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Hesed Padilla-Nash

Research Profile

Procedures

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Nucleic Acid Hybridization

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Genes, myc

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Chromosomal Instability

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Hesed Padilla-Nash; Rea Ravin; Danny Wangsa; Raluca Yonescu; Linda Barenboim; Kathleen Dorritie; Karen Hathcock; Daniel Hoeppner; Yue Hu; Turid Knutsen; David Mack; Nicole McNeil; Thomas Ried
Spontaneous transformation of murine epithelial cells requires the early acquisition of specific chromosomal aneuploidies and genomic imbalances.
Matthew J Olnes; Hesed Padilla-Nash; Loretta Pfannes; Andrea Poon; Thomas Ried; Susan F Leitman; Kelsey Loeliger; Susan J Miranda; Zachary Tucker; Yu Ying Yau; Neal S Young; Elaine M Sloand
Effects of granulocyte-colony-stimulating factor on Monosomy 7 aneuploidy in healthy hematopoietic stem cell and granulocyte donors.
Turid Knutsen; Hesed Padilla-Nash; Danny Wangsa; Linda Barenboim-Stapleton; Jordi Camps; Nicole McNeil; Michael J Difilippantonio; Thomas Ried
Definitive molecular cytogenetic characterization of 15 colorectal cancer cell lines.

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2012: Hesed Padilla-Nash; Rea Ravin; Danny Wangsa; Raluca Yonescu; Linda Barenboim; Kathleen Dorritie; Karen Hathcock; Daniel Hoeppner; Yue Hu; Turid Knutsen; David Mack; Nicole McNeil; Thomas Ried
Spontaneous transformation of murine epithelial cells requires the early acquisition of specific chromosomal aneuploidies and genomic imbalances.
Genes, chromosomes & cancer 2012;51(4):353-74.
2012: Matthew J Olnes; Hesed Padilla-Nash; Loretta Pfannes; Andrea Poon; Thomas Ried; Susan F Leitman; Kelsey Loeliger; Susan J Miranda; Zachary Tucker; Yu Ying Yau; Neal S Young; Elaine M Sloand
Effects of granulocyte-colony-stimulating factor on Monosomy 7 aneuploidy in healthy hematopoietic stem cell and granulocyte donors.
Transfusion 2012;52(3):537-41.
2010: Turid Knutsen; Hesed Padilla-Nash; Danny Wangsa; Linda Barenboim-Stapleton; Jordi Camps; Nicole McNeil; Michael J Difilippantonio; Thomas Ried
Definitive molecular cytogenetic characterization of 15 colorectal cancer cell lines.
Genes, chromosomes & cancer 2010;49(3):204-23.
2010: Youfeng Yang; Vladimir A Valera; Hesed Padilla-Nash; Carole Sourbier; Cathy D Vocke; Manish Vira; Mones Abu-Asab; Gennady Bratslavsky; Maria Tsokos; Maria J Merino; Peter A Pinto; Ramaprasad Srinivasan; Thomas Ried; Len Neckers; W Marston Linehan
UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer.
Cancer genetics and cytogenetics 2010;196(1):45-55.
2009: Jordi Camps; Quang Tri Nguyen; Hesed Padilla-Nash; Turid Knutsen; Nicole McNeil; Danny Wangsa; Amanda B Hummon; Marian Grade; Thomas Ried; Michael J Difilippantonio
Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancer.
Genes, chromosomes & cancer 2009;48(11):1002-17.
2008: William G Nash; Joan C Menninger; Hesed Padilla-Nash; Gary Stone; Polina L Perelman; Stephen J O'Brien
The ancestral carnivore karyotype (2n = 38) lives today in ringtails.
The Journal of heredity 2008;99(3):241-53.
2008: Eriko Michishita; Ronald A McCord; Elisabeth Berber; Mitomu Kioi; Hesed Padilla-Nash; Mara Damian; Peggie Cheung; Rika Kusumoto; Tiara L A Kawahara; J Carl Barrett; Howard Y Chang; Vilhelm A Bohr; Thomas Ried; Or Gozani; Katrin F Chua
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin.
Nature 2008;452(7186):492-6.
2008: Youfeng Yang; Hesed Padilla-Nash; Manish Vira; Mones S Abu-Asab; Daniel Val; Robert Worrell; Maria Tsokos; Maria J Merino; Christian P Pavlovich; Thomas Ried; W Marston Linehan; Cathy D Vocke
The UOK 257 cell line: a novel model for studies of the human Birt-Hogg-Dubé gene pathway.
Cancer genetics and cytogenetics 2008;180(2):100-9.
2008: Benjamin J Raphael; Stanislav Volik; Peng Yu; Chunxiao Wu; Guiqing Huang; Elena Linardopoulou; Barbara J Trask; Frederic Waldman; Joseph F Costello; Kenneth J Pienta; Gordon B Mills; Krystyna Bajsarowicz; Yasuko Kobayashi; Shivaranjani Sridharan; Pamela L Paris; Quanzhou Tao; Sarah J Aerni; Raymond P Brown; Ali Bashir; Joe Gray; Jan-Fang Cheng; Pieter de Jong; Mikhail Nefedov; Thomas Ried; Hesed Padilla-Nash; Colin C Collins
A sequence-based survey of the complex structural organization of tumor genomes.
Genome biology 2008;9(3):R59.
2007: Ming-Jiu Chen; Lavinia C Dumitrache; Danny Wangsa; Sheng-Mei Ma; Hesed Padilla-Nash; Thomas Ried; Edward Hasty
Cisplatin depletes TREX2 and causes Robertsonian translocations as seen in TREX2 knockout cells.
Cancer research 2007;67(19):9077-83.
2007: Dominik M Duelli; Hesed Padilla-Nash; berman david; KATHLEEN MURPHY; Thomas Ried; Yuri Lazebnik
A virus causes cancer by inducing massive chromosomal instability through cell fusion.
Current biology : CB 2007;17(5):431-7.
2007: Hesed Padilla-Nash; Kaida Wu; Helle Just; Thomas Ried; Kristian Thestrup-Pedersen
Spectral karyotyping demonstrates genetically unstable skin-homing T lymphocytes in cutaneous T-cell lymphoma.
Experimental dermatology 2007;16(2):98-103.
2006: Khalil Helou; Hesed Padilla-Nash; Danny Wangsa; Elin Karlsson; Lovisa Osterberg; Per Karlsson; Thomas Ried; Turid Knutsen
Comparative genome hybridization reveals specific genomic imbalances during the genesis from benign through borderline to malignant ovarian tumors.
Cancer genetics and cytogenetics 2006;170(1):1-8.
2006: Masako Miura; Yasuo Miura; Hesed Padilla-Nash; Alfredo A Molinolo; BAOJIN FU; Vyomesh Patel; Byoung-Moo Seo; Wataru Sonoyama; Jenny J Zheng; Carl C Baker; Wanjun Chen; Thomas Ried; Songtao Shi
Accumulated chromosomal instability in murine bone marrow mesenchymal stem cells leads to malignant transformation.
Stem cells (Dayton, Ohio) 2006;24(4):1095-103.
2006: Hesed Padilla-Nash; Linda Barenboim-Stapleton; Michael J Difilippantonio; Thomas Ried
Spectral karyotyping analysis of human and mouse chromosomes.
Nature protocols 2006;1(6):3129-42.
2005: Kevin G Chen; Yan C Wang; Marci E Schaner; Brian Francisco; George E Durán; Dejan Juric; Lyn M Huff; Hesed Padilla-Nash; Thomas Ried; Tito Fojo; Kevin Gang Chen
Genetic and epigenetic modeling of the origins of multidrug-resistant cells in a human sarcoma cell line.
Cancer research 2005;65(20):9388-97.
2005: Turid Knutsen; Vasuki Gobu; Rodger Knaus; Hesed Padilla-Nash; Meena Augustus; Robert L Strausberg; Ilan R Kirsch; Karl Sirotkin; Thomas Ried
The interactive online SKY/M-FISH & CGH database and the Entrez cancer chromosomes search database: linkage of chromosomal aberrations with the genome sequence.
Genes, chromosomes & cancer 2005;44(1):52-64.
2005: Linda Barenboim-Stapleton; Xuezhong Yang; Maria Tsokos; JON WIGGINTON; Hesed Padilla-Nash; Thomas Ried; Carol Jeanne Thiele
Pediatric pancreatoblastoma: histopathologic and cytogenetic characterization of tumor and derived cell line.
Cancer genetics and cytogenetics 2005;157(2):109-17.
2003: Turid Knutsen; Svetlana Pack; Maria Petropavlovskaja; Hesed Padilla-Nash; Clement Knight; Lyn A Mickley; Thomas Ried; Patrick C Elwood; Susan J Roberts
Cytogenetic, spectral karyotyping, fluorescence in situ hybridization, and comparative genomic hybridization characterization of two new secondary leukemia cell lines with 5q deletions, and MYC and MLL amplification.
Genes, chromosomes & cancer 2003;37(3):270-81.
2003: Christian P Pavlovich; Hesed Padilla-Nash; Danny Wangsa; Michael L Nickerson; Vera Y Matrosova; W Marston Linehan; Thomas Ried; John L Phillips
Patterns of aneuploidy in stage IV clear cell renal cell carcinoma revealed by comparative genomic hybridization and spectral karyotyping.
Genes, chromosomes & cancer 2003;37(3):252-60.
2003: Jeffrey A Toretsky; Eileen M Everly; Hesed Padilla-Nash; Allen R Chen; Lynne V Abruzzo; Allen E Eskenazi; Christopher Frantz; Thomas Ried; Judith Stamberg
Novel translocation in acute megakaryoblastic leukemia (AML-M7).
Journal of pediatric hematology/oncology 2003;25(5):396-402.
2002: Cristina Montagna; Eran R Andrechek; Hesed Padilla-Nash; William J Muller; Thomas Ried
Centrosome abnormalities, recurring deletions of chromosome 4, and genomic amplification of HER2/neu define mouse mammary gland adenocarcinomas induced by mutant HER2/neu.
Oncogene 2002;21(6):890-8.
2002: Eva Hilgenfeld; Cristina Montagna; Hesed Padilla-Nash; Linda Stapleton; Kerstin Heselmeyer-Haddad; Thomas Ried
Spectral karyotyping in cancer cytogenetics.
Methods in molecular medicine 2002;68():29-44.
2001: John L Phillips; S W Hayward; Yunfei Wang; James R Vasselli; Christian P Pavlovich; Hesed Padilla-Nash; J R Pezullo; B Michael Ghadimi; G D Grossfeld; A Rivera; W Marston Linehan; G R Cunha; Thomas Ried
The consequences of chromosomal aneuploidy on gene expression profiles in a cell line model for prostate carcinogenesis.
Cancer research 2001;61(22):8143-9.
2001: Eva Hilgenfeld; Hesed Padilla-Nash; Nicole McNeil; Turid Knutsen; Cristina Montagna; Joëlle Tchinda; Jürgen Horst; W D Ludwig; Hubert Serve; Thomas Büchner; Wolfgang E Berdel; E Schröck; Thomas Ried
Spectral karyotyping and fluorescence in situ hybridization detect novel chromosomal aberrations, a recurring involvement of chromosome 21 and amplification of the MYC oncogene in acute myeloid leukaemia M2.
British journal of haematology 2001;113(2):305-17.
2001: John L Phillips; B Michael Ghadimi; Danny Wangsa; Hesed Padilla-Nash; Robert Worrell; Stephen Hewitt; McClellan Walther; W Marston Linehan; Richard D Klausner; Thomas Ried
Molecular cytogenetic characterization of early and late renal cell carcinomas in von Hippel-Lindau disease.
Genes, chromosomes & cancer 2001;31(1):1-9.
2001: Hesed Padilla-Nash; Kerstin Heselmeyer-Haddad; Danny Wangsa; H Zhang; B Michael Ghadimi; M Macville; Meena Augustus; E Schröck; Eva Hilgenfeld; Thomas Ried
Jumping translocations are common in solid tumor cell lines and result in recurrent fusions of whole chromosome arms.
Genes, chromosomes & cancer 2001;30(4):349-63.
2001: Eva Hilgenfeld; Hesed Padilla-Nash; E Schröck; Thomas Ried; O A Haas; Hubert Serve
Spectral Karyotyping (SKY) of Hematologic Malignancies.
Methods in molecular medicine 2001;55():65-79.
2001: William G Nash; Joan C Menninger; Johannes Wienberg; Hesed Padilla-Nash; Stephen J O'Brien
The pattern of phylogenomic evolution of the Canidae.
Cytogenetics and cell genetics 2001;95(3-4):210-24.
2000: E Schröck; Hesed Padilla-Nash
Spectral karyotyping and multicolor fluorescence in situ hybridization reveal new tumor-specific chromosomal aberrations.
Seminars in hematology 2000;37(4):334-47.
2000: Turid Knutsen; V Koneti Rao; Thomas Ried; Lyn A Mickley; E Schneider; K Miyake; B Michael Ghadimi; Hesed Padilla-Nash; Svetlana Pack; Lee M Greenberger; Kenneth H Cowan; Michael Dean; Tito Fojo; Susan Bates
Amplification of 4q21-q22 and the MXR gene in independently derived mitoxantrone-resistant cell lines.
Genes, chromosomes & cancer 2000;27(1):110-6.
1999: Lynn M Schriml; Hesed Padilla-Nash; A Coleman; P Moen; William G Nash; Joan C Menninger; G Jones; Thomas Ried; M Dean
Tyramide signal amplification (TSA)-FISH applied to mapping PCR-labeled probes less than 1 kb in size.
BioTechniques 1999;27(3):608-13.
1999: Jan C Liang; Yi Ning; RY Wang; Hesed Padilla-Nash; E Schröck; D Soenksen; Lalitha Nagarajan; Thomas Ried
Spectral karyotypic study of the HL-60 cell line: detection of complex rearrangements involving chromosomes 5, 7, and 16 and delineation of critical region of deletion on 5q31.1.
Cancer genetics and cytogenetics 1999;113(2):105-9.
1999: Hesed Padilla-Nash; William G Nash; G M Padilla; KM Roberson; Cary N Robertson; M Macville; E Schröck; Thomas Ried
Molecular cytogenetic analysis of the bladder carcinoma cell line BK-10 by spectral karyotyping.
Genes, chromosomes & cancer 1999;25(1):53-9.
1999: Eva Hilgenfeld; Hesed Padilla-Nash; E Schröck; Thomas Ried
Analysis of B-cell neoplasias by spectral karyotyping (SKY).
Current topics in microbiology and immunology 1999;246():169-74.
1999: M Macville; E Schröck; Hesed Padilla-Nash; C Keck; B Michael Ghadimi; Drazen Zimonjic; N Popescu; Thomas Ried
Comprehensive and definitive molecular cytogenetic characterization of HeLa cells by spectral karyotyping.
Cancer research 1999;59(1):141-50.
1998: KM Roberson; Donna Yancey; Hesed Padilla-Nash; D W Edwards; William G Nash; S Jacobs; G M Padilla; W A Larchian; Cary N Robertson
Isolation and characterization of a novel human bladder cancer cell line: BK10.
In vitro cellular & developmental biology. Animal 1998;34(7):537-44.
1997: E Schröck; T Veldman; Hesed Padilla-Nash; Yi Ning; J Spurbeck; S Jalal; Lisa Shaffer; P Papenhausen; C Kozma; M C Phelan; E Kjeldsen; S A Schonberg; P O'Brien; Leslie G Biesecker; S du Manoir; Thomas Ried
Spectral karyotyping refines cytogenetic diagnostics of constitutional chromosomal abnormalities.
Human genetics 1997;101(3):255-62.
1997: M Macville; T Veldman; Hesed Padilla-Nash; Danny Wangsa; P O'Brien; E Schröck; Thomas Ried
Spectral karyotyping, a 24-colour FISH technique for the identification of chromosomal rearrangements.
Histochemistry and cell biology 1997;108(4-5):299-305.