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Igor Berezovsky

Research Profile

Physiology

Protein Folding

Chemicals & Drugs

Genes & Molecular Sequences

Concepts & Ideas

Phenomena

Evolution, Molecular

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Computer Simulation

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Publications

TOP 3
Igor N Berezovsky
Thermodynamics of allostery paves a way to allosteric drugs.
Inbal Lasry; Jacob Levy; Ben Pode-Shakked; Young Ah Seo; Nechama Shalva; Igor N Berezovsky; Bluma Berman; Fabian Glaser; Alexander Goncearenco; Hadas Ityel; Shannon L Kelleher; Aharon Klar; Yair Anikster; Yehuda G Assaraf
A dominant negative heterozygous G87R mutation in the zinc transporter, ZnT-2 (SLC30A2), results in transient neonatal zinc deficiency.
Alexander Goncearenco; Igor N Berezovsky
Exploring the evolution of protein function in Archaea.

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All Publications

2013: Igor N Berezovsky
Thermodynamics of allostery paves a way to allosteric drugs.
Biochimica et biophysica acta 2013;1834(5):830-5.
2012: Inbal Lasry; Jacob Levy; Ben Pode-Shakked; Young Ah Seo; Nechama Shalva; Igor N Berezovsky; Bluma Berman; Fabian Glaser; Alexander Goncearenco; Hadas Ityel; Shannon L Kelleher; Aharon Klar; Yair Anikster; Yehuda G Assaraf
A dominant negative heterozygous G87R mutation in the zinc transporter, ZnT-2 (SLC30A2), results in transient neonatal zinc deficiency.
The Journal of biological chemistry 2012;287(35):29348-61.
2012: Alexander Goncearenco; Igor N Berezovsky
Exploring the evolution of protein function in Archaea.
BMC evolutionary biology 2012;12():75.
2011: Simon Mitternacht; Igor N Berezovsky
Binding leverage as a molecular basis for allosteric regulation.
PLoS computational biology 2011;7(9):e1002148.
2011: Alexander Goncearenco; Igor N Berezovsky
Computational reconstruction of primordial prototypes of elementary functional loops in modern proteins.
Bioinformatics (Oxford, England) 2011;27(17):2368-75.
2011: Igor N Berezovsky
The diversity of physical forces and mechanisms in intermolecular interactions.
Physical biology 2011;8(3):035002.
2011: Simon Mitternacht; Igor N Berezovsky
A geometry-based generic predictor for catalytic and allosteric sites.
Protein engineering, design & selection : PEDS 2011;24(4):405-9.
2011: Simon Mitternacht; Igor N Berezovsky
On the importance of amino acid sequence and spatial proximity of interacting residues for protein folding.
Journal of biomolecular structure & dynamics 2011;28(4):607-9; discussion 669-674.
2010: Bin-Guang Ma; Igor N Berezovsky
The MBLOSUM: a server for deriving mutation targets and position-specific substitution rates.
Journal of biomolecular structure & dynamics 2010;28(3):415-9.
2010: Alexander Goncearenco; Igor N Berezovsky
Prototypes of elementary functional loops unravel evolutionary connections between protein functions.
Bioinformatics (Oxford, England) 2010;26(18):i497-503.
2010: Bin-Guang Ma; Alexander Goncearenco; Igor N Berezovsky
Thermophilic adaptation of protein complexes inferred from proteomic homology modeling.
Structure (London, England : 1993) 2010;18(7):819-28.
2009: Nobuhiko Tokuriki; Christopher J Oldfield; Vladimir Uversky; Igor N Berezovsky; Dan S Tawfik
Do viral proteins possess unique biophysical features?
Trends in biochemical sciences 2009;34(2):53-9.
2008: Grzegorz Koczyk; Igor N Berezovsky
Domain Hierarchy and closed Loops (DHcL): a server for exploring hierarchy of protein domain structure.
Nucleic acids research 2008;36(Web Server issue):W239-45.
2007: Igor N Berezovsky; Konstantin B Zeldovich; Eugene I Shakhnovich
Positive and negative design in stability and thermal adaptation of natural proteins.
PLoS computational biology 2007;3(3):e52.
2007: Konstantin B Zeldovich; Igor N Berezovsky; Eugene I Shakhnovich
Protein and DNA sequence determinants of thermophilic adaptation.
PLoS computational biology 2007;3(1):e5.
2006: Konstantin B Zeldovich; Igor N Berezovsky; Eugene I Shakhnovich
Physical origins of protein superfamilies.
Journal of molecular biology 2006;357(4):1335-43.
2005: Igor N Berezovsky; Eugene I Shakhnovich
Physics and evolution of thermophilic adaptation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(36):12742-7.
2005: Igor N Berezovsky; William W Chen; Paul J Choi; Eugene I Shakhnovich
Entropic stabilization of proteins and its proteomic consequences.
PLoS computational biology 2005;1(4):e47.
2004: Nikolaos Papandreou; Igor N Berezovsky; Anne Lopes; Elias Eliopoulos; Jacques Chomilier
Universal positions in globular proteins.
European journal of biochemistry / FEBS 2004;271(23-24):4762-8.
2003: Igor N Berezovsky; Alla Kirzhner; Valery Kirzhner; Edward N Trifonov
Spelling protein structure.
Journal of biomolecular structure & dynamics 2003;21(3):327-39.
2003: Igor N Berezovsky; Alla Kirzhner; Valery Kirzhner; Vladimir R Rosenfeld; Edward N Trifonov
Protein sequences yield a proteomic code.
Journal of biomolecular structure & dynamics 2003;21(3):317-25.
2003: Igor N Berezovsky
Discrete structure of van der Waals domains in globular proteins.
Protein engineering 2003;16(3):161-7.
2003: Edward N Trifonov; Igor N Berezovsky
Evolutionary aspects of protein structure and folding.
Current opinion in structural biology 2003;13(1):110-4.
2002: Igor N Berezovsky; Valery Kirzhner; Alla Kirzhner; Vladimir R Rosenfeld; Edward N Trifonov
Closed loops: persistence of the protein chain returns.
Protein engineering 2002;15(12):955-7.
2002: Igor N Berezovsky; Edward N Trifonov
Back to units of protein folding.
Journal of biomolecular structure & dynamics 2002;20(3):315-6.
2002: Edward N Trifonov; Igor N Berezovsky
Molecular evolution from abiotic scratch.
FEBS letters 2002;527(1-3):1-4.
2002: Igor N Berezovsky; Edward N Trifonov
Loop fold structure of proteins: resolution of Levinthas paradox.
Journal of biomolecular structure & dynamics 2002;20(1):5-6.
2002: Edward N Trifonov; Igor N Berezovsky
[Proteomic code].
Molekuliarnaia biologiia 2002;36(2):315-9.
2002: Igor N Berezovsky; Edward N Trifonov
Flowering buds of globular proteins: transpiring simplicity of protein organization.
Comparative and functional genomics 2002;3(6):525-34.
2001: Igor N Berezovsky; Valery Kirzhner; Alla Kirzhner; Edward N Trifonov
Protein folding: looping from hydrophobic nuclei.
Proteins 2001;45(4):346-50.
2001: Edward N Trifonov; Alla Kirzhner; Valery Kirzhner; Igor N Berezovsky
Distinct stages of protein evolution as suggested by protein sequence analysis.
Journal of molecular evolution 2001;53(4-5):394-401.
2001: Igor N Berezovsky; Edward N Trifonov
Loop fold nature of globular proteins.
Protein engineering 2001;14(6):403-7.
2001: Igor N Berezovsky; Edward N Trifonov
Van der Waals locks: loop-n-lock structure of globular proteins.
Journal of molecular biology 2001;307(5):1419-26.
2000: Igor N Berezovsky; Natalia G Esipova; Vladimir G Tumanyan; VA Namiot
A new approach for the calculation of the energy of van der Waals interactions in macromolecules of globular proteins.
Journal of biomolecular structure & dynamics 2000;17(5):799-809.
2000: Igor N Berezovsky; Natalia G Esipova; Vladimir G Tumanyan
Hierarchy of regions of amino acid sequence with respect to their role in the protein spatial structure.
Journal of computational biology : a journal of computational molecular cell biology 2000;7(1-2):183-92.
2000: Igor N Berezovsky; A Y Grosberg; Edward N Trifonov
Closed loops of nearly standard size: common basic element of protein structure.
FEBS letters 2000;466(2-3):283-6.
1999: Igor N Berezovsky; VA Namiot; Vladimir G Tumanyan; Natalia G Esipova
Hierarchy of the interaction energy distribution in the spatial structure of globular proteins and the problem of domain definition.
Journal of biomolecular structure & dynamics 1999;17(1):133-55.
1999: Igor N Berezovsky; Gelena T Kilosanidze; Vladimir G Tumanyan; Lev L Kisselev
Amino acid composition of protein termini are biased in different manners.
Protein engineering 1999;12(1):23-30.
1997: Igor N Berezovsky; Vladimir G Tumanyan; Natalia G Esipova
Representation of amino acid sequences in terms of interaction energy in protein globules.
FEBS letters 1997;418(1-2):43-6.
1997: Igor N Berezovsky; Gelena T Kilosanidze; Vladimir G Tumanyan; Lev L Kisselev
COOH-terminal decamers in proteins are non-random.
FEBS letters 1997;404(2-3):140-2.