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Whyte Owen

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Myung S Park; Michael G Sarr; Henry J Schiller; Scott P Zietlow; Beth A Ballinger; Mark H Ereth; Donald H Jenkins; Barbara A L Owen; Whyte G Owen; John A Heit
Quantification of hypercoagulable state after blunt trauma: microparticle and thrombin generation are increased relative to injury severity, while standard markers are not.
Gerhard J Johnson; David D Laxson; Gundu H R Rao; Anish V Sharda; Mark H Ereth; Whyte G Owen
Measurement of shear-activated platelet aggregate formation in non-anticoagulated blood: utility in detection of clopidogrel-aspirin-induced platelet dysfunction.
Muthuvel Jayachandran; Brian D Lahr; Robert D Litwiller; Kent R Bailey; S Mitchell Harman; John A Heit; Howard N Hodis; Sharon L Mulvagh; Whyte G Owen; Virginia M Miller
Alterations in platelet function and cell-derived microvesicles in recently menopausal women: relationship to metabolic syndrome and atherogenic risk.

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All Publications

2012: Myung S Park; Michael G Sarr; Henry J Schiller; Scott P Zietlow; Beth A Ballinger; Mark H Ereth; Donald H Jenkins; Barbara A L Owen; Whyte G Owen; John A Heit
Quantification of hypercoagulable state after blunt trauma: microparticle and thrombin generation are increased relative to injury severity, while standard markers are not.
Surgery 2012;151(6):831-6.
2012: Gerhard J Johnson; David D Laxson; Gundu H R Rao; Anish V Sharda; Mark H Ereth; Whyte G Owen
Measurement of shear-activated platelet aggregate formation in non-anticoagulated blood: utility in detection of clopidogrel-aspirin-induced platelet dysfunction.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2012;18(2):140-9.
2011: Muthuvel Jayachandran; Brian D Lahr; Robert D Litwiller; Kent R Bailey; S Mitchell Harman; John A Heit; Howard N Hodis; Sharon L Mulvagh; Whyte G Owen; Virginia M Miller
Alterations in platelet function and cell-derived microvesicles in recently menopausal women: relationship to metabolic syndrome and atherogenic risk.
Journal of cardiovascular translational research 2011;4(6):811-22.
2011: B A L Owen; A Xue; John A Heit; Whyte G Owen
Procoagulant activity, but not number, of microparticles increases with age and in individuals after a single venous thromboembolism.
Thrombosis research 2011;127(1):39-46.
2010: Rajiv K Pruthi; Todd M Daniels; John A Heit; Dong Chen; Whyte G Owen; William L Nichols
Plasma von Willebrand factor multimer quantitative analysis by in-gel immunostaining and infrared fluorescent imaging.
Thrombosis research 2010;126(6):543-9.
2010: Muthuvel Jayachandran; Virginia M Miller; Gregory J Brunn; Whyte G Owen
Platelet response as a sentinel marker of toll-like receptor 4 activation in mice.
Thrombosis research 2010;126(5):414-7.
2009: Chike Obi; Waldemar Wysokinski; Krzystof Karnicki; Whyte G Owen; Robert D McBane
Inhibition of platelet-rich arterial thrombus in vivo: acute antithrombotic effect of intravenous HMG-CoA reductase therapy.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(9):1271-6.
2009: Kazunori Hashimoto; Muthuvel Jayachandran; Whyte G Owen; Virginia M Miller
Aggregation and microparticle production through toll-like receptor 4 activation in platelets from recently menopausal women.
Journal of cardiovascular pharmacology 2009;54(1):57-62.
2009: Jennifer D Tibodeau; Linda M Benson; Crescent R Isham; Whyte G Owen; Keith C Bible
The anticancer agent chaetocin is a competitive substrate and inhibitor of thioredoxin reductase.
Antioxidants & redox signaling 2009;11(5):1097-106.
2008: Yves Nominé; Maria-Victoria Botuyan; Zeljko Bajzer; Whyte G Owen; Ariel J Caride; Emeric Wasielewski; Georges Mer
Kinetic analysis of interaction of BRCA1 tandem breast cancer c-terminal domains with phosphorylated peptides reveals two binding conformations.
Biochemistry 2008;47(37):9866-79.
2008: Muthuvel Jayachandran; Robert D Litwiller; Whyte G Owen; John A Heit; Thomas Behrenbeck; Sharon L Mulvagh; Philip A Araoz; Matthew J Budoff; S Mitchell Harman; Virginia M Miller
Characterization of blood borne microparticles as markers of premature coronary calcification in newly menopausal women.
American journal of physiology. Heart and circulatory physiology 2008;295(3):H931-H938.
2008: D Chen; C A Daigh; J I Hendricksen; Rajiv K Pruthi; William L Nichols; John A Heit; Whyte G Owen
A highly-sensitive plasma von Willebrand factor ristocetin cofactor (VWF:RCo) activity assay by flow cytometry.
Journal of thrombosis and haemostasis : JTH 2008;6(2):323-30.
2008: Virginia M Miller; Muthuvel Jayachandran; Kazumori Hashimoto; John A Heit; Whyte G Owen
Estrogen, inflammation, and platelet phenotype.
Gender medicine 2008;5 Suppl A():S91-S102.
2007: Virginia M Miller; Muthuvel Jayachandran; Whyte G Owen
Ageing, oestrogen, platelets and thrombotic risk.
Clinical and experimental pharmacology & physiology 2007;34(8):814-21.
2007: Muthuvel Jayachandran; Gregory J Brunn; Krzysztof Karnicki; Randall S Miller; Whyte G Owen; Virginia M Miller
In vivo effects of lipopolysaccharide and TLR4 on platelet production and activity: implications for thrombotic risk.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;102(1):429-33.
2006: Virginia M Miller; Muthuvel Jayachandran; John A Heit; Whyte G Owen
Estrogen therapy and thrombotic risk.
Pharmacology & therapeutics 2006;111(3):792-807.
2006: Gregory A Nuttall; William C Oliver; David N Fass; Whyte G Owen; Devin Dinenno; Mark H Ereth; Brent A Williams; Joseph A Dearani; Hartzell V Schaff
A prospective, randomized platelet-function study of heparinized oxygenators and cardiotomy suction.
Journal of cardiothoracic and vascular anesthesia 2006;20(4):554-61.
2005: Muthuvel Jayachandran; Antonio Sanzo; Whyte G Owen; Virginia M Miller
Estrogenic regulation of tissue factor and tissue factor pathway inhibitor in platelets.
American journal of physiology. Heart and circulatory physiology 2005;289(5):H1908-16.
2005: Muthuvel Jayachandran; Krzysztof Karnicki; Randall S Miller; Whyte G Owen; Kenneth S Korach; Virginia M Miller
Platelet characteristics change with aging: role of estrogen receptor beta.
The journals of gerontology. Series A, Biological sciences and medical sciences 2005;60(7):815-9.
2005: Muthuvel Jayachandran; Rajarshi Mukherjee; Thomas Steinkamp; Peter LaBreche; Margarita P Bracamonte; Hiroya Okano; Whyte G Owen; Virginia M Miller
Differential effects of 17beta-estradiol, conjugated equine estrogen, and raloxifene on mRNA expression, aggregation, and secretion in platelets.
American journal of physiology. Heart and circulatory physiology 2005;288(5):H2355-62.
2005: John A Heit; Tanya M Petterson; Whyte G Owen; James P Burke; Mariza de Andrade; Joseph L Melton
Thrombomodulin gene polymorphisms or haplotypes as potential risk factors for venous thromboembolism: a population-based case-control study.
Journal of thrombosis and haemostasis : JTH 2005;3(4):710-7.
2004: Krzysztof Karnicki; Robert D McBane; Randall S Miller; Robert Leadley; J Morser; Whyte G Owen; James H Chesebro
Inhibition and reversal of platelet-rich arterial thrombus in vivo: direct vs. indirect factor Xa inhibition.
Journal of thrombosis and haemostasis : JTH 2004;2(12):2162-9.
2004: Muthuvel Jayachandran; Hiroya Okano; Ritu Chatrath; Whyte G Owen; Joseph P McConnell; Virginia M Miller
Sex-specific changes in platelet aggregation and secretion with sexual maturity in pigs.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;97(4):1445-52.
2004: Waldemar E Wysokinski; Whyte G Owen; David N Fass; D D Patrzalek; L Murphy; Robert D McBane
Atrial fibrillation and thrombosis: immunohistochemical differences between in situ and embolized thrombi.
Journal of thrombosis and haemostasis : JTH 2004;2(9):1637-44.
2004: Robert D McBane; Krzysztof Karnicki; Randall S Miller; Whyte G Owen
The impact of peripheral arterial disease on circulating platelets.
Thrombosis research 2004;113(2):137-45.
2003: Robert D McBane; Krzysztof Karnicki; NK Tahirkheli; Randall S Miller; Whyte G Owen
Platelet characteristics associated with coronary artery disease.
Journal of thrombosis and haemostasis : JTH 2003;1(6):1296-303.
2003: Whyte G Owen
PAR-3 is a low-affinity substrate, high affinity effector of thrombin.
Biochemical and biophysical research communications 2003;305(1):166-8.
2003: Muthuvel Jayachandran; Whyte G Owen; Virginia M Miller
Effects of ovariectomy on aggregation, secretion, and metalloproteinases in porcine platelets.
American journal of physiology. Heart and circulatory physiology 2003;284(5):H1679-85.
2003: Teresa M Jiménez; Sachin B Patel; Alvaro A Pineda; Ayalew Tefferi; Whyte G Owen
Factors that influence platelet recovery after transfusion: resolving donor quality from ABO compatibility.
Transfusion 2003;43(3):328-34.
2003: ronald go; Erik L Ritman; Whyte G Owen
Angiogenesis in rat aortic rings stimulated by very low concentrations of serum and plasma.
Angiogenesis 2003;6(1):25-9.
2003: ronald go; Whyte G Owen
The rat aortic ring assay for in vitro study of angiogenesis.
Methods in molecular medicine 2003;85():59-64.
2002: Krzysztof Karnicki; Whyte G Owen; Randall S Miller; Robert D McBane
Factors contributing to individual propensity for arterial thrombosis.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(9):1495-9.
2002: Margarita P Bracamonte; Kevin S Rud; Whyte G Owen; Virginia M Miller
Ovariectomy increases mitogens and platelet-induced proliferation of arterial smooth muscle.
American journal of physiology. Heart and circulatory physiology 2002;283(3):H853-60.
2002: Laura A Cassiday; Lori L Lebruska; Linda M Benson; Stephen Naylor; Whyte G Owen; L James Maher
Binding stoichiometry of an RNA aptamer and its transcription factor target.
Analytical biochemistry 2002;306(2):290-7.
2002: Oleksandr Gakh; Jiri Adamec; A Marquis Gacy; Ray D Twesten; Whyte G Owen; Grazia Isaya
Physical evidence that yeast frataxin is an iron storage protein.
Biochemistry 2002;41(21):6798-804.
2002: Krzysztof Karnicki; Erzsébet Komorowicz; David N Fass; Whyte G Owen; Robert D McBane
Influence of anatomical location on arterial thrombosis.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(2):342-7.
2001: M D Luyer; Sundeep Khosla; Whyte G Owen; Virginia M Miller
Prospective randomized study of effects of unopposed estrogen replacement therapy on markers of coagulation and inflammation in postmenopausal women.
The Journal of clinical endocrinology and metabolism 2001;86(8):3629-34.
2000: Jiri Adamec; Frank Rusnak; Whyte G Owen; S Naylor; Linda M Benson; A M Gacy; Grazia Isaya
Iron-dependent self-assembly of recombinant yeast frataxin: implications for Friedreich ataxia.
American journal of human genetics 2000;67(3):549-62.
2000: Robert D McBane; M A Ford; Krzysztof Karnicki; M Stewart; Whyte G Owen
Fibrinogen, fibrin and crosslinking in aging arterial thrombi.
Thrombosis and haemostasis 2000;84(1):83-7.
2000: Robert D McBane; Michelle A Elliott; J G White; J E Charlesworth; M G Costopoulos; Whyte G Owen; William L Nichols
Fechtner syndrome: physiologic analysis of macrothrombocytopenia.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2000;11(3):243-7.
1999: R D Smith; Whyte G Owen
Platelet responses to compound interactions with thrombin.
Biochemistry 1999;38(28):8936-47.
1999: Raymund Machovich; Erzsébet Komorowicz; Kraszimir Nikolaev Kolev; Whyte G Owen
Facilitation of plasminogen activation by denatured prothrombin.
Thrombosis research 1999;94(6):389-94.
1999: Waldemar E Wysokinski; Robert D McBane; Whyte G Owen
Individual propensity for arterial thrombosis.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(4):883-6.
1998: JS Gill; Kelly R Pitts; Frank Rusnak; Whyte G Owen; Anthony J Windebank
Thrombin induced inhibition of neurite outgrowth from dorsal root ganglion neurons.
Brain research 1998;797(2):321-7.
1997: Robert D McBane; Randall S Miller; Nancy L Hassinger; James H Chesebro; Yale Nemerson; Whyte G Owen
Tissue prothrombin. Universal distribution in smooth muscle.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(11):2430-6.
1997: Raymund Machovich; Whyte G Owen
Denatured proteins as cofactors for plasminogen activation.
Archives of biochemistry and biophysics 1997;344(2):343-9.
1997: Raymund Machovich; Katalin Ajtai; Kraszimir Nikolaev Kolev; Whyte G Owen
Myosin as cofactor and substrate in fibrinolysis.
FEBS letters 1997;407(1):93-6.
1996: W Wysokinski; Robert D McBane; J H Chesebro; Whyte G Owen
Reversibility of platelet thrombosis in vivo. Quantitative analysis in porcine carotid arteries.
Thrombosis and haemostasis 1996;76(6):1108-13.
1996: J Bichler; John A Heit; Whyte G Owen
Detection of thrombin in human blood by ex-vivo hirudin.
Thrombosis research 1996;84(4):289-94.
1996: William P Fay; J G Murphy; Whyte G Owen
High concentrations of active plasminogen activator inhibitor-1 in porcine coronary artery thrombi.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(10):1277-84.
1996: AS O'Marcaigh; W L Nichols; Nancy L Hassinger; J D Mullins; A A Mallouh; G S Gilchrist; Whyte G Owen
Genetic analysis and functional characterization of prothrombins Corpus Christi (Arg382-Cys), Dhahran (Arg271-His), and hypoprothrombinemia.
Blood 1996;88(7):2611-8.
1996: Kraszimir Nikolaev Kolev; Erzsébet Komorowicz; Whyte G Owen; Raymund Machovich
Quantitative comparison of fibrin degradation with plasmin, miniplasmin, neurophil leukocyte elastase and cathepsin G.
Thrombosis and haemostasis 1996;75(1):140-6.
1995: Robert D McBane; W E Wysokinski; J H Chesebro; Whyte G Owen
Antithrombotic action of endogenous porcine protein C activated with a latent porcine thrombin preparation.
Thrombosis and haemostasis 1995;74(3):879-85.
1995: Whyte G Owen; J Bichler; D Ericson; W Wysokinski
Gating of thrombin in platelet aggregates by pO2-linked lowering of extracellular Ca2+ concentration.
Biochemistry 1995;34(29):9277-81.
1995: Kraszimir Nikolaev Kolev; Whyte G Owen; Raymund Machovich
Dual effect of synthetic plasmin substrates on plasminogen activation.
Biochimica et biophysica acta 1995;1247(2):239-45.
1994: P Zoldhelyi; J Bichler; Whyte G Owen; Diane E Grill; V Fuster; Jozef S. Mruk; J H Chesebro
Persistent thrombin generation in humans during specific thrombin inhibition with hirudin.
Circulation 1994;90(6):2671-8.
1994: J S Felsch; Whyte G Owen
Endogenous antithrombin associated with microvascular endothelium. Quantitative analysis in perfused rat hearts.
Biochemistry 1994;33(3):818-22.
1993: Raymund Machovich; Whyte G Owen
Facilitation of plasminogen activation by a plasmin substrate containing a lysyl residue.
Thrombosis and haemostasis 1993;70(5):864-6.
1993: P Zoldhelyi; J H Chesebro; Whyte G Owen
Hirudin as a molecular probe for thrombin in vitro and during systemic coagulation in the pig.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(5):1819-23.
1992: Raymund Machovich; R D Litwiller; Whyte G Owen
Requirement of zymogen modification for activation of porcine plasminogen.
Biochemistry 1992;31(46):11558-61.
1990: B A Owen; Whyte G Owen
Interaction of factor Xa with heparin does not contribute to the inhibition of factor Xa by antithrombin III-heparin.
Biochemistry 1990;29(40):9412-7.
1990: Raymund Machovich; Whyte G Owen
6-aminohexanoate and chloride ion in the activation by urokinase of porcine plasminogens.
Biochimica et biophysica acta 1990;1040(1):109-11.
1990: Raymund Machovich; A Himer; Whyte G Owen
Neutrophil proteases in plasminogen activation.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1990;1(3):273-7.
1990: Raymund Machovich; Whyte G Owen
The elastase-mediated pathway of fibrinolysis.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1990;1(1):79-90.
1989: William P Fay; Whyte G Owen
Platelet plasminogen activator inhibitor: purification and characterization of interaction with plasminogen activators and activated protein C.
Biochemistry 1989;28(14):5773-8.