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Harald Paganetti

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Clemens Grassberger; Antony J Lomax; Noah Choi; Stephen Dowdell; James Shackleford; Greg Sharp; Henning Willers; Harald Paganetti
Motion interplay as a function of patient parameters and spot size in spot scanning proton therapy for lung cancer.
Chuan Zeng; Jason A Efstathiou; Drosoula Giantsoudi; Saveli Goldberg; Clemens Grassberger; Andrzej Niemierko; Harald Paganetti; Alexei Trofimov
Maximizing the biological effect of proton dose delivered with scanned beams via inhomogeneous daily dose distributions.
Chul Hee Min; Harald Paganetti; Thomas Bortfeld; Georges El Fakhri; Kira Grogg; Mauro Testa; Brian A Winey; Xuping Zhu; Helen A Shih
Clinical application of in-room positron emission tomography for in vivo treatment monitoring in proton radiation therapy.

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2013: Clemens Grassberger; Antony J Lomax; Noah Choi; Stephen Dowdell; James Shackleford; Greg Sharp; Henning Willers; Harald Paganetti
Motion interplay as a function of patient parameters and spot size in spot scanning proton therapy for lung cancer.
International journal of radiation oncology, biology, physics 2013;86(2):380-6.
2013: Chuan Zeng; Jason A Efstathiou; Drosoula Giantsoudi; Saveli Goldberg; Clemens Grassberger; Andrzej Niemierko; Harald Paganetti; Alexei Trofimov
Maximizing the biological effect of proton dose delivered with scanned beams via inhomogeneous daily dose distributions.
Medical physics 2013;40(5):051708.
2013: Chul Hee Min; Harald Paganetti; Thomas Bortfeld; Georges El Fakhri; Kira Grogg; Mauro Testa; Brian A Winey; Xuping Zhu; Helen A Shih
Clinical application of in-room positron emission tomography for in vivo treatment monitoring in proton radiation therapy.
International journal of radiation oncology, biology, physics 2013;86(1):183-9.
2013: Harald Paganetti; Peter van Luijk
Biological considerations when comparing proton therapy with photon therapy.
Seminars in radiation oncology 2013;23(2):77-87.
2012: J Perl; J Schumann; J Shin; Bruce A Faddegon; Harald Paganetti
TOPAS: an innovative proton Monte Carlo platform for research and clinical applications.
Medical physics 2012;39(11):6818-37.
2012: Harald Paganetti
Assessment of the risk for developing a second malignancy from scattered and secondary radiation in radiation therapy.
Health physics 2012;103(5):652-61.
2012: Harald Paganetti; Uwe Schneider; Judith A Adams; Basit S Athar; Maryam Moteabbed; Torunn I Yock
Assessment of radiation-induced second cancer risks in proton therapy and IMRT for organs inside the primary radiation field.
Physics in medicine and biology 2012;57(19):6047-61.
2012: J Shin; Harald Paganetti; J Perl; J Schümann; Bruce A Faddegon
A modular method to handle multiple time-dependent quantities in Monte Carlo simulations.
Physics in medicine and biology 2012;57(11):3295-308.
2012: J Schümann; J Shin; Bruce A Faddegon; Harald Paganetti; J Perl
Efficient voxel navigation for proton therapy dose calculation in TOPAS and Geant4.
Physics in medicine and biology 2012;57(11):3281-93.
2012: Harald Paganetti
Range uncertainties in proton therapy and the role of Monte Carlo simulations.
Physics in medicine and biology 2012;57(11):R99-117.
2012: Stephen J Dowdell; Jacob B Flanz; Hanne M Kooy; Peter Metcalfe; Benjamin Clasie; Nicolas Depauw; Anatoly B Rosenfeld; Harald Paganetti
Monte Carlo study of the potential reduction in out-of-field dose using a patient-specific aperture in pencil beam scanning proton therapy.
Physics in medicine and biology 2012;57(10):2829-42.
2012: Jason A Efstathiou; Hsiao-Ming Lu; Maryam Moteabbed; Andrzej Niemierko; Judith A Adams; Basit S Athar; Justin E Bekelman; Jonathan J Paly; William U Shipley; Anthony L Zietman; Harald Paganetti
Adjuvant radiation therapy for early stage seminoma: proton versus photon planning comparison and modeling of second cancer risk.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2012;103(1):12-7.
2012: Alejandro Carabe; Nicolas Depauw; Maryam Moteabbed; Jan Schuemann; Harald Paganetti
Range uncertainty in proton therapy due to variable biological effectiveness.
Physics in medicine and biology 2012;57(5):1159-72.
2012: Maryam Moteabbed; Wesley E Bolch; Robert Drenkhahn; Amy Geyer; Harald Paganetti
Comparison of whole-body phantom designs to estimate organ equivalent neutron doses for secondary cancer risk assessment in proton therapy.
Physics in medicine and biology 2012;57(2):499-515.
2011: C Grassberger; Harald Paganetti
Elevated LET components in clinical proton beams.
Physics in medicine and biology 2011;56(20):6677-91.
2011: Clemens Grassberger; Antony J Lomax; Alexei Trofimov; Harald Paganetti
Variations in linear energy transfer within clinical proton therapy fields and the potential for biological treatment planning.
International journal of radiation oncology, biology, physics 2011;80(5):1559-66.
2011: Xuping Zhu; Thomas R Bortfeld; Juliane Daartz; Samuel España; Norbert Liebsch; Jinsong Ouyang; Harald Paganetti; Georges El Fakhri
Monitoring proton radiation therapy with in-room PET imaging.
Physics in medicine and biology 2011;56(13):4041-57.
2011: I Rinaldi; A Ferrari; A Mairani; Harald Paganetti; Katia Parodi; P Sala
An integral test of FLUKA nuclear models with 160 MeV proton beams in multi-layer Faraday cups.
Physics in medicine and biology 2011;56(13):4001-11.
2011: Samuel España; Harald Paganetti
Uncertainties in planned dose due to the limited voxel size of the planning CT when treating lung tumors with proton therapy.
Physics in medicine and biology 2011;56(13):3843-56.
2011: A Carabe-Fernandez; R G Dale; Harald Paganetti
Repair kinetic considerations in particle beam radiotherapy.
The British journal of radiology 2011;84(1002):546-55.
2011: S España; X Zhu; J Daartz; Georges El Fakhri; Thomas Bortfeld; Harald Paganetti
The reliability of proton-nuclear interaction cross-section data to predict proton-induced PET images in proton therapy.
Physics in medicine and biology 2011;56(9):2687-98.
2011: M Moteabbed; S España; Harald Paganetti
Monte Carlo patient study on the comparison of prompt gamma and PET imaging for range verification in proton therapy.
Physics in medicine and biology 2011;56(4):1063-82.
2011: Basit S Athar; Harald Paganetti
Comparison of second cancer risk due to out-of-field doses from 6-MV IMRT and proton therapy based on 6 pediatric patient treatment plans.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011;98(1):87-92.
2011: Antje-Christin Knopf; Katia Parodi; Harald Paganetti; Thomas Bortfeld; Juliane Daartz; Martijn Engelsman; Norbert J Liebsch; Helen Shih
Accuracy of proton beam range verification using post-treatment positron emission tomography/computed tomography as function of treatment site.
International journal of radiation oncology, biology, physics 2011;79(1):297-304.
2010: Bryan Bednarz; Juliane Daartz; Harald Paganetti
Dosimetric accuracy of planning and delivering small proton therapy fields.
Physics in medicine and biology 2010;55(24):7425-38.
2010: Samuel España; Harald Paganetti
The impact of uncertainties in the CT conversion algorithm when predicting proton beam ranges in patients from dose and PET-activity distributions.
Physics in medicine and biology 2010;55(24):7557-71.
2010: Basit S Athar; Bryan Bednarz; Joao Seco; Cindy Hancox; Harald Paganetti
Comparison of out-of-field photon doses in 6 MV IMRT and neutron doses in proton therapy for adult and pediatric patients.
Physics in medicine and biology 2010;55(10):2879-91.
2010: Harald Paganetti; Michael Goitein; Katia Parodi
Spread-out antiproton beams deliver poor physical dose distributions for radiation therapy.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2010;95(1):79-86.
2010: Ross McGurk; Joao Seco; Marco Riboldi; John A Wolfgang; Paul Segars; Harald Paganetti
Extension of the NCAT phantom for the investigation of intra-fraction respiratory motion in IMRT using 4D Monte Carlo.
Physics in medicine and biology 2010;55(5):1475-90.
2010: Harald Paganetti; Hanne Kooy
Proton radiation in the management of localized cancer.
Expert review of medical devices 2010;7(2):275-85.
2010: X George Xu; Harald Paganetti
Better radiation weighting factors for neutrons generated from proton treatment are needed.
Radiation protection dosimetry 2010;138(4):291-4.
2010: Ben Clasie; Andrew Wroe; Hanne M Kooy; Nicolas Depauw; Jacob B Flanz; Harald Paganetti; Anatoly Rosenfeld
Assessment of out-of-field absorbed dose and equivalent dose in proton fields.
Medical physics 2010;37(1):311-21.
2009: Harald Paganetti; Basit S Athar; Bryan Bednarz
Dose-rate effects when estimating risks for second malignancies: in regard to Fontenot et al (Int J Radiat Oncol Biol Phys 2009;74:616-622).
International journal of radiation oncology, biology, physics 2009;75(5):1624; author reply 1624-5.
2009: Basit S Athar; Harald Paganetti
Neutron equivalent doses and associated lifetime cancer incidence risks for head & neck and spinal proton therapy.
Physics in medicine and biology 2009;54(16):4907-26.
2009: Harald Paganetti
Dose to water versus dose to medium in proton beam therapy.
Physics in medicine and biology 2009;54(14):4399-421.
2009: J Daartz; Martijn Engelsman; Harald Paganetti; M R Bussière
Field size dependence of the output factor in passively scattered proton therapy: influence of range, modulation, air gap, and machine settings.
Medical physics 2009;36(7):3205-10.
2008: Harald Paganetti; Hongyu Jiang; Katia Parodi; Roelf L Slopsema; Martijn Engelsman
Clinical implementation of full Monte Carlo dose calculation in proton beam therapy.
Physics in medicine and biology 2008;53(17):4825-53.
2008: Christina Zacharatou Jarlskog; Harald Paganetti
Sensitivity of different dose scoring methods on organ-specific neutron dose calculations in proton therapy.
Physics in medicine and biology 2008;53(17):4523-32.
2008: Christina Zacharatou Jarlskog; Harald Paganetti
Risk of developing second cancer from neutron dose in proton therapy as function of field characteristics, organ, and patient age.
International journal of radiation oncology, biology, physics 2008;72(1):228-35.
2008: X George Xu; Bryan Bednarz; Harald Paganetti
A review of dosimetry studies on external-beam radiation treatment with respect to second cancer induction.
Physics in medicine and biology 2008;53(13):R193-241.
2008: Christina Zacharatou Jarlskog; Choonik Lee; Wesley E Bolch; X George Xu; Harald Paganetti
Assessment of organ-specific neutron equivalent doses in proton therapy using computational whole-body age-dependent voxel phantoms.
Physics in medicine and biology 2008;53(3):693-717.
2008: Herman D Suit; Hanne M Kooy; Alexei Trofimov; Jonathan Farr; John E Munzenrider; Thomas F DeLaney; Jay Loeffler; Benjamin Clasie; Sairos Safai; Harald Paganetti
Should positive phase III clinical trial data be required before proton beam therapy is more widely adopted? No.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2008;86(2):148-53.
2008: Joao Seco; Gregory C Sharp; Ziji Wu; David Gierga; Florian Buettner; Harald Paganetti
Dosimetric impact of motion in free-breathing and gated lung radiotherapy: a 4D Monte Carlo study of intrafraction and interfraction effects.
Medical physics 2008;35(1):356-66.
2007: Harald Paganetti
The impact of protons on the incidence of second malignancies in radiotherapy by Eric J. Hall; Supp.31-34 2007.
Technology in cancer research & treatment 2007;6(6):661-2.
2007: Katia Parodi; Harald Paganetti; Helen A Shih; Susan Michaud; Jay S Loeffler; Thomas F DeLaney; Norbert J Liebsch; John E Munzenrider; Alan J Fischman; Antje Knopf; Thomas Bortfeld
Patient study of in vivo verification of beam delivery and range, using positron emission tomography and computed tomography imaging after proton therapy.
International journal of radiation oncology, biology, physics 2007;68(3):920-34.
2007: Katia Parodi; Alfredo Ferrari; Florian Sommerer; Harald Paganetti
Clinical CT-based calculations of dose and positron emitter distributions in proton therapy using the FLUKA Monte Carlo code.
Physics in medicine and biology 2007;52(12):3369-87.
2007: Hongyu Jiang; Joao Seco; Harald Paganetti
Effects of Hounsfield number conversion on CT based proton Monte Carlo dose calculations.
Medical physics 2007;34(4):1439-49.
2007: Joao Seco; Gregory C Sharp; J Turcotte; David P Gierga; Thomas Bortfeld; Harald Paganetti
Effects of organ motion on IMRT treatments with segments of few monitor units.
Medical physics 2007;34(3):923-34.
2007: Katia Parodi; Harald Paganetti; Ethan Cascio; Jacob B Flanz; Ali A Bonab; Nathaniel M Alpert; Kevin Lohmann; Thomas Bortfeld
PET/CT imaging for treatment verification after proton therapy: a study with plastic phantoms and metallic implants.
Medical physics 2007;34(2):419-35.
2007: Herman D Suit; Saveli Goldberg; Andrzej Niemierko; Marek Ancukiewicz; Eric Hall; Michael Goitein; Winifred Wong; Harald Paganetti
Secondary carcinogenesis in patients treated with radiation: a review of data on radiation-induced cancers in human, non-human primate, canine and rodent subjects.
Radiation research 2007;167(1):12-42.
2006: Harald Paganetti; Thomas Bortfeld; Thomas F Delaney
Neutron dose in proton radiation therapy: in regard to Eric J. Hall (Int J Radiat Oncol Biol Phys 2006;65:1-7).
International journal of radiation oncology, biology, physics 2006;66(5):1594-5; author reply 1595.
2006: Thomas Bortfeld; Harald Paganetti
The biologic relevance of daily dose variations in adaptive treatment planning.
International journal of radiation oncology, biology, physics 2006;65(3):899-906.
2006: Harald Paganetti
Monte Carlo calculations for absolute dosimetry to determine machine outputs for proton therapy fields.
Physics in medicine and biology 2006;51(11):2801-12.
2005: Hanne M Kooy; Stanley Rosenthal; Martijn Engelsman; Alejandro Mazal; Roelf L Slopsema; Harald Paganetti; Jacob B Flanz
The prediction of output factors for spread-out proton Bragg peak fields in clinical practice.
Physics in medicine and biology 2005;50(24):5847-56.
2005: Harald Paganetti
Changes in tumor cell response due to prolonged dose delivery times in fractionated radiation therapy.
International journal of radiation oncology, biology, physics 2005;63(3):892-900.
2005: Hongyu Jiang; Brian Wang; X George Xu; Herman D Suit; Harald Paganetti
Simulation of organ-specific patient effective dose due to secondary neutrons in proton radiation treatment.
Physics in medicine and biology 2005;50(18):4337-53.
2005: Harald Paganetti
Interpretation of proton relative biological effectiveness using lesion induction, lesion repair, and cellular dose distribution.
Medical physics 2005;32(8):2548-56.
2005: Harald Paganetti; Hongyu Jiang; Alexei Trofimov
4D Monte Carlo simulation of proton beam scanning: modelling of variations in time and space to study the interplay between scanning pattern and time-dependent patient geometry.
Physics in medicine and biology 2005;50(5):983-90.
2004: Harald Paganetti; Hongyu Jiang; Judith A Adams; George T Y Chen; Eike Rietzel
Monte Carlo simulations with time-dependent geometries to investigate effects of organ motion with high temporal resolution.
International journal of radiation oncology, biology, physics 2004;60(3):942-50.
2004: Hongyu Jiang; Harald Paganetti
Adaptation of GEANT4 to Monte Carlo dose calculations based on CT data.
Medical physics 2004;31(10):2811-8.
2004: Harald Paganetti; Hongyu Jiang; S Y Lee; Hanne M Kooy
Accurate Monte Carlo simulations for nozzle design, commissioning and quality assurance for a proton radiation therapy facility.
Medical physics 2004;31(7):2107-18.
2004: Harald Paganetti
Four-dimensional Monte Carlo simulation of time-dependent geometries.
Physics in medicine and biology 2004;49(6):N75-81.
2003: Jacob B Flanz; Harald Paganetti
Monte Carlo calculations in support of the commissioning of the Northeast Proton Therapy Center.
Australasian physical & engineering sciences in medicine / supported by the Australasian College of Physical Scientists in Medicine and the Australasian Association of Physical Sciences in Medicine 2003;26(4):156-61.
2003: Harald Paganetti
Significance and implementation of RBE variations in proton beam therapy.
Technology in cancer research & treatment 2003;2(5):413-26.
2003: Harald Paganetti
Foreword: Hadron therapy--from yesterday's physics laboratory to today's modern clinical routine.
Technology in cancer research & treatment 2003;2(5):353-4.
2003: Harald Paganetti; B Gottschalk
Test of GEANT3 and GEANT4 nuclear models for 160 MeV protons stopping in CH2.
Medical physics 2003;30(7):1926-31.
2003: Herman D Suit; Saveli Goldberg; Andrzej Niemierko; Alexei Trofimov; Judith Adams; Harald Paganetti; George T Y Chen; Thomas Bortfeld; Stanley Rosenthal; Jay Loeffler; Thomas F DeLaney
Proton beams to replace photon beams in radical dose treatments.
Acta oncologica (Stockholm, Sweden) 2003;42(8):800-8.
2002: Harald Paganetti; Andrzej Niemierko; Marek Ancukiewicz; Leo E Gerweck; Michael Goitein; Jay S Loeffler; Herman D Suit
Relative biological effectiveness (RBE) values for proton beam therapy.
International journal of radiation oncology, biology, physics 2002;53(2):407-21.
2002: Harald Paganetti
Nuclear interactions in proton therapy: dose and relative biological effect distributions originating from primary and secondary particles.
Physics in medicine and biology 2002;47(5):747-64.
2001: Harald Paganetti; Michael Goitein
Biophysical modelling of proton radiation effects based on amorphous track models.
International journal of radiation biology 2001;77(9):911-28.
2000: Harald Paganetti; Leo E Gerweck; Michael Goitein
The general relation between tissue response to x-radiation (alpha/beta-values) and the relative biological effectiveness (RBE) of protons: prediction by the Katz track-structure model.
International journal of radiation biology 2000;76(7):985-98.
2000: Harald Paganetti; Michael Goitein
Radiobiological significance of beamline dependent proton energy distributions in a spread-out Bragg peak.
Medical physics 2000;27(5):1119-26.
1999: B Gottschalk; R Platais; Harald Paganetti
Nuclear interactions of 160 MeV protons stopping in copper: a test of Monte Carlo nuclear models.
Medical physics 1999;26(12):2597-601.