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Douglas Paddon-Jones

Research Profile

Anatomy

Muscle, Skeletal

Chemicals & Drugs

Physiology

Disorders

Muscular Atrophy

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Publications

TOP 3
Douglas Paddon-Jones
Perspective: Exercise and protein supplementation in frail elders.
Shanon L Casperson; Susan J Hewlings; Melinda Sheffield-Moore; Douglas Paddon-Jones
Leucine supplementation chronically improves muscle protein synthesis in older adults consuming the RDA for protein.
Micah J Drummond; Christopher S Fry; David M Gundermann; Melissa M Markofski; Douglas Paddon-Jones; Blake B Rasmussen; Paul T Reidy; Kyle L Timmerman; Jared M Dickinson; Dillon K Walker; Elena Volpi
Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults.

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All Publications

2013: Douglas Paddon-Jones
Perspective: Exercise and protein supplementation in frail elders.
Journal of the American Medical Directors Association 2013;14(1):73-4.
2012: Shanon L Casperson; Susan J Hewlings; Melinda Sheffield-Moore; Douglas Paddon-Jones
Leucine supplementation chronically improves muscle protein synthesis in older adults consuming the RDA for protein.
Clinical nutrition (Edinburgh, Scotland) 2012;31(4):512-9.
2012: Micah J Drummond; Christopher S Fry; David M Gundermann; Melissa M Markofski; Douglas Paddon-Jones; Blake B Rasmussen; Paul T Reidy; Kyle L Timmerman; Jared M Dickinson; Dillon K Walker; Elena Volpi
Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults.
American journal of physiology. Endocrinology and metabolism 2012;302(9):E1113-22.
2011: Melinda Sheffield-Moore; Shanon L Casperson; E Lichar Dillon; William J Durham; Charles Gilkison; James J Grady; Douglas Paddon-Jones; Randall J Urban
A randomized pilot study of monthly cycled testosterone replacement or continuous testosterone replacement versus placebo in older men.
The Journal of clinical endocrinology and metabolism 2011;96(11):E1831-7.
2010: William J Durham; Shanon L Casperson; Edgar L Dillon; Michelle A Keske; Douglas Paddon-Jones; Arthur P Sanford; Robert C Hickner; James J Grady; Melinda Sheffield-Moore
Age-related anabolic resistance after endurance-type exercise in healthy humans.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(10):4117-27.
2010: Melanie G Cree; Douglas Paddon-Jones; Bradley R Newcomer; Ola Ronsen; Asle Aarsland; Robert R Wolfe; Arny Ferrando
Twenty-eight-day bed rest with hypercortisolemia induces peripheral insulin resistance and increases intramuscular triglycerides.
Metabolism: clinical and experimental 2010;59(5):703-10.
2010: Arny Ferrando; Douglas Paddon-Jones; Nicholas P Hays; Patrick Kortebein; Ola Ronsen; Rick H Williams; Ashley McComb; T Brock Symons; Robert R Wolfe; William Evans
EAA supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly.
Clinical nutrition (Edinburgh, Scotland) 2010;29(1):18-23.
2010: Kirk L English; Douglas Paddon-Jones
Protecting muscle mass and function in older adults during bed rest.
Current opinion in clinical nutrition and metabolic care 2010;13(1):34-9.
2009: T Brock Symons; Melinda Sheffield-Moore; Robert R Wolfe; Douglas Paddon-Jones
A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects.
Journal of the American Dietetic Association 2009;109(9):1582-6.
2009: Lichar Dillon; Melinda Sheffield-Moore; Douglas Paddon-Jones; Charles Gilkison; Arthur P Sanford; Shanon L Casperson; Jie Jiang; David L Chinkes; Randall J Urban
Amino acid supplementation increases lean body mass, basal muscle protein synthesis, and insulin-like growth factor-I expression in older women.
The Journal of clinical endocrinology and metabolism 2009;94(5):1630-7.
2009: Douglas Paddon-Jones; Blake B Rasmussen
Dietary protein recommendations and the prevention of sarcopenia.
Current opinion in clinical nutrition and metabolic care 2009;12(1):86-90.
2008: Patrick Kortebein; T Brock Symons; Arny Ferrando; Douglas Paddon-Jones; Ola Ronsen; Elizabeth Protas; Scott Conger; Juan Lombeida; Robert Wolfe; William J Evans
Functional impact of 10 days of bed rest in healthy older adults.
The journals of gerontology. Series A, Biological sciences and medical sciences 2008;63(10):1076-81.
2008: Douglas Paddon-Jones; Kevin R Short; Wayne W Campbell; Elena Volpi; Robert R Wolfe
Role of dietary protein in the sarcopenia of aging.
The American journal of clinical nutrition 2008;87(5):1562S-1566S.
2008: Douglas Paddon-Jones; Eric C Westman; Richard D Mattes; Robert R Wolfe; Arne Astrup; Margriet Westerterp-Plantenga
Protein, weight management, and satiety.
The American journal of clinical nutrition 2008;87(5):1558S-1561S.
2007: Lichar Dillon; Elena Volpi; Robert R Wolfe; Sandeep Sinha; Arthur P Sanford; Concepcion D Arrastia; Randall J Urban; Shanon L Casperson; Douglas Paddon-Jones; Melinda Sheffield-Moore
Amino acid metabolism and inflammatory burden in ovarian cancer patients undergoing intense oncological therapy.
Clinical nutrition (Edinburgh, Scotland) 2007;26(6):736-43.
2007: Melanie G Cree; Bradley R Newcomer; Laura K Read; Melinda Sheffield-Moore; Douglas Paddon-Jones; David L Chinkes; Asle Aarsland; Robert R Wolfe
Plasma triglycerides are not related to tissue lipids and insulin sensitivity in elderly following PPAR-alpha agonist treatment.
Mechanisms of ageing and development 2007;128(10):558-65.
2007: T Brock Symons; Scott E Schutzler; Tara L Cocke; David L Chinkes; Robert R Wolfe; Douglas Paddon-Jones
Aging does not impair the anabolic response to a protein-rich meal.
The American journal of clinical nutrition 2007;86(2):451-6.
2007: Robert H Fitts; JG Romatowski; J R Peters; Douglas Paddon-Jones; R R Wolfe; Arny Ferrando
The deleterious effects of bed rest on human skeletal muscle fibers are exacerbated by hypercortisolemia and ameliorated by dietary supplementation.
American journal of physiology. Cell physiology 2007;293(1):C313-20.
2007: Peter Uchakin; Raymond P Stowe; Douglas Paddon-Jones; Brian W Tobin; Arny Ferrando; Robert R Wolfe
Cytokine secretion and latent herpes virus reactivation with 28 days of horizontal hypokinesia.
Aviation, space, and environmental medicine 2007;78(6):608-12.
2006: Douglas Paddon-Jones; Melinda Sheffield-Moore; Melanie G Cree; Susan J Hewlings; Asle Aarsland; Robert R Wolfe; Arny Ferrando
Atrophy and impaired muscle protein synthesis during prolonged inactivity and stress.
The Journal of clinical endocrinology and metabolism 2006;91(12):4836-41.
2006: Melinda Sheffield-Moore; Douglas Paddon-Jones; Shanon L Casperson; Charles Gilkison; Elena Volpi; Steven Wolf; Jie Jiang; Judah I Rosenblatt; Randall J Urban
Androgen therapy induces muscle protein anabolism in older women.
The Journal of clinical endocrinology and metabolism 2006;91(10):3844-9.
2006: Douglas Paddon-Jones
Interplay of stress and physical inactivity on muscle loss: Nutritional countermeasures.
The Journal of nutrition 2006;136(8):2123-6.
2006: Arny Ferrando; Douglas Paddon-Jones; Robert R Wolfe
Bed rest and myopathies.
Current opinion in clinical nutrition and metabolic care 2006;9(4):410-5.
2006: Douglas Paddon-Jones; Melinda Sheffield-Moore; Christos S Katsanos; Xiao-Jun Zhang; Robert R Wolfe
Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein.
Experimental gerontology 2006;41(2):215-9.
2005: Douglas Paddon-Jones; A Keech; Andrew Lonergan; Peter J Abernethy
Differential expression of muscle damage in humans following acute fast and slow velocity eccentric exercise.
Journal of science and medicine in sport / Sports Medicine Australia 2005;8(3):255-63.
2005: Douglas Paddon-Jones; Robert R Wolfe; Arny Ferrando
Amino acid supplementation for reversing bed rest and steroid myopathies.
The Journal of nutrition 2005;135(7):1809S-1812S.
2005: Sara R Zwart; Janis E Davis-Street; Douglas Paddon-Jones; Arny Ferrando; R R Wolfe; Scott M Smith
Amino acid supplementation alters bone metabolism during simulated weightlessness.
Journal of applied physiology (Bethesda, Md. : 1985) 2005;99(1):134-40.
2005: Melinda Sheffield-Moore; Douglas Paddon-Jones; Arthur P Sanford; Judah I Rosenblatt; A G Matlock; Melanie G Cree; Robert R Wolfe
Mixed muscle and hepatic derived plasma protein metabolism is differentially regulated in older and younger men following resistance exercise.
American journal of physiology. Endocrinology and metabolism 2005;288(5):E922-9.
2005: Douglas Paddon-Jones; Melinda Sheffield-Moore; Asle Aarsland; Robert R Wolfe; Arny Ferrando
Exogenous amino acids stimulate human muscle anabolism without interfering with the response to mixed meal ingestion.
American journal of physiology. Endocrinology and metabolism 2005;288(4):E761-7.
2005: Douglas Paddon-Jones; Melinda Sheffield-Moore; Randall J Urban; Asle Aarsland; Robert R Wolfe; Arny Ferrando
The catabolic effects of prolonged inactivity and acute hypercortisolemia are offset by dietary supplementation.
The Journal of clinical endocrinology and metabolism 2005;90(3):1453-9.
2004: Douglas Paddon-Jones; Elisabet Børsheim; Robert R Wolfe
Potential ergogenic effects of arginine and creatine supplementation.
The Journal of nutrition 2004;134(10 Suppl):2888S-2894S; discussion 2895S.
2004: Douglas Paddon-Jones; Melinda Sheffield-Moore; Randall J Urban; Arthur P Sanford; Asle Aarsland; Robert R Wolfe; Arny Ferrando
Essential amino acid and carbohydrate supplementation ameliorates muscle protein loss in humans during 28 days bedrest.
The Journal of clinical endocrinology and metabolism 2004;89(9):4351-8.
2004: Melinda Sheffield-Moore; Catherine W Yeckel; Elena Volpi; Steven Wolf; Beatrice Morio; David L Chinkes; Douglas Paddon-Jones; Robert R Wolfe
Postexercise protein metabolism in older and younger men following moderate-intensity aerobic exercise.
American journal of physiology. Endocrinology and metabolism 2004;287(3):E513-22.
2004: Douglas Paddon-Jones; Melinda Sheffield-Moore; Xiao-Jun Zhang; Elena Volpi; Steven Wolf; Asle Aarsland; Arny Ferrando; Robert R Wolfe
Amino acid ingestion improves muscle protein synthesis in the young and elderly.
American journal of physiology. Endocrinology and metabolism 2004;286(3):E321-8.
2003: Douglas Paddon-Jones; Melinda Sheffield-Moore; Daniel L Creson; Arthur P Sanford; Steven Wolf; Robert R Wolfe; Arny Ferrando
Hypercortisolemia alters muscle protein anabolism following ingestion of essential amino acids.
American journal of physiology. Endocrinology and metabolism 2003;284(5):E946-53.
2003: Arny Ferrando; Melinda Sheffield-Moore; Douglas Paddon-Jones; Robert R Wolfe; Randall J Urban
Differential anabolic effects of testosterone and amino acid feeding in older men.
The Journal of clinical endocrinology and metabolism 2003;88(1):358-62.
2002: Blake B Rasmussen; Ulf C Holmbäck; Elena Volpi; Beatrice Morio-Liondore; Douglas Paddon-Jones; Robert R Wolfe
Malonyl coenzyme A and the regulation of functional carnitine palmitoyltransferase-1 activity and fat oxidation in human skeletal muscle.
The Journal of clinical investigation 2002;110(11):1687-93.
2002: Arny Ferrando; Douglas Paddon-Jones; Robert R Wolfe
Alterations in protein metabolism during space flight and inactivity.
Nutrition (Burbank, Los Angeles County, Calif.) 2002;18(10):837-41.
2001: Douglas Paddon-Jones; A Keech; David Jenkins
Short-term beta-hydroxy-beta-methylbutyrate supplementation does not reduce symptoms of eccentric muscle damage.
International journal of sport nutrition and exercise metabolism 2001;11(4):442-50.
2001: Douglas Paddon-Jones; M Leveritt; Andrew Lonergan; Peter J Abernethy
Adaptation to chronic eccentric exercise in humans: the influence of contraction velocity.
European journal of applied physiology 2001;85(5):466-71.
2001: Douglas Paddon-Jones; Peter J Abernethy
Acute adaptation to low volume eccentric exercise.
Medicine and science in sports and exercise 2001;33(7):1213-9.
2000: Douglas Paddon-Jones; M Muthalib; David Jenkins
The effects of a repeated bout of eccentric exercise on indices of muscle damage and delayed onset muscle soreness.
Journal of science and medicine in sport / Sports Medicine Australia 2000;3(1):35-43.
1997: Douglas Paddon-Jones; B M Quigley
Effect of cryotherapy on muscle soreness and strength following eccentric exercise.
International journal of sports medicine 1997;18(8):588-93.