neuroscience letters 2004;358(2):142-6.
2004: Williams Nigel M; Preece Anna; Spurlock Gillian; Norton Nadine; Williams Hywel J; McCreadie Robin G; Buckland Paul; Sharkey Val; Chowdari Kodavali V; Zammit Stanley; Nimgaonkar Vishwajit; Kirov George; Owen Michael J; O'Donovan Michael C
Support for RGS4 as a susceptibility gene for schizophrenia.
Biological psychiatry 2004;55(2):192-5.
2004: Bray N J; Buckland P R; Hall H; Owen M J; O'Donovan M C
The serotonin-2A receptor gene locus does not contain common polymorphism affecting mRNA levels in adult brain.
Molecular psychiatry 2004;9(1):109-14.
2004: Myers Amanda J; Marshall Helen; Holmans Peter; Compton Danielle; Crook Richard J P; Mander Adrian P; Nowotny Petra; Smemo Scott; Dunstan Melanie; Jehu Luke; Wang Jen C; Hamshere Marian; Morris John C; Norton Joanne; Chakraventy Sumi; Tunstall Nigel; Lovestone Simon; Petersen Ronald; O'Donovan Michael; Jones Lesley; Williams Julie; Owen Michael J; Hardy John; Goate Alison
Variation in the urokinase-plasminogen activator gene does not explain the chromosome 10 linkage signal for late onset AD.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;124B(1):29-37.
2004: Owen M J; Williams N M; O'Donovan M C
The molecular genetics of schizophrenia: new findings promise new insights.
Molecular psychiatry 2004;9(1):14-27.
2004: Mills Sophie; Langley Kate; Van den Bree Marianne; Street Eddy; Turic Darko; Owen Michael J; O'Donovan Michael C; Thapar Anita
No evidence of association between Catechol-O-Methyltransferase (COMT) Val158Met genotype and performance on neuropsychological tasks in children with ADHD: a case-control study.
BMC psychiatry 2004;4():15.
2004: Norton Nadine; Williams Nigel M; O'Donovan Michael C; Owen Michael J
DNA pooling as a tool for large-scale association studies in complex traits.
Annals of medicine 2004;36(2):146-52.
2003: Heron J; Jones I; Williams J; Owen M J; Craddock N; Jones L A
Self-reported schizotypy and bipolar disorder: demonstration of a lack of specificity of the Kings Schizotypy Questionnaire.
Schizophrenia research 2003;65(2-3):153-8.
2003: Williams N M; Norton N; Williams H; Ekholm B; Hamshere M L; Lindblom Y; Chowdari K V; Cardno A G; Zammit S; Jones L A; Murphy K C; Sanders R D; McCarthy G; Gray M Y; Jones G; Holmans P; Nimgaonkar V; Adolfson R; Osby U; Terenius L; Sedvall G; O'Donovan M C; Owen M J
A systematic genomewide linkage study in 353 sib pairs with schizophrenia.
American journal of human genetics 2003;73(6):1355-67.
2003: Ivanov D; Kirov G; Norton N; Williams H J; Williams N M; Nikolov I; Tzwetkova R; Stambolova S M; Murphy K C; Toncheva D; Thapar A; O'Donovan M C; Owen M J
Chromosome 22q11 deletions, velo-cardio-facial syndrome and early-onset psychosis. Molecular genetic study.
The British journal of psychiatry : the journal of mental science 2003;183():409-13.
2003: Zammit Stanley; Allebeck Peter; Dalman Christina; Lundberg Ingvar; Hemmingson Tomas; Owen Michael J; Lewis Glyn
Paternal age and risk for schizophrenia.
The British journal of psychiatry : the journal of mental science 2003;183():405-8.
2003: Kirov George; Georgieva Lyudmila; Williams Nigel; Nikolov Ivan; Norton Nadine; Toncheva Draga; O'Donovan Michael; Owen Michael J
Variation in the protocadherin gamma A gene cluster.
Genomics 2003;82(4):433-40.
2003: O'Donovan Michael C; Williams Nigel M; Owen Michael J
Recent advances in the genetics of schizophrenia.
Human molecular genetics 2003;12 Spec No 2():R125-33.
2003: Payton Antony; Turic Darko; Langley Kate; Mills Sophie; Lawson Deborah C; Van den Bree Marianne; Owen Michael J; O'Donovan Michael C; Ollier William; Worthington Jane; Thapar Anita
No evidence of association between HLA-DRB1 and attention deficit hyperactivity disorder.
Psychiatric genetics 2003;13(3):183-5.
2003: Harold Denise; Peirce Timothy; Moskvina Valentina; Myers Amanda; Jones Susan; Hollingworth Paul; Moore Pamela; Lovestone Simon; Powell John; Foy Catherine; Archer Nicola; Walter Sarah; Edmonson Amanda; McIlroy Stephen; Craig David; Passmore Peter A; Goate Alison; Hardy John; O'Donovan Michael; Williams Julie; Liddell Malcolm; Owen Michael J; Jones Lesley
Sequence variation in the CHAT locus shows no association with late-onset Alzheimer's disease.
Human genetics 2003;113(3):258-67.
2003: Williams H J; Williams N; Spurlock G; Norton N; Ivanov D; McCreadie R G; Preece A; Sharkey V; Jones S; Zammit S; Nikolov I; Kehaiov I; Thapar A; Murphy K C; Kirov G; Owen M J; O'Donovan M C
Association between PRODH and schizophrenia is not confirmed.
Molecular psychiatry 2003;8(7):644-5.
2003: Williams H J; Williams N; Spurlock G; Norton N; Zammit S; Kirov G; Owen M J; O'Donovan M C
Detailed analysis of PRODH and PsPRODH reveals no association with schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;120B(1):42-6.
2003: Norton N; Williams H J; Williams N M; Spurlock G; Zammit S; Jones G; Jones S; Owen R; O'Donovan M C; Owen M J
Mutation screening of the Homer gene family and association analysis in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;120B(1):18-21.
2003: Bray Nicholas J; Buckland Paul R; Williams Nigel M; Williams Hywel J; Norton Nadine; Owen Michael J; O'Donovan Michael C
A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain.
American journal of human genetics 2003;73(1):152-61.
2003: Bray Nicholas J; Buckland Paul R; Owen Michael J; O'Donovan Michael C
Cis-acting variation in the expression of a high proportion of genes in human brain.
Human genetics 2003;113(2):149-53.
2003: Rees Mark I; Harvey Kirsten; Ward Hamish; White Julia H; Evans Luc; Duguid Ian C; Hsu Cynthia C-H; Coleman Sharon L; Miller Jan; Baer Kristin; Waldvogel Henry J; Gibbon Francis; Smart Trevor G; Owen Michael J; Harvey Robert J; Snell Russell G
Isoform heterogeneity of the human gephyrin gene (GPHN), binding domains to the glycine receptor, and mutation analysis in hyperekplexia.
The Journal of biological chemistry 2003;278(27):24688-96.
2003: Langley Kate; Payton Antony; Hamshere Marian L; Pay Helen M; Lawson Deborah C; Turic Darko; Ollier William; Worthington Jane; Owen Michael J; O'Donovan Michael C; Thapar Anita
No evidence of association of two 5HT transporter gene polymorphisms and attention deficit hyperactivity disorder.
Psychiatric genetics 2003;13(2):107-10.
2003: Georgieva Lyudmila; Nikolov Ivan; Poriazova Nadezhda; Jones Gaynor; Toncheva Draga; Kirov George; Owen Michael J
Genetic variation in the seven-pass transmembrane cadherin CELSR1: lack of association with schizophrenia.
Psychiatric genetics 2003;13(2):103-6.
2003: Green Elaine K; Elvidge Gareth P; Owen Michael J; Craddock Nick
Mutational analysis of two positional candidate susceptibility genes for bipolar disorder on chromosome 12q23-q24: phenylalanine hydroxylase and human LIM-homeobox LHX5.
Psychiatric genetics 2003;13(2):97-101.
2003: Reid Suzanne J; Rees Mark I; van Roon-Mom Willeke M C; Jones A Lesley; MacDonald Marcy E; Sutherland Greg; During Matthew J; Faull Richard L M; Owen Michael J; Dragunow Mike; Snell Russell G
Molecular investigation of TBP allele length: a SCA17 cellular model and population study.
Neurobiology of disease 2003;13(1):37-45.
2003: Williams N M; Preece A; Spurlock G; Norton N; Williams H J; Zammit S; O'Donovan M C; Owen M J
Support for genetic variation in neuregulin 1 and susceptibility to schizophrenia.
Molecular psychiatry 2003;8(5):485-7.
2003: Kirov George; Georgieva Ludmila; Nikolov Ivan; Zammit Stan; Jones Gaynor; Poriazova Nadezhda; Tolev Todor; Owen Richard; Jones Sue; Owen Michael J
Association analysis of the HOPA12bp polymorphism in schizophrenia and manic depressive illness.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;118B(1):16-9.
2003: Turic D; Robinson L; Duke M; Morris D W; Webb V; Hamshere M; Milham C; Hopkin E; Pound K; Fernando S; Grierson A; Easton M; Williams N; Van Den Bree M; Chowdhury R; Gruen J; Stevenson J; Krawczak M; Owen M J; O'Donovan M C; Williams J
Linkage disequilibrium mapping provides further evidence of a gene for reading disability on chromosome 6p21.3-22.
Molecular psychiatry 2003;8(2):176-85.
2003: Rice Frances; Abraham Richard; Rudrasingham Varuni; Owen Michael J; Williams Julie
Memory for new information as a cognitive marker of liability to Alzheimer's disease in a high risk group: a research note.
International journal of geriatric psychiatry 2003;18(2):155-60.
2003: Lawson Deborah C; Turic Darko; Langley Kate; Pay Helen M; Govan Catherine F; Norton Nadine; Hamshere Marian L; Owen Michael J; O'Donovan Michael C; Thapar Anita
Association analysis of monoamine oxidase A and attention deficit hyperactivity disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;116B(1):84-9.
2003: van den Bree Marianne B M; Owen Michael J
The future of psychiatric genetics.
Annals of medicine 2003;35(2):122-34.
2002: Dimitrova Albena; Georgieva Lyudmila; Nikolov Ivan; Poriazova Nadejda; Krastev Stefan; Toncheva Draga; Owen Michael J; Kirov George
Major psychiatric disorders and the serotonin transporter gene (SLC6A4): family-based association studies.
Psychiatric genetics 2002;12(3):137-41.
2002: Richards A J; Morgan J; Bearcroft P W P; Pickering E; Owen M J; Holmans P; Williams N; Tysoe C; Pope F M; Snead M P; Hughes H
Vitreoretinopathy with phalangeal epiphyseal dysplasia, a type II collagenopathy resulting from a novel mutation in the C-propeptide region of the molecule.
Journal of medical genetics 2002;39(9):661-5.
2002: Wickham Harvey; Walsh Cathy; Asherson Philip; Gill Mike; Owen Michael J; McGuffin Peter; Murray Robin; Sham Pak
Familiality of clinical characteristics in schizophrenia.
Journal of psychiatric research 2002;36(5):325-9.
2002: Bray N J; Kirov G; Owen R J; Jacobsen N J; Georgieva L; Williams H J; Norton N; Spurlock G; Jones S; Zammit S; O'Donovan M C; Owen M J
Screening the human protocadherin 8 (PCDH8) gene in schizophrenia.
Genes, brain, and behavior 2002;1(3):187-91.
2002: Norton Nadine; Kirov George; Zammit Stan; Jones Gaynor; Jones Susan; Owen Richard; Krawczak Michael; Williams Nigel M; O'Donovan Michael C; Owen Michael J
Schizophrenia and functional polymorphisms in the MAOA and COMT genes: no evidence for association or epistasis.
American journal of medical genetics 2002;114(5):491-6.
2002: Norton Nadine; Williams Nigel M; Williams Hywel J; Spurlock Gillian; Kirov George; Morris Derek W; Hoogendoorn Bastiaan; Owen Michael J; O'Donovan Michael C
Universal, robust, highly quantitative SNP allele frequency measurement in DNA pools.
Human genetics 2002;110(5):471-8.
2002: Georgieva L; Dimitrova A; Nikolov I; Koleva S; Tsvetkova R; Owen M J; Toncheva D; Kirov G
Dopamine transporter gene (DAT1) VNTR polymorphism in major psychiatric disorders: family-based association study in the Bulgarian population.
Acta psychiatrica Scandinavica 2002;105(5):396-9.
2002: Rees Mark I; Lewis Trevor M; Kwok John B J; Mortier Geert R; Govaert Paul; Snell Russell G; Schofield Peter R; Owen Michael J
Hyperekplexia associated with compound heterozygote mutations in the beta-subunit of the human inhibitory glycine receptor (GLRB).
Human molecular genetics 2002;11(7):853-60.
2002: Myers Amanda; Wavrant De-Vrieze Fabienne; Holmans Peter; Hamshere Marian; Crook Richard; Compton Danielle; Marshall Helen; Meyer David; Shears Shantia; Booth Jeremy; Ramic Dzanan; Knowles Heather; Morris John C; Williams Nigel; Norton Nadine; Abraham Richard; Kehoe Pat; Williams Hywel; Rudrasingham Varuni; Rice Francis; Giles Peter; Tunstall Nigel; Jones Lesley; Lovestone Simon; Williams Julie; Owen Michael J; Hardy John; Goate Alison
Full genome screen for Alzheimer disease: stage II analysis.
American journal of medical genetics 2002;114(2):235-44.
2002: Williams N M; Spurlock G; Norton N; Williams H J; Hamshere M L; Krawczak M; Kirov G; Nikolov I; Georgieva L; Jones S; Cardno A G; O'Donovan M C; Owen M J
Mutation screening and LD mapping in the VCFS deleted region of chromosome 22q11 in schizophrenia using a novel DNA pooling approach.
Molecular psychiatry 2002;7(10):1092-100.
2002: West A; Langley K; Hamshere M L; Kent L; Craddock N; Owen M J; O'Donovan M; Thapar A
Evidence to suggest biased phenotypes in children with Attention Deficit Hyperactivity Disorder from completely ascertained trios.
Molecular psychiatry 2002;7(9):962-6.
2002: Williams N M; Bowen T; Spurlock G; Norton N; Williams H J; Hoogendoorn B; Owen M J; O'Donovan M C
Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor.
Molecular psychiatry 2002;7(5):508-14.
2002: Anney R J; Rees M I; Bryan E; Spurlock G; Williams N; Norton N; Williams H; Cardno A; Zammit S; Jones S; Jones G; Hoogendoorn B; Smith K; Hamshere M L; Coleman S; Guy C; O'Donovan M C; Owen M J; Buckland P R
Characterisation, mutation detection, and association analysis of alternative promoters and 5' UTRs of the human dopamine D3 receptor gene in schizophrenia.
Molecular psychiatry 2002;7(5):493-502.
2002: Jones I; Jacobsen N; Green E K; Elvidge G P; Owen M J; Craddock N
Evidence for familial cosegregation of major affective disorder and genetic markers flanking the gene for Darier's disease.
Molecular psychiatry 2002;7(4):424-7.
2002: Williams Nigel M; O'Donovan Michael C; Owen Michael J
Genome scans and microarrays: converging on genes for schizophrenia?
Genome biology 2002;3(4):REVIEWS1011.
2002: Henry J C; van Amelsvoort T; Morris R G; Owen M J; Murphy D G M; Murphy K C
An investigation of the neuropsychological profile in adults with velo-cardio-facial syndrome (VCFS).
Neuropsychologia 2002;40(5):471-8.
2001: Abraham R; Myers A; Wavrant-DeVrieze F; Hamshere M L; Thomas H V; Marshall H; Compton D; Spurlock G; Turic D; Hoogendoorn B; Kwon J M; Petersen R C; Tangalos E; Norton J; Morris J C; Bullock R; Liolitsa D; Lovestone S; Hardy J; Goate A; O'Donovan M; Williams J; Owen M J; Jones L
Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease.
Human genetics 2001;109(6):646-52.
2001: Plomin R; Hill L; Craig I W; McGuffin P; Purcell S; Sham P; Lubinski D; Thompson L A; Fisher P J; Turic D; Owen M J
A genome-wide scan of 1842 DNA markers for allelic associations with general cognitive ability: a five-stage design using DNA pooling and extreme selected groups.
Behavior genetics 2001;31(6):497-509.
2001: Murphy K C; Owen M J
Velo-cardio-facial syndrome: a model for understanding the genetics and pathogenesis of schizophrenia.
The British journal of psychiatry : the journal of mental science 2001;179():397-402.
2001: Kirov G; Lowry C A; Stephens M; Oldfield S; O'Donovan M C; Lightman S L; Owen M J
Screening ABCG1, the human homologue of the Drosophila white gene, for polymorphisms and association with bipolar affective disorder.
Molecular psychiatry 2001;6(6):671-7.
2001: Jones G; Zammit S; Norton N; Hamshere M L; Jones S J; Milham C; Sanders R D; McCarthy G M; Jones L A; Cardno A G; Gray M; Murphy K C; Owen M J
Aggressive behaviour in patients with schizophrenia is associated with catechol-O-methyltransferase genotype.
The British journal of psychiatry : the journal of mental science 2001;179():351-5.
2001: Rees M I; Lewis T M; Vafa B; Ferrie C; Corry P; Muntoni F; Jungbluth H; Stephenson J B; Kerr M; Snell R G; Schofield P R; Owen M J
Compound heterozygosity and nonsense mutations in the alpha(1)-subunit of the inhibitory glycine receptor in hyperekplexia.
Human genetics 2001;109(3):267-70.
2001: Cardno A G; Holmans P A; Rees M I; Jones L A; McCarthy G M; Hamshere M L; Williams N M; Norton N; Williams H J; Fenton I; Murphy K C; Sanders R D; Gray M Y; O'Donovan M C; McGuffin P; Owen M J
A genomewide linkage study of age at onset in schizophrenia.
American journal of medical genetics 2001;105(5):439-45.
2001: Sklar P; Schwab S G; Williams N M; Daly M; Schaffner S; Maier W; Albus M; Trixler M; Eichhammer P; Lerer B; Hallmayer J; Norton N; Williams H; Zammit S; Cardno A G; Jones S; McCarthy G; Milanova V; Kirov G; O'Donovan M C; Lander E S; Owen M J; Wildenauer D B
Association analysis of NOTCH4 loci in schizophrenia using family and population-based controls.
Nature genetics 2001;28(2):126-8.
2001: Elvidge G; Jones I; McCandless F; Asherson P; Owen M J; Craddock N
Allelic variation of a BalI polymorphism in the DRD3 gene does not influence susceptibility to bipolar disorder: results of analysis and meta-analysis.
American journal of medical genetics 2001;105(4):307-11.
2001: van Amelsvoort T; Daly E; Robertson D; Suckling J; Ng V; Critchley H; Owen M J; Henry J; Murphy K C; Murphy D G
Structural brain abnormalities associated with deletion at chromosome 22q11: quantitative neuroimaging study of adults with velo-cardio-facial syndrome.
The British journal of psychiatry : the journal of mental science 2001;178():412-9.
2001: Bowen T; Williams N; Norton N; Spurlock G; Wittekindt O H; Morris-Rosendahl D J; Williams H; Brzustowicz L; Hoogendoorn B; Zammit S; Jones G; Sanders R D; Jones L A; McCarthy G; Jones S; Bassett A; Cardno A G; Owen M J; O'Donovan M C
Mutation screening of the KCNN3 gene reveals a rare frameshift mutation.
Molecular psychiatry 2001;6(3):259-60.
2001: Jacobsen N J; Elvidge G; Franks E K; O'Donovan M C; Craddock N; Owen M J
CUX2, a potential regulator of NCAM expression: genomic characterization and analysis as a positional candidate susceptibility gene for bipolar disorder.
American journal of medical genetics 2001;105(3):295-300.
2001: Bray N J; Owen M J
Searching for schizophrenia genes.
Trends in molecular medicine 2001;7(4):169-74.
2001: Jones L A; Cardno A G; Sanders R D; Owen M J; Williams J
Sustained and selective attention as measures of genetic liability to schizophrenia.
Schizophrenia research 2001;48(2-3):263-72.
2001: Wickham H; Walsh C; Asherson P; Taylor C; Sigmundson T; Gill M; Owen M J; McGuffin P; Murray R; Sham P
Familiality of symptom dimensions in schizophrenia.
Schizophrenia research 2001;47(2-3):223-32.
2001: Turic D; Fisher P J; Plomin R; Owen M J
No association between apolipoprotein E polymorphisms and general cognitive ability in children.
Neuroscience letters 2001;299(1-2):97-100.
2001: Jacobsen N J; Franks E K; Elvidge G; Jones I; McCandless F; O'Donovan M C; Owen M J; Craddock N
Exclusion of the Darier's disease gene, ATP2A2, as a common susceptibility gene for bipolar disorder.
Molecular psychiatry 2001;6(1):92-7.
2001: Liddell M B; Lovestone S; Owen M J
Genetic risk of Alzheimer's disease: advising relatives.
The British journal of psychiatry : the journal of mental science 2001;178(1):7-11.
2000: Bowen T; Ashworth L; Kirov G; Guy C A; Jones I R; McCandless F; Craddock N; O'Donovan M C; Owen M J
No evidence of association from transmission disequilibrium analysis of the hKCa3 gene in bipolar disorder.
Bipolar disorders 2000;2(4):328-31.
2000: Myers A; Holmans P; Marshall H; Kwon J; Meyer D; Ramic D; Shears S; Booth J; DeVrieze F W; Crook R; Hamshere M; Abraham R; Tunstall N; Rice F; Carty S; Lillystone S; Kehoe P; Rudrasingham V; Jones L; Lovestone S; Perez-Tur J; Williams J; Owen M J; Hardy J; Goate A M
Susceptibility locus for Alzheimer's disease on chromosome 10.
Science (New York, N.Y.) 2000;290(5500):2304-5.
2000: Vincent J B; Yuan Q P; Schalling M; Adolfsson R; Azevedo M H; Macedo A; Bauer A; DallaTorre C; Medeiros H M; Pato M T; Pato C N; Bowen T; Guy C A; Owen M J; O'Donovan M C; Paterson A D; Petronis A; Kennedy J L
Long repeat tracts at SCA8 in major psychosis.
American journal of medical genetics 2000;96(6):873-6.
2000: Hoogendoorn B; Norton N; Kirov G; Williams N; Hamshere M L; Spurlock G; Austin J; Stephens M K; Buckland P R; Owen M J; O'Donovan M C
Cheap, accurate and rapid allele frequency estimation of single nucleotide polymorphisms by primer extension and DHPLC in DNA pools.
Human genetics 2000;107(5):488-93.
2000: Jones L A; Cardno A G; Murphy K C; Sanders R D; Gray M Y; McCarthy G; McGuffin P; Owen M J; Williams J
The kings schizotypy questionnaire as a quantitative measure of schizophrenia liability.
Schizophrenia research 2000;45(3):213-21.
2000: Austin J; Buckland P; Cardno A G; Williams N; Spurlock G; Hoogendoorn B; Zammit S; Jones G; Sanders R; Jones L; McCarthy G; Jones S; Bray N J; McGuffin P; Owen M J; O'Donovan M C
The high affinity neurotensin receptor gene (NTSR1): comparative sequencing and association studies in schizophrenia.
Molecular psychiatry 2000;5(5):552-7.
2000: Bray N J; Williams N M; Bowen T; Cardno A G; Gray M; Jones L A; Murphy K C; Sanders R D; Spurlock G; Odonovan M C; Owen M J
No evidence for association between a non-synonymous polymorphism in the gene encoding human metabotropic glutamate receptor 7 and schizophrenia.
Psychiatric genetics 2000;10(2):83-6.
2000: Deb S; Braganza J; Norton N; Williams H; Kehoe P G; Williams J; Owen M J
APOE epsilon 4 influences the manifestation of Alzheimer's disease in adults with Down's syndrome.
The British journal of psychiatry : the journal of mental science 2000;176():468-72.
2000: Speight G; Turic D; Austin J; Hoogendoorn B; Cardno A G; Jones L; Murphy K C; Sanders R; McCarthy G; Jones I; McCandless F; McGuffin P; Craddock N; Owen M J; Buckland P; O'Donovan M C
Comparative sequencing and association studies of aromatic L-amino acid decarboxylase in schizophrenia and bipolar disorder.
Molecular psychiatry 2000;5(3):327-31.
2000: Middle F; Jones I; McCandless F; Barrett T; Khanim F; Owen M J; Lendon C; Craddock N
Bipolar disorder and variation at a common polymorphism (A1832G) within exon 8 of the Wolfram gene.
American journal of medical genetics 2000;96(2):154-7.
2000: Austin J; Hoogendoorn B; Buckland P; Jones I; McCandless F; Williams N; Middle F; Owen M J; Craddock N; O'Donovan M C
Association analysis of the proneurotensin gene and bipolar disorder.
Psychiatric genetics 2000;10(1):51-4.
2000: Bowen T; Guy C A; Cardno A G; Vincent J B; Kennedy J L; Jones L A; Gray M; Sanders R D; McCarthy G; Murphy K C; Owen M J; O'Donovan M C
Repeat sizes at CAG/CTG loci CTG18.1, ERDA1 and TGC13-7a in schizophrenia.
Psychiatric genetics 2000;10(1):33-7.
2000: Austin J; Hoogendoorn B; Buckland P; Speight G; Cardno A; Bowen T; Williams N; Spurlock G; Sanders R; Jones L; Murphy K; McCarthy G; McGuffin P; Owen M J; O'Donovan M C
Comparative sequencing of the proneurotensin gene and association studies in schizophrenia.
Molecular psychiatry 2000;5(2):208-12.
2000: Morris D W; Robinson L; Turic D; Duke M; Webb V; Milham C; Hopkin E; Pound K; Fernando S; Easton M; Hamshere M; Williams N; McGuffin P; Stevenson J; Krawczak M; Owen M J; O'Donovan M C; Williams J
Family-based association mapping provides evidence for a gene for reading disability on chromosome 15q.
Human molecular genetics 2000;9(5):843-8.
2000: Tunstall N; Owen M J; Williams J; Rice F; Carty S; Lillystone S; Fraser L; Kehoe P; Neill D; Rudrasingham V; Sham P; Lovestone S
Familial influence on variation in age of onset and behavioural phenotype in Alzheimer's disease.
The British journal of psychiatry : the journal of mental science 2000;176():156-9.
2000: Rees M I; Watts P; Fenton I; Clarke A; Snell R G; Owen M J; Gray J
Further evidence of autosomal dominant congenital zonular pulverulent cataracts linked to 13q11 (CZP3) and a novel mutation in connexin 46 (GJA3).
Human genetics 2000;106(2):206-9.
2000: Owen M J; Cardno A G; O'Donovan M C
Psychiatric genetics: back to the future.
Molecular psychiatry 2000;5(1):22-31.
2000: Kirov G; Williams N; Sham P; Craddock N; Owen M J
Pooled genotyping of microsatellite markers in parent-offspring trios.
Genome research 2000;10(1):105-15.
1999: Kirov G; Jones I; McCandless F; Craddock N; Owen M J
Family-based association studies of bipolar disorder with candidate genes involved in dopamine neurotransmission: DBH, DAT1, COMT, DRD2, DRD3 and DRD5.
Molecular psychiatry 1999;4(6):558-65.
1999: Murphy K C; Jones L A; Owen M J
High rates of schizophrenia in adults with velo-cardio-facial syndrome.
Archives of general psychiatry 1999;56(10):940-5.
1999: Williams H J; Bray N; Murphy K C; Cardno A G; Jones L A; Owen M J
No evidence for allelic association between schizophrenia and a functional variant of the human dopamine beta-hydroxylase gene (DBH).
American journal of medical genetics 1999;88(5):557-9.
1999: Bowen T; Kirov G; Gill M; Spurlock G; Vallada H P; Murray R M; McGuffin P; Collier D A; Owen M J; Craddock N
Linkage studies of bipolar disorder with chromosome 18 markers.
American journal of medical genetics 1999;88(5):503-9.
1999: Kirov G; Rees M; Jones I; MacCandless F; Owen M J; Craddock N
Bipolar disorder and the serotonin transporter gene: a family-based association study.
Psychological medicine 1999;29(5):1249-54.
1999: O'Donovan M C; Owen M J
Candidate-gene association studies of schizophrenia.
American journal of human genetics 1999;65(3):587-92.
1999: Williams N M; Rees M I; Holmans P; Norton N; Cardno A G; Jones L A; Murphy K C; Sanders R D; McCarthy G; Gray M Y; Fenton I; McGuffin P; Owen M J
A two-stage genome scan for schizophrenia susceptibility genes in 196 affected sibling pairs.
Human molecular genetics 1999;8(9):1729-39.
1999: Jacobsen N J; Lyons I; Hoogendoorn B; Burge S; Kwok P Y; O'Donovan M C; Craddock N; Owen M J
ATP2A2 mutations in Darier's disease and their relationship to neuropsychiatric phenotypes.
Human molecular genetics 1999;8(9):1631-6.
1999: Guy C A; Bowen T; Jones I; McCandless F; Owen M J; Craddock N; O'Donovan M C
CTG18.1 and ERDA-1 CAG/CTG repeat size in bipolar disorder.
Neurobiology of disease 1999;6(4):302-7.
1999: Rees M I; Fenton I; Williams N M; Holmans P; Norton N; Cardno A; Asherson P; Spurlock G; Roberts E; Parfitt E; Mant R; Vallada H; Dawson E; Li M W; Collier D A; Powell J F; Nanko S; Gill M; McGuffin P; Owen M J
Autosome search for schizophrenia susceptibility genes in multiply affected families.
Molecular psychiatry 1999;4(4):353-9.
1999: Wavrant-De Vrièze F; Crook R; Holmans P; Kehoe P; Owen M J; Williams J; Roehl K; Laliiri D K; Shears S; Booth J; Wu W; Goate A; Chartier-Harlin M C; Hardy J; Pérez-Tur J
Genetic variability at the amyloid-beta precursor protein locus may contribute to the risk of late-onset Alzheimer's disease.
Neuroscience letters 1999;269(2):67-70.
1999: Cardno A G; Bowen T; Guy C A; Jones L A; McCarthy G; Williams N M; Murphy K C; Spurlock G; Gray M; Sanders R D; Craddock N; McGuffin P; Owen M J; O'Donovan M C
CAG repeat length in the hKCa3 gene and symptom dimensions in schizophrenia.
Biological psychiatry 1999;45(12):1592-6.
1999: Jacobsen N J; Franks E K; Owen M J; Craddock N J
Mutational analysis of phospholipase A2A: a positional candidate susceptibility gene for bipolar disorder.
Molecular psychiatry 1999;4(3):274-9.
1999: Rudrasingham V; Wavrant-De Vrièze F; Lambert J C; Chakraverty S; Kehoe P; Crook R; Amouyel P; Wu W; Rice F; Pérez-Tur J; Frigard B; Morris J C; Carty S; Petersen R; Cottel D; Tunstall N; Holmans P; Lovestone S; Chartier-Harlin M C; Goate A; Hardy J; Owen M J; Williams J
Alpha-2 macroglobulin gene and Alzheimer disease.
Nature genetics 1999;22(1):17-9; author reply 21-2.
1999: Fisher P J; Turic D; Williams N M; McGuffin P; Asherson P; Ball D; Craig I; Eley T; Hill L; Chorney K; Chorney M J; Benbow C P; Lubinski D; Plomin R; Owen M J
DNA pooling identifies QTLs on chromosome 4 for general cognitive ability in children.
Human molecular genetics 1999;8(5):915-22.
1999: Hill L; Craig I W; Asherson P; Ball D; Eley T; Ninomiya T; Fisher P J; Turic D; McGuffin P; Owen M J; Chorney K; Chorney M J; Benbow C P; Lubinski D; Thompson L A; Plomin R
DNA pooling and dense marker maps: a systematic search for genes for cognitive ability.
Neuroreport 1999;10(4):843-8.
1999: Wavrant-DeVrièze F; Rudrasingham V; Lambert J C; Chakraverty S; Kehoe P; Crook R; Amouyel P; Wu W; Holmans P; Rice F; Pérez-Tur J; Frigard B; Morris J C; Carty S; Cottel D; Tunstall N; Lovestone S; Petersen R C; Chartier-Harlin M C; Goate A; Owen M J; Williams J; Hardy J
No association between the alpha-2 macroglobulin I1000V polymorphism and Alzheimer's disease.
Neuroscience letters 1999;262(2):137-9.
1999: Kehoe P; Krawczak M; Harper P S; Owen M J; Jones A L
Age of onset in Huntington disease: sex specific influence of apolipoprotein E genotype and normal CAG repeat length.
Journal of medical genetics 1999;36(2):108-11.
1999: Franks E; Guy C; Jacobsen N; Bowen T; Owen M J; O'Donovan M C; Craddock N
Eleven trinucleotide repeat loci that map to chromosome 12 excluded from involvement in the pathogenesis of bipolar disorder.
American journal of medical genetics 1999;88(1):67-70.
1999: Guy C A; Bowen T; Williams N; Jones I R; McCandless F; McGuffin P; Owen M J; Craddock N; O'Donovan M C
No association between a polymorphic CAG repeat in the human potassium channel gene hKCa3 and bipolar disorder.
American journal of medical genetics 1999;88(1):57-60.
1999: Kehoe P; Wavrant-De Vrieze F; Crook R; Wu W S; Holmans P; Fenton I; Spurlock G; Norton N; Williams H; Williams N; Lovestone S; Perez-Tur J; Hutton M; Chartier-Harlin M C; Shears S; Roehl K; Booth J; Van Voorst W; Ramic D; Williams J; Goate A; Hardy J; Owen M J
A full genome scan for late onset Alzheimer's disease.
Human molecular genetics 1999;8(2):237-45.
1999: Hoogendoorn B; Owen M J; Oefner P J; Williams N; Austin J; O'Donovan M C
Genotyping single nucleotide polymorphisms by primer extension and high performance liquid chromatography.
Human genetics 1999;104(1):89-93.
1999: Kehoe P G; Russ C; McIlory S; Williams H; Holmans P; Holmes C; Liolitsa D; Vahidassr D; Powell J; McGleenon B; Liddell M; Plomin R; Dynan K; Williams N; Neal J; Cairns N J; Wilcock G; Passmore P; Lovestone S; Williams J; Owen M J
Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease.
Nature genetics 1999;21(1):71-2.
1999: Kirov G; Owen M J; Jones I; McCandless F; Craddock N
Tryptophan hydroxylase gene and manic-depressive illness.
Archives of general psychiatry 1999;56(1):98-9.
1999: Cardno A G; Jones L A; Murphy K C; Sanders R D; Asherson P; Owen M J; McGuffin P
Dimensions of psychosis in affected sibling pairs.
Schizophrenia bulletin 1999;25(4):841-50.
1998: Kehoe P G; Williams H; Holmans P; Wilcock G; Cairns N J; Neal J; Owen M J
The butyrylcholinesterase K variant and susceptibility to Alzheimer's disease.
Journal of medical genetics 1998;35(12):1034-5.
1998: Wu W S; Holmans P; Wavrant-DeVrièze F; Shears S; Kehoe P; Crook R; Booth J; Williams N; Pérez-Tur J; Roehl K; Fenton I; Chartier-Harlin M C; Lovestone S; Williams J; Hutton M; Hardy J; Owen M J; Goate A
Genetic studies on chromosome 12 in late-onset Alzheimer disease.
JAMA : the journal of the American Medical Association 1998;280(7):619-22.
1998: Cardno A G; Jones L A; Murphy K C; Sanders R D; Asherson P; Owen M J; McGuffin P
Sibling pairs with schizophrenia or schizoaffective disorder: associations of subtypes, symptoms and demographic variables.
Psychological medicine 1998;28(4):815-23.
1998: Wright P; Dawson E; Donaldson P T; Underhill J A; Sham P C; Zhao J; Gill M; Nanko S; Owen M J; McGuffin P; Murray R M
A transmission/disequilibrium study of the DRB1*04 gene locus on chromosome 6p21.3 with schizophrenia.
Schizophrenia research 1998;32(2):75-80.
1998: Kirov G; Murphy K C; Arranz M J; Jones I; McCandles F; Kunugi H; Murray R M; McGuffin P; Collier D A; Owen M J; Craddock N
Low activity allele of catechol-O-methyltransferase gene associated with rapid cycling bipolar disorder.
Molecular psychiatry 1998;3(4):342-5.
1998: Asherson P; Mant R; Williams N; Cardno A; Jones L; Murphy K; Collier D A; Nanko S; Craddock N; Morris S; Muir W; Blackwood B; McGuffin P; Owen M J
A study of chromosome 4p markers and dopamine D5 receptor gene in schizophrenia and bipolar disorder.
Molecular psychiatry 1998;3(4):310-20.
1998: Bowen T; Guy C A; Craddock N; Cardno A G; Williams N M; Spurlock G; Murphy K C; Jones L A; Gray M; Sanders R D; McCarthy G; Chandy K G; Fantino E; Kalman K; Gutman G A; Gargus J J; Williams J; McGuffin P; Owen M J; O'Donovan M C
Further support for an association between a polymorphic CAG repeat in the hKCa3 gene and schizophrenia.
Molecular psychiatry 1998;3(3):266-9.
1998: Daniels J; Holmans P; Williams N; Turic D; McGuffin P; Plomin R; Owen M J
A simple method for analyzing microsatellite allele image patterns generated from DNA pools and its application to allelic association studies.
American journal of human genetics 1998;62(5):1189-97.
1998: Daniels J; McGuffin P; Owen M J; Plomin R
Molecular genetic studies of cognitive ability.
Human biology; an international record of research 1998;70(2):281-96.
1998: Williams J; Spurlock G; Holmans P; Mant R; Murphy K; Jones L; Cardno A; Asherson P; Blackwood D; Muir W; Meszaros K; Aschauer H; Mallet J; Laurent C; Pekkarinen P; Seppala J; Stefanis C N; Papadimitriou G N; Macciardi F; Verga M; Pato C; Azevedo H; Crocq M A; Gurling H; Owen M J
A meta-analysis and transmission disequilibrium study of association between the dopamine D3 receptor gene and schizophrenia.
Molecular psychiatry 1998;3(2):141-9.
1998: Cardno A G; Murphy K C; Jones L A; Cobb A M; Gray J; McGuffin P; Owen M J
Polydactyly and psychosis. Five cases of co-occurrence.
The British journal of psychiatry : the journal of mental science 1998;172():184-5.
1998: Murphy K C; Jones R G; Griffiths E; Thompson P W; Owen M J
Chromosome 22qII deletions. An under-recognised cause of idiopathic learning disability.
The British journal of psychiatry : the journal of mental science 1998;172():180-3.
1998: Spurlock G; Williams J; McGuffin P; Aschauer H N; Lenzinger E; Fuchs K; Sieghart W C; Meszaros K; Fathi N; Laurent C; Mallet J; Macciardi F; Pedrini S; Gill M; Hawi Z; Gibson S; Jazin E E; Yang H T; Adolfsson R; Pato C N; Dourado A M; Owen M J
European Multicentre Association Study of Schizophrenia: a study of the DRD2 Ser311Cys and DRD3 Ser9Gly polymorphisms.
American journal of medical genetics 1998;81(1):24-8.
1998: Bowen T; Norton N; Jacobsen N J; Guy C; Daniels J K; Sanders R D; Cardno A G; Jones L A; Murphy K C; McGuffin P; Craddock N; O'Donovan M C; Owen M J
Linked polymorphisms upstream of exons 1 and 2 of the human cholecystokinin gene are not associated with schizophrenia or bipolar disorder.
Molecular psychiatry 1998;3(1):67-71.
1998: Arranz M J; Munro J; Owen M J; Spurlock G; Sham P C; Zhao J; Kirov G; Collier D A; Kerwin R W
Evidence for association between polymorphisms in the promoter and coding regions of the 5-HT2A receptor gene and response to clozapine.
Molecular psychiatry 1998;3(1):61-6.
1998: Spurlock G; Heils A; Holmans P; Williams J; D'Souza U M; Cardno A; Murphy K C; Jones L; Buckland P R; McGuffin P; Lesch K P; Owen M J
A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter.
Molecular psychiatry 1998;3(1):42-9.
1998: Owen M J; Craddock N
Chromosome 11 workshop.
Psychiatric genetics 1998;8(2):89-92.
1998: Cardno A G; McCandless F; Bowen T; Guy C A; Jones L A; Murphy K C; McGuffin P; Owen M J; Craddock N; O'Donovan M C
Association between functional psychosis and expanded CAG/CTG repeats is not explained by health stratification.
Psychiatric genetics 1998;8(1):29-32.
1997: Craddock N; McKeon P; Moorhead S; Guy C; Harrison D; Mynett-Johnson L; Claffey E; Feldman E; McGuffin P; Owen M J; O'Donovan M C
Expanded CAG/CTG repeats in bipolar disorder: no correlation with phenotypic measures of illness severity.
Biological psychiatry 1997;42(10):876-81.
1997: Rees M; Norton N; Jones I; McCandless F; Scourfield J; Holmans P; Moorhead S; Feldman E; Sadler S; Cole T; Redman K; Farmer A; McGuffin P; Owen M J; Craddock N
Association studies of bipolar disorder at the human serotonin transporter gene (hSERT; 5HTT).
Molecular psychiatry 1997;2(5):398-402.
1997: Guy C; Bowen T; Daniels J K; Speight G; McKeon P; Mynett-Johnson L; Claffey E; McGuffin P; Owen M J; Craddock N; O'Donovan M C
Exclusion of expansion of 50 CAG/CTG trinucleotide repeats in bipolar disorder.
The American journal of psychiatry 1997;154(8):1146-7.
1997: Daniels J K; Spurlock G; Williams N M; Cardno A G; Jones L A; Murphy K C; Asherson P; Holmans P; Fenton I; McGuffin P; Owen M J
Linkage study of chromosome 6p in sib-pairs with schizophrenia.
American journal of medical genetics 1997;74(3):319-23.
1997: Speight G; Guy C; Bowen T; Asherson P; McGuffin P; Craddock N; Owen M J; O'Donovan M C
Exclusion of CAG/CTG trinucleotide repeat loci which map to chromosome 4 in bipolar disorder and schizophrenia.
American journal of medical genetics 1997;74(2):204-6.
1997: Andrew M; Owen M J
Hyperekplexia: abnormal startle response due to glycine receptor mutations.
The British journal of psychiatry : the journal of mental science 1997;170():106-8.
1997: Cardno A G; Holmans P A; Harvey I; Williams M B; Owen M J; McGuffin P
Factor-derived subsyndromes of schizophrenia and familial morbid risks.
Schizophrenia research 1997;23(3):231-8.
1997: Williams N M; Jones L A; Murphy K C; Cardno A G; Asherson P; Williams J; McGuffin P; Owen M J
No evidence for an allelic association between schizophrenia and markers D22S278 and D22S283.
American journal of medical genetics 1997;74(1):37-9.
1997: Williams N M; Cardno A G; Murphy K C; Jones L A; Asherson P; McGuffin P; Owen M J
Association between schizophrenia and a microsatellite polymorphism at the dopamine D5 receptor gene.
Psychiatric genetics 1997;7(2):83-5.
1996: O'Donovan M C; Owen M J
The molecular genetics of schizophrenia.
Annals of medicine 1996;28(6):541-6.
1996: Cardno A G; Jones L A; Murphy K C; Asherson P; Scott L C; Williams J; Owen M J; McGuffin P
Factor analysis of schizophrenic symptoms using the OPCRIT checklist.
Schizophrenia research 1996;22(3):233-9.
1996: Cardno A G; Murphy K C; Jones L A; Guy C A; Asherson P; De Azevedo M H; Coelho I M; de Macedo e Santos A J; Pato C N; McGuffin P; Owen M J; O'Donovan M C
Expanded CAG/CTG repeats in schizophrenia. A study of clinical correlates.
The British journal of psychiatry : the journal of mental science 1996;169(6):766-71.
1996: O'Donovan M C; Guy C; Craddock N; Bowen T; McKeon P; Macedo A; Maier W; Wildenauer D; Aschauer H N; Sorbi S; Feldman E; Mynett-Johnson L; Claffey E; Nacmias B; Valente J; Dourado A; Grassi E; Lenzinger E; Heiden A M; Moorhead S; Harrison D; Williams J; McGuffin P; Owen M J
Confirmation of association between expanded CAG/CTG repeats and both schizophrenia and bipolar disorder.
Psychological medicine 1996;26(6):1145-53.
1996: Kunugi H; Curtis D; Vallada H P; Nanko S; Powell J F; Murray R M; McGuffin P; Owen M J; Gill M; Collier D A
A linkage study of schizophrenia with DNA markers from chromosome 8p21-p22 in 25 multiplex families.
Schizophrenia research 1996;22(1):61-8.
1996: Bowen T; Guy C; Speight G; Jones L; Cardno A; Murphy K; McGuffin P; Owen M J; O'Donovan M C
Expansion of 50 CAG/CTG repeats excluded in schizophrenia by application of a highly efficient approach using repeat expansion detection and a PCR screening set.
American journal of human genetics 1996;59(4):912-7.
1996: Kehoe P; Williams J; Holmans P; Liddell M; Lovestone S; Holmes C; Powell J; Neal J; Wilcock G; Owen M J
Association between a PS-1 intronic polymorphism and late onset Alzheimer's disease.
Neuroreport 1996;7(13):2155-8.
1996: Craddock M; Asherson P; Owen M J; Williams J; McGuffin P; Farmer A E
Concurrent validity of the OPCRIT diagnostic system. Comparison of OPCRIT diagnoses with consensus best-estimate lifetime diagnoses.
The British journal of psychiatry : the journal of mental science 1996;169(1):58-63.
1996: Asherson P; Mant R; Holmans P; Williams J; Cardno A; Murphy K; Jones L; Collier D; McGuffin P; Owen M J
Linkage, association and mutational analysis of the dopamine D3 receptor gene in schizophrenia.
Molecular psychiatry 1996;1(2):125-32.
1996: Williams J; Spurlock G; McGuffin P; Mallet J; Nöthen M M; Gill M; Aschauer H; Nylander P O; Macciardi F; Owen M J
Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene. European Multicentre Association Study of Schizophrenia (EMASS) Group.
Lancet 1996;347(9011):1294-6.
1996: Kehoe P; Williams J; Lovestone S; Wilcock G; Owen M J
Presenilin-1 polymorphism and Alzheimer's disease. The UK Alzheimer's Disease Collaborative Group.
Lancet 1996;347(9009):1185.
1996: Craddock N; Daniels J; Holmans P; Williams N; Owen M J
Increasing the efficiency of genomic searches for linkage in complex disorders by DNA pooling of affected sib-pairs.
Molecular psychiatry 1996;1(1):59-64.
1996: Owen M J; Craddock N
Modern molecular genetic approaches to complex traits: implications for psychiatric disorders.
Molecular psychiatry 1996;1(1):21-6.
1996: Daniels J K; Williams N M; Williams J; Jones L A; Cardno A G; Murphy K C; Spurlock G; Riley B; Scambler P; Asherson P; McGuffin P; Owen M J
No evidence for allelic association between schizophrenia and a polymorphism determining high or low catechol O-methyltransferase activity.
The American journal of psychiatry 1996;153(2):268-70.
1996: Jacobsen N; Daniels J; Moorhead S; Harrison D; Feldman E; McGuffin P; Owen M J; Craddock N
Association study of bipolar disorder at the phospholipase A2 gene (PLA2A) in the Darier's disease (DAR) region of chromosome 12q23-q24.1.
Psychiatric genetics 1996;6(4):195-9.
1995: Roberts A G; Whatley S D; Daniels J; Holmans P; Fenton I; Owen M J; Thompson P; Long C; Elder G H
Partial characterization and assignment of the gene for protoporphyrinogen oxidase and variegate porphyria to human chromosome 1q23.
Human molecular genetics 1995;4(12):2387-90.
1995: McGuffin P; Owen M J; Farmer A E
Genetic basis of schizophrenia.
Lancet 1995;346(8976):678-82.
1995: Craddock N; Daniels J; Roberts E; Rees M; McGuffin P; Owen M J
No evidence for allelic association between bipolar disorder and monoamine oxidase A gene polymorphisms.
American journal of medical genetics 1995;60(4):322-4.
1995: Liddell M B; Bayer A J; Owen M J
No evidence that common allelic variation in the Amyloid Precursor Protein (APP) gene confers susceptibility to Alzheimer's disease.
Human molecular genetics 1995;4(5):853-8.
1995: Craddock N; Roberts Q; Williams N; McGuffin P; Owen M J
Association study of bipolar disorder using a functional polymorphism (Ser311-->Cys) in the dopamine D2 receptor gene.
Psychiatric genetics 1995;5(2):63-5.
1994: Rees M I; Andrew M; Jawad S; Owen M J
Evidence for recessive as well as dominant forms of startle disease (hyperekplexia) caused by mutations in the alpha 1 subunit of the inhibitory glycine receptor.
Human molecular genetics 1994;3(12):2175-9.
1994: Daniels J; Williams J; Mant R; Asherson P; McGuffin P; Owen M J
Repeat length variation in the dopamine D4 receptor gene shows no evidence of association with schizophrenia.
American journal of medical genetics 1994;54(3):256-8.
1994: Thapar A; Gottesman I I; Owen M J; O'Donovan M C; McGuffin P
The genetics of mental retardation.
The British journal of psychiatry : the journal of mental science 1994;164(6):747-58.
1994: Mant R; Williams J; Asherson P; Parfitt E; McGuffin P; Owen M J
Relationship between homozygosity at the dopamine D3 receptor gene and schizophrenia.
American journal of medical genetics 1994;54(1):21-6.
1992: Owen M J; Mant R; Parfitt E; Williams J; Asherson P; O'Mahoney G; Van Os J; Llewellyn D; Collier D; Gill M
No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia.
Human genetics 1992;90(1-2):131-2.
1992: O'Donovan M C; Owen M J
Advances and retreats in the molecular genetics of major mental illness.
Annals of medicine 1992;24(3):171-7.
1991: Owen M J; Goate A M; Hardy J A
A polymorphic microsatellite repeat sequence on chromosome 21 (D21S80).
Nucleic acids research 1991;19(16):4574.
1991: Mullan M J; Giuffra L; Hardy J A; Ovenstone I; Haynes A R; James L A; Williamson R; Newton P J; Owen M J; Roques P
Clinical and pathologic features of chromosome 21-linked familial Alzheimer's disease.
Annals of the New York Academy of Sciences 1991;640():177-80.
1990: Owen M J; James L A; Hardy J A; Williamson R; Goate A M
Physical mapping around the Alzheimer disease locus on the proximal long arm of chromosome 21.
American journal of human genetics 1990;46(2):316-22.
1990: Owen M J; Mullan M J
Molecular genetic studies of manic-depression and schizophrenia.
Trends in neurosciences 1990;13(1):29-31.
1990: Goate A M; Hardy J A; Owen M J; Haynes A; James L; Farrall M; Mullan M J; Roques P; Rossor M N
Genetics of Alzheimer's disease.
Advances in neurology 1990;51():197-8.
1989: Hardy J A; Goate A M; Owen M J; Mullan M J; Rossor M N; Pearson R C
Modelling the occurrence and pathology of Alzheimer's disease.
Neurobiology of aging 1989;10(5):429-31; discussion 446-8.
1989: Goate A M; Haynes A R; Owen M J; Farrall M; James L A; Lai L Y; Mullan M J; Roques P; Rossor M N; Williamson R
Predisposing locus for Alzheimer's disease on chromosome 21.
Lancet 1989;1(8634):352-5.
1989: Hardy J A; Owen M J; Goate A M; James L A; Haynes A R; Rossor M N; Roques P; Mullan M J
Molecular genetics of Alzheimer's disease.
Biochemical Society transactions 1989;17(1):75-6.
1988: Owen M J; Whatley S A
Polymorphic DNA markers and mental disease.
Psychological medicine 1988;18(3):529-33.

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