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Krzysztof Palczewski

Research Profile

Chemicals & Drugs

Living Beings

Genes & Molecular Sequences

Amino Acid Sequences

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Anatomy

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Light

Physiology

Vision, Ocular

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Publications

TOP 3
Yaroslav Tsybovsky; Derek Taylor; Robert S Molday; Tivadar Orban; Krzysztof Palczewski
Molecular Organization and ATP-Induced Conformational Changes of ABCA4, the Photoreceptor-Specific ABC Transporter.
Krzysztof Palczewski; Philip D Kiser
Biochemistry. As good as chocolate.
Beata Jastrzebska; Krzysztof Palczewski; Philippe Ringler; Andreas Engel
The rhodopsin-transducin complex houses two distinct rhodopsin molecules.

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All Publications

2013: Yaroslav Tsybovsky; Derek Taylor; Robert S Molday; Tivadar Orban; Krzysztof Palczewski
Molecular Organization and ATP-Induced Conformational Changes of ABCA4, the Photoreceptor-Specific ABC Transporter.
Structure (London, England : 1993) 2013;21(5):854-60.
2013: Krzysztof Palczewski; Philip D Kiser
Biochemistry. As good as chocolate.
Science (New York, N.Y.) 2013;340(6132):562-3.
2013: Beata Jastrzebska; Krzysztof Palczewski; Philippe Ringler; Andreas Engel
The rhodopsin-transducin complex houses two distinct rhodopsin molecules.
Journal of structural biology 2013;182(2):164-72.
2013: Pius S Padayatti; Krzysztof Palczewski; David Salom; Wenyu Sun; Liwen Wang; Sayan Gupta; Steven R Jordan; Tivadar Orban; Mark R Chance
A Hybrid Structural Approach to Analyze Ligand Binding by the Serotonin Type 4 Receptor (5-HT4).
Molecular & cellular proteomics : MCP 2013;12(5):1259-71.
2013: Junpeng Yan; Chuanping Wang; Jinwoo Ahn; Maria Delucia; Marcin Golczak; Angela M Gronenborn; Caili Hao; Sarabpreet Kaur; Jennifer Mehrens; Krzysztof Palczewski; Jacek Skowronski
Tetramerization of SAMHD1 Is Required for Biological Activity and Inhibition of HIV Infection.
The Journal of biological chemistry 2013;288(15):10406-17.
2013: Beata Jastrzebska; Tivadar Orban; Andreas Engel; Marcin Golczak; Krzysztof Palczewski
Asymmetry of the rhodopsin dimer in complex with transducin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013;27(4):1572-84.
2013: Ning Zhang; Osamu Sawada; Andreas Engel; Christel Genoud; Beata Jastrzebska; Vladimir Kefalov; Alexander V Kolesnikov; Tadao Maeda; Debarshi Mustafi; Krzysztof Palczewski
Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization.
The Journal of clinical investigation 2013;123(1):121-37.
2013: Mei Tian; Weimin Wang; Marisa Zallocchi; Ching-Kang Chen; Dominic Cosgrove; Duane C Delimont; Krzysztof Palczewski; You-Wei Peng
Light-Induced Translocation of RGS9-1 and Gβ5L in Mouse Rod Photoreceptors.
PloS one 2013;8(3):e58832.
2013: Beata Jastrzebska; Hui Jin; Krzysztof Palczewski; David Salom; Wenyu Sun; Pengxiu Cao; Zhaoyang Feng
Expression of mammalian G protein-coupled receptors in Caenorhabditis elegans.
Methods in enzymology 2013;520():239-56.
2013: Ardeschir Vahedi-Faridi; Beata Jastrzebska; Krzysztof Palczewski; Andreas Engel
3D imaging and quantitative analysis of small solubilized membrane proteins and their complexes by transmission electron microscopy.
Journal of electron microscopy 2013;62(1):95-107.
2013: Tadao Maeda; Wendy Monk; Grazyna Palczewska; Zhiqian Dong; Songqi Gao; Hui Jin; Osamu Sawada; Deepank Utkhede; Krzysztof Palczewski
QLT091001, a 9-cis-retinal analog, is well-tolerated by retinas of mice with impaired visual cycles.
Investigative ophthalmology & visual science 2013;54(1):455-66.
2012: Xiongying Tu; Krzysztof Palczewski
Crystal structure of the globular domain of C1QTNF5: Implications for late-onset retinal macular degeneration.
Journal of structural biology 2012;180(3):439-46.
2012: Philip D Kiser; Mark R Chance; Erik R Farquhar; Wuxian Shi; Xuewu Sui; Krzysztof Palczewski
Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(41):E2747-56.
2012: Song-Qi Gao; Tadao Maeda; Kiichiro Okano; Krzysztof Palczewski
A microparticle/hydrogel combination drug-delivery system for sustained release of retinoids.
Investigative ophthalmology & visual science 2012;53(10):6314-23.
2012: Atsuko Hachiya; Karen A Kirby; Eiichi N Kodama; Zhe Li; Bruno Marchand; Eleftherios Michailidis; Shinichi Oka; Yee Tsuey Ong; Krzysztof Palczewski; Matthew M Schuckmann; Kamalendra Singh; Junko Tanuma; Xiongying Tu; Daniel T Griffin; Stefan G Sarafianos
HIV-1 reverse transcriptase (RT) polymorphism 172K suppresses the effect of clinically relevant drug resistance mutations to both nucleoside and non-nucleoside RT inhibitors.
The Journal of biological chemistry 2012;287(35):29988-99.
2012: Debarshi Mustafi; Joseph H Nadeau; Hideo Kohno; Tadao Maeda; Krzysztof Palczewski
Inflammatory priming predisposes mice to age-related retinal degeneration.
The Journal of clinical investigation 2012;122(8):2989-3001.
2012: Thomas R Sundermeier; Krzysztof Palczewski
The physiological impact of microRNA gene regulation in the retina.
Cellular and molecular life sciences : CMLS 2012;69(16):2739-50.
2012: Jaume Amengual; Marcin Golczak; Krzysztof Palczewski; Johannes Von Lintig
Lecithin:retinol acyltransferase is critical for cellular uptake of vitamin A from serum retinol-binding protein.
The Journal of biological chemistry 2012;287(29):24216-27.
2012: Marcin Golczak; Philip D Kiser; David T Lodowski; William S Blaner; Avery E Sears; Krzysztof Palczewski
Structural basis for the acyltransferase activity of lecithin:retinol acyltransferase-like proteins.
The Journal of biological chemistry 2012;287(28):23790-807.
2012: Timothy J Sexton; Marcin Golczak; Krzysztof Palczewski; Russell N Van Gelder
Melanopsin is highly resistant to light and chemical bleaching in vivo.
The Journal of biological chemistry 2012;287(25):20888-97.
2012: Tivadar Orban; Benlian Wang; Mark R Chance; Sayan Gupta; Beata Jastrzebska; Masaru Miyagi; Krzysztof Palczewski
Conformational dynamics of activation for the pentameric complex of dimeric G protein-coupled receptor and heterotrimeric G protein.
Structure (London, England : 1993) 2012;20(5):826-40.
2012: Tivadar Orban; Kristoff T Homan; Chih-Chin Huang; Beata Jastrzebska; John J G Tesmer; Krzysztof Palczewski
Substrate-induced changes in the dynamics of rhodopsin kinase (G protein-coupled receptor kinase 1).
Biochemistry 2012;51(16):3404-11.
2012: Yuanyuan Chen; Erik R Farquhar; Mark R Chance; Krzysztof Palczewski; Philip D Kiser
Insights into substrate specificity and metal activation of mammalian tetrahedral aspartyl aminopeptidase.
The Journal of biological chemistry 2012;287(16):13356-70.
2012: Kiichiro Okano; Grazyna Palczewska; Krzysztof Palczewski; Tsutomu Sakai; Johnny Tang; Hiroshi Tsuneoka; Vishal Chauhan; Yu Chen; Akiko Maeda; Tadao Maeda
Retinal cone and rod photoreceptor cells exhibit differential susceptibility to light-induced damage.
Journal of neurochemistry 2012;121(1):146-56.
2012: Pius Padayatti; Grazyna Palczewska; Krzysztof Palczewski; Wenyu Sun; David Salom
Imaging of protein crystals with two-photon microscopy.
Biochemistry 2012;51(8):1625-37.
2012: Yu Chen; Marcin Golczak; Akiko Maeda; Tadao Maeda; Kiichiro Okano; Vishal Chauhan; Krzysztof Palczewski
Mechanism of all-trans-retinal toxicity with implications for stargardt disease and age-related macular degeneration.
The Journal of biological chemistry 2012;287(7):5059-69.
2012: Akiko Maeda; Tadao Maeda; Kiichiro Okano; Grazyna Palczewska; Yu Chen; Marcin Golczak; William Harte; Kaede Ishikawa; Hideo Kohno; Satomi Shiose; Krzysztof Palczewski
Primary amines protect against retinal degeneration in mouse models of retinopathies.
Nature chemical biology 2012;8(2):170-8.
2012: David Salom; Wenyu Sun; Pengxiu Cao; Zhaoyang Feng; Beata Jastrzebska; Hui Jin; Kristopher Kramp; Krzysztof Palczewski
Heterologous expression of functional G-protein-coupled receptors in Caenorhabditis elegans.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(2):492-502.
2012: Pengxiu Cao; Beata Jastrzebska; Hui Jin; Kristopher Kramp; Krzysztof Palczewski; David Salom; Wenyu Sun; Maohua Zheng; Zhaoyang Feng
Light-sensitive coupling of rhodopsin and melanopsin to G(i/o) and G(q) signal transduction in Caenorhabditis elegans.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(2):480-91.
2012: Krzysztof Palczewski
Chemistry and biology of vision.
The Journal of biological chemistry 2012;287(3):1612-9.
2012: Krzysztof Palczewski
Thematic minireview series on focus on vision.
The Journal of biological chemistry 2012;287(3):1610-1.
2012: Dorota Latek; Anna Modzelewska; Krzysztof Palczewski; Bartosz Trzaskowski; Slawomir Filipek
G protein-coupled receptors--recent advances.
Acta biochimica Polonica 2012;59(4):515-29.
2011: John A Salon; David T Lodowski; Krzysztof Palczewski
The significance of G protein-coupled receptor crystallography for drug discovery.
Pharmacological reviews 2011;63(4):901-37.
2011: Beata Jastrzebska; David T Lodowski; Vera Moiseenkova-Bell; Shirley A Müller; Krzysztof Palczewski; Philippe Ringler; Marcin Golczak; Andreas Engel
Rhodopsin-transducin heteropentamer: three-dimensional structure and biochemical characterization.
Journal of structural biology 2011;176(3):387-94.
2011: Bo Y Baker; Krzysztof Palczewski
Detergents stabilize the conformation of phosphodiesterase 6.
Biochemistry 2011;50(44):9520-31.
2011: Tadao Maeda; Krzysztof Palczewski; Lindsay Perusek; Jaume Amengual; Darwin Babino; Johannes Von Lintig
Dietary 9-cis-β,β-carotene fails to rescue vision in mouse models of leber congenital amaurosis.
Molecular pharmacology 2011;80(5):943-52.
2011: Qubo Zhu; Wenyu Sun; Ning Zhang; Yu Chen; Tadao Maeda; Kiichiro Okano; Krzysztof Palczewski
Sponge transgenic mouse model reveals important roles for the microRNA-183 (miR-183)/96/182 cluster in postmitotic photoreceptors of the retina.
The Journal of biological chemistry 2011;286(36):31749-60.
2011: Debarshi Mustafi; Kiichiro Okano; Alejandro J Roman; Alexander Sumaroka; Mark D Adams; Artur V Cideciyan; Andreas Engel; Christel Genoud; Samuel G Jacobson; Brian M Kevany; Krzysztof Palczewski
Defective photoreceptor phagocytosis in a mouse model of enhanced S-cone syndrome causes progressive retinal degeneration.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(9):3157-76.
2011: Yaroslav Tsybovsky; Benlian Wang; Robert S Molday; Faraz Quazi; Krzysztof Palczewski
Posttranslational modifications of the photoreceptor-specific ABC transporter ABCA4.
Biochemistry 2011;50(32):6855-66.
2011: Beata Jastrzebska; Aleksander Debinski; Slawomir Filipek; Krzysztof Palczewski
Role of membrane integrity on G protein-coupled receptors: Rhodopsin stability and function.
Progress in lipid research 2011;50(3):267-77.
2011: Igor V Peshenko; Andrey B Savchenko; Wolfgang Baehr; Sukanya Karan; Elena V Olshevskaya; Krzysztof Palczewski; Alexander M Dizhoor
Enzymatic properties and regulation of the native isozymes of retinal membrane guanylyl cyclase (RetGC) from mouse photoreceptors.
Biochemistry 2011;50(25):5590-600.
2011: Beata Jastrzebska; Krzysztof Palczewski; Marcin Golczak
Role of bulk water in hydrolysis of the rhodopsin chromophore.
The Journal of biological chemistry 2011;286(21):18930-7.
2011: Debarshi Mustafi; Amir Avishai; Nanthawan Avishai; Andreas Engel; Arthur Heuer; Krzysztof Palczewski
Serial sectioning for examination of photoreceptor cell architecture by focused ion beam technology.
Journal of neuroscience methods 2011;198(1):70-6.
2011: Tivadar Orban; Grazyna Palczewska; Krzysztof Palczewski
Retinyl ester storage particles (retinosomes) from the retinal pigmented epithelium resemble lipid droplets in other tissues.
The Journal of biological chemistry 2011;286(19):17248-58.
2011: Grzegorz Bereta; Krzysztof Palczewski
Heterogeneous N-terminal acylation of retinal proteins results from the retina's unusual lipid metabolism.
Biochemistry 2011;50(18):3764-76.
2011: Satomi Shiose; Yu Chen; Kiichiro Okano; Sanhita Roy; Hideo Kohno; Johnny Tang; Eric Pearlman; Tadao Maeda; Krzysztof Palczewski; Akiko Maeda
Toll-like receptor 3 is required for development of retinopathy caused by impaired all-trans-retinal clearance in mice.
The Journal of biological chemistry 2011;286(17):15543-55.
2011: Sanae Sakami; Tadao Maeda; Grzegorz Bereta; Kiichiro Okano; Marcin Golczak; Alexander Sumaroka; Alejandro J Roman; Artur V Cideciyan; Samuel G Jacobson; Krzysztof Palczewski
Probing mechanisms of photoreceptor degeneration in a new mouse model of the common form of autosomal dominant retinitis pigmentosa due to P23H opsin mutations.
The Journal of biological chemistry 2011;286(12):10551-67.
2011: Chih-Chin Huang; Tivadar Orban; Beata Jastrzebska; Krzysztof Palczewski; John J G Tesmer
Activation of G protein-coupled receptor kinase 1 involves interactions between its N-terminal region and its kinase domain.
Biochemistry 2011;50(11):1940-9.
2011: Jaume Amengual; Glenn P Lobo; Marcin Golczak; Hua Nan M Li; Tatyana Klimova; Charles L Hoppel; Adrian Wyss; Krzysztof Palczewski; Johannes Von Lintig
A mitochondrial enzyme degrades carotenoids and protects against oxidative stress.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(3):948-59.
2011: Natalia Mast; Andrew J Annalora; David T Lodowski; Krzysztof Palczewski; C David Stout; Irina A Pikuleva
Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1.
The Journal of biological chemistry 2011;286(7):5607-13.
2011: Krzysztof Palczewski
Focus on vision: 3 decades of remarkable contributions to biology and medicine.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(2):439-43.
2011: Hui Li; Krzysztof Palczewski; Wolfgang Baehr; Margaret Clagett-Dame
Vitamin A deficiency results in meiotic failure and accumulation of undifferentiated spermatogonia in prepubertal mouse testis.
Biology of reproduction 2011;84(2):336-41.
2010: Grazyna Palczewska; Tadao Maeda; Yoshikazu Imanishi; Wenyu Sun; Yu Chen; David R Williams; David W Piston; Akiko Maeda; Krzysztof Palczewski
Noninvasive multiphoton fluorescence microscopy resolves retinol and retinal condensation products in mouse eyes.
Nature medicine 2010;16(12):1444-9.
2010: Jingwei Huang; Zan Xu; Die Wang; Craig M Ogata; Krzysztof Palczewski; Xavier Lee; N Martin Young
Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses.
Glycobiology 2010;20(12):1643-53.
2010: David T Lodowski; Krzysztof Palczewski; Masaru Miyagi
Conformational changes in the g protein-coupled receptor rhodopsin revealed by histidine hydrogen-deuterium exchange.
Biochemistry 2010;49(44):9425-7.
2010: Krzysztof Palczewski
Blind dogs that can see: pharmacological treatment of Leber congenital amaurosis caused by a defective visual cycle.
Archives of ophthalmology 2010;128(11):1483-5.
2010: Krzysztof Palczewski
Oligomeric forms of G protein-coupled receptors (GPCRs).
Trends in biochemical sciences 2010;35(11):595-600.
2010: Marcin Golczak; Krzysztof Palczewski
An acyl-covalent enzyme intermediate of lecithin:retinol acyltransferase.
The Journal of biological chemistry 2010;285(38):29217-22.
2010: Lakshmi Padmavathi Pulagam; Krzysztof Palczewski
Electrostatic compensation restores trafficking of the autosomal recessive retinitis pigmentosa E150K opsin mutant to the plasma membrane.
The Journal of biological chemistry 2010;285(38):29446-56.
2010: Glenn P Lobo; Jaume Amengual; Hua Nan M Li; Marcin Golczak; M Luisa Bonet; Krzysztof Palczewski; Johannes Von Lintig
Beta,beta-carotene decreases peroxisome proliferator receptor gamma activity and reduces lipid storage capacity of adipocytes in a beta,beta-carotene oxygenase 1-dependent manner.
The Journal of biological chemistry 2010;285(36):27891-9.
2010: Philip D Kiser; Krzysztof Palczewski
Membrane-binding and enzymatic properties of RPE65.
Progress in retinal and eye research 2010;29(5):428-42.
2010: Anna Goc; Mohamed Chami; David T Lodowski; Patrick Bosshart; Vera Moiseenkova-Bell; Wolfgang Baehr; Andreas Engel; Krzysztof Palczewski
Structural characterization of the rod cGMP phosphodiesterase 6.
Journal of molecular biology 2010;401(3):363-73.
2010: George Khelashvili; Kevin Dorff; Jufang Shan; Marta Camacho-Artacho; Lucy Skrabanek; Bas Vroling; Michel Bouvier; Lakshmi A Devi; Susan R George; Jonathan A Javitch; Martin J Lohse; Graeme Milligan; Richard Neubig; Krzysztof Palczewski; Marc Parmentier; Jean-Philippe Pin; Gert Vriend; Fabien Campagne; Marta Filizola
GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base.
Bioinformatics (Oxford, England) 2010;26(14):1804-5.
2010: Johannes Von Lintig; Philip D Kiser; Marcin Golczak; Krzysztof Palczewski
The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision.
Trends in biochemical sciences 2010;35(7):400-10.
2010: Krzysztof Palczewski
Retinoids for treatment of retinal diseases.
Trends in pharmacological sciences 2010;31(6):284-95.
2010: Glenn P Lobo; Susanne Hessel; Anne Eichinger; Noa Noy; Alexander R Moise; Adrian Wyss; Krzysztof Palczewski; Johannes Von Lintig
ISX is a retinoic acid-sensitive gatekeeper that controls intestinal beta,beta-carotene absorption and vitamin A production.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(6):1656-66.
2010: Beata Jastrzebska; Yaroslav Tsybovsky; Krzysztof Palczewski
Complexes between photoactivated rhodopsin and transducin: progress and questions.
The Biochemical journal 2010;428(1):1-10.
2010: Akiko Maeda; Kiichiro Okano; Paul S-H Park; Janis Lem; Rosalie K Crouch; Tadao Maeda; Krzysztof Palczewski
Palmitoylation stabilizes unliganded rod opsin.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(18):8428-33.
2010: Sheila M O'Byrne; Yuko Kako; Richard J Deckelbaum; Inge H Hansen; Krzysztof Palczewski; Ira J Goldberg; William S Blaner
Multiple pathways ensure retinoid delivery to milk: studies in genetically modified mice.
American journal of physiology. Endocrinology and metabolism 2010;298(4):E862-70.
2010: Alexander R Moise; Glenn P Lobo; Bernadette Erokwu; David L Wilson; David Peck; Susana Alvarez; Marta Domínguez; Rosana Alvarez; Chris A Flask; Angel R de Lera; Johannes Von Lintig; Krzysztof Palczewski
Increased adiposity in the retinol saturase-knockout mouse.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(4):1261-70.
2010: Marcin Golczak; Philip D Kiser; David T Lodowski; Akiko Maeda; Krzysztof Palczewski
Importance of membrane structural integrity for RPE65 retinoid isomerization activity.
The Journal of biological chemistry 2010;285(13):9667-82.
2010: Tivadar Orban; Sayan Gupta; Krzysztof Palczewski; Mark R Chance
Visualizing water molecules in transmembrane proteins using radiolytic labeling methods.
Biochemistry 2010;49(5):827-34.
2010: Brian M Kevany; Krzysztof Palczewski
Phagocytosis of retinal rod and cone photoreceptors.
Physiology (Bethesda, Md.) 2010;25(1):8-15.
2010: Grzegorz Bereta; Benlian Wang; Philip D Kiser; Wolfgang Baehr; Geeng-Fu Jang; Krzysztof Palczewski
A functional kinase homology domain is essential for the activity of photoreceptor guanylate cyclase 1.
The Journal of biological chemistry 2010;285(3):1899-908.
2010: Tivadar Orban; Grzegorz Bereta; Masaru Miyagi; Benlian Wang; Mark R Chance; Marcelo Carlos Sousa; Krzysztof Palczewski
Conformational changes in guanylate cyclase-activating protein 1 induced by Ca2+ and N-terminal fatty acid acylation.
Structure (London, England : 1993) 2010;18(1):116-26.
2010: Jennifer J Hunter; Benjamin Masella; Alfredo Dubra; Robin Sharma; Lu Yin; William H Merigan; Grazyna Palczewska; Krzysztof Palczewski; David R Williams
Images of photoreceptors in living primate eyes using adaptive optics two-photon ophthalmoscopy.
Biomedical optics express 2010;2(1):139-48.
2010: Yaroslav Tsybovsky; Robert S Molday; Krzysztof Palczewski
The ATP-binding cassette transporter ABCA4: structural and functional properties and role in retinal disease.
Advances in experimental medicine and biology 2010;703():105-25.
2010: Yoshikazu Imanishi; Krzysztof Palczewski
Visualization of retinoid storage and trafficking by two-photon microscopy.
Methods in molecular biology (Clifton, N.J.) 2010;652():247-61.
2010: Marcin Golczak; Grzegorz Bereta; Akiko Maeda; Krzysztof Palczewski
Molecular biology and analytical chemistry methods used to probe the retinoid cycle.
Methods in molecular biology (Clifton, N.J.) 2010;652():229-45.
2010: Pengxiu Cao; Yiyuan Yuan; Elizabeth A Pehek; Alex R Moise; Ying Huang; Krzysztof Palczewski; Zhaoyang Feng
Alpha-synuclein disrupted dopamine homeostasis leads to dopaminergic neuron degeneration in Caenorhabditis elegans.
PloS one 2010;5(2):e9312.
2009: Alexander R Moise; Susana Alvarez; Marta Domínguez; Rosana Alvarez; Marcin Golczak; Glenn P Lobo; Johannes Von Lintig; Angel R de Lera; Krzysztof Palczewski
Activation of retinoic acid receptors by dihydroretinoids.
Molecular pharmacology 2009;76(6):1228-37.
2009: Akiko Maeda; Marcin Golczak; Tadao Maeda; Krzysztof Palczewski
Limited roles of Rdh8, Rdh12, and Abca4 in all-trans-retinal clearance in mouse retina.
Investigative ophthalmology & visual science 2009;50(11):5435-43.
2009: Philip D Kiser; Marcin Golczak; David T Lodowski; Mark R Chance; Krzysztof Palczewski
Crystal structure of native RPE65, the retinoid isomerase of the visual cycle.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(41):17325-30.
2009: Philip D Kiser; George H Lorimer; Krzysztof Palczewski
Use of thallium to identify monovalent cation binding sites in GroEL.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 10):967-71.
2009: Tadao Maeda; Akiko Maeda; Melissa Matosky; Kiichiro Okano; Satsumi Roos; Johnny Tang; Krzysztof Palczewski
Evaluation of potential therapies for a mouse model of human age-related macular degeneration caused by delayed all-trans-retinal clearance.
Investigative ophthalmology & visual science 2009;50(10):4917-25.
2009: Tadao Maeda; Akiko Maeda; Gemma Casadesus Smith; Krzysztof Palczewski; Philippe Margaron
Evaluation of 9-cis-retinyl acetate therapy in Rpe65-/- mice.
Investigative ophthalmology & visual science 2009;50(9):4368-78.
2009: Thomas E Angel; Sayan Gupta; Beata Jastrzebska; Krzysztof Palczewski; Mark R Chance
Structural waters define a functional channel mediating activation of the GPCR, rhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(34):14367-72.
2009: Ruishuang Geng; Scott F Geller; Toshinori Hayashi; Catherine A Ray; Thomas A Reh; Olivia Bermingham-McDonogh; Sherri M Jones; Charles G Wright; Sami Melki; Yoshikazu Imanishi; Krzysztof Palczewski; Kumar N Alagramam; John G Flannery
Usher syndrome IIIA gene clarin-1 is essential for hair cell function and associated neural activation.
Human molecular genetics 2009;18(15):2748-60.
2009: Guilian Tian; Yun Zhou; Dagmar Hajkova; Masaru Miyagi; Astra Dinculescu; William W Hauswirth; Krzysztof Palczewski; Ruishuang Geng; Kumar N Alagramam; Juha Isosomppi; Eeva-Marja Sankila; John G Flannery; Yoshikazu Imanishi
Clarin-1, encoded by the Usher Syndrome III causative gene, forms a membranous microdomain: possible role of clarin-1 in organizing the actin cytoskeleton.
The Journal of biological chemistry 2009;284(28):18980-93.
2009: Debarshi Mustafi; Andreas H Engel; Krzysztof Palczewski
Structure of cone photoreceptors.
Progress in retinal and eye research 2009;28(4):289-302.
2009: Beata Jastrzebska; Anna Goc; Marcin Golczak; Krzysztof Palczewski
Phospholipids are needed for the proper formation, stability, and function of the photoactivated rhodopsin-transducin complex.
Biochemistry 2009;48(23):5159-70.
2009: Tadao Maeda; Artur Vahe Cideciyan; Akiko Maeda; Marcin Golczak; Tomas S Aleman; Samuel G Jacobson; Krzysztof Palczewski
Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate.
Human molecular genetics 2009;18(12):2277-87.
2009: Wolfgang Baehr; Krzysztof Palczewski
Focus on molecules: guanylate cyclase-activating proteins (GCAPs).
Experimental eye research 2009;89(1):2-3.
2009: Akiko Maeda; Tadao Maeda; Marcin Golczak; Steven Chou; Amar Desai; Charles L Hoppel; Shigemi Matsuyama; Krzysztof Palczewski
Involvement of all-trans-retinal in acute light-induced retinopathy of mice.
The Journal of biological chemistry 2009;284(22):15173-83.
2009: Thomas E Angel; Mark R Chance; Krzysztof Palczewski
Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(21):8555-60.
2009: Paul S-H Park; K Tanuj Sapra; Beata Jastrzebska; Tadao Maeda; Akiko Maeda; Wojciech Pulawski; Masahiro Kono; Janis Lem; Rosalie K Crouch; Slawomir Filipek; Daniel J Müller; Krzysztof Palczewski
Modulation of molecular interactions and function by rhodopsin palmitylation.
Biochemistry 2009;48(20):4294-304.
2009: David T Lodowski; Krzysztof Palczewski
Chemokine receptors and other G protein-coupled receptors.
Current opinion in HIV and AIDS 2009;4(2):88-95.
2009: David T Lodowski; Thomas E Angel; Krzysztof Palczewski
Comparative analysis of GPCR crystal structures.
Photochemistry and photobiology 2009;85(2):425-30.
2009: Artur Vahe Cideciyan; Malgorzata Swider; Tomas S Aleman; Yaroslav Tsybovsky; Sharon B Schwartz; Elizabeth A M Windsor; Alejandro J Roman; Alexander Sumaroka; Janet D Steinberg; Samuel G Jacobson; Edwin M Stone; Krzysztof Palczewski
ABCA4 disease progression and a proposed strategy for gene therapy.
Human molecular genetics 2009;18(5):931-41.
2009: Beata Jastrzebska; Marcin Golczak; Dimitrios Fotiadis; Andreas Engel; Krzysztof Palczewski
Isolation and functional characterization of a stable complex between photoactivated rhodopsin and the G protein, transducin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(2):371-81.
2009: Congmin Li; Jenny Chan; Francoise Haeseleer; Katsuhiko Mikoshiba; Krzysztof Palczewski; Mitsuhiko Ikura; James B Ames
Structural insights into Ca2+-dependent regulation of inositol 1,4,5-trisphosphate receptors by CaBP1.
The Journal of biological chemistry 2009;284(4):2472-81.
2009: Tadao Maeda; Akiko Maeda; Patrick Leahy; David A Saperstein; Krzysztof Palczewski
Effects of long-term administration of 9-cis-retinyl acetate on visual function in mice.
Investigative ophthalmology & visual science 2009;50(1):322-33.
2008: David Salom; Nan Wu; Wenyu Sun; Zhiqian Dong; Krzysztof Palczewski; Steven Jordan; John A Salon
Heterologous expression and purification of the serotonin type 4 receptor from transgenic mouse retina.
Biochemistry 2008;47(50):13296-307.
2008: Anna Goc; Thomas E Angel; Beata Jastrzebska; Benlian Wang; Patrick Wintrode; Krzysztof Palczewski
Different properties of the native and reconstituted heterotrimeric G protein transducin.
Biochemistry 2008;47(47):12409-19.
2008: Li Jiang; Dianna Wheaton; Grzegorz Bereta; Kang Zhang; Krzysztof Palczewski; David G Birch; Wolfgang Baehr
A novel GCAP1(N104K) mutation in EF-hand 3 (EF3) linked to autosomal dominant cone dystrophy.
Vision research 2008;48(23-24):2425-32.
2008: Akiko Maeda; Tadao Maeda; Marcin Golczak; Krzysztof Palczewski
Retinopathy in mice induced by disrupted all-trans-retinal clearance.
The Journal of biological chemistry 2008;283(39):26684-93.
2008: Grzegorz Bereta; Philip D Kiser; Marcin Golczak; Wenyu Sun; Elise Heon; David A Saperstein; Krzysztof Palczewski
Impact of retinal disease-associated RPE65 mutations on retinoid isomerization.
Biochemistry 2008;47(37):9856-65.
2008: Yoshikazu Imanishi; Wenyu Sun; Tadao Maeda; Akiko Maeda; Krzysztof Palczewski
Retinyl ester homeostasis in the adipose differentiation-related protein-deficient retina.
The Journal of biological chemistry 2008;283(36):25091-102.
2008: Ricardo Stephen; Sławomir Filipek; Krzysztof Palczewski; Marcelo C Sousa
Ca2+ -dependent regulation of phototransduction.
Photochemistry and photobiology 2008;84(4):903-10.
2008: Nuttaporn Wongsiriroj; Roseann Piantedosi; Krzysztof Palczewski; Ira J Goldberg; Thomas P Johnston; Ellen Li; William S Blaner
The molecular basis of retinoid absorption: a genetic dissection.
The Journal of biological chemistry 2008;283(20):13510-9.
2008: Puja Singh; Benlian Wang; Tadao Maeda; Krzysztof Palczewski; John J G Tesmer
Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation.
The Journal of biological chemistry 2008;283(20):14053-62.
2008: Marcin Golczak; Akiko Maeda; Grzegorz Bereta; Tadao Maeda; Philip D Kiser; Silke Hunzelmann; Johannes Von Lintig; William S Blaner; Krzysztof Palczewski
Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina.
The Journal of biological chemistry 2008;283(15):9543-54.
2008: Houbin Zhang; Jie Fan; Sha Li; Sukanya Karan; Baerbel Rohrer; Krzysztof Palczewski; Jeanne M Frederick; Rosalie K Crouch; Wolfgang Baehr
Trafficking of membrane-associated proteins to cone photoreceptor outer segments requires the chromophore 11-cis-retinal.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(15):4008-14.
2008: Daniel J Müller; Nan Wu; Krzysztof Palczewski
Vertebrate membrane proteins: structure, function, and insights from biophysical approaches.
Pharmacological reviews 2008;60(1):43-78.
2008: Andrea Isken; Marcin Golczak; Vitus Oberhauser; Silke Hunzelmann; Wolfgang Driever; Yoshikazu Imanishi; Krzysztof Palczewski; Johannes Von Lintig
RBP4 disrupts vitamin A uptake homeostasis in a STRA6-deficient animal model for Matthew-Wood syndrome.
Cell metabolism 2008;7(3):258-68.
2008: Youn-Kyung Kim; Lesley Wassef; Leora Hamberger; Roseann Piantedosi; Krzysztof Palczewski; William S Blaner; Loredana Quadro
Retinyl ester formation by lecithin: retinol acyltransferase is a key regulator of retinoid homeostasis in mouse embryogenesis.
The Journal of biological chemistry 2008;283(9):5611-21.
2008: K Tanuj Sapra; Paul S-H Park; Krzysztof Palczewski; Daniel Müller
Mechanical properties of bovine rhodopsin and bacteriorhodopsin: possible roles in folding and function.
Langmuir : the ACS journal of surfaces and colloids 2008;24(4):1330-7.
2008: Matthew R Whorton; Beata Jastrzebska; Paul S-H Park; Dimitrios Fotiadis; Andreas Engel; Krzysztof Palczewski; Roger K Sunahara
Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer.
The Journal of biological chemistry 2008;283(7):4387-94.
2008: Alexander R Moise; Marta Domínguez; Susana Alvarez; Rosana Alvarez; Michael Schupp; Ana G Cristancho; Philip D Kiser; Angel R de Lera; Mitchell Lazar; Krzysztof Palczewski
Stereospecificity of retinol saturase: absolute configuration, synthesis, and biological evaluation of dihydroretinoids.
Journal of the American Chemical Society 2008;130(4):1154-5.
2008: Paul S-H Park; David T Lodowski; Krzysztof Palczewski
Activation of G protein-coupled receptors: beyond two-state models and tertiary conformational changes.
Annual review of pharmacology and toxicology 2008;48():107-41.
2007: Akiko Maeda; Tadao Maeda; Wenyu Sun; Houbin Zhang; Wolfgang Baehr; Krzysztof Palczewski
Redundant and unique roles of retinol dehydrogenases in the mouse retina.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(49):19565-70.
2007: Ricardo Stephen; Grzegorz Bereta; Marcin Golczak; Krzysztof Palczewski; Marcelo C Sousa
Stabilizing function for myristoyl group revealed by the crystal structure of a neuronal calcium sensor, guanylate cyclase-activating protein 1.
Structure (London, England : 1993) 2007;15(11):1392-402.
2007: Helia B Schonthaler; Johanna M Lampert; Andrea Isken; Oliver Rinner; Andreas Mader; Matthias Gesemann; Vitus Oberhauser; Marcin Golczak; Oliver Biehlmaier; Krzysztof Palczewski; Stephan Neuhauss; Johannes Von Lintig
Evidence for RPE65-independent vision in the cone-dominated zebrafish retina.
The European journal of neuroscience 2007;26(7):1940-9.
2007: Samuel G Jacobson; Tomas S Aleman; Artur Vahe Cideciyan; Elise Heon; Marcin Golczak; William A Beltran; Alexander Sumaroka; Sharon B Schwartz; Alejandro J Roman; Elizabeth A M Windsor; James M Wilson; Gustavo D Aguirre; Edwin M Stone; Krzysztof Palczewski
Human cone photoreceptor dependence on RPE65 isomerase.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(38):15123-8.
2007: David T Lodowski; David Salom; Isolde Le Trong; David C Teller; Juan A Ballesteros; Krzysztof Palczewski; Ronald E Stenkamp
Reprint of "Crystal packing analysis of Rhodopsin crystals" [J. Struct. Biol. 158 (2007) 455-462].
Journal of structural biology 2007;159(2):253-60.
2007: Ning Li; David Salom; Li Zhang; Tim Harris; Juan A Ballesteros; Marcin Golczak; Beata Jastrzebska; Krzysztof Palczewski; Carole Kurahara; Todd Juan; Steven Jordan; John A Salon
Heterologous expression of the adenosine A1 receptor in transgenic mouse retina.
Biochemistry 2007;46(28):8350-9.
2007: Wenyu Sun; Christina Gerth; Akiko Maeda; David T Lodowski; Lauren Van Der Kraak; David A Saperstein; Elise Héon; Krzysztof Palczewski
Novel RDH12 mutations associated with Leber congenital amaurosis and cone-rod dystrophy: biochemical and clinical evaluations.
Vision research 2007;47(15):2055-66.
2007: Stephan Nickell; Paul S-H Park; Wolfgang Baumeister; Krzysztof Palczewski
Three-dimensional architecture of murine rod outer segments determined by cryoelectron tomography.
The Journal of cell biology 2007;177(5):917-25.
2007: Philip D Kiser; David T Lodowski; Krzysztof Palczewski
Purification, crystallization and structure determination of native GroEL from Escherichia coli lacking bound potassium ions.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 6):457-61.
2007: David T Lodowski; David Salom; Isolde Le Trong; David C Teller; Juan A Ballesteros; Krzysztof Palczewski; Ronald E Stenkamp
Crystal packing analysis of Rhodopsin crystals.
Journal of structural biology 2007;158(3):455-62.
2007: Alexander R Moise; Noa Noy; Krzysztof Palczewski; William S Blaner
Delivery of retinoid-based therapies to target tissues.
Biochemistry 2007;46(15):4449-58.
2007: Paul S-H Park; K Tanuj Sapra; Michał Koliński; Slawomir Filipek; Krzysztof Palczewski; Daniel Müller
Stabilizing effect of Zn2+ in native bovine rhodopsin.
The Journal of biological chemistry 2007;282(15):11377-85.
2007: Kevin D Ridge; Krzysztof Palczewski
Visual rhodopsin sees the light: structure and mechanism of G protein signaling.
The Journal of biological chemistry 2007;282(13):9297-301.
2007: Wolfgang Baehr; Sukanya Karan; Tadao Maeda; Donggen Luo; Sha Li; J Darin Bronson; Carl B Watt; King-Wai Yau; Jeanne M Frederick; Krzysztof Palczewski
The function of guanylate cyclase 1 and guanylate cyclase 2 in rod and cone photoreceptors.
The Journal of biological chemistry 2007;282(12):8837-47.
2007: Jean-Philippe Pin; Richard Neubig; Michel Bouvier; Lakshmi Devi; Marta Filizola; Jonathan A Javitch; Martin J Lohse; Graeme Milligan; Krzysztof Palczewski; Marc Parmentier; Michael Spedding
International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers.
Pharmacological reviews 2007;59(1):5-13.
2007: Alexander R Moise; Andrea Isken; Marta Domínguez; Angel R de Lera; Johannes Von Lintig; Krzysztof Palczewski
Specificity of zebrafish retinol saturase: formation of all-trans-13,14-dihydroretinol and all-trans-7,8- dihydroretinol.
Biochemistry 2007;46(7):1811-20.
2007: Alexander R Moise; Marcin Golczak; Yoshikazu Imanishi; Krzysztof Palczewski
Topology and membrane association of lecithin: retinol acyltransferase.
The Journal of biological chemistry 2007;282(3):2081-90.
2007: Andrea Isken; Jochen Holzschuh; Johanna M Lampert; Lara Fischer; Vitus Oberhauser; Krzysztof Palczewski; Johannes Von Lintig
Sequestration of retinyl esters is essential for retinoid signaling in the zebrafish embryo.
The Journal of biological chemistry 2007;282(2):1144-51.
2007: Wolfgang Baehr; Krzysztof Palczewski
Guanylate cyclase-activating proteins and retina disease.
Sub-cellular biochemistry 2007;45():71-91.
2007: Lucy Skrabanek; Marta Murcia; Michel Bouvier; Lakshmi Devi; Susan R George; Martin J Lohse; Graeme Milligan; Richard Neubig; Krzysztof Palczewski; Marc Parmentier; Jean-Philippe Pin; Gert Vriend; Jonathan A Javitch; Fabien Campagne; Marta Filizola
Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base.
BMC bioinformatics 2007;8():177.
2007: Gabriel H Travis; Marcin Golczak; Alexander R Moise; Krzysztof Palczewski
Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents.
Annual review of pharmacology and toxicology 2007;47():469-512.
2006: Akiko Maeda; Tadao Maeda; Yoshikazu Imanishi; Wenyu Sun; Beata Jastrzebska; Denise A Hatala; Huub J Winkens; Klaus Peter Hofmann; Jacques J M Janssen; Wolfgang Baehr; Carola A G G Driessen; Krzysztof Palczewski
Retinol dehydrogenase (RDH12) protects photoreceptors from light-induced degeneration in mice.
The Journal of biological chemistry 2006;281(49):37697-704.
2006: Krzysztof Palczewski; Klaus Peter Hofmann; Wolfgang Baehr
Rhodopsin--advances and perspectives.
Vision research 2006;46(27):4425-6.
2006: David Salom; Isolde Le Trong; Ehmke Pohl; Juan A Ballesteros; Ronald E Stenkamp; Krzysztof Palczewski; David T Lodowski
Improvements in G protein-coupled receptor purification yield light stable rhodopsin crystals.
Journal of structural biology 2006;156(3):497-504.
2006: Marta Domínguez; Rosana Alvarez; Martín Pérez; Krzysztof Palczewski; Angel R de Lera
The role of the 11-cis-retinal ring methyl substituents in visual pigment formation.
Chembiochem : a European journal of chemical biology 2006;7(11):1815-25.
2006: David Salom; David T Lodowski; Ronald E Stenkamp; Isolde Le Trong; Marcin Golczak; Beata Jastrzebska; Tim Harris; Juan A Ballesteros; Krzysztof Palczewski
Crystal structure of a photoactivated deprotonated intermediate of rhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(44):16123-8.
2006: Akiko Maeda; Tadao Maeda; Krzysztof Palczewski
Improvement in rod and cone function in mouse model of Fundus albipunctatus after pharmacologic treatment with 9-cis-retinal.
Investigative ophthalmology & visual science 2006;47(10):4540-6.
2006: Akiko Maeda; Tadao Maeda; Marcin Golczak; Yoshikazu Imanishi; Patrick Leahy; Ryo Kubota; Krzysztof Palczewski
Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice.
Molecular pharmacology 2006;70(4):1220-9.
2006: Shannon E Haire; Jijing Pang; Sanford L Boye; Izabel Sokal; Cheryl M Craft; Krzysztof Palczewski; William W Hauswirth; Susan L Semple-Rowland
Light-driven cone arrestin translocation in cones of postnatal guanylate cyclase-1 knockout mouse retina treated with AAV-GC1.
Investigative ophthalmology & visual science 2006;47(9):3745-53.
2006: Li Zhu; Yoshikazu Imanishi; Slawomir Filipek; Andrei Alekseev; Beata Jastrzebska; Wenyu Sun; David A Saperstein; Krzysztof Palczewski
Autosomal recessive retinitis pigmentosa and E150K mutation in the opsin gene.
The Journal of biological chemistry 2006;281(31):22289-98.
2006: Daniel C Tu; Leah A Owens; Lauren Anderson; Marcin Golczak; Susan E Doyle; Maureen McCall; Michael Menaker; Krzysztof Palczewski; Russell N Van Gelder
Inner retinal photoreception independent of the visual retinoid cycle.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(27):10426-31.
2006: Ricardo Stephen; Krzysztof Palczewski; Marcelo C Sousa
The crystal structure of GCAP3 suggests molecular mechanism of GCAP-linked cone dystrophies.
Journal of molecular biology 2006;359(2):266-75.
2006: Melissa L Williams; Jason E Coleman; Shannon E Haire; Tomas S Aleman; Artur Vahe Cideciyan; Izabel Sokal; Krzysztof Palczewski; Samuel G Jacobson; Susan L Semple-Rowland
Lentiviral expression of retinal guanylate cyclase-1 (RetGC1) restores vision in an avian model of childhood blindness.
PLoS medicine 2006;3(6):e201.
2006: Beata Jastrzebska; Dimitrios Fotiadis; Geeng-Fu Jang; Ronald E Stenkamp; Andreas Engel; Krzysztof Palczewski
Functional and structural characterization of rhodopsin oligomers.
The Journal of biological chemistry 2006;281(17):11917-22.
2006: K Tanuj Sapra; Paul S-H Park; Slawomir Filipek; Andreas Engel; Daniel J Müller; Krzysztof Palczewski
Detecting molecular interactions that stabilize native bovine rhodopsin.
Journal of molecular biology 2006;358(1):255-69.
2006: Akiko Maeda; Tadao Maeda; Yoshikazu Imanishi; Marcin Golczak; Alexander R Moise; Krzysztof Palczewski
Aberrant metabolites in mouse models of congenital blinding diseases: formation and storage of retinyl esters.
Biochemistry 2006;45(13):4210-9.
2006: Dimitrios Fotiadis; Beata Jastrzebska; Ansgar Philippsen; Daniel J Müller; Krzysztof Palczewski; Andreas Engel
Structure of the rhodopsin dimer: a working model for G-protein-coupled receptors.
Current opinion in structural biology 2006;16(2):252-9.
2006: Steven E Mansoor; Krzysztof Palczewski; David L Farrens
Rhodopsin self-associates in asolectin liposomes.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3060-5.
2006: Anna Modzelewska; Slawomir Filipek; Krzysztof Palczewski; Paul S-H Park
Arrestin interaction with rhodopsin: conceptual models.
Cell biochemistry and biophysics 2006;46(1):1-15.
2006: Krzysztof Palczewski
G protein-coupled receptor rhodopsin.
Annual review of biochemistry 2006;75():743-67.
2005: Marcin Golczak; Yoshikazu Imanishi; Vladimir Kuksa; Tadao Maeda; Ryo Kubota; Krzysztof Palczewski
Lecithin:retinol acyltransferase is responsible for amidation of retinylamine, a potent inhibitor of the retinoid cycle.
The Journal of biological chemistry 2005;280(51):42263-73.
2005: Gregory M Acland; Gustavo D Aguirre; Jean Bennett; Tomas S Aleman; Artur Vahe Cideciyan; Jeannette Bennicelli; Nadine S Dejneka; Susan E Pearce-Kelling; Albert M Maguire; Krzysztof Palczewski; William W Hauswirth; Samuel G Jacobson
Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(6):1072-82.
2005: Jennifer Wingard; Jenny Chan; Ivan Bosanac; Francoise Haeseleer; Krzysztof Palczewski; Mitsuhiko Ikura; James B Ames
Structural analysis of Mg2+ and Ca2+ binding to CaBP1, a neuron-specific regulator of calcium channels.
The Journal of biological chemistry 2005;280(45):37461-70.
2005: Li Zhang; David Salom; Jianhua He; Alex Okun; Juan A Ballesteros; Krzysztof Palczewski; Ning Li
Expression of functional G protein-coupled receptors in photoreceptors of transgenic Xenopus laevis.
Biochemistry 2005;44(44):14509-18.
2005: Matthew L Batten; Yoshikazu Imanishi; Daniel C Tu; Thuy Doan; Li Zhu; Jijing Pang; Lyudmila Glushakova; Alexander R Moise; Wolfgang Baehr; Russell N Van Gelder; William W Hauswirth; Fred Rieke; Krzysztof Palczewski
Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis.
PLoS medicine 2005;2(11):e333.
2005: Tadao Maeda; Janis Lem; Krzysztof Palczewski; Francoise Haeseleer
A critical role of CaBP4 in the cone synapse.
Investigative ophthalmology & visual science 2005;46(11):4320-7.
2005: Sheila M O'Byrne; Nuttaporn Wongsiriroj; Jenny Libien; Silke Vogel; Ira J Goldberg; Wolfgang Baehr; Krzysztof Palczewski; William S Blaner
Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT).
The Journal of biological chemistry 2005;280(42):35647-57.
2005: Franz J Bartl; Olaf Fritze; Eglof Ritter; Rolf Herrmann; Vladimir Kuksa; Krzysztof Palczewski; Klaus Peter Hofmann; Oliver P Ernst
Partial agonism in a G Protein-coupled receptor: role of the retinal ring structure in rhodopsin activation.
The Journal of biological chemistry 2005;280(40):34259-67.
2005: Paul S-H Park; Krzysztof Palczewski
Imaging G protein-coupled receptor islands.
Nature chemical biology 2005;1(4):184-5.
2005: Alexander R Moise; Vladimir Kuksa; William S Blaner; Wolfgang Baehr; Krzysztof Palczewski
Metabolism and transactivation activity of 13,14-dihydroretinoic acid.
The Journal of biological chemistry 2005;280(30):27815-25.
2005: Paul S-H Park; Krzysztof Palczewski
Diversifying the repertoire of G protein-coupled receptors through oligomerization.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(25):8793-4.
2005: Marcin Golczak; Vladimir Kuksa; Tadao Maeda; Alexander R Moise; Krzysztof Palczewski
Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(23):8162-7.
2005: Ronald E Stenkamp; David C Teller; Krzysztof Palczewski
Rhodopsin: a structural primer for G-protein coupled receptors.
Archiv der Pharmazie 2005;338(5-6):209-16.
2005: Akiko Maeda; Tadao Maeda; Yoshikazu Imanishi; Vladimir Kuksa; Andrei Alekseev; J Darin Bronson; Houbin Zhang; Li Zhu; Wenyu Sun; David A Saperstein; Fred Rieke; Wolfgang Baehr; Krzysztof Palczewski
Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo.
The Journal of biological chemistry 2005;280(19):18822-32.
2005: Samuel G Jacobson; Tomas S Aleman; Artur Vahe Cideciyan; Alexander Sumaroka; Sharon B Schwartz; Elizabeth A M Windsor; Elias Traboulsi; Elise Heon; Steven J Pittler; Ann H Milam; Albert M Maguire; Krzysztof Palczewski; Edwin M Stone; Jean Bennett
Identifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy success.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(17):6177-82.
2005: Alexander R Moise; Johannes Von Lintig; Krzysztof Palczewski
Related enzymes solve evolutionarily recurrent problems in the metabolism of carotenoids.
Trends in plant science 2005;10(4):178-86.
2005: Izabela Sokal; William Dupps; Michael Grassi; Jeremiah Brown; Louisa M Affatigato; Nirmalya Roychowdhury; Lili Yang; Slawomir Filipek; Krzysztof Palczewski; Edwin M Stone; Wolfgang Baehr
A novel GCAP1 missense mutation (L151F) in a large family with autosomal dominant cone-rod dystrophy (adCORD).
Investigative ophthalmology & visual science 2005;46(4):1124-32.
2005: Tom S Kim; Akiko Maeda; Tadao Maeda; Cynthia Heinlein; Natalia Y Kedishvili; Krzysztof Palczewski; Peter S Nelson
Delayed dark adaptation in 11-cis-retinol dehydrogenase-deficient mice: a role of RDH11 in visual processes in vivo.
The Journal of biological chemistry 2005;280(10):8694-704.
2005: Akiko Maeda; John W Crabb; Krzysztof Palczewski
Microsomal glutathione S-transferase 1 in the retinal pigment epithelium: protection against oxidative stress and a potential role in aging.
Biochemistry 2005;44(2):480-9.
2004: Beata Jastrzebska; Tadao Maeda; Li Zhu; Dimitrios Fotiadis; Slawomir Filipek; Andreas Engel; Ronald E Stenkamp; Krzysztof Palczewski
Functional characterization of rhodopsin monomers and dimers in detergents.
The Journal of biological chemistry 2004;279(52):54663-75.
2004: Paul S-H Park; Slawomir Filipek; James W Wells; Krzysztof Palczewski
Oligomerization of G protein-coupled receptors: past, present, and future.
Biochemistry 2004;43(50):15643-56.
2004: Li Zhu; Geeng-Fu Jang; Beata Jastrzebska; Slawomir Filipek; Susan E Pearce-Kelling; Gustavo D Aguirre; Ronald E Stenkamp; Gregory M Acland; Krzysztof Palczewski
A naturally occurring mutation of the opsin gene (T4R) in dogs affects glycosylation and stability of the G protein-coupled receptor.
The Journal of biological chemistry 2004;279(51):53828-39.
2004: Alexander R Moise; Vladimir Kuksa; Yoshikazu Imanishi; Krzysztof Palczewski
Identification of all-trans-retinol:all-trans-13,14-dihydroretinol saturase.
The Journal of biological chemistry 2004;279(48):50230-42.
2004: Yan Liang; Dimitrios Fotiadis; Tadao Maeda; Akiko Maeda; Anna Modzelewska; Slawomir Filipek; David A Saperstein; Andreas Engel; Krzysztof Palczewski
Rhodopsin signaling and organization in heterozygote rhodopsin knockout mice.
The Journal of biological chemistry 2004;279(46):48189-96.
2004: Kitaru Suda; Slawomir Filipek; Krzysztof Palczewski; Andreas Engel; Dimitrios Fotiadis
The supramolecular structure of the GPCR rhodopsin in solution and native disc membranes.
Molecular membrane biology 2004;21(6):435-46.
2004: Koji M Nishiguchi; Izabela Sokal; Lili Yang; Nirmalya Roychowdhury; Krzysztof Palczewski; Eliot L Berson; Thaddeus P Dryja; Wolfgang Baehr
A novel mutation (I143NT) in guanylate cyclase-activating protein 1 (GCAP1) associated with autosomal dominant cone degeneration.
Investigative ophthalmology & visual science 2004;45(11):3863-70.
2004: Daniel C Tu; Matthew L Batten; Krzysztof Palczewski; Russell N Van Gelder
Nonvisual photoreception in the chick iris.
Science (New York, N.Y.) 2004;306(5693):129-31.
2004: Francoise Haeseleer; Yoshikazu Imanishi; Tadao Maeda; Daniel E Possin; Akiko Maeda; Amy Lee; Fred Rieke; Krzysztof Palczewski
Essential role of Ca2+-binding protein 4, a Cav1.4 channel regulator, in photoreceptor synaptic function.
Nature neuroscience 2004;7(10):1079-87.
2004: Alex Mammen; P Jeanette Simpson; Alex Mamman; Jeanette P Simpson; Alan Nighorn; Yoshikazu Imanishi; Krzysztof Palczewski; Gabriele V Ronnett; Cheil Moon
Hippocalcin in the olfactory epithelium: a mediator of second messenger signaling.
Biochemical and biophysical research communications 2004;322(4):1131-9.
2004: Krzysztof Palczewski; Izabela Sokal; Wolfgang Baehr
Guanylate cyclase-activating proteins: structure, function, and diversity.
Biochemical and biophysical research communications 2004;322(4):1123-30.
2004: Lalita Subramanian; John W Crabb; Jos Cox; Isabelle Durussel; Teresa M Walker; Paul R Van Ginkel; Saswati Bhattacharya; Julia M Dellaria; Krzysztof Palczewski; Arthur S Polans
Ca2+ binding to EF hands 1 and 3 is essential for the interaction of apoptosis-linked gene-2 with Alix/AIP1 in ocular melanoma.
Biochemistry 2004;43(35):11175-86.
2004: Yoshikazu Imanishi; Volker Gerke; Krzysztof Palczewski
Retinosomes: new insights into intracellular managing of hydrophobic substances in lipid bodies.
The Journal of cell biology 2004;166(4):447-53.
2004: Yoshikazu Imanishi; Lili Yang; Izabela Sokal; Slawomir Filipek; Krzysztof Palczewski; Wolfgang Baehr
Diversity of guanylate cyclase-activating proteins (GCAPs) in teleost fish: characterization of three novel GCAPs (GCAP4, GCAP5, GCAP7) from zebrafish (Danio rerio) and prediction of eight GCAPs (GCAP1-8) in pufferfish (Fugu rubripes).
Journal of molecular evolution 2004;59(2):204-17.
2004: Slawomir Filipek; Krystiana A Krzysko; Dimitrios Fotiadis; Yan Liang; David A Saperstein; Andreas Engel; Krzysztof Palczewski
A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2004;3(6):628-38.
2004: Dimitrios Fotiadis; Yan Liang; Slawomir Filipek; David A Saperstein; Andreas Engel; Krzysztof Palczewski
The G protein-coupled receptor rhodopsin in the native membrane.
FEBS letters 2004;564(3):281-8.
2004: Tomas S Aleman; Samuel G Jacobson; John D Chico; Michele L Scott; Andy Y Cheung; Elizabeth A M Windsor; Masatoshi Furushima; T Michael Redmond; Jean Bennett; Krzysztof Palczewski; Artur Vahe Cideciyan
Impairment of the transient pupillary light reflex in Rpe65(-/-) mice and humans with leber congenital amaurosis.
Investigative ophthalmology & visual science 2004;45(4):1259-71.
2004: Matthew L Batten; Yoshikazu Imanishi; Tadao Maeda; Daniel C Tu; Alexander R Moise; Darin Bronson; Daniel E Possin; Russell N Van Gelder; Wolfgang Baehr; Krzysztof Palczewski
Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver.
The Journal of biological chemistry 2004;279(11):10422-32.
2004: Yoshikazu Imanishi; Matthew L Batten; David W Piston; Wolfgang Baehr; Krzysztof Palczewski
Noninvasive two-photon imaging reveals retinyl ester storage structures in the eye.
The Journal of cell biology 2004;164(3):373-83.
2003: Carola A G G Driessen; Huub J Winkens; Francoise Haeseleer; Krzysztof Palczewski; Jacques Janssen
Novel targeting strategy for generating mouse models with defects in the retinoid cycle.
Vision research 2003;43(28):3075-9.
2003: Vladimir Kuksa; Yoshikazu Imanishi; Matthew L Batten; Krzysztof Palczewski; Alexander R Moise
Retinoid cycle in the vertebrate retina: experimental approaches and mechanisms of isomerization.
Vision research 2003;43(28):2959-81.
2003: Wolfgang Baehr; Samuel M Wu; Alan C Bird; Krzysztof Palczewski
The retinoid cycle and retina disease.
Vision research 2003;43(28):2957-8.
2003: David C Teller; Ronald E Stenkamp; Krzysztof Palczewski
Evolutionary analysis of rhodopsin and cone pigments: connecting the three-dimensional structure with spectral tuning and signal transfer.
FEBS letters 2003;555(1):151-9.
2003: Kevin D Ridge; Najmoutin G Abdulaev; Marcelo Sousa; Krzysztof Palczewski
Phototransduction: crystal clear.
Trends in biochemical sciences 2003;28(9):479-87.
2003: Michael F Marmor; Francoise Haeseleer; Krzysztof Palczewski
Albipunctate retinopathy with cone dysfunction and no abnormality in the RDH5 or RLBP1 genes.
Retina (Philadelphia, Pa.) 2003;23(4):543-6.
2003: Sandra A Schadel; Martin Heck; Dieter Maretzki; Slawomir Filipek; David C Teller; Krzysztof Palczewski; Klaus Peter Hofmann
Ligand channeling within a G-protein-coupled receptor. The entry and exit of retinals in native opsin.
The Journal of biological chemistry 2003;278(27):24896-903.
2003: Tadao Maeda; Yoshikazu Imanishi; Krzysztof Palczewski
Rhodopsin phosphorylation: 30 years later.
Progress in retinal and eye research 2003;22(4):417-34.
2003: Yan Liang; Dimitrios Fotiadis; Slawomir Filipek; David A Saperstein; Krzysztof Palczewski; Andreas Engel
Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes.
The Journal of biological chemistry 2003;278(24):21655-62.
2003: Tadao Maeda; J Preston Van Hooser; Carola A G G Driessen; Slawomir Filipek; Jacques J M Janssen; Krzysztof Palczewski
Evaluation of the role of the retinal G protein-coupled receptor (RGR) in the vertebrate retina in vivo.
Journal of neurochemistry 2003;85(4):944-56.
2003: Syed M Noorwez; Vladimir Kuksa; Yoshikazu Imanishi; Li Zhu; Slawomir Filipek; Krzysztof Palczewski; Shalesh Kaushal
Pharmacological chaperone-mediated in vivo folding and stabilization of the P23H-opsin mutant associated with autosomal dominant retinitis pigmentosa.
The Journal of biological chemistry 2003;278(16):14442-50.
2003: Tara Mirzadegan; Gil Benkö; Sławomir Filipek; Krzysztof Palczewski
Sequence analyses of G-protein-coupled receptors: similarities to rhodopsin.
Biochemistry 2003;42(10):2759-67.
2003: Izabela Sokal; Guang Hu; Yan Liang; Muling Mao; Theodore G Wensel; Krzysztof Palczewski
Identification of protein kinase C isozymes responsible for the phosphorylation of photoreceptor-specific RGS9-1 at Ser475.
The Journal of biological chemistry 2003;278(10):8316-25.
2003: Olaf Fritze; Slawomir Filipek; Vladimir Kuksa; Krzysztof Palczewski; Klaus Peter Hofmann; Oliver P Ernst
Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2290-5.
2003: Martin Heck; Sandra A Schädel; Dieter Maretzki; Franz J Bartl; Eglof Ritter; Krzysztof Palczewski; Klaus Peter Hofmann
Signaling states of rhodopsin. Formation of the storage form, metarhodopsin III, from active metarhodopsin II.
The Journal of biological chemistry 2003;278(5):3162-9.
2003: Dimitrios Fotiadis; Yan Liang; Slawomir Filipek; David A Saperstein; Andreas Engel; Krzysztof Palczewski
Atomic-force microscopy: Rhodopsin dimers in native disc membranes.
Nature 2003;421(6919):127-8.
2003: Izabela Sokal; Andrei Alekseev; Krzysztof Palczewski
Photoreceptor guanylate cyclase variants: cGMP production under control.
Acta biochimica Polonica 2003;50(4):1075-95.
2003: Slawomir Filipek; David C Teller; Krzysztof Palczewski; Ronald E Stenkamp
The crystallographic model of rhodopsin and its use in studies of other G protein-coupled receptors.
Annual review of biophysics and biomolecular structure 2003;32():375-97.
2003: Slawomir Filipek; Ronald E Stenkamp; David C Teller; Krzysztof Palczewski
G protein-coupled receptor rhodopsin: a prospectus.
Annual review of physiology 2003;65():851-79.
2002: Francoise Haeseleer; Geeng-Fu Jang; Yoshikazu Imanishi; Carola A G G Driessen; Masazumi Matsumura; Peter S Nelson; Krzysztof Palczewski
Dual-substrate specificity short chain retinol dehydrogenases from the vertebrate retina.
The Journal of biological chemistry 2002;277(47):45537-46.
2002: Vladimir Kuksa; Franz J Bartl; Tadao Maeda; Geeng-Fu Jang; Eglof Ritter; Martin Heck; J Preston Van Hooser; Yan Liang; Slawomir Filipek; Michael H Gelb; Klaus Peter Hofmann; Krzysztof Palczewski
Biochemical and physiological properties of rhodopsin regenerated with 11-cis-6-ring- and 7-ring-retinals.
The Journal of biological chemistry 2002;277(44):42315-24.
2002: Ronald E Stenkamp; Slawomir Filipek; Carola A G G Driessen; David C Teller; Krzysztof Palczewski
Crystal structure of rhodopsin: a template for cone visual pigments and other G protein-coupled receptors.
Biochimica et biophysica acta 2002;1565(2):168-82.
2002: Ronald E Stenkamp; David C Teller; Krzysztof Palczewski
Crystal structure of rhodopsin: a G-protein-coupled receptor.
Chembiochem : a European journal of chemical biology 2002;3(10):963-7.
2002: Akiko Maeda; Tadao Maeda; Hiroshi Ohguro; Krzysztof Palczewski; Noriyuki Sato
Vaccination with recoverin, a cancer-associated retinopathy antigen, induces autoimmune retinal dysfunction and tumor cell regression in mice.
European journal of immunology 2002;32(8):2300-7.
2002: Jun Yang; Sean M J McBride; Don-On Daniel Mak; Noga Vardi; Krzysztof Palczewski; Francoise Haeseleer; J Kevin Foskett
Identification of a family of calcium sensors as protein ligands of inositol trisphosphate receptor Ca(2+) release channels.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(11):7711-6.
2002: J Preston Van Hooser; Yan Liang; Tadao Maeda; Vladimir Kuksa; Geeng-Fu Jang; Yu-Guang He; Fred Rieke; Henry K W Fong; Peter B Detwiler; Krzysztof Palczewski
Recovery of visual functions in a mouse model of Leber congenital amaurosis.
The Journal of biological chemistry 2002;277(21):19173-82.
2002: Kimberly Howes; Mark Pennesi; Izabela Sokal; Jill Church-Kopish; Ben Schmidt; David Margolis; Jeanne M Frederick; Fred Rieke; Krzysztof Palczewski; Samuel M Wu; Peter B Detwiler; Wolfgang Baehr
GCAP1 rescues rod photoreceptor response in GCAP1/GCAP2 knockout mice.
The EMBO journal 2002;21(7):1545-54.
2002: Amy Lee; Ruth E Westenbroek; Francoise Haeseleer; Krzysztof Palczewski; Todd Scheuer; William A Catterall
Differential modulation of Ca(v)2.1 channels by calmodulin and Ca2+-binding protein 1.
Nature neuroscience 2002;5(3):210-7.
2002: Francoise Haeseleer; Yoshikazu Imanishi; Izabela Sokal; Slawomir Filipek; Krzysztof Palczewski
Calcium-binding proteins: intracellular sensors from the calmodulin superfamily.
Biochemical and biophysical research communications 2002;290(2):615-23.
2002: Izabela Sokal; Andrei Alekseev; Wolfgang Baehr; Francoise Haeseleer; Krzysztof Palczewski
Soluble fusion proteins between single transmembrane photoreceptor guanylyl cyclases and their activators.
Biochemistry 2002;41(1):251-7.
2002: Francoise Haeseleer; Krzysztof Palczewski
Calmodulin and Ca2+-binding proteins (CaBPs): variations on a theme.
Advances in experimental medicine and biology 2002;514():303-17.
2002: Yoshikazu Imanishi; Ning Li; Izabela Sokal; Mathew E Sowa; Olivier Lichtarge; Theodore G Wensel; David A Saperstein; Wolfgang Baehr; Krzysztof Palczewski
Characterization of retinal guanylate cyclase-activating protein 3 (GCAP3) from zebrafish to man.
The European journal of neuroscience 2002;15(1):63-78.
2002: Izabela Sokal; Alexander Pulvermüller; Janina Buczyłko; Klaus Peter Hofmann; Krzysztof Palczewski
Rhodopsin and its kinase.
Methods in enzymology 2002;343():578-600.
2001: JK McBee; J Preston Van Hooser; Geeng-Fu Jang; Krzysztof Palczewski
Isomerization of 11-cis-retinoids to all-trans-retinoids in vitro and in vivo.
The Journal of biological chemistry 2001;276(51):48483-93.
2001: Francoise Haeseleer; Yoshikazu Imanishi; David A Saperstein; Krzysztof Palczewski
Gene transfer mediated by recombinant baculovirus into mouse eye.
Investigative ophthalmology & visual science 2001;42(13):3294-300.
2001: Izabela Sokal; Ning Li; C S Klug; Slawomir Filipek; W L Hubbell; Wolfgang Baehr; Krzysztof Palczewski
Calcium-sensitive regions of GCAP1 as observed by chemical modifications, fluorescence, and EPR spectroscopies.
The Journal of biological chemistry 2001;276(46):43361-73.
2001: Geeng-Fu Jang; J Preston Van Hooser; Vladimir Kuksa; JK McBee; Yu-Guang He; Jacques J M Janssen; Carola A G G Driessen; Krzysztof Palczewski
Characterization of a dehydrogenase activity responsible for oxidation of 11-cis-retinol in the retinal pigment epithelium of mice with a disrupted RDH5 gene. A model for the human hereditary disease fundus albipunctatus.
The Journal of biological chemistry 2001;276(35):32456-65.
2001: Ning Li; Izabela Sokal; J Darin Bronson; Krzysztof Palczewski; Wolfgang Baehr
Identification of functional regions of guanylate cyclase-activating protein 1 (GCAP1) using GCAP1/GCIP chimeras.
Biological chemistry 2001;382(8):1179-88.
2001: Geeng-Fu Jang; Vladimir Kuksa; Slawomir Filipek; Franz J Bartl; Eglof Ritter; Michael H Gelb; Klaus Peter Hofmann; Krzysztof Palczewski
Mechanism of rhodopsin activation as examined with ring-constrained retinal analogs and the crystal structure of the ground state protein.
The Journal of biological chemistry 2001;276(28):26148-53.
2001: David C Teller; T Okada; Craig Behnke; Krzysztof Palczewski; Ronald E Stenkamp
Advances in determination of a high-resolution three-dimensional structure of rhodopsin, a model of G-protein-coupled receptors (GPCRs).
Biochemistry 2001;40(26):7761-72.
2001: JK McBee; Krzysztof Palczewski; Wolfgang Baehr; David R Pepperberg
Confronting complexity: the interlink of phototransduction and retinoid metabolism in the vertebrate retina.
Progress in retinal and eye research 2001;20(4):469-529.
2001: T Okada; O P Ernst; Krzysztof Palczewski; Klaus Peter Hofmann
Activation of rhodopsin: new insights from structural and biochemical studies.
Trends in biochemical sciences 2001;26(5):318-24.
2001: W Yan; G F Jang; Francoise Haeseleer; Noriko Esumi; J Chang; M Kerrigan; M Campochiaro; Peter A Campochiaro; Krzysztof Palczewski; Donald J Zack
Cloning and characterization of a human beta,beta-carotene-15,15'-dioxygenase that is highly expressed in the retinal pigment epithelium.
Genomics 2001;72(2):193-202.
2000: Izabela Sokal; Ning Li; Christophe Verlinde; Francoise Haeseleer; Wolfgang Baehr; Krzysztof Palczewski
Ca(2+)-binding proteins in the retina: from discovery to etiology of human disease(1).
Biochimica et biophysica acta 2000;1498(2-3):233-51.
2000: JK McBee; Vladimir Kuksa; R Alvarez; A R de Lera; O Prezhdo; Francoise Haeseleer; Izabela Sokal; Krzysztof Palczewski
Isomerization of all-trans-retinol to cis-retinols in bovine retinal pigment epithelial cells: dependence on the specificity of retinoid-binding proteins.
Biochemistry 2000;39(37):11370-80.
2000: Geeng-Fu Jang; JK McBee; A M Alekseev; Francoise Haeseleer; Krzysztof Palczewski
Stereoisomeric specificity of the retinoid cycle in the vertebrate retina.
The Journal of biological chemistry 2000;275(36):28128-38.
2000: Artur Vahe Cideciyan; Francoise Haeseleer; Robert Fariss; Tomas S Aleman; G F Jang; Christophe Verlinde; Michael F Marmor; Samuel G Jacobson; Krzysztof Palczewski
Rod and cone visual cycle consequences of a null mutation in the 11-cis-retinol dehydrogenase gene in man.
Visual neuroscience 2000;17(5):667-78.
2000: Krzysztof Palczewski; Takashi Kumasaka; T Hori; Craig Behnke; H Motoshima; B A Fox; Isolde Le Trong; David C Teller; T Okada; Ronald E Stenkamp; Masaki Yamamoto; M Miyano
Crystal structure of rhodopsin: A G protein-coupled receptor.
Science (New York, N.Y.) 2000;289(5480):739-45.
2000: J Preston Van Hooser; Tomas S Aleman; Yu-Guang He; Artur Vahe Cideciyan; Vladimir Kuksa; S J Pittler; E M Stone; S G Jacobson; Krzysztof Palczewski
Rapid restoration of visual pigment and function with oral retinoid in a mouse model of childhood blindness.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(15):8623-8.
2000: Carola A G G Driessen; Huub J Winkens; K Hoffmann; LD Kuhlmann; B P M Janssen; AH van Vugt; J Preston Van Hooser; B E Wieringa; August F Deutman; Krzysztof Palczewski; K Ruether; Jacques J M Janssen
Disruption of the 11-cis-retinol dehydrogenase gene leads to accumulation of cis-retinols and cis-retinyl esters.
Molecular and cellular biology 2000;20(12):4275-87.
2000: T Okada; Isolde Le Trong; B A Fox; Craig Behnke; Ronald E Stenkamp; Krzysztof Palczewski
X-Ray diffraction analysis of three-dimensional crystals of bovine rhodopsin obtained from mixed micelles.
Journal of structural biology 2000;130(1):73-80.
2000: Krzysztof Palczewski; A S Polans; Wolfgang Baehr; James B Ames
Ca(2+)-binding proteins in the retina: structure, function, and the etiology of human visual diseases.
BioEssays : news and reviews in molecular, cellular and developmental biology 2000;22(4):337-50.
2000: Francoise Haeseleer; Izabela Sokal; Christophe Verlinde; H Erdjument-Bromage; Paul Tempst; A N Pronin; J L Benovic; Robert Fariss; Krzysztof Palczewski
Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin.
The Journal of biological chemistry 2000;275(2):1247-60.
2000: M E Whitten; Kohei Yokoyama; DM Schieltz; Farideh Ghomashchi; D Lam; John R Yates; Krzysztof Palczewski; Michael H Gelb
Structural analysis of protein prenyl groups and associated C-terminal modifications.
Methods in enzymology 2000;316():436-51.
2000: Francoise Haeseleer; Krzysztof Palczewski
Short-chain dehydrogenases/reductases in retina.
Methods in enzymology 2000;316():372-83.
2000: John C Saari; Gregory G Garwin; Francoise Haeseleer; Geeng-Fu Jang; Krzysztof Palczewski
Phase partition and high-performance liquid chromatography assays of retinoid dehydrogenases.
Methods in enzymology 2000;316():359-71.
2000: Hartmut Stecher; Krzysztof Palczewski
Multienzyme analysis of visual cycle.
Methods in enzymology 2000;316():330-44.
1999: Kang Zhang; Kimberly Howes; W He; J Darin Bronson; M J Pettenati; C Chen; Krzysztof Palczewski; Theodore G Wensel; Wolfgang Baehr
Structure, alternative splicing, and expression of the human RGS9 gene.
Gene 1999;240(1):23-34.
1999: Hartmut Stecher; Oleg V Prezhdo; J Das; Rosalie K Crouch; Krzysztof Palczewski
Isomerization of all-trans-9- and 13-desmethylretinol by retinal pigment epithelial cells.
Biochemistry 1999;38(41):13542-50.
1999: Krzysztof Palczewski; J Preston Van Hooser; Gregory G Garwin; Jeannie Chen; Gregory I Liou; John C Saari
Kinetics of visual pigment regeneration in excised mouse eyes and in mice with a targeted disruption of the gene encoding interphotoreceptor retinoid-binding protein or arrestin.
Biochemistry 1999;38(37):12012-9.
1999: Izabela Sokal; AE Otto-Bruc; Irina Surgucheva; Christophe Verlinde; C K Wang; Wolfgang Baehr; Krzysztof Palczewski
Conformational changes in guanylyl cyclase-activating protein 1 (GCAP1) and its tryptophan mutants as a function of calcium concentration.
The Journal of biological chemistry 1999;274(28):19829-37.
1999: X Zhao; Kohei Yokoyama; M E Whitten; Jing Huang; Michael H Gelb; Krzysztof Palczewski
A novel form of rhodopsin kinase from chicken retina and pineal gland.
FEBS letters 1999;454(1-2):115-21.
1999: James B Ames; Alexander M Dizhoor; Mitsuhiko Ikura; Krzysztof Palczewski; L Stryer
Three-dimensional structure of guanylyl cyclase activating protein-2, a calcium-sensitive modulator of photoreceptor guanylyl cyclases.
The Journal of biological chemistry 1999;274(27):19329-37.
1999: Hartmut Stecher; Michael H Gelb; John C Saari; Krzysztof Palczewski
Preferential release of 11-cis-retinol from retinal pigment epithelial cells in the presence of cellular retinaldehyde-binding protein.
The Journal of biological chemistry 1999;274(13):8577-85.
1999: Francoise Haeseleer; Izabela Sokal; Ning Li; M Pettenati; N Rao; Darin Bronson; R Wechter; Wolfgang Baehr; Krzysztof Palczewski
Molecular characterization of a third member of the guanylyl cyclase-activating protein subfamily.
The Journal of biological chemistry 1999;274(10):6526-35.
1999: Izabela Sokal; Francoise Haeseleer; Anatol Arendt; Elinor T Adman; Paul A Hargrave; Krzysztof Palczewski
Identification of a guanylyl cyclase-activating protein-binding site within the catalytic domain of retinal guanylyl cyclase 1.
Biochemistry 1999;38(5):1387-93.
1999: Krzysztof Palczewski; Christophe Verlinde; Francoise Haeseleer
Molecular mechanism of visual transduction.
Novartis Foundation symposium 1999;224():191-204; discussion 204-7.
1998: AE Otto-Bruc; Robert Fariss; J Preston Van Hooser; Krzysztof Palczewski
Phosphorylation of photolyzed rhodopsin is calcium-insensitive in retina permeabilized by alpha-toxin.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(25):15014-9.
1998: Francoise Haeseleer; Jing Huang; Lukasz Lebioda; John C Saari; Krzysztof Palczewski
Molecular characterization of a novel short-chain dehydrogenase/reductase that reduces all-trans-retinal.
The Journal of biological chemistry 1998;273(34):21790-9.
1998: Izabela Sokal; Ning Li; Irina Surgucheva; Martin J Warren; Annette M Payne; S S Bhattacharya; Wolfgang Baehr; Krzysztof Palczewski
GCAP1 (Y99C) mutant is constitutively active in autosomal dominant cone dystrophy.
Molecular cell 1998;2(1):129-33.
1998: John C Saari; Gregory G Garwin; J Preston Van Hooser; Krzysztof Palczewski
Reduction of all-trans-retinal limits regeneration of visual pigment in mice.
Vision research 1998;38(10):1325-33.
1998: Cheil Moon; P Jaberi; AE Otto-Bruc; Wolfgang Baehr; Krzysztof Palczewski; Gabriele V Ronnett
Calcium-sensitive particulate guanylyl cyclase as a modulator of cAMP in olfactory receptor neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(9):3195-205.
1998: Ning Li; Robert Fariss; Kang Zhang; AE Otto-Bruc; Francoise Haeseleer; Darin Bronson; N Qin; Akio Yamazaki; I Subbaraya; Ann H Milam; Krzysztof Palczewski; Wolfgang Baehr
Guanylate-cyclase-inhibitory protein is a frog retinal Ca2+-binding protein related to mammalian guanylate-cyclase-activating proteins.
European journal of biochemistry / FEBS 1998;252(3):591-9.
1998: X Zhao; Jing Huang; S C Khani; Krzysztof Palczewski
Molecular forms of human rhodopsin kinase (GRK1).
The Journal of biological chemistry 1998;273(9):5124-31.
1998: Susan L Semple-Rowland; N R Lee; J P Van Hooser; Krzysztof Palczewski; Wolfgang Baehr
A null mutation in the photoreceptor guanylate cyclase gene causes the retinal degeneration chicken phenotype.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(3):1271-6.
1998: M Rudnicka-Nawrot; Irina Surgucheva; JD Hulmes; Francoise Haeseleer; Izabela Sokal; John W Crabb; Wolfgang Baehr; Krzysztof Palczewski
Changes in biological activity and folding of guanylate cyclase-activating protein 1 as a function of calcium.
Biochemistry 1998;37(1):248-57.
1998: Artur Vahe Cideciyan; X Zhao; L Nielsen; Shahrokh C Khani; Samuel G Jacobson; Krzysztof Palczewski
Null mutation in the rhodopsin kinase gene slows recovery kinetics of rod and cone phototransduction in man.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(1):328-33.
1997: Krzysztof Palczewski
GTP-binding-protein-coupled receptor kinases--two mechanistic models.
European journal of biochemistry / FEBS 1997;248(2):261-9.
1997: Krzysztof Palczewski; John C Saari
Activation and inactivation steps in the visual transduction pathway.
Current opinion in neurobiology 1997;7(4):500-4.
1997: Alexander Pulvermüller; Dieter Maretzki; M Rudnicka-Nawrot; W C Smith; Krzysztof Palczewski; Klaus Peter Hofmann
Functional differences in the interaction of arrestin and its splice variant, p44, with rhodopsin.
Biochemistry 1997;36(30):9253-60.
1997: AE Otto-Bruc; Robert Fariss; Francoise Haeseleer; Jing Huang; J Buczyłko; Irina Surgucheva; Wolfgang Baehr; Ann H Milam; Krzysztof Palczewski
Localization of guanylate cyclase-activating protein 2 in mammalian retinas.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4727-32.
1997: AE Otto-Bruc; J Buczylko; Irina Surgucheva; I Subbaraya; M Rudnicka-Nawrot; John W Crabb; Anatol Arendt; Paul A Hargrave; Wolfgang Baehr; Krzysztof Palczewski
Functional reconstitution of photoreceptor guanylate cyclase with native and mutant forms of guanylate cyclase-activating protein 1.
Biochemistry 1997;36(14):4295-302.
1997: X Zhao; Francoise Haeseleer; Robert Fariss; Jing Huang; Wolfgang Baehr; Ann H Milam; Krzysztof Palczewski
Molecular cloning and localization of rhodopsin kinase in the mammalian pineal.
Visual neuroscience 1997;14(2):225-32.
1997: Andrei Surguchov; J Darin Bronson; P Banerjee; J A Knowles; C Ruiz; I Subbaraya; Krzysztof Palczewski; Wolfgang Baehr
The human GCAP1 and GCAP2 genes are arranged in a tail-to-tail array on the short arm of chromosome 6 (p21.1).
Genomics 1997;39(3):312-22.
1996: J Buczyłko; John C Saari; Rosalie K Crouch; Krzysztof Palczewski
Mechanisms of opsin activation.
The Journal of biological chemistry 1996;271(34):20621-30.
1996: Teresa Duda; RM Goraczniak; Irina Surgucheva; M Rudnicka-Nawrot; W A Gorczyca; Krzysztof Palczewski; Ari Sitaramayya; Wolfgang Baehr; Rameshwar K Sharma
Calcium modulation of bovine photoreceptor guanylate cyclase.
Biochemistry 1996;35(26):8478-82.
1996: Susan L Semple-Rowland; W A Gorczyca; J Buczylko; B S Helekar; C C Ruiz; I Subbaraya; Krzysztof Palczewski; Wolfgang Baehr
Expression of GCAP1 and GCAP2 in the retinal degeneration (rd) mutant chicken retina.
FEBS letters 1996;385(1-2):47-52.
1996: S Jäger; Krzysztof Palczewski; Klaus Peter Hofmann
Opsin/all-trans-retinal complex activates transducin by different mechanisms than photolyzed rhodopsin.
Biochemistry 1996;35(9):2901-8.
1996: H Ohguro; M Rudnicka-Nawrot; J Buczyłko; X Zhao; J A Taylor; KA Walsh; Krzysztof Palczewski
Structural and enzymatic aspects of rhodopsin phosphorylation.
The Journal of biological chemistry 1996;271(9):5215-24.
1995: W Clay Smith; Grazyna Adamus; H Van Der Wel; Adrian M Timmers; Krzysztof Palczewski; R J Ulshafer; Paul A Hargrave; J Hugh McDowell
Alligator rhodopsin: sequence and biochemical properties.
Experimental eye research 1995;61(5):569-78.
1995: W A Gorczyca; A S Polans; Irina Surgucheva; I Subbaraya; Wolfgang Baehr; Krzysztof Palczewski
Guanylyl cyclase activating protein. A calcium-sensitive regulator of phototransduction.
The Journal of biological chemistry 1995;270(37):22029-36.
1995: X Zhao; Krzysztof Palczewski; H Ohguro
Mechanism of rhodopsin phosphorylation.
Biophysical chemistry 1995;56(1-2):183-8.
1995: H Ohguro; Krzysztof Palczewski
Separation of phospho- and non-phosphopeptides using reverse phase column chromatography.
FEBS letters 1995;368(3):452-4.
1995: Krzysztof Palczewski; H Ohguro; Richard T Premont; James Inglese
Rhodopsin kinase autophosphorylation. Characterization of site-specific mutations.
The Journal of biological chemistry 1995;270(25):15294-8.
1995: H Ohguro; J Preston Van Hooser; Ann H Milam; Krzysztof Palczewski
Rhodopsin phosphorylation and dephosphorylation in vivo.
The Journal of biological chemistry 1995;270(24):14259-62.
1994: I Subbaraya; C C Ruiz; B S Helekar; X Zhao; W A Gorczyca; M J Pettenati; P N Rao; Krzysztof Palczewski; Wolfgang Baehr
Molecular characterization of human and mouse photoreceptor guanylate cyclase-activating protein (GCAP) and chromosomal localization of the human gene.
The Journal of biological chemistry 1994;269(49):31080-9.
1994: H Ohguro; Krzysztof Palczewski; KA Walsh; R S Johnson
Topographic study of arrestin using differential chemical modifications and hydrogen/deuterium exchange.
Protein science : a publication of the Protein Society 1994;3(12):2428-34.
1994: Krzysztof Palczewski; S Jäger; J Buczyłko; Rosalie K Crouch; D L Bredberg; Klaus Peter Hofmann; M A Asson-Batres; John C Saari
Rod outer segment retinol dehydrogenase: substrate specificity and role in phototransduction.
Biochemistry 1994;33(46):13741-50.
1994: R S Morrison; E Shi; M Kan; F Yamaguchi; W McKeehan; M Rudnicka-Nawrot; Krzysztof Palczewski
Inositolhexakisphosphate (InsP6): an antagonist of fibroblast growth factor receptor binding and activity.
In vitro cellular & developmental biology. Animal 1994;30A(11):783-9.
1994: Krzysztof Palczewski
Structure and functions of arrestins.
Protein science : a publication of the Protein Society 1994;3(9):1355-61.
1994: Krzysztof Palczewski
Is vertebrate phototransduction solved? New insights into the molecular mechanism of phototransduction.
Investigative ophthalmology & visual science 1994;35(10):3577-81.
1994: R S Johnson; H Ohguro; Krzysztof Palczewski; James B Hurley; KA Walsh; T A Neubert
Heterogeneous N-acylation is a tissue- and species-specific posttranslational modification.
The Journal of biological chemistry 1994;269(33):21067-71.
1994: Krzysztof Palczewski; I Subbaraya; W A Gorczyca; B S Helekar; C C Ruiz; H Ohguro; Jing Huang; X Zhao; John W Crabb; R S Johnson
Molecular cloning and characterization of retinal photoreceptor guanylyl cyclase-activating protein.
Neuron 1994;13(2):395-404.
1994: Phyllis R Robinson; J Buczyłko; H Ohguro; Krzysztof Palczewski
Opsins with mutations at the site of chromophore attachment constitutively activate transducin but are not phosphorylated by rhodopsin kinase.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(12):5411-5.
1994: W Clay Smith; A H Milam; D Dugger; Anatol Arendt; Paul A Hargrave; Krzysztof Palczewski
A splice variant of arrestin. Molecular cloning and localization in bovine retina.
The Journal of biological chemistry 1994;269(22):15407-10.
1994: W A Gorczyca; M P Gray-Keller; Peter B Detwiler; Krzysztof Palczewski
Purification and physiological evaluation of a guanylate cyclase activating protein from retinal rods.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):4014-8.
1994: W A Gorczyca; J Preston Van Hooser; Krzysztof Palczewski
Nucleotide inhibitors and activators of retinal guanylyl cyclase.
Biochemistry 1994;33(11):3217-22.
1994: A S Polans; Krzysztof Palczewski; M A Asson-Batres; H Ohguro; Danuta Witkowska; T L Haley; L Baizer; John W Crabb
Purification and primary structure of Capl, an S-100-related calcium-binding protein isolated from bovine retina.
The Journal of biological chemistry 1994;269(8):6233-40.
1994: H Ohguro; R S Johnson; L H Ericsson; KA Walsh; Krzysztof Palczewski
Control of rhodopsin multiple phosphorylation.
Biochemistry 1994;33(4):1023-8.
1994: Krzysztof Palczewski; J Buczylko; H Ohguro; Roland S Annan; Steve Carr; John W Crabb; M W Kaplan; R S Johnson; KA Walsh
Characterization of a truncated form of arrestin isolated from bovine rod outer segments.
Protein science : a publication of the Protein Society 1994;3(2):314-24.
1993: A Pulvermüller; Krzysztof Palczewski; Klaus Peter Hofmann
Interaction between photoactivated rhodopsin and its kinase: stability and kinetics of complex formation.
Biochemistry 1993;32(51):14082-8.
1993: John C Saari; D L Bredberg; Gregory G Garwin; J Buczyłko; T Wheeler; Krzysztof Palczewski
Assays of retinoid dehydrogenases by phase partition.
Analytical biochemistry 1993;213(1):128-32.
1993: Grazyna Adamus; Anatol Arendt; Paul A Hargrave; T Heyduk; Krzysztof Palczewski
The kinetics of multiphosphorylation of rhodopsin.
Archives of biochemistry and biophysics 1993;304(2):443-7.
1993: H Ohguro; Krzysztof Palczewski; L H Ericsson; KA Walsh; R S Johnson
Sequential phosphorylation of rhodopsin at multiple sites.
Biochemistry 1993;32(21):5718-24.
1993: Krzysztof Palczewski; J Buczyłko; Lukasz Lebioda; John W Crabb; A S Polans
Identification of the N-terminal region in rhodopsin kinase involved in its interaction with rhodopsin.
The Journal of biological chemistry 1993;268(8):6004-13.
1993: M P Gray-Keller; A S Polans; Krzysztof Palczewski; Peter B Detwiler
The effect of recoverin-like calcium-binding proteins on the photoresponse of retinal rods.
Neuron 1993;10(3):523-31.
1993: A S Polans; M D Burton; T L Haley; John W Crabb; Krzysztof Palczewski
Recoverin, but not visinin, is an autoantigen in the human retina identified with a cancer-associated retinopathy.
Investigative ophthalmology & visual science 1993;34(1):81-90.
1992: Krzysztof Palczewski; J Buczyłko; P Van Hooser; Steve Carr; Michael J Huddleston; John W Crabb
Identification of the autophosphorylation sites in rhodopsin kinase.
The Journal of biological chemistry 1992;267(26):18991-8.
1992: Klaus Peter Hofmann; A Pulvermüller; J Buczyłko; P Van Hooser; Krzysztof Palczewski
The role of arrestin and retinoids in the regeneration pathway of rhodopsin.
The Journal of biological chemistry 1992;267(22):15701-6.
1992: Krzysztof Palczewski; J H Riazance-Lawrence; W Curtis Johnson
Structural properties of arrestin studied by chemical modification and circular dichroism.
Biochemistry 1992;31(16):3902-6.
1992: Krzysztof Palczewski; G Rispoli; Peter B Detwiler
The influence of arrestin (48K protein) and rhodopsin kinase on visual transduction.
Neuron 1992;8(1):117-26.
1991: Krzysztof Palczewski; A Pulvermüller; J Buczylko; C Gutmann; Klaus Peter Hofmann
Binding of inositol phosphates to arrestin.
FEBS letters 1991;295(1-3):195-9.
1991: Krzysztof Palczewski; A Pulvermüller; J Buczyłko; Klaus Peter Hofmann
Phosphorylated rhodopsin and heparin induce similar conformational changes in arrestin.
The Journal of biological chemistry 1991;266(28):18649-54.
1991: Krzysztof Palczewski; J Buczyłko; N R Imami; J Hugh McDowell; Paul A Hargrave
Role of the carboxyl-terminal region of arrestin in binding to phosphorylated rhodopsin.
The Journal of biological chemistry 1991;266(23):15334-9.
1991: Krzysztof Palczewski; J Buczyłko; M W Kaplan; A S Polans; John W Crabb
Mechanism of rhodopsin kinase activation.
The Journal of biological chemistry 1991;266(20):12949-55.
1991: E Ragazzi; John C Shryock; Krzysztof Palczewski
Properties of solubilized and reconstituted A1 adenosine receptors from bovine brain.
Pharmacological research : the official journal of the Italian Pharmacological Society 1991;24(1):15-23.
1991: Krzysztof Palczewski; D B Farber; Paul A Hargrave
Elevated level of protein phosphatase 2A activity in retinas of rd mice.
Experimental eye research 1991;53(1):101-5.
1991: J Buczyłko; C Gutmann; Krzysztof Palczewski
Regulation of rhodopsin kinase by autophosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2568-72.
1991: Krzysztof Palczewski; P A Hargrave
Studies of ligand binding to arrestin.
The Journal of biological chemistry 1991;266(7):4201-6.
1991: A S Polans; J Buczyłko; J Crabb; Krzysztof Palczewski
A photoreceptor calcium binding protein is recognized by autoantibodies obtained from patients with cancer-associated retinopathy.
The Journal of cell biology 1991;112(5):981-9.
1991: Grazyna Adamus; Z S Zam; Anatol Arendt; Krzysztof Palczewski; J Hugh McDowell; Paul A Hargrave
Anti-rhodopsin monoclonal antibodies of defined specificity: characterization and application.
Vision research 1991;31(1):17-31.
1990: Krzysztof Palczewski; N Kahn; Paul A Hargrave
Nucleoside inhibitors of rhodopsin kinase.
Biochemistry 1990;29(26):6276-82.
1990: David W Litchfield; Anatol Arendt; F J Lozeman; Edwin G Krebs; Paul A Hargrave; Krzysztof Palczewski
Synthetic phosphopeptides are substrates for casein kinase II.
FEBS letters 1990;261(1):117-20.
1990: Krzysztof Palczewski; M E Carruth; Grazyna Adamus; J Hugh McDowell; Paul A Hargrave
Molecular, enzymatic and functional properties of rhodopsin kinase from rat pineal gland.
Vision research 1990;30(8):1129-37.
1989: Krzysztof Palczewski; Anatol Arendt; J Hugh McDowell; Paul A Hargrave
Substrate recognition determinants for rhodopsin kinase: studies with synthetic peptides, polyanions, and polycations.
Biochemistry 1989;28(22):8764-70.
1989: Krzysztof Palczewski; J Hugh McDowell; S Jakes; T S Ingebritsen; Paul A Hargrave
Regulation of rhodopsin dephosphorylation by arrestin.
The Journal of biological chemistry 1989;264(27):15770-3.
1989: Anatol Arendt; Krzysztof Palczewski; W T Moore; R M Caprioli; J Hugh McDowell; Paul A Hargrave
Synthesis of phosphopeptides containing O-phosphoserine or O-phosphothreonine.
International journal of peptide and protein research 1989;33(6):468-76.
1989: Krzysztof Palczewski; Paul A Hargrave; J Hugh McDowell; T S Ingebritsen
The catalytic subunit of phosphatase 2A dephosphorylates phosphoopsin.
Biochemistry 1989;28(2):415-9.
1988: Krzysztof Palczewski; J Hugh McDowell; Paul A Hargrave
Purification and characterization of rhodopsin kinase.
The Journal of biological chemistry 1988;263(28):14067-73.
1988: Krzysztof Palczewski; J Hugh McDowell; Paul A Hargrave
Rhodopsin kinase: substrate specificity and factors that influence activity.
Biochemistry 1988;27(7):2306-13.