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Manjunath Pai

Research Profile

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Rhonda Hamilton; Darius Ameri; Xia C Thai; Manjunath P Pai
Oral bioavailability of linezolid before and after Roux-en-Y gastric bypass surgery: is dose modification necessary in obese subjects?
Manjunath P Pai; Barbara Zaffo; Wen Zhen Chen; Huadong Cui; Hassan A N El-Fawal; Adinoyi Garba; Shaker A Mousa
Effects of obesity and sex on antimicrobial pharmacokinetics and acute kidney injury: validation of a preclinical model.
Manjunath P Pai
Drug dosing based on weight and body surface area: mathematical assumptions and limitations in obese adults.

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All Publications

2013: Rhonda Hamilton; Darius Ameri; Xia C Thai; Manjunath P Pai
Oral bioavailability of linezolid before and after Roux-en-Y gastric bypass surgery: is dose modification necessary in obese subjects?
The Journal of antimicrobial chemotherapy 2013;68(3):666-73.
2013: Manjunath P Pai; Barbara Zaffo; Wen Zhen Chen; Huadong Cui; Hassan A N El-Fawal; Adinoyi Garba; Shaker A Mousa
Effects of obesity and sex on antimicrobial pharmacokinetics and acute kidney injury: validation of a preclinical model.
Antimicrobial agents and chemotherapy 2013;57(2):716-22.
2012: Manjunath P Pai
Drug dosing based on weight and body surface area: mathematical assumptions and limitations in obese adults.
Pharmacotherapy 2012;32(9):856-68.
2012: Manjunath P Pai
Comment on: Acute renal insufficiency during telavancin therapy in clinical practice.
The Journal of antimicrobial chemotherapy 2012;67(5):1300-1; author reply 1301-2.
2012: Manjunath P Pai; Anne N Nafziger; Joseph S Bertino
The not so "ideal" body weight-based dosing of Integrilin in obesity.
American heart journal 2012;163(4):e23; author reply e25.
2012: Eun Jung Park; Jialu Zhang; Lei Zhang; VICTOR CRENTSIL; Ting Dong; Chia-Wen Ko; John Lawrence; Manjunath P Pai; Nancy N Xu
The influence of body size descriptors on the estimation of kidney function in normal weight, overweight, obese, and morbidly obese adults.
The Annals of pharmacotherapy 2012;46(3):317-28.
2011: Manjunath P Pai; Thomas P Lodise
Oseltamivir and oseltamivir carboxylate pharmacokinetics in obese adults: dose modification for weight is not necessary.
Antimicrobial agents and chemotherapy 2011;55(12):5640-5.
2011: Jill M Butterfield; George L Drusano; Manjunath P Pai; Nimish Patel; Thomas G Rosano; Thomas P Lodise
Refining vancomycin protein binding estimates: identification of clinical factors that influence protein binding.
Antimicrobial agents and chemotherapy 2011;55(9):4277-82.
2011: Manjunath P Pai; Anne N Nafziger; Joseph S Bertino
Simplified estimation of aminoglycoside pharmacokinetics in underweight and obese adult patients.
Antimicrobial agents and chemotherapy 2011;55(9):4006-11.
2011: Manjunath P Pai; Thomas P Lodise
Steady-state plasma pharmacokinetics of oral voriconazole in obese adults.
Antimicrobial agents and chemotherapy 2011;55(6):2601-5.
2011: Glynn A Morrish; Manjunath P Pai; Bruce Green
The effects of obesity on drug pharmacokinetics in humans.
Expert opinion on drug metabolism & toxicology 2011;7(6):697-706.
2011: Nimish Patel; Manjunath P Pai; Keith A Rodvold; Ben Lomaestro; George L Drusano; Thomas P Lodise
Vancomycin: we can't get there from here.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2011;52(8):969-74.
2010: Manjunath P Pai
Estimating the glomerular filtration rate in obese adult patients for drug dosing.
Advances in chronic kidney disease 2010;17(5):e53-62.
2010: Manjunath P Pai; Hollie Bruce; Linda A Felton
Clinical pharmacokinetics of oral controlled-release 5-fluorocytosine.
Antimicrobial agents and chemotherapy 2010;54(3):1237-41.
2009: Manjunath P Pai
Antifungal combinations against simulated Candida albicans endocardial vegetations.
Antimicrobial agents and chemotherapy 2009;53(6):2629-31.
2009: Jasmina A Demirovic; Amy Barton Pai; Manjunath P Pai
Estimation of creatinine clearance in morbidly obese patients.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2009;66(7):642-8.
2009: Manjunath P Pai; Unal Sakoglu; Steven L Peterson; C Rick Lyons; Rohit Sood
Characterization of BBB permeability in a preclinical model of cryptococcal meningoencephalitis using magnetic resonance imaging.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(3):545-53.
2008: Manjunath P Pai; Marie L Samples; Renee-Claude Mercier; Michael N Spilde
Activities and ultrastructural effects of antifungal combinations against simulated Candida endocardial vegetations.
Antimicrobial agents and chemotherapy 2008;52(7):2367-76.
2007: Manjunath P Pai; David T Bearden
Antimicrobial dosing considerations in obese adult patients.
Pharmacotherapy 2007;27(8):1081-91.
2007: Manjunath P Pai; Jeffrey P Norenberg; Tamara Anderson; Diane W Goade; Keith A Rodvold; Robert A Telepak; Renee-Claude Mercier
Influence of morbid obesity on the single-dose pharmacokinetics of daptomycin.
Antimicrobial agents and chemotherapy 2007;51(8):2741-7.
2007: Kevin W Garey; Manjunath P Pai; Katie J Suda; Robin S Turpin; Milind D Rege; Dana E Mingo; David T Bearden
Inadequacy of fluconazole dosing in patients with candidemia based on Infectious Diseases Society of America (IDSA) guidelines.
Pharmacoepidemiology and drug safety 2007;16(8):919-27.
2007: Hua Chen; Katie J Suda; Robin S Turpin; Manjunath P Pai; David T Bearden; Kevin W Garey
High- versus low-dose fluconazole therapy for empiric treatment of suspected invasive candidiasis among high-risk patients in the intensive care unit: a cost-effectiveness analysis.
Current medical research and opinion 2007;23(5):1057-65.
2007: Kevin W Garey; Robin S Turpin; David T Bearden; Manjunath P Pai; Katie J Suda
Economic analysis of inadequate fluconazole therapy in non-neutropenic patients with candidaemia: a multi-institutional study.
International journal of antimicrobial agents 2007;29(5):557-62.
2007: Manjunath P Pai; Ariel L Jones; Casey K Mullen
Micafungin activity against Candida bloodstream isolates: effect of growth medium and susceptibility testing method.
Diagnostic microbiology and infectious disease 2007;58(1):129-32.
2007: Manjunath P Pai; Robin S Turpin; Kevin W Garey
Association of fluconazole area under the concentration-time curve/MIC and dose/MIC ratios with mortality in nonneutropenic patients with candidemia.
Antimicrobial agents and chemotherapy 2007;51(1):35-9.
2006: Manjunath P Pai; Kathryn M Momary; Keith A Rodvold
Antibiotic drug interactions.
The Medical clinics of North America 2006;90(6):1223-55.
2006: Manjunath P Pai; Sarah E Allen; Guy W Amsden
Altered steady state pharmacokinetics of levofloxacin in adult cystic fibrosis patients receiving calcium carbonate.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2006;5(3):153-7.
2006: Amy Barton Pai; Manjunath P Pai
Optimizing antimicrobial therapy for gram-positive bloodstream infections in patients on hemodialysis.
Advances in chronic kidney disease 2006;13(3):259-70.
2006: Kevin W Garey; Milind D Rege; Manjunath P Pai; Dana E Mingo; Katie J Suda; Robin S Turpin; David T Bearden
Time to initiation of fluconazole therapy impacts mortality in patients with candidemia: a multi-institutional study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;43(1):25-31.
2006: Manjunath P Pai; Renee-Claude Mercier; Sarah E Allen
Using vancomycin concentrations for dosing daptomycin in a morbidly obese patient with renal insufficiency.
The Annals of pharmacotherapy 2006;40(3):553-8.
2006: Manjunath P Pai; Renee-Claude Mercier; Sarah A Koster
Epidemiology of vancomycin-induced neutropenia in patients receiving home intravenous infusion therapy.
The Annals of pharmacotherapy 2006;40(2):224-8.
2006: Amy Barton Pai; Manjunath P Pai; Joseph Depczynski; Charles R McQuade; Renee-Claude Mercier
Non-transferrin-bound iron is associated with enhanced Staphylococcus aureus growth in hemodialysis patients receiving intravenous iron sucrose.
American journal of nephrology 2006;26(3):304-9.
2005: Manjunath P Pai; Jeffrey P Norenberg; Robert A Telepak; David S Sidney; Shu Yang
Assessment of effective renal plasma flow, enzymuria, and cytokine release in healthy volunteers receiving a single dose of amphotericin B desoxycholate.
Antimicrobial agents and chemotherapy 2005;49(9):3784-8.
2004: John W German; Susan M Kellie; Manjunath P Pai; Paul T Turner
Treatment of a chronic Scedosporium apiospermum vertebral osteomyelitis. Case report.
Neurosurgical focus 2004;17(6):E9.
2004: Kelly S Reed; Manjunath P Pai
Adjunctive granulocyte colony-stimulating factor therapy for diabetic foot infections.
The Annals of pharmacotherapy 2004;38(12):2150-3.
2004: Manjunath P Pai; Ariel L Jones
Altered susceptibility of Candida glabrata bloodstream isolates to triazoles at clinically relevant pH values: comparison of the NCCLS M27-A2, Sensititre YeastOne, and Etest methods.
Antimicrobial agents and chemotherapy 2004;48(11):4441-3.
2004: Amy Barton Pai; Manjunath P Pai
Vancomycin dosing in high flux hemodialysis: a limited-sampling algorithm.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2004;61(17):1812-6.
2004: A Christie Graham; Renee-Claude Mercier; Louis E Achusim; Manjunath P Pai
Extended-interval aminoglycoside dosing for treatment of enterococcal and staphylococcal osteomyelitis.
The Annals of pharmacotherapy 2004;38(6):936-41.
2004: Manjunath P Pai
Pharmacy education: beyond the basics.
Pharmacotherapy 2004;24(5):690-1; discussion 691-3.
2004: Manjunath P Pai; Christopher A Schriever; Mariela Diaz-Linares; Richard M Novak; Keith A Rodvold
Sex-related differences in the pharmacokinetics of once-daily saquinavir soft-gelatin capsules boosted with low-dose ritonavir in patients infected with human immunodeficiency virus type 1.
Pharmacotherapy 2004;24(5):592-9.
2003: Manjunath P Pai; Sarah Allen
Voriconazole inhibition of tacrolimus metabolism.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003;36(8):1089-91.
2003: Manjunath P Pai; Susan L Pendland
Antifungal susceptibility testing in teaching hospitals.
The Annals of pharmacotherapy 2003;37(2):192-6.
2002: Manjunath P Pai; Keith A Rodvold; Paul C Schreckenberger; Ronald D Gonzales; Jennifer M Petrolatti; John P Quinn
Risk factors associated with the development of infection with linezolid- and vancomycin-resistant Enterococcus faecium.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2002;35(10):1269-72.
2002: Donna M Kraus; Manjunath P Pai; Keith A Rodvold
Efficacy and tolerability of extended-interval aminoglycoside administration in pediatric patients.
Paediatric drugs 2002;4(7):469-84.
2001: Manjunath P Pai; Susan L Pendland; Larry H Danziger
Antimicrobial-coated/bonded and -impregnated intravascular catheters.
The Annals of pharmacotherapy 2001;35(10):1255-63.
2000: Manjunath P Pai; Frank P Paloucek
The origin of the "ideal" body weight equations.
The Annals of pharmacotherapy 2000;34(9):1066-9.
2000: Manjunath P Pai; DM Graci; J S Bertino
Waste generation of drug product samples versus prescriptions obtained through pharmacy dispensing.
Pharmacotherapy 2000;20(5):593-5.
2000: Manjunath P Pai; DM Graci; Guy W Amsden
Macrolide drug interactions: an update.
The Annals of pharmacotherapy 2000;34(4):495-513.