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Govindarajan Padmanaban

Research Profile

Chemicals & Drugs

Living Beings

Rats

Anatomy

Physiology

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Publications

TOP 3
Palakkod Govindan Vathsala; Pundi N Rangarajan; Debapriya Bhattacharya; Gobardhan Das; Chaitanya Dende; Viswanathan Arun Nagaraj; Govindarajan Padmanaban
Curcumin-arteether combination therapy of Plasmodium berghei-infected mice prevents recrudescence through immunomodulation.
Viswanathan Arun Nagaraj; Rajavel Arumugam; Dasari Prasad; Pundi N Rangarajan; Govindarajan Padmanaban
Protoporphyrinogen IX oxidase from Plasmodium falciparum is anaerobic and is localized to the mitochondrion.
Viswanathan Arun Nagaraj; Dasari Prasad; Rajavel Arumugam; Pundi N Rangarajan; Govindarajan Padmanaban
Characterization of coproporphyrinogen III oxidase in Plasmodium falciparum cytosol.

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All Publications

2012: Palakkod Govindan Vathsala; Pundi N Rangarajan; Debapriya Bhattacharya; Gobardhan Das; Chaitanya Dende; Viswanathan Arun Nagaraj; Govindarajan Padmanaban
Curcumin-arteether combination therapy of Plasmodium berghei-infected mice prevents recrudescence through immunomodulation.
PloS one 2012;7(1):e29442.
2010: Viswanathan Arun Nagaraj; Rajavel Arumugam; Dasari Prasad; Pundi N Rangarajan; Govindarajan Padmanaban
Protoporphyrinogen IX oxidase from Plasmodium falciparum is anaerobic and is localized to the mitochondrion.
Molecular and biochemical parasitology 2010;174(1):44-52.
2010: Viswanathan Arun Nagaraj; Dasari Prasad; Rajavel Arumugam; Pundi N Rangarajan; Govindarajan Padmanaban
Characterization of coproporphyrinogen III oxidase in Plasmodium falciparum cytosol.
Parasitology international 2010;59(2):121-7.
2009: Viswanathan Arun Nagaraj; Dasari Prasad; Pundi N Rangarajan; Govindarajan Padmanaban
Mitochondrial localization of functional ferrochelatase from Plasmodium falciparum.
Molecular and biochemical parasitology 2009;168(1):109-12.
2009: Viswanathan Arun Nagaraj; Rajavel Arumugam; Nagasuma R Chandra; Dasari Prasad; Pundi N Rangarajan; Govindarajan Padmanaban
Localisation of Plasmodium falciparum uroporphyrinogen III decarboxylase of the heme-biosynthetic pathway in the apicoplast and characterisation of its catalytic properties.
International journal for parasitology 2009;39(5):559-68.
2008: Viswanathan Arun Nagaraj; Rajavel Arumugam; Bulusu Gopalakrishnan; Yeleswarapu Sri Jyothsna; Pundi N Rangarajan; Govindarajan Padmanaban
Unique properties of Plasmodium falciparum porphobilinogen deaminase.
The Journal of biological chemistry 2008;283(1):437-44.
2007: Govindarajan Padmanaban; Viswanathan Arun Nagaraj; Pundi N Rangarajan
An alternative model for heme biosynthesis in the malarial parasite.
Trends in biochemical sciences 2007;32(10):443-9.
2006: Nandakumar Dalavaikodihalli; Viswanathan Arun Nagaraj; Palakkod Govindan Vathsala; Pundi N Rangarajan; Govindarajan Padmanaban
Curcumin-artemisinin combination therapy for malaria.
Antimicrobial agents and chemotherapy 2006;50(5):1859-60.
2005: Govindarajan Padmanaban
How I became a biochemist.
IUBMB life 2005;57(3):193-5.
2005: Raju C Reddy; Palakkodu G Vatsala; Venkateshwar Keshamouni; Govindarajan Padmanaban; Pundi N Rangarajan
Curcumin for malaria therapy.
Biochemical and biophysical research communications 2005;326(2):472-4.
2004: Varadharajan Sundaramurthy; B K Chandrashekar Sagar; Pundi N Rangarajan; Govindarajan Padmanaban
Localization of ferrochelatase in Plasmodium falciparum.
The Biochemical journal 2004;384(Pt 2):429-36.
2004: Palakkod Govindan Vathsala; A Pramanik; Shanmugham Dhanasekaran; C Usha Devi; CR Pillai; Sarala K Subbarao; S K Ghosh; S N Tiwari; T S Sathyanarayan; P R Deshpande; G C Mishra; M R Ranjit; Aditya P Dash; Pundi N Rangarajan; Govindarajan Padmanaban
Widespread occurrence of the Plasmodium falciparum chloroquine resistance transporter (Pfcrt) gene haplotype SVMNT in P. falciparum malaria in India.
The American journal of tropical medicine and hygiene 2004;70(3):256-9.
2004: Shanmugham Dhanasekaran; Nagasuma R Chandra; B K Chandrasekhar Sagar; Pundi N Rangarajan; Govindarajan Padmanaban
Delta-aminolevulinic acid dehydratase from Plasmodium falciparum: indigenous versus imported.
The Journal of biological chemistry 2004;279(8):6934-42.
2003: Govindarajan Padmanaban
Drug targets in malaria parasites.
Advances in biochemical engineering/biotechnology 2003;84():123-41.
2002: Varadharajan Sundaramurthy; Shanmugham Dhanasekaran; ZQ Bonday; Pundi N Rangarajan; Govindarajan Padmanaban
Involvement of delta-aminolaevulinate synthase encoded by the parasite gene in de novo haem synthesis by Plasmodium falciparum.
The Biochemical journal 2002;367(Pt 2):321-7.
2002: Kalpana R Samudre; Sendurai Mani; Palakkod Govindan Vathsala; Pundi N Rangarajan; Govindarajan Padmanaban
Phenobarbitone-mediated translocation of the cytosolic proteins interacting with the 5'-proximal region of rat liver CYP2B1/B2 gene into the nucleus.
Biochemical and biophysical research communications 2002;292(2):312-7.
2000: ZQ Bonday; Shanmugham Dhanasekaran; Pundi N Rangarajan; Govindarajan Padmanaban
Import of host delta-aminolevulinate dehydratase into the malarial parasite: identification of a new drug target.
Nature medicine 2000;6(8):898-903.
2000: Sendurai Mani; S Harish; Palakkod Govindan Vathsala; Pundi N Rangarajan; Govindarajan Padmanaban
Receptor-mediated gene delivery approach demonstrates the role of 5'-proximal DNA region in conferring phenobarbitone responsiveness to CYP2B2 gene in rat liver in vivo.
Biochemical and biophysical research communications 2000;268(3):734-9.
2000: Govindarajan Padmanaban; Pundi N Rangarajan
Heme metabolism of Plasmodium is a major antimalarial target.
Biochemical and biophysical research communications 2000;268(3):665-8.
1998: U Mahadevan; Govindarajan Padmanaban
Cloning and expression of an acyl-CoA dehydrogenase from Mycobacterium tuberculosis.
Biochemical and biophysical research communications 1998;244(3):893-7.
1997: ZQ Bonday; S Taketani; P D Gupta; Govindarajan Padmanaban
Heme biosynthesis by the malarial parasite. Import of delta-aminolevulinate dehydrase from the host red cell.
The Journal of biological chemistry 1997;272(35):21839-46.
1997: Pundi N Rangarajan; P G Vatsala; Mundrigri S Ashok; V K Srinivas; Chittoor M Habibullah; Govindarajan Padmanaban
Non-viral ex vivo hepatic gene transfer by in situ lipofection of liver and intraperitoneal transplantation of hepatocytes.
Gene 1997;190(1):217-21.
1997: S Sultana; C S Nirodi; N Ram; L Prabhu; Govindarajan Padmanaban
A 65-kDa protein mediates the positive role of heme in regulating the transcription of CYP2B1/B2 gene in rat liver.
The Journal of biological chemistry 1997;272(14):8895-900.
1996: C S Nirodi; S Sultana; N Ram; L Prabhu; Govindarajan Padmanaban
Involvement of synthesis and phosphorylation of nuclear protein factors that bind to the positive cis-acting element in the transcriptional activation of the CYP2B1/B2 gene by phenobarbitone in vivo.
Archives of biochemistry and biophysics 1996;331(1):79-86.
1995: L Prabhu; P Upadhya; N Ram; C S Nirodi; S Sultana; P G Vatsala; Sendurai Mani; Pundi N Rangarajan; Avadhesha Surolia; Govindarajan Padmanaban
A model for the transcriptional regulation of the CYP2B1/B2 gene in rat liver.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(21):9628-32.
1995: N Ram; M V Rao; L Prabhu; C S Nirodi; S Sultana; P G Vatsala; Govindarajan Padmanaban
Characterization of a negative cis-acting DNA element regulating the transcription of CYP2B1/B2 gene in rat liver.
Archives of biochemistry and biophysics 1995;317(1):39-45.
1993: N Surolia; G Karthikeyan; Govindarajan Padmanaban
Involvement of cytochrome P-450 in conferring chloroquine resistance to the malarial parasite, Plasmodium falciparum.
Biochemical and biophysical research communications 1993;197(2):562-9.
1992: N Surolia; Govindarajan Padmanaban
de novo biosynthesis of heme offers a new chemotherapeutic target in the human malarial parasite.
Biochemical and biophysical research communications 1992;187(2):744-50.
1992: P Upadhya; M V Rao; V Venkateswar; Pundi N Rangarajan; Govindarajan Padmanaban
Identification and functional characterization of a cis-acting positive DNA element regulating CYP 2B1/B2 gene transcription in rat liver.
Nucleic acids research 1992;20(3):557-62.
1991: V Venkateswar; Govindarajan Padmanaban
Involvement of heme in the transcriptional activation of CYPIIB1/B2 gene by phenobarbitone in rat liver--studies with succinylacetone.
Archives of biochemistry and biophysics 1991;290(1):167-72.
1991: N Surolia; Govindarajan Padmanaban
Chloroquine inhibits heme-dependent protein synthesis in Plasmodium falciparum.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(11):4786-90.
1991: J R Murti; PR Adiga; Govindarajan Padmanaban
Estradiol-17 beta induces polyaromatic hydrocarbon-inducible cytochrome P-450 in chicken liver.
Biochemical and biophysical research communications 1991;175(3):928-35.
1990: M V Rao; Pundi N Rangarajan; Govindarajan Padmanaban
Dexamethasone negatively regulates phenobarbitone-activated transcription but synergistically enhances cytoplasmic levels of cytochrome P-450b/e messenger RNA.
The Journal of biological chemistry 1990;265(10):5617-22.
1989: Govindarajan Padmanaban; V Venkateswar; Pundi N Rangarajan
Haem as a multifunctional regulator.
Trends in biochemical sciences 1989;14(12):492-6.
1989: Pundi N Rangarajan; Govindarajan Padmanaban
Regulation of cytochrome P-450b/e gene expression by a heme- and phenobarbitone-modulated transcription factor.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(11):3963-7.
1988: G J Bhat; Govindarajan Padmanaban
Heme is a positive regulator of cytochrome P-450 gene transcription.
Archives of biochemistry and biophysics 1988;264(2):584-90.
1988: R S Seelan; Govindarajan Padmanaban
A processed pseudogene with an intact coding sequence for rat liver cytochrome c oxidase subunit VIc.
Gene 1988;67(1):125-30.
1988: G Jayarama Bhat; Govindarajan Padmanaban
Heme regulates cytochrome P-450 gene transcription elongation.
Biochemical and biophysical research communications 1988;151(2):737-42.
1987: V J Dwarki; V N Francis; G J Bhat; Govindarajan Padmanaban
Regulation of cytochrome P-450 messenger RNA and apoprotein levels by heme.
The Journal of biological chemistry 1987;262(35):16958-62.
1987: G J Bhat; Pundi N Rangarajan; Govindarajan Padmanaban
Differential effects of cycloheximide on rat liver cytochrome P-450 gene transcription in the whole animal and hepatoma cell culture.
Biochemical and biophysical research communications 1987;148(3):1118-23.
1987: Pundi N Rangarajan; H Ravishankar; Govindarajan Padmanaban
Isolation of a cytochrome P-450e gene variant and characterization of its 5' flanking sequences.
Biochemical and biophysical research communications 1987;144(1):258-63.
1986: S Satyabhama; R S Seelan; Govindarajan Padmanaban
Expression of cytochrome P-450 and albumin genes in rat liver: effect of xenobiotics.
Biochemistry 1986;25(16):4508-12.
1986: V N Francis; V I Dwarki; Govindarajan Padmanaban
A comparative study of the regulation of cytochrome P-450 and glutathione transferase gene expression in rat liver.
Nucleic acids research 1986;14(6):2497-510.
1985: H Ravishankar; Govindarajan Padmanaban
Turnover of messenger RNA, apoprotein and haem of cytochrome P-450b + e induced by phenobarbitone in rat liver.
The Biochemical journal 1985;229(1):73-9.
1985: H Ravishankar; Govindarajan Padmanaban
Regulation of cytochrome P-450 gene expression. Studies with a cloned probe.
The Journal of biological chemistry 1985;260(3):1588-92.
1984: S Satyabhama; Govindarajan Padmanaban
Effect of thioacetamide on cytochrome P-450 synthesis in rat liver.
The Biochemical journal 1984;218(2):371-7.
1984: S Parimoo; R S Seelan; Brenda Osborne; G Buso; Govindarajan Padmanaban
Construction of a cDNA clone for a nuclear-coded subunit of cytochrome c oxidase from rat liver.
Biochemical and biophysical research communications 1984;118(3):902-9.
1983: H Ravishankar; Govindarajan Padmanaban
Effect of cobalt chloride and 3-amino-1,2,4-triazole on the induction of cytochrome P-450 synthesis by phenobarbitone in rat liver.
Archives of biochemistry and biophysics 1983;225(1):16-24.
1982: S Parimoo; N Rao; Govindarajan Padmanaban
Cytochrome c oxidase is preferentially synthesized in the rough endoplasmic reticulum--mitochondrion complex in rat liver.
The Biochemical journal 1982;208(2):505-7.
1980: S Parimoo; Govindarajan Padmanaban
Biosynthesis of cytoplasmic subunits of cytochrome C oxidase in rat liver.
Biochemical and biophysical research communications 1980;95(4):1673-9.