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Maurizio Pacifici
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Anatomy
Chemicals & Drugs
Physiology
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Network (preview)
39
Koyama, Eiki
25
Iwamoto, Masahiro
19
Enomoto-Iwamoto, Motomi
13
Adams, Sherrill
11
Leboy, Phoebe
10
Shapiro, Irving
9
Shimo, Tsuyoshi
8
Kirsch, Thorsten
7
Nah, Hyun-Duck
6
Noji, Sumihare
6
Tamamura, Yoshihiro
6
Wu, Changshan
5
Billings, Paul
5
Gentili, Chiara
4
Abrams, William
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All Publications
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2009: Yuasa Takahito; Kondo Naoki; Yasuhara Rika; Shimono Kengo; Mackem Susan; Pacifici Maurizio; Iwamoto Masahiro; Enomoto-Iwamoto Motomi
Transient activation of Wnt/{beta}-catenin signaling induces abnormal growth plate closure and articular cartilage thickening in postnatal mice.
The American journal of pathology 2009;175(5):1993-2003.
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2009: Ochiai T; Nagayama M; Nakamura T; Morrison T; Pilchak D; Kondo N; Hasegawa H; Song B; Serra R; Pacifici M; Koyama E
Roles of the primary cilium component Polaris in synchondrosis development.
Journal of dental research 2009;88(6):545-50.
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2009: Williams Julie A; Kondo Naoki; Okabe Takahiro; Takeshita Nobuo; Pilchak Diane M; Koyama Eiki; Ochiai Takanaga; Jensen Deborah; Chu Mon-Li; Kane Maureen A; Napoli Joseph L; Enomoto-Iwamoto Motomi; Ghyselinck Norbert; Chambon Pierre; Pacifici Maurizio; Iwamoto Masahiro
Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.
Developmental biology 2009;328(2):315-27.
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2008: Koyama Eiki; Shibukawa Yoshihiro; Nagayama Motohiko; Sugito Hiroki; Young Blanche; Yuasa Takahito; Okabe Takahiro; Ochiai Takanaga; Kamiya Nobuhiko; Rountree Ryan B; Kingsley David M; Iwamoto Masahiro; Enomoto-Iwamoto Motomi; Pacifici Maurizio
A distinct cohort of progenitor cells participates in synovial joint and articular cartilage formation during mouse limb skeletogenesis.
Developmental biology 2008;316(1):62-73.
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2008: Nagayama M; Iwamoto M; Hargett A; Kamiya N; Tamamura Y; Young B; Morrison T; Takeuchi H; Pacifici M; Enomoto-Iwamoto M; Koyama E
Wnt/beta-catenin signaling regulates cranial base development and growth.
Journal of dental research 2008;87(3):244-9.
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2007: Koyama Eiki; Ochiai Takanaga; Rountree Ryan B; Kingsley David M; Enomoto-Iwamoto Motomi; Iwamoto Masahiro; Pacifici Maurizio
Synovial joint formation during mouse limb skeletogenesis: roles of Indian hedgehog signaling.
Annals of the New York Academy of Sciences 2007;1116():100-12.
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2007: Koyama Eiki; Young Blanche; Nagayama Motohiko; Shibukawa Yoshihiro; Enomoto-Iwamoto Motomi; Iwamoto Masahiro; Maeda Yukiko; Lanske Beate; Song Buer; Serra Rosa; Pacifici Maurizio
Conditional Kif3a ablation causes abnormal hedgehog signaling topography, growth plate dysfunction, and excessive bone and cartilage formation during mouse skeletogenesis.
Development (Cambridge, England) 2007;134(11):2159-69.
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2007: Iwamoto Masahiro; Tamamura Yoshihiro; Koyama Eiki; Komori Toshihisa; Takeshita Nobuo; Williams Julie A; Nakamura Takashi; Enomoto-Iwamoto Motomi; Pacifici Maurizio
Transcription factor ERG and joint and articular cartilage formation during mouse limb and spine skeletogenesis.
Developmental biology 2007;305(1):40-51.
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2007: Shibukawa Yoshihiro; Young Blanche; Wu Changshan; Yamada Satoru; Long Fanxin; Pacifici Maurizio; Koyama Eiki
Temporomandibular joint formation and condyle growth require Indian hedgehog signaling.
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(2):426-34.
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2006: Young Blanche; Minugh-Purvis Nancy; Shimo Tsuyoshi; St-Jacques Benoit; Iwamoto Masahiro; Enomoto-Iwamoto Motomi; Koyama Eiki; Pacifici Maurizio
Indian and sonic hedgehogs regulate synchondrosis growth plate and cranial base development and function.
Developmental biology 2006;299(1):272-82.
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2006: Pacifici Maurizio; Koyama Eiki; Shibukawa Yoshihiro; Wu Changshan; Tamamura Yoshihiro; Enomoto-Iwamoto Motomi; Iwamoto Masahiro
Cellular and molecular mechanisms of synovial joint and articular cartilage formation.
Annals of the New York Academy of Sciences 2006;1068():74-86.
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2005: Pacifici Maurizio; Koyama Eiki; Iwamoto Masahiro
Mechanisms of synovial joint and articular cartilage formation: recent advances, but many lingering mysteries.
Birth defects research. Part C, Embryo today : reviews 2005;75(3):237-48.
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2005: Shimo Tsuyoshi; Koyama Eiki; Sugito Hiroki; Wu Changshan; Shimo Satoko; Pacifici Maurizio
Retinoid signaling regulates CTGF expression in hypertrophic chondrocytes with differential involvement of MAP kinases.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(5):867-77.
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2005: Tamamura Yoshihiro; Otani Tomohiro; Kanatani Naoko; Koyama Eiki; Kitagaki Jirota; Komori Toshihisa; Yamada Yoshihiko; Costantini Frank; Wakisaka Satoshi; Pacifici Maurizio; Iwamoto Masahiro; Enomoto-Iwamoto Motomi
Developmental regulation of Wnt/beta-catenin signals is required for growth plate assembly, cartilage integrity, and endochondral ossification.
The Journal of biological chemistry 2005;280(19):19185-95.
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2005: Iwamoto Masahiro; Koyama Eiki; Enomoto-Iwamoto Motomi; Pacifici Maurizio
The balancing act of transcription factors C-1-1 and Runx2 in articular cartilage development.
Biochemical and biophysical research communications 2005;328(3):777-82.
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2005: Fakhry Ali; Ratisoontorn Chootima; Vedhachalam Charulatha; Salhab Imad; Koyama Eiki; Leboy Phoeby; Pacifici Maurizio; Kirschner Richard E; Nah Hyun-Duck
Effects of FGF-2/-9 in calvarial bone cell cultures: differentiation stage-dependent mitogenic effect, inverse regulation of BMP-2 and noggin, and enhancement of osteogenic potential.
Bone 2005;36(2):254-66.
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2005: Pacifici Maurizio; Shimo Tsuyoshi; Gentili Chiara; Kirsch Thorsten; Freeman Theresa A; Enomoto-Iwamoto Motomi; Iwamoto Masahiro; Koyama Eiki
Syndecan-3: a cell-surface heparan sulfate proteoglycan important for chondrocyte proliferation and function during limb skeletogenesis.
Journal of bone and mineral metabolism 2005;23(3):191-9.
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2004: Shimo Tsuyoshi; Kanyama Manabu; Wu Changshan; Sugito Hiroki; Billings Paul C; Abrams William R; Rosenbloom Joel; Iwamoto Masahiro; Pacifici Maurizio; Koyama Eiki
Expression and roles of connective tissue growth factor in Meckel's cartilage development.
Developmental dynamics : an official publication of the American Association of Anatomists 2004;231(1):136-47.
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2004: Shimo Tsuyoshi; Gentili Chiara; Iwamoto Masahiro; Wu Changshan; Koyama Eiki; Pacifici Maurizio
Indian hedgehog and syndecans-3 coregulate chondrocyte proliferation and function during chick limb skeletogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists 2004;229(3):607-17.
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2003: Koyama Eiki; Wu Changshan; Shimo Tsuyoshi; Pacifici Maurizio
Chick limbs with mouse teeth: an effective in vivo culture system for tooth germ development and analysis.
Developmental dynamics : an official publication of the American Association of Anatomists 2003;226(1):149-54.
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2003: Iwamoto M; Kitagaki J; Tamamura Y; Gentili C; Koyama E; Enomoto H; Komori T; Pacifici M; Enomoto-Iwamoto M
Runx2 expression and action in chondrocytes are regulated by retinoid signaling and parathyroid hormone-related peptide (PTHrP).
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2003;11(1):6-15.
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2003: Lovinescu Irina; Koyama E; Pacifici M
Roles of FGF-10 on the development of diathrodial limb joints.
The Penn dental journal 2003;103():5, 9.
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2003: Wu Changshan; Shimo Tsuyoshi; Liu Mufei; Pacifici Maurizio; Koyama Eiki
Sonic hedgehog functions as a mitogen during bell stage of odontogenesis.
Connective tissue research 2003;44 Suppl 1():92-6.
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2002: Enomoto-Iwamoto Motomi; Kitagaki Jirouta; Koyama Eiki; Tamamura Yoshihiro; Wu Changshan; Kanatani Naoko; Koike Tatsuya; Okada Hiroshi; Komori Toshihisa; Yoneda Toshiyuki; Church Vicki; Francis-West Philippa H; Kurisu Kojiro; Nohno Tsutomu; Pacifici Maurizio; Iwamoto Masahiro
The Wnt antagonist Frzb-1 regulates chondrocyte maturation and long bone development during limb skeletogenesis.
Developmental biology 2002;251(1):142-56.
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2002: Kirsch Thorsten; Koyama Eiki; Liu Mufei; Golub Ellis E; Pacifici Maurizio
Syndecan-3 is a selective regulator of chondrocyte proliferation.
The Journal of biological chemistry 2002;277(44):42171-7.
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2002: Shimo Tsuyoshi; Wu Changshan; Billings Paul C; Piddington Ronald; Rosenbloom Joel; Pacifici Maurizio; Koyama Eiki
Expression, gene regulation, and roles of Fisp12/CTGF in developing tooth germs.
Developmental dynamics : an official publication of the American Association of Anatomists 2002;224(3):267-78.
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2002: Yin Melinda; Gentili Chiara; Koyama Eiki; Zasloff Michael; Pacifici Maurizio
Antiangiogenic treatment delays chondrocyte maturation and bone formation during limb skeletogenesis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(1):56-65.
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2001: Dangelo M; Sarment D P; Billings P C; Pacifici M
Activation of transforming growth factor beta in chondrocytes undergoing endochondral ossification.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(12):2339-47.
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2001: Yin M; Pacifici M
Vascular regression is required for mesenchymal condensation and chondrogenesis in the developing limb.
Developmental dynamics : an official publication of the American Association of Anatomists 2001;222(3):522-33.
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2001: Koyama E; Wu C; Shimo T; Iwamoto M; Ohmori T; Kurisu K; Ookura T; Bashir M M; Abrams W R; Tucker T; Pacifici M
Development of stratum intermedium and its role as a Sonic hedgehog-signaling structure during odontogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists 2001;222(2):178-91.
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2001: D'Angelo M; Billings P C; Pacifici M; Leboy P S; Kirsch T
Authentic matrix vesicles contain active metalloproteases (MMP). a role for matrix vesicle-associated MMP-13 in activation of transforming growth factor-beta.
The Journal of biological chemistry 2001;276(14):11347-53.
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2001: Iwamoto M; Higuchi Y; Enomoto-Iwamoto M; Kurisu K; Koyama E; Yeh H; Rosenbloom J; Pacifici M
The role of ERG (ets related gene) in cartilage development.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9 Suppl A():S41-7.
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2000: Enomoto-Iwamoto M; Nakamura T; Aikawa T; Higuchi Y; Yuasa T; Yamaguchi A; Nohno T; Noji S; Matsuya T; Kurisu K; Koyama E; Pacifici M; Iwamoto M
Hedgehog proteins stimulate chondrogenic cell differentiation and cartilage formation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(9):1659-68.
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2000: Iwamoto M; Higuchi Y; Koyama E; Enomoto-Iwamoto M; Kurisu K; Yeh H; Abrams W R; Rosenbloom J; Pacifici M
Transcription factor ERG variants and functional diversification of chondrocytes during limb long bone development.
The Journal of cell biology 2000;150(1):27-40.
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2000: D'Angelo M; Yan Z; Nooreyazdan M; Pacifici M; Sarment D S; Billings P C; Leboy P S
MMP-13 is induced during chondrocyte hypertrophy.
Journal of cellular biochemistry 2000;77(4):678-93.
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2000: Nah H D; Pacifici M; Gerstenfeld L C; Adams S L; Kirsch T
Transient chondrogenic phase in the intramembranous pathway during normal skeletal development.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(3):522-33.
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2000: Pacifici M; Koyama E; Iwamoto M; Gentili C
Development of articular cartilage: what do we know about it and how may it occur?
Connective tissue research 2000;41(3):175-84.
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1999: Yagami K; Suh J Y; Enomoto-Iwamoto M; Koyama E; Abrams W R; Shapiro I M; Pacifici M; Iwamoto M
Matrix GLA protein is a developmental regulator of chondrocyte mineralization and, when constitutively expressed, blocks endochondral and intramembranous ossification in the limb.
The Journal of cell biology 1999;147(5):1097-108.
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1999: Koyama E; Golden E B; Kirsch T; Adams S L; Chandraratna R A; Michaille J J; Pacifici M
Retinoid signaling is required for chondrocyte maturation and endochondral bone formation during limb skeletogenesis.
Developmental biology 1999;208(2):375-91.
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1997: D'Angelo M; Pacifici M
Articular chondrocytes produce factors that inhibit maturation of sternal chondrocytes in serum-free agarose cultures: a TGF-beta independent process.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(9):1368-77.
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1997: Nakamura T; Aikawa T; Iwamoto-Enomoto M; Iwamoto M; Higuchi Y; Pacifici M; Kinto N; Yamaguchi A; Noji S; Kurisu K; Matsuya T;
Induction of osteogenic differentiation by hedgehog proteins.
Biochemical and biophysical research communications 1997;237(2):465-9.
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1997: Enomoto-Iwamoto M; Iwamoto M; Nakashima K; Mukudai Y; Boettiger D; Pacifici M; Kurisu K; Suzuki F
Involvement of alpha5beta1 integrin in matrix interactions and proliferation of chondrocytes.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(7):1124-32.
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1997: Kirsch T; Nah H D; Shapiro I M; Pacifici M
Regulated production of mineralization-competent matrix vesicles in hypertrophic chondrocytes.
The Journal of cell biology 1997;137(5):1149-60.
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1997: Kirsch T; Nah H D; Demuth D R; Harrison G; Golub E E; Adams S L; Pacifici M
Annexin V-mediated calcium flux across membranes is dependent on the lipid composition: implications for cartilage mineralization.
Biochemistry 1997;36(11):3359-67.
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1996: Shimazu A; Nah H D; Kirsch T; Koyama E; Leatherman J L; Golden E B; Kosher R A; Pacifici M
Syndecan-3 and the control of chondrocyte proliferation during endochondral ossification.
Experimental cell research 1996;229(1):126-36.
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1996: Koyama E; Leatherman J L; Noji S; Pacifici M
Early chick limb cartilaginous elements possess polarizing activity and express hedgehog-related morphogenetic factors.
Developmental dynamics : an official publication of the American Association of Anatomists 1996;207(3):344-54.
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1996: Koyama E; Leatherman J L; Noji S; Pacifici M
Polarizing activity in early limb cartilaginous condensations.
Annals of the New York Academy of Sciences 1996;785():281-3.
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1996: Koyama E; Yamaai T; Iseki S; Ohuchi H; Nohno T; Yoshioka H; Hayashi Y; Leatherman J L; Golden E B; Noji S; Pacifici M
Polarizing activity, Sonic hedgehog, and tooth development in embryonic and postnatal mouse.
Developmental dynamics : an official publication of the American Association of Anatomists 1996;206(1):59-72.
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1996: Koyama E; Shimazu A; Leatherman J L; Golden E B; Nah H D; Pacifici M
Expression of syndecan-3 and tenascin-C: possible involvement in periosteum development.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1996;14(3):403-12.
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1995: Pacifici M
Tenascin-C and the development of articular cartilage.
Matrix biology : journal of the International Society for Matrix Biology 1995;14(9):689-98.
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1995: Hatori M; Teixeira C C; Debolt K; Pacifici M; Shapiro I M
Adenine nucleotide metabolism by chondrocytes in vitro: role of ATP in chondrocyte maturation and matrix mineralization.
Journal of cellular physiology 1995;165(3):468-74.
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1995: Iwamoto M; Shimazu A; Pacifici M
Regulation of chondrocyte maturation by fibroblast growth factor-2 and parathyroid hormone.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1995;13(6):838-45.
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1995: Koyama E; Leatherman J L; Shimazu A; Nah H D; Pacifici M
Syndecan-3, tenascin-C, and the development of cartilaginous skeletal elements and joints in chick limbs.
Developmental dynamics : an official publication of the American Association of Anatomists 1995;203(2):152-62.
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1995: Teixeira C C; Hatori M; Leboy P S; Pacifici M; Shapiro I M
A rapid and ultrasensitive method for measurement of DNA, calcium and protein content, and alkaline phosphatase activity of chondrocyte cultures.
Calcified tissue international 1995;56(3):252-6.
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1994: Shapiro I M; Debolt K; Hatori M; Iwamoto M; Pacifici M
Retinoic acid induces a shift in the energetic state of hypertrophic chondrocytes.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(8):1229-37.
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1994: Iwamoto M; Yagami K; Shapiro I M; Leboy P S; Adams S L; Pacifici M
Retinoic acid is a major regulator of chondrocyte maturation and matrix mineralization.
Microscopy research and technique 1994;28(6):483-91.
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1993: Pacifici M; Iwamoto M; Golden E B; Leatherman J L; Lee Y S; Chuong C M
Tenascin is associated with articular cartilage development.
Developmental dynamics : an official publication of the American Association of Anatomists 1993;198(2):123-34.
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1993: Iwamoto M; Shapiro I M; Yagami K; Boskey A L; Leboy P S; Adams S L; Pacifici M
Retinoic acid induces rapid mineralization and expression of mineralization-related genes in chondrocytes.
Experimental cell research 1993;207(2):413-20.
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1993: Lu Valle P; Iwamoto M; Fanning P; Pacifici M; Olsen B R
Multiple negative elements in a gene that codes for an extracellular matrix protein, collagen X, restrict expression to hypertrophic chondrocytes.
The Journal of cell biology 1993;121(5):1173-9.
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1993: Iwamoto M; Yagami K; Lu Valle P; Olsen B R; Petropoulos C J; Ewert D L; Pacifici M
Expression and role of c-myc in chondrocytes undergoing endochondral ossification.
The Journal of biological chemistry 1993;268(13):9645-52.
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1993: Iwamoto M; Golden E B; Adams S L; Noji S; Pacifici M
Responsiveness to retinoic acid changes during chondrocyte maturation.
Experimental cell research 1993;205(2):213-24.
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1991: Shapiro I M; Leboy P S; Tokuoka T; Forbes E; DeBolt K; Adams S L; Pacifici M
Ascorbic acid regulates multiple metabolic activities of cartilage cells.
The American journal of clinical nutrition 1991;54(6 Suppl):1209S-1213S.
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1991: Pacifici M; Golden E B; Iwamoto M; Adams S L
Retinoic acid treatment induces type X collagen gene expression in cultured chick chondrocytes.
Experimental cell research 1991;195(1):38-46.
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1991: Adams S L; Pallante K M; Niu Z; Leboy P S; Golden E B; Pacifici M
Rapid induction of type X collagen gene expression in cultured chick vertebral chondrocytes.
Experimental cell research 1991;193(1):190-7.
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1991: Pacifici M; Golden E B; Adams S L; Shapiro I M
Cell hypertrophy and type X collagen synthesis in cultured articular chondrocytes.
Experimental cell research 1991;192(1):266-70.
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1990: Oettinger H F; Pacifici M
Type X collagen gene expression is transiently up-regulated by retinoic acid treatment in chick chondrocyte cultures.
Experimental cell research 1990;191(2):292-8.
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1990: Pacifici M; Oshima O; Fisher L W; Young M F; Shapiro I M; Leboy P S
Changes in osteonectin distribution and levels are associated with mineralization of the chicken tibial growth cartilage.
Calcified tissue international 1990;47(1):51-61.
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1990: Pacifici M; Golden E B; Oshima O; Shapiro I M; Leboy P S; Adams S L
Hypertrophic chondrocytes. The terminal stage of differentiation in the chondrogenic cell lineage?
Annals of the New York Academy of Sciences 1990;599():45-57.
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1990: Silverton S F; Pacifici M; Haselgrove J C; Colodny S H; Forster R E
Two-dimensional model of tissue oxygen gradients in avian growth cartilage.
Advances in experimental medicine and biology 1990;277():759-65.
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1989: Leboy P S; Vaias L; Uschmann B; Golub E; Adams S L; Pacifici M
Ascorbic acid induces alkaline phosphatase, type X collagen, and calcium deposition in cultured chick chondrocytes.
The Journal of biological chemistry 1989;264(29):17281-6.
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1989: Adams S L; Pallante K M; Pacifici M
Effects of cell shape on type X collagen gene expression in hypertrophic chondrocytes.
Connective tissue research 1989;20(1-4):223-32.
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1988: Pacifici M; Iozzo R V
Remodeling of the rough endoplasmic reticulum during stimulation of procollagen secretion by ascorbic acid in cultured chondrocytes. A biochemical and morphological study.
The Journal of biological chemistry 1988;263(5):2483-92.
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1987: Adams S L; Pacifici M; Boettiger D; Pallante K M
Modulation of fibronectin gene expression in chondrocytes by viral transformation and substrate attachment.
The Journal of cell biology 1987;105(1):483-8.
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1985: Pacifici M; Oettinger H F
Stable phenotypic expression by chick chondroblasts in long-term suspension cultures as determined by proteoglycan analysis.
Experimental cell research 1985;161(2):381-92.
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1985: Oettinger H F; Thal G; Sasse J; Holtzer H; Pacifici M
Immunological analysis of chick notochord and cartilage matrix development with antisera to cartilage matrix macromolecules.
Developmental biology 1985;109(1):63-71.
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1983: Pacifici M; Soltesz R; Thal G; Shanley D J; Boettiger D; Holtzer H
Immunological characterization of the major chick cartilage proteoglycan and its intracellular localization in cultured chondroblasts: a comparison with Type II procollagen.
The Journal of cell biology 1983;97(6):1724-36.
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1983: Boettiger D; Soltesz R; Holtzer H; Pacifici M
Infection of chick limb bud presumptive chondroblasts by a temperature-sensitive mutant of Rous sarcoma virus and the reversible inhibition of their terminal differentiation in culture.
Molecular and cellular biology 1983;3(8):1518-26.
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1983: Shanley D J; Cossu G; Boettiger D; Holtzer H; Pacifici M
Transformation by Rous sarcoma virus induces similar patterns of glycosaminoglycan synthesis in chick embryo skin fibroblasts and vertebral chondroblasts.
The Journal of biological chemistry 1983;258(2):810-6.
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