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Duojia Pan

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Publications

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Dominic P Del Re; Noritsugu Nakano; Hiroshi Nojima; Duojia Pan; Norikazu Yabuta; Takanobu Yamamoto; Yanfei Yang; Peiyong Zhai; Nailing Zhang; Jaeyeaon Cho; Junichi Sadoshima
Yes-associated protein isoform 1 (Yap1) promotes cardiomyocyte survival and growth to protect against myocardial ischemic injury.
Haibo Bai; Steven Bronk; Qian Chen; Toby Cornish; Mehtab Khan; Suresh K Nayar; Duojia Pan; James J Potter; Yang Xu; Nailing Zhang; Gianfranco Alpini; Robert A Anders
Yes-associated protein regulates the hepatic response after bile duct ligation.
Haibo Bai; Mariana F Gayyed; Mehtab Khan; Alison P Klein; Dora M Lam-Himlin; Suresh K Nayar; Duojia Pan; Yang Xu; Pedram Argani; Robert A Anders
Expression of Yes-associated protein modulates Survivin expression in primary liver malignancies.

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All Publications

2013: Dominic P Del Re; Noritsugu Nakano; Hiroshi Nojima; Duojia Pan; Norikazu Yabuta; Takanobu Yamamoto; Yanfei Yang; Peiyong Zhai; Nailing Zhang; Jaeyeaon Cho; Junichi Sadoshima
Yes-associated protein isoform 1 (Yap1) promotes cardiomyocyte survival and growth to protect against myocardial ischemic injury.
The Journal of biological chemistry 2013;288(6):3977-88.
2012: Haibo Bai; Steven Bronk; Qian Chen; Toby Cornish; Mehtab Khan; Suresh K Nayar; Duojia Pan; James J Potter; Yang Xu; Nailing Zhang; Gianfranco Alpini; Robert A Anders
Yes-associated protein regulates the hepatic response after bile duct ligation.
Hepatology (Baltimore, Md.) 2012;56(3):1097-107.
2012: Haibo Bai; Mariana F Gayyed; Mehtab Khan; Alison P Klein; Dora M Lam-Himlin; Suresh K Nayar; Duojia Pan; Yang Xu; Pedram Argani; Robert A Anders
Expression of Yes-associated protein modulates Survivin expression in primary liver malignancies.
Human pathology 2012;43(9):1376-85.
2012: Yi Liu-Chittenden; Joong Sup Shim; Robert A Anders; Qian Chen; Bo Huang; Se-Jin Lee; Jun O Liu; Duojia Pan
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP.
Genes & development 2012;26(12):1300-5.
2012: Michel Kalamarides; Alison C Lloyd; Debra A Mayes; Ludwine MESSIAEN; Helen Morrison; Kathryn North; Roger Packer; Duojia Pan; Maria T Acosta; Dusica Babovic-Vuksanovic; Olli Carpen; Karen Cichowski; Filippo Giancotti; Kim Hunter-Schaedle; David Ingram; Anat Stemmer-Rachamimov; Meena Upadhyaya; David Viskochil; Margret R Wallace; D Gareth Evans; C Oliver Hanemann; Nancy Ratner
Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting.
Acta neuropathologica 2012;123(3):369-80.
2012: Arnau Sebé-Pedrós; Yonggang Zheng; Iñaki Ruiz-Trillo; Duojia Pan
Premetazoan origin of the hippo signaling pathway.
Cell reports 2012;1(1):13-20.
2010: Jing Cai; Nailing Zhang; Yonggang Zheng; Roeland F de Wilde; Anirban Maitra; Duojia Pan
The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program.
Genes & development 2010;24(21):2383-8.
2010: Duojia Pan
The hippo signaling pathway in development and cancer.
Developmental cell 2010;19(4):491-505.
2010: Nailing Zhang; Haibo Bai; Karen K David; Jixin Dong; Yonggang Zheng; Jing Cai; Marco Giovannini; Pentao Liu; Robert A Anders; Duojia Pan
The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals.
Developmental cell 2010;19(1):27-38.
2010: Chen Ling; Yonggang Zheng; Feng Yin; Jianzhong Yu; Juan Huang; Yang Hong; Shian Wu; Duojia Pan
The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(23):10532-7.
2010: Wei Tian; Jianzhong Yu; Diana R Tomchick; Duojia Pan; Xuelian Luo
Structural and functional analysis of the YAP-binding domain of human TEAD2.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(16):7293-8.
2010: Jianzhong Yu; Yonggang Zheng; Jixin Dong; Stephen Klusza; Wu-Min Deng; Duojia Pan
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded.
Developmental cell 2010;18(2):288-99.
2009: Claudio Alarcón; Alexia-Ileana Zaromytidou; Qiaoran Xi; Sheng Gao; Jianzhong Yu; Sho Fujisawa; Afsar Barlas; Alexandria N Miller; Katia Manova-Todorova; Maria J Macias; Gopal Sapkota; Duojia Pan; Joan Massagué
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways.
Cell 2009;139(4):757-69.
2008: Angela A Steinhardt; Mariana F Gayyed; Alison P Klein; Jixin Dong; Anirban Maitra; Duojia Pan; Elizabeth Montgomery; Robert A Anders
Expression of Yes-associated protein in common solid tumors.
Human pathology 2008;39(11):1582-9.
2008: Shian Wu; Yi Liu; Yonggang Zheng; Jixin Dong; Duojia Pan
The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway.
Developmental cell 2008;14(3):388-98.
2007: Jixin Dong; Georg Feldmann; Jianbin Huang; Shian Wu; Nailing Zhang; Sarah A Comerford; Mariana F Gayyed; Robert A Anders; Anirban Maitra; Duojia Pan
Elucidation of a universal size-control mechanism in Drosophila and mammals.
Cell 2007;130(6):1120-33.
2007: Duojia Pan
Hippo signaling in organ size control.
Genes & development 2007;21(8):886-97.
2007: Feng Yin; Duojia Pan
Fat flies expanded the hippo pathway: a matter of size control.
Science's STKE : signal transduction knowledge environment 2007;2007(380):pe12.
2006: Dora M Lam-Himlin; JASON DANIELS; Mariana F Gayyed; Jixin Dong; Anirban Maitra; Duojia Pan; Elizabeth Montgomery; Robert A Anders
The hippo pathway in human upper gastrointestinal dysplasia and carcinoma: a novel oncogenic pathway.
International journal of gastrointestinal cancer 2006;37(4):103-9.
2006: Yong Zhang; Charles J Billington; Duojia Pan; Thomas P Neufeld
Drosophila target of rapamycin kinase functions as a multimer.
Genetics 2006;172(1):355-62.
2005: Jianbin Huang; Shian Wu; Jose Barrera; Krista Matthews; Duojia Pan
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP.
Cell 2005;122(3):421-34.
2005: Katherine D Cygnar; Xinsheng Gao; Duojia Pan; Thomas P Neufeld
The phosphatase subunit tap42 functions independently of target of rapamycin to regulate cell division and survival in Drosophila.
Genetics 2005;170(2):733-40.
2004: Jixin Dong; Duojia Pan
Tsc2 is not a critical target of Akt during normal Drosophila development.
Genes & development 2004;18(20):2479-84.
2004: Duojia Pan; Jixin Dong; Yong Zhang; Xinsheng Gao
Tuberous sclerosis complex: from Drosophila to human disease.
Trends in cell biology 2004;14(2):78-85.
2004: Duojia Pan
Size matters. Workshop on growth control in development and disease.
EMBO reports 2004;5(2):136-9.
2003: Shian Wu; Jianbin Huang; Jixin Dong; Duojia Pan
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts.
Cell 2003;114(4):445-56.
2003: Yong Zhang; Xinsheng Gao; Leslie J Saucedo; Binggen Ru; Bruce A Edgar; Duojia Pan
Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins.
Nature cell biology 2003;5(6):578-81.
2003: Leslie J Saucedo; Xinsheng Gao; Dominic A Chiarelli; Ling Li; Duojia Pan; Bruce A Edgar
Rheb promotes cell growth as a component of the insulin/TOR signalling network.
Nature cell biology 2003;5(6):566-71.
2002: Xinsheng Gao; Yong Zhang; Peter Arrazola; Okio Hino; Toshiyuki Kobayashi; Raymond S Yeung; Binggen Ru; Duojia Pan
Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling.
Nature cell biology 2002;4(9):699-704.
2001: X Gao; Duojia Pan
TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth.
Genes & development 2001;15(11):1383-92.
2000: Xinsheng Gao; T P Neufeld; Duojia Pan
Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways.
Developmental biology 2000;221(2):404-18.
2000: Jeff S. Mumm; Eric H Schroeter; Meera T Saxena; A Griesemer; X Tian; Duojia Pan; William Ray; Raphael Kopan
A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1.
Molecular cell 2000;5(2):197-206.
1997: Duojia Pan; Gerald M Rubin
Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis.
Cell 1997;90(2):271-80.
1996: D Fambrough; Duojia Pan; Gerald M Rubin; Corey S Goodman
The cell surface metalloprotease/disintegrin Kuzbanian is required for axonal extension in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):13233-8.
1996: J Rooke; Duojia Pan; Tian Xu; G M Rubin
KUZ, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis.
Science (New York, N.Y.) 1996;273(5279):1227-31.
1995: Duojia Pan; Gerald M Rubin
cAMP-dependent protein kinase and hedgehog act antagonistically in regulating decapentaplegic transcription in Drosophila imaginal discs.
Cell 1995;80(4):543-52.
1994: Duojia Pan; S A Valentine; Albert J Courey
The bipartite D. melanogaster twist promoter is reorganized in D. virilis.
Mechanisms of development 1994;46(1):41-53.
1992: Duojia Pan; Albert J Courey
The same dorsal binding site mediates both activation and repression in a context-dependent manner.
The EMBO journal 1992;11(5):1837-42.
1991: Duojia Pan; J D Huang; Albert J Courey
Functional analysis of the Drosophila twist promoter reveals a dorsal-binding ventral activator region.
Genes & development 1991;5(10):1892-901.