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Keiya Ozawa

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Ishiwata Akira; Mimuro Jun; Mizukami Hiroaki; Kashiwakura Yuji; Takano Katsuhiro; Ohmori Tsukasa; Madoiwa Seiji; Ozawa Keiya; Sakata Yoichi
Liver-restricted expression of the canine factor VIII gene facilitates prevention of inhibitor formation in factor VIII-deficient mice.
Ito Tetsuo; Yamamoto Shigekazu; Hayashi Tsukasa; Kodera Mika; Mizukami Hiroaki; Ozawa Keiya; Muramatsu Shin-ichi
A convenient enzyme-linked immunosorbent assay for rapid screening of anti-adeno-associated virus neutralizing antibodies.
Ozawa Keiya
[History, current status, and future prospect of clinical study on myeloid leukemia]

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2009: Ishiwata Akira; Mimuro Jun; Mizukami Hiroaki; Kashiwakura Yuji; Takano Katsuhiro; Ohmori Tsukasa; Madoiwa Seiji; Ozawa Keiya; Sakata Yoichi
Liver-restricted expression of the canine factor VIII gene facilitates prevention of inhibitor formation in factor VIII-deficient mice.
The journal of gene medicine 2009;11(11):1020-9.
2009: Ito Tetsuo; Yamamoto Shigekazu; Hayashi Tsukasa; Kodera Mika; Mizukami Hiroaki; Ozawa Keiya; Muramatsu Shin-ichi
A convenient enzyme-linked immunosorbent assay for rapid screening of anti-adeno-associated virus neutralizing antibodies.
Annals of clinical biochemistry 2009;46(Pt 6):508-10.
2009: Ozawa Keiya
[History, current status, and future prospect of clinical study on myeloid leukemia]
Nippon rinsho. Japanese journal of clinical medicine 2009;67(10):1841-6.
2009: Takahashi Kayoko; Saga Yasushi; Mizukami Hiroyuki; Takei Yuji; Machida Shizuo; Fujiwara Hiroyuki; Ozawa Keiya; Suzuki Mitsuaki
Cetuximab inhibits growth, peritoneal dissemination, and lymph node and lung metastasis of endometrial cancer, and prolongs host survival.
International journal of oncology 2009;35(4):725-9.
2009: Masuda Shigeo; Ageyama Naohide; Shibata Hiroaki; Obara Yoko; Ikeda Tamako; Takeuchi Kengo; Ueda Yasuji; Ozawa Keiya; Hanazono Yutaka
Cotransplantation with MSCs improves engraftment of HSCs after autologous intra-bone marrow transplantation in nonhuman primates.
Experimental hematology 2009;37(10):1250-1257.e1.
2009: Hidaka Tomonori; Shide Kotaro; Shimoda Haruko; Kameda Takurou; Toyama Keiko; Katayose Keiko; Kubuki Youko; Nagata Kenji; Takenaka Katsuto; Akashi Koichi; Okamura Takashi; Niho Yoshiyuki; Mizoguchi Hideaki; Omine Mitsuhiro; Ozawa Keiya; Harada Mine; Shimoda Kazuya
The impact of cytogenetic abnormalities on the prognosis of primary myelofibrosis: a prospective survey of 202 cases in Japan.
European journal of haematology 2009;83(4):328-33.
2009: Sato Keisuke; Date Shiori; Aoyagi Yumi; Kasahara Yoshiyuki; Nawa Akihiko; Mizukami Hiroaki; Hidema Shizu; Ozawa Keiya; Nishimori Katsuhiko
Generation of adeno-associated virus vector enabling functional expression of oxytocin receptor and fluorescence marker genes using the human eIF4G internal ribosome entry site element.
Bioscience, biotechnology, and biochemistry 2009;73(9):2145-8.
2009: Okada Takashi; Nonaka-Sarukawa Mutsuko; Uchibori Ryosuke; Kinoshita Kazue; Hayashita-Kinoh Hiromi; Nitahara-Kasahara Yuko; Takeda Shin'ichi; Ozawa Keiya
Scalable purification of adeno-associated virus serotype 1 (AAV1) and AAV8 vectors, using dual ion-exchange adsorptive membranes.
Human gene therapy 2009;20(9):1013-21.
2009: Sanada Masashi; Suzuki Takahiro; Shih Lee-Yung; Otsu Makoto; Kato Motohiro; Yamazaki Satoshi; Tamura Azusa; Honda Hiroaki; Sakata-Yanagimoto Mamiko; Kumano Keiki; Oda Hideaki; Yamagata Tetsuya; Takita Junko; Gotoh Noriko; Nakazaki Kumi; Kawamata Norihiko; Onodera Masafumi; Nobuyoshi Masaharu; Hayashi Yasuhide; Harada Hiroshi; Kurokawa Mineo; Chiba Shigeru; Mori Hiraku; Ozawa Keiya; Omine Mitsuhiro; Hirai Hisamaru; Nakauchi Hiromitsu; Koeffler H Phillip; Ogawa Seishi
Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.
Nature 2009;460(7257):904-8.
2009: Ozawa Keiya
[Pathogenesis of transfusional iron overload and iron chelation therapy]
[Rinsho ketsueki] The Japanese journal of clinical hematology 2009;50(7):527-31.
2009: Oka Satoko; Nagatsuka Yasuko; Kikuchi Jiro; Yokote Taiji; Hirabayashi Yoshio; Hanafusa Toshiaki; Ozawa Keiya; Muroi Kazuo
Preferential expression of phosphatidylglucoside along neutrophil differentiation pathway.
Leukemia & lymphoma 2009;50(7):1190-7.
2009: Mori Masaki; Nakamoto Shu; Akifuji Youichi; Tanaka Takayuki; Komatsu Norio; Hatake Kiyohiko; Ozawa Keiya
Familial sideroblastic anemia associated with cardiac atrial septal defect.
American journal of hematology 2009;84(7):451-2.
2009: Oka Satoko; Muroi Kazuo; Matsuyama Tomohiro; Sato Kazuya; Ueda Masuzu; Toshima Masaki; Suzuki Takahiro; Ozaki Katsutoshi; Mori Masaki; Takubo Takayuki; Nagai Tadashi; Hanafusa Toshiaki; Ozawa Keiya
Correlation between flow cytometric identification of CD33-positive cells and morphological evaluation of myeloblasts in bone marrow of patients with acute myeloblastic leukemia.
Hematology (Amsterdam, Netherlands) 2009;14(3):133-8.
2009: Uchibori Ryosuke; Okada Takashi; Ito Takayuki; Urabe Masashi; Mizukami Hiroaki; Kume Akihiro; Ozawa Keiya
Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy.
The journal of gene medicine 2009;11(5):373-81.
2009: Hirokawa Makoto; Sawada Ken-ichi; Fujishima Naohito; Kawano Fumio; Kimura Akiro; Watanabe Takashi; Arai Ayako; Matsui Toshimitsu; Nakao Shinji; Urabe Akio; Omine Mitsuhiro; Ozawa Keiya
Acquired pure red cell aplasia associated with malignant lymphomas: a nationwide cohort study in Japan for the PRCA Collaborative Study Group.
American journal of hematology 2009;84(3):144-8.
2009: Nagai Sumimasa; Toshima Masaki; Sato Kazuya; Mori Masaki; Nagai Tadashi; Muroi Kazuo; Ozawa Keiya
Maintenance and preemptive therapy with ganciclovir for cytomegalovirus colitis with extremely high antigenemia in adult T-cell leukemia.
International journal of hematology 2009;89(2):249-50.
2009: Nomoto T; Okada T; Shimazaki K; Yoshioka T; Nonaka-Sarukawa M; Ito T; Takeuchi K; Katsura K-I; Mizukami H; Kume A; Ookawara S; Ikeda U; Katayama Y; Ozawa K
Systemic delivery of IL-10 by an AAV vector prevents vascular remodeling and end-organ damage in stroke-prone spontaneously hypertensive rat.
Gene therapy 2009;16(3):383-91.
2009: Oka Satoko; Muroi Kazuo; Mori Masaki; Matsuyama Tomohiro; Fujiwara Shin-ichiro; Oh Iekuni; Sato Kazuya; Kikuchi Satoru; Ueda Masuzu; Toshima Masaki; Suzuki Takahiro; Ozaki Katsutoshi; Nagai Tadashi; Ozawa Keiya
Prediction of response to imatinib in patients with chronic myelogenous leukemia by flow cytometric analysis of bone marrow blastic cell phenotypes.
Leukemia & lymphoma 2009;50(2):290-3.
2009: Kamesaki Toyomi; Oyamada Takashi; Omine Mitsuhiro; Ozawa Keiya; Kajii Eiji
Cut-off value of red-blood-cell-bound IgG for the diagnosis of Coombs-negative autoimmune hemolytic anemia.
American journal of hematology 2009;84(2):98-101.
2009: Noborio-Hatano K; Kikuchi J; Takatoku M; Shimizu R; Wada T; Ueda M; Nobuyoshi M; Oh I; Sato K; Suzuki T; Ozaki K; Mori M; Nagai T; Muroi K; Kano Y; Furukawa Y; Ozawa K
Bortezomib overcomes cell-adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma.
Oncogene 2009;28(2):231-42.
2009: Kobayashi Hiroyuki; Matsuyama Tomohiro; Ueda Masuzu; Suzuki Takahiro; Ozaki Katsutoshi; Mori Masaki; Nagai Tadashi; Muroi Kazuo; Ozawa Keiya
Predictive factors of response and survival following chemotherapy treatment in acute myeloid leukemia progression from myelodysplastic syndrome.
Internal medicine (Tokyo, Japan) 2009;48(18):1629-33.
2008: Mishima Yuko; Terui Yasuhito; Mishima Yuji; Taniyama Akiko; Kuniyoshi Ryoko; Takizawa Toshihiro; Kimura Shinya; Ozawa Keiya; Hatake Kiyohiko
Autophagy and autophagic cell death are next targets for elimination of the resistance to tyrosine kinase inhibitors.
Cancer science 2008;99(11):2200-8.
2008: Meguro Akiko; Muroi Kazuo; Miyoshi Takuji; Matsuyama Tomohiro; Mori Masaki; Nagai Tadashi; Ozawa Keiya
Sperm cryopreservation in patients with hematologic malignancies.
International journal of hematology 2008;88(3):351-4.
2008: Fujishima Naohito; Sawada Ken-ichi; Hirokawa Makoto; Oshimi Kazuo; Sugimoto Koichi; Matsuda Akira; Teramura Masanao; Karasawa Masamitsu; Arai Ayako; Yonemura Yuji; Nakao Shinji; Urabe Akio; Omine Mitsuhiro; Ozawa Keiya;
Long-term responses and outcomes following immunosuppressive therapy in large granular lymphocyte leukemia-associated pure red cell aplasia: a Nationwide Cohort Study in Japan for the PRCA Collaborative Study Group.
Haematologica 2008;93(10):1555-9.
2008: Fujiwara S-i; Yamashita Y; Nakamura N; Choi Y L; Ueno T; Watanabe H; Kurashina K; Soda M; Enomoto M; Hatanaka H; Takada S; Abe M; Ozawa K; Mano H
High-resolution analysis of chromosome copy number alterations in angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma, unspecified, with single nucleotide polymorphism-typing microarrays.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2008;22(10):1891-8.
2008: Imai Toshimi; Nishimura Yoshioki; Murata Mitsunobu; Saitou Toshinobu; Yamamoto Keiji; Mitsuhashi Takeshi; Shimada Kazuyuki; Satou Kazuya; Matsuyama Tomohiro; Ozawa Keiya
[Intravascular large B-cell lymphoma with left ventricular dysfunction]
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2008;97(7):1666-8.
2008: Miyazawa Keisuke; Ohyashiki Kazuma; Urabe Akio; Hata Tomoko; Nakao Shinji; Ozawa Keiya; Ishikawa Takayuki; Kato Junji; Tatsumi Yoichi; Mori Hiraku; Kondo Midori; Taniguchi Junsuke; Tanii Hiromi; Rojkjaer Lisa; Omine Mitsuhiro
A safety, pharmacokinetic and pharmacodynamic investigation of deferasirox (Exjade, ICL670) in patients with transfusion-dependent anemias and iron-overload: a Phase I study in Japan.
International journal of hematology 2008;88(1):73-81.
2008: Suzuki Takahiro; Tomonaga Masao; Miyazaki Yasushi; Nakao Shinji; Ohyashiki Kazuma; Matsumura Itaru; Kohgo Yutaka; Niitsu Yoshiro; Kojima Seiji; Ozawa Keiya
Japanese epidemiological survey with consensus statement on Japanese guidelines for treatment of iron overload in bone marrow failure syndromes.
International journal of hematology 2008;88(1):30-5.
2008: Yoshida Kozue; Kirito Keita; Yongzhen Hu; Ozawa Keiya; Kaushansky Kenneth; Komatsu Norio
Thrombopoietin (TPO) regulates HIF-1alpha levels through generation of mitochondrial reactive oxygen species.
International journal of hematology 2008;88(1):43-51.
2008: Ozawa Keiya; Sato Kazuya; Oh Iekuni; Ozaki Katsutoshi; Uchibori Ryosuke; Obara Yoko; Kikuchi Yuji; Ito Takayuki; Okada Takashi; Urabe Masashi; Mizukami Hiroaki; Kume Akihiro
Cell and gene therapy using mesenchymal stem cells (MSCs).
Journal of autoimmunity 2008;30(3):121-7.
2008: Nagai Tadashi; Kikuchi Satoru; Ohmine Ken; Miyoshi Takuji; Nakamura Makiko; Kondo Takahito; Furuyama Kazumichi; Komatsu Norio; Ozawa Keiya
Hemin reduces cellular sensitivity to imatinib and anthracyclins via Nrf2.
Journal of cellular biochemistry 2008;104(2):680-91.
2008: Nonaka-Sarukawa Mutsuko; Okada Takashi; Ito Takayuki; Yamamoto Keiji; Yoshioka Toru; Nomoto Tatsuya; Hojo Yukihiro; Shimpo Masahisa; Urabe Masashi; Mizukami Hiroaki; Kume Akihiro; Ikeda Uichi; Shimada Kazuyuki; Ozawa Keiya
Adeno-associated virus vector-mediated systemic interleukin-10 expression ameliorates hypertensive organ damage in Dahl salt-sensitive rats.
The journal of gene medicine 2008;10(4):368-74.
2008: Suzumura Kazuhiro; Hirano Tadamichi; Son Gakuhei; Iimuro Yuji; Mizukami Hiroaki; Ozawa Keiya; Fujimoto Jiro
Adeno-associated virus vector-mediated production of hepatocyte growth factor attenuates liver fibrosis in mice.
Hepatology international 2008;2(1):80-8.
2008: Takei Yuji; Saga Yasushi; Mizukami Hiroaki; Takayama Takeshi; Ohwada Michitaka; Ozawa Keiya; Suzuki Mitsuaki
Overexpression of PTEN in ovarian cancer cells suppresses i.p. dissemination and extends survival in mice.
Molecular cancer therapeutics 2008;7(3):704-11.
2008: Ozawa Keiya
[Pathophysiology, diagnosis and treatment of anemia]
Nippon rinsho. Japanese journal of clinical medicine 2008;66(3):423-8.
2008: Tamai Hayato; Yamaguchi Hiroki; Hamaguchi Hiroyuki; Yagasaki Fumiharu; Bessho Masami; Kobayashi Takeshi; Akiyama Hideki; Sakamaki Hisashi; Takahashi Satoshi; Tojo Arinobu; Ohmine Ken; Ozawa Keiya; Okumura Hirokazu; Nakao Shinji; Arai Ayako; Miura Osamu; Toyota Shigeo; Gomi Seiji; Murai Yoshiro; Usui Noriko; Miyazawa Keisuke; Ohyashiki Kazuma; Takahashi Naoto; Sawada Kenichi; Kato Atsushi; Oshimi Kazuo; Inokuchi Koiti; Dan Kazuo
Clinical features of adult acute leukemia with 11q23 abnormalities in Japan: a co-operative multicenter study.
International journal of hematology 2008;87(2):195-202.
2008: Liu Yuhe; Okada Takashi; Shimazaki Kuniko; Sheykholeslami Kianoush; Nomoto Tatsuya; Muramatsu Shin-Ichi; Mizukami Hiroaki; Kume Akihiro; Xiao Shuifang; Ichimura Keiichi; Ozawa Keiya
Protection against aminoglycoside-induced ototoxicity by regulated AAV vector-mediated GDNF gene transfer into the cochlea.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(3):474-80.
2008: Morimatsu Yukako; Matsubara Shigeki; Hirose Noriko; Ohkuchi Akihide; Izumi Akio; Ozaki Katsutoshi; Ozawa Keiya; Suzuki Mitsuaki
Acute promyelocytic leukemia: an unusual cause showing prolonged disseminated intravascular coagulation after placental abruption.
Archives of gynecology and obstetrics 2008;277(3):267-70.
2008: Iwamoto Michiko; Yamamoto Hironori; Miyata Tomohiko; Sunada Keijiro; Sugano Kentaro; Ozawa Keiya
Leukemic cell infiltration into the large intestine in a patient with acute myelogenous leukemia.
Gastrointestinal endoscopy 2008;67(2):353-4.
2008: Hirokawa Makoto; Sawada Ken-ichi; Fujishima Naohito; Nakao Shinji; Urabe Akio; Dan Kazuo; Fujisawa Shin; Yonemura Yuji; Kawano Fumio; Omine Mitsuhiro; Ozawa Keiya;
Long-term response and outcome following immunosuppressive therapy in thymoma-associated pure red cell aplasia: a nationwide cohort study in Japan by the PRCA collaborative study group.
Haematologica 2008;93(1):27-33.
2008: Akutsu Miyuki; Tsunoda Saburo; Izumi Tohru; Tanaka Masaru; Katano Susumu; Inoue Koichi; Igarashi Seiji; Hirabayashi Kaoru; Furukawa Yusuke; Ohmine Ken; Sato Kazuya; Kobayashi Hiroyuki; Ozawa Keiya; Kirito Keita; Nagashima Takahiro; Teramukai Satoshi; Fukushima Masanori; Kano Yasuhiko
Long-term results of dose-intensive chemotherapy with G-CSF support (TCC-NHL-91) for advanced intermediate-grade non-Hodgkin's lymphoma: a review of 59 consecutive cases treated at a single institute.
Oncology research 2008;17(3):137-49.
2008: Horie M; Ogawa H; Yoshida Y; Yamada K; Hara A; Ozawa K; Matsuda S; Mizota C; Tani M; Yamamoto Y; Yamada M; Nakamura K; Imai K
Inactivation and morphological changes of avian influenza virus by copper ions.
Archives of virology 2008;153(8):1467-72.
2008: Oka Satoko; Muroi Kazuo; Toshima Masaki; Nagai Tadashi; Kanai Nobuyuki; Morita Tatsuo; Ozawa Keiya
Amyloidosis and myelodysplastic syndrome.
Internal medicine (Tokyo, Japan) 2008;47(2):123-4.
2008: Okada Takashi; Ozawa Keiya
Vector-producing tumor-tracking multipotent mesenchymal stromal cells for suicide cancer gene therapy.
Frontiers in bioscience : a journal and virtual library 2008;13():1887-91.
2007: Kobayashi Minoru; Okada Takashi; Murakami Takashi; Ozawa Keiya; Kobayashi Eiji; Morita Tatsuo
Tissue-targeted in vivo gene transfer coupled with histone deacetylase inhibitor depsipeptide (FK228) enhances adenoviral infection in rat renal cancer allograft model systems.
Urology 2007;70(6):1230-6.
2007: Kikuchi Satoru; Nagai Tadashi; Kunitama Masae; Kirito Keita; Ozawa Keiya; Komatsu Norio
Active FKHRL1 overcomes imatinib resistance in chronic myelogenous leukemia-derived cell lines via the production of tumor necrosis factor-related apoptosis-inducing ligand.
Cancer science 2007;98(12):1949-58.
2007: Uchida Mie; Kirito Keita; Endo Hitoshi; Ozawa Keiya; Komatsu Norio
Activation of FKHRL1 plays an important role in protecting erythroid cells from erythropoietin deprivation-induced apoptosis in a human erythropoietin-dependent leukemia cell line, UT-7/EPO.
International journal of hematology 2007;86(4):315-24.
2007: Kikuchi Jiro; Shimizu Rumi; Wada Taeko; Ando Hidenobu; Nakamura Mitsuru; Ozawa Keiya; Furukawa Yusuke
E2F-6 suppresses growth-associated apoptosis of human hematopoietic progenitor cells by counteracting proapoptotic activity of E2F-1.
Stem cells (Dayton, Ohio) 2007;25(10):2439-47.
2007: Ito Takayuki; Okada Takashi; Miyashita Hiroshi; Nomoto Tatsuya; Nonaka-Sarukawa Mutsuko; Uchibori Ryosuke; Maeda Yoshikazu; Urabe Masashi; Mizukami Hiroaki; Kume Akihiro; Takahashi Masafumi; Ikeda Uichi; Shimada Kazuyuki; Ozawa Keiya
Interleukin-10 expression mediated by an adeno-associated virus vector prevents monocrotaline-induced pulmonary arterial hypertension in rats.
Circulation research 2007;101(7):734-41.
2007: Miyoshi Takuji; Nagai Tadashi; Kikuchi Satoru; Ohmine Ken; Nakamura Makiko; Hanafusa Toshiaki; Komatsu Norio; Ozawa Keiya
Cloning and characterization of a human BCR/ABL-positive cell line, K562/RR, resistant to the farnesyltransferase inhibition by tipifarnib.
Experimental hematology 2007;35(9):1358-65.
2007: Ito Takayuki; Okada Takashi; Mimuro Jun; Miyashita Hiroshi; Uchibori Ryosuke; Urabe Masashi; Mizukami Hiroaki; Kume Akihiro; Takahashi Masafumi; Ikeda Uichi; Sakata Yoichi; Shimada Kazuyuki; Ozawa Keiya
Adenoassociated virus-mediated prostacyclin synthase expression prevents pulmonary arterial hypertension in rats.
Hypertension 2007;50(3):531-6.
2007: Kawano-Yamamoto Chizuru; Muroi Kazuo; Mori Masaki; Nagai Tadashi; Ozawa Keiya
Leuprorelin acetate for female patients with newly diagnosed acute leukemia receiving chemotherapy.
International journal of hematology 2007;86(2):199-201.
2007: Tarumoto Takahisa; Imagawa Shigehiko; Kobayashi Makoto; Hirayama Aki; Ozawa Keiya; Nagasawa Toshiro
L-arginine administration reverses anemia associated with renal disease.
International journal of hematology 2007;86(2):126-9.
2007: Mori Masaki; Muroi Kazuo; Matsuyama Tomohiro; Oka Satoko; Ono Yoko; Yamamoto Chizuru; Uesawa Mitsuyo; Okabe Hiroshi; Matsu Haruko; Tatara Raine; Kikuchi Yuji; Fujiwara Shinichiro; Kikuchi Satoru; Sato Kazuya; Ueda Masuzu; Toshima Masaki; Ozaki Katsutoshi; Takatoku Masaaki; Nagai Tadashi; Ozawa Keiya
[Benefits of mycophenolate mofetil for refractory graft-versus-host disease]
[Rinsho ketsueki] The Japanese journal of clinical hematology 2007;48(8):624-31.
2007: Ozawa Keiya
[Development of AAV vector and its application to gene therapy]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2007;52(10 Suppl):1288-93.
2007: Sawada Ken-ichi; Hirokawa Makoto; Fujishima Naohito; Teramura Masanao; Bessho Masami; Dan Kazuo; Tsurumi Hisashi; Nakao Shinji; Urabe Akio; Omine Mitsuhiro; Ozawa Keiya;
Long-term outcome of patients with acquired primary idiopathic pure red cell aplasia receiving cyclosporine A. A nationwide cohort study in Japan for the PRCA Collaborative Study Group.
Haematologica 2007;92(8):1021-8.
2007: Ozaki Katsutoshi; Sato Kazuya; Oh Iekuni; Meguro Akiko; Tatara Raine; Muroi Kazuo; Ozawa Keiya
Mechanisms of immunomodulation by mesenchymal stem cells.
International journal of hematology 2007;86(1):5-7.
2007: Ozawa Keiya
[Gene therapy using AAV]
Uirusu. Journal of virology 2007;57(1):47-55.
2007: Tsunoda Saburo; Kobayashi Hiroyuki; Inoue Koichi; Izumi Tohru; Akutsu Miyuki; Katano Susumu; Ueda Tomoki; Shirai Toshitaka; Masuda Yoshihiro; Ohmine Kenichi; Nagashima Takahiro; Ueda Masuzu; Takagi Syojiro; Muroi Kazuo; Ozawa Keiya; Kano Yasuhiko
[MTX-HOPE (methotrexate, hydrocortisone, vincristine, sobuzoxane, and etoposide) as a low-dose salvage chemotherapy for recurrent or refractory non-Hodgkin's lymphoma]
Gan to kagaku ryoho. Cancer & chemotherapy 2007;34(6):885-9.
2007: Takatoku Masaaki; Uchiyama Takashi; Okamoto Shinichiro; Kanakura Yuzuru; Sawada Kenichi; Tomonaga Masao; Nakao Shinji; Nakahata Tatsutoshi; Harada Mine; Murate Takashi; Ozawa Keiya;
Retrospective nationwide survey of Japanese patients with transfusion-dependent MDS and aplastic anemia highlights the negative impact of iron overload on morbidity/mortality.
European journal of haematology 2007;78(6):487-94.
2007: Fujiwara Shin-Ichiro; Yamashita Yoshihiro; Choi Young Lim; Watanabe Hideki; Kurashina Kentaro; Soda Manabu; Enomoto Munehiro; Hatanaka Hisashi; Takada Shuji; Ozawa Keiya; Mano Hiroyuki
Transforming activity of purinergic receptor P2Y, G protein coupled, 8 revealed by retroviral expression screening.
Leukemia & lymphoma 2007;48(5):978-86.
2007: Shimoda Kazuya; Shide Kotaro; Kamezaki Kenjirou; Okamura Takashi; Harada Naoki; Kinukawa Naoko; Ohyashiki Kazuma; Niho Yoshiyuki; Mizoguchi Hideaki; Omine Mitsuhiro; Ozawa Keiya; Haradaa Mine
The effect of anabolic steroids on anemia in myelofibrosis with myeloid metaplasia: retrospective analysis of 39 patients in Japan.
International journal of hematology 2007;85(4):338-43.
2007: Sanada M; Uike N; Ohyashiki K; Ozawa K; Lili W; Hangaishi A; Kanda Y; Chiba S; Kurokawa M; Omine M; Mitani K; Ogawa S
Unbalanced translocation der(1;7)(q10;p10) defines a unique clinicopathological subgroup of myeloid neoplasms.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(5):992-7.
2007: Liu Yuhe; Okada Takashi; Nomoto Tatsuya; Ke Xiaomei; Kume Akihiro; Ozawa Keiya; Xiao Shuifang
Promoter effects of adeno-associated viral vector for transgene expression in the cochlea in vivo.
Experimental & molecular medicine 2007;39(2):170-5.
2007: Oh I; Ozaki K; Sato K; Meguro A; Tatara R; Hatanaka K; Nagai T; Muroi K; Ozawa K
Interferon-gamma and NF-kappaB mediate nitric oxide production by mesenchymal stromal cells.
Biochemical and biophysical research communications 2007;355(4):956-62.
2007: Fujiwara Shin-Ichiro; Muroi Kazuo; Kikuchi Satoru; Kawano-Yamamoto Chizuru; Matsuyama Tomohiro; Mori Masaki; Nagai Tadashi; Akutsu Miyuki; Ozawa Keiya
Development of streptococcus meningitis and Epstein-Barr virus reactivation after non-T-cell-depleted human leukocyte antigen-haploidentical peripheral blood stem cell transplantation based on feto-maternal microchimerism.
Leukemia & lymphoma 2007;48(3):640-2.
2007: Nakata Masanori; Okada Takashi; Ozawa Keiya; Yada Toshihiko
Resistin induces insulin resistance in pancreatic islets to impair glucose-induced insulin release.
Biochemical and biophysical research communications 2007;353(4):1046-51.
2007: Wang Xiao Tian; Liu Paul Y; Tang Jin Bo; Mizukami Hiroaki; Xin Ke-Qin; Ozawa Keiya; Ushijima Hiroshi
Tendon healing in vitro: adeno-associated virus-2 effectively transduces intrasynovial tenocytes with persistent expression of the transgene, but other serotypes do not.
Plastic and reconstructive surgery 2007;119(1):227-34.
2007: Ideno Junichi; Mizukami Hiroaki; Kakehashi Akihiro; Saito Yuka; Okada Takashi; Urabe Masashi; Kume Akihiro; Kuroki Masatoshi; Kawakami Masanobu; Ishibashi Shun; Ozawa Keiya
Prevention of diabetic retinopathy by intraocular soluble flt-1 gene transfer in a spontaneously diabetic rat model.
International journal of molecular medicine 2007;19(1):75-9.
2007: Takei Yuji; Mizukami Hiroaki; Saga Yasushi; Yoshimura Ichiro; Hasumi Yoko; Takayama Takeshi; Kohno Takahiro; Matsushita Takashi; Okada Takashi; Kume Akihiro; Suzuki Mitsuaki; Ozawa Keiya
Suppression of ovarian cancer by muscle-mediated expression of soluble VEGFR-1/Flt-1 using adeno-associated virus serotype 1-derived vector.
International journal of cancer. Journal international du cancer 2007;120(2):278-84.
2007: Sato Kazuya; Ozaki Katsutoshi; Oh Iekuni; Meguro Akiko; Hatanaka Keiko; Nagai Tadashi; Muroi Kazuo; Ozawa Keiya
Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells.
Blood 2007;109(1):228-34.
2007: Oka Satoko; Muroi Kazuo; Mori Masaki; Matsuyama Tomohiro; Fujiwara Sin-ichiro; Oh Iekuni; Ono Yoko; Kikuchi Satoru; Sato Kazuya; Ueda Masuzu; Toshima Masaki; Ozaki Katsutoshi; Takatoku Masaaki; Nagai Tadashi; Ozawa Keiya
Evaluation of platelet transfusion thresholds in patients with acute myeloblastic leukemia receiving induction chemotherapy.
Internal medicine (Tokyo, Japan) 2007;46(19):1669-70.
2007: Oh I; Ozaki M; Miyazato A; Sato K; Meguro A; Muroi K; Nagai T; Mano H; Ozawa K
Screening of genes responsible for differentiation of mouse mesenchymal stromal cells by DNA micro-array analysis of C3H10T1/2 and C3H10T1/2-derived cell lines.
Cytotherapy 2007;9(1):80-90.
2007: Ito Takayuki; Ozawa Keiya; Shimada Kazuyuki
Current drug targets and future therapy of pulmonary arterial hypertension.
Current medicinal chemistry 2007;14(6):719-33.
2007: Madoiwa Seiji; Someya Tsutomu; Hironaka Mitsugu; Kobayashi Hiroshi; Ohmori Tsukasa; Mimuro Jun; Sugiyama Yukihiko; Morita Tatsuo; Nishimura Yoshioki; Tarumoto Takahisa; Ozawa Keiya; Saito Ken; Sakata Yoichi
Annexin 2 and hemorrhagic disorder in vascular intimal carcinomatosis.
Thrombosis research 2007;119(2):229-40.
2006: Xin Ke-Qin; Mizukami Hiroaki; Urabe Masashi; Toda Yoshihiko; Shinoda Kaori; Yoshida Atsushi; Oomura Kenji; Kojima Yoshitsugu; Ichino Motohide; Klinman Dennis; Ozawa Keiya; Okuda Kenji
Induction of robust immune responses against human immunodeficiency virus is supported by the inherent tropism of adeno-associated virus type 5 for dendritic cells.
Journal of virology 2006;80(24):11899-910.
2006: Mizukami Hiroaki; Ozawa Keiya
[Utility of AAV vectors derived from novel serotypes]
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2006;126(11):1021-8.
2006: Ozaki Katsutoshi; Hishiya Ai; Hatanaka Keiko; Nakajima Hideaki; Wang Gang; Hwu Patrick; Kitamura Toshio; Ozawa Keiya; Leonard Warren J; Nosaka Tetsuya
Overexpression of interleukin 21 induces expansion of hematopoietic progenitor cells.
International journal of hematology 2006;84(3):224-30.
2006: Mizukami Hiroaki; Mimuro Jun; Ogura Tsuyoshi; Okada Takashi; Urabe Masashi; Kume Akihiro; Sakata Yoichi; Ozawa Keiya
Adipose tissue as a novel target for in vivo gene transfer by adeno-associated viral vectors.
Human gene therapy 2006;17(9):921-8.
2006: Meguro-Hashimoto Akiko; Takatoku Masaaki; Ohmine Ken; Toshima Masaki; Mori Masaki; Nagai Tadashi; Muroi Kazuo; Ozawa Keiya
The usefulness of magnetic resonance imaging (MRI) for disseminated trichosporosis of the gastrocnemius muscles.
The Journal of infection 2006;53(3):e135-8.
2006: Nagashima Takahiro; Muroi Kazuo; Kawano-Yamamoto Chizuru; Miyoshi Takuji; Tatara Raine; Meguro Akiko; Fujiwara Shin-Ichiro; Obara Yoko; Oh Iekuni; Kikuchi Satoru; Sato Kazuya; Matsuyama Tomohiro; Toshima Masaki; Ohmine Ken; Ozaki Katsutoshi; Takatoku Masaaki; Mori Masaki; Nagai Tadashi; Ozawa Keiya
Pleocytosis after hemopoietic stem cell transplantation.
Leukemia & lymphoma 2006;47(8):1613-7.
2006: Ogura Tsuyoshi; Mizukami Hiroaki; Mimuro Jun; Madoiwa Seiji; Okada Takashi; Matsushita Takashi; Urabe Masashi; Kume Akihiro; Hamada Hiromi; Yoshikawa Hiroyuki; Sakata Yoichi; Ozawa Keiya
Utility of intraperitoneal administration as a route of AAV serotype 5 vector-mediated neonatal gene transfer.
The journal of gene medicine 2006;8(8):990-7.
2006: Ohmori Tsukasa; Mimuro Jun; Takano Katsuhiro; Madoiwa Seiji; Kashiwakura Yuji; Ishiwata Akira; Niimura Masanori; Mitomo Katsuyuki; Tabata Toshiaki; Hasegawa Mamoru; Ozawa Keiya; Sakata Yoichi
Efficient expression of a transgene in platelets using simian immunodeficiency virus-based vector harboring glycoprotein Ibalpha promoter: in vivo model for platelet-targeting gene therapy.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(9):1522-4.
2006: Kawano-Yamamoto Chizuru; Muroi Kazuo; Nagatsuka Yasuko; Higuchi Masato; Kikuchi Satoru; Nagai Tadashi; Hakomori Sen-Itiroh; Ozawa Keiya
Establishment and characterization of a new erythroblastic leukemia cell line, EEB: phosphatidylglucoside-mediated erythroid differentiation and apoptosis.
Leukemia research 2006;30(7):829-39.
2006: Ageyama Naohide; Hanazono Yutaka; Shibata Hiroaki; Ono Fumiko; Nagashima Takeyuki; Ueda Yasuji; Yoshikawa Yasuhiro; Hasegawa Mamoru; Ozawa Keiya; Terao Keiji
Prevention of immune responses to human erythropoietin in cynomolgus monkeys (Macaca fascicularis).
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2006;68(5):507-10.
2006: Miyakoshi Shigesaburo; Kami Masahiro; Yuji Koichiro; Matsumura Tomoko; Takatoku Masaaki; Sasaki Makoto; Narimatsu Hiroto; Fujii Takeshi; Kawabata Masateru; Taniguchi Shuichi; Ozawa Keiya; Oshimi Kazuo
Severe pulmonary complications in Japanese patients after bortezomib treatment for refractory multiple myeloma.
Blood 2006;107(9):3492-4.
2006: Machida Yoko; Okada Takashi; Kurosawa Masaru; Oyama Fumitaka; Ozawa Keiya; Nukina Nobuyuki
rAAV-mediated shRNA ameliorated neuropathology in Huntington disease model mouse.
Biochemical and biophysical research communications 2006;343(1):190-7.
2006: Urabe Masashi; Xin Ke-Qin; Obara Yoko; Nakakura Takayo; Mizukami Hiroaki; Kume Akihiro; Okuda Kenji; Ozawa Keiya
Removal of empty capsids from type 1 adeno-associated virus vector stocks by anion-exchange chromatography potentiates transgene expression.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(4):823-8.
2006: Okada Takashi; Uchibori Ryosuke; Iwata-Okada Mayumi; Takahashi Masafumi; Nomoto Tatsuya; Nonaka-Sarukawa Mutsuko; Ito Takayuki; Liu Yuhe; Mizukami Hiroaki; Kume Akihiro; Kobayashi Eiji; Ozawa Keiya
A histone deacetylase inhibitor enhances recombinant adeno-associated virus-mediated gene expression in tumor cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(4):738-46.
2006: Urabe Masashi; Nakakura Takayo; Xin Ke-Qin; Obara Yoko; Mizukami Hiroaki; Kume Akihiro; Kotin Robert M; Ozawa Keiya
Scalable generation of high-titer recombinant adeno-associated virus type 5 in insect cells.
Journal of virology 2006;80(4):1874-85.
2006: Li Xiao-Gang; Okada Takashi; Kodera Mika; Nara Yuko; Takino Naomi; Muramatsu Chieko; Ikeguchi Kunihiko; Urano Fumi; Ichinose Hiroshi; Metzger Daniel; Chambon Pierre; Nakano Imaharu; Ozawa Keiya; Muramatsu Shin-Ichi
Viral-mediated temporally controlled dopamine production in a rat model of Parkinson disease.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(1):160-6.
2006: Uesawa Mitsuyo; Sato Kazuya; Ozaki Katsutoshi; Nagai Tadashi; Muroi Kazuo; Ozawa Keiya
Bone marrow metastasis of malignant melanoma.
Internal medicine (Tokyo, Japan) 2006;45(5):341.
2006: Sutheesophon Krittaya; Kobayashi Yukiko; Takatoku Masa-aki; Ozawa Keiya; Kano Yasuhiko; Ishii Hideshi; Furukawa Yusuke
Histone deacetylase inhibitor depsipeptide (FK228) induces apoptosis in leukemic cells by facilitating mitochondrial translocation of Bax, which is enhanced by the proteasome inhibitor bortezomib.
Acta haematologica 2006;115(1-2):78-90.
2006: Ishiwata Akira; Mimuro Jun; Kashiwakura Yuji; Niimura Masanori; Takano Katsuhiro; Ohmori Tsukasa; Madoiwa Seiji; Mizukami Hiroaki; Okada Takashi; Naka Hiroyuki; Yoshioka Akira; Ozawa Keiya; Sakata Yoichi
Phenotype correction of hemophilia A mice with adeno-associated virus vectors carrying the B domain-deleted canine factor VIII gene.
Thrombosis research 2006;118(5):627-35.
2005: Iwata Nobuhisa; Saido Takaomi C; Mizukami Hiroaki; Ozawa Keiya
[Experimental gene therapy for Alzheimer's disease--animal models]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 12():691-8.
2005: Ozawa Keiya
[Methods of gene transfer]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 12():481-5.
2005: Hiraide Atsuo; Yokoo Naoki; Xin Ke-Qin; Okuda Kenji; Mizukami Hiroaki; Ozawa Keiya; Saito Tomoyuki
Repair of articular cartilage defect by intraarticular administration of basic fibroblast growth factor gene, using adeno-associated virus vector.
Human gene therapy 2005;16(12):1413-21.
2005: Fujiwara Shin-ichiro; Yamashita Yoshihiro; Choi Young Lim; Wada Tomoaki; Kaneda Ruri; Takada Shuji; Maruyama Yukio; Ozawa Keiya; Mano Hiroyuki
Transforming activity of the lymphotoxin-beta receptor revealed by expression screening.
Biochemical and biophysical research communications 2005;338(2):1256-62.
2005: Ageyama Naohide; Hanazono Yutaka; Shibata Hiroaki; Ono Fumiko; Ogawa Hiromi; Nagashima Takeyuki; Ueda Yasuji; Yoshikawa Yasuhiro; Hasegawa Mamoru; Ozawa Keiya; Terao Keiji
Safe and efficient collection of cytokine-mobilized peripheral blood cells from cynomolgus monkeys (Macaca fascicularis) with human newborn-equivalent body weights.
Experimental animals / Japanese Association for Laboratory Animal Science 2005;54(5):421-8.
2005: Nagai Tadashi; Komatsu Norio; Sakata Yoichi; Miura Yasusada; Ozawa Keiya
Iron deficiency anemia with marked thrombocytosis complicated by central retinal vein occlusion.
Internal medicine (Tokyo, Japan) 2005;44(10):1090-2.
2005: Okada Takashi; Nomoto Tatsuya; Yoshioka Toru; Nonaka-Sarukawa Mutsuko; Ito Takayuki; Ogura Tsuyoshi; Iwata-Okada Mayumi; Uchibori Ryosuke; Shimazaki Kuniko; Mizukami Hiroaki; Kume Akihiro; Ozawa Keiya
Large-scale production of recombinant viruses by use of a large culture vessel with active gassing.
Human gene therapy 2005;16(10):1212-8.
2005: Liu Yuhe; Okada Takashi; Sheykholeslami Kianoush; Shimazaki Kuniko; Nomoto Tatsuya; Muramatsu Shin-Ichi; Kanazawa Takeharu; Takeuchi Koichi; Ajalli Rahim; Mizukami Hiroaki; Kume Akihiro; Ichimura Keiichi; Ozawa Keiya
Specific and efficient transduction of Cochlear inner hair cells with recombinant adeno-associated virus type 3 vector.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(4):725-33.
2005: Ishii Hideshi; Inageta Taeko; Mimori Koshi; Saito Toshiyuki; Sasaki Hiroki; Isobe Masaharu; Mori Masaki; Croce Carlo M; Huebner Kay; Ozawa Keiya; Furukawa Yusuke
Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(27):9655-60.
2005: Fujishiro Jun; Takeda Shin-ichi; Takeno Yuichi; Takeuchi Koichi; Ogata Yukiyo; Takahashi Masafumi; Hakamata Yoji; Kaneko Takashi; Murakami Takashi; Okada Takashi; Ozawa Keiya; Hashizume Kohei; Kobayashi Eiji
Gene transfer to the rat kidney in vivo and ex vivo using an adenovirus vector: factors influencing transgene expression.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2005;20(7):1385-91.
2005: Maruyama Masahiro; Higuchi Makoto; Takaki Yoshie; Matsuba Yukio; Tanji Haruko; Nemoto Miyako; Tomita Naoki; Matsui Toshifumi; Iwata Nobuhisa; Mizukami Hiroaki; Muramatsu Shin-ichi; Ozawa Keiya; Saido Takaomi C; Arai Hiroyuki; Sasaki Hidetada
Cerebrospinal fluid neprilysin is reduced in prodromal Alzheimer's disease.
Annals of neurology 2005;57(6):832-42.
2005: Miyoshi Takuji; Nagai Tadashi; Ohmine Ken; Nakamura Makiko; Kano Yasuhiko; Muroi Kazuo; Komatsu Norio; Ozawa Keiya
Relative importance of apoptosis and cell cycle blockage in the synergistic effect of combined R115777 and imatinib treatment in BCR/ABL-positive cell lines.
Biochemical pharmacology 2005;69(11):1585-94.
2005: Inukai Takeshi; Inaba Toshiya; Dang Jinjun; Kuribara Ryoko; Ozawa Keiya; Miyajima Atsushi; Wu Wenshu; Look A Thomas; Arinobu Yojiro; Iwasaki Hiromi; Akashi Koichi; Kagami Keiko; Goi Kumiko; Sugita Kanji; Nakazawa Shinpei
TEF, an antiapoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by down-regulating expression of the common beta chain of cytokine receptors.
Blood 2005;105(11):4437-44.
2005: Muramatsu Shin-ichi; Tsukada Hideo; Nakano Imaharu; Ozawa Keiya
Gene therapy for Parkinson's disease using recombinant adeno-associated viral vectors.
Expert opinion on biological therapy 2005;5(5):663-71.
2005: Sato Kazuya; Izumi Tohru; Toshima Masaki; Nagai Tadashi; Muroi Kazuo; Komatsu Norio; Ozawa Keiya
Retropharyngeal abscess due to methicillin-resistant Staphylococcus aureus in a case of acute myeloid leukemia.
Internal medicine (Tokyo, Japan) 2005;44(4):346-9.
2005: Inoue Hirokazu; Ohsawa Ichiro; Murakami Takashi; Kimura Atsushi; Hakamata Yoji; Sato Yuki; Kaneko Takashi; Takahashi Masafumi; Okada Takashi; Ozawa Keiya; Francis Jeremy; Leone Paola; Kobayashi Eiji
Development of new inbred transgenic strains of rats with LacZ or GFP.
Biochemical and biophysical research communications 2005;329(1):288-95.
2005: Yoshioka Toru; Ageyama Naohide; Shibata Hiroaki; Yasu Takanori; Misawa Yoshio; Takeuchi Koichi; Matsui Keiji; Yamamoto Keiji; Terao Keiji; Shimada Kazuyuki; Ikeda Uichi; Ozawa Keiya; Hanazono Yutaka
Repair of infarcted myocardium mediated by transplanted bone marrow-derived CD34+ stem cells in a nonhuman primate model.
Stem cells (Dayton, Ohio) 2005;23(3):355-64.
2005: Nagashima Takahiro; Muroi Kazuo; Kawano-Yamamoto Chizuru; Miyoshi Takuji; Ohmine Ken; Toshima Masaki; Miyazato Akira; Takatoku Masaaki; Nagai Tadashi; Mori Masaki; Komatsu Norio; Ozawa Keiya
Autologous gamete cryopreservation before hemopoietic stem cell transplantation.
Medical science monitor : international medical journal of experimental and clinical research 2005;11(3):CR91-4.
2005: Sasaki K; Inoue M; Shibata H; Ueda Y; Muramatsu S-I; Okada T; Hasegawa M; Ozawa K; Hanazono Y
Efficient and stable Sendai virus-mediated gene transfer into primate embryonic stem cells with pluripotency preserved.
Gene therapy 2005;12(3):203-10.
2005: Sasaki Kyoko; Nagao Yoshikazu; Kitano Yoshihiro; Hasegawa Hideaki; Shibata Hiroaki; Takatoku Masaaki; Hayashi Satoshi; Ozawa Keiya; Hanazono Yutaka
Hematopoietic microchimerism in sheep after in utero transplantation of cultured cynomolgus embryonic stem cells.
Transplantation 2005;79(1):32-7.
2005: Yokoo Naoki; Saito Tomoyuki; Uesugi Masaaki; Kobayashi Naomi; Xin Ke-Qin; Okuda Kenji; Mizukami Hiroaki; Ozawa Keiya; Koshino Tomihisa
Repair of articular cartilage defect by autologous transplantation of basic fibroblast growth factor gene-transduced chondrocytes with adeno-associated virus vector.
Arthritis and rheumatism 2005;52(1):164-70.
2005: Takei Yuji; Mizukami Hiroaki; Saga Yasushi; Kobayashi Hiroshi; Suzuki Mika; Matsushita Takashi; Ozawa Keiya; Suzuki Mitsuaki
Overexpression of a hybrid gene consisting of the amino-terminal fragment of urokinase and carboxyl-terminal domain of bikunin suppresses invasion and migration of human ovarian cancer cells in vitro.
International journal of cancer. Journal international du cancer 2005;113(1):54-8.
2004: Sato Kazuya; Nagai Tadashi; Muroi Kazuo; Komatsu Norio; Ozawa Keiya
[Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura--the associateion between the activity of Helicobacter pylori and platelet recovery]
[Rinsho ketsueki] The Japanese journal of clinical hematology 2004;45(12):1252-4.
2004: Yoshioka T; Okada T; Maeda Y; Ikeda U; Shimpo M; Nomoto T; Takeuchi K; Nonaka-Sarukawa M; Ito T; Takahashi M; Matsushita T; Mizukami H; Hanazono Y; Kume A; Ookawara S; Kawano M; Ishibashi S; Shimada K; Ozawa K
Adeno-associated virus vector-mediated interleukin-10 gene transfer inhibits atherosclerosis in apolipoprotein E-deficient mice.
Gene therapy 2004;11(24):1772-9.
2004: Sato Kazuya; Mori Masaki; Meguro Akiko; Miyoshi Takuji; Nagai Tadashi; Muroi Kazuo; Komatsu Norio; Ozawa Keiya
[Minor bcr/abl positive acute lymphoblastic leukemia preceded by knee joint pain due to bone marrow necrosis]
[Rinsho ketsueki] The Japanese journal of clinical hematology 2004;45(11):1203-7.
2004: Kikuchi Satoru; Muroi Kazuo; Takahashi Satoko; Kawano-Yamamoto Chizuru; Takatoku Masaaki; Miyazato Akira; Nagai Tadashi; Mori Masaki; Komatsu Norio; Ozawa Keiya
Severe hepatitis and complete molecular response caused by imatinib mesylate: possible association of its serum concentration with clinical outcomes.
Leukemia & lymphoma 2004;45(11):2349-51.
2004: Obara Yoko; Nagai Tadashi; Mori Masaki; Ohmine Ken; Toshima Masaki; Komatsu Norio; Ozawa Keiya
[Pseudomonas sepsis with ecthyma gangrenosum in an acute myeloid leukemia patient]
[Rinsho ketsueki] The Japanese journal of clinical hematology 2004;45(10):1138-40.
2004: Kikuchi Jiro; Mimuro Jun; Ogata Kyoichi; Tabata Toshiaki; Ueda Yasuji; Ishiwata Akira; Kimura Kouzoh; Takano Katsuhiro; Madoiwa Seiji; Mizukami Hiroaki; Hanazono Yutaka; Kume Akihiro; Hasegawa Mamoru; Ozawa Keiya; Sakata Yoichi
Sustained transgene expression by human cord blood derived CD34+ cells transduced with simian immunodeficiency virus agmTYO1-based vectors carrying the human coagulation factor VIII gene in NOD/SCID mice.
The journal of gene medicine 2004;6(10):1049-60.
2004: Takatoku Masaaki; Muroi Kazuo; Kawano-Yamamoto Chizuru; Nagai Tadashi; Komatsu Norio; Ozawa Keiya
Involvement of the esophagus and stomach as a first manifestation of varicella zoster virus infection after allogeneic bone marrow transplantation.
Internal medicine (Tokyo, Japan) 2004;43(9):861-4.
2004: Tsutsumi Chizuko; Ueda Masuzu; Miyazaki Yasushi; Yamashita Yoshihiro; Choi Young Lim; Ota Jun; Kaneda Ruri; Koinuma Koji; Fujiwara Shin-ichiro; Kisanuki Hiroyuki; Ishikawa Madoka; Ozawa Keiya; Tomonaga Masao; Mano Hiroyuki
DNA microarray analysis of dysplastic morphology associated with acute myeloid leukemia.
Experimental hematology 2004;32(9):828-35.
2004: Ueda Kyoji; Hanazono Yutaka; Shibata Hiroaki; Ageyama Naohide; Ueda Yasuji; Ogata Satoko; Tabata Toshiaki; Nagashima Takeyuki; Takatoku Masaaki; Kume Akihiko; Ikehara Susumu; Taniwaki Masafumi; Terao Keiji; Hasegawa Mamoru; Ozawa Keiya
High-level in vivo gene marking after gene-modified autologous hematopoietic stem cell transplantation without marrow conditioning in nonhuman primates.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(3):469-77.
2004: Kanazawa Takeharu; Mizukami Hiroaki; Nishino Hiroshi; Okada Takashi; Hanazono Yutaka; Kume Akihiro; Kitamura Ken; Ichimura Keiichi; Ozawa Keiya
Topoisomerase inhibitors enhance the cytocidal effect of AAV-HSVtk/ganciclovir on head and neck cancer cells.
International journal of oncology 2004;25(3):729-35.
2004: Muroi Kazuo; Kawano-Yamamoto Chizuru; Nagashima Takahiro; Mori Masaki; Ozawa Keiya; Matsui Keiji; Murakami Yoshiaki; Ikeda Uichi
Analysis of hematopoietic progenitors in bone marrow from patients with peripheral artery disease.
Leukemia research 2004;28(9):999-1000.
2004: Hara T; Kume A; Hanazono Y; Mizukami H; Okada T; Tsurumi H; Moriwaki H; Ueda Y; Hasegawa M; Ozawa K
Expansion of genetically corrected neutrophils in chronic granulomatous disease mice by cotransferring a therapeutic gene and a selective amplifier gene.
Gene therapy 2004;11(18):1370-7.
2004: Matsushita Takashi; Okada Takashi; Inaba Toshiya; Mizukami Hiroaki; Ozawa Keiya; Colosi Peter
The adenovirus E1A and E1B19K genes provide a helper function for transfection-based adeno-associated virus vector production.
The Journal of general virology 2004;85(Pt 8):2209-14.
2004: Kuribara Ryoko; Honda Hiroaki; Matsui Hirotaka; Shinjyo Tetsuharu; Inukai Takeshi; Sugita Kanji; Nakazawa Shinpei; Hirai Hisamaru; Ozawa Keiya; Inaba Toshiya
Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors.
Molecular and cellular biology 2004;24(14):6172-83.
2004: Mochizuki S; Mizukami H; Ogura T; Kure S; Ichinohe A; Kojima K; Matsubara Y; Kobayahi E; Okada T; Hoshika A; Ozawa K; Kume A
Long-term correction of hyperphenylalaninemia by AAV-mediated gene transfer leads to behavioral recovery in phenylketonuria mice.
Gene therapy 2004;11(13):1081-6.
2004: Ozawa Keiya
[Development and application of gene therapy technologies]
Uirusu. Journal of virology 2004;54(1):49-57.
2004: Toyo-Oka Teruhiko; Kawada Tomie; Nakata Jumi; Xie Han; Urabe Masashi; Masui Fujiko; Ebisawa Takashi; Tezuka Asaki; Iwasawa Kuniaki; Nakajima Toshiaki; Uehara Yoshio; Kumagai Hiroyuki; Kostin Sawa; Schaper Jutta; Nakazawa Mikio; Ozawa Keiya
Translocation and cleavage of myocardial dystrophin as a common pathway to advanced heart failure: a scheme for the progression of cardiac dysfunction.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(19):7381-5.
2004: Mizukami Hiroaki; Okada Takashi; Ogasawara Yoji; Matsushita Takashi; Urabe Masashi; Kume Akihiro; Ozawa Keiya
Separate control of Rep and Cap expression using mutant and wild-type loxP sequences and improved packaging system for adeno-associated virus vector production.
Molecular biotechnology 2004;27(1):7-14.
2004: Tarumoto Takahisa; Nagai Tadashi; Ohmine Ken; Miyoshi Takuji; Nakamura Makiko; Kondo Takahito; Mitsugi Kenji; Nakano Syuji; Muroi Kazuo; Komatsu Norio; Ozawa Keiya
Ascorbic acid restores sensitivity to imatinib via suppression of Nrf2-dependent gene expression in the imatinib-resistant cell line.
Experimental hematology 2004;32(4):375-81.
2004: Okada Takashi; Caplen Natasha J; Ramsey W Jay; Onodera Masafumi; Shimazaki Kuniko; Nomoto Tatsuya; Ajalli Rahim; Wildner Oliver; Morris John; Kume Akihiro; Hamada Hirofumi; Blaese R Michael; Ozawa Keiya
In situ generation of pseudotyped retroviral progeny by adenovirus-mediated transduction of tumor cells enhances the killing effect of HSV-tk suicide gene therapy in vitro and in vivo.
The journal of gene medicine 2004;6(3):288-99.
2004: Takatoku Masaaki; Noborio-Hatano Kaoru; Takahashi Satoko; Kikuchi Satoru; Mori Masaki; Muroi Kazuo; Komatsu Norio; Ozawa Keiya
[Treatment with a proteasome inhibitor, bortezomib, for thalidomide-resistant multiple myeloma]
[Rinsho ketsueki] The Japanese journal of clinical hematology 2004;45(2):144-8.
2004: Tsurumi Hisashi; Yamada Toshiki; Sawada Michio; Kasahara Senji; Kanemura Nobuhiro; Kojima Yasushi; Fukuno Kenji; Hara Takeshi; Saio Masanao; Takahashi Takeshi; Oyama Masami; Ozawa Keiya; Takami Tsuyoshi; Moriwaki Hisataka
Biweekly CHOP or THP-COP regimens in the treatment of newly diagnosed aggressive non-Hodgkin's lymphoma. A comparison of doxorubicin and pirarubicin: a randomized phase II study.
Journal of cancer research and clinical oncology 2004;130(2):107-13.
2004: Nagashima Takahiro; Muroi Kazuo; Kawano-Yamamoto Chizuru; Komatsu Norio; Ozawa Keiya
Paraproteinemia after hematopoietic stem cell transplantation.
Leukemia & lymphoma 2004;45(1):135-7.
2004: Iwata Nobuhisa; Mizukami Hiroaki; Shirotani Keiro; Takaki Yoshie; Muramatsu Shin-ichi; Lu Bao; Gerard Norma P; Gerard Craig; Ozawa Keiya; Saido Takaomi C
Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(4):991-8.
2004: Nagashima Takeyuki; Ueda Yasuji; Hanazono Yutaka; Kume Akihiro; Shibata Hiroaki; Ageyama Naohide; Terao Keiji; Ozawa Keiya; Hasegawa Mamoru
In vivo expansion of gene-modified hematopoietic cells by a novel selective amplifier gene utilizing the erythropoietin receptor as a molecular switch.
The journal of gene medicine 2004;6(1):22-31.
2004: Uchida Mie; Watanabe Tomoko; Kunitama Masae; Mori Masaki; Kikuchi Satoru; Yoshida Kozue; Kirito Keita; Nagai Tadashi; Ozawa Keiya; Komatsu Norio
Erythropoietin overcomes imatinib-induced apoptosis and induces erythroid differentiation in TF-1/bcr-abl cells.
Stem cells (Dayton, Ohio) 2004;22(4):609-16.
2004: Takeda Shin-ichi; Takahashi Masafumi; Mizukami Hiroaki; Kobayashi Eiji; Takeuchi Koichi; Hakamata Yoji; Kaneko Takashi; Yamamoto Hisashi; Ito Chiharu; Ozawa Keiya; Ishibashi Kenichi; Matsuzaki Toshiyuki; Takata Kuniaki; Asano Yasushi; Kusano Eiji
Successful gene transfer using adeno-associated virus vectors into the kidney: comparison among adeno-associated virus serotype 1-5 vectors in vitro and in vivo.
Nephron. Experimental nephrology 2004;96(4):e119-26.
2003: Ozawa Keiya
[Gene therapy using AAV (adeno-associated virus) vectors]
Uirusu. Journal of virology 2003;53(2):163-70.
2003: Ideno Junichi; Mizukami Hiroaki; Honda Kazufumi; Okada Takashi; Hanazono Yutaka; Kume Akihiro; Saito Toshikazu; Ishibashi Shun; Ozawa Keiya
Persistent phenotypic correction of central diabetes insipidus using adeno-associated virus vector expressing arginine-vasopressin in Brattleboro rats.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(6):895-902.
2003: Ozawa Keiya
[AAV vector-mediated gene transfer and its application to the nervous system]
Rinsho shinkeigaku = Clinical neurology 2003;43(11):835-8.
2003: Ishii Hideshi; Ozawa Keiya; Furukawa Yusuke
Alteration of the fragile histidine triad gene early in carcinogenesis: an update.
Journal of experimental therapeutics & oncology 2003;3(6):291-6.
2003: Ishii Hideshi; Vecchione Andrea; Furukawa Yutaka; Sutheesophon Krittaya; Han Shuang-Yin; Druck Teresa; Kuroki Tamotsu; Trapasso Francesco; Nishimura Miki; Saito Yasushi; Ozawa Keiya; Croce Carlo M; Huebner Kay; Furukawa Yusuke
Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies.
Molecular cancer research : MCR 2003;1(13):940-7.
2003: Itoh Akira; Okada Takashi; Mizuguchi Hiroyuki; Hayakawa Takao; Mizukami Hiroaki; Kume Akihiro; Takatoku Masaaki; Komatsu Norio; Hanazono Yutaka; Ozawa Keiya
A soluble CAR-SCF fusion protein improves adenoviral vector-mediated gene transfer to c-Kit-positive hematopoietic cells.
The journal of gene medicine 2003;5(11):929-40.
2003: Nagata Mihoko; Takahashi Masafumi; Muramatsu Shin-Ichi; Ueda Yasuji; Hanazono Yutaka; Takeuchi Koichi; Okada Koji; Suzuki Yutaka; Kondo Yasushi; Suemori Masafumi; Ikeda Uichi; Nakano Imaharu; Kobayashi Eiji; Hasegawa Mamoru; Ozawa Keiya; Nakatsuji Norio; Shimada Kazuyuki
Efficient gene transfer of a simian immuno-deficiency viral vector into cardiomyocytes derived from primate embryonic stem cells.
The journal of gene medicine 2003;5(11):921-8.
2003: Asano Takayuki; Ageyama Naohide; Takeuchi Koichi; Momoeda Mikio; Kitano Yoshihiro; Sasaki Kyoko; Ueda Yasuji; Suzuki Yutaka; Kondo Yasushi; Torii Ryuzo; Hasegawa Mamoru; Ookawara Shigeo; Harii Kiyonori; Terao Keiji; Ozawa Keiya; Hanazono Yutaka
Engraftment and tumor formation after allogeneic in utero transplantation of primate embryonic stem cells.
Transplantation 2003;76(7):1061-7.
2003: Ueda Masuzu; Ota Jun; Yamashita Yoshihiro; Choi Young Lim; Ohki Ruri; Wada Tomoaki; Koinuma Koji; Kano Yasuhiko; Ozawa Keiya; Mano Hiroyuki
DNA microarray analysis of stage progression mechanism in myelodysplastic syndrome.
British journal of haematology 2003;123(2):288-96.
2003: Oshima Y; Ueda M; Yamashita Y; Choi Y L; Ota J; Ueno S; Ohki R; Koinuma K; Wada T; Ozawa K; Fujimura A; Mano H
DNA microarray analysis of hematopoietic stem cell-like fractions from individuals with the M2 subtype of acute myeloid leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(10):1990-7.
2003: Saga Yasushi; Mizukami Hiroaki; Takei Yuji; Ozawa Keiya; Suzuki Mitsuaki
Suppression of cell migration in ovarian cancer cells mediated by PTEN overexpression.
International journal of oncology 2003;23(4):1109-13.
2003: Miyoshi Takuji; Kawano-Yamamoto Chizuru; Nagashima Takahiro; Nagai Tadashi; Komatsu Norio; Muroi Kazuo; Ozawa Keiya
[Successful treatment of refractory acute GVHD with mycophenolate mofetil after peripheral blood stem cell transplantation from the patient's one locus-mismatched mother]
[Rinsho ketsueki] The Japanese journal of clinical hematology 2003;44(9):968-70.
2003: Shibata Hiroaki; Hanazono Yutaka; Ageyama Naohide; Nagashima Takeyuki; Ueda Yasuji; Hasegawa Mamoru; Ozawa Keiya; Yoshikawa Yasuhiro; Terao Keiji
Collection and analysis of hematopoietic progenitor cells from cynomolgus macaques (Macaca fascicularis): assessment of cross-reacting monoclonal antibodies.
American journal of primatology 2003;61(1):3-12.
2003: Saga Yasushi; Suzuki Mitsuaki; Mizukami Hiroaki; Kohno Takahiro; Takei Yuji; Fukushima Masakazu; Ozawa Keiya
Overexpression of thymidylate synthase mediates desensitization for 5-fluorouracil of tumor cells.
International journal of cancer. Journal international du cancer 2003;106(3):324-6.
2003: Kohno Takahiro; Mizukami Hiroaki; Suzuki Mitsuaki; Saga Yasushi; Takei Yuji; Shimpo Masahisa; Matsushita Takashi; Okada Takashi; Hanazono Yutaka; Kume Akihiro; Sato Ikuo; Ozawa Keiya
Interleukin-10-mediated inhibition of angiogenesis and tumor growth in mice bearing VEGF-producing ovarian cancer.
Cancer research 2003;63(16):5091-4.
2003: Urabe Masashi; Kogure Katsuhiro; Kume Akihiro; Sato Yuko; Tobita Kiyotake; Ozawa Keiya
Positive and negative effects of adeno-associated virus Rep on AAVS1-targeted integration.
The Journal of general virology 2003;84(Pt 8):2127-32.
2003: Kametaka Minako; Kume Akihiro; Okada Takashi; Mizukami Hiroaki; Hanazono Yutaka; Ozawa Keiya
Reduction of CTLL-2 cytotoxicity by induction of apoptosis with a Fas-estrogen receptor chimera.
Cancer science 2003;94(7):639-43.
2003: Nagai Tadashi; Tarumoto Takahisa; Miyoshi Takuji; Ohmine Ken; Muroi Kazuo; Komatsu Norio; Sassa Shigeru; Ozawa Keiya
Oxidative stress is involved in hydroxyurea-induced erythroid differentiation.
British journal of haematology 2003;121(4):657-61.
2003: Xin Ke-Qin; Ooki Takaaki; Jounai Nao; Mizukami Hiroaki; Hamajima Kenji; Kojima Yoshitsugu; Ohba Kenji; Toda Yoshihiko; Hirai Syu-Ichi; Klinman Dennis M; Ozawa Keiya; Okuda Kenji
A DNA vaccine containing inverted terminal repeats from adeno-associated virus increases immunity to HIV.
The journal of gene medicine 2003;5(5):438-45.
2003: Ogata Yukiyo; Takahashi Masafumi; Ueno Shuichi; Takeuchi Koichi; Okada Takashi; Mano Hiroyuki; Ookawara Shigeo; Ozawa Keiya; Berk Bradford C; Ikeda Uichi; Shimada Kazuyuki; Kobayashi Eiji
Antiapoptotic effect of endothelin-1 in rat cardiomyocytes in vitro.
Hypertension 2003;41(5):1156-63.
2003: Mori Masaki; Uchida Mie; Watanabe Tomoko; Kirito Keita; Hatake Kiyohiko; Ozawa Keiya; Komatsu Norio
Activation of extracellular signal-regulated kinases ERK1 and ERK2 induces Bcl-xL up-regulation via inhibition of caspase activities in erythropoietin signaling.
Journal of cellular physiology 2003;195(2):290-7.
2003: Ozawa Keiya
[Hematopoietic malignancies and gene therapy]
Gan to kagaku ryoho. Cancer & chemotherapy 2003;30(4):478-82.
2003: Hanazono Yutaka; Asano Takayuki; Ueda Yasuji; Ozawa Keiya
Genetic manipulation of primate embryonic and hematopoietic stem cells with simian lentivirus vectors.
Trends in cardiovascular medicine 2003;13(3):106-10.
2003: Nomoto Tatsuya; Okada Takashi; Shimazaki Kuniko; Mizukami Hiroaki; Matsushita Takashi; Hanazono Yutaka; Kume Akihiro; Katsura Ken-ichiro; Katayama Yasuo; Ozawa Keiya
Distinct patterns of gene transfer to gerbil hippocampus with recombinant adeno-associated virus type 2 and 5.
Neuroscience letters 2003;340(2):153-7.
2003: Kume Akihiro; Koremoto Masahide; Xu Ruifang; Okada Takashi; Mizukami Hiroaki; Hanazono Yutaka; Hasegawa Mamoru; Ozawa Keiya
In vivo expansion of transduced murine hematopoietic cells with a selective amplifier gene.
The journal of gene medicine 2003;5(3):175-81.
2003: Nagashima Takeyuki; Ueda Yasuji; Hanazono Yutaka; Kume Akihiro; Shibata Hiroaki; Ageyama Naohide; Terao Keiji; Ozawa Keiya; Hasegawa Mamoru
New selective amplifier genes containing c-Mpl for hematopoietic cell expansion.
Biochemical and biophysical research communications 2003;303(1):170-6.
2003: Noborio Kaoru; Muroi Kazuo; Izumi Tohru; Toshima Masaki; Kawano-Yamamoto Chizuru; Otsuki Tetsuya; Nagai Tadashi; Komatsu Norio; Ozawa Keiya
Massive immune hemolysis after non-myeloablative allogeneic peripheral blood stem cell transplantation with minor ABO-incompatibility.
Leukemia & lymphoma 2003;44(2):357-9.
2003: Komatsu Norio; Watanabe Tomoko; Uchida Mie; Mori Masaki; Kirito Keita; Kikuchi Satoru; Liu Qifa; Tauchi Tetsuzo; Miyazawa Keisuke; Endo Hitoshi; Nagai Tadashi; Ozawa Keiya
A member of Forkhead transcription factor FKHRL1 is a downstream effector of STI571-induced cell cycle arrest in BCR-ABL-expressing cells.
The Journal of biological chemistry 2003;278(8):6411-9.
2003: Kami Masahiro; Hamaki Tamae; Miyakoshi Shigesaburo; Murashige Naoko; Kanda Yoshinobu; Tanosaki Ryuji; Takaue Yoichi; Taniguchi Shuichi; Hirai Hisamaru; Ozawa Keiya; Kasai Masaharu
Allogeneic haematopoietic stem cell transplantation for the treatment of adult T-cell leukaemia/lymphoma.
British journal of haematology 2003;120(2):304-9.
2003: Kanazawa T; Mizukami H; Okada T; Hanazono Y; Kume A; Nishino H; Takeuchi K; Kitamura K; Ichimura K; Ozawa K
Suicide gene therapy using AAV-HSVtk/ganciclovir in combination with irradiation results in regression of human head and neck cancer xenografts in nude mice.
Gene therapy 2003;10(1):51-8.
2003: Lu Yan-Yan; Wang Li-Jun; Muramatsu Shin-ichi; Ikeguchi Kunihiko; Fujimoto Ken-ichi; Okada Takashi; Mizukami Hiroaki; Matsushita Takashi; Hanazono Yutaka; Kume Akihiro; Nagatsu Toshiharu; Ozawa Keiya; Nakano Imaharu
Intramuscular injection of AAV-GDNF results in sustained expression of transgenic GDNF, and its delivery to spinal motoneurons by retrograde transport.
Neuroscience research 2003;45(1):33-40.
2003: Muramatsu Shin-ichi; Wang Lijun; Ikeguchi Kunihiko; Fujimoto Ken-ichi; Nakano Imaharu; Okada Takashi; Mizukami Hiroaki; Hanazono Yutaka; Kume Akihiro; Nakano Imaharu; Ozawa Keiya
Adeno-associated viral vectors for Parkinson's disease.
International review of neurobiology 2003;55():205-22.
2003: Ohmine Ken; Nagai Tadashi; Tarumoto Takahisa; Miyoshi Takuji; Muroi Kazuo; Mano Hiroyuki; Komatsu Norio; Takaku Fumimaro; Ozawa Keiya
Analysis of gene expression profiles in an imatinib-resistant cell line, KCL22/SR.
Stem cells (Dayton, Ohio) 2003;21(3):315-21.
2002: Tri Nguyen Khanh; Xinh Phan Thi; Nagao Hiromasa; Izumi Tohru; Ozawa Keiya; Toyoda Atsushi; Hattori Masahira; Sakaki Yoshiyuki; Tokunaga Katsushi; Sato Yuko
Identification of the breakpoints at 1p36.2 and 3p21.3 in an AML(M3) patient who had t(1;3)(p36.2;p21.3) at the third relapse.
Genes, chromosomes & cancer 2002;35(4):365-7.
2002: Kawano-Yamamoto Chizuru; Muroi Kazuo; Izumi Thoru; Saito Ken; Ozawa Keiya
Two-color flow cytometry with a CD19 gate for the evaluation of bone marrow involvement of B-cell lymphoma.
Leukemia & lymphoma 2002;43(11):2133-7.
2002: Kume Akihiro; Hanazono Yutaka; Mizukami Hiroaki; Okada Takashi; Ozawa Keiya
Selective expansion of transduced cells for hematopoietic stem cell gene therapy.
International journal of hematology 2002;76(4):299-304.
2002: Miyoshi Takuji; Otsuki Tetsuya; Omine Ken; Kirito Keita; Nagai Tadashi; Izumi Tohru; Komatsu Norio; Madoiwa Seiji; Mimuro Jun; Sakata Yoichi; Ozawa Keiya
[Acute promyelocytic leukemia accompanied by retinoic acid syndrome with complications of acute myocardial infarction and cerebral infarction during treatment with all-trans retinoic acid]
[Rinsho ketsueki] The Japanese journal of clinical hematology 2002;43(10):954-9.
2002: Okada Takashi; Nomoto Tatsuya; Shimazaki Kuniko; Lijun Wang; Lu Yanyan; Matsushita Takashi; Mizukami Hiroaki; Urabe Masashi; Hanazono Yutaka; Kume Akihiro; Muramatsu Shin-ichi; Nakano Imaharu; Ozawa Keiya
Adeno-associated virus vectors for gene transfer to the brain.
Methods (San Diego, Calif.) 2002;28(2):237-47.
2002: Ageyama Naohide; Hanazono Yutaka; Shibata Hiroaki; Ohto Keiko; Ono Fumiko; Nagashima Takeyuki; Ueda Yasuji; Donahue Robert E; Hasegawa Mamoru; Ozawa Keiya; Yoshikawa Yasuhiro; Terao Keiji
Safe and efficient methods of autologous hematopoietic stem cell transplantation for biomedical research in cynomolgus monkeys.
Comparative medicine 2002;52(5):445-51.
2002: Kobayashi Naomi; Koshino Tomihisa; Uesugi Masaaki; Yokoo Naoki; Xin Ke-Qin; Okuda Kenji; Mizukami Hiroaki; Ozawa Keiya; Saito Tomoyuki
Gene marking in adeno-associated virus vector infected periosteum derived cells for cartilage repair.
The Journal of rheumatology 2002;29(10):2176-80.
2002: Muramatsu Shin-Ichi; Wang Lijun; Ikeguchi Kunihiko; Fujimoto Ken-Ichi; Nakano Imaharu; Ozawa Keiya
Recombinant adeno-associated viral vectors bring gene therapy for Parkinson's disease closer to reality.
Journal of neurology 2002;249 Suppl 2():II36-40.
2002: Xin Ke-Qin; Ooki Takaaki; Mizukami Hiroaki; Hamajima Kenji; Okudela Koji; Hashimoto Kumiko; Kojima Yoshitsugu; Jounai Nao; Kumamoto Yasuko; Sasaki Shin; Klinman Dennis; Ozawa Keiya; Okuda Kenji
Oral administration of recombinant adeno-associated virus elicits human immunodeficiency virus-specific immune responses.
Human gene therapy 2002;13(13):1571-81.
2002: Hanazono Yutaka; Terao Keiji; Shibata Hiroaki; Nagashima Takeyuki; Ageyama Naohide; Asano Takayuki; Ueda Yasuji; Kato Ikunoshin; Kume Akihiro; Hasegawa Mamoru; Ozawa Keiya
Introduction of the green fluorescent protein gene into hematopoietic stem cells results in prolonged discrepancy of in vivo transduction levels between bone marrow progenitors and peripheral blood cells in nonhuman primates.
The journal of gene medicine 2002;4(5):470-7.
2002: Wang Li-Jun; Lu Yan-Yan; Muramatsu Shin-ichi; Ikeguchi Kunihiko; Fujimoto Ken-ichi; Okada Takashi; Mizukami Hiroaki; Matsushita Takashi; Hanazono Yutaka; Kume Akihiro; Nagatsu Toshiharu; Ozawa Keiya; Nakano Imaharu
Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(16):6920-8.
2002: Asano Takayuki; Hanazono Yutaka; Ueda Yasuji; Muramatsu Shin-ichi; Kume Akihiro; Suemori Hirofumi; Suzuki Yutaka; Kondo Yasushi; Harii Kiyonori; Hasegawa Mamoru; Nakatsuji Norio; Ozawa Keiya
Highly efficient gene transfer into primate embryonic stem cells with a simian lentivirus vector.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(2):162-8.
2002: Hanazono Y; Nagashima T; Takatoku M; Shibata H; Ageyama N; Asano T; Ueda Y; Dunbar C E; Kume A; Terao K; Hasegawa M; Ozawa K
In vivo selective expansion of gene-modified hematopoietic cells in a nonhuman primate model.
Gene therapy 2002;9(16):1055-64.
2002: Muroi Kazuo; Kawano Chizuru; Yokote Taiji; Otsuki Tetsuya; Kirito Keita; Komatsu Norio; Ozawa Keiya
Early myelodysplastic syndrome after allogeneic bone marrow transplantation for acute myeloid leukemia.
Leukemia & lymphoma 2002;43(7):1493-6.
2002: Nagai Tadashi; Izumi Tohru; Noborio Kaoru; Takatoku Masaaki; Ohtsuki Tetsuya; Machii Takashi; Komatsu Norio; Ozawa Keiya
[Successful treatment of hairy cell leukemia prolymphocytic variant with 2'-deoxycoformycin]
[Rinsho ketsueki] The Japanese journal of clinical hematology 2002;43(7):583-5.
2002: Ozawa Keiya
[Progress in the field of hematology in the last 100 years: Gene therapy]
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2002;91(7):2003-6.
2002: Kume A; Koremoto M; Mizukami H; Okada T; Hanazono Y; Sugamura K; Ozawa K
Selective growth advantage of wild-type lymphocytes in X-linked SCID recipients.
Bone marrow transplantation 2002;30(2):113-8.
2002: Sato Yuko; Izumi Tohru; Kanamori Hirakazu; Davis Elizabeth M; Miura Yasusada; Larson Richard A; Le Beau Michelle M; Ozawa Keiya; Rowley Janet D
t(1;3)(p36;p21) is a recurring therapy-related translocation.
Genes, chromosomes & cancer 2002;34(2):186-92.
2002: Mishima Yuji; Terui Yasuhito; Mishima Yuko; Katsuyama Misa; Mori Masaki; Tomizuka Hiroshi; Takizawa Toshiyuki; Miyazato Akira; Ueda Masuzu; Yamada Muneo; Hayasawa Hirotoshi; Mizunuma Nobuyuki; Ishizaka Yukihito; Ikeda Kazuma; Kato Takashi; Ozawa Keiya; Hatake Kiyohiko
New human myelodysplastic cell line, TER-3: G-CSF specific downregulation of Ca2+/calmodulin-dependent protein kinase IV.
Journal of cellular physiology 2002;191(2):183-90.
2002: Imagawa Shigehiko; Suzuki Norio; Ohmine Ken; Obara Naoshi; Mukai Harumi Y; Ozawa Keiya; Yamamoto Masayuki; Nagasawa Toshiro
GATA suppresses erythropoietin gene expression through GATA site in mouse erythropoietin gene promoter.
International journal of hematology 2002;75(4):376-81.
2002: Saga Yasushi; Mizukami Hiroaki; Suzuki Mitsuaki; Kohno Takahiro; Urabe Masashi; Ozawa Keiya; Sato Ikuo
Overexpression of PTEN increases sensitivity to SN-38, an active metabolite of the topoisomerase I inhibitor irinotecan, in ovarian cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(5):1248-52.
2002: Kirito Keita; Osawa Masatake; Morita Haruhiko; Shimizu Ritsuko; Yamamoto Masayuki; Oda Atsushi; Fujita Hiroyoshi; Tanaka Masaru; Nakajima Koichi; Miura Yasusada; Ozawa Keiya; Komatsu Norio
A functional role of Stat3 in in vivo megakaryopoiesis.
Blood 2002;99(9):3220-7.
2002: Yokote Taiji; Muroi Kazuo; Kawano Chizuru; Kirto Keita; Ohtsuki Tetsuya; Komatsu Norio; Murakami Takashi; Takahashi Kazuo; Ozawa Keiya
Human herpesvirus-6-associated generalized vesiculobullous eruptions after allogeneic bone marrow transplantation.
Leukemia & lymphoma 2002;43(4):927-9.
2002: Hasumi Yoko; Mizukami Hiroaki; Urabe Masashi; Kohno Takahiro; Takeuchi Koichi; Kume Akihiro; Momoeda Mikio; Yoshikawa Hiroyuki; Tsuruo Takashi; Shibuya Masabumi; Taketani Yuji; Ozawa Keiya
Soluble FLT-1 expression suppresses carcinomatous ascites in nude mice bearing ovarian cancer.
Cancer research 2002;62(7):2019-23.
2002: Wang L; Muramatsu S; Lu Y; Ikeguchi K; Fujimoto K; Okada T; Mizukami H; Hanazono Y; Kume A; Urano F; Ichinose H; Nagatsu T; Nakano I; Ozawa K
Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease.
Gene therapy 2002;9(6):381-9.
2002: Shimpo Masahisa; Ikeda Uichi; Maeda Yoshikazu; Takahashi Masafumi; Miyashita Hiroshi; Mizukami Hiroaki; Urabe Masashi; Kume Akihiro; Takizawa Toshihiro; Shibuya Masabumi; Ozawa Keiya; Shimada Kazuyuki
AAV-mediated VEGF gene transfer into skeletal muscle stimulates angiogenesis and improves blood flow in a rat hindlimb ischemia model.
Cardiovascular research 2002;53(4):993-1001.
2002: Otsuki Tetsuya; Nagashima Takahiro; Komatsu Norio; Kirito Keita; Furukawa Yusuke; Kobayashi Si Shin-ichi; Liu Johnson M; Ozawa Keiya
Phosphorylation of Fanconi anemia protein, FANCA, is regulated by Akt kinase.
Biochemical and biophysical research communications 2002;291(3):628-34.
2002: Kirito Keita; Watanabe Tomoko; Sawada Ken-ichi; Endo Hitoshi; Ozawa Keiya; Komatsu Norio
Thrombopoietin regulates Bcl-xL gene expression through Stat5 and phosphatidylinositol 3-kinase activation pathways.
The Journal of biological chemistry 2002;277(10):8329-37.
2002: Muramatsu Shin-Ichi; Fujimoto Ken-Ichi; Ikeguchi Kunihiko; Shizuma Nami; Kawasaki Katsuyoshi; Ono Fumiko; Shen Yang; Wang Lijun; Mizukami Hiroaki; Kume Akihiro; Matsumura Masaru; Nagatsu Ikuko; Urano Fumi; Ichinose Hiroshi; Nagatsu Toshiharu; Terao Keiji; Nakano Imaharu; Ozawa Keiya
Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes.
Human gene therapy 2002;13(3):345-54.
2002: Imagawa Shigehiko; Tarumoto Takahisa; Suzuki Norio; Mukai Harumi Y; Hasegawa Yuichi; Higuchi Masato; Neichi Tomohiro; Ozawa Keiya; Yamamoto Masayuki; Nagasawa Toshiro
L-arginine rescues decreased erythropoietin gene expression by stimulating GATA-2 with L-NMMA.
Kidney international 2002;61(2):396-404.
2002: Kirito Keita; Nagashima Toshihiro; Ozawa Keiya; Komatsu Norio
Constitutive activation of Stat1 and Stat3 in primary erythroleukemia cells.
International journal of hematology 2002;75(1):51-4.
2002: Kawada Tomie; Nakazawa Mikio; Nakauchi Sakura; Yamazaki Ken; Shimamoto Ryoichi; Urabe Masashi; Nakata Jumi; Hemmi Chieko; Masui Fujiko; Nakajima Toshiaki; Suzuki Jun-Ichi; Monahan John; Sato Hiroshi; Masaki Tomoh; Ozawa Keiya; Toyo-Oka Teruhiko
Rescue of hereditary form of dilated cardiomyopathy by rAAV-mediated somatic gene therapy: amelioration of morphological findings, sarcolemmal permeability, cardiac performances, and the prognosis of TO-2 hamsters.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(2):901-6.
2002: Kirito Keita; Nakajima Koichi; Watanabe Tomoko; Uchida Mie; Tanaka Masaru; Ozawa Keiya; Komatsu Norio
Identification of the human erythropoietin receptor region required for Stat1 and Stat3 activation.
Blood 2002;99(1):102-10.
2002: Kishino Koji; Muroi Kazuo; Kawano Chizuru; Obata Takashi; Sugano Naoko; Nakagi Yoko; Nagashima Takahiro; Watari Kiyoshi; Iwamoto Sadahiko; Ozawa Keiya
Evaluation of engraftment by ABO genotypic analysis of erythroid burst-forming units after bone marrow transplantation.
Leukemia research 2002;26(1):13-7.
2002: Toyo-oka Teruhiko; Kawada Tomie; Xi Hang; Nakazawa Mikio; Masui Fujiko; Hemmi Chieko; Nakata Jumi; Tezuka Asaki; Iwasawa Kuniaki; Urabe Masashi; Monahan John; Ozawa Keiya
Gene therapy prevents disruption of dystrophin-related proteins in a model of hereditary dilated cardiomyopathy in hamsters.
Heart, lung & circulation 2002;11(3):174-81.
2002: Tanaka Masashi; Borgeld Harm-Jan; Zhang Jin; Muramatsu Shin-ichi; Gong Jian-Sheng; Yoneda Makoto; Maruyama Wakako; Naoi Makoto; Ibi Tohru; Sahashi Ko; Shamoto Masayo; Fuku Noriyuki; Kurata Miyuki; Yamada Yoshiji; Nishizawa Kumi; Akao Yukihiro; Ohishi Nobuko; Miyabayashi Shigeaki; Umemoto Hiraku; Muramatsu Tatsuo; Furukawa Koichi; Kikuchi Akihiko; Nakano Imaharu; Ozawa Keiya; Yagi Kunio
Gene therapy for mitochondrial disease by delivering restriction endonuclease SmaI into mitochondria.
Journal of biomedical science 2002;9(6 Pt 1):534-41.
2002: Saga Yasushi; Suzuki Mitsuaki; Mizukami Hiroaki; Urabe Masashi; Fukushima Masakuza; Ozawa Keiya; Sato Ikuo
Enhanced expression of thymidylate synthase mediates resistance of uterine cervical cancer cells to radiation.
Oncology 2002;63(2):185-91.
2002: Okada Takashi; Shimazaki Kuniko; Nomoto Tatsuya; Matsushita Takashi; Mizukami Hiroaki; Urabe Masashi; Hanazono Yutaka; Kume Akihiro; Tobita Kiyotake; Ozawa Keiya; Kawai Nobufumi
Adeno-associated viral vector-mediated gene therapy of ischemia-induced neuronal death.
Methods in enzymology 2002;346():378-93.
2001: Fan D; Shen Y; Kang D; Nakano I; Ozawa K
Adeno-associated virus vector-mediated triple gene transfer of dopamine synthetic enzymes.
Chinese medical journal 2001;114(12):1276-9.
2001: Ohmine K; Ota J; Ueda M; Ueno S; Yoshida K; Yamashita Y; Kirito K; Imagawa S; Nakamura Y; Saito K; Akutsu M; Mitani K; Kano Y; Komatsu N; Ozawa K; Mano H
Characterization of stage progression in chronic myeloid leukemia by DNA microarray with purified hematopoietic stem cells.
Oncogene 2001;20(57):8249-57.
2001: Mimuro J; Muramatsu S; Hakamada Y; Mori K; Kikuchi J; Urabe M; Madoiwa S; Ozawa K; Sakata Y
Recombinant adeno-associated virus vector-transduced vascular endothelial cells express the thrombomodulin transgene under the regulation of enhanced plasminogen activator inhibitor-1 promoter.
Gene therapy 2001;8(22):1690-7.
2001: Otsuki T; Furukawa Y; Ikeda K; Endo H; Yamashita T; Shinohara A; Iwamatsu A; Ozawa K; Liu J M
Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex.
Human molecular genetics 2001;10(23):2651-60.
2001: Okada T; Mizukami H; Urabe M; Nomoto T; Matsushita T; Hanazono Y; Kume A; Tobita K; Ozawa K
Development and characterization of an antisense-mediated prepackaging cell line for adeno-associated virus vector production.
Biochemical and biophysical research communications 2001;288(1):62-8.
2001: Mori M; Hatake K; Tanaka M; Takatoku M; Matsumoto Y; Uchida M; Kametaka M; Nagai T; Terui Y; Tomizuka H; Muroi K; Ozawa K
CAM-cytarabine, aclarubicin plus macrophage colony-stimulating factor in the treatment of acute myelogenous leukemia with trilineage dysplasia: usefulness of in vitro apoptosis in leukemic cells.
Leukemia & lymphoma 2001;42(3):387-91.
2001: Muramatsu M; Hanazono Y; Ogasawara Y; Okada T; Mizukami H; Kume A; Mizoguchi H; Ozawa K
Reversible integration of the dominant negative retinoid receptor gene for ex vivo expansion of hematopoietic stem/progenitor cells.
Biochemical and biophysical research communications 2001;285(4):891-6.
2001: Miyazato A; Ueno S; Ohmine K; Ueda M; Yoshida K; Yamashita Y; Kaneko T; Mori M; Kirito K; Toshima M; Nakamura Y; Saito K; Kano Y; Furusawa S; Ozawa K; Mano H
Identification of myelodysplastic syndrome-specific genes by DNA microarray analysis with purified hematopoietic stem cell fraction.
Blood 2001;98(2):422-7.
2001: Kogure K; Urabe M; Mizukami H; Kume A; Sato Y; Monahan J; Ozawa K
Targeted integration of foreign DNA into a defined locus on chromosome 19 in K562 cells using AAV-derived components.
International journal of hematology 2001;73(4):469-75.
2001: Xin K Q; Urabe M; Yang J; Nomiyama K; Mizukami H; Hamajima K; Nomiyama H; Saito T; Imai M; Monahan J; Okuda K; Ozawa K; Okuda K
A novel recombinant adeno-associated virus vaccine induces a long-term humoral immune response to human immunodeficiency virus.
Human gene therapy 2001;12(9):1047-61.
2001: Kawada T; Sakamoto A; Nakazawa M; Urabe M; Masuda F; Hemmi C; Wang Y; Shin W S; Nakatsuru Y; Sato H; Ozawa K; Toyo-oka T
Morphological and physiological restorations of hereditary form of dilated cardiomyopathy by somatic gene therapy.
Biochemical and biophysical research communications 2001;284(2):431-5.
2001: Mori M; Terui Y; Tanaka M; Tomizuka H; Mishima Y; Ikeda M; Kasahara T; Uwai M; Ueda M; Inoue R; Itoh T; Yamada M; Hayasawa H; Furukawa Y; Ishizaka Y; Ozawa K; Hatake K
Antitumor effect of beta2-microglobulin in leukemic cell-bearing mice via apoptosis-inducing activity: activation of caspase-3 and nuclear factor-kappaB.
Cancer research 2001;61(11):4414-7.
2001: Nagashima T; Muroi K; Kunitama M; Izumi T; Ohtsuki T; Komatsu N; Fukayama M; Ozawa K
Colon cancer with meningeal carcinomatosis and myelodysplastic syndrome in a patient who underwent intensive chemotherapy for acute myelogenous leukemia: a case report.
Japanese journal of clinical oncology 2001;31(5):221-5.
2001: Tanaka M; Kirito K; Kashii Y; Uchida M; Watanabe T; Endo H; Endoh T; Sawada K; Ozawa K; Komatsu N
Forkhead family transcription factor FKHRL1 is expressed in human megakaryocytes. Regulation of cell cycling as a downstream molecule of thrombopoietin signaling.
The Journal of biological chemistry 2001;276(18):15082-9.
2001: Kanazawa T; Urabe M; Mizukami H; Okada T; Kume A; Nishino H; Monahan J; Kitamura K; Ichimura K; Ozawa K
Gamma-rays enhance rAAV-mediated transgene expression and cytocidal effect of AAV-HSVtk/ganciclovir on cancer cells.
Cancer gene therapy 2001;8(2):99-106.
2001: Tabata M; Tarumoto T; Ohmine K; Furukawa Y; Hatake K; Ozawa K; Hasegawa Y; Mukai H; Yamamoto M; Imagawa S
Stimulation of GATA-2 as a mechanism of hydrogen peroxide suppression in hypoxia-induced erythropoietin gene expression.
Journal of cellular physiology 2001;186(2):260-7.
2001: Shinjyo T; Kuribara R; Inukai T; Hosoi H; Kinoshita T; Miyajima A; Houghton P J; Look A T; Ozawa K; Inaba T
Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors.
Molecular and cellular biology 2001;21(3):854-64.
2001: Maeda Y; Ikeda U; Oya K; Shimpo M; Ueno S; Urabe M; Kume A; Monahan J; Ozawa K; Shimada K
Adeno-associated virus-mediated transfer of endothelial nitric oxide synthase gene inhibits protein synthesis of rat ventricular cardiomyocytes.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2001;15(1):19-24.
2001: Uchida M; Kirito K; Shimizu R; Miura Y; Ozawa K; Komatsu N
A functional role of mitogen-activated protein kinases, erk1 and erk2, in the differentiation of a human leukemia cell line, UT-7/GM: a possible key factor for cell fate determination toward erythroid and megakaryocytic lineages.
International journal of hematology 2001;73(1):78-83.
2001: Matsumoto Y; Mori M; Ohtsuki T; Muroi K; Hatake K; Komatsu N; Ozawa K
[Outcome of acute myelogenous leukemia in 41 patients treated with idarubicin: the prognosis of t(8;21) cases]
[Rinsho ketsueki] The Japanese journal of clinical hematology 2001;42(1):15-22.
2001: Ozawa K
[Perspectives on postgenome medicine: Hematological diseases]
Nippon rinsho. Japanese journal of clinical medicine 2001;59(1):59-64.
2001: Hanazono Y; Terao K; Ozawa K
Gene transfer into nonhuman primate hematopoietic stem cells: implications for gene therapy.
Stem cells (Dayton, Ohio) 2001;19(1):12-23.
2000: Kawano C; Muroi K; Akioka T; Izumi T; Kodera Y; Ozawa K
Cytomegalovirus pneumonitis, activated prothrombin time prolongation and subacute thyroiditis after unrelated allogeneic bone marrow transplantation.
Bone marrow transplantation 2000;26(12):1347-9.
2000: Ichida M; Imagawa S; Ohmine K; Komatsu N; Hatake K; Ozawa K; Miura Y
Successful treatment of multiple myeloma--associated amyloidosis by interferon-alpha, dimethyl sulfoxide, and VAD (vincristine, adriamycin, and dexamethasone).
International journal of hematology 2000;72(4):491-3.
2000: Uwai M; Terui Y; Mishima Y; Tomizuka H; Ikeda M; Itoh T; Mori M; Ueda M; Inoue R; Yamada M; Hayasawa H; Horiuchi T; Niho Y; Matsumoto M; Ishizaka Y; Ikeda K; Ozawa K; Hatake K
A new apoptotic pathway for the complement factor B-derived fragment Bb.
Journal of cellular physiology 2000;185(2):280-92.
2000: Toshima M; Nagai T; Izumi T; Tarumoto T; Takatoku M; Imagawa S; Komatsu N; Ozawa K
All-trans-retinoic acid treatment for chemotherapy-resistant acute adult T-cell leukemia.
International journal of hematology 2000;72(3):343-5.
2000: Muroi K; Tarumoto T; Akioka T; Kirito K; Nagai T; Izumi T; Nakamura M; Hatake K; Hakomori S; Miura Y; Ozawa K
Sialyl-Tn- and neuron-specific enolase-positive minimally differentiated erythroleukemia.
Internal medicine (Tokyo, Japan) 2000;39(10):843-6.
2000: Chen H; Ikeda U; Shimpo M; Maeda Y; Shibuya M; Ozawa K; Shimada K
Inhibition of vascular endothelial growth factor activity by transfection with the soluble FLT-1 gene.
Journal of cardiovascular pharmacology 2000;36(4):498-502.
2000: Maeda Y; Ikeda U; Shimpo M; Shibuya M; Monahan J; Urabe M; Ozawa K; Shimada K
Adeno-associated virus-mediated vascular endothelial growth factor gene transfer into cardiac myocytes.
Journal of cardiovascular pharmacology 2000;36(4):438-43.
2000: Urabe M; Shimazaki K; Saga Y; Okada T; Kume A; Tobita K; Ozawa K
Self-amplification system for recombinant adeno-associated virus production.
Biochemical and biophysical research communications 2000;276(2):559-63.
2000: Tarumoto T; Imagawa S; Ohmine K; Nagai T; Higuchi M; Imai N; Suzuki N; Yamamoto M; Ozawa K
N(G)-monomethyl-L-arginine inhibits erythropoietin gene expression by stimulating GATA-2.
Blood 2000;96(5):1716-22.
2000: Tarumoto T; Imagawa S; Ohmine K; Mano A; Nagai T; Takatoku M; Muroi K; Hatake K; Ozawa K
A de novo philadelphia chromosome-positive acute mixed-lineage leukemia with both major and minor BCR/ABL mRNA transcripts.
American journal of hematology 2000;65(1):72-4.
2000: Matsumoto Y; Kawano C; Kametaka M; Otsuki T; Hatake K; Muroi K; Ozawa K
Phenotypic conversion of T-lineage lymphoblasts in the lymph node to myeloblasts in the bone marrow during relapse after allogeneic bone marrow transplantation.
International journal of hematology 2000;72(2):253-4.
2000: Kashii Y; Uchida M; Kirito K; Tanaka M; Nishijima K; Toshima M; Ando T; Koizumi K; Endoh T; Sawada K; Momoi M; Miura Y; Ozawa K; Komatsu N
A member of Forkhead family transcription factor, FKHRL1, is one of the downstream molecules of phosphatidylinositol 3-kinase-Akt activation pathway in erythropoietin signal transduction.
Blood 2000;96(3):941-9.
2000: Tabata M; Imagawa S; Tarumoto T; Ohmine K; Hatake K; Miura Y; Ozawa K
Essential thrombocythemia transformed to acute myelogenous leukemia with t(3;17)(p24; q12), del(5)(q13q34) after treatment with carboquone and hydroxyurea.
Japanese journal of clinical oncology 2000;30(7):310-2.
2000: Shen Y; Muramatsu S I; Ikeguchi K; Fujimoto K I; Fan D S; Ogawa M; Mizukami H; Urabe M; Kume A; Nagatsu I; Urano F; Suzuki T; Ichinose H; Nagatsu T; Monahan J; Nakano I; Ozawa K
Triple transduction with adeno-associated virus vectors expressing tyrosine hydroxylase, aromatic-L-amino-acid decarboxylase, and GTP cyclohydrolase I for gene therapy of Parkinson's disease.
Human gene therapy 2000;11(11):1509-19.
2000: Kawano C; Muroi K; Yozhizawa M; Kirikae T; Ozawa K
Filamented Pseudomonas aeruginosa and a markedly high level of endotoxin in cerebrospinal fluid.
The Journal of infection 2000;41(1):114-5.
2000: Kume A; Xu R; Ueda Y; Urabe M; Ozawa K
Long-term tracking of murine hematopoietic cells transduced with a bicistronic retrovirus containing CD24 and EGFP genes.
Gene therapy 2000;7(14):1193-9.
2000: Muroi K; Suzuki T; Amemiya Y; Yoshida M; Kawano C; Kuribara R; Otsuki T; Izumi T; Tomizuka H; Komatsu N; Imagawa S; Hatake K; Miura Y; Ozawa K
Autologous peripheral blood stem cell transplantation for adults with B-lineage acute lymphoblastic leukemia: a pilot study.
Leukemia & lymphoma 2000;38(1-2):103-11.
2000: Matsuda K M; Madoiwa S; Hasumi Y; Kanazawa T; Saga Y; Kume A; Mano H; Ozawa K; Matsuda M
A novel strategy for the tumor angiogenesis-targeted gene therapy: generation of angiostatin from endogenous plasminogen by protease gene transfer.
Cancer gene therapy 2000;7(4):589-96.
2000: Tarumoto T; Imagawa S; Hotta T; Ohmine K; Nagai T; Takatoku M; Komatsu N; Hatake K; Ozawa K
A case of bilateral heel ulcers associated with hydroxyurea therapy for chronic myelogenous leukemia.
Japanese journal of clinical oncology 2000;30(3):159-62.
2000: Izumi T; Ozawa K
[Clinical staging classification of non-Hodgkin's lymphoma]
Nippon rinsho. Japanese journal of clinical medicine 2000;58(3):598-601.
2000: Urabe M; Kume A; Tobita K; Ozawa K
DNA/Calcium phosphate precipitates mixed with medium are stable and maintain high transfection efficiency.
Analytical biochemistry 2000;278(1):91-2.
2000: Kawano C; Muroi K; Kuribara R; Matsumoto Y; Ohtsuki T; Hatake K; Ozawa K
Engraftment syndrome after autologous peripheral blood stem cell transplantation with high numbers of peripheral blood stem cells followed by granulocyte colony-stimulating factor administration.
Bone marrow transplantation 2000;25(2):228-9.
2000: Ozawa K; Fan D S; Shen Y; Muramatsu S; Fujimoto K; Ikeguchi K; Ogawa M; Urabe M; Kume A; Nakano I
Gene therapy of Parkinson's disease using adeno-associated virus (AAV) vectors.
Journal of neural transmission. Supplementum 2000;(58):181-91.
1999: Ozawa K
[Current status of gene therapy and prospect of its clinical application]
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 1999;22(6):391-3.
1999: Urabe M; Kume A; Takahashi T; Serizawa N; Tobita K; Ozawa K
A switching system regulating subcellular localization of nuclear proteins using a viral protease.
Biochemical and biophysical research communications 1999;266(1):92-6.
1999: Otsuki T; Kajigaya S; Ozawa K; Liu J M
SNX5, a new member of the sorting nexin family, binds to the Fanconi anemia complementation group A protein.
Biochemical and biophysical research communications 1999;265(3):630-5.
1999: Terui Y; Tomizuka H; Mishima Y; Ikeda M; Kasahara T; Uwai M; Mori M; Itoh T; Tanaka M; Yamada M; Shimamura S; Ishizaka Y; Ozawa K; Hatake K
NH2-terminal pentapeptide of endothelial interleukin 8 is responsible for the induction of apoptosis in leukemic cells and has an antitumor effect in vivo.
Cancer research 1999;59(22):5651-5.
1999: Mori M; Tanaka T; Akifuji Y; Ueki J; Nakamoto S; Uwai M; Terui Y; Tomizuka H; Hatake K; Ozawa K; Miura Y
[Moderate aplastic anemia associated with Crohn's disease during antithymocyte globulin treatment]
[Rinsho ketsueki] The Japanese journal of clinical hematology 1999;40(10):1105-9.
1999: Mori M; Terui Y; Ikeda M; Tomizuka H; Uwai M; Kasahara T; Kubota N; Itoh T; Mishima Y; Douzono-Tanaka M; Yamada M; Shimamura S; Kikuchi J; Furukawa Y; Ishizaka Y; Ikeda K; Mano H; Ozawa K; Hatake K
Beta(2)-microglobulin identified as an apoptosis-inducing factor and its characterization.
Blood 1999;94(8):2744-53.
1999: Ogasawara Y; Mizukami H; Urabe M; Kume A; Kanegae Y; Saito I; Monahan J; Ozawa K
Highly regulated expression of adeno-associated virus large Rep proteins in stable 293 cell lines using the Cre/loxP switching system.
The Journal of general virology 1999;80 ( Pt 9)():2477-80.
1999: Matsumoto Y; Mori M; Kanai N; Izumi T; Takatoku M; Muroi K; Imagawa S; Komatsu N; Hatake K; Sakata Y; Saito K; Ozawa K
[Systemic lupus erythematosus presenting as fulminant thrombotic thrombocytopenic purpura]
[Rinsho ketsueki] The Japanese journal of clinical hematology 1999;40(8):673-7.
1999: Hamada K; Ozawa K; Itami S; Yoshikawa K
Human fibroblast growth factor 10 expression in dermal papilla cells, outer root sheath cells and keratinocytes.
Experimental dermatology 1999;8(4):347-9.
1999: Xu R; Kume A; Matsuda K M; Ueda Y; Kodaira H; Ogasawara Y; Urabe M; Kato I; Hasegawa M; Ozawa K
A selective amplifier gene for tamoxifen-inducible expansion of hematopoietic cells.
The journal of gene medicine 1999;1(4):236-44.
1999: Matsuda K M; Kume A; Ueda Y; Urabe M; Hasegawa M; Ozawa K
Development of a modified selective amplifier gene for hematopoietic stem cell gene therapy.
Gene therapy 1999;6(6):1038-44.
1999: Kume A; Hanazono Y; Mizukami H; Urabe M; Ozawa K
Hematopoietic stem cell gene therapy: a current overview.
International journal of hematology 1999;69(4):227-33.
1999: Kume A; Ito K; Ueda Y; Hasegawa M; Urabe M; Mano H; Ozawa K
A G-CSF receptor-gyrase B fusion gene: A new type of molecular switch for expansion of genetically modified hematopoietic cells.
Biochemical and biophysical research communications 1999;260(1):9-12.
1999: Ogasawara Y; Urabe M; Kogure K; Kume A; Colosi P; Kurtzman G J; Ozawa K
Efficient production of adeno-associated virus vectors using split-type helper plasmids.
Japanese journal of cancer research : Gann 1999;90(4):476-83.
1999: Kuribara R; Kinoshita T; Miyajima A; Shinjyo T; Yoshihara T; Inukai T; Ozawa K; Look A T; Inaba T
Two distinct interleukin-3-mediated signal pathways, Ras-NFIL3 (E4BP4) and Bcl-xL, regulate the survival of murine pro-B lymphocytes.
Molecular and cellular biology 1999;19(4):2754-62.
1999: Urabe M; Hasumi Y; Kume A; Surosky R T; Kurtzman G J; Tobita K; Ozawa K
Charged-to-alanine scanning mutagenesis of the N-terminal half of adeno-associated virus type 2 Rep78 protein.
Journal of virology 1999;73(4):2682-93.
1999: Kume A; Hashiyama M; Suda T; Ozawa K
Green fluorescent protein as a selectable marker of retrovirally transduced hematopoietic progenitors.
Stem cells (Dayton, Ohio) 1999;17(4):226-32.
1998: Fan D S; Ogawa M; Fujimoto K I; Ikeguchi K; Ogasawara Y; Urabe M; Nishizawa M; Nakano I; Yoshida M; Nagatsu I; Ichinose H; Nagatsu T; Kurtzman G J; Ozawa K
Behavioral recovery in 6-hydroxydopamine-lesioned rats by cotransduction of striatum with tyrosine hydroxylase and aromatic L-amino acid decarboxylase genes using two separate adeno-associated virus vectors.
Human gene therapy 1998;9(17):2527-35.
1998: Muroi K; Handa K; Amemiya Y; Hakomori S; Ozawa K; Miura Y
Expression profiles of I and sialosyl-I antigens on blood cells: the sialosyl-I antigen is expressed along the monocytic differentiation.
Leukemia research 1998;22(11):1029-36.
1998: Terui Y; Ikeda M; Tomizuka H; Kasahara T; Ohtsuki T; Uwai M; Mori M; Itoh T; Tanaka M; Yamada M; Shimamura S; Ishizaka Y; Ikeda K; Ozawa K; Miura Y; Hatake K
Activated endothelial cells induce apoptosis in leukemic cells by endothelial interleukin-8.
Blood 1998;92(8):2672-80.
1998: Muroi K; Suda T; Kawano C; Amemiya Y; Eguchi M; Miura Y; Ozawa K
Analysis of C-KIT, TIE and HTK expression on leukemic cells using flow cytometry: a preliminary report.
Leukemia research 1998;22(9):827-30.
1998: Kokubun M; Kume A; Urabe M; Mano H; Okubo M; Kasukawa R; Kakizuka A; Ozawa K
Apoptosis-mediated regulation of recombinant human granulocyte colony-stimulating factor production by genetically engineered fibroblasts.
Gene therapy 1998;5(7):923-9.
1998: Kodaira H; Kume A; Ogasawara Y; Urabe M; Kitano K; Kakizuka A; Ozawa K
Fas and mutant estrogen receptor chimeric gene: a novel suicide vector for tamoxifen-inducible apoptosis.
Japanese journal of cancer research : Gann 1998;89(7):741-7.
1998: Maeda Y; Ikeda U; Shimpo M; Ueno S; Ogasawara Y; Urabe M; Kume A; Takizawa T; Saito T; Colosi P; Kurtzman G; Shimada K; Ozawa K
Efficient gene transfer into cardiac myocytes using adeno-associated virus (AAV) vectors.
Journal of molecular and cellular cardiology 1998;30(7):1341-8.
1998: Fan D; Ogawa M; Ikeguchi K; Fujimoto K; Urabe M; Kume A; Nishizawa M; Matsushita N; Kiuchi K; Ichinose H; Nagatsu T; Kurtzman G J; Nakano I; Ozawa K
Prevention of dopaminergic neuron death by adeno-associated virus vector-mediated GDNF gene transfer in rat mesencephalic cells in vitro.
Neuroscience letters 1998;248(1):61-4.
1998: Honda H; Oda H; Suzuki T; Takahashi T; Witte O N; Ozawa K; Ishikawa T; Yazaki Y; Hirai H
Development of acute lymphoblastic leukemia and myeloproliferative disorder in transgenic mice expressing p210bcr/abl: a novel transgenic model for human Ph1-positive leukemias.
Blood 1998;91(6):2067-75.
1998: Ogasawara Y; Urabe M; Ozawa K
The use of heterologous promoters for adeno-associated virus (AAV) protein expression in AAV vector production.
Microbiology and immunology 1998;42(3):177-85.
1997: Urabe M; Ozawa K
[Adeno-associated virus vectors and gene therapy]
Uirusu. Journal of virology 1997;47(2):221-30.
1997: Ozawa K
[Current status of gene therapy and viral vectors]
Uirusu. Journal of virology 1997;47(2):195-201.
1997: Nagamura-Inoue T; Tojo A; Ikebuchi K; Takahashi S; Ogura H; Shindoh E; Nagamura F; Uemura N; Watari K; Irie S; Setoyama M; Tajika K; Nakayama M; Nagayama H; Kobayashi Y; Shirafuji N; Sato N; Okamoto S; Ozawa K; Tani K; Asano S
Autologous bone marrow transplantation for patients with advanced chronic myelogenous leukemia.
International journal of hematology 1997;66(4):493-503.
1997: Ito K; Ueda Y; Kokubun M; Urabe M; Inaba T; Mano H; Hamada H; Kitamura T; Mizoguchi H; Sakata T; Hasegawa M; Ozawa K
Development of a novel selective amplifier gene for controllable expansion of transduced hematopoietic cells.
Blood 1997;90(10):3884-92.
1997: Urabe M; Hasumi Y; Ogasawara Y; Matsushita T; Kamoshita N; Nomoto A; Colosi P; Kurtzman G J; Tobita K; Ozawa K
A novel dicistronic AAV vector using a short IRES segment derived from hepatitis C virus genome.
Gene 1997;200(1-2):157-62.
1997: Surosky R T; Urabe M; Godwin S G; McQuiston S A; Kurtzman G J; Ozawa K; Natsoulis G
Adeno-associated virus Rep proteins target DNA sequences to a unique locus in the human genome.
Journal of virology 1997;71(10):7951-9.
1997: Maeda Y; Ikeda U; Ogasawara Y; Urabe M; Takizawa T; Saito T; Colosi P; Kurtzman G; Shimada K; Ozawa K
Gene transfer into vascular cells using adeno-associated virus (AAV) vectors.
Cardiovascular research 1997;35(3):514-21.
1997: Watari K; Ozawa K; Takahashi S; Tojo A; Tani K; Kamachi S; Asano S
Pharmacokinetic studies of intravenous glycosylated recombinant human granulocyte colony-stimulating factor in various hematological disorders: inverse correlation between the half-life and bone marrow myeloid cell pool.
International journal of hematology 1997;66(1):57-67.
1997: Kashiwada K; Nishida W; Hayashi K; Ozawa K; Yamanaka Y; Saga H; Yamashita T; Tohyama M; Shimada S; Sato K; Sobue K
Coordinate expression of alpha-tropomyosin and caldesmon isoforms in association with phenotypic modulation of smooth muscle cells.
The Journal of biological chemistry 1997;272(24):15396-404.
1997: Honda H; Ozawa K; Yazaki Y; Hirai H
Identification of PU.1 and Sp1 as essential transcriptional factors for the promoter activity of mouse tec gene.
Biochemical and biophysical research communications 1997;234(2):376-81.
1997: Oshima Y; Takahashi S; Nagayama H; Nishiwaki K; Kobayashi Y; Tojo A; Okamoto S; Tani K; Ozawa K; Wakabayashi T; Sato N; Kobayashi S; Nakamura K; Ohya Y; Nukina N; Kanazawa I; Asano S
Fatal GVHD demonstrating an involvement of respiratory muscle following donor leukocyte transfusion (DLT).
Bone marrow transplantation 1997;19(7):737-40.
1996: Nakayama M; Takahashi S; Inoue T; Nagamura F; Setoyama M; Ooi J; Takahashi T; Oshima Y; Miyamoto K; Uemura N; Shindo E; Tajika K; Yanagisawa K; Nagayama H; Okamoto S; Tojo A; Tani K; Ozawa K; Asano S; Wakabayashi T; Sato N; Ichinose Y; Toyama K; Saito H
[Bronchiolitis obliterans organizing pneumonia (BOOP) after allogeneic bone marrow transplantation]
[Rinsho ketsueki] The Japanese journal of clinical hematology 1996;37(11):1271-5.
1996: Kobayashi Y; Uehara S; Inamori K; Shirato R; Ozawa K; Sklar J; Asano S
Hemophagocytosis as a para-neoplastic syndrome in NK cell leukemia.
International journal of hematology 1996;64(2):135-42.
1996: Honda H; Yamashita Y; Ozawa K; Mano H
Cloning and characterization of mouse tec promoter.
Biochemical and biophysical research communications 1996;223(2):422-6.
1996: Tsuruta T; Tani K; Shimane M; Ozawa K; Takahashi S; Tsuchimoto D; Takahashi K; Nagata S; Sato N; Asano S
Effects of myeloid cell growth factors on alkaline phosphatase, myeloperoxidase, defensin and granulocyte colony-stimulating factor receptor mRNA expression in haemopoietic cells of normal individuals and myeloid disorders.
British journal of haematology 1996;92(1):9-22.
1996: Tojo A; Oshima Y; Ozawa K; Niho Y; Asano S
In vitro model of toxin therapy targeted against murine myeloid leukemia cells.
Cancer chemotherapy and pharmacology 1996;38 Suppl():S37-9.
1995: Tani K; Lin T; Hibino H; Takahashi K; Nakazaki Y; Takahashi S; Nagayama H; Ozawa K; Saitoh I; Mulligan R
Transduction of LacZ gene into leukemia cells using viral vectors of retrovirus and adenovirus.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9 Suppl 1():S64-5.
1995: Kobayashi Y; Hayashi Y; Ozawa K; Asano S
HRX gene rearrangement in secondary acute lymphoblastic leukemia.
Leukemia & lymphoma 1995;17(5-6):391-9.
1995: Okumura K; Nogami M; Taguchi H; Dean F B; Chen M; Pan Z Q; Hurwitz J; Shiratori A; Murakami Y; Ozawa K
Assignment of the 36.5-kDa (RFC5), 37-kDa (RFC4), 38-kDa (RFC3), and 40-kDa (RFC2) subunit genes of human replication factor C to chromosome bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23.
Genomics 1995;25(1):274-8.
1994: Seki M; Miyazawa H; Tada S; Yanagisawa J; Yamaoka T; Hoshino S; Ozawa K; Eki T; Nogami M; Okumura K
Molecular cloning of cDNA encoding human DNA helicase Q1 which has homology to Escherichia coli Rec Q helicase and localization of the gene at chromosome 12p12.
Nucleic acids research 1994;22(22):4566-73.
1994: Watari K; Ozawa K; Tajika K; Tojo A; Tani K; Kamachi S; Harigaya K; Takahashi T; Sekiguchi S; Nagata S
Production of human granulocyte colony stimulating factor by various kinds of stromal cells in vitro detected by enzyme immunoassay and in situ hybridization.
Stem cells (Dayton, Ohio) 1994;12(4):416-23.
1994: Yoshikubo T; Ozawa K; Takahashi K; Nishikawa M; Horiuchi N; Tojo A; Tani K; Kodama H; Asano S
Adhesion of NFS-60 myeloid leukemia cells to MC3T3-G2/PA6 stromal cells induces granulocyte colony-stimulating factor production.
Blood 1994;84(2):415-20.
1994: Aoki Y; Tani K; Takahashi K; Fukushima M; Ozawa K; Asano S
Regulation of recombinant human granulocyte colony-stimulation factor production using herpes simplex virus 1 thymidine kinase gene.
Biochemical and biophysical research communications 1994;200(3):1245-51.
1994: Tani K; Yoshikubo T; Ikebuchi K; Takahashi K; Tsuchiya T; Takahashi S; Shimane M; Ogura H; Tojo A; Ozawa K
Retrovirus-mediated gene transfer of human pyruvate kinase (PK) cDNA into murine hematopoietic cells: implications for gene therapy of human PK deficiency.
Blood 1994;83(8):2305-10.
1994: Shimane M; Tani K; Maruyama K; Takahashi S; Ozawa K; Asano S
Molecular cloning and characterization of G-CSF induced gene cDNA.
Biochemical and biophysical research communications 1994;199(1):26-32.
1993: Bakic M; Ozawa K; Uemura N; Nishikawa M; Tojo A; Takahashi K; Tani K; Zaike Y; Ikebuchi K; Asano S
Sustained c-kit expression in a human erythroleukemia cell line (HEL) after megakaryocytic differentiation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA).
Leukemia research 1993;17(12):1079-82.
1993: Uemura N; Ozawa K; Takahashi K; Tojo A; Tani K; Harigaya K; Suzu S; Motoyoshi K; Matsuda H; Yagita H
Binding of membrane-anchored macrophage colony-stimulating factor (M-CSF) to its receptor mediates specific adhesion between stromal cells and M-CSF receptor-bearing hematopoietic cells.
Blood 1993;82(9):2634-40.
1993: Ozawa K; Dean F B; Chen M; Lee S H; Shiratori A; Murakami Y; Sakakura T; Hurwitz J; Eki T
Mapping of the 70 kDa, 34 kDa, and 11 kDa subunit genes of the human multimeric single-stranded DNA binding protein (hSSB/RPA) to chromosome bands 17p13, 1p35-p36.1, and 7p21-p22.
Cell structure and function 1993;18(4):221-30.
1993: Tani K; Ozawa K; Ogura H; Takahashi S; Takahashi K; Tsuruta T; Okano A; Akiyama Y; Yoshikubo T; Shimane M
The production of granulocyte colony-stimulating factor and interleukin 6 by human bone marrow stromal cells in aplastic anemia.
The Tohoku journal of experimental medicine 1993;169(4):325-34.
1993: Nishikawa M; Ozawa K; Tojo A; Yoshikubo T; Okano A; Tani K; Ikebuchi K; Nakauchi H; Asano S
Changes in hematopoiesis-supporting ability of C3H10T1/2 mouse embryo fibroblasts during differentiation.
Blood 1993;81(5):1184-92.
1993: Takahashi T; Ozawa K; Takahashi K; Okuno Y; Takahashi T; Muto Y; Takaku F; Asano S
DNA replication of parvovirus B 19 in a human erythroid leukemia cell line (JK-1) in vitro.
Archives of virology 1993;131(1-2):201-8.
1992: Uemura N; Ozawa K; Tojo A; Takahashi K; Okano A; Karasuyama H; Tani K; Asano S
Acquisition of interleukin-3 independence in FDC-P2 cells after transfection with the activated c-H-ras gene using a bovine papillomavirus-based plasmid vector.
Blood 1992;80(12):3198-204.
1992: Tsurumi H; Tani K; Tsuruta T; Shirato R; Matsudaira T; Tojo A; Wada C; Uchida H; Ozawa K; Asano S
Adult T-cell leukemia developing during immunosuppressive treatment in a renal transplant recipient.
American journal of hematology 1992;41(4):292-4.
1992: Ozawa K
[Genome structure and gene products of parvoviruses]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1992;37(14 Suppl):2348-54.
1992: Tsurumi H; Tani K; Tajika K; Irie S; Kobayashi Y; Tojo A; Okamoto S; Ozawa K; Moriwaki H; Muto Y
Spontaneous bacterial peritonitis due to Clostridium perfringens in a patient with liver cirrhosis and pure red cell aplasia.
Gastroenterologia Japonica 1992;27(5):662-7.
1992: Nishikawa M; Tojo A; Ikebuchi K; Katayama K; Fujii N; Ozawa K; Asano S
Deletion mutagenesis of stem cell factor defines the C-terminal sequences essential for its biological activity.
Biochemical and biophysical research communications 1992;188(1):292-7.
1992: Matsudaira T; Kodo H; Okamoto S; Tani K; Tojo A; Ozawa K; Asano K; Asano S
The alloantigen-specific immunosuppressive activity of estradiol-chlorambucil conjugate (KM2210) and its beneficial effect on allogeneic bone marrow transplantation in mice.
Transplantation 1992;54(4):676-81.
1992: Inoue T; Tojo A; Tsuchimoto D; Okamoto S; Ogura H; Tani K; Ozawa K; Shibuya M; Asano S
Possible correlation between fusion pattern of BCR/ABL mRNA and clinical response to alpha-interferon in chronic myelogenous leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1992;6(9):948-51.
1992: Irie S; Ogura H; Okamoto S; Tojo A; Tani K; Ikebuchi K; Satoh N; Ozawa K; Asano S
Case report: alternation therapy with antileukemic agents and recombinant human granulocyte colony-stimulating factor for RAEB in transformation.
The American journal of the medical sciences 1992;303(5):316-8.
1992: Ozawa K; Watari K; Tsuruta T; Takahashi S; Ogura H; Yoshikubo T; Nishikawa M; Shimane M; Okamoto S; Tojo A
Pathophysiological roles of G-CSF.
Journal of nutritional science and vitaminology 1992;Spec No():345-8.
1991: Ozawa K
[CSFs and regulatory mechanisms of their expression]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):1132-9.
1991: Asano S; Ogura H; Tani K; Inoue T; Tojo A; Ozawa K
Several new approaches to improvement of alpha interferon therapy in chronic myelogenous leukaemia.
European journal of cancer (Oxford, England : 1990) 1991;27 Suppl 4():S21-5.
1990: Ieki R; Kudoh S; Kimura H; Ozawa K; Asano S; Takaku F
Human granulocyte colony formation in serum-free cultures stimulated with purified recombinant granulocyte colony-stimulating factor.
Experimental hematology 1990;18(8):883-7.
1990: Ogura H; Tani K; Ozawa K; Nagata S; Asano S; Takaku F
Implantation of genetically manipulated fibroblasts into mice as antitumor alpha-interferon therapy.
Cancer research 1990;50(16):5102-6.
1990: Ogura H; Tani K; Kozai Y; Watari K; Kodo H; Ozawa K; Asano S; Takaku F
Effect of interferon-alpha in patients with chronic myelogenous leukemia in the accelerated phase: cytogenetic and molecular studies.
Japanese journal of cancer research : Gann 1990;81(6-7):682-6.
1990: Asano S; Okano A; Ozawa K; Nakahata T; Ishibashi T; Koike K; Kimura H; Tanioka Y; Shibuya A; Hirano T
In vivo effects of recombinant human interleukin-6 in primates: stimulated production of platelets.
Blood 1990;75(8):1602-5.
1990: Takahashi T; Ozawa K; Takahashi K; Asano S; Takaku F
Susceptibility of human erythropoietic cells to B19 parvovirus in vitro increases with differentiation.
Blood 1990;75(3):603-10.
1990: Shirafuji N; Matsuda S; Ogura H; Tani K; Kodo H; Ozawa K; Nagata S; Asano S; Takaku F
Granulocyte colony-stimulating factor stimulates human mature neutrophilic granulocytes to produce interferon-alpha.
Blood 1990;75(1):17-9.
1990: Tani K; Ozawa K; Ogura H; Shimane M; Shirafuji N; Tsuruta T; Yokota J; Nagata S; Ueyama Y; Takaku F
Expression of granulocyte and granulocyte-macrophage colony-stimulating factors by human non-hematopoietic tumor cells.
Growth factors (Chur, Switzerland) 1990;3(4):325-31.
1989: Tani K; Asano S; Ozawa K; Takaku F
A StuI polymorphism in the human granulocyte colony-stimulating factor gene.
Nucleic acids research 1989;17(18):7544.
1989: Tani K; Ozawa K; Ogura H; Takahashi T; Okano A; Watari K; Matsudaira T; Tajika K; Karasuyama H; Nagata S
Implantation of fibroblasts transfected with human granulocyte colony-stimulating factor cDNA into mice as a model of cytokine-supplement gene therapy.
Blood 1989;74(4):1274-80.
1989: Kobayashi Y; Okabe T; Ozawa K; Chiba S; Hino M; Miyazono K; Urabe A; Takaku F
Treatment of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor: a preliminary report.
The American journal of medicine 1989;86(2):178-82.
1989: Watari K; Asano S; Shirafuji N; Kodo H; Ozawa K; Takaku F; Kamachi S
Serum granulocyte colony-stimulating factor levels in healthy volunteers and patients with various disorders as estimated by enzyme immunoassay.
Blood 1989;73(1):117-22.

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