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Axel Pähler

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TOP 3
Katja Heinig; Tomohiro Ishikawa; Olaf Kuhlmann; Axel Pähler; Joseph Tardio; Franz Bucheli; Günter Gross; Manfred Zell; Elke Zwanziger; Tomoko Yamashita
Determination of dalcetrapib by liquid chromatography-tandem mass spectrometry.
Thierry Lavé; Herbert Birnböck; Andreas Götschi; Thomas Ramp; Axel Pähler
In vivo and in vitro characterization of ethyl methanesulfonate pharmacokinetics in animals and in human.
Manuel Tzouros; Axel Pähler
A targeted proteomics approach to the identification of peptides modified by reactive metabolites.

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2012: Katja Heinig; Tomohiro Ishikawa; Olaf Kuhlmann; Axel Pähler; Joseph Tardio; Franz Bucheli; Günter Gross; Manfred Zell; Elke Zwanziger; Tomoko Yamashita
Determination of dalcetrapib by liquid chromatography-tandem mass spectrometry.
Journal of pharmaceutical and biomedical analysis 2012;66():314-24.
2009: Thierry Lavé; Herbert Birnböck; Andreas Götschi; Thomas Ramp; Axel Pähler
In vivo and in vitro characterization of ethyl methanesulfonate pharmacokinetics in animals and in human.
Toxicology letters 2009;190(3):303-9.
2009: Manuel Tzouros; Axel Pähler
A targeted proteomics approach to the identification of peptides modified by reactive metabolites.
Chemical research in toxicology 2009;22(5):853-62.
2008: Wolfgang Muster; Alexander Breidenbach; Holger Fischer; Stephan Kirchner; Lutz Müller; Axel Pähler
Computational toxicology in drug development.
Drug discovery today 2008;13(7-8):303-10.
2008: Tina Sicilia; Angela Mally; Ute M D Schauer; Axel Pähler; Wolfgang Völkel
LC-MS/MS methods for the detection of isoprostanes (iPF2alpha-III and 8,12-iso-iPF2alpha-VI) as biomarkers of CCl4-induced oxidative damage to hepatic tissue.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;861(1):48-55.
2006: Rubén Alvarez-Sanchez; François Montavon; Thomas Hartung; Axel Pähler
Thiazolidinedione bioactivation: a comparison of the bioactivation potentials of troglitazone, rosiglitazone, and pioglitazone using stable isotope-labeled analogues and liquid chromatography tandem mass spectrometry.
Chemical research in toxicology 2006;19(8):1106-16.
2006: Wolfgang Völkel; Tina Sicilia; Axel Pähler; W Gsell; Thomas Tatschner; Kurt A Jellinger; Friedrich Leblhuber; Peter Riederer; Werner K Lutz; Mario E Götz
Increased brain levels of 4-hydroxy-2-nonenal glutathione conjugates in severe Alzheimer's disease.
Neurochemistry international 2006;48(8):679-86.
2005: Karoline Scholz; Wolfgang Dekant; Wolfgang Völkel; Axel Pähler
Rapid detection and identification of N-acetyl-L-cysteine thioethers using constant neutral loss and theoretical multiple reaction monitoring combined with enhanced product-ion scans on a linear ion trap mass spectrometer.
Journal of the American Society for Mass Spectrometry 2005;16(12):1976-84.
2005: Wolfgang Völkel; Rubén Alvarez-Sánchez; Idelette Weick; Angela Mally; Wolfgang Dekant; Axel Pähler
Glutathione conjugates of 4-hydroxy-2(E)-nonenal as biomarkers of hepatic oxidative stress-induced lipid peroxidation in rats.
Free radical biology & medicine 2005;38(11):1526-36.
2001: Ian N H White; Nihal Razvi; Anthony H Gibbs; A M Davies; Maurizio Manno; C Zaccaro; Francesco De Matteis; Axel Pähler; Wolfgang Dekant
Neoantigen formation and clastogenic action of HCFC-123 and perchloroethylene in human MCL-5 cells.
Toxicology letters 2001;124(1-3):129-38.
2001: Herbert Zepnik; Axel Pähler; Ute M D Schauer; Wolfgang Dekant
Ochratoxin A-induced tumor formation: is there a role of reactive ochratoxin A metabolites?
Toxicological sciences : an official journal of the Society of Toxicology 2001;59(1):59-67.
2000: Kai Blumbach; Axel Pähler; H M Deger; Wolfgang Dekant
Biotransformation and male rat-specific renal toxicity of diethyl ethyl- and dimethyl methylphosphonate.
Toxicological sciences : an official journal of the Society of Toxicology 2000;53(1):24-32.
1999: Wolfgang Völkel; Axel Pähler; Wolfgang Dekant
Gas chromatography-negative ion chemical ionization mass spectrometry as a powerful tool for the detection of mercapturic acids and DNA and protein adducts as biomarkers of exposure to halogenated olefins.
Journal of chromatography. A 1999;847(1-2):35-46.
1999: Axel Pähler; Wolfgang Völkel; Wolfgang Dekant
Quantitation of N epsilon-(dichloroacetyl)-L-lysine in proteins after perchloroethene exposure by gas chromatography-mass spectrometry using chemical ionization and negative ion detection followingimmunoaffinity chromatography.
Journal of chromatography. A 1999;847(1-2):25-34.
1999: Axel Pähler; Jean C Parker; Wolfgang Dekant
Dose-dependent protein adduct formation in kidney, liver, and blood of rats and in human blood after perchloroethene inhalation.
Toxicological sciences : an official journal of the Society of Toxicology 1999;48(1):5-13.
1999: Axel Pähler; Kai Blumbach; J Herbst; Wolfgang Dekant
Quantitation of alpha2u-globulin in rat kidney cytosol by capillary electrophoresis.
Analytical biochemistry 1999;267(1):203-11.
1998: Wolfgang Völkel; M Friedewald; E Lederer; Axel Pähler; Jean C Parker; Wolfgang Dekant
Biotransformation of perchloroethene: dose-dependent excretion of trichloroacetic acid, dichloroacetic acid, and N-acetyl-S-(trichlorovinyl)-L-cysteine in rats and humans after inhalation.
Toxicology and applied pharmacology 1998;153(1):20-7.
1998: Axel Pähler; G Birner; Jean C Parker; Wolfgang Dekant
Generation of antibodies to Di- and trichloroacetylated proteins and immunochemical detection of protein adducts in rats treated with perchloroethene.
Chemical research in toxicology 1998;11(9):995-1004.
1997: Axel Pähler; G Birner; M Michaela Ott; Wolfgang Dekant
Binding of hexachlorobutadiene to alpha 2u-globulin and its role in nephrotoxicity in rats.
Toxicology and applied pharmacology 1997;147(2):372-80.