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Chang Paik

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TOP 3
Shutao Wang; Vesna Zderic; Victor Frenkel; Hilary Hancock; Beom-Su Jang; Hyung-sub Kim; Sang Myung Lee; Chang H Paik; Ira Pastan; In Soo Shin; Matthew R Dreher
Pulsed high intensity focused ultrasound increases penetration and therapeutic efficacy of monoclonal antibodies in murine xenograft tumors.
Beom-Su Jang; Hyung Sub Kim; Sang-Myung Lee; Ira Pastan; Faezeh Razjouyan; In Soo Shin; Shutao Wang; Zhengsheng Yao; Matthew R Dreher; Chang H Paik
Combined-modality radioimmunotherapy: synergistic effect of paclitaxel and additive effect of bevacizumab.
In Soo Shin; Zhengsheng Yao; Ira Pastan; Celeste Regino; Noriko Sato; Earl F Albone; Melissa F Campo; Kenneth T Cheng; Peter L Choyke; Raffit Hassan; Hyung Sub Kim; Sang-Myung Lee; Chang H Paik
Effect of chelator conjugation level and injection dose on tumor and organ uptake of 111In-labeled MORAb-009, an anti-mesothelin antibody.

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All Publications

2012: Shutao Wang; Vesna Zderic; Victor Frenkel; Hilary Hancock; Beom-Su Jang; Hyung-sub Kim; Sang Myung Lee; Chang H Paik; Ira Pastan; In Soo Shin; Matthew R Dreher
Pulsed high intensity focused ultrasound increases penetration and therapeutic efficacy of monoclonal antibodies in murine xenograft tumors.
Journal of controlled release : official journal of the Controlled Release Society 2012;162(1):218-24.
2012: Beom-Su Jang; Hyung Sub Kim; Sang-Myung Lee; Ira Pastan; Faezeh Razjouyan; In Soo Shin; Shutao Wang; Zhengsheng Yao; Matthew R Dreher; Chang H Paik
Combined-modality radioimmunotherapy: synergistic effect of paclitaxel and additive effect of bevacizumab.
Nuclear medicine and biology 2012;39(4):472-83.
2011: In Soo Shin; Zhengsheng Yao; Ira Pastan; Celeste Regino; Noriko Sato; Earl F Albone; Melissa F Campo; Kenneth T Cheng; Peter L Choyke; Raffit Hassan; Hyung Sub Kim; Sang-Myung Lee; Chang H Paik
Effect of chelator conjugation level and injection dose on tumor and organ uptake of 111In-labeled MORAb-009, an anti-mesothelin antibody.
Nuclear medicine and biology 2011;38(8):1119-27.
2010: Nobuyuki Kosaka; Mikako Ogawa; David S Paik; Chang H Paik; Peter L Choyke; Hisataka Kobayashi
Semiquantitative assessment of the microdistribution of fluorescence-labeled monoclonal antibody in small peritoneal disseminations of ovarian cancer.
Cancer science 2010;101(3):820-5.
2009: Michele Di Mascio; Chang H Paik; Jorge Carrasquillo; Jin-Soo Maeng; Beom-Su Jang; In Soo Shin; Sharat Srinivasula; Russ Byrum; Achilles Neria; William Kopp; Marta Catalfamo; Yoshiaki Nishimura; Keith Reimann; Malcolm Martin; H Clifford Lane
Noninvasive in vivo imaging of CD4 cells in simian-human immunodeficiency virus (SHIV)-infected nonhuman primates.
Blood 2009;114(2):328-37.
2009: Meili Zhang; Zhengsheng Yao; Kayhan Garmestani; Sarah Yu; Carolyn K Goldman; Chang H Paik; Martin W Brechbiel; Jorge Carrasquillo; Thomas Waldmann
Preclinical evaluation of an anti-CD25 monoclonal antibody, 7G7/B6, armed with the beta-emitter, yttrium-90, as a radioimmunotherapeutic agent for treating lymphoma.
Cancer biotherapy & radiopharmaceuticals 2009;24(3):303-9.
2008: Mala Chakraborty; Alexander Gelbard; Jorge Carrasquillo; Sarah Yu; Marcelo Mamede; Chang H Paik; Kevin A Camphausen; Jeffrey Schlom; James W Hodge
Use of radiolabeled monoclonal antibody to enhance vaccine-mediated antitumor effects.
Cancer immunology, immunotherapy : CII 2008;57(8):1173-83.
2008: Alfia Khaibullina; Beom-Su Jang; Haihao Sun; Nhat Le; Sarah Yu; Victor Frenkel; Jorge Carrasquillo; Ira Pastan; King Li; Chang H Paik
Pulsed high-intensity focused ultrasound enhances uptake of radiolabeled monoclonal antibody to human epidermoid tumor in nude mice.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(2):295-302.
2007: Tristan Barrett; Yoshinori Koyama; Yukihiro Hama; Gregory Ravizzini; In Soo Shin; Beom-Su Jang; Chang H Paik; Yasuteru Urano; Peter L Choyke; Hisataka Kobayashi
In vivo diagnosis of epidermal growth factor receptor expression using molecular imaging with a cocktail of optically labeled monoclonal antibodies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(22 Pt 1):6639-48.
2007: Hisataka Kobayashi; Yoshinori Koyama; Tristan Barrett; Yukihiro Hama; Celeste A S Regino; In Soo Shin; Beom-Su Jang; Nhat Le; Chang H Paik; Peter L Choyke; Yasuteru Urano
Multimodal nanoprobes for radionuclide and five-color near-infrared optical lymphatic imaging.
ACS nano 2007;1(4):258-64.
2007: Beom-Su Jang; Esther Lim; Seung Hee Park; In Soo Shin; S Narasimhan Danthi; In Sook Hwang; Nhat Le; Sarah Yu; Jianwu Xie; King Li; Jorge Carrasquillo; Chang H Paik
Radiolabeled high affinity peptidomimetic antagonist selectively targets alpha(v)beta(3) receptor-positive tumor in mice.
Nuclear medicine and biology 2007;34(4):363-70.
2007: In Soo Shin; Beom-Su Jang; S Narasimhan Danthi; Jianwu Xie; Sarah Yu; Nhat Le; Jin-Soo Maeng; In Sook Hwang; King Li; Jorge Carrasquillo; Chang H Paik
Use of antibody as carrier of oligomers of peptidomimetic alphavbeta3 antagonist to target tumor-induced neovasculature.
Bioconjugate chemistry 2007;18(3):821-8.
2007: Yukihiro Hama; Yasuteru Urano; Yoshinori Koyama; Mako Kamiya; Marcelino Bernardo; Ronald S Paik; In Soo Shin; Chang H Paik; Peter L Choyke; Hisataka Kobayashi
A target cell-specific activatable fluorescence probe for in vivo molecular imaging of cancer based on a self-quenched avidin-rhodamine conjugate.
Cancer research 2007;67(6):2791-9.
2006: Meili Zhang; Zhengsheng Yao; Zhuo Zhang; Kayhan Garmestani; Vladimir S Talanov; Paul S Plascjak; Sarah Yu; Hyung-Sik Kim; Carolyn K Goldman; Chang H Paik; Martin W Brechbiel; Jorge Carrasquillo; Thomas Waldmann
The anti-CD25 monoclonal antibody 7G7/B6, armed with the alpha-emitter 211At, provides effective radioimmunotherapy for a murine model of leukemia.
Cancer research 2006;66(16):8227-32.
2006: yujian zhang; Laiman Xiang; Raffit Hassan; Chang H Paik; Jorge Carrasquillo; Beom-Su Jang; Nhat Le; Mitchell Ho; Ira Pastan
Synergistic antitumor activity of taxol and immunotoxin SS1P in tumor-bearing mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(15):4695-701.
2005: Noriko Sato; Raffit Hassan; Axworthy Don; Karen J Wong; Sarah Yu; Louis J Theodore; Yukang Lin; Luke Park; Martin W Brechbiel; Ira Pastan; Chang H Paik; Jorge Carrasquillo
Pretargeted radioimmunotherapy of mesothelin-expressing cancer using a tetravalent single-chain Fv-streptavidin fusion protein.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(7):1201-9.
2004: Zhengsheng Yao; Meili Zhang; Kayhan Garmestani; Axworthy Don; Robert W Mallett; Alan R Fritzberg; Louis J Theodore; Paul S Plascjak; William Eckelman; Thomas Waldmann; Ira Pastan; Chang H Paik; Martin W Brechbiel; Jorge Carrasquillo
Pretargeted alpha emitting radioimmunotherapy using (213)Bi 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid-biotin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(9):3137-46.
2004: Luke S Park; Lawrence P Szajek; Karen J Wong; Paul S Plascjak; Kayhan Garmestani; Shawn Googins; William Eckelman; Jorge Carrasquillo; Chang H Paik
Semi-automated 86Y purification using a three-column system.
Nuclear medicine and biology 2004;31(2):297-301.
2003: Noriko Sato; Chang W Park; Hyung-Sik Kim; Eui-sik Han; Karen J Wong; Ronald S Paik; Luke S Park; Zhengsheng Yao; Jorge Carrasquillo; Chang H Paik
Synthesis of dendrimer-based biotin radiopharmaceuticals to enhance whole-body clearance.
Nuclear medicine and biology 2003;30(6):617-25.
2002: Insook Kim; Hisataka Kobayashi; Tae M Yoo; Meyong-kon Kim; Nhat Le; Eui-sik Han; Qing-Cheng Wang; Ira Pastan; Jorge Carrasquillo; Chang H Paik
Lowering of pI by acylation improves the renal uptake of 99mTc-labeled anti-Tac dsFv: effect of different acylating reagents.
Nuclear medicine and biology 2002;29(8):795-801.
2002: Zhengsheng Yao; Meili Zhang; Axworthy Don; Karen J Wong; Kayhan Garmestani; Luke Park; Chang W Park; Robert W Mallett; Louis J Theodore; Eric K Yau; Thomas Waldmann; Martin W Brechbiel; Chang H Paik; Ira Pastan; Jorge Carrasquillo
Radioimmunotherapy of A431 xenografted mice with pretargeted B3 antibody-streptavidin and (90)Y-labeled 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid (DOTA)-biotin.
Cancer research 2002;62(20):5755-60.
2002: Meyoung-Kon Kim; Hyeh-Jean Jeong; Chih-Hao K Kao; Zhengsheng Yao; David S Paik; Jae-Eun Pie; Hisataka Kobayashi; Thomas Waldmann; Jorge Carrasquillo; Chang H Paik
Improved renal clearance and tumor targeting of 99mTc-labeled anti-Tac monoclonal antibody Fab by chemical modifications.
Nuclear medicine and biology 2002;29(2):139-46.
2001: Zhengsheng Yao; Kayhan Garmestani; Karen J Wong; Luke S Park; Ekaterina Dadachova; Alexander T Yordanov; Thomas Waldmann; William Eckelman; Chang H Paik; Jorge Carrasquillo
Comparative cellular catabolism and retention of astatine-, bismuth-, and lead-radiolabeled internalizing monoclonal antibody.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2001;42(10):1538-44.
2001: Ekaterina Dadachova; C Park; N Eberly; Dangshe Ma; Chang H Paik; Martin W Brechbiel
In vitro and in vivo characterization of 67Ga(3+) complexes with cis,cis-1,3,5-triamino-cyclohexane-N,N',N"-triacetic acid derivatives.
Nuclear medicine and biology 2001;28(6):695-701.
2000: Hisataka Kobayashi; Jorge Carrasquillo; Chang H Paik; Thomas Waldmann; Yutaka Tagaya
Differences of biodistribution, pharmacokinetics, and tumor targeting between interleukins 2 and 15.
Cancer research 2000;60(13):3577-83.
2000: Valeri N Karamychev; Igor G Panyutin; Meyoung-Kon Kim; Nhat Le; Chang H Paik; Jorge Carrasquillo; MW Reed; Ronald D Neumann
DNA cleavage by 111In-labeled oligodeoxyribonucleotides.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(6):1093-101.
2000: Lee Pai-Scherf; Jorge Carrasquillo; Chang H Paik; Otto A Gansow; Millie Whatley; D Pearson; KO Webber; Michael Hamilton; Carmen J Allegra; Martin W Brechbiel; Mark C Willingham; Ira Pastan
Imaging and phase I study of 111In- and 90Y-labeled anti-LewisY monoclonal antibody B3.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(5):1720-30.
2000: Hisataka Kobayashi; C H Kao; Robert J Kreitman; Nhat Le; Meyoung-Kon Kim; Martin W Brechbiel; Chang H Paik; Ira Pastan; Jorge Carrasquillo
Pharmacokinetics of 111In- and 125I-labeled antiTac single-chain Fv recombinant immunotoxin.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(4):755-62.
2000: BF Sun; Hisataka Kobayashi; Nhat Le; Tae M Yoo; D Drumm; Chang H Paik; J G McAfee; Jorge Carrasquillo
Effects of insulinlike growth factor binding proteins on insulinlike growth factor-I biodistribution in tumor-bearing nude mice.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(2):318-26.
1999: H Kobayashi; Yutaka Tagaya; E S Han; I S Kim; N Le; Chang H Paik; Ira Pastan; D L Nelson; Thomas Waldmann; Jorge Carrasquillo
Use of an antibody against the soluble interleukin 2 receptor alpha subunit can modulate the stability and biodistribution of interleukin-2.
Cytokine 1999;11(12):1065-75.
1999: Hisataka Kobayashi; BF Sun; Tae M Yoo; Nhat Le; Meyoung-Kon Kim; Chang H Paik; Ira Pastan; Thomas Waldmann; Jorge Carrasquillo
Methods to avoid adverse effect of circulating antigen on biodistribution of 125I-labeled antiTac dsFv: preinjection of intact antibody versus clearance of antigen with adivin-biotin system.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(8):1381-91.
1999: IS Kim; Tae M Yoo; Hisataka Kobayashi; Meyoung-Kon Kim; Nhat Le; Qing-Cheng Wang; Ira Pastan; Jorge Carrasquillo; Chang H Paik
Chemical modification to reduce renal uptake of disulfide-bonded variable region fragment of anti-Tac monoclonal antibody labeled with 99mTc.
Bioconjugate chemistry 1999;10(3):447-53.
1999: Hisataka Kobayashi; IS Kim; D Drumm; Meyoung-Kon Kim; David S Paik; Nhat Le; Thomas Waldmann; Jorge Carrasquillo; Chang H Paik
Favorable effects of glycolate conjugation on the biodistribution of humanized antiTac Fab fragment.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(5):837-45.
1999: M C Chakrabarti; Chang H Paik; Jorge Carrasquillo
Preparation and in vitro studies of [125I]IUDR-T101 antibody conjugate.
Cancer biotherapy & radiopharmaceuticals 1999;14(2):91-8.
1999: Jorge Carrasquillo; Jeffrey D White; Chang H Paik; Andrew Raubitschek; Nhat Le; M Rotman; Martin W Brechbiel; Otto A Gansow; Lois E Top; P Perentesis; James C Reynolds; David L Nelson; Thomas Waldmann
Similarities and differences in 111In- and 90Y-labeled 1B4M-DTPA antiTac monoclonal antibody distribution.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(2):268-76.
1999: Hisataka Kobayashi; Nhat Le; IS Kim; Meyoung-Kon Kim; Jae-Eun Pie; D Drumm; David S Paik; Thomas Waldmann; Chang H Paik; Jorge Carrasquillo
The pharmacokinetic characteristics of glycolated humanized anti-Tac Fabs are determined by their isoelectric points.
Cancer research 1999;59(2):422-30.
1999: M Kim; Jurgen Seidel; Nhat Le; IS Kim; Tae M Yoo; C Barker; Hisataka Kobayashi; Michael V Green; Jorge Carrasquillo; Chang H Paik
Evaluation of 99mTc-mercaptoacetyltriglycine-biocytin as a new hepatobiliary imaging agent in mice coinjected with bilirubin.
Nuclear medicine and biology 1999;26(1):43-9.
1999: Hisataka Kobayashi; Carl Wu; M K Kim; Chang H Paik; Jorge Carrasquillo; Martin W Brechbiel
Evaluation of the in vivo biodistribution of indium-111 and yttrium-88 labeled dendrimer-1B4M-DTPA and its conjugation with anti-Tac monoclonal antibody.
Bioconjugate chemistry 1999;10(1):103-11.
1998: F M Foss; A Raubitscheck; James L Mulshine; Thomas A Fleisher; James C Reynolds; Chang H Paik; Ronald D Neumann; C Boland; P Perentesis; M R Brown; J M Frincke; C P Lollo; Steven M Larson; Jorge Carrasquillo
Phase I study of the pharmacokinetics of a radioimmunoconjugate, 90Y-T101, in patients with CD5-expressing leukemia and lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(11):2691-700.
1998: Meyoung-Kon Kim; Byoung J Song; Jurgen Seidel; Y Soh; Kyu-Shik Jeong; IS Kim; Hisataka Kobayashi; Michael V Green; Jorge Carrasquillo; Chang H Paik
Use of 99mTc-mercaptoacetyltriglycine (MAG3)-biocytin hepatobiliary scintigraphy to study the protective effect of a synthetic enzyme inhibitor on acute hepatotoxicity in mice.
Nuclear medicine and biology 1998;25(6):561-8.
1998: Hisataka Kobayashi; Eui-sik Han; IS Kim; Nhat Le; V Rajagopal; Robert J Kreitman; Ira Pastan; Chang H Paik; Jorge Carrasquillo
Similarities in the biodistribution of iodine-labeled anti-Tac single-chain disulfide-stabilized Fv fragment and anti-Tac disulfide-stabilized Fv fragment.
Nuclear medicine and biology 1998;25(4):387-93.
1998: Hisataka Kobayashi; Chuanchu Wu; Tae M Yoo; BF Sun; D Drumm; Ira Pastan; Chang H Paik; Otto A Gansow; Jorge Carrasquillo; Martin W Brechbiel
Evaluation of the in vivo biodistribution of yttrium-labeled isomers of CHX-DTPA-conjugated monoclonal antibodies.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(5):829-36.
1998: Hisataka Kobayashi; BF Sun; Eui-sik Han; Meyoung-Kon Kim; Nhat Le; Qing-Cheng Wang; David L Nelson; Ira Pastan; Thomas Waldmann; Chang H Paik; Jorge Carrasquillo
Epitope blocking: positive and negative effects on the biodistribution of 125I-labeled anti-Tac disulfide-stabilized Fv fragment of two antibodies against different epitopes of the circulating antigen.
Japanese journal of cancer research : Gann 1998;89(4):436-44.
1997: Chuanchu Wu; Hisataka Kobayashi; B Sun; Tae M Yoo; Chang H Paik; Otto A Gansow; Jorge Carrasquillo; Ira Pastan; Martin W Brechbiel
Stereochemical influence on the stability of radio-metal complexes in vivo. Synthesis and evaluation of the four stereoisomers of 2-(p-nitrobenzyl)-trans-CyDTPA.
Bioorganic & medicinal chemistry 1997;5(10):1925-34.
1997: BF Sun; Hisataka Kobayashi; Nhat Le; Tae M Yoo; D Drumm; Chang H Paik; J G McAfee; Jorge Carrasquillo
Biodistribution of 125I-labeled des(1-3) insulin-like growth factor I in tumor-bearing nude mice and its in vitro catabolism.
Cancer research 1997;57(13):2754-9.
1997: Lixin Lang; Elaine M Jagoda; Chuanchu Wu; Martin W Brechbiel; Otto A Gansow; Ira Pastan; Chang H Paik; Jorge Carrasquillo; William Eckelman
Factors influencing the in vivo pharmacokinetics of peptides and antibody fragments: the pharmacokinetics of two PET-labeled low molecular weight proteins.
The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR) 1997;41(2):53-61.
1997: Hisataka Kobayashi; Tae M Yoo; D Drumm; Meyoung-Kon Kim; BF Sun; Nhat Le; KO Webber; Ira Pastan; Thomas Waldmann; Chang H Paik; Jorge Carrasquillo
Improved biodistribution of 125I-labeled anti-Tac disulfide-stabilized Fv fragment by blocking its binding to the alpha subunit of the interleukin 2 receptor in the circulation with preinjected humanized anti-Tac IgG.
Cancer research 1997;57(10):1955-61.
1997: J Lee; Kayhan Garmestani; Chuanchu Wu; Martin W Brechbiel; H K Chang; C W Choi; Otto A Gansow; Jorge Carrasquillo; Chang H Paik
In vitro and in vivo evaluation of structure-stability relationship of 111In- and 67Ga-labeled antibody via 1B4M or C-NOTA chelates.
Nuclear medicine and biology 1997;24(3):225-30.
1997: Tae M Yoo; H K Chang; C W Choi; KO Webber; Nhat Le; IS Kim; William Eckelman; Ira Pastan; Jorge Carrasquillo; Chang H Paik
Technetium-99m labeling and biodistribution of anti-TAC disulfide-stabilized Fv fragment.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(2):294-300.
1996: Hisataka Kobayashi; Tae M Yoo; IS Kim; Meyoung-Kon Kim; Nhat Le; KO Webber; Ira Pastan; Chang H Paik; William Eckelman; Jorge Carrasquillo
L-lysine effectively blocks renal uptake of 125I- or 99mTc-labeled anti-Tac disulfide-stabilized Fv fragment.
Cancer research 1996;56(16):3788-95.
1996: Lixin Lang; Luigi Aloj; Dale O Kiesewetter; Elaine M Jagoda; J T Lee; Chang H Paik; Jorge Carrasquillo; William Eckelman
A review of new oncotropic tracers for PET imaging.
Nuclear medicine and biology 1996;23(6):669-72.
1996: M C Chakrabarti; Nhat Le; Chang H Paik; W G De Graff; Jorge Carrasquillo
Prevention of radiolysis of monoclonal antibody during labeling.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(8):1384-8.
1996: B Yu; Jorge Carrasquillo; Diane E Milenic; Y Chung; P Perentesis; I Feuerestein; D Eggensperger; C F Qi; Chang H Paik; J Reynolds; Jean L Grem; G Curt; K Siler; Jeffrey Schlom; Carmen J Allegra
Phase I trial of iodine 131-labeled COL-1 in patients with gastrointestinal malignancies: influence of serum carcinoembryonic antigen and tumor bulk on pharmacokinetics.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(6):1798-809.
1995: T Mulligan; Jorge Carrasquillo; Y Chung; Diane E Milenic; Jeffrey Schlom; I Feuerstein; Chang H Paik; P Perentesis; J Reynolds; G Curt
Phase I study of intravenous Lu-labeled CC49 murine monoclonal antibody in patients with advanced adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(12):1447-54.
1995: Thomas Waldmann; Jeffrey D White; Jorge Carrasquillo; James C Reynolds; Chang H Paik; Otto A Gansow; Martin W Brechbiel; Elaine S Jaffe; Thomas A Fleisher; Carolyn K Goldman; Lois E Top; RN Bamford; E Zaknoen; E Roessler; C Kasten-Sportes; R England; H Litou; J A Johnson; T Jackson-White; Angela Manns; Barrie Hanchard; Richard P. Junghans; David L Nelson
Radioimmunotherapy of interleukin-2R alpha-expressing adult T-cell leukemia with Yttrium-90-labeled anti-Tac.
Blood 1995;86(11):4063-75.
1995: C W Choi; Lixin Lang; J T Lee; KO Webber; Tae M Yoo; H K Chang; Nhat Le; Elaine M Jagoda; Chang H Paik; Ira Pastan
Biodistribution of 18F- and 125I-labeled anti-Tac disulfide-stabilized Fv fragments in nude mice with interleukin 2 alpha receptor-positive tumor xenografts.
Cancer research 1995;55(22):5323-9.
1995: T Saga; Ronald D Neumann; T Heya; J Sato; S Kinuya; Nhat Le; Chang H Paik; John N Weinstein
Targeting cancer micrometastases with monoclonal antibodies: a binding-site barrier.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(19):8999-9003.
1995: J Lee; Chang H Paik; Dale O Kiesewetter; S G Park; William Eckelman
Evaluation of stereoisomers of 4-fluoroalkyl analogues of 3-quinuclidinyl benzilate in in vivo competition studies for the M1, M2, and M3 muscarinic receptor subtypes in brain.
Nuclear medicine and biology 1995;22(6):773-81.
1995: Y Hiramatsu; William Eckelman; Jorge Carrasquillo; R S Miletich; I H Valdez; R H Kurrasch; A A Macynski; Chang H Paik; R D Neumann; Bruce J Baum
Kinetic analysis of muscarinic receptors in human brain and salivary gland in vivo.
The American journal of physiology 1995;268(6 Pt 2):R1491-9.
1995: T Bakács; J Lee; M B Moreno; C M Zacharchuk; MS Cole; JY Tso; Chang H Paik; J M Ward; David M Segal
A bispecific antibody prolongs survival in mice bearing lung metastases of syngeneic mammary adenocarcinoma.
International immunology 1995;7(6):947-55.
1995: M B Moreno; J A Titus; MS Cole; JY Tso; Nhat Le; Chang H Paik; T Bakács; C M Zacharchuk; David M Segal; John R Wunderlich
Bispecific antibodies retarget murine T cell cytotoxicity against syngeneic breast cancer in vitro and in vivo.
Cancer immunology, immunotherapy : CII 1995;40(3):182-90.
1995: Dale O Kiesewetter; J Lee; Lixin Lang; S G Park; Chang H Paik; William Eckelman
Preparation of 18F-labeled muscarinic agonist with M2 selectivity.
Journal of medicinal chemistry 1995;38(1):5-8.
1994: S Kinuya; J M Jeong; Kayhan Garmestani; T Saga; L Camera; Martin W Brechbiel; Otto A Gansow; Jorge Carrasquillo; Ronald D Neumann; Chang H Paik
Effect of metabolism on retention of indium-111-labeled monoclonal antibody in liver and blood.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1994;35(11):1851-7.
1994: J M Jeong; S Kinuya; Chang H Paik; T Saga; V K Sood; Jorge Carrasquillo; Ronald D Neumann; J C Reynolds
Application of high affinity binding concept to radiolabel avidin with Tc-99m labeled biotin and the effect of pI on biodistribution.
Nuclear medicine and biology 1994;21(7):935-40.
1994: L Camera; S Kinuya; Kayhan Garmestani; Martin W Brechbiel; Chuanchu Wu; L H Pai; T J McMurry; Otto A Gansow; Ira Pastan; Chang H Paik
Comparative biodistribution of indium- and yttrium-labeled B3 monoclonal antibody conjugated to either 2-(p-SCN-Bz)-6-methyl-DTPA (1B4M-DTPA) or 2-(p-SCN-Bz)-1,4,7,10-tetraazacyclododecane tetraacetic acid (2B-DOTA).
European journal of nuclear medicine 1994;21(7):640-6.
1994: L Camera; S Kinuya; Kayhan Garmestani; Chuanchu Wu; Martin W Brechbiel; L H Pai; T J McMurry; Otto A Gansow; Ira Pastan; Chang H Paik
Evaluation of the serum stability and in vivo biodistribution of CHX-DTPA and other ligands for yttrium labeling of monoclonal antibodies.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1994;35(5):882-9.
1994: T Saga; John N Weinstein; J M Jeong; T Heya; J T Lee; Nhat Le; Chang H Paik; Cynthia Sung; Ronald D Neumann
Two-step targeting of experimental lung metastases with biotinylated antibody and radiolabeled streptavidin.
Cancer research 1994;54(8):2160-5.
1993: CS John; Wayne D Bowen; T Saga; S Kinuya; BJ Vilner; J Baumgold; Chang H Paik; Richard C Reba; R D Neumann; V M Varma
A malignant melanoma imaging agent: synthesis, characterization, in vitro binding and biodistribution of iodine-125-(2-piperidinylaminoethyl)4-iodobenzamide.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(12):2169-75.
1993: L Camera; S Kinuya; Kayhan Garmestani; L H Pai; Martin W Brechbiel; Otto A Gansow; Chang H Paik; Ira Pastan; Jorge Carrasquillo
Evaluation of a new DTPA-derivative chelator: comparative biodistribution and imaging studies of 111In-labeled B3 monoclonal antibody in athymic mice bearing human epidermoid carcinoma xenografts.
Nuclear medicine and biology 1993;20(8):955-62.
1993: L Camera; S Kinuya; L H Pai; Kayhan Garmestani; Martin W Brechbiel; Otto A Gansow; Chang H Paik; Ira Pastan; Jorge Carrasquillo
Preclinical evaluation of 111In-labeled B3 monoclonal antibody: biodistribution and imaging studies in nude mice bearing human epidermoid carcinoma xenografts.
Cancer research 1993;53(12):2834-9.
1993: M Juweid; J Sato; Chang H Paik; S Onay-Basaran; John N Weinstein; Ronald D Neumann
A simple method for affinity purification of radiolabeled monoclonal antibodies.
Nuclear medicine and biology 1993;20(3):311-5.
1993: CS John; S Kinuya; G Minear; R K Keast; Chang H Paik
Synthesis and biological evaluation of gallium polyaminothiols (PAT).
Nuclear medicine and biology 1993;20(2):217-23.
1993: CS John; T Saga; S Kinuya; Nhat Le; J M Jeong; Chang H Paik; Richard C Reba; V M Varma; J G McAfee
An improved synthesis of [125I]N-(diethylaminoethyl)-4-iodobenzamide: a potential ligand for imaging malignant melanoma.
Nuclear medicine and biology 1993;20(1):75-9.
1992: M Juweid; R Neumann; Chang H Paik; M J Perez-Bacete; J Sato; W van Osdol; John N Weinstein
Micropharmacology of monoclonal antibodies in solid tumors: direct experimental evidence for a binding site barrier.
Cancer research 1992;52(19):5144-53.
1992: Chang H Paik; V K Sood; Nhat Le; L Cioloca; Jorge Carrasquillo; James C Reynolds; Ronald D Neumann; Richard C Reba
Radiolabeled products in rat liver and serum after administration of antibody-amide-DTPA-indium-111.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1992;19(5):517-22.
1992: CS John; E O Schlemper; P Hosain; Chang H Paik; Richard C Reba
Synthesis, characterization and biodistribution of a new hexadentate aminethiol ligand labeled with Tc-99m.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1992;19(3):269-74.
1990: K Yokoyama; James C Reynolds; Chang H Paik; V K Sood; P J Maloney; Steven M Larson; Richard C Reba
Immunoreactivity affects the biodistribution and tumor targeting of radiolabeled anti-P97 Fab fragment.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1990;31(2):202-10.
1990: S M Quadri; Chang H Paik; R C Reba; W P Hong
Optimization of biodistribution by introducing different chemical linkages between antibody and an indium-111 chelate.
Cancer treatment and research 1990;51():201-13.
1989: Chang H Paik; K Yokoyama; James C Reynolds; S M Quadri; C Y Min; S Y Shin; P J Maloney; Steven M Larson; Richard C Reba
Reduction of background activities by introduction of a diester linkage between antibody and a chelate in radioimmunodetection of tumor.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1989;30(10):1693-701.
1989: Chang H Paik; S M Quadri; Richard C Reba
Interposition of different chemical linkages between antibody and 111In-DTPA to accelerate clearance from non-target organs and blood.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1989;16(5):475-81.

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