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Carlos Palmeira

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Fernanda M Ferreira; Maria M Oliveira; Carlos M Palmeira; Sílvia M Rocha; Dario Santos; Anabela M Simões; Manuel A Coimbra; Francisco Peixoto
Nerolidol effects on mitochondrial and cellular energetics.
Carlos M Palmeira; Anabela P Rolo
Mitochondrial membrane potential (ΔΨ) fluctuations associated with the metabolic states of mitochondria.
Filipe V Duarte; Anabela P Rolo; Anabela M Simões; João S Teodoro; Carlos M Palmeira
Exposure to dibenzofuran affects lung mitochondrial function in vitro.

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All Publications

2012: Fernanda M Ferreira; Maria M Oliveira; Carlos M Palmeira; Sílvia M Rocha; Dario Santos; Anabela M Simões; Manuel A Coimbra; Francisco Peixoto
Nerolidol effects on mitochondrial and cellular energetics.
Toxicology in vitro : an international journal published in association with BIBRA 2012;26(2):189-96.
2012: Carlos M Palmeira; Anabela P Rolo
Mitochondrial membrane potential (ΔΨ) fluctuations associated with the metabolic states of mitochondria.
Methods in molecular biology (Clifton, N.J.) 2012;810():89-101.
2011: Filipe V Duarte; Anabela P Rolo; Anabela M Simões; João S Teodoro; Carlos M Palmeira
Exposure to dibenzofuran affects lung mitochondrial function in vitro.
Toxicology mechanisms and methods 2011;21(8):571-6.
2011: Anabela P Rolo; Ana P Gomes; Carlos M Palmeira
Regulation of mitochondrial biogenesis in metabolic syndrome.
Current drug targets 2011;12(6):872-8.
2011: João S Teodoro; Anabela M Simões; Filipe V Duarte; Anabela P Rolo; Richard C Murdoch; Saber M Hussain; Carlos M Palmeira
Assessment of the toxicity of silver nanoparticles in vitro: a mitochondrial perspective.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(3):664-70.
2011: Ana T Varela; Anabela P Rolo; Carlos M Palmeira
Fatty liver and ischemia/reperfusion: are there drugs able to mitigate injury?
Current medicinal chemistry 2011;18(32):4987-5002.
2010: Ana T Varela; Anabela M Simões; João S Teodoro; Filipe V Duarte; Ana P Gomes; Carlos M Palmeira; Anabela P Rolo
Indirubin-3'-oxime prevents hepatic I/R damage by inhibiting GSK-3beta and mitochondrial permeability transition.
Mitochondrion 2010;10(5):456-63.
2010: Rui A Carvalho; Rui P B Sousa; Virgilio J J Cadete; Gary D Lopaschuk; Carlos M Palmeira; James A Bjork; Kendall B Wallace
Metabolic remodeling associated with subchronic doxorubicin cardiomyopathy.
Toxicology 2010;270(2-3):92-8.
2010: Anabela Marques Simões; Filipe Valente Duarte; João Soeiro Teodoro; Anabela P Rolo; Carlos M Palmeira
Exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin and tetraethyl lead affects lung mitochondria bioenergetics.
Toxicology mechanisms and methods 2010;20(1):1-6.
2009: Anabela P Rolo; João Soeiro Teodoro; Carmen Peralta; Joan Rosello-Catafau; Carlos M Palmeira
Prevention of I/R injury in fatty livers by ischemic preconditioning is associated with increased mitochondrial tolerance: the key role of ATPsynthase and mitochondrial permeability transition.
Transplant international : official journal of the European Society for Organ Transplantation 2009;22(11):1081-90.
2009: Anabela P Rolo; Carlos M Palmeira; Gino A Cortopassi
Biosensor plates detect mitochondrial physiological regulators and mutations in vivo.
Analytical biochemistry 2009;385(1):176-8.
2008: Ana T Varela; Ana P Gomes; Anabela M Simões; João S Teodoro; Filipe V Duarte; Anabela P Rolo; Carlos M Palmeira
Indirubin-3'-oxime impairs mitochondrial oxidative phosphorylation and prevents mitochondrial permeability transition induction.
Toxicology and applied pharmacology 2008;233(2):179-85.
2008: João S Teodoro; Anabela P Rolo; Filipe V Duarte; Anabela M Simões; Carlos M Palmeira
Differential alterations in mitochondrial function induced by a choline-deficient diet: understanding fatty liver disease progression.
Mitochondrion 2008;8(5-6):367-76.
2007: Carlos M Palmeira; Anabela P Rolo; Jessica Berthiaume; James A Bjork; Kendall B Wallace
Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis.
Toxicology and applied pharmacology 2007;225(2):214-20.
2006: Anabela P Rolo; Carlos M Palmeira
Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress.
Toxicology and applied pharmacology 2006;212(2):167-78.
2006: João Teodoro; Anabela P Rolo; Paulo Oliveira; Carlos M Palmeira
Decreased ANT content in Zucker fatty rats: relevance for altered hepatic mitochondrial bioenergetics in steatosis.
FEBS letters 2006;580(8):2153-7.
2006: Fernanda M Ferreira; António J M Moreno; Raquel Seiça; Maria S Santos; Carlos M Palmeira
Mitochondrial Bioenergetics, Diabetes, and Aging: Top-Down Analysis Using the Diabetic Goto-Kakizaki (GK) Rat as a Model.
Toxicology mechanisms and methods 2006;16(6):323-30.
2005: Raquel Seiça; Dario Loureiro Santos; Carlos M Palmeira; António J M Moreno; Cristina Sena; Maria F Cunha; Maria S Santos
Mitochondrial function is not affected by renal morphological changes in diabetic goto-kakizaki rat.
Toxicology mechanisms and methods 2005;15(4):253-61.
2005: Manuela Ferreira; Pedro M Coxito; Vilma A Sardão; Carlos M Palmeira; Paulo Oliveira
Bile acids are toxic for isolated cardiac mitochondria: a possible cause for hepatic-derived cardiomyopathies?
Cardiovascular toxicology 2005;5(1):63-73.
2004: Carlos M Palmeira; Anabela P Rolo
Mitochondrially-mediated toxicity of bile acids.
Toxicology 2004;203(1-3):1-15.
2004: Paulo Oliveira; Anabela P Rolo; Vilma A Sardão; Pedro Monteiro; Lino Gonçalves; Luís A Providência; Carlos M Palmeira; António J M Moreno
Advantages in the use of carvedilol versus propranolol for the protection of cardiac mitochondrial function.
Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 2004;23(10):1291-8.
2004: Paulo Oliveira; Raquel Seica; Dario Loureiro Santos; Anabela P Rolo; Vilma A Sardao; Fernanda M Ferreira; Carlos M Palmeira; Maria S Santos; António J M Moreno
Vitamin E or coenzyme Q10 administration is not fully advantageous for heart mitochondrial function in diabetic goto kakizaki rats.
Mitochondrion 2004;3(6):337-45.
2004: Anabela P Rolo; Carlos M Palmeira; Jon Holy; Kendall B Wallace
Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis.
Toxicological sciences : an official journal of the Society of Toxicology 2004;79(1):196-204.
2004: Paulo Oliveira; Telma C Esteves; Anabela P Rolo; Carlos M Palmeira; António J M Moreno
Carvedilol inhibits the mitochondrial permeability transition by an antioxidant mechanism.
Cardiovascular toxicology 2004;4(1):11-20.
2003: Paulo Oliveira; Raquel Seiça; Pedro M Coxito; Anabela P Rolo; Carlos M Palmeira; Maria S Santos; António J M Moreno
Enhanced permeability transition explains the reduced calcium uptake in cardiac mitochondria from streptozotocin-induced diabetic rats.
FEBS letters 2003;554(3):511-4.
2003: Fernanda M Ferreira; Raquel Seiça; Paulo Oliveira; Pedro M Coxito; António J M Moreno; Carlos M Palmeira; Maria S Santos
Diabetes induces metabolic adaptations in rat liver mitochondria: role of coenzyme Q and cardiolipin contents.
Biochimica et biophysica acta 2003;1639(2):113-20.
2003: Carlos M Palmeira; Fernanda M Ferreira; Anabela P Rolo; Paulo Oliveira; Maria S Santos; António J M Moreno; Maria A Cipriano; Maria I Martins; Raquel Seiça
Histological changes and impairment of liver mitochondrial bioenergetics after long-term treatment with alpha-naphthyl-isothiocyanate (ANIT).
Toxicology 2003;190(3):185-96.
2003: Dario Loureiro Santos; Carlos M Palmeira; Raquel Seiça; José Dias; José Mesquita; António J M Moreno; Maria S Santos
Diabetes and mitochondrial oxidative stress: a study using heart mitochondria from the diabetic Goto-Kakizaki rat.
Molecular and cellular biochemistry 2003;246(1-2):163-70.
2003: Fernanda M Ferreira; Paulo Oliveira; Anabela P Rolo; Maria S Santos; António J M Moreno; M F da Cunha; Raquel Seiça; Carlos M Palmeira
Cholestasis induced by chronic treatment with alpha-naphthyl-isothiocyanate (ANIT) affects rat renal mitochondrial bioenergetics.
Archives of toxicology 2003;77(4):194-200.
2003: Anabela P Rolo; Paulo Oliveira; António J M Moreno; Carlos M Palmeira
Chenodeoxycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: protective role of carvedilol.
Mitochondrion 2003;2(4):305-11.
2003: Paulo Oliveira; Anabela P Rolo; Raquel Seiça; Maria S Santos; Carlos M Palmeira; António J M Moreno
Cardiac mitochondrial calcium loading capacity is severely affected after chronic cholestasis in Wistar rats.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2003;51(2):86-94.
2003: Anabela P Rolo; Carlos M Palmeira; Kendall B Wallace
Mitochondrially mediated synergistic cell killing by bile acids.
Biochimica et biophysica acta 2003;1637(1):127-32.
2003: Paulo Oliveira; Anabela P Rolo; Raquel Seiça; Maria S Santos; Carlos M Palmeira; António J M Moreno
Reduction in cardiac mitochondrial calcium loading capacity is observable during alpha-naphthylisothiocyanate-induced acute cholestasis: a clue for hepatic-derived cardiomyopathies?
Biochimica et biophysica acta 2003;1637(1):39-45.
2003: Fernanda M Ferreira; Carlos M Palmeira; Raquel Seiça; António J M Moreno; Maria S Santos
Diabetes and mitochondrial bioenergetics: alterations with age.
Journal of biochemical and molecular toxicology 2003;17(4):214-22.
2003: Paulo Oliveira; Anabela P Rolo; Raquel Seiça; Maria S Santos; Carlos M Palmeira; António J M Moreno
Chronic cholestasis and cardiac mitochondrial function in Wistar rats: a model for cardiovascular alterations in chronic liver disease?
Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 2003;22(1):67-75.
2003: Paulo Oliveira; Telma C Esteves; Anabela P Rolo; Pedro Monteiro; Lino Gonçalves; Carlos M Palmeira; António J M Moreno
Carvedilol: relation between antioxidant activity and inhibition of the mitochondrial permeability transition.
Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 2003;22(1):55-62.
2002: Paulo Oliveira; Anabela P Rolo; Pedro Monteiro; Lino Gonçalves; Carlos M Palmeira; António J M Moreno
Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase--what role in myocardial ischemia and reperfusion?
Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 2002;21(12):1447-55.
2002: Anabela P Rolo; Paulo Oliveira; Raquel Seiça; Maria S Santos; António J M Moreno; Carlos M Palmeira
Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of alpha-naphthylisothiocyanate.
Toxicology and applied pharmacology 2002;182(1):20-6.
2002: Paulo Oliveira; Anabela P Rolo; Raquel Seiça; Vilma A Sardão; Pedro Monteiro; Lino Gonçalves; Luís A Providência; Carlos M Palmeira; Maria S Santos; António J M Moreno
Impact of diabetes on induction of the mitochondrial permeability transition.
Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 2002;21(6):759-66.
2002: Anabela P Rolo; Paulo Oliveira; Raquel Seiça; Maria S Santos; António J M Moreno; Carlos M Palmeira
Disruption of mitochondrial calcium homeostasis after chronic alpha-naphthylisothiocyanate administration: relevance for cholestasis.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2002;50(3):193-200.
2002: Anabela P Rolo; Carlos M Palmeira; Kendall B Wallace
Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism.
Toxicology letters 2002;126(3):197-203.
2001: Carlos M Palmeira; Dario Loureiro Santos; Raquel Seiça; António J M Moreno; Maria S Santos
Enhanced mitochondrial testicular antioxidant capacity in Goto-Kakizaki diabetic rats: role of coenzyme Q.
American journal of physiology. Cell physiology 2001;281(3):C1023-8.
2001: Paulo Oliveira; Anabela P Rolo; Vilma A Sardão; Pedro M Coxito; Carlos M Palmeira; António J M Moreno
Carvedilol in heart mitochondria: protonophore or opener of the mitochondrial K(ATP) channels?
Life sciences 2001;69(2):123-32.
2001: Anabela P Rolo; Paulo Oliveira; António J M Moreno; Carlos M Palmeira
Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore.
Biochemical pharmacology 2001;61(11):1449-54.
2001: S Zhou; Carlos M Palmeira; Kendall B Wallace
Doxorubicin-induced persistent oxidative stress to cardiac myocytes.
Toxicology letters 2001;121(3):151-7.
2001: Maria S Santos; Dario Loureiro Santos; Carlos M Palmeira; Raquel Seiça; António J M Moreno; Catarina R Oliveira
Brain and liver mitochondria isolated from diabetic Goto-Kakizaki rats show different susceptibility to induced oxidative stress.
Diabetes/metabolism research and reviews 2001;17(3):223-30.
2001: Paulo Oliveira; Pedro M Coxito; Anabela P Rolo; Dario Loureiro Santos; Carlos M Palmeira; António J M Moreno
Inhibitory effect of carvedilol in the high-conductance state of the mitochondrial permeability transition pore.
European journal of pharmacology 2001;412(3):231-7.
2001: Anabela P Rolo; Paulo Oliveira; António J M Moreno; Carlos M Palmeira
Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria.
Bioscience reports 2001;21(1):73-80.
2001: Paulo Oliveira; Anabela P Rolo; Raquel Seiça; Carlos M Palmeira; Maria S Santos; António J M Moreno
Decreased susceptibility of heart mitochondria from diabetic GK rats to mitochondrial permeability transition induced by calcium phosphate.
Bioscience reports 2001;21(1):45-53.
2001: Paulo Oliveira; Anabela P Rolo; Carlos M Palmeira; António J M Moreno
Carvedilol reduces mitochondrial damage induced by hypoxanthine/xanthine oxidase: relevance to hypoxia/reoxygenation injury.
Cardiovascular toxicology 2001;1(3):205-13.
2000: Anabela P Rolo; Paulo Oliveira; António J M Moreno; Carlos M Palmeira
Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy.
Toxicological sciences : an official journal of the Society of Toxicology 2000;57(1):177-85.
2000: Carlos M Palmeira; M I Rana; C B Frederick; Kendall B Wallace
Induction of the mitochondrial permeability transition in vitro by short-chain carboxylic acids.
Biochemical and biophysical research communications 2000;272(2):431-5.
1999: Fernanda M Ferreira; Raquel Seiça; Maria S Santos; Carlos M Palmeira
Age-related alterations in liver mitochondrial bioenergetics of diabetic Goto-Kakizaki rats.
Acta diabetologica 1999;36(4):173-7.
1999: Carlos M Palmeira; Fernanda M Ferreira; Dario Loureiro Santos; R Ceiça; K Suzuki; Maria S Santos
Higher efficiency of the liver phosphorylative system in diabetic Goto-Kakizaki (GK) rats.
FEBS letters 1999;458(2):103-6.
1999: Fernanda M Ferreira; Carlos M Palmeira; Raquel Seiça; Maria S Santos
Alterations of liver mitochondrial bioenergetics in diabetic Goto-Kakizaki rats.
Metabolism: clinical and experimental 1999;48(9):1115-9.
1999: J Serrano; Carlos M Palmeira; D W Kuehl; Kendall B Wallace
Cardioselective and cumulative oxidation of mitochondrial DNA following subchronic doxorubicin administration.
Biochimica et biophysica acta 1999;1411(1):201-5.
1999: Fernanda M Ferreira; Carlos M Palmeira; MJ Matos; Raquel Seiça; Maria S Santos
Decreased susceptibility to lipid peroxidation of Goto-Kakizaki rats: relationship to mitochondrial antioxidant capacity.
Life sciences 1999;65(10):1013-25.
1998: António J M Moreno; DJ Santos; Carlos M Palmeira
Ischemic heart disease: the role of mitochondria--carvedilol prevents lipid peroxidation of mitochondrial membranes.
Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 1998;17 Suppl 2():II63-77.
1998: J B Custodio; Carlos M Palmeira; António J M Moreno; Kendall B Wallace
Acrylic acid induces the glutathione-independent mitochondrial permeability transition in vitro.
Toxicological sciences : an official journal of the Society of Toxicology 1998;43(1):19-27.
1997: Carlos M Palmeira; J Serrano; D W Kuehl; Kendall B Wallace
Preferential oxidation of cardiac mitochondrial DNA following acute intoxication with doxorubicin.
Biochimica et biophysica acta 1997;1321(2):101-6.
1997: Carlos M Palmeira; Kendall B Wallace
Benzoquinone inhibits the voltage-dependent induction of the mitochondrial permeability transition caused by redox-cycling naphthoquinones.
Toxicology and applied pharmacology 1997;143(2):338-47.
1996: Carlos M Palmeira; António J M Moreno; Vítor M C Madeira; Kendall B Wallace
Continuous monitoring of mitochondrial membrane potential in hepatocyte cell suspensions.
Journal of pharmacological and toxicological methods 1996;35(1):35-43.
1996: J Serrano; Carlos M Palmeira; Kendall B Wallace; D W Kuehl
Determination of 8-hydroxydeoxyguanosine in biological tissue by liquid chromatography/electrospray ionization-mass spectrometry/mass spectrometry.
Rapid communications in mass spectrometry : RCM 1996;10(14):1789-91.
1995: Carlos M Palmeira; António J M Moreno; Vítor M C Madeira
Thiols metabolism is altered by the herbicides paraquat, dinoseb and 2,4-D: a study in isolated hepatocytes.
Toxicology letters 1995;81(2-3):115-23.
1995: Carlos M Palmeira; António J M Moreno; Vítor M C Madeira
Mitochondrial bioenergetics is affected by the herbicide paraquat.
Biochimica et biophysica acta 1995;1229(2):187-92.
1995: Carlos M Palmeira; António J M Moreno; Vítor M C Madeira
Effects of paraquat, dinoseb and 2,4-D on intracellular calcium and on vasopressin-induced calcium mobilization in isolated hepatocytes.
Archives of toxicology 1995;69(7):460-6.
1994: Carlos M Palmeira; António J M Moreno; Vítor M C Madeira
Interactions of herbicides 2,4-D and dinoseb with liver mitochondrial bioenergetics.
Toxicology and applied pharmacology 1994;127(1):50-7.
1994: Carlos M Palmeira; António J M Moreno; Vítor M C Madeira
Metabolic alterations in hepatocytes promoted by the herbicides paraquat, dinoseb and 2,4-D.
Archives of toxicology 1994;68(1):24-31.
1993: Carlos M Palmeira; Maria S Santos; Arsélio P Carvalho; Catarina R Oliveira
Membrane lipid peroxidation induces changes in gamma-[3H]aminobutyric acid transport and calcium uptake by synaptosomes.
Brain research 1993;609(1-2):117-23.
1992: Carlos M Palmeira; Catarina R Oliveira
Partitioning and membrane disordering effects of dopamine antagonists: influence of lipid peroxidation, temperature, and drug concentration.
Archives of biochemistry and biophysics 1992;295(1):161-71.