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Yoshio Ozaki

Research Profile

Anatomy

Blood Platelets

Physiology

Phenomena

Phosphorylation

Chemicals & Drugs

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Publications

TOP 3
Yoshio Ozaki; Keiko Shimamoto; Yonsu Son; Akihiro Tanaka; Hideki Amuro; Tomoki Ito; Shosaku Nomura
Effective intravenous immunoglobulin therapy for Churg-Strauss syndrome (allergic granulomatous angiitis) complicated by neuropathy of the eighth cranial nerve: a case report.
Yoshio Ozaki; Keiko Shimamoto; Yonsu Son; Akihiro Tanaka; Takahiko Wada; Hideki Amuro; Tomoki Ito; Katsuyuki Kawakami; Shosaku Nomura
A case of rheumatoid pericarditis associated with a high IL-6 titer in the pericardial fluid and tocilizumab treatment.
Hideki Amuro; Tomoki Ito; Rie Miyamoto; Hiroyuki Sugimoto; Yoshitaro Torii; Yonsu Son; Naoto Nakamichi; Chihiro Yamazaki; Katsuaki Hoshino; Tsuneyasu Kaisho; Yoshio Ozaki; Muneo Inaba; Ryuichi Amakawa; Shirou Fukuhara
Statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, function as inhibitors of cellular and molecular components involved in type I interferon production.

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All Publications

2012: Yoshio Ozaki; Keiko Shimamoto; Yonsu Son; Akihiro Tanaka; Hideki Amuro; Tomoki Ito; Shosaku Nomura
Effective intravenous immunoglobulin therapy for Churg-Strauss syndrome (allergic granulomatous angiitis) complicated by neuropathy of the eighth cranial nerve: a case report.
Journal of medical case reports 2012;6(1):310.
2011: Yoshio Ozaki; Keiko Shimamoto; Yonsu Son; Akihiro Tanaka; Takahiko Wada; Hideki Amuro; Tomoki Ito; Katsuyuki Kawakami; Shosaku Nomura
A case of rheumatoid pericarditis associated with a high IL-6 titer in the pericardial fluid and tocilizumab treatment.
Modern rheumatology / the Japan Rheumatism Association 2011;21(3):302-4.
2010: Hideki Amuro; Tomoki Ito; Rie Miyamoto; Hiroyuki Sugimoto; Yoshitaro Torii; Yonsu Son; Naoto Nakamichi; Chihiro Yamazaki; Katsuaki Hoshino; Tsuneyasu Kaisho; Yoshio Ozaki; Muneo Inaba; Ryuichi Amakawa; Shirou Fukuhara
Statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, function as inhibitors of cellular and molecular components involved in type I interferon production.
Arthritis and rheumatism 2010;62(7):2073-85.
2010: Yoshio Ozaki; Tetsuhide Ito; Y Son; H Amuro; K Shimamoto; H Sugimoto; Y Katashiba; M Ogata; R Miyamoto; N Murakami; Ryuichi Amakawa; Shirou Fukuhara
Decrease of blood dendritic cells and increase of tissue-infiltrating dendritic cells are involved in the induction of Sjögren's syndrome but not in the maintenance.
Clinical and experimental immunology 2010;159(3):315-26.
2009: Yoshio Ozaki; Katsue Suzuki-Inoue; Osamu Inoue
Novel interactions in platelet biology: CLEC-2/podoplanin and laminin/GPVI.
Journal of thrombosis and haemostasis : JTH 2009;7 Suppl 1():191-4.
2009: Yoshiko Shimamoto; Shosaku Nomura; Kazuyoshi Ishii; Michiomi Shimizu; Yoshio Ozaki; Tomoki Ito; Fumiaki Urase; Yasuhiro Maeda; Shirou Fukuhara
Adult T-cell leukemia after immunosuppressive therapy for systemic lupus erythematosus.
International journal of hematology 2009;89(1):128-9.
2008: Keiko Shimamoto; Yoshio Ozaki; Hideki Amuro; Yonsu Son; Maiko Ota-Imamura; Tsutomu Tanijiri; Takashi Yokoi; Yasuhiro Yagi; Tomoki Ito; Seibun Yonezu; Shirou Fukuhara
Three cases of polymyositis/dermatomyositis complicated by pneumomediastinum.
Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology 2008;31(1):56-61.
2008: Tomoki Ito; Yoshio Ozaki; Keiko Shimamoto; Hideki Amuro; Tsutomu Tanijiri; Takashi Yokoi; Yonsu Son; Kenichirou Tajima; Shirou Fukuhara
Successful treatment with plasma exchange in adult-onset Still's disease with hyper-IL-18-naemia and hyperallergic state.
Modern rheumatology / the Japan Rheumatism Association 2008;18(4):407-10.
2007: W Jin; Osamu Inoue; N Tamura; Katsue Suzuki-Inoue; Kaneo Satoh; Michael C Berndt; M Handa; S Goto; Yoshio Ozaki
A role for glycosphingolipid-enriched microdomains in platelet glycoprotein Ib-mediated platelet activation.
Journal of thrombosis and haemostasis : JTH 2007;5(5):1034-40.
2007: Olga Cuyun-Lira; Makoto Kaneko; Toshiro Takafuta; Kaneo Satoh; Masatoshi Ohnishi; Yutaka Yatomi; Yoshio Ozaki
Inhibitory effects of ticlopidine on platelet function as assessed by three different methods.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2007;30(1):21-5.
2006: Yonsu Son; Tomoki Ito; Yoshio Ozaki; Tsutomu Tanijiri; Takashi Yokoi; Kengo Nakamura; Masashi Takebayashi; Ryuichi Amakawa; Shirou Fukuhara
Prostaglandin E2 is a negative regulator on human plasmacytoid dendritic cells.
Immunology 2006;119(1):36-42.
2005: Yoshio Ozaki; Naoki Asazuma; Katsue Suzuki-Inoue; Michael C Berndt
Platelet GPIb-IX-V-dependent signaling.
Journal of thrombosis and haemostasis : JTH 2005;3(8):1745-51.
2005: Tsukasa Ohmori; Yutaka Yatomi; Makoto Osada; Yoshio Ozaki
The intracellular action of sphingosine 1-phosphate in GPVI-mediated Ca2+ mobilization in platelets.
Thrombosis research 2005;115(5):409-15.
2004: Y Naganuma; Kaneo Satoh; Q Yi; Naoki Asazuma; Yutaka Yatomi; Yoshio Ozaki
Cleavage of platelet endothelial cell adhesion molecule-1 (PECAM-1) in platelets exposed to high shear stress.
Journal of thrombosis and haemostasis : JTH 2004;2(11):1998-2008.
2004: M Ota; Ryuichi Amakawa; Kazutaka Uehira; Tomoki Ito; Y Yagi; A Oshiro; Y Date; H Oyaizu; T Shigeki; Yoshio Ozaki; Kazuyuki Yamaguchi; Yoshiko Uemura; Seibun Yonezu; Shirou Fukuhara
Involvement of dendritic cells in sarcoidosis.
Thorax 2004;59(5):408-13.
2004: Yoshio Ozaki; Yonsu Son; Kengo Nakamura; Masashi Takebayashi; Minori Nagahama; Hideo Kagawa; Shirou Fukuhara
Human leukocyte antigen haplotype and autoantibodies of a family with systemic lupus erythematosus.
Modern rheumatology / the Japan Rheumatism Association 2004;14(3):241-4.
2003: Masashi Takebayashi; Yoshio Ozaki; Yonsu Son; Minori Nagahama; Shirou Fukuhara
[Case of vascular Behçet's disease initially presented with Bürger's disease-like vasculitides].
Ryūmachi. [Rheumatism] 2003;43(4):683-9.
2003: Minori Nagahama; Shosaku Nomura; Shigenori Kanazawa; Yoshio Ozaki; Hideo Kagawa; Shirou Fukuhara
Significance of anti-oxidized LDL antibody and monocyte-derived microparticles in anti-phospholipid antibody syndrome.
Autoimmunity 2003;36(3):125-31.
2002: Kazutaka Uehira; Ryuichi Amakawa; Tomoki Ito; Kenichirou Tajima; Shinsuke Naitoh; Yoshio Ozaki; Toshiki Shimizu; Kazuyuki Yamaguchi; Yoshiko Uemura; Hiroyuki Kitajima; Seibun Yonezu; Shirou Fukuhara
Dendritic cells are decreased in blood and accumulated in granuloma in tuberculosis.
Clinical immunology (Orlando, Fla.) 2002;105(3):296-303.
2002: Minori Nagahama; Shosaku Nomura; Shigenori Kanazawa; Yoshio Ozaki; Hideo Kagawa; Shirou Fukuhara
Significance of chemokines and soluble CD40 ligand in patients with autoimmune thrombocytopenic purpura.
European journal of haematology 2002;69(5-6):303-8.
2002: Tomoki Ito; Ryuichi Amakawa; Tsuneyasu Kaisho; Hiroaki Hemmi; Kenichirou Tajima; Kazutaka Uehira; Yoshio Ozaki; Hideyuki Tomizawa; Shizuo Akira; Shirou Fukuhara
Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets.
The Journal of experimental medicine 2002;195(11):1507-12.
2001: Katsue Suzuki-Inoue; Yutaka Yatomi; Naoki Asazuma; M Kainoh; T Tanaka; Kaneo Satoh; Yoshio Ozaki
Rac, a small guanosine triphosphate-binding protein, and p21-activated kinase are activated during platelet spreading on collagen-coated surfaces: roles of integrin alpha(2)beta(1).
Blood 2001;98(13):3708-16.
2001: Tsukasa Ohmori; Yutaka Yatomi; Y Wu; M Osada; Kaneo Satoh; Yoshio Ozaki
Wheat germ agglutinin-induced platelet activation via platelet endothelial cell adhesion molecule-1: involvement of rapid phospholipase C gamma 2 activation by Src family kinases.
Biochemistry 2001;40(43):12992-3001.
2001: Yi Wu; Katsue Suzuki-Inoue; Kaneo Satoh; Naoki Asazuma; Yutaka Yatomi; Michael C Berndt; Yoshio Ozaki
Role of Fc receptor gamma-chain in platelet glycoprotein Ib-mediated signaling.
Blood 2001;97(12):3836-45.
2001: G Rile; Yutaka Yatomi; R Qi; Kaneo Satoh; Yoshio Ozaki
Potentiation of ibudilast inhibition of platelet aggregation in the presence of endothelial cells.
Thrombosis research 2001;102(3):239-46.
2001: Makoto Osada; Tsukasa Ohmori; Yutaka Yatomi; Kaneo Satoh; S Hosogaya; Yoshio Ozaki
Involvement of Hic-5 in platelet activation: integrin alphaIIbbeta3-dependent tyrosine phosphorylation and association with proline-rich tyrosine kinase 2.
The Biochemical journal 2001;355(Pt 3):691-7.
2001: Yutaka Yatomi; Yoshio Ozaki; Tsukasa Ohmori; Y Igarashi
Sphingosine 1-phosphate: synthesis and release.
Prostaglandins & other lipid mediators 2001;64(1-4):107-22.
2001: Yutaka Yatomi; Yoshio Ozaki
[New laboratory tests for detecting platelet abnormalities].
Rinsho byori. The Japanese journal of clinical pathology 2001;Suppl 115():65-73.
2001: Tsukasa Ohmori; Yutaka Yatomi; H Okamoto; Y Miura; Ge Rile; Kaneo Satoh; Yoshio Ozaki
G(i)-mediated Cas tyrosine phosphorylation in vascular endothelial cells stimulated with sphingosine 1-phosphate: possible involvement in cell motility enhancement in cooperation with Rho-mediated pathways.
The Journal of biological chemistry 2001;276(7):5274-80.
2001: Kazutaka Uehira; Ryuichi Amakawa; Tomoki Ito; T Uehira; Yoshio Ozaki; Toshiki Shimizu; M Fujimoto; M Inaba; Shirou Fukuhara
A Hodgkin's disease cell line, KM-H2, shows biphenotypic features of dendritic cells and B cells.
International journal of hematology 2001;73(2):236-44.
2001: Yoshio Ozaki; Ryuichi Amakawa; Tomoki Ito; H Iwai; Kenichirou Tajima; Kazutaka Uehira; H Kagawa; Yoshiko Uemura; T Yamashita; Shirou Fukuhara
Alteration of peripheral blood dendritic cells in patients with primary Sjögren's syndrome.
Arthritis and rheumatism 2001;44(2):419-31.
2001: R Qi; Yutaka Yatomi; Yoshio Ozaki
Effects of incubation time, temperature, and anticoagulants on platelet aggregation in whole blood.
Thrombosis research 2001;101(3):139-44.
2001: Katsue Suzuki-Inoue; Yoshio Ozaki; M Kainoh; Y Shin; Yi Wu; Yutaka Yatomi; T Ohmori; T Tanaka; Kaneo Satoh; Takashi Morita
Rhodocytin induces platelet aggregation by interacting with glycoprotein Ia/IIa (GPIa/IIa, Integrin alpha 2beta 1). Involvement of GPIa/IIa-associated src and protein tyrosine phosphorylation.
The Journal of biological chemistry 2001;276(2):1643-52.
2001: Minori Nagahama; Shosaku Nomura; Yoshio Ozaki; Chie Yoshimura; Hideo Kagawa; Shirou Fukuhara
Platelet activation markers and soluble adhesion molecules in patients with systemic lupus erythematosus.
Autoimmunity 2001;33(2):85-94.
2001: Minori Nagahama; Hideo Kagawa; Yoshio Ozaki; S Onishi; T Ishida; Shosaku Nomura; Shirou Fukuhara
[Systemic inflammatory response syndrome triggered by necrotizing cholecystitis after treatment of underlying low titer cold agglutinin disease].
[Rinshō ketsueki] The Japanese journal of clinical hematology 2001;42(1):23-9.
2000: Yutaka Yatomi; Tsukasa Ohmori; Ge Rile; F Kazama; H Okamoto; T Sano; Kaneo Satoh; S Kume; G Tigyi; Y Igarashi; Yoshio Ozaki
Sphingosine 1-phosphate as a major bioactive lysophospholipid that is released from platelets and interacts with endothelial cells.
Blood 2000;96(10):3431-8.
2000: R Qi; F Liao; K Inoue; Yutaka Yatomi; K Sato; Yoshio Ozaki
Inhibition by diallyl trisulfide, a garlic component, of intracellular Ca(2+) mobilization without affecting inositol-1,4, 5-trisphosphate (IP(3)) formation in activated platelets.
Biochemical pharmacology 2000;60(10):1475-83.
2000: Yi Wu; Yoshio Ozaki; K Inoue; Kaneo Satoh; T Ohmori; Yutaka Yatomi; K Owadab
Differential activation and redistribution of c-Src and Fyn in platelets, assessed by MoAb specific for C-terminal tyrosine-dephosphorylated c-Src and Fyn.
Biochimica et biophysica acta 2000;1497(1):27-36.
2000: Tsukasa Ohmori; Yutaka Yatomi; K Inoue; Kaneo Satoh; Yoshio Ozaki
Tyrosine dephosphorylation, but not phosphorylation, of p130Cas is dependent on integrin alpha IIb beta 3-mediated aggregation in platelets: implication of p130Cas involvement in pathways unrelated to cytoskeletal reorganization.
Biochemistry 2000;39(19):5797-807.
2000: Kaneo Satoh; Naoki Asazuma; Yutaka Yatomi; Y Fujimura; S Miura; K Titani; Yoshio Ozaki
Activation of protein-tyrosine kinase pathways in human platelets stimulated with the A1 domain of von Willebrand factor.
Platelets 2000;11(3):171-6.
2000: Y Miura; Yutaka Yatomi; Ge Rile; Tsukasa Ohmori; Kaneo Satoh; Yoshio Ozaki
Rho-mediated phosphorylation of focal adhesion kinase and myosin light chain in human endothelial cells stimulated with sphingosine 1-phosphate, a bioactive lysophospholipid released from activated platelets.
Journal of biochemistry 2000;127(5):909-14.
2000: Yoshio Ozaki; Shosaku Nomura; Minori Nagahama; Chie Yoshimura; Hideo Kagawa; Shirou Fukuhara
Vitamin-D receptor genotype and renal disorder in Japanese patients with systemic lupus erythematosus.
Nephron 2000;85(1):86-91.
2000: Tsukasa Ohmori; Yutaka Yatomi; Naoki Asazuma; Kaneo Satoh; Yoshio Ozaki
Involvement of proline-rich tyrosine kinase 2 in platelet activation: tyrosine phosphorylation mostly dependent on alphaIIbbeta3 integrin and protein kinase C, translocation to the cytoskeleton and association with Shc through Grb2.
The Biochemical journal 2000;347(Pt 2):561-9.
2000: Chie Yoshimura; Shosaku Nomura; Minori Nagahama; Yoshio Ozaki; Hideo Kagawa; Shirou Fukuhara
Plasma-soluble Fas (APO-1, CD95) and soluble Fas ligand in immune thrombocytopenic purpura.
European journal of haematology 2000;64(4):219-24.
2000: Minori Nagahama; Shosaku Nomura; K Katsura; Yoshio Ozaki; Chie Yoshimura; Hideo Kagawa; Shirou Fukuhara
Serum levels of soluble CD30 in autologous peripheral blood stem cell transplantation.
Journal of cancer research and clinical oncology 2000;126(2):101-6.
2000: Yoshio Ozaki; R Qi; Kaneo Satoh; Naoki Asazuma; Yutaka Yatomi
Platelet activation mediated through membrane glycoproteins: involvement of tyrosine kinases.
Seminars in thrombosis and hemostasis 2000;26(1):47-51.
1999: L Yang; Yutaka Yatomi; Y Miura; Kaneo Satoh; Yoshio Ozaki
Metabolism and functional effects of sphingolipids in blood cells.
British journal of haematology 1999;107(2):282-93.
1999: R Qi; Yoshio Ozaki; Naoki Asazuma; Kaneo Satoh; Yutaka Yatomi; Che-Leung Law; T Hato; Shosaku Nomura
FcgammaRII tyrosine phosphorylation differs between FcgammaRII cross-linking and platelet-activating anti-platelet monoclonal antibodies.
Biochimica et biophysica acta 1999;1451(2-3):353-63.
1999: Yoshio Ozaki
[Platelet aggregation, platelet release reaction, platelet adhesion].
Nihon rinsho. Japanese journal of clinical medicine 1999;57 Suppl():691-5.
1999: Yoshio Ozaki
[Bleeding time, capillary resistance test].
Nihon rinsho. Japanese journal of clinical medicine 1999;57 Suppl():540-2.
1999: Yoshio Ozaki
[Platelet activation mediated through membrane glycoproteins: involvement of tyrosine kinases].
Rinsho byori. The Japanese journal of clinical pathology 1999;47(9):799-808.
1999: Shosaku Nomura; Hideo Kagawa; Yoshio Ozaki; Minori Nagahama; Chie Yoshimura; Shirou Fukuhara
Relationship between platelet activation and cytokines in systemic inflammatory response syndrome patients with hematological malignancies.
Thrombosis research 1999;95(5):205-13.
1999: L Yang; Yutaka Yatomi; Kaneo Satoh; Y Igarashi; Yoshio Ozaki
Sphingosine 1-phosphate formation and intracellular Ca2+ mobilization in human platelets: evaluation with sphingosine kinase inhibitors.
Journal of biochemistry 1999;126(1):84-9.
1999: N Hisano; Yutaka Yatomi; Kaneo Satoh; S Akimoto; Masako Mitsumata; M A Fujino; Yoshio Ozaki
Induction and suppression of endothelial cell apoptosis by sphingolipids: a possible in vitro model for cell-cell interactions between platelets and endothelial cells.
Blood 1999;93(12):4293-9.
1999: L Yang; Yutaka Yatomi; Kaneo Satoh; Yoshio Ozaki
Inhibitory effects of beraprost on platelet aggregation: comparative study utilizing two methods of aggregometry.
Thrombosis research 1999;94(1):25-32.
1999: Tsukasa Ohmori; Yutaka Yatomi; Naoki Asazuma; Kaneo Satoh; Yoshio Ozaki
Suppression of protein kinase C is associated with inhibition of PYK2 tyrosine phosphorylation and enhancement of PYK2 interaction with Src in thrombin-activated platelets.
Thrombosis research 1999;93(6):291-8.
1999: K Inoue; Yoshio Ozaki; Kaneo Satoh; Yi Wu; Yutaka Yatomi; Y Shin; Takashi Morita
Signal transduction pathways mediated by glycoprotein Ia/IIa in human platelets: comparison with those of glycoprotein VI.
Biochemical and biophysical research communications 1999;256(1):114-20.
1999: H Kagawa; Shosaku Nomura; M Nagahama; Yoshio Ozaki; Shirou Fukuhara
Effect of ticlopidine on platelet-derived microparticles in patients with connective tissue diseases.
Haemostasis 1999;29(5):255-61.
1999: Shosaku Nomura; T Matsuzaki; M Yamaoka; Yoshio Ozaki; Minori Nagahama; Chie Yoshimura; Hideo Kagawa; S Nakayama; Shirou Fukuhara
Genetic analysis of HLA- and HPA-typing in idiopathic (autoimmune) thrombocytopenic purpura patients treated with cepharanthin.
Autoimmunity 1999;30(2):99-105.
1998: Yutaka Yatomi; Yoshio Ozaki; Y Igarashi
[Signal transduction related to sphingosine 1-phosphate].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1998;43(16 Suppl):2510-5.
1998: Yoshio Ozaki; Hideo Kagawa; M Yasuzawa; Chie Yoshimura; Toshiki Shimizu; Shosaku Nomura; H Kitajima; Yuji Kishimoto; Yutaka Komiyama; A Okamura; Shirou Fukuhara
[Anti-fibrinogen antibody detected in a patient with systemic lupus erythematosus and disseminated intravascular coagulation].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1998;39(6):436-41.
1998: Shosaku Nomura; T Matsuzaki; Yoshio Ozaki; M Yamaoka; Chie Yoshimura; K Katsura; G L Xie; Hideo Kagawa; T Ishida; Shirou Fukuhara
Clinical significance of HLA-DRB1*0410 in Japanese patients with idiopathic thrombocytopenic purpura.
Blood 1998;91(10):3616-22.
1998: N Hisano; Yutaka Yatomi; M A Fujino; Y Igarashi; S Kume; Yoshio Ozaki
Quantification of sphingosine derivatives in human platelets: inducible formation of free sphingosine.
Journal of biochemistry 1998;123(2):263-8.
1998: T Matsuzaki; Shosaku Nomura; M Yamaoka; Yoshio Ozaki; Chie Yoshimura; G L Xie; K Katsura; Hideo Kagawa; T Ishida; Shirou Fukuhara
HLA and HPA typing in idiopathic thrombocytopenic purpura patients treated with Kami-kihi-to.
The American journal of Chinese medicine 1998;26(2):191-8.
1997: Naoki Asazuma; Yoshio Ozaki; Kaneo Satoh; Yutaka Yatomi; M Handa; Y Fujimura; S Miura; S Kume
Glycoprotein Ib-von Willebrand factor interactions activate tyrosine kinases in human platelets.
Blood 1997;90(12):4789-98.
1997: Yutaka Yatomi; S Yamamura; F Ruan; S Kume; Yoshio Ozaki; Y Igarashi
N,N-dimethylsphingosine 1-phosphate activates human platelets.
FEBS letters 1997;417(3):341-4.
1997: Yutaka Yatomi; Y Igarashi; L Yang; N Hisano; R Qi; Naoki Asazuma; Kaneo Satoh; Yoshio Ozaki; S Kume
Sphingosine 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum.
Journal of biochemistry 1997;121(5):969-73.
1997: Yoshio Ozaki
[Release of intracellular granule contents in platelets].
Nihon rinsho. Japanese journal of clinical medicine 1997;55 Suppl 1():109-12.
1997: M Yanabu; Yoshio Ozaki; Shosaku Nomura; T Miyake; Y Miyazaki; Hideo Kagawa; Y Yamanaka; Naoki Asazuma; Kaneo Satoh; S Kume; Y Komiyama; Shirou Fukuhara
Tyrosine phosphorylation and p72syk activation by an anti-glycoprotein Ib monoclonal antibody.
Blood 1997;89(5):1590-8.
1997: Yutaka Yatomi; Yoshio Ozaki; Kaneo Satoh; S Kume; F Ruan; Y Igarashi
N,N-dimethylsphingosine phosphorylation in human platelets.
Biochemical and biophysical research communications 1997;231(3):848-51.
1996: R Qi; Yoshio Ozaki; K Kuroda; Naoki Asazuma; Yutaka Yatomi; Kaneo Satoh; S Nomura; S Kume
Differential activation of human platelets induced by Fc gamma receptor II cross-linking and by anti-CD9 monoclonal antibody.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(12):5638-45.
1996: L Yang; Yutaka Yatomi; N Hisano; R Qi; Naoki Asazuma; Kaneo Satoh; Y Igarashi; Yoshio Ozaki; S Kume
Activation of protein-tyrosine kinase Syk in human platelets stimulated with lysophosphatidic acid or sphingosine 1-phosphate.
Biochemical and biophysical research communications 1996;229(2):440-4.
1996: Kaneo Satoh; Yoshio Ozaki; Naoki Asazuma; Yutaka Yatomi; Q Ruomei; K Kuroda; L Yang; S Kume
Differential mobilization of tyrosine kinases in human platelets stimulated with thrombin or thrombin receptor agonist peptide.
Biochemical and biophysical research communications 1996;225(3):1084-9.
1996: R Qi; Yoshio Ozaki; Kaneo Satoh; L B Yang; Naoki Asazuma; Yutaka Yatomi; S Kume
Intracellular levels of cyclic AMP and cyclic GMP differentially modify platelet aggregate size in human platelets activated with epinephrine or ADP.
Journal of cardiovascular pharmacology 1996;28(2):215-22.
1996: Naoki Asazuma; Yutaka Yatomi; Yoshio Ozaki; R Qi; K Kuroda; Kaneo Satoh; S Kume
Protein-tyrosine phosphorylation and p72syk activation in human platelets stimulated with collagen is dependent upon glycoprotein Ia/IIa and actin polymerization.
Thrombosis and haemostasis 1996;75(4):648-54.
1996: Kaneo Satoh; Yoshio Ozaki; R Qi; L Yang; Naoki Asazuma; Yutaka Yatomi; S Kume
Factors that affect the size of platelet aggregates in epinephrine-induced activation: a study using the particle counting method based upon light scattering.
Thrombosis research 1996;81(5):515-23.
1996: R Qi; Yoshio Ozaki; Kaneo Satoh; K Kurota; Naoki Asazuma; Yutaka Yatomi; S Kume
Quantitative measurement of various 5-HT receptor antagonists on platelet activation induced by serotonin.
Thrombosis research 1996;81(1):43-54.
1995: K Kuroda; Yoshio Ozaki; R Qi; Naoki Asazuma; Yutaka Yatomi; Kaneo Satoh; S Nomura; M Suzuki; S Kume
Fc gamma II receptor-mediated platelet activation induced by anti-CD9 monoclonal antibody opens Ca2+ channels which are distinct from those associated with Ca2+ store depletion.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(9):4427-36.
1995: Yutaka Yatomi; Yoshio Ozaki; S Kume
Phosphoinositide metabolism triggered by wheat germ agglutinin in human platelets.
International journal of hematology 1995;62(3):163-73.
1995: Yoshio Ozaki; Kaneo Satoh; K Kuroda; R Qi; Yutaka Yatomi; S Yanagi; K Sada; H Yamamura; M Yanabu; S Nomura
Anti-CD9 monoclonal antibody activates p72syk in human platelets.
The Journal of biological chemistry 1995;270(25):15119-24.
1995: R Qi; Yoshio Ozaki; Kaneo Satoh; K Kurota; Naoki Asazuma; Yutaka Yatomi; S Kume
Sulphonylurea agents inhibit platelet aggregation and [Ca2+]i elevation induced by arachidonic acid.
Biochemical pharmacology 1995;49(12):1735-9.
1995: Kaneo Satoh; Yoshio Ozaki; S Kume
[Detection of platelet aggregates using light scattering].
Rinsho byori. The Japanese journal of clinical pathology 1995;43(5):426-31.
1995: Yoshio Ozaki; Kaneo Satoh; Yutaka Yatomi; S Miura; Y Fujimura; S Kume
Protein tyrosine phosphorylation in human platelets induced by interaction between glycoprotein Ib and von Willebrand factor.
Biochimica et biophysica acta 1995;1243(3):482-8.
1994: Kaneo Satoh; Yoshio Ozaki; Yutaka Yatomi; S Kume
Effects of sulfonylurea agents on platelet arachidonic acid metabolism; study on platelet homogenates.
Biochemical pharmacology 1994;48(5):1053-5.
1994: Yutaka Yatomi; Yoshio Ozaki; Kaneo Satoh; S Kume
Synthesis of phosphatidylinositol 3,4-bisphosphate is regulated by protein-tyrosine phosphorylation but the p85 alpha subunit of phosphatidylinositol 3-kinase may not be a target for tyrosine kinases in thrombin-stimulated human platelets.
Biochimica et biophysica acta 1994;1212(3):337-44.
1994: Y Koike; Yoshio Ozaki; R Qi; Kaneo Satoh; K Kurota; Yutaka Yatomi; S Kume
Phosphatase inhibitors suppress Ca2+ influx induced by receptor-mediated intracellular Ca2+ store depletion in human platelets.
Cell calcium 1994;15(5):381-90.
1994: Yutaka Yatomi; M Higashihara; K Kurokawa; Yoshio Ozaki; S Kume
Effects of the prior activation of protein kinase C on human platelet activation induced by thrombin.
International journal of hematology 1994;59(3):201-9.
1993: Yoshio Ozaki; Yutaka Yatomi; Y Jinnai; S Kume
Effects of genistein, a tyrosine kinase inhibitor, on platelet functions. Genistein attenuates thrombin-induced Ca2+ mobilization in human platelets by affecting polyphosphoinositide turnover.
Biochemical pharmacology 1993;46(3):395-403.
1993: Yutaka Yatomi; Yoshio Ozaki; Kaneo Satoh; S Kume
Anti-CD9 monoclonal antibody elicits staurosporine inhibitable phosphatidylinositol 4,5-bisphosphate hydrolysis, phosphatidylinositol 3,4-bisphosphate synthesis, and protein-tyrosine phosphorylation in human platelets.
FEBS letters 1993;322(3):285-90.
1993: Yoshio Ozaki; Y Jinnai; Yutaka Yatomi; M Tawata; T Onaya; S Kume
Effects of dilazep on platelet functions and volume change in patients with diabetes mellitus.
Arzneimittel-Forschung 1993;43(5):536-9.
1993: Yoshio Ozaki; Y Jinnai; Yutaka Yatomi; S Kume
Protein kinase C inhibitors suppress disc-sphere changes of human platelets, as assessed with the shape-change parameter.
European journal of pharmacology 1993;235(2-3):255-65.
1993: Yoshio Ozaki; Kaneo Satoh; Yutaka Yatomi; S Kume
Low concentrations of sodium fluoride inhibit Ca2+ influx induced by receptor-mediated platelet activation.
Biochimica et biophysica acta 1993;1147(1):27-34.
1993: Yutaka Yatomi; Yoshio Ozaki; Y Koike; Kaneo Satoh; S Kume
Wheat germ agglutinin-induced intracellular calcium mobilization in human platelets: suppression by staurosporine and resistance to cyclic AMP inhibition.
Biochemical and biophysical research communications 1993;191(2):453-8.
1992: Yoshio Ozaki
[Effect of pH on blood cells].
Nihon rinsho. Japanese journal of clinical medicine 1992;50(9):2112-8.
1992: Yoshio Ozaki; Yutaka Yatomi; S Kume
Effects of oral hypoglycaemic agents on platelet functions.
Biochemical pharmacology 1992;44(4):687-91.
1992: Yutaka Yatomi; Yoshio Ozaki; S Kume
Synthesis of phosphatidylinositol 3,4-bisphosphate but not phosphatidylinositol 3,4,5-trisphosphate is closely correlated with protein-tyrosine phosphorylation in thrombin-activated human platelets.
Biochemical and biophysical research communications 1992;186(3):1480-6.
1992: Yoshio Ozaki; Yutaka Yatomi; S Wakasugi; Y Shirasawa; H Saito; S Kume
Thrombin-induced calcium oscillation in human platelets and MEG-01, a megakaryoblastic leukemia cell line.
Biochemical and biophysical research communications 1992;183(2):864-71.
1992: Yoshio Ozaki; Y Yatomi; S Kume
[Evaluation of platelet intracellular calcium ion concentrations with flow cytometry].
Rinsho byori. The Japanese journal of clinical pathology 1992;40(3):282-6.
1992: Masato Tawata; K Aida; T Noguchi; Yoshio Ozaki; S Kume; H Sasaki; M Chin; Toshimasa Onaya
Anti-platelet action of isoliquiritigenin, an aldose reductase inhibitor in licorice.
European journal of pharmacology 1992;212(1):87-92.
1992: Yoshio Ozaki
[Effect of protein kinase C activation on platelet Na+/H+ exchanger].
Nihon rinsho. Japanese journal of clinical medicine 1992;50(2):254-8.
1992: Yoshio Ozaki; Yutaka Yatomi; S Kume
Evaluation of platelet calcium ion mobilization by the use of various divalent ions.
Cell calcium 1992;13(1):19-27.
1991: Yoshio Ozaki; Y Jinnai; Yutaka Yatomi; S Kume
Role of sodium ion gradient in facilitating extracellular calcium influx.
Thrombosis research 1991;64(2):179-90.
1991: Yoshio Ozaki; Y Matsumoto; Yutaka Yatomi; M Higashihara; S Kume
Two-step mobilization of arachidonic acid in platelet activation induced by low concentrations of TP 82, a monoclonal antibody against CD9 antigen.
European journal of biochemistry / FEBS 1991;199(2):347-54.
1990: Yoshio Ozaki; Y Matsumoto; Yutaka Yatomi; M Higashihara; T Kariya; S Kume
Effects of various inhibitors on platelet activation induced by TP 82, a CD 9 monoclonal antibody.
Biochemical pharmacology 1990;40(7):1583-8.
1990: Y Matsumoto; Yoshio Ozaki; T Kariya; S Kume
Potentiating effects of endothelin on platelet activation induced by epinephrine and ADP.
Biochemical pharmacology 1990;40(4):909-11.
1990: Yoshio Ozaki; Y Matsumoto; Yutaka Yatomi; M Higashihara; S Kume
Modification of Na+/H+ exchanger in human platelets by 1,2-dioctanoylglycerol, a protein kinase C activator.
Thrombosis and haemostasis 1990;64(1):165-71.
1990: Yoshio Ozaki; Y Matsumoto; Yutaka Yatomi; M Higashihara; T Kariya; S Kume
Mastoparan, a wasp venom, activates platelets via pertussis toxin-sensitive GTP-binding proteins.
Biochemical and biophysical research communications 1990;170(2):779-85.
1990: Yoshio Ozaki; Y Matsumoto; Yutaka Yatomi; M Higashihara; T Kariya; S Kume
Ionomycin, a Ca++ ionophore, increases platelet volume independently of the Na+/H+ exchanger.
Thrombosis research 1990;57(1):87-95.
1989: Yoshio Ozaki; Y Matsumoto; Yutaka Yatomi; M Higashihara; T Kariya; K Shoji
Effects of five anion channel blockers on thrombin- and ionomycin-activated platelet functions.
Biochemical pharmacology 1989;38(13):2147-52.