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Wolfgang Berdel

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Sandra Heesch; Michael Heuser; Dieter Hoelzer; Wolf-Karsten Hofmann; Martin Neumann; Cornelia Schlee; Stefan Schwartz; Eckhard Thiel; Clemens-Martin Wendtner; Isabelle Bartram; Wolfgang E Berdel; Thomas Burmeister; Arnold Ganser; Nicola Gökbuget; Matthias Hänel; Claudia D Baldus
Acute leukemias of ambiguous lineage in adults: molecular and clinical characterization.
Christian Schwöppe; Jörg Stypmann; Caroline Zerbst; Alena Dreiling; Max Fröhlich; Carsten Höltke; Richard Holtmeier; Torsten Kessler; Simone Koenig; Rüdiger Liersch; Martin Lücke; Rolf M Mesters; Carsten Müller-Tidow; Laura Overkamp; Christoph Schliemann; Wolfgang E Berdel
Anticancer therapy by tumor vessel infarction with polyethylene glycol conjugated retargeted tissue factor.
Till Schoofs; Isabell Schulze; Monika Stoll; Anika Witten; Christian Rohde; Frank Rosenbauer; Peter Schlenke; Shuchi Agrawal-Singh; Wolfgang E Berdel; Thomas Büchner; Nikolaj Dietrich; Martin Dugas; Stefanie Göllner; Klaus Hansen; Katja Hebestreit; Wolf-Karsten Hofmann; Hans-Ulrich Klein; Eva Lengfelder; Mads Lerdrup; Carsten Müller-Tidow
DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding.

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2013: Sandra Heesch; Michael Heuser; Dieter Hoelzer; Wolf-Karsten Hofmann; Martin Neumann; Cornelia Schlee; Stefan Schwartz; Eckhard Thiel; Clemens-Martin Wendtner; Isabelle Bartram; Wolfgang E Berdel; Thomas Burmeister; Arnold Ganser; Nicola Gökbuget; Matthias Hänel; Claudia D Baldus
Acute leukemias of ambiguous lineage in adults: molecular and clinical characterization.
Annals of hematology 2013;92(6):747-58.
2013: Christian Schwöppe; Jörg Stypmann; Caroline Zerbst; Alena Dreiling; Max Fröhlich; Carsten Höltke; Richard Holtmeier; Torsten Kessler; Simone Koenig; Rüdiger Liersch; Martin Lücke; Rolf M Mesters; Carsten Müller-Tidow; Laura Overkamp; Christoph Schliemann; Wolfgang E Berdel
Anticancer therapy by tumor vessel infarction with polyethylene glycol conjugated retargeted tissue factor.
Journal of medicinal chemistry 2013;56(6):2337-47.
2013: Till Schoofs; Isabell Schulze; Monika Stoll; Anika Witten; Christian Rohde; Frank Rosenbauer; Peter Schlenke; Shuchi Agrawal-Singh; Wolfgang E Berdel; Thomas Büchner; Nikolaj Dietrich; Martin Dugas; Stefanie Göllner; Klaus Hansen; Katja Hebestreit; Wolf-Karsten Hofmann; Hans-Ulrich Klein; Eva Lengfelder; Mads Lerdrup; Carsten Müller-Tidow
DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding.
Blood 2013;121(1):178-87.
2013: Eva Lengfelder; Carsten Müller-Tidow; Cristina Sauerland; Stephanie Schneider; Susanne Schnittger; Beate Schultheis; Hubert Serve; Karsten Spiekermann; Bernhard Wörmann; Carlo Aul; Wolfgang E Berdel; Jan Braess; Thomas Büchner; Philipp Erben; Claudia Haferlach; Torsten Haferlach; Benjamin Hanfstein; Rüdiger Hehlmann; Achim Heinecke; Wolfgang Hiddemann; Wolf-Karsten Hofmann; Heinz A Horst; Karl-Anton Kreuzer; Utz Krug
Outcome of elderly patients with acute promyelocytic leukemia: results of the German Acute Myeloid Leukemia Cooperative Group.
Annals of hematology 2013;92(1):41-52.
2012: Ruediger Liersch; Rolf M Mesters; Wolfgang E Berdel; Satoshi Hirakawa; Michael Detmar
Induced lymphatic sinus hyperplasia in sentinel lymph nodes by VEGF-C as the earliest premetastatic indicator.
International journal of oncology 2012;41(6):2073-8.
2012: Philipp A Greif; Tobias Herold; Wolfgang Hiddemann; Purvi M Kakadia; Nikola P Konstandin; Bianka Ksienzyk; Klaus Metzeler; Zlatana Pasalic; Maria Cristina Sauerland; Friederike Schneider; Stephanie Schneider; Karsten Spiekermann; Bernhard J Woermann; Wolfgang E Berdel; Jan Braess; Thomas Büchner; Annika Dufour; Stefan K Bohlander
RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes.
Haematologica 2012;97(12):1909-15.
2012: Peter Razlaf; Holger Reinecke; Matthias Stelljes; Johannes Waltenberger; Rainer Wiewrodt; Wolfgang E Berdel; Torsten Kessler; Michael Mohr; Dirk Pabst; Pia Lebiedz
Non-invasive ventilation in immunosuppressed patients with pneumonia and extrapulmonary sepsis.
Respiratory medicine 2012;106(11):1509-16.
2012: Thomas Büchner; Hartmut Döhner; Konstanze Döhner; Gerhard Ehninger; Arnold Ganser; Joerg Hasford; Rüdiger Hehlmann; Gerhard Heil; Achim Heinecke; Wolfgang Hiddemann; Dieter Hoelzer; Verena S Hoffmann; Rainer Krahl; Michael Kramer; Jürgen Krauter; Utz Krug; Dietger W Niederwieser; Maria Cristina Sauerland; Markus Schaich; Richard F Schlenk; Sebastian Scholl; Daniela Späth; Wolfgang E Berdel; Markus Pfirrmann
Acute Myeloid Leukemia (AML): different treatment strategies versus a common standard arm--combined prospective analysis by the German AML Intergroup.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(29):3604-10.
2012: Martin Bornhäuser; Stefanie Buchholz; Andreas Burchert; Peter Dreger; Gerhard Ehninger; Herrmann Einsele; Ute Hegenbart; Wolfgang Hiddemann; Ernst Holler; Michael G Kiehl; Joachim Kienast; Nicolaus Kröger; Andreas Neubauer; Kerstin Schäfer-Eckart; Johannes Schetelig; Christoph Schmid; Rainer Schwerdtfeger; Michael Stadler; Herrad Baurmann; Dietrich W Beelen; Wolfgang E Berdel; Rudolf Trenschel; Matthias Stelljes
Reduced-intensity conditioning versus standard conditioning before allogeneic haemopoietic cell transplantation in patients with acute myeloid leukaemia in first complete remission: a prospective, open-label randomised phase 3 trial.
The lancet oncology 2012;13(10):1035-44.
2012: M Mohr; Carsten Müller-Tidow; Gerald Pühse; Michael Semik; Tilmann Spieker; K Wiebe; C Hamisch; I Hartig; Lothar Hertle; Torsten Kessler; Sabine Kliesch; U Krug; Rüdiger Liersch; Rolf M Mesters; Wolfgang E Berdel
High-dose chemotherapy with autologous PBSC transplantation for poor prognosis germ cell tumors: a retrospective monocenter analysis of 44 cases.
Bone marrow transplantation 2012;47(10):1321-5.
2012: Pierre Kyme; Kunik Lee; Wolfgang E Berdel; Adrian F Gombart; W David Hardy; H Phillip Koeffler; Utz O Krug; Carsten Müller-Tidow; Kenichi Shimada; Gabriela B Thoennissen; Nils H Thoennissen; Ching Wen Tseng; Andrea J Wolf; George Y Liu
C/EBPε mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice.
The Journal of clinical investigation 2012;122(9):3316-29.
2012: Gabriela B Thoennissen; Nils Thoennissen; Fleur Fritz; Andreas Hilbig; Andrea Kerkhoff; Steffen Koschmieder; Martin Kropff; Utz Krug; Rüdiger Liersch; Rolf M Mesters; Carsten Müller-Tidow; Wolfgang E Berdel
POEMS syndrome treated with melphalan high-dose therapy and autologous blood stem cell transplantation: a single-institution experience.
Annals of hematology 2012;91(9):1419-25.
2012: Agnieszka Korfel; M Leithäuser; Peter Martus; Hans-Günther Mergenthaler; M Rauch; A Roeth; P Roth; J Schubert; Eckhard Thiel; Michael Weller; Wolfgang E Berdel; Josef Birkmann; T Birnbaum; T Fischer; Bernd Hertenstein; M Hummel; Thomas Hundsberger; H Kirchen; H A Klasen; Lars Fischer
Prognostic impact of meningeal dissemination in primary CNS lymphoma (PCNSL): experience from the G-PCNSL-SG1 trial.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2012;23(9):2374-80.
2012: Pavankumar N G Reddy; Bülent Sargin; Hubert Serve; Stefan Stein; Wolfgang E Berdel; Christian Brandts; Chunaram Choudhary; Manuel Grez; Carsten Müller-Tidow
SOCS1 cooperates with FLT3-ITD in the development of myeloproliferative disease by promoting the escape from external cytokine control.
Blood 2012;120(8):1691-702.
2012: Philipp A Greif; Andreas Hauser; Tobias Herold; Wolfgang Hiddemann; Karl-Peter Hopfner; Eva Hoster; Purvi M Kakadia; Nikola P Konstandin; Stefan Krebs; Bianka Ksienzyk; Maria Cristina Sauerland; Friederike Schneider; Stephanie Schneider; Karsten Spiekermann; Martin Stanulla; Jutta Sturm; Belay Tizazu; Bernhard J Woermann; Marjan Yaghmaie; Evelyn Zellmeier; Tobias Benthaus; Wolfgang E Berdel; Helmut Blum; Jan Braess; Thomas Büchner; Petra Dörge; Annika Dufour; Alexander Graf; Stefan K Bohlander
GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia.
Blood 2012;120(2):395-403.
2012: Annika Dufour; Wolfgang Hiddemann; Eva Hoster; Purvi M Kakadia; Bianka Ksienzyk; Maria Cristina Sauerland; Friederike Schneider; Stephanie Schneider; Karsten Spiekermann; Marion Subklewe; Bernhard Wörmann; Tobias Benthaus; Wolfgang E Berdel; Stefan K Bohlander; Jan Braess; Thomas Büchner
Monoallelic CEBPA mutations in normal karyotype acute myeloid leukemia: independent favorable prognostic factor within NPM1 mutated patients.
Annals of hematology 2012;91(7):1051-63.
2012: Christoph Röllig; Eberhard Schleyer; Hubert Serve; Shabnam Shaid; Carsten Müller-Tidow; Karl-Heinz Pflüger; Barbara Ritter; Wolfgang E Berdel; Christian Brandts; Gerhard Ehninger; Martina Haibach; Marcus Hentrich; Christian Junghanß; Alwin Krämer; Michael Kramer; Stefan W Krause
Survey and analysis of the efficacy and prescription pattern of sorafenib in patients with acute myeloid leukemia.
Leukemia & lymphoma 2012;53(6):1062-7.
2012: Rüdiger Liersch; Bob Löwenberg; Carsten Müller-Tidow; Christoph Schliemann; Christian Schwöppe; Iris Appelmann; Michael Bayer; Wolfgang E Berdel; Christoph Biermann; Thomas Büchner; Joachim Gerss; Wolfgang Hiddemann; Torsten Kessler; Rolf M Mesters
Osteopontin is a prognostic factor for survival of acute myeloid leukemia patients.
Blood 2012;119(22):5215-20.
2012: Friederike Schneider; Stephanie Schneider; Michael Unterhalt; Bernhard J Wörmann; Evelyn Zellmeier; Tobias Benthaus; Wolfgang E Berdel; Stefan K Bohlander; Jan Braess; Thomas Büchner; Christian Buske; Annika Dufour; Michaela Feuring-Buske; Achim Heinecke; Wolfgang Hiddemann; Eva Hoster; Purvi M Kakadia; Gudrun Mellert; Maria Cristina Sauerland; Karsten Spiekermann
The FLT3ITD mRNA level has a high prognostic impact in NPM1 mutated, but not in NPM1 unmutated, AML with a normal karyotype.
Blood 2012;119(19):4383-6.
2012: M Schemionek; Tilmann Spieker; A Trumpp; Carsten Müller-Tidow; Wolfgang E Berdel; C Elling; Marieke A G Essers; L Kerstiens; Steffen Koschmieder
Leukemic spleen cells are more potent than bone marrow-derived cells in a transgenic mouse model of CML.
Leukemia 2012;26(5):1030-7.
2012: U Brunnberg; T Büchner; U Dührsen; H A Dürk; Gerhard Ehninger; T Kessler; M Kosch; Steffen Koschmieder; U Krug; Rolf M Mesters; M Mohr; C Müller-Tidow; R Noppeney; Maria Cristina Sauerland; C Schulz; H Serve; Wolfgang E Berdel
Induction therapy of AML with ara-C plus daunorubicin versus ara-C plus gemtuzumab ozogamicin: a randomized phase II trial in elderly patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2012;23(4):990-6.
2012: Shuchi Agrawal-Singh; Nicole Bäumer; Anke Becker; Wolfgang E Berdel; Thomas Büchner; Martin Dugas; Gerhard Ehninger; Klaus Hansen; Antje Hascher; Fabienne Isken; Hans-Ulrich Klein; Gabriele Koehler; Steffen Koschmieder; Utz Krug; Michael McClelland; Peter Schlenke; Hubert Serve; Shailendra Vikram Singh; Christian Thiede; Nils Thoennissen; Yipeng Wang; Dae-Yeul Yu; Konstantin Agelopoulos; Carsten Müller-Tidow
Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene.
Blood 2012;119(10):2346-57.
2012: Christian Brandts; Georg Gosheger; Jendrik Hardes; Achim Heinecke; Christiane Schulz; Hubert Serve; Björn Steffen; Normann Willich; Winfried Winkelmann; Wolfgang E Berdel; Michael Thomas
Adjuvant therapy for resectable high-risk soft tissue sarcoma: feasibility and efficacy of a sandwich chemoradiotherapy strategy.
Cancer chemotherapy and pharmacology 2012;69(3):613-20.
2012: Ruth von Scheven; Wolfgang E Berdel; Pia Lebiedz; Tilmann Spieker; Andreas Uekoetter; Torsten Kessler
Fulminant invasive pulmonary mucormycosis with Rhizopus oryzae in a patient with severe aplastic anaemia and common variable immunodeficiency.
Mycoses 2012;55(2):e32-5.
2012: C I-U Chen; J Gerss; Heribert Juergens; L Kerstiens; Steffen Koschmieder; P P Lee; H T Maecker; Sibylle Pscherer; Bianca Altvater; Wolfgang E Berdel; M Schemionek; Claudia Rossig
NK cells are dysfunctional in human chronic myelogenous leukemia before and on imatinib treatment and in BCR-ABL-positive mice.
Leukemia 2012;26(3):465-74.
2012: Tobias Goerge; Rolf M Mesters; Guenther Schellong; Wolfgang E Berdel
Mimicry of hydroxyurea-induced leg ulcer by distal vena saphena parva insufficiency.
Annals of hematology 2012;91(3):471-2.
2012: Utz Krug; Wolfgang E Berdel; Christian Brandts; Thomas Büchner; Gesine Bug; Ulrich Dührsen; Gerhard Ehninger; Joachim Gerss; Anja Koschmieder; Steffen Koschmieder; Richard Noppeney; Christoph Röllig; Markus Schaich; Daniela Schwammbach; Hubert Serve; Björn Steffen; Matthias Stelljes; Christian Thiede; Nicola Tidow; Carsten Müller-Tidow
Feasibility of azacitidine added to standard chemotherapy in older patients with acute myeloid leukemia--a randomised SAL pilot study.
PloS one 2012;7(12):e52695.
2012: Etmar Bulk; Antje Hascher; Ludger Hillejan; Steffen Koschmieder; Utz Krug; Alessandro Marra; Albrecht Schwab; Bernd Timmermann; Karsten Wiebe; Rainer Wiewrodt; Jun Yu; Wolfgang E Berdel; Carsten Müller-Tidow
Mutations of the EPHB6 receptor tyrosine kinase induce a pro-metastatic phenotype in non-small cell lung cancer.
PloS one 2012;7(12):e44591.
2011: Utz Krug; Wolfgang E Berdel; Thomas Büchner; Carsten Müller-Tidow
The treatment of elderly patients with acute myeloid leukemia.
Deutsches Ärzteblatt international 2011;108(51-52):863-70.
2011: Lars Henning Schmidt; Tilmann Spieker; Karsten Wiebe; Rainer Wiewrodt; Danielle Wittmer; Sonja Schäffers; Wolfgang E Berdel; Etmar Bulk; Antje Hascher; Ludger Hillejan; Julia Humberg; Dominik Jungen; Steffen Koschmieder; Alessandro Marra; Carsten Muller-Tidow
The long noncoding MALAT-1 RNA indicates a poor prognosis in non-small cell lung cancer and induces migration and tumor growth.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2011;6(12):1984-92.
2011: Michele Pohlen; Iris Appelmann; Hans U Gerth; Torsten Kessler; Steffen Koschmieder; Rüdiger Liersch; Rolf M Mesters; Carsten Müller-Tidow; Wolfgang E Berdel
Efficacy and toxicity of a rituximab and methotrexate based regimen (GMALL B-ALL/NHL 2002 protocol) in Burkitt's and primary mediastinal large B-cell lymphoma.
American journal of hematology 2011;86(12):E61-4.
2011: Claudia Rossig; Heribert Juergens; Wolfgang E Berdel
New targets and targeted drugs for the treatment of cancer: an outlook to pediatric oncology.
Pediatric hematology and oncology 2011;28(7):539-55.
2011: Andreas N Schüring; Johannes Wessling; Verena Nordhoff; Nicole Schulte; Wolfgang E Berdel; Ludwig Kiesel; Sabine Kliesch; Steffen Koschmieder
Spontaneous conception and live birth after gonadotoxic chemotherapy for an aggressive bilateral ovarian Burkitt's lymphoma.
European journal of obstetrics, gynecology, and reproductive biology 2011;158(2):362-4.
2011: Nicole Bäumer; Sebastian Bäumer; Wolfgang E Berdel; Sven Diederichs; Gabriele Köhler; Steffen Koschmieder; Lisa Lohmeyer; Hubert Serve; Boris V Skryabin; Lara Tickenbrock; Petra Tschanter; Feng Zhang; Shuchi Agrawal-Singh; Carsten Müller-Tidow
Inhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signaling.
The Journal of biological chemistry 2011;286(32):28210-22.
2011: Geoffrey von Maltzahn; Wolfgang E Berdel; Kevin Y Lin; Rolf Mesters; Ji-Ho Park; Erkki Ruoslahti; Michael J Sailor; Christian Schwöppe; Neetu Singh; Sangeeta N Bhatia
Nanoparticles that communicate in vivo to amplify tumour targeting.
Nature materials 2011;10(7):545-52.
2011: Matthias Stelljes; Renate Arnold; Dietrich W Beelen; Wolfgang E Berdel; Bjorna Berning; Jan Braess; Thomas Büchner; Achim Heinecke; Wolfgang Hiddemann; Ernst Holler; Joachim Kienast; Hans J Kolb; Carsten Müller-Tidow; Maria Cristina Sauerland; Rainer Schwerdtfeger; Hubert Serve; Gerda Silling; Karsten Spiekermann
Allogeneic transplantation as post-remission therapy for cytogenetically high-risk acute myeloid leukemia: landmark analysis from a single prospective multicenter trial.
Haematologica 2011;96(7):972-9.
2011: Matthias Stelljes; Carsten Müller-Tidow; Claudia Rossig; Richard F Schlenk; Gerda Silling; Wolfgang E Berdel; Andrea Corbacioglu; Hartmut Döhner; Konstanze Döhner; Karoline Ehlert; M C Frühwald; H Juergens; Joachim Kienast; Steffen Koschmieder
Allogeneic stem cell transplant to eliminate germline mutations in the gene for CCAAT-enhancer-binding protein α from hematopoietic cells in a family with AML.
Leukemia 2011;25(7):1209-10.
2011: Lara Tickenbrock; Hans-Ulrich Klein; Cristina Trento; Antje Hascher; Stefanie Göllner; Nicole Bäumer; Robert Kuss; Shuchi Agrawal; Gesine Bug; Hubert Serve; Christian Thiede; Gerhard Ehninger; Udo Zur Stadt; Michael McClelland; Yipeng Wang; Anke Becker; Steffen Koschmieder; Wolfgang E Berdel; Martin Dugas; Carsten Müller-Tidow
Increased HDAC1 deposition at hematopoietic promoters in AML and its association with patient survival.
Leukemia research 2011;35(5):620-5.
2011: Björn Steffen; Markus Knop; Ulla Bergholz; Olesya Vakhrusheva; Miriam Rode; Gabriele Köhler; Marcel-Philipp Henrichs; Etmar Bulk; Sina Hehn; Martin Stehling; Martin Dugas; Nicole Bäumer; Petra Tschanter; Christian Brandts; Steffen Koschmieder; Wolfgang E Berdel; Hubert Serve; Carol Stocking; Carsten Müller-Tidow
AML1/ETO induces self-renewal in hematopoietic progenitor cells via the Groucho-related amino-terminal AES protein.
Blood 2011;117(16):4328-37.
2011: Christian Elling; Philipp Erben; Christoph Walz; Marie Frickenhaus; Mirle Schemionek; Martin Stehling; Hubert Serve; Nicholas C P Cross; Andreas Hochhaus; Wolf-Karsten Hofmann; Wolfgang E Berdel; Carsten Müller-Tidow; Andreas Reiter; Steffen Koschmieder
Novel imatinib-sensitive PDGFRA-activating point mutations in hypereosinophilic syndrome induce growth factor independence and leukemia-like disease.
Blood 2011;117(10):2935-43.
2011: Feng Zhang; Tao Zhang; Miriam Rode; Nicole Bäumer; Wolfgang E Berdel; Ping Ji; Carsten Müller-Tidow
The inhibitor of growth protein 5 (ING5) depends on INCA1 as a co-factor for its antiproliferative effects.
PloS one 2011;6(7):e21505.
2011: Iris Appelmann; Christoph Biermann; Inken Hartig; Wolfgang E Berdel; Rolf M Mesters
Acquired haemophilia in a patient with discoid lupus.
Annals of hematology 2011;90(1):119-20.
2010: Utz Krug; Christoph Röllig; Anja Koschmieder; Achim Heinecke; Maria Cristina Sauerland; Markus Schaich; Christian Thiede; Michael Kramer; Jan Braess; Karsten Spiekermann; Torsten Haferlach; Claudia Haferlach; Steffen Koschmieder; Christian Rohde; Hubert Serve; Bernhard Wörmann; Wolfgang Hiddemann; Gerhard Ehninger; Wolfgang E Berdel; Thomas Büchner; Carsten Müller-Tidow
Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes.
Lancet 2010;376(9757):2000-8.
2010: Johannes Dreischalück; Christian Schwöppe; Tilmann Spieker; Torsten Kessler; Klaus Tiemann; Ruediger Liersch; Christoph Schliemann; Michael Kreuter; Astrid Kolkmeyer; Heike Hintelmann; Rolf M Mesters; Wolfgang E Berdel
Vascular infarction by subcutaneous application of tissue factor targeted to tumor vessels with NGR-peptides: activity and toxicity profile.
International journal of oncology 2010;37(6):1389-97.
2010: Carsten Müller-Tidow; Hans-Ulrich Klein; Antje Hascher; Fabienne Isken; Lara Tickenbrock; Nils Thoennissen; Shuchi Agrawal-Singh; Petra Tschanter; Christine Disselhoff; Yipeng Wang; Anke Becker; Christian Thiede; Gerhard Ehninger; Udo zur Stadt; Steffen Koschmieder; Matthias Seidl; Frank U Müller; Wilhelm Schmitz; Peter Schlenke; Michael McClelland; Wolfgang E Berdel; Martin Dugas; Hubert Serve
Profiling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia.
Blood 2010;116(18):3564-71.
2010: Claudia Hömme; Utz Krug; N Tidow; Bernd Schulte; Gabriele Kühler; Hubert Serve; Horst Bürger; Wolfgang E Berdel; Martin Dugas; Achim Heinecke; Thomas Büchner; Steffen Koschmieder; Carsten Müller-Tidow
Low SMC1A protein expression predicts poor survival in acute myeloid leukemia.
Oncology reports 2010;24(1):47-56.
2010: Shuchi Agrawal-Singh; Steffen Koschmieder; Sandra Gelsing; Carol Stocking; Martin Stehling; Christian Thiede; Nils Thoennissen; Gabriele Köhler; Peter J M Valk; Ruud Delwel; Ken Mills; Nicole Bäumer; Lara Tickenbrock; Klaus Hansen; Wolfgang E Berdel; Carsten Müller-Tidow; Hubert Serve
Pim2 cooperates with PML-RARalpha to induce acute myeloid leukemia in a bone marrow transplantation model.
Blood 2010;115(22):4507-16.
2010: Cord Rehmsmeier; Torsten Kessler; Steffen Koschmieder; Matthias Ross; Matthias Weckesser; Johannes Wessling; Gabriele Koehler; Wolfgang E Berdel
Mixed response in interim positron emission tomography/computed tomography leads to detection of a gastrointestinal stromal tumor in a patient with mediastinal diffuse large B-cell lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(14):e215-7.
2010: Jun Yu; Etmar Bulk; Ping Ji; Antje Hascher; Moying Tang; Ralf Metzger; Alessandro Marra; Hubert Serve; Wolfgang E Berdel; Rainer Wiewroth; Steffen Koschmieder; Carsten Müller-Tidow
The EPHB6 receptor tyrosine kinase is a metastasis suppressor that is frequently silenced by promoter DNA hypermethylation in non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(8):2275-83.
2010: Christian Schwöppe; Torsten Kessler; Thorsten Persigehl; Ruediger Liersch; Heike Hintelmann; Johannes Dreischalück; Janine Ring; Christoph Bremer; Walter Heindel; Rolf M Mesters; Wolfgang E Berdel
Tissue-factor fusion proteins induce occlusion of tumor vessels.
Thrombosis research 2010;125 Suppl 2():S143-50.
2010: Michele Pohlen; Bülent Sargin; Stefan Zicholl; Guido Bisping; Carsten Müller-Tidow; Wolfgang E Berdel; Rolf Mesters; Steffen Koschmieder
Combination of romiplostim and rituximab: effective therapy of severe immune thrombocytopenia.
European journal of haematology 2010;84(4):362-4.
2010: Annika Dufour; Friederike Schneider; Klaus Metzeler; Eva Hoster; Stephanie Schneider; Evelyn Zellmeier; Tobias Benthaus; Maria Cristina Sauerland; Wolfgang E Berdel; Thomas Büchner; Bernhard Wörmann; Jan Braess; Wolfgang Hiddemann; Stefan K Bohlander; Karsten Spiekermann
Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(4):570-7.
2010: Walter Fiedler; Rolf M Mesters; Michael Heuser; Gerhard Ehninger; Wolfgang E Berdel; Ute Zirrgiebel; Jane D Robertson; Tom A Puchalski; Barbara Collins; Juliane M Jürgensmeier; Hubert Serve
An open-label, Phase I study of cediranib (RECENTIN) in patients with acute myeloid leukemia.
Leukemia research 2010;34(2):196-202.
2010: Rolf Fendel; Christian Brandts; Annika Rudat; Andrea Kreidenweiss; Claudia Steur; Iris Appelmann; Bettina Ruehe; Paul Schröder; Wolfgang E Berdel; Song Le; Benjamin Mordmüller
Hemolysis is associated with low reticulocyte production index and predicts blood transfusion in severe malarial anemia.
PloS one 2010;5(4):e10038.
2010: Torsten Kessler; Michael Bayer; Christian Schwöppe; Rüdiger Liersch; Rolf M Mesters; Wolfgang E Berdel
Compounds in clinical Phase III and beyond.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2010;180():137-63.
2010: Rüediger Liersch; Christoph Biermann; Rolf M Mesters; Wolfgang E Berdel
Lymphangiogenesis in cancer: current perspectives.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2010;180():115-35.
2010: Iris Appelmann; Rüdiger Liersch; Torsten Kessler; Rolf M Mesters; Wolfgang E Berdel
Angiogenesis inhibition in cancer therapy: platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF) and their receptors: biological functions and role in malignancy.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2010;180():51-81.
2010: Wolfgang E Berdel
Angiogenesis inhibition. Introduction.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2010;180():1.
2009: Eva Lengfelder; Claudia Haferlach; Susanne Saussele; Torsten Haferlach; Beate Schultheis; S Schnittger; Wolf-Dieter Ludwig; Peter Staib; Carlo Aul; A Grüneisen; W Kern; A Reichle; Hubert Serve; Wolfgang E Berdel; J Braess; K Spiekermann; Bernhard Wörmann; Maria Cristina Sauerland; Achim Heinecke; Wolfgang Hiddemann; Rüdiger Hehlmann; Thomas Büchner
High dose ara-C in the treatment of newly diagnosed acute promyelocytic leukemia: long-term results of the German AMLCG.
Leukemia 2009;23(12):2248-58.
2009: Srinivasa Rao Bandi; Christian Brandts; Marion Rensinghoff; Rebekka Grundler; Lara Tickenbrock; Gabriele Köhler; Justus Duyster; Wolfgang E Berdel; Carsten Müller-Tidow; Hubert Serve; Bülent Sargin
E3 ligase-defective Cbl mutants lead to a generalized mastocytosis and myeloproliferative disease.
Blood 2009;114(19):4197-208.
2009: Martin Kropff; Peter Liebisch; Stefan Knop; Katja Weisel; Hannes Wand; Claudia-Nanette Gann; Wolfgang E Berdel; Hermann Einsele
DSMM XI study: dose definition for intravenous cyclophosphamide in combination with bortezomib/dexamethasone for remission induction in patients with newly diagnosed myeloma.
Annals of hematology 2009;88(11):1125-30.
2009: Chunaram Choudhary; Jesper V Olsen; Christian Brandts; Jürgen Cox; NG Pavankumar Reddy; Frank D Böhmer; Volker Gerke; Dirk-E Schmidt-Arras; Wolfgang E Berdel; Carsten Müller-Tidow; Matthias Mann; Hubert Serve
Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes.
Molecular cell 2009;36(2):326-39.
2009: Klaus Metzeler; Annika Dufour; Tobias Benthaus; Manuela Hummel; Maria Cristina Sauerland; Achim Heinecke; Wolfgang E Berdel; Thomas Büchner; Bernhard Wörmann; Ulrich Mansmann; Jan Braess; Karsten Spiekermann; Wolfgang Hiddemann; Christian Buske; Stefan K Bohlander
ERG expression is an independent prognostic factor and allows refined risk stratification in cytogenetically normal acute myeloid leukemia: a comprehensive analysis of ERG, MN1, and BAALC transcript levels using oligonucleotide microarrays.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(30):5031-8.
2009: Martin Kropff; Joachim Kienast; Guido Bisping; Wolfgang E Berdel; Birgit Gaschler-Markefski; Peter Stopfer; Martin Stefanic; Gerd Munzert
An open-label dose-escalation study of BIBF 1120 in patients with relapsed or refractory multiple myeloma.
Anticancer research 2009;29(10):4233-8.
2009: Iris Appelmann; Tobias Linden; Annika Rudat; Carsten Mueller-Tidow; Wolfgang E Berdel; Rolf M Mesters
Hereditary thrombocytopenia and acute myeloid leukemia: a common link due to a germline mutation in the AML1 gene.
Annals of hematology 2009;88(10):1037-8.
2009: Jun Yu; Etmar Bulk; Ping Ji; Antje Hascher; Steffen Koschmieder; Wolfgang E Berdel; Carsten Müller-Tidow
The kinase defective EPHB6 receptor tyrosine kinase activates MAP kinase signaling in lung adenocarcinoma.
International journal of oncology 2009;35(1):175-9.
2009: Michael Kreuter; M Kropff; A Fischaleck; K Junker; J Gerss; Achim Heinecke; M Lindermann; Niels Reinmuth; Wolfgang E Berdel; Rolf M Mesters; Michael Thomas
Prognostic relevance of angiogenesis in stage III NSCLC receiving multimodality treatment.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2009;33(6):1383-8.
2009: Friederike Schneider; Eva Hoster; Michael Unterhalt; Stephanie Schneider; Annika Dufour; Tobias Benthaus; Gudrun Mellert; Evelin Zellmeier; Stefan K Bohlander; Michaela Feuring-Buske; Christian Buske; Jan Braess; Susanne Fritsch; Achim Heinecke; Maria C Sauerland; Wolfgang E Berdel; Thomas Buechner; Bernhard J Woermann; Wolfgang Hiddemann; Karsten Spiekermann
NPM1 but not FLT3-ITD mutations predict early blast cell clearance and CR rate in patients with normal karyotype AML (NK-AML) or high-risk myelodysplastic syndrome (MDS).
Blood 2009;113(21):5250-3.
2009: Ralf Bieker; Torsten Kessler; Christian Schwöppe; Teresa Padró; Thorsten Persigehl; Christoph Bremer; Johannes Dreischalück; Astrid Kolkmeyer; Walter Heindel; Rolf M Mesters; Wolfgang E Berdel
Infarction of tumor vessels by NGR-peptide-directed targeting of tissue factor: experimental results and first-in-man experience.
Blood 2009;113(20):5019-27.
2009: Jan Braess; Karsten Spiekermann; Peter Staib; Andreas Grüneisen; Bernhard Wörmann; Wolf-Dieter Ludwig; Hubert Serve; Albrecht Reichle; Rudolf Peceny; Daniel Oruzio; Christoph Schmid; Xaver Schiel; Marcus Hentrich; Christina Sauerland; Michael Unterhalt; Michael Fiegl; Wolfgang Kern; Christian Buske; Stefan Bohlander; Achim Heinecke; Herrad Baurmann; Dietrich W Beelen; Wolfgang E Berdel; Thomas Büchner; Wolfgang Hiddemann
Dose-dense induction with sequential high-dose cytarabine and mitoxantone (S-HAM) and pegfilgrastim results in a high efficacy and a short duration of critical neutropenia in de novo acute myeloid leukemia: a pilot study of the AMLCG.
Blood 2009;113(17):3903-10.
2009: Ralf Metzger; Daniel Vallbohmer; Carsten Müller-Tidow; Hiroshi Higashi; Elfriede Bollschweiler; Ute Warnecke-Eberz; Jan Brabender; Stephan E Baldus; Huan Xi; Wolfgang E Berdel; Hubert Serve; Arnulf H Hoelscher; Paul M Schneider
Increased human telomerase reverse transcriptase (hTERT) mRNA expression but not telomerase activity is related to survival in curatively resected non-small cell lung cancer.
Anticancer research 2009;29(4):1157-62.
2009: Utz Krug; Thomas Buchner; Till Fassbinder; Markus Gaubitz; Wolfgang E Berdel
Clinical image: Lupus erythematosus cells in ascites fluid.
Arthritis and rheumatism 2009;60(3):859.
2009: Guido Bisping; Doris Wenning; Martin Kropff; Dirk Gustavus; Carsten Müller-Tidow; Matthias Stelljes; Gerd Munzert; Frank Hilberg; Gerald J Roth; Martin Stefanic; Sarah Volpert; Rolf M Mesters; Wolfgang E Berdel; Joachim Kienast
Bortezomib, dexamethasone, and fibroblast growth factor receptor 3-specific tyrosine kinase inhibitor in t(4;14) myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(2):520-31.
2009: Jun Yu; Helena Müller; Sina Hehn; Steffen Koschmieder; Kai Schönig; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
Construction and application of an inducible system for homogenous expression levels in bulk cell lines.
PloS one 2009;4(7):e6445.
2009: Etmar Bulk; Bülent Sargin; Utz Krug; Antje Hascher; Yu Jun; Markus Knop; Claus Kerkhoff; Volker Gerke; Ruediger Liersch; Rolf M Mesters; Marc Hotfilder; Alessandro Marra; Steffen Koschmieder; Martin Dugas; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
S100A2 induces metastasis in non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(1):22-9.
2009: Thomas Büchner; Wolfgang E Berdel; Claudia Haferlach; Torsten Haferlach; Susanne Schnittger; Carsten Müller-Tidow; Jan Braess; Karsten Spiekermann; Joachim Kienast; Peter Staib; Andreas Grüneisen; Wolfgang Kern; Albrecht Reichle; Georg Maschmeyer; Carlo Aul; Eva Lengfelder; Maria Cristina Sauerland; Achim Heinecke; Bernhard Wörmann; Wolfgang Hiddemann
Age-related risk profile and chemotherapy dose response in acute myeloid leukemia: a study by the German Acute Myeloid Leukemia Cooperative Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(1):61-9.
2008: Lara Tickenbrock; Sina Hehn; Bülent Sargin; Chunaram Choudhary; Nicole Bäumer; Horst Buerger; Bernd Schulte; Oliver Müller; Wolfgang E Berdel; Carsten Müller-Tidow; Hubert Serve
Activation of Wnt signalling in acute myeloid leukemia by induction of Frizzled-4.
International journal of oncology 2008;33(6):1215-21.
2008: Klaus Metzeler; Manuela Hummel; Clara D Bloomfield; Karsten Spiekermann; Jan Braess; Maria-Cristina Sauerland; Achim Heinecke; Michael Radmacher; Guido Marcucci; Susan P Whitman; Kati Maharry; Peter Paschka; Richard A Larson; Wolfgang E Berdel; Thomas Büchner; Bernhard Wörmann; Ulrich Mansmann; Wolfgang Hiddemann; Stefan K Bohlander; Christian Buske
An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia.
Blood 2008;112(10):4193-201.
2008: Michael Mormann; Johannes Eble; Christian Schwöppe; Rolf M Mesters; Wolfgang E Berdel; Jasna Peter-Katalinić; Gottfried Pohlentz
Fragmentation of intra-peptide and inter-peptide disulfide bonds of proteolytic peptides by nanoESI collision-induced dissociation.
Analytical and bioanalytical chemistry 2008;392(5):831-8.
2008: Nils Thoennissen; Kathy Keyvani; Hans U Voelker; Janbernd Bremer; Utz Krug; Carsten Müller-Tidow; Peter Koch; Hans K Müller-Hermelink; Wolfgang E Berdel
Splenic marginal zone lymphoma: transformation to diffuse large B-cell lymphoma with isolated cerebral manifestation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(27):4509-11.
2008: Lara Tickenbrock; Sina Hehn; Bülent Sargin; Georg Evers; Pavankumar Reddy Ng; Chunaram Choudhary; Wolfgang E Berdel; Carsten Müller-Tidow; Hubert Serve
Activation of Wnt signaling in cKit-ITD mediated transformation and imatinib sensitivity in acute myeloid leukemia.
International journal of hematology 2008;88(2):174-80.
2008: T Meister; H Heinzow; Guido Bisping; Matthias Stelljes; B Schulte; Wolfgang E Berdel; Joachim Kienast; Wolfram Domschke; Hansjörg Ullerich
Intestinal graft-versus-host-disease staging by video capsule endoscopy.
Endoscopy 2008;40 Suppl 2():E144.
2008: E Schmidt; Nils Thoennissen; A Rudat; Ralf Bieker; Christoph Schliemann; Rolf M Mesters; Michael Zühlsdorf; C Müller-Tidow; Wolfgang E Berdel
Use of palifermin for the prevention of high-dose methotrexate-induced oral mucositis.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(9):1644-9.
2008: Thomas Büchner; Wolfgang E Berdel; Joachim Kienast
Cytogenetically normal acute myeloid leukemia.
The New England journal of medicine 2008;359(6):651; author reply 652-3.
2008: Michael Thomas; Christian Rübe; Petra Hoffknecht; Hans-Nicol Macha; Lutz Freitag; Albert Linder; Normann Willich; Michael Hamm; Gerhard W Sybrecht; Dieter Ukena; Karl-Matthias Deppermann; Cornelia Dröge; Dorothea Riesenbeck; Achim Heinecke; Cristina Sauerland; Klaus Junker; Wolfgang E Berdel; Michael Semik
Effect of preoperative chemoradiation in addition to preoperative chemotherapy: a randomised trial in stage III non-small-cell lung cancer.
The lancet oncology 2008;9(7):636-48.
2008: Axel R Zander; C Schmoor; Nicolaus Kröger; W Krüger; Volker Möbus; Norbert Frickhofen; Bernd Metzner; Wolfgang E Berdel; M Koenigsmann; E Thiel; Hannes Wandt; K Possinger; R Kreienberg; Martin Schumacher; W Jonat
Randomized trial of high-dose adjuvant chemotherapy with autologous hematopoietic stem-cell support versus standard-dose chemotherapy in breast cancer patients with 10 or more positive lymph nodes: overall survival after 6 years of follow-up.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(6):1082-9.
2008: Ruediger Liersch; Christoph Schliemann; Ralf Bieker; Heike Hintelmann; Thomas Buechner; Wolfgang E Berdel; Rolf M Mesters
Expression of VEGF-C and its receptor VEGFR-3 in the bone marrow of patients with acute myeloid leukaemia.
Leukemia research 2008;32(6):954-61.
2008: O Gluz; Ulrike Nitz; N Harbeck; E Ting; R Kates; A Herr; W Lindemann; Christian Jackisch; Wolfgang E Berdel; H Kirchner; Bernd Metzner; F Werner; G Schütt; Markus Frick; Christopher Poremba; R Diallo-Danebrock; Svjetlana Mohrmann
Triple-negative high-risk breast cancer derives particular benefit from dose intensification of adjuvant chemotherapy: results of WSG AM-01 trial.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(5):861-70.
2008: Etmar Bulk; Antje Hascher; Ruediger Liersch; Rolf M Mesters; Sven Diederichs; Bülent Sargin; Volker Gerke; Marc Hotfilder; Josef Vormoor; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
Adjuvant therapy with small hairpin RNA interference prevents non-small cell lung cancer metastasis development in mice.
Cancer research 2008;68(6):1896-904.
2008: Torsten Kessler; Christian Schwöppe; Ruediger Liersch; Christoph Schliemann; Heike Hintelmann; Ralf Bieker; Wolfgang E Berdel; Rolf M Mesters
Generation of fusion proteins for selective occlusion of tumor vessels.
Current drug discovery technologies 2008;5(1):1-8.
2008: Matthias Stelljes; Sven Hermann; Jörn Albring; Gabriele Köhler; Markus Loeffler; Christiane Franzius; Christopher Poremba; Verena Schlösser; Sarah Volkmann; Corinna Opitz; Christoph Bremer; Torsten Kucharzik; Gerda Silling; Otmar Schober; Wolfgang E Berdel; Michael Schäfers; Joachim Kienast
Clinical molecular imaging in intestinal graft-versus-host disease: mapping of disease activity, prediction, and monitoring of treatment efficiency by positron emission tomography.
Blood 2008;111(5):2909-18.
2008: Claudia Hoemme; Abdul Peerzada; Gerhard Behre; Yipeng Wang; Michael McClelland; Kay Nieselt; Matthias Zschunke; Christine Disselhoff; Shuchi Agrawal; Fabienne Isken; Nicola Tidow; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
Chromatin modifications induced by PML-RARalpha repress critical targets in leukemogenesis as analyzed by ChIP-Chip.
Blood 2008;111(5):2887-95.
2008: Torsten Kessler; M Mohr; Carsten Müller-Tidow; U Krug; U Brunnberg; B Mohr; Christoph Schliemann; Cristina Sauerland; Hubert Serve; Thomas Büchner; Wolfgang E Berdel; Rolf M Mesters
Amsacrine containing induction therapy in elderly AML patients: comparison to standard induction regimens in a matched-pair analysis.
Leukemia research 2008;32(3):491-4.
2008: Martin Dugas; Matthias Lange; Wolfgang E Berdel; Carsten Müller-Tidow
Workflow to improve patient recruitment for clinical trials within hospital information systems - a case-study.
Trials 2008;9():2.
2008: Fabienne Isken; Björn Steffen; Sylvia Merk; Martin Dugas; Birgit Markus; Nicola Tidow; Michael Zühlsdorf; Thomas Illmer; Christian Thiede; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
Identification of acute myeloid leukaemia associated microRNA expression patterns.
British journal of haematology 2008;140(2):153-61.
2008: Shuchi Agrawal; Steffen Koschmieder; Nicole Bäumer; NG Pavankumar Reddy; Wolfgang E Berdel; Carsten Müller-Tidow; Hubert Serve
Pim2 complements Flt3 wild-type receptor in hematopoietic progenitor cell transformation.
Leukemia 2008;22(1):78-86.
2007: Beate Gleissner; Richard Schlenk; Martin Bornhäuser; Wolfgang E Berdel
Gemtuzumab ozogamicin (mylotarg) for the treatment of acute myeloid leukemia--ongoing trials.
Onkologie 2007;30(12):657-62.
2007: Thorsten Persigehl; Lars Matuszewski; Torsten Kessler; Alexander Wall; Norbert Meier; Wolfgang Ebert; Wolfgang E Berdel; Walter Heindel; Rolf M Mesters; Christoph Bremer
Prediction of antiangiogenic treatment efficacy by iron oxide enhanced parametric magnetic resonance imaging.
Investigative radiology 2007;42(12):791-6.
2007: Steffen Koschmieder; Francesco D'Alò; Hanna S Radomska; Christine Schöneich; Ji Suk Chang; Marina Konopleva; Susumu Kobayashi; Elena Levantini; Nanjoo Suh; Annalisa Di Ruscio; Maria Teresa Voso; Julie C Watt; Ramasamy Santhanam; Bülent Sargin; Andrew Lamb; Michael Andreeff; Michael B. Sporn; Danilo Perrotti; Wolfgang E Berdel; Carsten Müller-Tidow; Hubert Serve; Daniel G Tenen
CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer binding protein alpha.
Blood 2007;110(10):3695-705.
2007: Nicole Baumer; Marie-Luise Sandstede; Sven Diederichs; Gabriele Kohler; Carol Readhead; Ping Ji; Feng Zhang; Etmar Bulk; Jörg Gromoll; Wolfgang E Berdel; Hubert Serve; Carsten Muller-Tidow
Analysis of the genetic interactions between Cyclin A1, Atm and p53 during spermatogenesis.
Asian journal of andrology 2007;9(6):739-50.
2007: Michael Kreuter; Martin B Steins; Katja Woelke; Thomas Buechner; Wolfgang E Berdel; Rolf M Mesters
Downregulation of neuropilin-1 in patients with acute myeloid leukemia treated with thalidomide.
European journal of haematology 2007;79(5):392-7.
2007: Jan-Henrik Mikesch; Annika Rudat; Michael Zühlsdorf; Wolfgang E Berdel; Rolf M Mesters; Beate Conrad; Karsten Becker; Wolfgang Fegeler; Christoph Anthoni
Subcutaneous zygomycosis in neutropenia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(30):4844-5.
2007: Nils Thoennissen; Christoph Schliemann; U Brunnberg; E Schmidt; Annette Staebler; Lars Stegger; Christoph Bremer; Christina Schleicher; Rolf M Mesters; Carsten Müller-Tidow; Wolfgang E Berdel
Chemotherapy in metastatic malignant triton tumor: report on two cases.
Oncology reports 2007;18(4):763-7.
2007: Niels Reinmuth; Sonja Rensinghoff; Miriam Raedel; Nicole Fehrmann; Christian Schwöppe; Torsten Kessler; Guido Bisping; Frank Hilberg; Gerald J Roth; Wolfgang E Berdel; Michael Thomas; Rolf M Mesters
Paracrine interactions of vascular endothelial growth factor and platelet-derived growth factor in endothelial and lung cancer cells.
International journal of oncology 2007;31(3):621-6.
2007: Christoph Schliemann; Ralf Bieker; Nils Thoennissen; Joachim Gerss; Rüdiger Liersch; Torsten Kessler; Thomas Büchner; Wolfgang E Berdel; Rolf M Mesters
Circulating angiopoietin-2 is a strong prognostic factor in acute myeloid leukemia.
Leukemia 2007;21(9):1901-6.
2007: Ping Ji; Nicole Bäumer; Taijun Yin; Sven Diederichs; Feng Zhang; Carmela Beger; Karl Welte; Simone Fulda; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
DNA damage response involves modulation of Ku70 and Rb functions by cyclin A1 in leukemia cells.
International journal of cancer. Journal international du cancer 2007;121(4):706-13.
2007: Thomas Büchner; Utz Krug; Wolfgang E Berdel; Achim Heinecke; Maria Cristina Sauerland; Bernhard Wörmann; Wolfgang Hiddemann
Maintenance for acute myeloid leukemia revisited.
Current treatment options in oncology 2007;8(4):296-304.
2007: Martin Kropff; Guido Bisping; Elke Schuck; Peter Liebisch; Nicola Lang; Marcus Hentrich; Tobias Dechow; Nicolaus Kröger; Hans Salwender; Bernd Metzner; Orhan Sezer; Monika Engelhardt; Hans-Heinrich Wolf; Hermann Einsele; Sarah Volpert; Achim Heinecke; Wolfgang E Berdel; Joachim Kienast
Bortezomib in combination with intermediate-dose dexamethasone and continuous low-dose oral cyclophosphamide for relapsed multiple myeloma.
British journal of haematology 2007;138(3):330-7.
2007: Thorsten Persigehl; Ralf Bieker; Lars Matuszewski; Alexander Wall; Torsten Kessler; Hendrik Kooijman; Norbert Meier; Wolfgang Ebert; Wolfgang E Berdel; Walter Heindel; Rolf M Mesters; Christoph Bremer
Antiangiogenic tumor treatment: early noninvasive monitoring with USPIO-enhanced MR imaging in mice.
Radiology 2007;244(2):449-56.
2007: Jan-Henrik Mikesch; Björn Steffen; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
The emerging role of Wnt signaling in the pathogenesis of acute myeloid leukemia.
Leukemia 2007;21(8):1638-47.
2007: Bülent Sargin; Chunaram Choudhary; Nicola Crosetto; Mirko H H Schmidt; Rebekka Grundler; Marion Rensinghoff; Christine Thiessen; Lara Tickenbrock; Joachim Schwäble; Christian Brandts; Benjamin August; Steffen Koschmieder; Srinivasa Rao Bandi; Justus Duyster; Wolfgang E Berdel; Carsten Müller-Tidow; Ivan Dikic; Hubert Serve
Flt3-dependent transformation by inactivating c-Cbl mutations in AML.
Blood 2007;110(3):1004-12.
2007: Anja Lorch; Christian Kollmannsberger; Jörg Thomas Hartmann; Bernd Metzner; Ingo G H Schmidt-Wolf; Wolfgang E Berdel; Florian Weissinger; Jan Schleicher; Gerlinde Egerer; Antje Haas; Rebekka Schirren; Jörg Beyer; Carsten Bokemeyer; Oliver Rick
Single versus sequential high-dose chemotherapy in patients with relapsed or refractory germ cell tumors: a prospective randomized multicenter trial of the German Testicular Cancer Study Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(19):2778-84.
2007: Chunaram Choudhary; Christian Brandts; Joachim Schwable; Lara Tickenbrock; Bülent Sargin; Andrea Ueker; Frank-D Böhmer; Wolfgang E Berdel; Carsten Müller-Tidow; Hubert Serve
Activation mechanisms of STAT5 by oncogenic Flt3-ITD.
Blood 2007;110(1):370-4.
2007: L Zahiragic; Christoph Schliemann; Ralf Bieker; Nils Thoennissen; K Burow; C Kramer; M Zühlsdorf; Wolfgang E Berdel; Rolf M Mesters
Bevacizumab reduces VEGF expression in patients with relapsed and refractory acute myeloid leukemia without clinical antileukemic activity.
Leukemia 2007;21(6):1310-2.
2007: Shuchi Agrawal; Wolf-Karsten Hofmann; Nicola Tidow; Mathias Ehrich; Dirk van den Boom; Steffen Koschmieder; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia.
Blood 2007;109(9):3895-905.
2007: Rolf Fendel; Benjamin Mordmüller; Andrea Kreidenweiss; Annika Rudat; Claudia Steur; Christian Ambrosch; Max Kirstein; Wolfgang E Berdel; Song Le; Christian Brandts
New method to quantify erythrophagocytosis by autologous monocytes.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2007;71(4):258-64.
2007: Matthias Stelljes; Christiane Specht; Jörn Albring; Sarah Volkmann; Verena Schlösser; Hans-Gerd Pauels; Christopher Poremba; Guido Bisping; Corinna Opitz; christian scheffold; Gerda Silling; Michael Kiehl; Wolfgang E Berdel; Joachim Kienast
Differential requirement for a cellular type-1 immune response in tumor-associated versus alloantigen-targeted GvT effects.
Transplantation 2007;83(3):314-22.
2007: Torsten Kessler; Frauke Fehrmann; Ralf Bieker; Wolfgang E Berdel; Rolf M Mesters
Vascular endothelial growth factor and its receptor as drug targets in hematological malignancies.
Current drug targets 2007;8(2):257-68.
2007: Christian Brandts; Wolfgang E Berdel; Hubert Serve
Oncogenic signaling in acute myeloid leukemia.
Current drug targets 2007;8(2):237-46.
2007: Shuchi Agrawal; Matthias Unterberg; Steffen Koschmieder; Udo zur Stadt; Uta Brunnberg; Walter Verbeek; Thomas Büchner; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
DNA methylation of tumor suppressor genes in clinical remission predicts the relapse risk in acute myeloid leukemia.
Cancer research 2007;67(3):1370-7.
2007: Steffen Koschmieder; Shuchi Agrawal; Hanna S Radomska; Claudia S Huettner; Daniel G Tenen; Oliver G Ottmann; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
Decitabine and vitamin D3 differentially affect hematopoietic transcription factors to induce monocytic differentiation.
International journal of oncology 2007;30(2):349-55.
2007: Utz Krug; Hubert Serve; Carsten Müller-Tidow; Rolf M Mesters; Björn Steffen; Thomas Büchner; Wolfgang E Berdel
New molecular therapy targets in acute myeloid leukemia.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2007;176():243-62.
2007: Lars Matuszewski; Thorsten Persigehl; Alexander Wall; Norbert Meier; Ralf Bieker; Hendrik Kooijman; Bernd Tombach; Rolf M Mesters; Wolfgang E Berdel; Walter Heindel; Christoph Bremer
Assessment of bone marrow angiogenesis in patients with acute myeloid leukemia by using contrast-enhanced MR imaging with clinically approved iron oxides: initial experience.
Radiology 2007;242(1):217-24.
2007: Niels Reinmuth; Elisabeth Piegelbrock; Miriam Raedel; Nicole Fehrmann; Heike Hintelmann; Ruth Wagner; Wolfgang E Berdel; Michael Thomas; Lutz Freitag; Rolf M Mesters
Prognostic significance of vessel architecture and vascular stability in non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2007;55(1):53-60.
2006: Emma Kulimova; Elisabeth Oelmann; Guido Bisping; Joachim Kienast; Rolf M Mesters; Joachim Schwäble; Frank Hilberg; Gerald J Roth; Gerd Munzert; Martin Stefanic; Björn Steffen; Christian Brandts; Carsten Müller-Tidow; Astrid Kolkmeyer; Thomas Büchner; Hubert Serve; Wolfgang E Berdel
Growth inhibition and induction of apoptosis in acute myeloid leukemia cells by new indolinone derivatives targeting fibroblast growth factor, platelet-derived growth factor, and vascular endothelial growth factor receptors.
Molecular cancer therapeutics 2006;5(12):3105-12.
2006: Michael Kreuter; K Woelke; Ralf Bieker; Christoph Schliemann; Martin B Steins; Thomas Buechner; Wolfgang E Berdel; Rolf M Mesters
Correlation of neuropilin-1 overexpression to survival in acute myeloid leukemia.
Leukemia 2006;20(11):1950-4.
2006: Norbert Frickhofen; Wolfgang E Berdel; F Opri; R Haas; A Schneeweiss; Michael Sandherr; W Kuhn; D K Hossfeld; C Thomssen; Hermann Heimpel; R Kreienberg; Axel Hinke; Volker Möbus
Phase I/II trial of multicycle high-dose chemotherapy with peripheral blood stem cell support for treatment of advanced ovarian cancer.
Bone marrow transplantation 2006;38(7):493-9.
2006: Christoph Schliemann; Ralf Bieker; Teresa Padro; Torsten Kessler; Heike Hintelmann; Thomas Buchner; Wolfgang E Berdel; Rolf M Mesters
Expression of angiopoietins and their receptor Tie2 in the bone marrow of patients with acute myeloid leukemia.
Haematologica 2006;91(9):1203-11.
2006: J C Becker; Carsten Müller-Tidow; M Stolte; Takahiro Fujimori; Nicola Tidow; A M Ilea; Christian Brandts; Lara Tickenbrock; Hubert Serve; Wolfgang E Berdel; Wolfram Domschke; Thorsten Pohle
Acetylsalicylic acid enhances antiproliferative effects of the EGFR inhibitor gefitinib in the absence of activating mutations in gastric cancer.
International journal of oncology 2006;29(3):615-23.
2006: Michael Kreuter; Michael Paulussen; Johannes Boeckeler; Joachim Gerss; Horst Buerger; Caren Liebscher; Torsten Kessler; Heribert Jurgens; Wolfgang E Berdel; Rolf M Mesters
Clinical significance of Vascular Endothelial Growth Factor-A expression in Ewing's sarcoma.
European journal of cancer (Oxford, England : 1990) 2006;42(12):1904-11.
2006: Martin Kropff; Guido Bisping; Doris Wenning; Wolfgang E Berdel; Joachim Kienast
Proteasome inhibition in multiple myeloma.
European journal of cancer (Oxford, England : 1990) 2006;42(11):1623-39.
2006: Thomas Büchner; Wolfgang E Berdel; Claudia Schoch; Torsten Haferlach; Hubert Serve; Joachim Kienast; Susanne Schnittger; Wolfgang Kern; Joëlle Tchinda; Albrecht Reichle; Eva Lengfelder; Peter Staib; Wolf-Dieter Ludwig; Carlo Aul; Hartmut Eimermacher; Leopold Balleisen; Maria Cristina Sauerland; Achim Heinecke; Bernhard Wörmann; Wolfgang Hiddemann
Double induction containing either two courses or one course of high-dose cytarabine plus mitoxantrone and postremission therapy by either autologous stem-cell transplantation or by prolonged maintenance for acute myeloid leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(16):2480-9.
2006: Lara Tickenbrock; Joachim Schwäble; Anke Strey; Bülent Sargin; Sina Hehn; Marion Baas; Chunaram Choudhary; Volker Gerke; Wolfgang E Berdel; Carsten Müller-Tidow; Hubert Serve
Wnt signaling regulates transendothelial migration of monocytes.
Journal of leukocyte biology 2006;79(6):1306-13.
2006: Bertram Glaß; Marita Kloess; Martin Bentz; Günter Schlimok; Wolfgang E Berdel; Alfred Feller; Lorenz Trümper; Markus Loeffler; Michael Pfreundschuh; Norbert Schmitz
Dose-escalated CHOP plus etoposide (MegaCHOEP) followed by repeated stem cell transplantation for primary treatment of aggressive high-risk non-Hodgkin lymphoma.
Blood 2006;107(8):3058-64.
2006: M Pieper; christian scheffold; S Duwe; Claudia Rossig; Guido Bisping; Matthias Stelljes; T F Tedder; H Jurgens; Wolfgang E Berdel; Joachim Kienast
Immunotherapy of B-cell malignancies with genetically engineered human CD8+ natural killer T cells.
Leukemia 2006;20(4):729-32.
2006: Joëlle Tchinda; Sarah Volpert; Wolfgang E Berdel; Thomas Büchner; Jürgen Horst
Novel three-break rearrangement and cryptic translocations leading to colocalization of MYC and IGH signals in B-cell acute lymphoblastic leukemia.
Cancer genetics and cytogenetics 2006;165(2):180-4.
2006: Lara Tickenbrock; Carsten Müller-Tidow; Wolfgang E Berdel; Hubert Serve
Emerging Flt3 kinase inhibitors in the treatment of leukaemia.
Expert opinion on emerging drugs 2006;11(1):153-65.
2006: Guido Bisping; Martin Kropff; Doris Wenning; Britta Dreyer; Sergey Bessonov; Frank Hilberg; Gerald J Roth; Gerd Munzert; Martin Stefanic; Matthias Stelljes; christian scheffold; Carsten Müller-Tidow; Peter Liebisch; Nicola Lang; Joëlle Tchinda; Hubert Serve; Rolf M Mesters; Wolfgang E Berdel; Joachim Kienast
Targeting receptor kinases by a novel indolinone derivative in multiple myeloma: abrogation of stroma-derived interleukin-6 secretion and induction of apoptosis in cytogenetically defined subgroups.
Blood 2006;107(5):2079-89.
2006: Norbert Schmitz; Marita Kloess; Marcel Reiser; Wolfgang E Berdel; Bernd Metzner; Bernd Dorken; Michael Kneba; Lorenz Trumper; Markus Loeffler; Michael Pfreundschuh; Bertram Glaß
Four versus six courses of a dose-escalated cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) regimen plus etoposide (megaCHOEP) and autologous stem cell transplantation: early dose intensity is crucial in treating younger patients with poor prognosis aggressive lymphoma.
Cancer 2006;106(1):136-45.
2006: Oliver Albrecht; Hubert Serve; Joëlle Tchinda; Michael Zühlsdorf; Thomas Büchner; Christoph Bremer; Reza Parwaresch; Wolfgang E Berdel
Acute myeloid leukemia presenting with a uterus tumor.
Annals of hematology 2006;85(1):58-9.
2005: Ulrike Nitz; Svjetlana Mohrmann; Johannes Fischer; Walter Lindemann; Wolfgang E Berdel; Christian Jackisch; Christoph Werner; Carsten Ziske; Hartmut Kirchner; Bernd Metzner; Rainer Souchon; Ute Ruffert; Gerhart Schütt; Anke Pollmanns; Hans Joachim Schmoll; Constantin Middecke; Jörg Baltzer; Iris Schrader; Herrmann Wiebringhaus; Yon Ko; Siegfried Rösel; Thomas Schwenzer; Peter Wernet; Axel Hinke; Hans Georg Bender; Markus Frick
Comparison of rapidly cycled tandem high-dose chemotherapy plus peripheral-blood stem-cell support versus dose-dense conventional chemotherapy for adjuvant treatment of high-risk breast cancer: results of a multicentre phase III trial.
Lancet 2005;366(9501):1935-44.
2005: Tobias Lange; Carsten Müller-Tidow; Hubert Serve; Petra Hoffknecht; Wolfgang E Berdel; Michael Thomas
First-line systemic treatment with gefitinib in stage IV non-small cell lung cancer.
Oncology reports 2005;14(6):1539-42.
2005: Christian Brandts; Bülent Sargin; Miriam Rode; Christoph Biermann; Beate Lindtner; Joachim Schwäble; Horst Buerger; Carsten Müller-Tidow; Chunaram Choudhary; Martin McMahon; Wolfgang E Berdel; Hubert Serve
Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation.
Cancer research 2005;65(21):9643-50.
2005: Thomas Büchner; Wolfgang E Berdel; Bernhard Wörmann; Claudia Schoch; Torsten Haferlach; Susanne Schnittger; Wolfgang Kern; Carlo Aul; Eva Lengfelder; Andrea Schumacher; Albrecht Reichle; Peter Staib; Leopold Balleisen; Hartmut Eimermacher; Andreas Grüneisen; Herbert Rasche; Maria Cristina Sauerland; Achim Heinecke; Rolf M Mesters; Hubert Serve; Joachim Kienast; Wolfgang Hiddemann
Treatment of older patients with AML.
Critical reviews in oncology/hematology 2005;56(2):247-59.
2005: Björn Steffen; Carsten Müller-Tidow; Joachim Schwäble; Wolfgang E Berdel; Hubert Serve
The molecular pathogenesis of acute myeloid leukemia.
Critical reviews in oncology/hematology 2005;56(2):195-221.
2005: Wolfgang Hiddemann; Karsten Spiekermann; Christian Buske; Michaela Feuring-Buske; Jan Braess; Torsten Haferlach; Claudia Schoch; Wolfgang Kern; Susanne Schnittger; Wolfgang E Berdel; Bernhard Wörmann; Achim Heinecke; Cristina Sauerland; Thomas Büchner
Towards a pathogenesis-oriented therapy of acute myeloid leukemia.
Critical reviews in oncology/hematology 2005;56(2):235-45.
2005: Wolfgang E Berdel; Emma Kulimova; Astrid Kolkmeyer; Michael Zühlsdorf; Hubert Serve; Thomas Büchner; Elisabeth Oelmann
Receptor for platelet-activating factor (PAF) is not detectable by flow cytometry on the surface of myeloid leukemic cells.
Annals of hematology 2005;84(12):771-3.
2005: Matthias Stelljes; Martin Bornhauser; Matthias Kroger; Jörg Beyer; Maria Cristina Sauerland; Achim Heinecke; Bjorna Berning; christian scheffold; Gerda Silling; Thomas Buchner; Andreas Neubauer; Axel A Fauser; Gerhard Ehninger; Wolfgang E Berdel; Joachim Kienast
Conditioning with 8-Gy total body irradiation and fludarabine for allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia.
Blood 2005;106(9):3314-21.
2005: Gordon C Jayson; Jean-Pierre Armand; Wolfgang E Berdel
[Inhibition of angiogenesis by proteins, peptides and "small molecules"].
Onkologie 2005;28 Suppl 4():29-34.
2005: Wolfgang E Berdel; Jens Panse
[Value of angiogenesis inhibitors in tumor diseases--preclinical data]].
Onkologie 2005;28 Suppl 4():25-8.
2005: Peter Koch; Andreas Probst; Wolfgang E Berdel; Normann Willich; Gabriele Reinartz; Jens Brockmann; Rüdiger Liersch; Francisco del Valle; Hermann Clasen; Carsten Hirt; Regine Breitsprecher; Rudolf Schmits; Mathias Freund; Rainer Fietkau; Peter Ketterer; Eva-Maria Freitag; Margit Hinkelbein; Achim Heinecke; Reza Parwaresch; Markus Tiemann
Treatment results in localized primary gastric lymphoma: data of patients registered within the German multicenter study (GIT NHL 02/96).
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(28):7050-9.
2005: Torsten Kessler; Ralf Bieker; Teresa Padró; Christian Schwöppe; Thorsten Persigehl; Christoph Bremer; Michael Kreuter; Wolfgang E Berdel; Rolf M Mesters
Inhibition of tumor growth by RGD peptide-directed delivery of truncated tissue factor to the tumor vasculature.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(17):6317-24.
2005: Katarzyna Barczyk; Michael Kreuter; Juliusz Pryjma; Evan P Booy; Subbareddy Maddika; Saeid Ghavami; Wolfgang E Berdel; Johannes Roth; Marek Los
Serum cytochrome c indicates in vivo apoptosis and can serve as a prognostic marker during cancer therapy.
International journal of cancer. Journal international du cancer 2005;116(2):167-73.
2005: Sven Diederichs; Nicole Bäumer; Nikolaus Schultz; F Kent Hamra; Mark Schrader; Marie-Luise Sandstede; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
Expression patterns of mitotic and meiotic cell cycle regulators in testicular cancer and development.
International journal of cancer. Journal international du cancer 2005;116(2):207-17.
2005: Chunaram Choudhary; Carsten Müller-Tidow; Wolfgang E Berdel; Hubert Serve
Signal transduction of oncogenic Flt3.
International journal of hematology 2005;82(2):93-9.
2005: Christian G Erker; Martin B Steins; Rudolf-Josef Fischer; Joachim Kienast; Wolfgang E Berdel; Walter Sibrowski; Uwe Cassens
The influence of blood group differences in allogeneic hematopoietic peripheral blood progenitor cell transplantation.
Transfusion 2005;45(8):1382-90.
2005: Sing Yu Goldstein-Jackson; Georg Gosheger; Günter Delling; Wolfgang E Berdel; G Ulrich Exner; Gernot Jundt; Jan-Nicolas Machatschek; Andreas Zoubek; Heribert Jürgens; Stefan S Bielack
Extraskeletal osteosarcoma has a favourable prognosis when treated like conventional osteosarcoma.
Journal of cancer research and clinical oncology 2005;131(8):520-6.
2005: Chunaram Choudhary; Joachim Schwäble; Christian Brandts; Lara Tickenbrock; Bülent Sargin; Thomas Kindler; Thomas Fischer; Wolfgang E Berdel; Carsten Müller-Tidow; Hubert Serve
AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations.
Blood 2005;106(1):265-73.
2005: Martin Kropff; Guido Bisping; Doris Wenning; Sarah Volpert; Joëlle Tchinda; Wolfgang E Berdel; Joachim Kienast
Bortezomib in combination with dexamethasone for relapsed multiple myeloma.
Leukemia research 2005;29(5):587-90.
2005: Lara Tickenbrock; Joachim Schwäble; Markus Wiedehage; Björn Steffen; Bülent Sargin; Chunaram Choudhary; Christian Brandts; Wolfgang E Berdel; Carsten Müller-Tidow; Hubert Serve
Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction.
Blood 2005;105(9):3699-706.
2005: Ping Ji; Shuchi Agrawal; Sven Diederichs; Nicole Bäumer; Annette Becker; Thomas Cauvet; Sascha Kowski; Carmela Beger; Karl Welte; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
Cyclin A1, the alternative A-type cyclin, contributes to G1/S cell cycle progression in somatic cells.
Oncogene 2005;24(16):2739-44.
2005: Michael Kreuter; Stephan Retzlaff; U Enser-Weis; Wolfgang E Berdel; Rolf M Mesters
Acquired haemophilia in a patient with gram-negative urosepsis and bladder cancer.
Haemophilia : the official journal of the World Federation of Hemophilia 2005;11(2):181-5.
2005: Wenbing Wang; Ping Ji; Björn Steffen; Ralf Metzger; Paul M Schneider; Hartmut Halfter; Mark Schrader; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
Alterations of lymphoid enhancer factor-1 isoform expression in solid tumors and acute leukemias.
Acta biochimica et biophysica Sinica 2005;37(3):173-80.
2005: Carsten Müller-Tidow; Sven Diederichs; Etmar Bulk; Thorsten Pohle; Björn Steffen; Joachim Schwäble; Sylvia Plewka; Michael Thomas; Ralf Metzger; Paul M Schneider; Christian Brandts; Wolfgang E Berdel; Hubert Serve
Identification of metastasis-associated receptor tyrosine kinases in non-small cell lung cancer.
Cancer research 2005;65(5):1778-82.
2005: Richard Werkmeister; Thomas Fillies; Christoph Gaertner; Ulrich Joos; Wolfgang E Berdel
A clinical phase I/II trial of rhIL-4 applied topically in patients with oral squamous cell carcinomas to assess safety and therapeutic activity.
Oncology reports 2005;13(3):449-52.
2005: Joachim Schwäble; Chunaram Choudhary; Christian Thiede; Lara Tickenbrock; Bülent Sargin; Claudia Steur; Maike Rehage; Annika Rudat; Christian Brandts; Wolfgang E Berdel; Carsten Müller-Tidow; Hubert Serve
RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation.
Blood 2005;105(5):2107-14.
2005: Jenny Potratz; Barbara Mlody; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
In vivo analyses of UV-irradiation-induced p53 promoter binding using a novel quantitative real-time PCR assay.
International journal of oncology 2005;26(2):493-8.
2005: Walter Fiedler; Hubert Serve; Hartmut Döhner; Michael Schwittay; Oliver G Ottmann; Anne-Marie O'Farrell; Carlo Bello; Randy Allred; William C Manning; Julie M Cherrington; Sharianne G Louie; Weiru Hong; Nicoletta M Brega; Giorgio Massimini; Paul Scigalla; Wolfgang E Berdel; Dieter K Hossfeld
A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease.
Blood 2005;105(3):986-93.
2005: Beate Kempf-Bielack; Stefan S Bielack; Heribert Jürgens; Detlev Branscheid; Wolfgang E Berdel; G Ulrich Exner; Ulrich Göbel; Knut Helmke; Gernot Jundt; Hartmut Kabisch; Matthias Kevric; Thomas Klingebiel; Rainer Kotz; Rainer Maas; Rudolf Schwarz; Michael Semik; Jörn Treuner; Andreas Zoubek; Kurt Winkler
Osteosarcoma relapse after combined modality therapy: an analysis of unselected patients in the Cooperative Osteosarcoma Study Group (COSS).
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(3):559-68.
2005: Thomas Buechner; Wolfgang E Berdel; Claudia Schoch; Torsten Haferlach; Hubert Serve; Susanne Schnittger; Wolfgang Kern; Joëlle Tchinda; Albrecht Reichle; Peter Staib; Wolf-Dieter Ludwig; Carlo Aul; Maria Cristina Sauerland; Achim Heinecke; Bernhard Woermann; Wolfgang Hiddemann
Treatment of AML in biological subgroups.
Hematology (Amsterdam, Netherlands) 2005;10 Suppl 1():281-85.
2004: Michael Kreuter; Ralf Bieker; Stefan S Bielack; Tanja Auras; Horst Buerger; Georg Gosheger; Heribert Jurgens; Wolfgang E Berdel; Rolf M Mesters
Prognostic relevance of increased angiogenesis in osteosarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8531-7.
2004: Jennifer Worch; Lara Tickenbrock; Joachim Schwäble; Björn Steffen; Thomas Cauvet; Barbara Mlody; Horst Buerger; H Phillip Koeffler; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
The serine-threonine kinase MNK1 is post-translationally stabilized by PML-RARalpha and regulates differentiation of hematopoietic cells.
Oncogene 2004;23(57):9162-72.
2004: Joëlle Tchinda; Sarah Volpert; Martin Kropff; Wolfgang E Berdel; Joachim Kienast; Friedhelm Meinhardt; Jürgen Horst
Frequent gains of the short arm of chromosome 9 in multiple myeloma with normal G-banded karyotype detected by comparative genomic hybridization.
American journal of clinical pathology 2004;122(6):875-82.
2004: christian scheffold; M Kroeger; M Zuehlsdorf; Joëlle Tchinda; Gerda Silling; Guido Bisping; Matthias Stelljes; Thomas Buechner; Wolfgang E Berdel; Joachim Kienast
Prediction of relapse of acute myeloid leukemia in allogeneic transplant recipients by marrow CD34+ donor cell chimerism analysis.
Leukemia 2004;18(12):2048-50.
2004: Carsten Müller-Tidow; Ping Ji; Sven Diederichs; Jenny Potratz; Nicole Bäumer; Gabriele Köhler; Thomas Cauvet; Chunaram Choudary; Tiffany van der Meer; Wan-Yu Iris Chan; Conrad Nieduszynski; William H Colledge; Mary Carrington; H Phillip Koeffler; Anja Restle; Lisa Wiesmüller; Joëlle Sobczak-Thépot; Wolfgang E Berdel; Hubert Serve
The cyclin A1-CDK2 complex regulates DNA double-strand break repair.
Molecular and cellular biology 2004;24(20):8917-28.
2004: Elisabeth Oelmann; Susan Haghgu; Emma Kulimova; Rolf M Mesters; Joachim Kienast; Hermann Herbst; Christiane Schmitmann; Astrid Kolkmeyer; Hubert Serve; Wolfgang E Berdel
Influence of keratinocyte growth factor on clonal growth of epithelial tumor cells, lymphoma and leukemia cells and on sensitivity of tumor cells towards 5-fluorouracil in vitro.
International journal of oncology 2004;25(4):1001-12.
2004: Joëlle Tchinda; Thomas E Neumann; Sarah Volpert; Wolfgang E Berdel; Thomas Büchner; Jürgen Horst
Characterization of chromosomal rearrangements in hematological diseases using spectral karyotyping.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2004;13(3):190-5.
2004: Sven Diederichs; Etmar Bulk; Björn Steffen; Ping Ji; Lara Tickenbrock; Kerstin Lang; Kurt S Zänker; Ralf Metzger; Paul M Schneider; Volker Gerke; Michael Thomas; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
S100 family members and trypsinogens are predictors of distant metastasis and survival in early-stage non-small cell lung cancer.
Cancer research 2004;64(16):5564-9.
2004: Matthias Stelljes; Robert Strothotte; Hans-Gerd Pauels; Christopher Poremba; Michaela Milse; Christiane Specht; Jörn Albring; Guido Bisping; christian scheffold; Thomas Kammertoens; Elisabeth Oelmann; Gerda Silling; Wolfgang E Berdel; Joachim Kienast
Graft-versus-host disease after allogeneic hematopoietic stem cell transplantation induces a CD8+ T cell-mediated graft-versus-tumor effect that is independent of the recognition of alloantigenic tumor targets.
Blood 2004;104(4):1210-6.
2004: Sven Diederichs; Nicole Bäumer; Ping Ji; Stephan K Metzelder; Gregory E Idos; Thomas Cauvet; Wenbing Wang; Maria Möller; Sarah Pierschalski; Jörg Gromoll; Mark Schrader; H Phillip Koeffler; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
Identification of interaction partners and substrates of the cyclin A1-CDK2 complex.
The Journal of biological chemistry 2004;279(32):33727-41.
2004: Niels Reinmuth; Rolf M Mesters; Ralf Bieker; Petra Hoffknecht; Wolfgang E Berdel; Michael Thomas
Signal transduction pathways as novel therapy targets in lung cancer.
Lung cancer (Amsterdam, Netherlands) 2004;45 Suppl 2():S177-86.
2004: Michael Thomas; Petra Hoffknecht; Cornelia Droege; Andreas Baisch; Niels Reinmuth; Michael Kreuter; Tobias Lange; Wolfgang E Berdel
Non-small-cell lung cancer: multimodality approach in stage-III resectable disease.
Lung cancer (Amsterdam, Netherlands) 2004;45 Suppl 2():S99-105.
2004: Axel Kamischke; Herbert Jürgens; Lothar Hertle; Wolfgang E Berdel; Eberhard Nieschlag
Cryopreservation of sperm from adolescents and adults with malignancies.
Journal of andrology 2004;25(4):586-92.
2004: Martin B Steins; Teresa Padró; Carsten Schwaenen; Sandra Ruiz; Rolf M Mesters; Wolfgang E Berdel; Joachim Kienast
Overexpression of urokinase receptor and cell surface urokinase-type plasminogen activator in the human vessel wall with different types of atherosclerotic lesions.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2004;15(5):383-91.
2004: Axel R Zander; Nicolaus Kröger; C Schmoor; William H Krüger; Volker Möbus; Norbert Frickhofen; Bernd Metzner; W Schultze; Wolfgang E Berdel; M Koenigsmann; E Thiel; Hannes Wandt; K Possinger; Lorenz Trümper; R Kreienberg; Marion Carstensen; E H Schmidt; Fritz Jänicke; M Schumacher; Walter Jonat
High-dose chemotherapy with autologous hematopoietic stem-cell support compared with standard-dose chemotherapy in breast cancer patients with 10 or more positive lymph nodes: first results of a randomized trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(12):2273-83.
2004: Thomas Büchner; Wolfgang E Berdel; Wolfgang Hiddemann
Priming with granulocyte colony-stimulating factor--relation to high-dose cytarabine in acute myeloid leukemia.
The New England journal of medicine 2004;350(21):2215-6.
2004: Carsten Müller-Tidow; Björn Steffen; Thomas Cauvet; Lara Tickenbrock; Ping Ji; Sven Diederichs; Bülent Sargin; Gabriele Köhler; Matthias Stelljes; Elena Puccetti; Martin Ruthardt; Sven deVos; Scott W Hiebert; H Phillip Koeffler; Wolfgang E Berdel; Hubert Serve
Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.
Molecular and cellular biology 2004;24(7):2890-904.
2004: Andrea Schumacher; Dorothea Riesenbeck; Michael Braunheim; Dieter Wewers; Achim Heinecke; Michael Semik; Petra Hoffknecht; Hans-Nicol Macha; Folker Klinke; Ernst-Wilhelm Schmidt; Normann Willich; Wolfgang E Berdel; Michael Thomas
Combined modality treatment for locally advanced non-small cell lung cancer: preoperative chemoradiation does not result in a poorer quality of life.
Lung cancer (Amsterdam, Netherlands) 2004;44(1):89-97.
2004: Carsten Müller-Tidow; S K Metzelder; Horst Buerger; Jens Packeisen; Arnold Ganser; Gerhard Heil; K Kügler; G Adigüzel; Joachim Schwäble; Björn Steffen; Wolf-Dieter Ludwig; Achim Heinecke; Thomas Büchner; Wolfgang E Berdel; Hubert Serve
Expression of the p14ARF tumor suppressor predicts survival in acute myeloid leukemia.
Leukemia 2004;18(4):720-6.
2004: Carsten Müller-Tidow; Joachim Schwäble; Björn Steffen; Nicola Tidow; Burkhard Brandt; Kerstin Becker; Eric Schulze-Bahr; Hartmut Halfter; Ulf Vogt; Ralf Metzger; Paul M Schneider; Thomas Büchner; Christian Brandts; Wolfgang E Berdel; Hubert Serve
High-throughput analysis of genome-wide receptor tyrosine kinase expression in human cancers identifies potential novel drug targets.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(4):1241-9.
2004: Joachim Kienast; Wolfgang E Berdel
c-maf in multiple myeloma: an oncogene enhancing tumor-stroma interactions.
Cancer cell 2004;5(2):109-10.
2004: Joachim Kienast; Matthias Stelljes; Bjorna Berning; Matthias Kröger; Maria Cristina Sauerland; Achim Heinecke; Claudia Schoch; Bernhard Wörmann; Thomas Büchner; Wolfgang Hiddemann; Wolfgang E Berdel
Transplantation strategies in AML: AMLCG data.
Annals of hematology 2004;83 Suppl 1():S136-7.
2004: Thomas Büchner; Wolfgang Hiddemann; Wolfgang E Berdel; Bernhard Wörmann; Claudia Schoch; Christa Fonatsch; Helmut Löffler; Torsten Haferlach; Wolf-Dieter Ludwig; Georg Maschmeyer; Peter Staib; Leopold Balleisen; Andreas Grüneisen; Carlo Aul; Eva Lengfelder; Rüdiger Hehlmann; Wolfgang Kern; Hubert Serve; Rolf M Mesters; Hartmut Eimermacher; Norbert Frickhofen; Joachim Kienast; A Giagounidis; Maria Cristina Sauerland; Achim Heinecke
Subgroup specific therapy effects in AML: AMLCG data.
Annals of hematology 2004;83 Suppl 1():S100-1.
2004: W Kern; Torsten Haferlach; Claudia Schoch; Maria Cristina Sauerland; Achim Heinecke; Bernhard Wörmann; Wolfgang E Berdel; Thomas Büchner; Wolfgang Hiddemann
Risk-adapted therapy of AML: the AMLCG experience.
Annals of hematology 2004;83 Suppl 1():S49-51.
2004: Joëlle Tchinda; Sarah Volpert; Rüdiger Liersch; Michael Zühlsdorf; Hubert Serve; T Neumann; Ingo Kennerknecht; Wolfgang E Berdel; Thomas Büchner; Jürgen Horst
A cryptic insertion (17;15) on both chromosomes 17 with lack of PML-RARA expression in a case of atypical acute promyelocytic leukemia.
Leukemia 2004;18(1):183-6.
2003: Thomas Büchner; Wolfgang Hiddemann; Wolfgang E Berdel; Bernhard Wörmann; Claudia Schoch; Christa Fonatsch; Helmut Löffler; Torsten Haferlach; Wolf-Dieter Ludwig; Georg Maschmeyer; Peter Staib; Carlo Aul; Andreas Gruneisen; Eva Lengfelder; Norbert Frickhofen; Wolfgang Kern; Hubert Serve; Rolf M Mesters; Maria Cristina Sauerland; Achim Heinecke
6-Thioguanine, cytarabine, and daunorubicin (TAD) and high-dose cytarabine and mitoxantrone (HAM) for induction, TAD for consolidation, and either prolonged maintenance by reduced monthly TAD or TAD-HAM-TAD and one course of intensive consolidation by sequential HAM in adult patients at all ages with de novo acute myeloid leukemia (AML): a randomized trial of the German AML Cooperative Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(24):4496-504.
2003: Anne-Marie O'Farrell; James M Foran; Walter Fiedler; Hubert Serve; Ronald L Paquette; Maureen A Cooper; Helene A Yuen; Sharianne G Louie; Heidi Kim; Susan Nicholas; Michael C Heinrich; Wolfgang E Berdel; Carlo Bello; Mark Jacobs; Paul Scigalla; William C Manning; Stephen Kelsey; Julie M Cherrington
An innovative phase I clinical study demonstrates inhibition of FLT3 phosphorylation by SU11248 in acute myeloid leukemia patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(15):5465-76.
2003: Hans-J Schmoll; Christian Kollmannsberger; Bernd Metzner; Jörg Thomas Hartmann; Norbert Schleucher; Patrick Schöffski; Jan Schleicher; Oliver Rick; Jörg Beyer; Dieter K Hossfeld; Lothar Kanz; Wolfgang E Berdel; Reinhard Andreesen; Carsten Bokemeyer
Long-term results of first-line sequential high-dose etoposide, ifosfamide, and cisplatin chemotherapy plus autologous stem cell support for patients with advanced metastatic germ cell cancer: an extended phase I/II study of the German Testicular Cancer Study Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(22):4083-91.
2003: Joëlle Tchinda; Sarah Volpert; Nicole McNeil; Thomas Neumann; Ingo Kennerknecht; Thomas Ried; Thomas Büchner; Hubert Serve; Wolfgang E Berdel; Jürgen Horst; Eva Hilgenfeld
Multicolor karyotyping in acute myeloid leukemia.
Leukemia & lymphoma 2003;44(11):1843-53.
2003: Ralf Bieker; Teresa Padró; Julia Kramer; Martin B Steins; Torsten Kessler; Stephan Retzlaff; Federico Herrera; Joachim Kienast; Wolfgang E Berdel; Rolf M Mesters
Overexpression of basic fibroblast growth factor and autocrine stimulation in acute myeloid leukemia.
Cancer research 2003;63(21):7241-6.
2003: Johannes Schetelig; Sebastian Fetscher; Albrecht Reichle; Wolfgang E Berdel; Yves Beguin; Salut Brunet; Dolores Caballero; Ignazio Majolino; Hans Hagberg; Hans E Johnsen; Eva Kimby; Emilio Montserrat; Douglas Stewart; Adrian Copplestone; Wolf Rösler; Jindra Pavel; Dorothea Kingreen; Wolfgang Siegert
Long-term disease-free survival in patients with angioimmunoblastic T-cell lymphoma after high-dose chemotherapy and autologous stem cell transplantation.
Haematologica 2003;88(11):1272-8.
2003: Ralf Bieker; Torsten Kessler; Wolfgang E Berdel; Rolf M Mesters
Rituximab in combination with platinum-containing chemotherapy in patients with relapsed or primary refractory diffuse large B-cell lymphoma.
Oncology reports 2003;10(6):1915-7.
2003: Carsten Müller-Tidow; Björn Steffen; Wolfgang E Berdel; Hubert Serve
Redirection of oncoproteins to kill cancer cells.
Cell cycle (Georgetown, Tex.) 2003;2(6):531-3.
2003: Walter Fiedler; Rolf M Mesters; Heike Tinnefeld; Sonja Loges; Peter Staib; Ulrich Duhrsen; Michael Flasshove; Oliver G Ottmann; Wolfram Jung; Franco Cavalli; Rolf Kuse; Joerg Thomalla; Hubert Serve; Anne-Marie O'Farrell; Mark Jacobs; Nicoletta M Brega; Paul Scigalla; Dieter K Hossfeld; Wolfgang E Berdel
A phase 2 clinical study of SU5416 in patients with refractory acute myeloid leukemia.
Blood 2003;102(8):2763-7.
2003: Hermann Herbst; Michael Zühlsdorf; B Sinha; G Silling; R Kiefer; B Marschall; M Hausberg; A Böckers; U Gräwe; Wolfgang E Berdel; R P Nippert; W Domschke
["Problem-based learning--inflammation and transplantation": an integrated, subject-centred course in the clinical section of the medical curriculum at the medical school of the University of Muenster].
Gesundheitswesen (Bundesverband der Ärzte des Öffentlichen Gesundheitsdienstes (Germany)) 2003;65(10):579-84.
2003: Ping Ji; Sven Diederichs; Wenbing Wang; Sebastian Böing; Ralf Metzger; Paul M Schneider; Nicola Tidow; Burkhard Brandt; Horst Buerger; Etmar Bulk; Michael Thomas; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer.
Oncogene 2003;22(39):8031-41.
2003: Martin B Steins; Ralf Bieker; Teresa Padró; Torsten Kessler; Joachim Kienast; Wolfgang E Berdel; Rolf M Mesters
Thalidomide for the treatment of acute myeloid leukemia.
Leukemia & lymphoma 2003;44(9):1489-93.
2003: Amber Yasmeen; Wolfgang E Berdel; Hubert Serve; Carsten Müller-Tidow
E- and A-type cyclins as markers for cancer diagnosis and prognosis.
Expert review of molecular diagnostics 2003;3(5):617-33.
2003: Elisabeth Oelmann; Susan Haghgu; Emma Kulimova; Hubert Serve; Christiane Schmitmann; Wolfgang E Berdel
Re: Leptin--a growth factor in normal and malignant breast cells and for normal mammary gland development.
Journal of the National Cancer Institute 2003;95(15):1171-3; author reply 1173-4.
2003: Martin Kropff; Nicola Lang; Guido Bisping; Nicole Dominé; Georg Innig; Marcus Hentrich; Manfred Mitterer; Thomas Südhoff; Roland Fenk; Christian Straka; Achim Heinecke; Olaf M Koch; Helmut Ostermann; Wolfgang E Berdel; Joachim Kienast
Hyperfractionated cyclophosphamide in combination with pulsed dexamethasone and thalidomide (HyperCDT) in primary refractory or relapsed multiple myeloma.
British journal of haematology 2003;122(4):607-16.
2003: Björn Steffen; Hubert Serve; Wolfgang E Berdel; Shuchi Agrawal; Bryan Linggi; Thomas Büchner; Scott W Hiebert; Carsten Müller-Tidow
Specific protein redirection as a transcriptional therapy approach for t(8;21) leukemia.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(14):8448-53.
2003: Carsten Müller-Tidow; Michael Kiehl; Jürgen R Sindermann; Michael Probst; Nicola Banger; Michael Zühlsdorf; Ting-Chao Chou; Wolfgang E Berdel; Hubert Serve; Olaf M Koch
Synergistic growth inhibitory effects of interferon-alpha and lovastatin on bcr-abl positive leukemic cells.
International journal of oncology 2003;23(1):151-8.
2003: Ralf Bieker; Christian Lerchenmüller; Jürgen Wehmeyer; Hubert Serve; Rolf M Mesters; Thomas Büchner; Wolfgang E Berdel
Phase I study of liposomal daunorubicin in relapsed and refractory acute myeloid leukemia.
Oncology reports 2003;10(4):915-20.
2003: Annette Nolte; christian scheffold; Janina Slotty; Colette Huenefeld; Joachim L Schultze; Stefan Grabbe; Wolfgang E Berdel; Joachim Kienast
Generation of melanoma-specific cytotoxic T lymphocytes for allogeneic immunotherapy.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2003;26(3):257-69.
2003: Masao Mizuki; Joachim Schwable; Claudia Steur; Chunaram Choudhary; Shuchi Agrawal; Bülent Sargin; Björn Steffen; Itaru Matsumura; Yuzuru Kanakura; Frank-D Böhmer; Carsten Müller-Tidow; Wolfgang E Berdel; Hubert Serve
Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations.
Blood 2003;101(8):3164-73.
2003: Guido Bisping; Regine Leo; Doris Wenning; Berno Dankbar; Teresa Padró; Martin Kropff; christian scheffold; Matthias Kröger; Rolf M Mesters; Wolfgang E Berdel; Joachim Kienast
Paracrine interactions of basic fibroblast growth factor and interleukin-6 in multiple myeloma.
Blood 2003;101(7):2775-83.
2003: Carsten Müller-Tidow; Carol Readhead; Arthur H Cohen; Kamlesh Asotra; Gregory E Idos; Sven Diederichs; Thomas Cauvet; Rong Yang; Wolfgang E Berdel; Hubert Serve; H Phillip Koeffler
Successive increases in human cyclin A1 promoter activity during spermatogenesis in transgenic mice.
International journal of molecular medicine 2003;11(3):311-5.
2003: Carsten Müller-Tidow; Sven Diederichs; Mark Schrader; Ulf Vogt; Kurt Miller; Wolfgang E Berdel; Hubert Serve
Cyclin A1 is highly expressed in aggressive testicular germ cell tumors.
Cancer letters 2003;190(1):89-95.
2003: Toshifumi Ozaki; Silke Flege; Matthias Kevric; Norbert Lindner; Rainer Maas; Günter Delling; Rudolf Schwarz; Arthur R von Hochstetter; Mechthild Salzer-Kuntschik; Wolfgang E Berdel; Heribert Jürgens; G Ulrich Exner; Peter Reichardt; Regine Mayer-Steinacker; Volker Ewerbeck; Rainer Kotz; Winfried Winkelmann; Stefan S Bielack
Osteosarcoma of the pelvis: experience of the Cooperative Osteosarcoma Study Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(2):334-41.
2003: Wolfgang Kern; Torsten Haferlach; Claudia Schoch; Helmut Loffler; Winfried Gassmann; Achim Heinecke; Maria Cristina Sauerland; Wolfgang E Berdel; Thomas Buchner; Wolfgang Hiddemann
Early blast clearance by remission induction therapy is a major independent prognostic factor for both achievement of complete remission and long-term outcome in acute myeloid leukemia: data from the German AML Cooperative Group (AMLCG) 1992 Trial.
Blood 2003;101(1):64-70.
2002: Carsten Müller-Tidow; Claudia Steur; Masao Mizuki; Joachim Schwäble; Christian Brandts; Wolfgang E Berdel; Hubert Serve
[Mutations of growth factor receptor Flt3 in acute myeloid leukemia: transformation of myeloid cells by Ras-dependent and Ras-independent mechanisms].
Deutsche medizinische Wochenschrift (1946) 2002;127(42):2195-200.
2002: Teresa Padró; Ralf Bieker; Sandra Ruiz; Martin B Steins; Stephan Retzlaff; H Bürger; Thomas Büchner; Torsten Kessler; F Herrera; Joachim Kienast; Carsten Müller-Tidow; Hubert Serve; Wolfgang E Berdel; Rolf M Mesters
Overexpression of vascular endothelial growth factor (VEGF) and its cellular receptor KDR (VEGFR-2) in the bone marrow of patients with acute myeloid leukemia.
Leukemia 2002;16(7):1302-10.
2002: Bryan Linggi; Carsten Müller-Tidow; Louis van de Locht; Ming Hu; John Nip; Hubert Serve; Wolfgang E Berdel; Bert A van der Reijden; Dawn E Quelle; Janet D Rowley; John Cleveland; Joop H Jansen; Pier Paolo Pandolfi; Scott W Hiebert
The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia.
Nature medicine 2002;8(7):743-50.
2002: Niels Reinmuth; Burkhard Brandt; Michael Semik; Wolf-Peter Kunze; Richard Achatzy; Hans H Scheld; Petra Broermann; Wolfgang E Berdel; Hans-Nicol Macha; Michael Thomas
Prognostic impact of Cyfra21-1 and other serum markers in completely resected non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2002;36(3):265-70.
2002: Martin B Steins; Hubert Serve; Michael Zühlsdorf; Norbert Senninger; Michael Semik; Wolfgang E Berdel
Carboplatin/etoposide induces remission of metastasised malignant peripheral nerve tumours (malignant schwannoma) refractory to first-line therapy.
Oncology reports 2002;9(3):627-30.
2002: Stephan Retzlaff; Teresa Padró; Peter Koch; Elisabeth Oelmann; Norbert Lügering; Rolf M Mesters; Wolfgang E Berdel
Interleukin 8 and Flt3 ligand as markers of advanced disease in primary gastrointestinal non-Hodgkin's lymphoma.
Oncology reports 2002;9(3):525-7.
2002: Teresa Padró; Rolf M Mesters; Berno Dankbar; Heike Hintelmann; Ralf Bieker; Michael Kiehl; Wolfgang E Berdel; Joachim Kienast
The catalytic domain of endogenous urokinase-type plasminogen activator is required for the mitogenic activity of platelet-derived and basic fibroblast growth factors in human vascular smooth muscle cells.
Journal of cell science 2002;115(Pt 9):1961-71.
2002: Petra Broermann; Klaus Junker; Burkhard Brandt; Achim Heinecke; Lutz Freitag; Folker Klinke; Wolfgang E Berdel; Michael Thomas
Trimodality treatment in Stage III nonsmall cell lung carcinoma: prrognostic impact of K-ras mutations after neoadjuvant therapy.
Cancer 2002;94(7):2055-62.
2002: Andrea Schumacher; Dieter Wewers; Achim Heinecke; Cristina Sauerland; Olaf M Koch; Jürgen van de Loo; Thomas Büchner; Wolfgang E Berdel
Fatigue as an important aspect of quality of life in patients with acute myeloid leukemia.
Leukemia research 2002;26(4):355-62.
2002: Thomas Büchner; Wolfgang Hiddemann; Wolfgang E Berdel; Bernhard Wörmann; Claudia Schoch; Helmut Löffler; Torsten Haferlach; Andrea Schumacher; Peter Staib; Leopold Balleisen; Andreas Grüneisen; Herbert Rasche; Carlo Aul; Axel Heyll; Eva Lengfelder; Wolf-Dieter Ludwig; Georg Maschmeyer; Hartmut Eimermacher; Jochen Karow; Norbert Frickhofen; Wolf-Dietrich Hirschmann; Maria Cristina Sauerland
Acute myeloid leukemia: treatment over 60.
Reviews in clinical and experimental hematology 2002;6(1):46-59; discussion 86-7.
2002: Joëlle Tchinda; Sarah Volpert; Thomas Neumann; Ingo Kennerknecht; Jörg Ritter; Thomas Büchner; Wolfgang E Berdel; Jürgen Horst
Novel der(1)t(1;19) in two patients with myeloid neoplasias.
Cancer genetics and cytogenetics 2002;133(1):61-5.
2002: Martin B Steins; Teresa Padró; Ralf Bieker; Sandra Ruiz; Martin Kropff; Joachim Kienast; Torsten Kessler; Thomas Buechner; Wolfgang E Berdel; Rolf M Mesters
Efficacy and safety of thalidomide in patients with acute myeloid leukemia.
Blood 2002;99(3):834-9.
2002: Torsten Kessler; A Pfeifer; Steven A. Silletti; Rolf M Mesters; Wolfgang E Berdel; Inder M Verma; David A Cheresh
Matrix metalloproteinase/integrin interactions as target for anti-angiogenic treatment strategies.
Annals of hematology 2002;81 Suppl 2():S69-70.
2002: Elisabeth Oelmann; Michael Thomas; Hubert Serve; Joachim Kienast; Michael Zühlsdorf; M Mohr; Folker Klinke; G Dölken; Hans-Nicol Macha; E W Schmidt; Wolfgang E Berdel
Early tandem high-dose ifosfamide, carboplatin, etoposide therapy with stem cell rescue for small-cell lung cancer: brief report on the results of a phase-I/II trial.
Oncology 2002;63(3):248-53.
2002: Elisabeth Oelmann; Hermann Herbst; Michael Zühlsdorf; Oliver Albrecht; Annette Nolte; Christiane Schmitmann; Oliver Manzke; Volker Diehl; Harald Stein; Wolfgang E Berdel
Tissue inhibitor of metalloproteinases 1 is an autocrine and paracrine survival factor, with additional immune-regulatory functions, expressed by Hodgkin/Reed-Sternberg cells.
Blood 2002;99(1):258-67.
2001: Wolfgang E Berdel; Michael Zühlsdorf; R P Nippert; B Marschall; Markus J Wilhelm; F Stümpel; Hermann Herbst; Sabine Kliesch; F Ramsthaler; W Domschke
[Problem-based learning--interdisciplinary tumor medicine: an integrated model of the Munster University].
Onkologie 2001;24(6):587-94.
2001: W Fiedler; P Staib; Rolf Kuse; U Dührsen; Michael Flasshove; F Cavalli; D K Hossfeld; Wolfgang E Berdel
Role of angiogenesis inhibitors in acute myeloid leukemia.
Cancer journal (Sudbury, Mass.) 2001;7 Suppl 3():S129-33.
2001: Carsten Müller-Tidow; K Kügler; Sven Diederichs; S Klümpen; M Möller; Ulf Vogt; Ralf Metzger; Paul M Schneider; Wolfgang E Berdel; Hubert Serve
Loss of expression of HDAC-recruiting methyl-CpG-binding domain proteins in human cancer.
British journal of cancer 2001;85(8):1168-74.
2001: Peter Koch; Francisco del Valle; Wolfgang E Berdel; Normann Willich; B Reers; Wolfgang Hiddemann; B Grothaus-Pinke; Gabriele Reinartz; Jens Brockmann; A Temmesfeld; R Schmitz; Christian Rübe; Andreas Probst; G Jaenke; H Bodenstein; A Junker; C Pott; Juergen Schultze; Achim Heinecke; Reza Parwaresch; Markus Tiemann
Primary gastrointestinal non-Hodgkin's lymphoma: II. Combined surgical and conservative or conservative management only in localized gastric lymphoma--results of the prospective German Multicenter Study GIT NHL 01/92.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(18):3874-83.
2001: Peter Koch; Francisco del Valle; Wolfgang E Berdel; Normann Willich; B Reers; Wolfgang Hiddemann; B Grothaus-Pinke; Gabriele Reinartz; Jens Brockmann; A Temmesfeld; R Schmitz; Christian Rübe; Andreas Probst; G Jaenke; H Bodenstein; A Junker; C Pott; Juergen Schultze; Achim Heinecke; Reza Parwaresch; Markus Tiemann
Primary gastrointestinal non-Hodgkin's lymphoma: I. Anatomic and histologic distribution, clinical features, and survival data of 371 patients registered in the German Multicenter Study GIT NHL 01/92.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(18):3861-73.
2001: Rolf M Mesters; Teresa Padró; Martin B Steins; Ralf Bieker; Stephan Retzlaff; Torsten Kessler; Joachim Kienast; Wolfgang E Berdel
[Angiogenesis in patients with hematologic malignancies].
Onkologie 2001;24 Suppl 5():75-80.
2001: Michael Thomas; Petra Broermann; C Droege; C Lerchenmüller; Wolfgang E Berdel
Development of treatment strategies in locally advanced non-small cell lung cancer (take home messages).
Lung cancer (Amsterdam, Netherlands) 2001;33 Suppl 1():S91-7.
2001: Andrea Renz; Wolfgang E Berdel; Michael Kreuter; Claus Belka; Klaus Schulze-Osthoff; Marek Los
Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo.
Blood 2001;98(5):1542-8.
2001: Thomas Büchner; Wolfgang Hiddemann; Wolfgang E Berdel; Bernhard Wörmann; Helmut Löffler; Claudia Schoch; Torsten Haferlach; Wolf-Dieter Ludwig; Georg Maschmeyer; Peter Staib; R Andreesen; Leopold Balleisen; Detlef Haase; Hartmut Eimermacher; Carlo Aul; Herbert Rasche; J Uhlig; Andreas Grüneisen; H E Reis; J Hartlapp; Wolf-Dietrich Hirschmann; H J Weh; H J Pielken; Winfried Gassmann; Maria Cristina Sauerland; Achim Heinecke
Remission induction therapy: the more intensive the better?
Cancer chemotherapy and pharmacology 2001;48 Suppl 1():S41-4.
2001: Uwe Cassens; P H Momkvist; M Zuehlsdorf; M Mohr; Joachim Kienast; Wolfgang E Berdel; Walter Sibrowski
Kinetics of standardized large volume leukapheresis (LVL) in patients do not show a recruitment phenomenon of peripheral blood progenitor cells (PBPC).
Bone marrow transplantation 2001;28(1):13-20.
2001: Rolf M Mesters; Teresa Padró; Ralf Bieker; Martin B Steins; Michael Kreuter; M Göner; S Kelsey; Paul Scigalla; Walter Fiedler; Thomas Büchner; Wolfgang E Berdel
Stable remission after administration of the receptor tyrosine kinase inhibitor SU5416 in a patient with refractory acute myeloid leukemia.
Blood 2001;98(1):241-3.
2001: Eva Hilgenfeld; Hesed Padilla-Nash; Nicole McNeil; Turid Knutsen; Cristina Montagna; Joëlle Tchinda; Jürgen Horst; W D Ludwig; Hubert Serve; Thomas Büchner; Wolfgang E Berdel; E Schröck; Thomas Ried
Spectral karyotyping and fluorescence in situ hybridization detect novel chromosomal aberrations, a recurring involvement of chromosome 21 and amplification of the MYC oncogene in acute myeloid leukaemia M2.
British journal of haematology 2001;113(2):305-17.
2001: Carsten Müller-Tidow; Wenbing Wang; Gregory E Idos; Sven Diederichs; Rong Yang; Carol Readhead; Wolfgang E Berdel; Hubert Serve; M Saville; R Watson; H Phillip Koeffler
Cyclin A1 directly interacts with B-myb and cyclin A1/cdk2 phosphorylate B-myb at functionally important serine and threonine residues: tissue-specific regulation of B-myb function.
Blood 2001;97(7):2091-7.
2001: Christian Lerchenmüller; M Göner; Thomas Büchner; Wolfgang E Berdel
Rhinocerebral zygomycosis in a patient with acute lymphoblastic leukemia.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2001;12(3):415-9.
2001: Wolfgang E Berdel; T Heldmann; Eckhard Thiel
Long-term results of a phase-II-pilot trial on preoperative high-dose chemotherapy with stem cell rescue in patients with cancer of the upper gastrointestinal tract.
Oncology reports 2001;8(2):341-2.
2001: Carsten Müller-Tidow; C Bornemann; Sven Diederichs; A Westermann; S Klümpen; P Zuo; Wenbing Wang; Wolfgang E Berdel; Hubert Serve
Analyses of the genomic methylation status of the human cyclin A1 promoter by a novel real-time PCR-based methodology.
FEBS letters 2001;490(1-2):75-8.
2001: Carsten Müller-Tidow; Ralf Metzger; K Kügler; Sven Diederichs; Gregory E Idos; Michael Thomas; Barbara Dockhorn-Dworniczak; Paul M Schneider; H Phillip Koeffler; Wolfgang E Berdel; Hubert Serve
Cyclin E is the only cyclin-dependent kinase 2-associated cyclin that predicts metastasis and survival in early stage non-small cell lung cancer.
Cancer research 2001;61(2):647-53.
2001: M Mohr; F Dalmis; Eva Hilgenfeld; Elisabeth Oelmann; Michael Zühlsdorf; K Kratz-Albers; Annette Nolte; Christiane Schmitmann; D Onaldi-Mohr; Uwe Cassens; Hubert Serve; Walter Sibrowski; Joachim Kienast; Wolfgang E Berdel
Simultaneous immunomagnetic CD34+ cell selection and B-cell depletion in peripheral blood progenitor cell samples of patients suffering from B-cell non-Hodgkin's lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(1):51-7.
2001: Oliver Rick; Carsten Bokemeyer; Jörg Beyer; Jörg Thomas Hartmann; Nimrod Schwella; Dorothea Kingreen; S Neureither; Bernd Metzner; Jochen Casper; Hannes Wandt; F Hartmann; Hans-J Schmoll; Günter Derigs; Arthur Gerl; Wolfgang E Berdel; Lothar Kanz; Wolfgang Siegert
Salvage treatment with paclitaxel, ifosfamide, and cisplatin plus high-dose carboplatin, etoposide, and thiotepa followed by autologous stem-cell rescue in patients with relapsed or refractory germ cell cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(1):81-8.
2000: Masao Mizuki; R Fenski; Hartmut Halfter; Itaru Matsumura; R Schmidt; C Müller; W Grüning; K Kratz-Albers; S Serve; Claudia Steur; Thomas Büchner; Joachim Kienast; Yuzuru Kanakura; Wolfgang E Berdel; Hubert Serve
Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways.
Blood 2000;96(12):3907-14.
2000: C Müller; Rong Yang; Dorothy J Park; Hubert Serve; Wolfgang E Berdel; H Phillip Koeffler
The aberrant fusion proteins PML-RAR alpha and PLZF-RAR alpha contribute to the overexpression of cyclin A1 in acute promyelocytic leukemia.
Blood 2000;96(12):3894-9.
2000: Max E Scheulen; Ralf A Hilger; Carsten Oberhoff; Jochen Casper; Mathias Freund; K M Josten; M Bornhäuser; G Ehninger; Wolfgang E Berdel; Joachim Baumgart; Andreas Harstrick; Peter Bojko; H H Wolf; Adolf E Schindler; Siegfried Seeber
Clinical phase I dose escalation and pharmacokinetic study of high-dose chemotherapy with treosulfan and autologous peripheral blood stem cell transplantation in patients with advanced malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(11):4209-16.
2000: C Müller; Carol Readhead; Sven Diederichs; Gregory E Idos; Rong Yang; Nicola Tidow; Hubert Serve; Wolfgang E Berdel; H Phillip Koeffler
Methylation of the cyclin A1 promoter correlates with gene silencing in somatic cell lines, while tissue-specific expression of cyclin A1 is methylation independent.
Molecular and cellular biology 2000;20(9):3316-29.
2000: Teresa Padró; Sandra Ruiz; Ralf Bieker; H Bürger; Martin B Steins; Joachim Kienast; Thomas Büchner; Wolfgang E Berdel; Rolf M Mesters
Increased angiogenesis in the bone marrow of patients with acute myeloid leukemia.
Blood 2000;95(8):2637-44.
2000: Berno Dankbar; Teresa Padró; Regine Leo; B Feldmann; Martin Kropff; Rolf M Mesters; Hubert Serve; Wolfgang E Berdel; Joachim Kienast
Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma.
Blood 2000;95(8):2630-6.
2000: R Fenski; K Flesch; S Serve; Masao Mizuki; Elisabeth Oelmann; K Kratz-Albers; Joachim Kienast; Regine Leo; Stefan Schwartz; Wolfgang E Berdel; Hubert Serve
Constitutive activation of FLT3 in acute myeloid leukaemia and its consequences for growth of 32D cells.
British journal of haematology 2000;108(2):322-30.
1999: Martin B Steins; Teresa Padró; CX Li; Rolf M Mesters; Helmut Ostermann; Dieter Hammel; Hans H Scheld; Wolfgang E Berdel; Joachim Kienast
Overexpression of tissue-type plasminogen activator in atherosclerotic human coronary arteries.
Atherosclerosis 1999;145(1):173-80.
1999: Thomas Fietz; Wolfgang E Berdel; H Rieder; Birgit Reufi; Hartmut Hopp; Eckhard Thiel; Wolfgang Knauf
Culturing human umbilical cord blood: a comparison of mononuclear vs CD34+ selected cells.
Bone marrow transplantation 1999;23(11):1109-15.
1999: M Mohr; Eva Hilgenfeld; Thomas Fietz; B Hoppe; M Koenigsmann; M Hoffmann; Wolfgang Knauf; Uwe Cassens; Walter Sibrowski; Joachim Kienast; Eckhard Thiel; Wolfgang E Berdel
Efficacy and safety of simultaneous immunomagnetic CD34+ cell selection and breast cancer cell purging in peripheral blood progenitor cell samples used for hematopoietic rescue after high-dose therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(5):1035-40.
1999: Michael Thomas; Christian Rübe; Michael Semik; M von Eiff; Lutz Freitag; Hans-Nicol Macha; W Wagner; Folker Klinke; Hans H Scheld; Normann Willich; Wolfgang E Berdel; Klaus Junker
Impact of preoperative bimodality induction including twice-daily radiation on tumor regression and survival in stage III non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(4):1185.
1999: B Hoppe; M Mohr; A Roots-Weiss; Joachim Kienast; Wolfgang E Berdel
Improvement of tumor cell depletion by combining immunomagnetic positive selection of CD34-positive hematopoietic stem cells and negative selection (purging) of tumor cells.
Bone marrow transplantation 1999;23(8):809-17.
1999: Hubert Serve; K Flesch; S Serve; R Fenski; Wolfgang E Berdel
Expression and function of Flt3/flk2 in human tumor cell lines.
International journal of oncology 1999;14(4):765-70.
1999: Michael Thomas; Christian Rübe; Michael Semik; M von Eiff; Folker Klinke; Hans-Nicol Macha; Lutz Freitag; Hans H Scheld; Normann Willich; Wolfgang E Berdel; Klaus Junker
Trimodality therapy in stage III non-small cell lung cancer: prediction of recurrence by assessment of p185neu.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;13(2):424-9.
1998: M P Koenigsmann; Monika Koenigsmann; Michael Notter; M Neuloh; Carola Mücke; Eckhard Thiel; Wolfgang E Berdel
Adhesion molecules on peripheral blood-derived CD34+ cells: effects of cryopreservation and short-term ex vivo incubation with serum and cytokines.
Bone marrow transplantation 1998;22(11):1077-85.
1998: Agnieszka Korfel; Max E Scheulen; H J Schmoll; O Gründel; Andreas Harstrick; M Knoche; L M Fels; M Skorzec; F Bach; Joachim Baumgart; G Sass; Siegfried Seeber; Eckhard Thiel; Wolfgang E Berdel
Phase I clinical and pharmacokinetic study of titanocene dichloride in adults with advanced solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(11):2701-8.
1997: Thomas Fietz; Eva Hilgenfeld; Wolfgang E Berdel; Hartmut Hopp; U Wenzel; W Dohle; Eckhard Thiel; Wolfgang Knauf
Ex vivo expansion of human umbilical cord blood does not lead to co-expansion of contaminating maternal mononuclear cells.
Bone marrow transplantation 1997;20(12):1019-26.
1997: Elisabeth Oelmann; A Kraemer; Hubert Serve; Birgit Reufi; D Oberberg; Stephan Patt; Hermann Herbst; Harald Stein; Eckhard Thiel; Wolfgang E Berdel
Autocrine interleukin-1 receptor antagonist can support malignant growth of glioblastoma by blocking growth-inhibiting autocrine loop of interleukin-1.
International journal of cancer. Journal international du cancer 1997;71(6):1066-76.
1997: A Roots-Weiss; C Papadimitriou; Hubert Serve; B Hoppe; Monika Koenigsmann; Birgit Reufi; D Oberberg; Eckhard Thiel; Wolfgang E Berdel
The efficiency of tumor cell purging using immunomagnetic CD34+ cell separation systems.
Bone marrow transplantation 1997;19(12):1239-46.
1996: Wolfgang Knauf; Monika Koenigsmann; M Notter; B Hoppe; Birgit Reufi; D Oberberg; Eckhard Thiel; Wolfgang E Berdel
Peripheral blood progenitor cell mobilization with Dexa-Beam/G-CSF, ether lipid purging, and autologous transplantation after high-dose CBV treatment: a safe and effective regimen in patients with poor risk malignant lymphomas.
Leukemia & lymphoma 1996;23(3-4):305-11.
1996: H Brachwitz; U Lachmann; Y Thomas; Jürgen Bergmann; Wolfgang E Berdel; P Langen
Synthesis and antiproliferative activity of cytidine-5'-alkylphosphonophosphates and structurally related compounds.
Chemistry and physics of lipids 1996;83(1):77-85.
1996: Monika Koenigsmann; M Notter; Wolfgang Knauf; C A Papadimitriou; D Oberberg; Birgit Reufi; C Mücke; Eckhard Thiel; Wolfgang E Berdel
Chemopurging of peripheral blood-derived progenitor cells by alkyl-lysophospholipid and its effect on haematopoietic rescue after high-dose therapy.
Bone marrow transplantation 1996;18(3):549-57.
1996: Hubert Serve; E Oelmann; A Herweg; D Oberberg; S Serve; Birgit Reufi; C Mücke; A Minty; Eckhard Thiel; Wolfgang E Berdel
Inhibition of proliferation and clonal growth of human breast cancer cells by interleukin 13.
Cancer research 1996;56(15):3583-8.
1996: W R Vogler; Wolfgang E Berdel; RB Geller; J A Brochstein; R A Beveridge; W S Dalton; K B Miller; H M Lazarus
A phase II trial of autologous bone marrow transplantation (ABMT) in acute leukemia with edelfosine purged bone marrow.
Advances in experimental medicine and biology 1996;416():389-96.
1995: C A Papadimitriou; A Roots; Monika Koenigsmann; M Koenigsmann; C Mücke; E Oelmann; D Oberberg; Birgit Reufi; Eckhard Thiel; Wolfgang E Berdel
Immunomagnetic selection of CD34+ cells from fresh peripheral blood mononuclear cell preparations using two different separation techniques.
Journal of hematotherapy 1995;4(6):539-44.
1995: C A Papadimitriou; M S Topp; Hubert Serve; E Oelmann; Monika Koenigsmann; J Maurer; D Oberberg; Birgit Reufi; Eckhard Thiel; Wolfgang E Berdel
Recombinant human stem cell factor does exert minor stimulation of growth in small cell lung cancer and melanoma cell lines.
European journal of cancer (Oxford, England : 1990) 1995;31A(13-14):2371-8.
1995: E Oelmann; L Sreter; I Schuller; Hubert Serve; Monika Koenigsmann; B Wiedenmann; D Oberberg; Birgit Reufi; Eckhard Thiel; Wolfgang E Berdel
Nerve growth factor stimulates clonal growth of human lung cancer cell lines and a human glioblastoma cell line expressing high-affinity nerve growth factor binding sites involving tyrosine kinase signaling.
Cancer research 1995;55(10):2212-9.
1994: Wolfgang Knauf; Wolfgang E Berdel; A D Ho; Ernst D Kreuser; Eckhard Thiel
Combination of mitoxantrone and etoposide in the treatment of myelodysplastic syndromes transformed into acute myeloid leukemia.
Leukemia & lymphoma 1994;12(5-6):421-5.
1994: M Shoji; T Fukuhara; Elliott F Winton; Wolfgang E Berdel; W R Vogler
Different mechanisms of inhibition by alkyl-lysophospholipid and phorbol ester of granulocyte-macrophage colony-stimulating factor binding to human leukemic cell lines.
Experimental hematology 1994;22(1):13-8.
1993: H F Dietzfelbinger; D Kühn; M Zafferani; Axel R Hanauske; J Rastetter; Wolfgang E Berdel
Removal of breast cancer cells from bone marrow by in vitro purging with ether lipids and cryopreservation.
Cancer research 1993;53(16):3747-51.
1993: B M Zimmer; Wolfgang E Berdel; Wolf-Dieter Ludwig; M Notter; Birgit Reufi; Eckhard Thiel
Fatal spleen rupture during induction chemotherapy with rh GM-CSF priming for acute monocytic leukemia. Clinical case report and in vitro studies.
Leukemia research 1993;17(3):277-83.
1993: W R Vogler; Wolfgang E Berdel
Autologous bone marrow transplantation with alkyl-lysophospholipid-purged marrow.
Journal of hematotherapy 1993;2(1):93-102.
1992: Monika Koenigsmann; M Zafferani; S Danhauser-Riedl; Birgit Reufi; W J Houlihan; Eckhard Thiel; Wolfgang E Berdel
Lack of therapeutic effects of platelet activating factor antagonists in WEHI-3B leukemia, human xenotransplanted colorectal and lung cancer and Lewis-lung tumor in vivo.
Cancer letters 1992;67(2-3):145-56.
1992: W R Vogler; Wolfgang E Berdel; A C Olson; Elliott F Winton; Leonard T Heffner; D S Gordon
Autologous bone marrow transplantation in acute leukemia with marrow purged with alkyl-lysophospholipid.
Blood 1992;80(6):1423-9.
1992: Wolfgang E Berdel; S de Vos; J Maurer; D Oberberg; Z von Marschall; J K Schroeder; J Li; W D Ludwig; E D Kreuser; Eckhard Thiel
Recombinant human stem cell factor stimulates growth of a human glioblastoma cell line expressing c-kit protooncogene.
Cancer research 1992;52(12):3498-502.
1992: Wolfgang E Berdel; S Danhauser-Riedl; D Oberberg; M Zafferani
Effects of hematopoietic growth factors on malignant nonhematopoietic cells.
Seminars in oncology 1992;19(2 Suppl 4):41-5.
1992: R Herrmann; Wolfgang E Berdel
Therapeutic activity of a thioether-lipid conjugate of 1-beta-D-arabinofuranosylcytosine in human colorectal cancer xenografts.
Cancer research 1992;52(7):1865-7.
1992: Ernst D Kreuser; B K Keppler; Wolfgang E Berdel; A Piest; Eckhard Thiel
Synergistic antitumor interactions between newly synthesized ruthenium complexes and cytokines in human colon carcinoma cell lines.
Seminars in oncology 1992;19(2 Suppl 3):73-81.
1992: H F Dietzfelbinger; A Lang; D Oberberg; J Rastetter; Wolfgang E Berdel
Differential cytotoxicity of an ether lipid on lymphoma and bone marrow cells and its role in purging malignant lymphoid cells from remission bone marrow contaminated with tumor cells.
Experimental hematology 1992;20(2):178-83.
1992: Wolfgang E Berdel; W R Vogler; A C Olson
Alkyl-lysophospholipid purging for autologous bone marrow transplantation in acute leukemia in second or subsequent remission after extramedullary relapse.
Progress in clinical and biological research 1992;377():79-85.
1992: Wolfgang E Berdel; M Zafferani; R Senekowitsch; Ernst D Kreuser; Eckhard Thiel
Effect of interleukin-3 and granulocyte-macrophage colony-stimulating factor on growth of xenotransplanted human tumour cell lines in nude mice.
European journal of cancer (Oxford, England : 1990) 1992;28(2-3):377-80.
1991: C I Hong; C R West; R J Bernacki; Cameron K Tebbi; Wolfgang E Berdel
1-beta-D-arabinofuranosylcytosine conjugates of ether and thioether phospholipids. A new class of ara-C prodrug with improved antitumor activity.
Lipids 1991;26(12):1437-44.
1991: W R Vogler; A C Olson; S Okamoto; M Shoji; R L Raynor; J F Kuo; Wolfgang E Berdel; H Eibl; J Hajdu; H Nomura
Comparison of selective cytotoxicity of alkyl lysophospholipids.
Lipids 1991;26(12):1418-23.
1991: Hubert Serve; G Steinhauser; D Oberberg; Willy A Flegel; H Northoff; Wolfgang E Berdel
Studies on the interaction between interleukin 6 and human malignant nonhematopoietic cell lines.
Cancer research 1991;51(15):3862-6.
1991: Wolfgang E Berdel; D Oberberg; Birgit Reufi; Eckhard Thiel
Studies on the role of recombinant human erythropoietin in the growth regulation of human nonhematopoietic tumor cells in vitro.
Annals of hematology 1991;63(1):5-8.
1991: S Danhauser-Riedl; S B Felix; W J Houlihan; M Zafferani; G Steinhauser; D Oberberg; H Kalvelage; R Busch; J Rastetter; Wolfgang E Berdel
Some antagonists of platelet activating factor are cytotoxic for human malignant cell lines.
Cancer research 1991;51(1):43-8.
1991: S B Felix; G Baumann; M Niemczyk; Z Ahmad; T Hashemi; Wolfgang E Berdel
Effects of platelet-activating factor on beta- and H2-receptor-mediated increase of myocardial contractile force in isolated perfused guinea pig hearts.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1991;191(1):1-9.
1990: Wolfgang E Berdel; S Danhauser-Riedl; G Steinhauser; J Rastetter
Stimulation of clonal growth of human colorectal tumor cells by IL-3 and GM-CSF. Modulation of 5-FU cytotoxicity by GM-CSF.
Onkologie 1990;13(6):437-43.
1990: S B Felix; G Baumann; Z Ahmad; T Hashemi; M Niemczyk; Wolfgang E Berdel
Effects of platelet-activating factor on myocardial contraction and myocardial relaxation of isolated perfused guinea pig hearts.
Journal of cardiovascular pharmacology 1990;16(5):750-6.
1990: S Danhauser-Riedl; A Himmelmann; G Steinhauser; R Busch; W R Vogler; J Rastetter; Wolfgang E Berdel
Cytotoxic effects of hexadecylphosphocholine in neoplastic cell lines including drug-resistant sublines in vitro.
Journal of lipid mediators 1990;2(5):271-80.
1990: Wolfgang E Berdel
Ether lipids and derivatives as investigational anticancer drugs. A brief review.
Onkologie 1990;13(4):245-50.
1990: S B Felix; G Baumann; T Hashemi; M Niemczyk; Z Ahmad; Wolfgang E Berdel
Characterization of cardiovascular events mediated by platelet activating factor during systemic anaphylaxis.
Journal of cardiovascular pharmacology 1990;15(6):987-97.
1990: W R Vogler; A C Olson; Wolfgang E Berdel; S Okamoto; L Glasser
Purging leukemia remission marrows with alkyl-lysophospholipids, preclinical and clinical results.
Progress in clinical and biological research 1990;333():1-18; discussion 19-20.
1990: A W Himmelmann; S Danhauser-Riedl; G Steinhauser; R Busch; E J Modest; A Noseda; J Rastetter; W R Vogler; Wolfgang E Berdel
Cross-resistance pattern of cell lines selected for resistance towards different cytotoxic drugs to membrane-toxic phospholipids in vitro.
Cancer chemotherapy and pharmacology 1990;26(6):437-43.
1990: S B Felix; G Baumann; Wolfgang E Berdel
Systemic anaphylaxis--separation of cardiac reactions from respiratory and peripheral vascular events.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1990;190(4):239-52.
1990: S B Felix; A Steger; G Baumann; R Busch; G Ochsenfeld; Wolfgang E Berdel
Platelet-activating factor-induced coronary constriction in the isolated perfused guinea pig heart and antagonistic effects of the PAF antagonist WEB 2086.
Journal of lipid mediators 1990;2(1):9-20.
1989: H D Schick; S Danhauser-Riedl; E Amtmann; R Busch; A Reichert; G Steinhauser; J Rastetter; G Sauer; Wolfgang E Berdel
Antitumoral activity of a xanthate compound. II. Therapeutic studies in murine leukemia and tumor models in vivo.
Cancer letters 1989;46(2):149-52.
1989: H D Schick; E Amtmann; Wolfgang E Berdel; S Danhauser-Riedl; A Reichert; G Steinhauser; J Rastetter; G Sauer
Antitumoral activity of a xanthate compound. I. Cytotoxicity studies with neoplastic cell lines in vitro.
Cancer letters 1989;46(2):143-7.
1989: Wolfgang E Berdel; S Okamoto; S Danhauser-Riedl; C I Hong; Elliott F Winton; C R West; J Rastetter; W R Vogler
Therapeutic activity of 1-beta-D-arabinofuranosylcytosine conjugates of lipids in WEHI-3B leukemia in mice.
Experimental hematology 1989;17(4):364-7.
1989: Wolfgang E Berdel; S Danhauser-Riedl; G Steinhauser; Elliott F Winton
Various human hematopoietic growth factors (interleukin-3, GM-CSF, G-CSF) stimulate clonal growth of nonhematopoietic tumor cells.
Blood 1989;73(1):80-3.
1988: M Shoji; R L Raynor; Wolfgang E Berdel; W R Vogler; J F Kuo
Effects of thioether phospholipid BM 41.440 on protein kinase C and phorbol ester-induced differentiation of human leukemia HL60 and KG-1 cells.
Cancer research 1988;48(23):6669-73.
1988: S Okamoto; A C Olson; Wolfgang E Berdel; W R Vogler
Purging of acute myeloid leukemic cells by ether lipids and hyperthermia.
Blood 1988;72(5):1777-83.
1988: M Fromm; Wolfgang E Berdel; H D Schick; S Danhauser-Riedl; U Fink; W Remy; A Reichert; A Ankele; H W Präuer; J R Siewert
Phase I trial of the polyelectrolyte carbetimer administered i.v. once every four weeks.
Investigational new drugs 1988;6(3):189-94.
1988: Wolfgang E Berdel; H Knopf; M Fromm; H D Schick; R Busch; U Fink; A Sellschopp; J Rastetter
Influence of phase I early clinical trials on the quality of life of cancer patients. A pilot study.
Anticancer research 1988;8(3):313-21.
1988: Wolfgang E Berdel; S Danhauser; C I Hong; H D Schick; A Reichert; R Busch; J Rastetter; W R Vogler
Influence of 1-beta-D-arabinofuranosylcytosine conjugates of lipids on the growth and metastasis of Lewis lung carcinoma.
Cancer research 1988;48(4):826-9.
1987: Wolfgang E Berdel; M R Berger; H Falk; A Harstrick; S Danhauser; H D Schick; H J Schmoll; D Schmähl; W R Vogler; J Rastetter
Lack of therapeutic activity of the lipoidal amine CP-46,665 in rodent tumors and human non-seminomatous germ cell tumors growing in nude mice.
Cancer letters 1987;38(1-2):191-7.
1987: Wolfgang E Berdel; S Danhauser; H D Schick; C I Hong; C R West; M Fromm; U Fink; A Reichert; J Rastetter
Antineoplastic activity of conjugates of lipids and 1-beta-D-arabinofuranosylcytosine.
Lipids 1987;22(11):943-6.
1987: M Fromm; Wolfgang E Berdel; H D Schick; U Fink; W Pahlke; U Bicker; A Reichert; J Rastetter
Antineoplastic activity of the thioether lysophospholipid derivative BM 41.440 in vitro.
Lipids 1987;22(11):916-8.
1987: S Danhauser; Wolfgang E Berdel; H D Schick; M Fromm; A Reichert; U Fink; R Busch; H Eibl; J Rastetter
Structure-cytotoxicity studies on alkyl lysophospholipids and some analogs in leukemic blasts of human origin in vitro.
Lipids 1987;22(11):911-5.
1987: H D Schick; Wolfgang E Berdel; M Fromm; U Fink; U Jehn; K Ulm; A Reichert; H Eibl; C Unger; J Rastetter
Cytotoxic effects of ether lipids and derivatives in human nonneoplastic bone marrow cells and leukemic cells in vitro.
Lipids 1987;22(11):904-10.
1987: Wolfgang E Berdel; R Korth; A Reichert; W J Houlihan; U Bicker; H Nomura; W R Vogler; J Benveniste; J Rastetter
Lack of correlation between cytotoxicity of agonists and antagonists of platelet activating factor [paf-acether] in neoplastic cells and modulation of [3H]-paf-acether binding to platelets from humans in vitro.
Anticancer research 1987;7(6):1181-7.
1987: Wolfgang E Berdel
Ether lipids and analogs in experimental cancer therapy. A brief review of the Munich experience.
Lipids 1987;22(11):970-3.
1987: Wolfgang E Berdel; U Fink; J Rastetter
Clinical phase I pilot study of the alkyl lysophospholipid derivative ET-18-OCH3.
Lipids 1987;22(11):967-9.
1987: D B Herrmann; H A Neumann; Wolfgang E Berdel; M E Heim; M Fromm; D Boerner; U Bicker
Phase I trial of the thioether phospholipid analogue BM 41.440 in cancer patients.
Lipids 1987;22(11):962-6.
1986: C I Hong; S H An; D J Buchheit; A Nechaev; A J Kirisits; C R West; Wolfgang E Berdel
Nucleoside conjugates. 7. Synthesis and antitumor activity of 1-beta-D-arabinofuranosylcytosine conjugates of ether lipids.
Journal of medicinal chemistry 1986;29(10):2038-44.
1986: Wolfgang E Berdel; Daniel Von Hoff; C Unger; H D Schick; U Fink; A Reichert; H Eibl; J Rastetter
Ether lipid derivatives: antineoplastic activity in vitro and the structure-activity relationship.
Lipids 1986;21(4):301-4.
1985: Wolfgang E Berdel; H D Schick; U Fink; A Reichert; K Ulm; J Rastetter
Cytotoxicity of the alkyl-linked lipoidal amine 4-aminomethyl-1-[2,3-(di-n-decyloxy)-n-propyl]-4-phenylpiperidine (CP-46,665) in cells from human tumors and leukemias.
Cancer research 1985;45(3):1206-13.
1983: Wolfgang E Berdel; M Fromm; U Fink; W Pahlke; U Bicker; A Reichert; J Rastetter
Cytotoxicity of thioether-lysophospholipids in leukemias and tumors of human origin.
Cancer research 1983;43(11):5538-43.