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Savita Pahwa

Research Profile

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Natasa Strbo; Monica Vaccari; Donald Stablein; Melvin N Doster; Eva Fisher; Genoveffa Franchini; Louis Gonzalez; Michael A Kolber; Savita Pahwa; Eckhard R Podack
Cutting edge: novel vaccination modality provides significant protection against mucosal infection by highly pathogenic simian immunodeficiency virus.
Philip M Grant; Sudheesh Kanthikeel; Lauren Komarow; Michael M Lederman; Savita Pahwa; Richard B Pollard; Aaron Richterman; Janet Andersen; David M Asmuth; Sridevi Devaraj; Andrew R Zolopa; Irini Sereti
Elevated interleukin 8 and T-helper 1 and T-helper 17 cytokine levels prior to antiretroviral therapy in participants who developed immune reconstitution inflammatory syndrome during ACTG A5164.
Suresh Pallikkuth; Anita Parmigiani; Sandra Y Silva; Margaret A Fischl; Varghese K George; Rajendra Pahwa; Savita Pahwa
Impaired peripheral blood T-follicular helper cell function in HIV-infected nonresponders to the 2009 H1N1/09 vaccine.

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2013: Natasa Strbo; Monica Vaccari; Donald Stablein; Melvin N Doster; Eva Fisher; Genoveffa Franchini; Louis Gonzalez; Michael A Kolber; Savita Pahwa; Eckhard R Podack
Cutting edge: novel vaccination modality provides significant protection against mucosal infection by highly pathogenic simian immunodeficiency virus.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(6):2495-9.
2012: Philip M Grant; Sudheesh Kanthikeel; Lauren Komarow; Michael M Lederman; Savita Pahwa; Richard B Pollard; Aaron Richterman; Janet Andersen; David M Asmuth; Sridevi Devaraj; Andrew R Zolopa; Irini Sereti
Elevated interleukin 8 and T-helper 1 and T-helper 17 cytokine levels prior to antiretroviral therapy in participants who developed immune reconstitution inflammatory syndrome during ACTG A5164.
The Journal of infectious diseases 2012;206(11):1715-23.
2012: Suresh Pallikkuth; Anita Parmigiani; Sandra Y Silva; Margaret A Fischl; Varghese K George; Rajendra Pahwa; Savita Pahwa
Impaired peripheral blood T-follicular helper cell function in HIV-infected nonresponders to the 2009 H1N1/09 vaccine.
Blood 2012;120(5):985-93.
2012: Suresh Pallikkuth; Anita Parmigiani; Savita Pahwa
The role of interleukin-21 in HIV infection.
Cytokine & growth factor reviews 2012;23(4-5):173-80.
2012: Sudheesh Pilakka-Kanthikeel; William Borkowsky; Coleen K Cunningham; Terry Fenton; Sharon Huang; Savita Pahwa
Increased gut microbial translocation in HIV-infected children persists in virologic responders and virologic failures after antiretroviral therapy.
The Pediatric infectious disease journal 2012;31(6):583-91.
2012: Suresh Pallikkuth; Anita Parmigiani; Savita Pahwa
Role of IL-21 and IL-21 receptor on B cells in HIV infection.
Critical reviews in immunology 2012;32(2):173-95.
2011: Suresh Pallikkuth; Sandra Y Silva; Margaret A Fischl; Sudheesh Pilakka Kanthikeel; Rajendra Pahwa; Savita Pahwa
Innate immune defects correlate with failure of antibody responses to H1N1/09 vaccine in HIV-infected patients.
The Journal of allergy and clinical immunology 2011;128(6):1279-85.
2011: Suresh Pallikkuth; Kenneth Rogers; Monica Vaccari; Francios VILLINGER; Melvin Dosterii; Genoveffa Franchini; Rajendra Pahwa; Savita Pahwa
Interleukin-21 administration to rhesus macaques chronically infected with simian immunodeficiency virus increases cytotoxic effector molecules in T cells and NK cells and enhances B cell function without increasing immune activation or viral replication.
Vaccine 2011;29(49):9229-38.
2011: Suresh Pallikkuth; Sudheesh Pilakka Kanthikeel; Sandra Y Silva; Margaret A Fischl; Rajendra Pahwa; Savita Pahwa
Upregulation of IL-21 receptor on B cells and IL-21 secretion distinguishes novel 2009 H1N1 vaccine responders from nonresponders among HIV-infected persons on combination antiretroviral therapy.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(11):6173-81.
2011: Natasa Strbo; Monica Vaccari; Savita Pahwa; Michael A Kolber; Eva Fisher; Louis Gonzalez; Melvin N Doster; Anna Hryniewicz; Barbara K Felber; George N Pavlakis; Genoveffa Franchini; Eckhard R Podack
Gp96 SIV Ig immunization induces potent polyepitope specific, multifunctional memory responses in rectal and vaginal mucosa.
Vaccine 2011;29(14):2619-25.
2011: Anita Parmigiani; Maria F Pallin; Helena Schmidtmayerova; Mathias G Lichtenheld; Savita Pahwa
Interleukin-21 and cellular activation concurrently induce potent cytotoxic function and promote antiviral activity in human CD8 T cells.
Human immunology 2011;72(2):115-23.
2010: Rajendra Pahwa; Shashidhar Jaggaiahgari; Savita Pahwa; Luca Inverardi; Andreas G Tzakis; Camillo Ricordi
Isolation and expansion of human natural T regulatory cells for cellular therapy.
Journal of immunological methods 2010;363(1):67-79.
2010: Adriana Weinberg; Lin-Ye Song; Cindy L Wilkening; Terry Fenton; John Hural; Raul Louzao; Guido Ferrari; Paige E Etter; Mark Berrong; Jennifer D Canniff; Donald Carter; Olivier D Defawe; Ambrosia Garcia; Tania L Garrelts; Rebecca Gelman; Linda K Lambrecht; Savita Pahwa; Sudheesh Pilakka-Kanthikeel; David L Shugarts; Nancy B Tustin
Optimization of storage and shipment of cryopreserved peripheral blood mononuclear cells from HIV-infected and uninfected individuals for ELISPOT assays.
Journal of immunological methods 2010;363(1):42-50.
2010: Maristela Miyamoto; Silvana D Pessoa; Erika Ono; Daisy M Machado; Reinaldo Salomão; Regina Célia de Menezes Succi; Savita Pahwa; Maria Isabel De Moraes-Pinto
Low CD4+ T-cell levels and B-cell apoptosis in vertically HIV-exposed noninfected children and adolescents.
Journal of tropical pediatrics 2010;56(6):427-32.
2010: Bernard J C Macatangay; Lu Zheng; Charles Rinaldo; Alan L Landay; Richard B Pollard; Savita Pahwa; Michael M Lederman; R Pat Bucy
Comparison of immunologic assays for detecting immune responses in HIV immunotherapeutic studies: AIDS Clinical Trials Group Trial A5181.
Clinical and vaccine immunology : CVI 2010;17(9):1452-9.
2010: Meenakshi Sachdeva; Margaret A Fischl; Rajendra Pahwa; Naresh Sachdeva; Savita Pahwa
Immune exhaustion occurs concomitantly with immune activation and decrease in regulatory T cells in viremic chronically HIV-1-infected patients.
Journal of acquired immune deficiency syndromes (1999) 2010;54(5):447-54.
2010: K Boyd; David T Dunn; H Castro; Diana M Gibb; Trinh Duong; Jean-Pierre Aboulker; M Bulterys; Mario Cortina Borja; C Gabiano; L Galli; Carlo Giaquinto; D R Harris; M HugheS; R McKinney; L Mofenson; J Moye; M L Newell; Savita Pahwa; P Palumbo; C Rudin; Mike Sharland; W Shearer; B Thompson; Pat A Tookey
Discordance between CD4 cell count and CD4 cell percentage: implications for when to start antiretroviral therapy in HIV-1 infected children.
AIDS (London, England) 2010;24(8):1213-7.
2010: Natasa Strbo; Savita Pahwa; Michael A Kolber; L Gonzalez; E Fisher; Eckhard R Podack
Cell-secreted Gp96-Ig-peptide complexes induce lamina propria and intraepithelial CD8+ cytotoxic T lymphocytes in the intestinal mucosa.
Mucosal immunology 2010;3(2):182-92.
2010: Philip M Grant; Lauren Komarow; Janet Andersen; Irini Sereti; Savita Pahwa; Michael M Lederman; Joseph Eron; Ian Sanne; William Powderly; Evelyn Hogg; Carol Suckow; Andrew R Zolopa
Risk factor analyses for immune reconstitution inflammatory syndrome in a randomized study of early vs. deferred ART during an opportunistic infection.
PloS one 2010;5(7):e11416.
2009: Irini Sereti; Richard M Dunham; John Spritzler; Evgenia Aga; Michael A Proschan; Kathy Medvik; Catherine A Battaglia; Alan L Landay; Savita Pahwa; Margaret A Fischl; David M Asmuth; Allan Tenorio; John D Altman; Lawrence Fox; Susan Moir; Angela Malaspina; Michel MORRE; Renaud Buffet; Guido Silvestri; Michael M Lederman
IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection.
Blood 2009;113(25):6304-14.
2008: Natasa Strbo; Lesley de Armas; Huanliang Liu; Michael A Kolber; Mathias G Lichtenheld; Savita Pahwa
IL-21 augments natural killer effector functions in chronically HIV-infected individuals.
AIDS (London, England) 2008;22(13):1551-60.
2008: Savita Pahwa; Jennifer S Read; Wanrong Yin; Yvonne Matthews; William Shearer; Clemente Diaz; Kenneth C Rich; Hermann Mendez; Bruce Thompson
CD4+/CD8+ T cell ratio for diagnosis of HIV-1 infection in infants: Women and Infants Transmission Study.
Pediatrics 2008;122(2):331-9.
2008: David Boulware; Steven Callens; Savita Pahwa
Pediatric HIV immune reconstitution inflammatory syndrome.
Current opinion in HIV and AIDS 2008;3(4):461-7.
2008: Jing Zhang; Xinsheng Zhang; Jihua Fu; Zhenqiang Bi; Kristopher L Arheart; Luis B Barreiro; Lluis Quintana-Murci; Savita Pahwa; Huanliang Liu
Protective role of DC-SIGN (CD209) neck-region alleles with <5 repeat units in HIV-1 transmission.
The Journal of infectious diseases 2008;198(1):68-71.
2008: Michael A Kolber; María O Saenz; Tom J Tanner; Kristopher L Arheart; Savita Pahwa; Huanliang Liu
Intensification of a suppressive HAART regimen increases CD4 counts and decreases CD8+ T-cell activation.
Clinical immunology (Orlando, Fla.) 2008;126(3):315-21.
2007: William T Shearer; Savita Pahwa; Jennifer S Read; Jian Chen; Sameera R Wijayawardana; Paul Palumbo; Elaine J Abrams; Stephen R Nesheim; Wanrong Yin; Bruce Thompson; Kirk A Easley
CD4/CD8 T-cell ratio predicts HIV infection in infants: the National Heart, Lung, and Blood Institute P2C2 Study.
The Journal of allergy and clinical immunology 2007;120(6):1449-56.
2007: Satoshi Oizumi; Natasa Strbo; Savita Pahwa; Vadim Deyev; Eckhard R Podack
Molecular and cellular requirements for enhanced antigen cross-presentation to CD8 cytotoxic T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(4):2310-7.
2007: Seema Desai; Aida Chaparro; Huanliang Liu; Patrick A J Haslett; Kristopher L Arheart; Gwendolyn B Scott; Rajendra Pahwa; Savita Pahwa
Impaired CCR7 expression on plasmacytoid dendritic cells of HIV-infected children and adolescents with immunologic and virologic failure.
Journal of acquired immune deficiency syndromes (1999) 2007;45(5):501-7.
2007: Savita Pahwa; Petronella Muresan; John W Sleasman; Terence Fenton; Jack Moye; Audra Deveikis; Diane Wara; Russ Van Dyke
Phase I/II trial of intermittent subcutaneous IL-2 administration in pediatric patients with moderate immune suppression: results of Pediatric AIDS Clinical Trials Study 402.
The Journal of allergy and clinical immunology 2007;119(6):1538-41.
2007: Lesley White; Subramaniam Krishnan; Natasa Strbo; Huanliang Liu; Michael A Kolber; Mathias G Lichtenheld; Rajendra Pahwa; Savita Pahwa
Differential effects of IL-21 and IL-15 on perforin expression, lysosomal degranulation, and proliferation in CD8 T cells of patients with human immunodeficiency virus-1 (HIV).
Blood 2007;109(9):3873-80.
2007: Savita Pahwa
Role of common gamma chain utilizing cytokines for immune reconstitution in HIV infection.
Immunologic research 2007;38(1-3):373-86.
2006: Ashish B Madhok; Kaie Ojamaa; Viraga Haridas; Vincent A Parnell; Savita Pahwa; D Chowdhury
Cytokine response in children undergoing surgery for congenital heart disease.
Pediatric cardiology 2006;27(4):408-13.
2006: Seetha M Lakshmi Tamma; Kun Wook Chung; Tejal Patel; Satya Priya Balan; Savita Pahwa
p38 MAPK plays a role in IL-4 synthesis in jacalin plus CD28-stimulated CD4+ T cells--II.
Journal of leukocyte biology 2006;79(6):1339-47.
2006: Seetha M Lakshmi Tamma; Satya Priya Balan; Kun Wook Chung; Savita Pahwa
The lectin jacalin plus costimulation with anti-CD28 antibody induces phosphorylation of p38 MAPK and IL-4 synthesis-I.
Journal of leukocyte biology 2006;79(4):876-80.
2006: James A Ida; Niraj Shrestha; Seema Desai; Savita Pahwa; Willem A Hanekom; Patrick A J Haslett
A whole blood assay to assess peripheral blood dendritic cell function in response to Toll-like receptor stimulation.
Journal of immunological methods 2006;310(1-2):86-99.
2006: Rajendra Pahwa; Thomas W McCloskey; Olga C Aroniadis; Natasa Strbo; Subramaniam Krishnan; Savita Pahwa
CD8+ T cells in HIV disease exhibit cytokine receptor perturbation and poor T cell receptor activation but are responsive to gamma-chain cytokine-driven proliferation.
The Journal of infectious diseases 2006;193(6):879-87.
2006: Vanessa Howard; Jeffrey M Greene; Savita Pahwa; Jerry A Winkelstein; John M Boyle; Mehmet Kocak; Mary Ellen Conley
The health status and quality of life of adults with X-linked agammaglobulinemia.
Clinical immunology (Orlando, Fla.) 2006;118(2-3):201-8.
2006: Yoshihiko Yamamoto; Rajendra Pahwa; Savita Pahwa
S-nitrosoglutathione modulates CXCR4 and ICOS expression.
Cellular & molecular biology letters 2006;11(1):30-6.
2005: Andrea Kovacs; Grace Montepiedra; Vincent Carey; Savita Pahwa; Adriana Weinberg; Lisa M Frenkel; Edmund V Capparelli; Lynne Mofenson; Elizabeth Smith; Kenneth McIntosh; Sandra K Burchett
Immune reconstitution after receipt of highly active antiretroviral therapy in children with advanced or progressive HIV disease and complete or partial viral load response.
The Journal of infectious diseases 2005;192(2):296-302.
2005: Caterina Cancrini; Maria Luisa Romiti; Andrea Finocchi; Silvia Di Cesare; Patrizia Ciaffi; Claudia Capponi; Savita Pahwa; Paolo Rossi
Post-natal ontogenesis of the T-cell receptor CD4 and CD8 Vbeta repertoire and immune function in children with DiGeorge syndrome.
Journal of clinical immunology 2005;25(3):265-74.
2005: Vincent J Carey; Savita Pahwa; Adriana Weinberg
Reliability of CD4 quantitation in human immunodeficiency virus-positive children: implications for definition of immunologic response to highly active antiretroviral therapy.
Clinical and diagnostic laboratory immunology 2005;12(5):640-3.
2005: Ashish B Madhok; A Chandrasekran; Vincent Parnell; Mysore Gandhi; Devyani Chowdhury; Savita Pahwa
Levels of recent thymic emigrant cells decrease in children undergoing partial thymectomy during cardiac surgery.
Clinical and diagnostic laboratory immunology 2005;12(5):563-5.
2005: Sanjit Fernandes; Surendra Chavan; Vivek Chitnis; Nina Kohn; Savita Pahwa
Simplified fluorescent multiplex PCR method for evaluation of the T-cell receptor V beta-chain repertoire.
Clinical and diagnostic laboratory immunology 2005;12(4):477-83.
2004: Thomas W McCloskey; Viraga Haridas; Lucy Pontrelli; Savita Pahwa
Response to superantigen stimulation in peripheral blood mononuclear cells from children perinatally infected with human immunodeficiency virus and receiving highly active antiretroviral therapy.
Clinical and diagnostic laboratory immunology 2004;11(5):957-62.
2004: Adriana Weinberg; Savita Pahwa; Rebecca Oyomopito; Vincent J Carey; Bonnie Zimmer; Lynne Mofenson; Andrea Kovacs; Sandra K Burchett
Antimicrobial-specific cell-mediated immune reconstitution in children with advanced human immunodeficiency virus infection receiving highly active antiretroviral therapy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004;39(1):107-14.
2003: Viraga Haridas; Thomas W McCloskey; Rajendra Pahwa; Savita Pahwa
Discordant expression of perforin and granzyme A in total and HIV-specific CD8 T lymphocytes of HIV infected children and adolescents.
AIDS (London, England) 2003;17(16):2313-22.
2003: John Ioannidis; Despina G Contopoulos-Ioannidis; Philip S Rosenberg; James J Goedert; Anita De Rossi; Teresa Espanol; Lisa Frenkel; Marie-Jeanne Mayaux; Marie-Louise Newell; Savita Pahwa; Christine Rousseau; Gabriella Scarlatti; Shizuko Sei; Luisa Sen; Thomas R O'Brien
Effects of CCR5-delta32 and CCR2-64I alleles on disease progression of perinatally HIV-1-infected children: an international meta-analysis.
AIDS (London, England) 2003;17(11):1631-8.
2003: Savita Pahwa; Vivek Chitnis; Richard M Mitchell; Sanjit Fernandez; Alamelu Chandrasekharan; Craig M Wilson; Steven D Douglas
CD4+ and CD8+ T cell receptor repertoire perturbations with normal levels of T cell receptor excision circles in HIV-infected, therapy-naive adolescents.
AIDS research and human retroviruses 2003;19(6):487-95.
2003: Seetha M Lakshmi Tamma; VS Kalyanaraman; Savita Pahwa; Paul Dominguez; Ron R Modesto
The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells.
Journal of leukocyte biology 2003;73(5):682-8.
2003: Vivek Chitnis; Rajendra Pahwa; Savita Pahwa
Determinants of HIV-specific CD8 T-cell responses in HIV-infected pediatric patients and enhancement of HIV-gag-specific responses with exogenous IL-15.
Clinical immunology (Orlando, Fla.) 2003;107(1):36-45.
2003: Monica Kharbanda; Thomas W McCloskey; Rajendra Pahwa; Mei Sun; Savita Pahwa
Alterations in T-cell receptor Vbeta repertoire of CD4 and CD8 T lymphocytes in human immunodeficiency virus-infected children.
Clinical and diagnostic laboratory immunology 2003;10(1):53-8.
2002: Thomas W McCloskey; Viraga Haridas; Rajendra Pahwa; Savita Pahwa
T cell receptor V beta repertoire of the antigen specific CD8 T lymphocyte subset of HIV infected children.
AIDS (London, England) 2002;16(11):1459-65.
2001: Thomas W McCloskey; Viraga Haridas; Rajendra Pahwa; Savita Pahwa
Human immunodeficiency virus gag and pol-specific CD8 T cells in perinatal HIV infection.
Cytometry 2001;46(5):265-70.
2001: Surendra Chavan; S Kodoth; Rajendra Pahwa; Savita Pahwa
The HIV protease inhibitor Indinavir inhibits cell-cycle progression in vitro in lymphocytes of HIV-infected and uninfected individuals.
Blood 2001;98(2):383-9.
2001: S Kodoth; S Bakshi; P Scimeca; K Black; Savita Pahwa
Possible linkage of amprenavir with intracranial bleeding in an HIV-infected hemophiliac.
AIDS patient care and STDs 2001;15(7):347-52.
2001: Thomas W McCloskey; Nina Kohn; M Lesser; SS Bakshi; Savita Pahwa
Immunophenotypic analysis of HIV-infected children: alterations within the first year of life, changes with disease progression, and longitudinal analyses of lymphocyte subsets.
Cytometry 2001;46(3):157-65.
2001: Surendra Chavan; B Bennuri; Monica Kharbanda; Alamelu Chandrasekaran; S Bakshi; Savita Pahwa
Evaluation of T cell receptor gene rearrangement excision circles after antiretroviral therapy in children infected with human immunodeficiency virus.
The Journal of infectious diseases 2001;183(10):1445-54.
2001: Tim Niehues; Thomas W McCloskey; Jennifer Ndagijimana; Gerd Horneff; Volker Wahn; Savita Pahwa
Apoptosis in T-lymphocyte subsets in human immunodeficiency virus-infected children measured immediately ex vivo and following in vitro activation.
Clinical and diagnostic laboratory immunology 2001;8(1):74-8.
2000: Monica Kharbanda; S Than; Vivek Chitnis; M Sun; Surendra Chavan; SS Bakshi; Savita Pahwa
Patterns of CD8 T cell clonal dominance in response to change in antiretroviral therapy in HIV-infected children.
AIDS (London, England) 2000;14(15):2229-38.
2000: M Tateyama; Naoki Oyaizu; Thomas W McCloskey; S Than; Savita Pahwa
CD4 T lymphocytes are primed to express Fas ligand by CD4 cross-linking and to contribute to CD8 T-cell apoptosis via Fas/FasL death signaling pathway.
Blood 2000;96(1):195-202.
2000: Jennifer S Read; Kenneth C Rich; James Korelitz; Lynne M Mofenson; R Harris; Jack Moye; William A Meyer; Savita Pahwa; James Bethel; Robert P Nugent
Quantification of human immunodeficiency virus type 1 p24 antigen and antibody rivals human immunodeficiency virus type 1 RNA and CD4+ enumeration for prognosis. National Institute of Child Health and Human Development Intravenous Immunoglobulin Clinical Trial Study Group.
The Pediatric infectious disease journal 2000;19(6):544-51.
2000: N Hosaka; Naoki Oyaizu; S Than; Savita Pahwa
Correlation of loss of CD4 T cells with plasma levels of both soluble form Fas (CD95) Fas ligand (FasL) in HIV-infected infants.
Clinical immunology (Orlando, Fla.) 2000;95(1 Pt 1):20-5.
2000: LR Krilov; Thomas W McCloskey; S H Harkness; Lucy Pontrelli; Savita Pahwa
Alterations in apoptosis of cord and adult peripheral blood mononuclear cells induced by in vitro infection with respiratory syncytial virus.
The Journal of infectious diseases 2000;181(1):349-53.
1999: JW Romano; S Tetali; E M Lee; RN Shurtliff; X P Wang; Savita Pahwa; Mark H Kaplan; Christine C Ginocchio
Genotyping of the CCR5 chemokine receptor by isothermal NASBA amplification and differential probe hybridization.
Clinical and diagnostic laboratory immunology 1999;6(6):959-65.
1999: Surendra Chavan; S L Tamma; Mark H Kaplan; M Gersten; Savita Pahwa
Reduction in T cell apoptosis in patients with HIV disease following antiretroviral therapy.
Clinical immunology (Orlando, Fla.) 1999;93(1):24-33.
1999: S Than; J A Tumaliuan; Seetha M Lakshmi Tamma; M Morales; SS Bakshi; Savita Pahwa
Chemokine pattern in relation to disease state in human immunodeficiency virus-infected children.
AIDS research and human retroviruses 1999;15(14):1279-85.
1999: Narendra Chirmule; Andris Avots; S M LakshmiTamma; Savita Pahwa; Edgar Serfling
CD4-mediated signals induce T cell dysfunction in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(2):644-9.
1999: S Than; Monica Kharbanda; Vivek Chitnis; SS Bakshi; Peter K Gregersen; Savita Pahwa
Clonal dominance patterns of CD8 T cells in relation to disease progression in HIV-infected children.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(6):3680-6.
1999: Rebecca A Betensky; T Calvelli; Savita Pahwa
Predictive value of CD19 measurements for bacterial infections in children infected with human immunodeficiency virus.
Clinical and diagnostic laboratory immunology 1999;6(2):247-53.
1999: Paul E Palumbo; Claire Raskino; Susan A Fiscus; Savita Pahwa; T Schutzbank; Stephen A Spector; Carol J Baker; Janet A Englund
Virologic and immunologic response to nucleoside reverse-transcriptase inhibitor therapy among human immunodeficiency virus-infected infants and children.
The Journal of infectious diseases 1999;179(3):576-83.
1999: Jennifer S Read; James Bethel; D Robert Harris; William A Meyer; James Korelitz; Lynne M Mofenson; Jack Moye; Savita Pahwa; Kenneth C Rich; Robert P Nugent
Serum vitamin A concentrations in a North American cohort of human immunodeficiency virus type 1-infected children. National Institute of Child Health and Human Development Intravenous Immunoglobulin Clinical Trial Study Group.
The Pediatric infectious disease journal 1999;18(2):134-42.
1999: Lynne M Mofenson; D Robert Harris; Kenneth C Rich; William A Meyer; Jennifer S Read; Jack Moye; Robert P Nugent; James Korelitz; James Bethel; Savita Pahwa
Serum HIV-1 p24 antibody, HIV-1 RNA copy number and CD4 lymphocyte percentage are independently associated with risk of mortality in HIV-1-infected children. National Institute of Child Health and Human Development Intravenous Immunoglobulin Clinical Trial Study Group.
AIDS (London, England) 1999;13(1):31-9.
1998: Thomas W McCloskey; SS Bakshi; S Than; P Arman; Savita Pahwa
Immunophenotypic analysis of peripheral blood mononuclear cells undergoing in vitro apoptosis after isolation from human immunodeficiency virus-infected children.
Blood 1998;92(11):4230-7.
1998: Thomas W McCloskey; Surendra Chavan; S M Lakshmi Tamma; Savita Pahwa
Comparison of seven quantitative assays to assess lymphocyte cell death during HIV infection: measurement of induced apoptosis in anti-Fas-treated Jurkat cells and spontaneous apoptosis in peripheral blood mononuclear cells from children infected with HIV.
AIDS research and human retroviruses 1998;14(16):1413-22.
1998: N Hosaka; Naoki Oyaizu; Mark H Kaplan; H Yagita; Savita Pahwa
Membrane and soluble forms of Fas (CD95) and Fas ligand in peripheral blood mononuclear cells and in plasma from human immunodeficiency virus-infected persons.
The Journal of infectious diseases 1998;178(4):1030-9.
1998: T Hattori; H Komoda; Savita Pahwa; M Tateyama; X Zhang; Y Xu; S Oguma; H Tamamura; N Fujii; K Fukutake; T Uchiyama
Decline of anti-DP107 antibody associated with clinical progression.
AIDS (London, England) 1998;12(12):1557-9.
1998: Lisa M Frenkel; James I Mullins; Gerald Learn; LA Manns-Arcuino; B L Herring; Marcia L Kalish; R W Steketee; Donald M Thea; Joan Nichols; S L Liu; ABDALLAH HARMACHE; X He; David Muthui; A Madan; L Hood; Ashley T Haase; Mary Zupancic; KA Staskus; Steven Wolinsky; Paul Krogstad; J Zhao; I Chen; R Koup; D Ho; Bette Korber; Raymond Apple; Robert W Coombs; Savita Pahwa; Norbert J Roberts
Genetic evaluation of suspected cases of transient HIV-1 infection of infants.
Science (New York, N.Y.) 1998;280(5366):1073-7.
1998: S Tetali; SS Bakshi; S Than; Savita Pahwa; E Abrams; J Romano; S G Pahwa
Plasma virus load evaluation in relation to disease progression in HIV-infected children.
AIDS research and human retroviruses 1998;14(7):571-7.
1998: Thomas W McCloskey; Naoki Oyaizu; SS Bakshi; R Kowalski; Nina Kohn; Savita Pahwa
CD95 expression and apoptosis during pediatric HIV infection: early upregulation of CD95 expression.
Clinical immunology and immunopathology 1998;87(1):33-41.
1998: Z Zhou; Cedric H L Shackleton; Savita Pahwa; P C White; Phyllis W Speiser
Prominent sex steroid metabolism in human lymphocytes.
Molecular and cellular endocrinology 1998;138(1-2):61-9.
1998: Paul E Palumbo; Claire Raskino; Susan A Fiscus; Savita Pahwa; Mary Glenn Fowler; Stephen A Spector; Janet A Englund; Carol J Baker
Predictive value of quantitative plasma HIV RNA and CD4+ lymphocyte count in HIV-infected infants and children.
JAMA : the journal of the American Medical Association 1998;279(10):756-61.
1998: Savita Pahwa; M Morales
Interleukin-2 therapy in HIV infection.
AIDS patient care and STDs 1998;12(3):187-97.
1998: Kikuya Sugiura; Savita Pahwa; Y Yamamoto; K Borisov; Rajendra Pahwa; R P Nelson; J Ishikawa; T Iguchi; Naoki Oyaizu; R A Good; Susumu Ikehara
Characterization of natural suppressor cells in human bone marrow.
Stem cells (Dayton, Ohio) 1998;16(2):99-106.
1998: SS Bakshi; L Zhang; D Ho; S Than; Savita Pahwa
Distribution of CCR5delta32 in human immunodeficiency virus-infected children and its relationship to disease course.
Clinical and diagnostic laboratory immunology 1998;5(1):38-40.
1997: Seetha M Lakshmi Tamma; Narendra Chirmule; Thomas W McCloskey; Naoki Oyaizu; VS Kalyanaraman; Savita Pahwa
Signals transduced through the CD4 molecule interfere with TCR/CD3-mediated ras activation leading to T cell anergy/apoptosis.
Clinical immunology and immunopathology 1997;85(2):195-201.
1997: Naoki Oyaizu; Nobuhiko Kayagaki; Hideo Yagita; Savita Pahwa; Yoji Ikawa
Requirement of cell-cell contact in the induction of Jurkat T cell apoptosis: the membrane-anchored but not soluble form of FasL can trigger anti-CD3-induced apoptosis in Jurkat T cells.
Biochemical and biophysical research communications 1997;238(2):670-5.
1997: Seetha M Lakshmi Tamma; Narendra Chirmule; H Yagura; Naoki Oyaizu; VS Kalyanaraman; Savita Pahwa
CD4 cross-linking (CD4XL) induces RAS activation and tumor necrosis factor-alpha secretion in CD4+ T cells.
Blood 1997;90(4):1588-93.
1997: S Than; Naoki Oyaizu; S Tetali; J Romano; Mark H Kaplan; Savita Pahwa
Upregulation of human immunodeficiency virus (HIV) replication by CD4 cross-linking in peripheral blood mononuclear cells of HIV-infected adults.
Journal of virology 1997;71(8):6230-2.
1997: F Hashimoto; Naoki Oyaizu; VS Kalyanaraman; Savita Pahwa
Modulation of Bcl-2 protein by CD4 cross-linking: a possible mechanism for lymphocyte apoptosis in human immunodeficiency virus infection and for rescue of apoptosis by interleukin-2.
Blood 1997;90(2):745-53.
1997: Thomas W McCloskey; T Cavaliere; SS Bakshi; R Harper; J Fagin; Nina Kohn; Savita Pahwa
Immunophenotyping of T lymphocytes by three-color flow cytometry in healthy newborns, children, and adults.
Clinical immunology and immunopathology 1997;84(1):46-55.
1997: S S Bakshi; Paula Britto; Edmund V Capparelli; Lynne Mofenson; Mary Glenn Fowler; S Rasheed; D Schoenfeld; B Zimmer; Y Frank; Ram Yogev; E Jimenez; M Salgo; G Boone; Savita Pahwa
Evaluation of pharmacokinetics, safety, tolerance, and activity of combination of zalcitabine and zidovudine in stable, zidovudine-treated pediatric patients with human immunodeficiency virus infection. AIDS Clinical Trials Group Protocol 190 Team.
The Journal of infectious diseases 1997;175(5):1039-50.
1997: Lynne M Mofenson; James Korelitz; William A Meyer; James Bethel; Kenneth C Rich; Savita Pahwa; Jack Moye; Robert P Nugent; J Read
The relationship between serum human immunodeficiency virus type 1 (HIV-1) RNA level, CD4 lymphocyte percent, and long-term mortality risk in HIV-1-infected children. National Institute of Child Health and Human Development Intravenous Immunoglobulin Clinical Trial Study Group.
The Journal of infectious diseases 1997;175(5):1029-38.
1997: M Ott; S Emiliani; Carine Van Lint; Georges Herbein; JL Lovett; Narendra Chirmule; Thomas W McCloskey; Savita Pahwa; Eric Verdin
Immune hyperactivation of HIV-1-infected T cells mediated by Tat and the CD28 pathway.
Science (New York, N.Y.) 1997;275(5305):1481-5.
1997: Naoki Oyaizu; Y Adachi; F Hashimoto; Thomas W McCloskey; N Hosaka; Nobuhiko Kayagaki; H Yagita; Savita Pahwa
Monocytes express Fas ligand upon CD4 cross-linking and induce CD4+ T cells apoptosis: a possible mechanism of bystander cell death in HIV infection.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(5):2456-63.
1997: J A Tumaliuan; J J Stambouly; R J Schiff; Savita Pahwa; SS Bakshi
Pseudomonas pericarditis and tamponade in an infant with human immunodeficency virus infection.
Archives of pediatrics & adolescent medicine 1997;151(2):207-8.
1997: Thomas W McCloskey; M Ott; E Tribble; S A Khan; Saul Teichberg; M O Paul; Savita Pahwa; Eric Verdin; Narendra Chirmule
Dual role of HIV Tat in regulation of apoptosis in T cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(2):1014-9.
1997: M O Paul; G Toedter; D Hofheinz; S Tetali; S Pelton; M Marecki; A Brena; E J Abrams; Sheldon Landesman; Savita Pahwa
Diagnosis of human immunodeficiency virus type 1 infection in infants by immune complex dissociation p24 assay.
Clinical and diagnostic laboratory immunology 1997;4(1):75-8.
1997: S Than; R Hu; Naoki Oyaizu; J Romano; X Wang; S Sheikh; Savita Pahwa
Cytokine pattern in relation to disease progression in human immunodeficiency virus-infected children.
The Journal of infectious diseases 1997;175(1):47-56.
1996: Y Adachi; Naoki Oyaizu; S Than; Thomas W McCloskey; Savita Pahwa
IL-2 rescues in vitro lymphocyte apoptosis in patients with HIV infection: correlation with its ability to block culture-induced down-modulation of Bcl-2.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(9):4184-93.
1996: Elizabeth Secord; SS Bakshi; S Fikrig; Savita Pahwa
Seronegative HIV disease with seroconversion at 15 months in an infant with advanced AIDS.
Pediatric AIDS and HIV infection 1996;7(5):350-1.
1996: V Scarmato; Yitzchak Frank; A Rozenstein; D Lu; R Hyman; S Bakshi; Savita Pahwa; Steven G Pavlakis
Central brain atrophy in childhood AIDS encephalopathy.
AIDS (London, England) 1996;10(11):1227-31.
1996: Seetha M Lakshmi Tamma; Naoki Oyaizu; Thomas W McCloskey; VS Kalyanaraman; Savita Pahwa
HIV-1 gp 120 blocks jacalin-induced proliferative response in CD4+ T cells: jacalin as a useful surrogate marker for qualitative and quantitative deficiency of CD4+ T cells in HIV-1 infection.
Clinical immunology and immunopathology 1996;80(3 Pt 1):290-7.
1996: R Hu; Naoki Oyaizu; S Than; VS Kalyanaraman; X P Wang; Savita Pahwa
HIV-1 gp160 induces transforming growth factor-beta production in human PBMC.
Clinical immunology and immunopathology 1996;80(3 Pt 1):283-9.
1996: S Sheikh; SS Bakshi; Savita Pahwa
Outcome and survival in HIV-infected infants with Pneumocystis carinii pneumonia and respiratory failure.
Pediatric AIDS and HIV infection 1996;7(3):155-63.
1996: Narendra Chirmule; Savita Pahwa
Envelope glycoproteins of human immunodeficiency virus type 1: profound influences on immune functions.
Microbiological reviews 1996;60(2):386-406.
1996: S Tetali; Elaine J Abrams; SS Bakshi; M Paul; Naoki Oyaizu; Savita Pahwa
Virus load as a marker of disease progression in HIV-infected children.
AIDS research and human retroviruses 1996;12(8):669-75.
1996: D Lu; Steven G Pavlakis; Yitzchak Frank; S Bakshi; Savita Pahwa; R J Gould; Cristina P Sison; C Hsu; M Lesser; M Hoberman; T Barnett; R A Hyman
Proton MR spectroscopy of the basal ganglia in healthy children and children with AIDS.
Radiology 1996;199(2):423-8.
1996: Naoki Oyaizu; Thomas W McCloskey; S Than; Savita Pahwa
Inhibition of CD4 cross-linking-induced lymphocytes apoptosis by vesnarinone as a novel immunomodulating agent: vesnarinone inhibits Fas expression and apoptosis by blocking cytokine secretion.
Blood 1996;87(6):2361-8.
1995: Narendra Chirmule; M Lesser; A Gupta; M Ravipati; Nina Kohn; Savita Pahwa
Immunological characteristics of HIV-infected children: relationship to age, CD4 counts, disease progression, and survival.
AIDS research and human retroviruses 1995;11(10):1209-19.
1995: N Oyaizu; Savita Pahwa
Role of apoptosis in HIV disease pathogenesis.
Journal of clinical immunology 1995;15(5):217-31.
1995: Pradip N Akolkar; Beena Gulwani-Akolkar; Narendra Chirmule; Savita Pahwa; VS Kalyanaraman; Robert Pergolizzi; S Macphail; Jack Silver
The HIV glycoprotein gp 160 has superantigen-like properties.
Clinical immunology and immunopathology 1995;76(3 Pt 1):255-65.
1995: X P Wang; Naoki Oyaizu; Savita Pahwa
Correlation of maternal cytophilic human immunodeficiency virus (HIV)-1 V3 loop peptide-specific antibodies in infants with vertical HIV transmission.
Pediatric research 1995;38(3):384-9.
1995: Naoki Oyaizu; S Than; Thomas W McCloskey; Savita Pahwa
Requirement of p56lck in T-cell receptor/CD3-mediated apoptosis and Fas-ligand induction in Jurkat cells.
Biochemical and biophysical research communications 1995;213(3):994-1001.
1995: Narendra Chirmule; H Goonewardena; Savita Pahwa; R Pasieka; VS Kalyanaraman; S Pahwa
HIV-1 envelope glycoproteins induce activation of activated protein-1 in CD4+ T cells.
The Journal of biological chemistry 1995;270(33):19364-9.
1995: SS Bakshi; S Tetali; Elaine J Abrams; M O Paul; Savita Pahwa
Repeatedly positive human immunodeficiency virus type 1 DNA polymerase chain reaction in human immunodeficiency virus-exposed seroreverting infants.
The Pediatric infectious disease journal 1995;14(8):658-62.
1995: Narendra Chirmule; Thomas W McCloskey; R Hu; VS Kalyanaraman; Savita Pahwa
HIV gp120 inhibits T cell activation by interfering with expression of costimulatory molecules CD40 ligand and CD80 (B71).
Journal of immunology (Baltimore, Md. : 1950) 1995;155(2):917-24.
1995: Pradip N Akolkar; Beena Gulwani-Akolkar; Narendra Chirmule; Savita Pahwa; VS Kalyanaraman; Robert Pergolizzi; S Macphail; Jack Silver
V beta-specific activation of T-cells by the HIV glycoprotein gp160.
Annals of the New York Academy of Sciences 1995;756():447-9.
1995: Thomas W McCloskey; Naoki Oyaizu; Mark H Kaplan; Savita Pahwa
Expression of the Fas antigen in patients infected with human immunodeficiency virus.
Cytometry 1995;22(2):111-4.
1995: Pradip N Akolkar; Narendra Chirmule; Beena Gulwani-Akolkar; Savita Pahwa; VS Kalyanaraman; Robert Pergolizzi; S Macphail; Jack Silver
V beta-specific activation of T cells by the HIV glycoprotein gp 160.
Scandinavian journal of immunology 1995;41(5):487-98.
1995: Steven G Pavlakis; D Lu; Yitzchak Frank; S Bakshi; Savita Pahwa; T A Barnett; M E Porricolo; R J Gould; Molly Nozyce; R A Hyman
Magnetic resonance spectroscopy in childhood AIDS encephalopathy.
Pediatric neurology 1995;12(4):277-82.
1995: Narendra Chirmule; S Than; S A Khan; Savita Pahwa
Human immunodeficiency virus Tat induces functional unresponsiveness in T cells.
Journal of virology 1995;69(1):492-8.
1995: Naoki Oyaizu; Thomas W McCloskey; S Than; R Hu; Savita Pahwa
Mechanism of apoptosis in peripheral blood mononuclear cells of HIV-infected patients.
Advances in experimental medicine and biology 1995;374():101-14.
1994: M Gurram; Savita Pahwa; M Frieri
Augmented interleukin-6 secretion in collagen-stimulated peripheral blood mononuclear cells from patients with systemic sclerosis.
Annals of allergy 1994;73(6):493-6.
1994: R Hu; Naoki Oyaizu; VS Kalyanaraman; Savita Pahwa
HIV-1 gp160 as a modifier of Th1 and Th2 cytokine response: gp160 suppresses interferon-gamma and interleukin-2 production concomitantly with enhanced interleukin-4 production in vitro.
Clinical immunology and immunopathology 1994;73(2):245-51.
1994: Naoki Oyaizu; Thomas W McCloskey; S Than; R Hu; VS Kalyanaraman; Savita Pahwa
Cross-linking of CD4 molecules upregulates Fas antigen expression in lymphocytes by inducing interferon-gamma and tumor necrosis factor-alpha secretion.
Blood 1994;84(8):2622-31.
1994: Narendra Chirmule; VS Kalyanaraman; Savita Pahwa
Signals transduced through the CD4 molecule on T lymphocytes activate NF-kappa B.
Biochemical and biophysical research communications 1994;203(1):498-505.
1994: S Than; Naoki Oyaizu; Rajendra Pahwa; VS Kalyanaraman; Savita Pahwa
Effect of human immunodeficiency virus type-1 envelope glycoprotein gp160 on cytokine production from cord-blood T cells.
Blood 1994;84(1):184-8.
1994: Narendra Chirmule; Naoki Oyaizu; William Saxinger; Savita Pahwa
Nef protein of HIV-1 has B-cell stimulatory activity.
AIDS (London, England) 1994;8(6):733-4.
1994: M Gurram; Narendra Chirmule; X P Wang; N Ponugoti; Savita Pahwa
Increased spontaneous secretion of interleukin 6 and tumor necrosis factor alpha by peripheral blood lymphocytes of human immunodeficiency virus-infected children.
The Pediatric infectious disease journal 1994;13(6):496-501.
1994: X P Wang; M Paul; S Tetali; Elaine J Abrams; Mahrukh Bamji; L Gulick; Narendra Chirmule; Naoki Oyaizu; SS Bakshi; Savita Pahwa
Improved specificity of in vitro anti-HIV antibody production: implications for diagnosis and timing of transmission in infants born to HIV-seropositive mothers.
AIDS research and human retroviruses 1994;10(6):691-9.
1994: M O Paul; S Tetali; Savita Pahwa
Effective use of frozen donor peripheral blood mononuclear cells for human immunodeficiency virus type 1 isolation from vertically infected pediatric patients.
Journal of clinical microbiology 1994;32(5):1379-82.
1994: Narendra Chirmule; X P Wang; R Hu; Naoki Oyaizu; C Roifman; Rajendra Pahwa; VS Kalyanaraman; Savita Pahwa
Envelope glycoproteins of HIV-1 interfere with T-cell-dependent B cell differentiation: role of CD4-MHC class II interaction in the effector phase of T cell help.
Cellular immunology 1994;155(1):169-82.
1994: Thomas W McCloskey; Naoki Oyaizu; M Coronesi; Savita Pahwa
Use of a flow cytometric assay to quantitate apoptosis in human lymphocytes.
Clinical immunology and immunopathology 1994;71(1):14-8.
1994: Narendra Chirmule; Savita Pahwa
HIV-TAR homology with human c-fes oncogene.
Life sciences 1994;54(18):PL313-4.
1993: Naoki Oyaizu; Thomas W McCloskey; M Coronesi; Narendra Chirmule; VS Kalyanaraman; Savita Pahwa
Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals.
Blood 1993;82(11):3392-400.
1993: Yitzchak Frank; Savita Pahwa
Serial brainstem auditory evoked responses in infants and children with AIDS.
Clinical EEG (electroencephalography) 1993;24(4):160-5.
1993: H Yagura; Naoki Oyaizu; Savita Pahwa
Tyrosine phosphorylation of guanosine triphosphatase activating protein by activation via surface IgG in human B cells.
Blood 1993;81(6):1535-9.
1993: Narendra Chirmule; VS Kalyanaraman; S Lederman; Naoki Oyaizu; H Yagura; Michael Yellin; Leonard Chess; Savita Pahwa
HIV-gp 160-induced T cell-dependent B cell differentiation. Role of T cell-B cell activation molecule and IL-6.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(6):2478-86.
1993: S Tetali; Naoki Oyaizu; M Paul; Savita Pahwa
Human immunodeficiency virus type 1 RNA detection in peripheral blood mononuclear cells by polymerase chain reaction: enhanced sensitivity after mitogenic stimulation.
AIDS research and human retroviruses 1993;9(1):77-82.
1992: K Sugiura; Naoki Oyaizu; Rajendra Pahwa; VS Kalyanaraman; Savita Pahwa
Effect of human immunodeficiency virus-1 envelope glycoprotein on in vitro hematopoiesis of umbilical cord blood.
Blood 1992;80(6):1463-9.
1992: Naoki Oyaizu; Narendra Chirmule; H Yagura; Rajendra Pahwa; R A Good; Savita Pahwa
Superantigen staphylococcal enterotoxin B-induced T-helper cell activation is independent of CD4 molecules and phosphatidylinositol hydrolysis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):8035-9.
1992: Yitzchak Frank; S M Vishnubhakat; Savita Pahwa
Brainstem auditory evoked responses in infants and children with AIDS.
Pediatric neurology 1992;8(4):262-6.
1992: Naoki Oyaizu; Narendra Chirmule; Savita Pahwa
Role of CD4 molecule in the induction of interleukin 2 and interleukin 2 receptor in class II major histocompatibility complex-restricted antigen-specific T helper clones. T cell receptor/CD3 complex transmits CD4-dependent and CD4-independent signals.
The Journal of clinical investigation 1992;89(6):1807-16.
1992: Narendra Chirmule; Naoki Oyaizu; VS Kalyanaraman; Savita Pahwa
Inhibition of normal B-cell function by human immunodeficiency virus envelope glycoprotein, gp120.
Blood 1992;79(5):1245-54.
1992: Naoki Oyaizu; Narendra Chirmule; Savita Pahwa
Vaccination with gp160 in HIV.
The New England journal of medicine 1992;326(5):347; author reply 348.
1991: Naoki Oyaizu; Narendra Chirmule; Y Ohnishi; VS Kalyanaraman; Savita Pahwa
Human immunodeficiency virus type 1 envelope glycoproteins gp120 and gp160 induce interleukin-6 production in CD4+ T-cell clones.
Journal of virology 1991;65(11):6277-82.
1991: Mark H Kaplan; W W Hall; M Susin; Savita Pahwa; S Z Salahuddin; C Heilman; J Fetten; M Coronesi; B F Farber; S Smith
Syndrome of severe skin disease, eosinophilia, and dermatopathic lymphadenopathy in patients with HTLV-II complicating human immunodeficiency virus infection.
The American journal of medicine 1991;91(3):300-9.
1991: J B Bussel; J N Graziano; R P Kimberly; Savita Pahwa; L M Aledort
Intravenous anti-D treatment of immune thrombocytopenic purpura: analysis of efficacy, toxicity, and mechanism of effect.
Blood 1991;77(9):1884-93.
1991: Narendra Chirmule; N Oyaizu; V S Kalyanaraman; Savita Pahwa
Misinterpretation of results of cytokine bioassays.
Journal of immunological methods 1991;137(1):141-4.
1990: Talal A Chatila; E Castigli; Rajendra Pahwa; Savita Pahwa; Narendra Chirmule; Naoki Oyaizu; R A Good; Raif S Geha
Primary combined immunodeficiency resulting from defective transcription of multiple T-cell lymphokine genes.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):10033-7.
1990: L K Jung; B F Haynes; S Nakamura; Savita Pahwa; Shu Man Fu
Expression of early activation antigen (CD69) during human thymic development.
Clinical and experimental immunology 1990;81(3):466-74.
1990: M E Conley; R H Buckley; R Hong; C Guerra-Hanson; C M Roifman; J A Brochstein; Savita Pahwa; J M Puck
X-linked severe combined immunodeficiency. Diagnosis in males with sporadic severe combined immunodeficiency and clarification of clinical findings.
The Journal of clinical investigation 1990;85(5):1548-54.
1990: Narendra Chirmule; VS Kalyanaraman; H Slade; Naoki Oyaizu; Savita Pahwa
Requirement of the T cell receptor for antigen presentation by T lymphocytes. Effect of envelope glycoproteins of HIV-1 on antigen presentation by T cells.
Clinical and experimental immunology 1990;80(2):161-6.
1990: Naoki Oyaizu; Narendra Chirmule; VS Kalyanaraman; W W Hall; Rajendra Pahwa; M Shuster; Savita Pahwa
Human immunodeficiency virus type 1 envelope glycoprotein gp120 produces immune defects in CD4+ T lymphocytes by inhibiting interleukin 2 mRNA.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(6):2379-83.
1990: Narendra Chirmule; VS Kalyanaraman; William Saxinger; F Wong-Staal; J Ghrayeb; Savita Pahwa
Localization of B-cell stimulatory activity of HIV-1 to the carboxyl terminus of gp41.
AIDS research and human retroviruses 1990;6(3):299-305.
1990: Savita Pahwa
Immune defects in pediatric AIDS, their pathogenesis, and role of immunotherapy.
Critical care medicine 1990;18(2 Suppl):S138-43.
1990: Savita Pahwa; Narendra Chirmule; Naoki Oyaizu
Clinical and immunologic spectrum of HIV infection in infants and children and disease pathogenesis.
Progress in clinical and biological research 1990;325():393-401.
1990: W Lim; N Sadick; A Gupta; Mark H Kaplan; Savita Pahwa
Skin diseases in children with HIV infection and their association with degree of immunosuppression.
International journal of dermatology 1990;29(1):24-30.
1990: Narendra Chirmule; VS Kalyanaraman; Naoki Oyaizu; H B Slade; Savita Pahwa
Inhibition of functional properties of tetanus antigen-specific T-cell clones by envelope glycoprotein GP120 of human immunodeficiency virus.
Blood 1990;75(1):152-9.
1989: R J Biggar; Savita Pahwa; Howard Minkoff; H Mendes; A Willoughby; S Landesman; James J Goedert
Immunosuppression in pregnant women infected with human immunodeficiency virus.
American journal of obstetrics and gynecology 1989;161(5):1239-44.
1989: Savita Pahwa; Narendra Chirmule; C Leombruno; W Lim; R Harper; R Bhalla; Rajendra Pahwa; R P Nelson; R A Good
In vitro synthesis of human immunodeficiency virus-specific antibodies in peripheral blood lymphocytes of infants.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(19):7532-6.
1989: Savita Pahwa
Intravenous immune globulin in patients with acquired immune deficiency syndrome.
The Journal of allergy and clinical immunology 1989;84(4 Pt 2):625-30; discussion 630-1.
1989: Rajendra Pahwa; Talal A Chatila; Savita Pahwa; C Paradise; N K Day; R Geha; Stanley A Schwartz; H Slade; Naoki Oyaizu; R A Good
Recombinant interleukin 2 therapy in severe combined immunodeficiency disease.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(13):5069-73.
1989: H B Slade; R V Pica; Savita Pahwa
Detection of HIV-specific antibodies in infancy by isoelectric focusing and affinity immunoblotting.
The Journal of infectious diseases 1989;160(1):126-30.
1989: Narendra Chirmule; William Saxinger; Savita Pahwa
Influences of related retroviruses on lymphocyte functions.
FEMS microbiology immunology 1989;1(5):271-8.
1989: H B Slade; J H Greenwood; Robert Beekman; J P McCoy; J L Hudson; Savita Pahwa; Stanley A Schwartz
Flow cytometric analysis of lymphocyte subpopulations in infants with congenital heart disease.
Journal of clinical laboratory analysis 1989;3(1):14-20.
1989: Yitzchak Frank; W Lim; E Kahn; P Farmer; M Gorey; Savita Pahwa
Multiple ischemic infarcts in a child with AIDS, varicella zoster infection, and cerebral vasculitis.
Pediatric neurology 1989;5(1):64-7.
1988: Savita Pahwa; K Biron; W Lim; P Swenson; Mark H Kaplan; N Sadick; Rajendra Pahwa
Continuous varicella-zoster infection associated with acyclovir resistance in a child with AIDS.
JAMA : the journal of the American Medical Association 1988;260(19):2879-82.
1988: Paolo Lusso; Phillip D Markham; Erwin Tschachler; F di Marzo Veronese; S Z Salahuddin; Dharam V Ablashi; Savita Pahwa; K Krohn; Robert C Gallo
In vitro cellular tropism of human B-lymphotropic virus (human herpesvirus-6).
The Journal of experimental medicine 1988;167(5):1659-70.
1988: Savita Pahwa
Human immunodeficiency virus infection in children: nature of immunodeficiency, clinical spectrum and management.
The Pediatric infectious disease journal 1988;7(5 Suppl):S61-71.
1988: W Lim; E Kahn; A Gupta; H Slade; J Fagin; Mark H Kaplan; Fredric Daum; Savita Pahwa
Treatment of cytomegalovirus enterocolitis with ganciclovir in an infant with acquired immunodeficiency syndrome.
The Pediatric infectious disease journal 1988;7(5):354-7.
1988: G P Holmes; Jonathan E Kaplan; N M Gantz; A L Komaroff; Lawrence B Schonberger; S E Straus; J F Jones; R E Dubois; Charlotte Cunningham-Rundles; Savita Pahwa
Chronic fatigue syndrome: a working case definition.
Annals of internal medicine 1988;108(3):387-9.
1988: Narendra Chirmule; VS Kalyanaraman; Naoki Oyaizu; Savita Pahwa
Inhibitory influences of envelope glycoproteins of HIV-1 on normal immune responses.
Journal of acquired immune deficiency syndromes 1988;1(5):425-30.
1987: Rajendra Pahwa; R A Good; Savita Pahwa
Prematurity, hypogammaglobulinemia, and neuropathology with human immunodeficiency virus (HIV) infection.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(11):3826-30.
1987: Mark H Kaplan; M Susin; Savita Pahwa; J Fetten; Steven Allen; Stuart M Lichtman; M G Sarngadharan; Robert C Gallo
Neoplastic complications of HTLV-III infection. Lymphomas and solid tumors.
The American journal of medicine 1987;82(3):389-96.
1987: Mark H Kaplan; N Sadick; N S McNutt; M Meltzer; M G Sarngadharan; Savita Pahwa
Dermatologic findings and manifestations of acquired immunodeficiency syndrome (AIDS).
Journal of the American Academy of Dermatology 1987;16(3 Pt 1):485-506.
1987: M E Weinblatt; P G Scimeca; A G James-Herry; Savita Pahwa
Thrombocytopenia in an infant with AIDS.
American journal of diseases of children (1960) 1987;141(1):15.
1986: Savita Pahwa; Rajendra Pahwa; R A Good; Robert C Gallo; William Saxinger
Stimulatory and inhibitory influences of human immunodeficiency virus on normal B lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(23):9124-8.
1986: M E Harper; Mark H Kaplan; L M Marselle; Savita Pahwa; K J Chayt; M G Sarngadharan; F Wong-Staal; Robert C Gallo
Concomitant infection with HTLV-I and HTLV-III in a patient with T8 lymphoproliferative disease.
The New England journal of medicine 1986;315(17):1073-8.
1986: N Sadick; Mark H Kaplan; Savita Pahwa; M G Sarngadharan
Unusual features of scabies complicating human T-lymphotropic virus type III infection.
Journal of the American Academy of Dermatology 1986;15(3):482-6.
1986: R B Bhalla; Savita Pahwa; Morton K Schwartz
Preclinical determination of AIDS disease by a series of tests.
Clinical chemistry 1986;32(7):1426-7.
1986: R Menez-Bautista; S M Fikrig; Savita Pahwa; M G Sarangadharan; Rand Stoneburner
Monozygotic twins discordant for the acquired immunodeficiency syndrome.
American journal of diseases of children (1960) 1986;140(7):678-9.
1986: C Messina; D Kirkpatrick; P A Fitzgerald; Richard J O'Reilly; F P Siegal; Charlotte Cunningham-Rundles; M Blaese; J Oleske; Savita Pahwa; C Lopez
Natural killer cell function and interferon generation in patients with primary immunodeficiencies.
Clinical immunology and immunopathology 1986;39(3):394-404.
1986: Savita Pahwa; Mark H Kaplan; S Fikrig; Rajendra Pahwa; M G Sarngadharan; M Popovic; Robert C Gallo
Spectrum of human T-cell lymphotropic virus type III infection in children. Recognition of symptomatic, asymptomatic, and seronegative patients.
JAMA : the journal of the American Medical Association 1986;255(17):2299-305.
1986: G S Incefy; Savita Pahwa; Rajendra Pahwa; M G Sarngadharan; R Menez; S Fikrig
Low circulating thymulin-like activity in children with AIDS and AIDS-related complex.
AIDS research 1986;2(2):109-16.
1986: Savita Pahwa; S Fikrig; R Menez; Rajendra Pahwa
Pediatric acquired immunodeficiency syndrome: demonstration of B lymphocyte defects in vitro.
Diagnostic immunology 1986;4(1):24-30.
1986: L F Duffy; Fredric Daum; Ellen Kahn; S Teichberg; Rajendra Pahwa; J Fagin; K Kenigsberg; Mark H Kaplan; S E Fisher; Savita Pahwa
Hepatitis in children with acquired immune deficiency syndrome. Histopathologic and immunocytologic features.
Gastroenterology 1986;90(1):173-81.
1986: Savita Pahwa
Children with AIDS.
Vox sanguinis 1986;51 Suppl 2():33-8.
1986: J Bussel; Savita Pahwa; A Porges; S Cunningham-Rundles; B Koziner; A Morell; S Barandun
Correlation of in vitro antibody synthesis with the outcome of intravenous gamma-globulin treatment of chronic idiopathic thrombocytopenic purpura.
Journal of clinical immunology 1986;6(1):50-6.
1985: Warren A Andiman; R Eastman; K Martin; B Z Katz; Arye Rubinstein; J Pitt; Savita Pahwa; I G Miller
Opportunistic lymphoproliferations associated with Epstein-Barr viral DNA in infants and children with AIDS.
Lancet 1985;2(8469-70):1390-3.
1985: Savita Pahwa; C Sia; R Harper; Rajendra Pahwa
T lymphocyte subpopulations in high-risk infants: influence of age and blood transfusions.
Pediatrics 1985;76(6):914-7.
1985: Savita Pahwa; Rajendra Pahwa; William Saxinger; Robert C Gallo; R A Good
Influence of the human T-lymphotropic virus/lymphadenopathy-associated virus on functions of human lymphocytes: evidence for immunosuppressive effects and polyclonal B-cell activation by banded viral preparations.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(23):8198-202.
1985: Mark H Kaplan; Savita Pahwa; M Popovic; M G Sarngadharan; Robert C Gallo
A classification of HTLV-III infection based on 75 cases seen in a suburban community.
Cancer research 1985;45(9 Suppl):4655s-4658s.
1985: R B Bhalla; B Safai; Savita Pahwa; Morton K Schwartz
Beta 2-microglobulin as a prognostic marker for development of AIDS.
Clinical chemistry 1985;31(8):1411-2.
1985: Savita Pahwa; C Sia; C Te; R Harper; Rajendra Pahwa
Ethnic heterogeneity in the distribution of the OKT4 antigen on lymphocytes: studies in three black families.
Thymus 1985;7(6):357-66.
1985: Savita Pahwa; S Fikrig; Mark H Kaplan; E Kahn; Rajendra Pahwa
Expressions of HTLV-III infection in a pediatric population.
Advances in experimental medicine and biology 1985;187():45-51.
1984: Savita Pahwa; M T Quilop; M Lange; Rajendra Pahwa; M H Grieco
Defective B-lymphocyte function in homosexual men in relation to the acquired immunodeficiency syndrome.
Annals of internal medicine 1984;101(6):757-63.
1984: V Wahn; R A Good; S Gupta; Savita Pahwa; N K Day
Evidence of persistent IgA/IgG circulating immune complexes associated with activation of the complement system in serum of a patient with common variable immune deficiency: anaphylactic reactions to intravenous gammaglobulin.
Acta pathologica, microbiologica, et immunologica Scandinavica. Supplement 1984;284():49-58.
1984: M Lange; E Buimovici-Klein; H Kornfeld; M T Quilop; Savita Pahwa; M Reddy; P Wong; L Phillips; J Kiyasu; M Moriarty
Prospective observations of viral and immunologic abnormalities in homosexual males.
Annals of the New York Academy of Sciences 1984;437():350-63.
1983: Savita Pahwa; D Kirkpatrick; C Ching; C Lopez; Rajendra Pahwa; E Smithwick; Richard J O'Reilly; C August; P Pasquariello; R A Good
Persistent cytomegalovirus infection: association with profound immunodeficiency and treatment with interferon.
Clinical immunology and immunopathology 1983;28(1):77-89.
1983: C Lopez; D Kirkpatrick; S E Read; P A Fitzgerald; J Pitt; Savita Pahwa; C Y Ching; E M Smithwick
Correlation between low natural killing of fibroblasts infected with herpes simplex virus type 1 and susceptibility to herpesvirus infections.
The Journal of infectious diseases 1983;147(6):1030-5.
1982: D S Banker; Rajendra Pahwa; D R Miller; M W Hilgartner; R A Good; Savita Pahwa
Immunoregulatory properties of childhood leukemias.
Journal of clinical immunology 1982;2(3):230-6.
1982: Savita Pahwa; M K Hoffman; Rajendra Pahwa; R A Good
Polyclonal and antigen-specific B-cell responses in patients with common variable immunodeficiency.
Journal of clinical immunology 1982;2(3):205-13.
1982: H S Flamenbaum; B Safai; F P Siegal; Savita Pahwa
Lichen planus in two immunodeficient hosts.
Journal of the American Academy of Dermatology 1982;6(5):918-20.
1982: Savita Pahwa; Rajendra Pahwa; W Friedrich; Richard J O'Reilly; R A Good
Abnormal humoral immune responses in peripheral blood lymphocyte cultures of bone marrow transplant recipients.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(8):2663-7.
1982: W M Gerba; D R Miller; Savita Pahwa; Charlotte Cunningham-Rundles; S Gupta
Chronic granulomatous disease and selective IgA deficiency.
The American journal of pediatric hematology/oncology 1982;4(2):155-60.
1981: J E Vogel; Savita Pahwa; E M Smithwick; R A Good
The role of an adherent cell in the production of monocyte chemotactic factor.
Immunology letters 1981;3(5):273-6.
1981: Savita Pahwa; Rajendra Pahwa; R A Good
Decreased in vitro humoral immune responses in aged humans.
The Journal of clinical investigation 1981;67(4):1094-102.
1981: Savita Pahwa; R A Good; M K Hoffmann
The role of mitogens and antigens in the generation of antibody-producing human B lymphocytes.
Journal of clinical immunology 1981;1(2):101-5.
1981: Rajendra Pahwa; M J Modak; T McMorrow; Savita Pahwa; Gabriel Fernandes; R A Good
Terminal deoxynucleotidyl transferase (TdT) enzyme in thymus and bone marrow. I. Age-associated decline of TdT in humans and mice.
Cellular immunology 1981;58(1):39-48.
1980: Savita Pahwa; Rajendra Pahwa; G Goldstein; R A Good
Immunoregulatory influence of thymic epithelium and thymopoietin on human B-lymphocyte differentiation.
Cellular immunology 1980;56(1):40-6.
1980: Y Reisner; Savita Pahwa; J W Chiao; N Sharon; R L Evans; R A Good
Separation of antibody helper and antibody suppressor human T cells by using soybean agglutinin.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(11):6778-82.
1980: Savita Pahwa; Rajendra Pahwa; R A Good
Heterogeneity of b lymphocyte differentiation in severe combined immunodeficiency disease.
The Journal of clinical investigation 1980;66(3):543-50.
1980: H E Broxmeyer; Rajendra Pahwa; N Jacobsen; L M Pelus; P Ralph; Paul A Meyers; Savita Pahwa; N Kapoor
Specific inhibitory activity against granulocyte-progenitor cells produced by non-T lymphocytes from patients with neutropenia.
Experimental hematology 1980;8(3):278-97.
1980: O P Mittal; Savita Pahwa
Cytogenetical studies on two terrestrial isopods (Crustacea), Philoscia lodnensis Ramakrishna and Porcellio rathkei Brandt.
Cytobios 1980;29(113):17-24.
1979: Rajendra Pahwa; Savita Pahwa; R A Good
T-lymphocyte differentiation in vitro in severe combined immunodeficiency. Defects of stem cells.
The Journal of clinical investigation 1979;64(6):1632-41.
1979: Savita Pahwa; Rajendra Pahwa; G Incefy; E Reece; E Smithwick; Richard J O'Reilly; R A Good
Failure of immunologic reconstitution in a patient with the DiGeorge syndrome after fetal thymus transplantation.
Clinical immunology and immunopathology 1979;14(1):96-106.
1979: Rajendra Pahwa; S Ikehara; Savita Pahwa; R A Good
Thymic function in man.
Thymus 1979;1(1-2):27-58.
1979: J W Chiao; Savita Pahwa; Z A Arlin; R A Good
Association of helper activity for B-lymphocyte differentiation with lymphocytes having both SRBC and complement receptors in a patient with lymphoproliferative disease.
Clinical immunology and immunopathology 1979;13(2):125-35.
1979: Savita Pahwa; L Shou; Rajendra Pahwa; E Smithwick; R A Good
Influence of human thymocytes on B-lymphocyte differentiation in man.
Cellular immunology 1979;44(2):433-41.
1978: Rajendra Pahwa; Savita Pahwa; R A Good
T-lymphocyte differentiation in severe combined immunodeficiency: defects of the thymus.
Clinical immunology and immunopathology 1978;11(4):437-44.
1978: E M Smithwick; M Finelt; Savita Pahwa; R A Good; C K Naspitz; N F Mendes; S Kopersztyk; T J Spira; A J Nahmias
Cranial synostosis in Job's syndrome.
Lancet 1978;1(8068):826.
1978: Savita Pahwa; E M Smithwick; E R Grimes; Richard J O'Reilly; Rajendra Pahwa; R A Good
Chemotactic defects in severe combined immunodeficiency.
The Journal of pediatrics 1978;92(1):43-50.
1978: W B Boone; Richard J O'Reilly; Savita Pahwa; E Grimes; E M Smithwick; R A Good
Acquired CMV chorioretinitis in severe combined immunodeficiency.
Clinical immunology and immunopathology 1978;9(1):129-33.
1977: Richard J O'Reilly; Bo Dupont; Savita Pahwa; E Grimes; E M Smithwick; Rajendra Pahwa; S Schwartz; J A Hansen; F P Siegal; M Sorell; A Svejgaard; C Jersild; M Thomsen; P Platz; P L'Esperance; R A Good
Reconstitution in severe combined immunodeficiency by transplantation of marrow from an unrelated donor.
The New England journal of medicine 1977;297(24):1311-8.
1977: V Lewis; J J Twomey; G Goldstein; Richard J O'Reilly; E Smithwick; Rajendra Pahwa; Savita Pahwa; R A Good; H Schulte-Wisserman; S Horowitz; R Hong; J Jones; O Sieber; C Kirkpatrick; S Polmar; P Bealmear
Circulating thymic-hormone activity in congenital immunodeficiency.
Lancet 1977;2(8036):471-5.
1977: Rajendra Pahwa; Savita Pahwa; R A Good; G S Incefy; Richard J O'Reilly
Rationale for combined use of fetal liver and thymus for immunological reconstitution in patients with variants of severe combined immunodeficiency.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(7):3002-5.
1977: Savita Pahwa; Rajendra Pahwa; E Grimes; E Smithwick
Cellular and humoral components of monocyte and neutrophil chemotaxis in cord blood.
Pediatric research 1977;11(5):677-80.
1977: G S Incefy; M Dardenne; Savita Pahwa; E Grimes; Rajendra Pahwa; E Smithwick; Richard J O'Reilly; R A Good
Thymic activity in severe combined immunodeficiency diseases.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(3):1250-3.
1977: A J Gorski; Bo Dupont; J A Hansen; B Safai; Savita Pahwa; R A Good
Human immunodeficiency disease: impairment of cellular interactions leading to abnormal mediator production in mixed lymphocyte culture reaction.
Journal of immunology (Baltimore, Md. : 1950) 1977;118(3):858-62.
1976: J W Chiao; J Ascensáo; Savita Pahwa; Rajendra Pahwa; R A Good
An analysis of lymphocytes with both T-cell marker and IgG or complement receptors in patients with X-linked agammaglobulinemia.
Clinical immunology and immunopathology 1976;6(2):141-8.
1976: Richard J O'Reilly; L K Everson; G Emödi; J Hansen; E M Smithwick; E Grimes; Savita Pahwa; Rajendra Pahwa; S Schwartz; D Armstrong; F P Siegal; S Gupta; Bo Dupont; R A Good
Effects of exogenous interferon in cytomegalovirus infections complicating bone marrow transplantation.
Clinical immunology and immunopathology 1976;6(1):51-61.