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Rolf Berge

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Chemicals & Drugs

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Oxidation-Reduction

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Lipid Metabolism

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Erik Oie; Pål Aukrust; Jan Otto Beitnes; Rolf K Berge; Pavol Bohov; Christen P Dahl; Thor Edvardsen; Thor Ueland; Arne Yndestad
Tetradecylthioacetic acid increases fat metabolism and improves cardiac function in experimental heart failure.
Hanne R Hagland; Julie Nikolaisen; Linn I H Nilsson; Rolf K Berge; Lena Burri; Karl Johan Tronstad
Induction of mitochondrial biogenesis and respiration is associated with mTOR regulation in hepatocytes of rats treated with the pan-PPAR activator tetradecylthioacetic acid (TTA).
Leena E Viiri; Robin Wait; Tina J Navin; Mauro Perretti; Ilkka Seppälä; Joseph Shalhoub; Nagore Astola; Shajna Begum; Rolf K Berge; Alun H Davies; ATHANASIOS DIDANGELOS; Ian J Franklin; Louise E Full; Terho Lehtimäki; Claudia Monaco
Smooth muscle cells in human atherosclerosis: proteomic profiling reveals differences in expression of Annexin A1 and mitochondrial proteins in carotid disease.

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2013: Erik Oie; Pål Aukrust; Jan Otto Beitnes; Rolf K Berge; Pavol Bohov; Christen P Dahl; Thor Edvardsen; Thor Ueland; Arne Yndestad
Tetradecylthioacetic acid increases fat metabolism and improves cardiac function in experimental heart failure.
Lipids 2013;48(2):139-54.
2013: Hanne R Hagland; Julie Nikolaisen; Linn I H Nilsson; Rolf K Berge; Lena Burri; Karl Johan Tronstad
Induction of mitochondrial biogenesis and respiration is associated with mTOR regulation in hepatocytes of rats treated with the pan-PPAR activator tetradecylthioacetic acid (TTA).
Biochemical and biophysical research communications 2013;430(2):573-8.
2013: Leena E Viiri; Robin Wait; Tina J Navin; Mauro Perretti; Ilkka Seppälä; Joseph Shalhoub; Nagore Astola; Shajna Begum; Rolf K Berge; Alun H Davies; ATHANASIOS DIDANGELOS; Ian J Franklin; Louise E Full; Terho Lehtimäki; Claudia Monaco
Smooth muscle cells in human atherosclerosis: proteomic profiling reveals differences in expression of Annexin A1 and mitochondrial proteins in carotid disease.
Journal of molecular and cellular cardiology 2013;54():65-72.
2013: Bodil Bjørndal; Daniel Cacabelos; Tore Grimstad; Trygve Hausken; Gülen Arslan Lied; Kim Nylund; Roald Omdal; Reinald Pamplona; Manuel Portero-Otin; Ole Gunnar Aasprong; Rolf K Berge
Tetradecylthioacetic acid attenuates inflammation and has antioxidative potential during experimental colitis in rats.
Digestive diseases and sciences 2013;58(1):97-106.
2012: Reidar J Pettersen; Svein Rotevatn; Mohamed Salem; Rolf K Berge; Pavol Bohov; Karel K J Kuiper; Terje H Larsen; Jan Erik Nordrehaug
Effects of local delivery of tetradecylthioacetic acid within the injured coronary vessel wall.
Scandinavian cardiovascular journal : SCJ 2012;46(6):366-73.
2012: Bodil Bjørndal; Pavol Bohov; Trond Brattelid; Lena Burri; Ottar Nygård; Jon Skorve; Natalya Filipchuk Vigerust; Rita Vik; Rolf K Berge
Krill powder increases liver lipid catabolism and reduces glucose mobilization in tumor necrosis factor-alpha transgenic mice fed a high-fat diet.
Metabolism: clinical and experimental 2012;61(10):1461-72.
2012: Bodil Bjørndal; Pavol Bohov; Lena Burri; Asbjørn Svardal; Hege Wergedahl; Rolf K Berge
Dietary supplementation of herring roe and milt enhances hepatic fatty acid catabolism in female mice transgenic for hTNFα.
European journal of nutrition 2012;51(6):741-53.
2012: Goran Jassim; Miguel López; Niclas Lunder; Silje Skrede; Vidar M Steen; María Jesús Vázquez; Antonio Vidal-Puig; Audun Osland Vik-Mo; Hege Wergedal; Rolf K Berge; Carlos Diéguez; Johan Fernø
Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat.
Psychopharmacology 2012;219(3):783-94.
2012: Heidi Borgeraas; Jutta Dierkes; Dennis W T Nilsen; Eva Ringdal Pedersen; Reinhard Seifert; Elin Strand; Per Magne Ueland; Eirik Rebnord Wilberg; Rolf K Berge; Pavol Bohov; Ottar Nygård
Omega-3 Status and the Relationship between Plasma Asymmetric Dimethylarginine and Risk of Myocardial Infarction in Patients with Suspected Coronary Artery Disease.
Cardiology research and practice 2012;2012():201742.
2012: Elin Strand; Asgaut Viste; Hege Wergedahl; Christ Berge; Kjetil Berge; Bodil Bjorndal; Pavol Bohov; Lena Burri; Bjørn J Christensen; Ottar Nygard; Rolf K Berge
Long-term treatment with the pan-PPAR agonist tetradecylthioacetic acid or fish oil is associated with increased cardiac content of n-3 fatty acids in rat.
Lipids in health and disease 2012;11():82.
2011: Lena Burri; Asbjørn Svardal; Hege Wergedahl; Kjetil Berge; Bodil Bjørndal; Pavol Bohov; Rolf K Berge
Tetradecylthioacetic acid increases hepatic mitochondrial β-oxidation and alters fatty acid composition in a mouse model of chronic inflammation.
Lipids 2011;46(8):679-89.
2011: Tore Morken; Jon Skorve; Rune J Ulvik; Pål Aukrust; Rolf K Berge; Pavol Bohov; John K Livden
Anti-inflammatory and hypolipidemic effects of the modified fatty acid tetradecylthioacetic acid in psoriasis--a pilot study.
Scandinavian journal of clinical and laboratory investigation 2011;71(4):269-73.
2011: Ahmed M Khalid; Anne D Hafstad; Terje S Larsen; David L Severson; Neoma Boardman; Martin Hagve; Rolf K Berge; Ellen Aasum
Cardioprotective effect of the PPAR ligand tetradecylthioacetic acid in type 2 diabetic mice.
American journal of physiology. Heart and circulatory physiology 2011;300(6):H2116-22.
2011: Yushma Bhurruth-Alcor; Therese Røst; Michael R Jorgensen; Christos Kontogiorgis; Jon Skorve; Robert G Cooper; Joseph M Sheridan; William D O Hamilton; Jonathan R Heal; Rolf K Berge; Andrew D Miller
Synthesis of novel PPARα/γ dual agonists as potential drugs for the treatment of the metabolic syndrome and diabetes type II designed using a new de novo design program PROTOBUILD.
Organic & biomolecular chemistry 2011;9(4):1169-88.
2011: Tore Grimstad; Rolf K Berge; Pavol Bohov; Jon Skorve; Lasse G Gøransson; Roald Omdal; Ole G Aasprong; Margaretha Haugen; Helle Margrete Meltzer; Trygve Hausken
Salmon diet in patients with active ulcerative colitis reduced the simple clinical colitis activity index and increased the anti-inflammatory fatty acid index--a pilot study.
Scandinavian journal of clinical and laboratory investigation 2011;71(1):68-73.
2011: Anne G Lundemo; Caroline H H Pettersen; Kjetil Berge; Rolf K Berge; Svanhild Arentz Schønberg
Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells--gene expression profiling implies endoplasmic reticulum stress.
Lipids in health and disease 2011;10():190.
2011: Bodil Bjørndal; Lena Burri; Vidar Staalesen; Jon Skorve; Rolf K Berge
Different adipose depots: their role in the development of metabolic syndrome and mitochondrial response to hypolipidemic agents.
Journal of obesity 2011;2011():490650.
2011: Simon N Dankel; Vidar Staalesen; Bodil Bjørndal; Rolf K Berge; Gunnar Mellgren; Lena Burri
Tissue-specific effects of bariatric surgery including mitochondrial function.
Journal of obesity 2011;2011():435245.
2010: Kristin Hamre; Bente E Torstensen; Amund Maage; Rune Waagbø; Rolf K Berge; Sissel Albrektsen
Effects of dietary lipid, vitamins and minerals on total amounts and redox status of glutathione and ubiquinone in tissues of Atlantic salmon (Salmo salar): a multivariate approach.
The British journal of nutrition 2010;104(7):980-8.
2010: Katarina Mariann Jørgensen; Hanne Solvang Felberg; Rolf K Berge; Astrid Laegreid; Berit Johansen
Platelet activating factor stimulates arachidonic acid release in differentiated keratinocytes via arachidonyl non-selective phospholipase A2.
Archives of dermatological research 2010;302(3):221-7.
2010: Yushma Bhurruth-Alcor; Therese H Rost; Michael R Jorgensen; Melanie Müller; Jon Skorve; Rolf K Berge; Andrew D Miller
Novel phospholipid analogues of pan-PPAR activator tetradecylthioacetic acid are more PPAR alpha selective.
Bioorganic & medicinal chemistry letters 2010;20(3):1252-5.
2010: Lena Burri; G Hege Thoresen; Rolf K Berge
The Role of PPARα Activation in Liver and Muscle.
PPAR research 2010;2010():.
2009: Andreas J Wensaas; Arild C Rustan; Merethe H Rokling-Andersen; R Caesar; Jørgen Jensen; Olav Kaalhus; B A Graff; Oddrun Anita Gudbrandsen; Rolf K Berge; Christian Andre Drevon
Dietary supplementation of tetradecylthioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed on high-fat diets.
Diabetes, obesity & metabolism 2009;11(11):1034-49.
2009: Therese H Røst; Line L Haugan Moi; Kjetil Berge; Bart Staels; Gunnar Mellgren; Rolf K Berge
A pan-PPAR ligand induces hepatic fatty acid oxidation in PPARalpha-/- mice possibly through PGC-1 mediated PPARdelta coactivation.
Biochimica et biophysica acta 2009;1791(11):1076-83.
2009: Oddrun A Gudbrandsen; Enrique Rodríguez; Hege Wergedahl; Sverre Mork; Janne E Reseland; Jon Skorve; Andreu Palou; Rolf K Berge
Trans-10, cis-12-conjugated linoleic acid reduces the hepatic triacylglycerol content and the leptin mRNA level in adipose tissue in obese Zucker fa/fa rats.
The British journal of nutrition 2009;102(6):803-15.
2009: Anne D Hafstad; Ahmed M Khalid; Martin Hagve; Trine Lund; Terje S Larsen; David L Severson; Kieran Clarke; Rolf K Berge; Ellen Aasum
Cardiac peroxisome proliferator-activated receptor-alpha activation causes increased fatty acid oxidation, reducing efficiency and post-ischaemic functional loss.
Cardiovascular research 2009;83(3):519-26.
2009: Oddrun Anita Gudbrandsen; Hege Wergedahl; Pavol Bohov; Rolf K Berge
The absorption, distribution and biological effects of a modified fatty acid in its free form and as an ethyl ester in rats.
Chemico-biological interactions 2009;179(2-3):227-32.
2009: Oddrun Anita Gudbrandsen; Hege Wergedahl; Rolf K Berge
A casein diet added isoflavone-enriched soy protein favorably affects biomarkers of steatohepatitis in obese Zucker rats.
Nutrition (Burbank, Los Angeles County, Calif.) 2009;25(5):574-80.
2009: Kristian Løvås; T H Røst; Jon Skorve; R J Ulvik; Oddrun Anita Gudbrandsen; Pavol Bohov; A J Wensaas; Arild C Rustan; Rolf K Berge; Eystein S Husebye
Tetradecylthioacetic acid attenuates dyslipidaemia in male patients with type 2 diabetes mellitus, possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidation.
Diabetes, obesity & metabolism 2009;11(4):304-14.
2009: Johan Fernø; Audun Osland Vik-Mo; Goran Jassim; Bjarte Håvik; Knut Erik Berge; Silje Skrede; Oddrun Anita Gudbrandsen; Jo Erling Riise Waage; Niclas Lunder; Sverre Mørk; Rolf K Berge; Hugo A Jørgensen; Vidar M Steen
Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver.
Psychopharmacology 2009;203(1):73-84.
2009: Michael R Jorgensen; Yushma Bhurruth-Alcor; Therese Røst; Pavol Bohov; Melanie Müller; Cristina Guisado; Kostas Kostarelos; Endre Dyrøy; Rolf K Berge; Andrew D Miller; Jon Skorve
Synthesis and analysis of novel glycerolipids for the treatment of metabolic syndrome.
Journal of medicinal chemistry 2009;52(4):1172-9.
2009: Hege Wergedahl; Oddrun Anita Gudbrandsen; Therese Halvorsen Røst; Rolf K Berge
Combination of fish oil and fish protein hydrolysate reduces the plasma cholesterol level with a concurrent increase in hepatic cholesterol level in high-fat-fed Wistar rats.
Nutrition (Burbank, Los Angeles County, Calif.) 2009;25(1):98-104.
2008: Liliana Monica Bivol; Michael Hultström; Oddrun A Gudbrandsen; Rolf K Berge; Bjarne M Iversen
Tetradecylthioacetic acid downregulates cyclooxygenase 2 in the renal cortex of two-kidney, one-clip hypertensive rats.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;295(6):R1866-73.
2008: Oddrun Anita Gudbrandsen; Hege Wergedahl; Bjørn Liaset; Marit Espe; Sverre Mork; Rolf K Berge
Dietary single cell protein reduces fatty liver in obese Zucker rats.
The British journal of nutrition 2008;100(4):776-85.
2008: Hege Wergedahl; Knut Erik Berge; Pavol Bohov; Karl Johan Tronstad; Lise Madsen; Rolf K Berge
Long term treatment with tetradecylthioacetic acid improves the antioxidant status in obese Zucker (fa/fa) rats.
Drug metabolism letters 2008;2(2):138-45.
2008: Reidar J Pettersen; Mohamed Salem; Jon Skorve; Rune J Ulvik; Rolf K Berge; Jan Erik Nordrehaug
Pharmacology and safety of tetradecylthioacetic acid (TTA): phase-1 study.
Journal of cardiovascular pharmacology 2008;51(4):410-7.
2008: Liliana Monica Bivol; Rolf K Berge; Bjarne M Iversen
Tetradecylthioacetic acid prevents the inflammatory response in two-kidney, one-clip hypertension.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;294(2):R438-47.
2008: Ellen Aasum; Ahmed Murtaz Khalid; Oddrun Anita Gudbrandsen; Ole-Jakob How; Rolf K Berge; Terje S Larsen
Fenofibrate modulates cardiac and hepatic metabolism and increases ischemic tolerance in diet-induced obese mice.
Journal of molecular and cellular cardiology 2008;44(1):201-9.
2007: Line R Jensen; Kjetil Berge; Tone F Bathen; Hege Wergedahl; Svanhild Schønberg; Anna Bofin; Rolf K Berge; Ingrid S Gribbestad
Effect of dietary tetradecylthioacetic acid on colon cancer growth studied by dynamic contrast enhanced MRI.
Cancer biology & therapy 2007;6(11):1810-6.
2007: Karel K J Kuiper; Mohamed Salem; Oddrun Anita Gudbrandsen; Ziad A Muna; Rolf K Berge; Jan Erik Nordrehaug
Dose-dependent coronary artery intimal thickening after local delivery of the anti-oxidant tetradecylthioacetic acid from stents.
Atherosclerosis 2007;195(1):e39-47.
2007: Liliana Monica Bivol; Rolf K Berge; Bjarne M Iversen
Differential effect of tetradecythioacetic acid on the renin-angiotensin system and blood pressure in SHR and 2-kidney, 1-clip hypertension.
American journal of physiology. Renal physiology 2007;293(3):F839-45.
2007: Tor Gjøen; Ellen Johanne Kleveland; Corina Moya-Falcón; Marianne K Frøystad; Anne Vegusdal; Erlend Hvattum; Rolf K Berge; Bente Ruyter
Effects of dietary thia fatty acids on lipid composition, morphology and macrophage function of Atlantic salmon (Salmo salar L.) kidney.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2007;148(1):103-11.
2007: K-A Rørvik; H Alne; M Gaarder; Bente Ruyter; N P Måseide; Jan V Jakobsen; Rolf K Berge; Trygve Sigholt; Magny S Thomassen
Does the capacity for energy utilization affect the survival of post-smolt Atlantic salmon, Salmo salar L., during natural outbreaks of infectious pancreatic necrosis?
Journal of fish diseases 2007;30(7):399-409.
2007: Endre Dyrøy; Therese H Røst; Reidar J Pettersen; Bente Halvorsen; Oddrun Anita Gudbrandsen; Thor Ueland; Ziad A Muna; Fredrik Müller; Jan Erik Nordrehaug; Pål Aukrust; Rolf K Berge
Tetradecylselenoacetic acid, a PPAR ligand with antioxidant, antiinflammatory, and hypolipidemic properties.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(3):628-34.
2006: Ellen Johanne Kleveland; Bente Ruyter; Anne Vegusdal; Hilde Sundvold; Rolf K Berge; Tor Gjøen
Effects of 3-thia fatty acids on expression of some lipid related genes in Atlantic salmon (Salmo salar L.).
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2006;145(2):239-48.
2006: Oddrun Anita Gudbrandsen; Therese Halvorsen Rost; Rolf K Berge
Causes and prevention of tamoxifen-induced accumulation of triacylglycerol in rat liver.
Journal of lipid research 2006;47(10):2223-32.
2006: Oddrun Anita Gudbrandsen; Michael Hultstrøm; Sabine Leh; Liliana Monica Bivol; Øyvind B Vågnes; Rolf K Berge; Bjarne M Iversen
Prevention of hypertension and organ damage in 2-kidney, 1-clip rats by tetradecylthioacetic acid.
Hypertension 2006;48(3):460-6.
2006: Oddrun Anita Gudbrandsen; Hege Wergedahl; Sverre Mork; Bjørn Liaset; Marit Espe; Rolf K Berge
Dietary soya protein concentrate enriched with isoflavones reduced fatty liver, increased hepatic fatty acid oxidation and decreased the hepatic mRNA level of VLDL receptor in obese Zucker rats.
The British journal of nutrition 2006;96(2):249-57.
2006: Per Ole Iversen; Dag R Sørensen; Karl Johan Tronstad; Oddrun Anita Gudbrandsen; Arild C Rustan; Rolf K Berge; Christian Andre Drevon
A bioactively modified fatty acid improves survival and impairs metastasis in preclinical models of acute leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(11 Pt 1):3525-31.
2006: Endre Dyroy; Hege Wergedahl; Jon Skorve; Oddrun Anita Gudbrandsen; Jon Songstad; Rolf K Berge
Thia fatty acids with the sulfur atom in even or odd positions have opposite effects on fatty acid catabolism.
Lipids 2006;41(2):169-77.
2005: Kari Erichsen; Rune J Ulvik; T Grimstad; Arnold Berstad; Rolf K Berge; Trygve Hausken
Effects of ferrous sulphate and non-ionic iron-polymaltose complex on markers of oxidative tissue damage in patients with inflammatory bowel disease.
Alimentary pharmacology & therapeutics 2005;22(9):831-8.
2005: Oddrun Anita Gudbrandsen; Hege Wergedahl; Bjørn Liaset; Marit Espe; Rolf K Berge
Dietary proteins with high isoflavone content or low methionine-glycine and lysine-arginine ratios are hypocholesterolaemic and lower the plasma homocysteine level in male Zucker fa/fa rats.
The British journal of nutrition 2005;94(3):321-30.
2005: Kari Erichsen; Rune J Ulvik; Gunnar Nysaeter; Jack Johansen; Jens Ostborg; Arnold Berstad; Rolf K Berge; Trygve Hausken
Oral ferrous fumarate or intravenous iron sucrose for patients with inflammatory bowel disease.
Scandinavian journal of gastroenterology 2005;40(9):1058-65.
2005: Maria B Sandberg; Jakob Fridriksson; Lise Madsen; Vikas Rishi; Charles Vinson; Holm Holmsen; Rolf K Berge; Susanne Mandrup
Glucose-induced lipogenesis in pancreatic beta-cells is dependent on SREBP-1.
Molecular and cellular endocrinology 2005;240(1-2):94-106.
2005: Kari Erichsen; Anne Marita Milde; Gülen Arslan; Lars Helgeland; Oddrun Anita Gudbrandsen; Rune J Ulvik; Rolf K Berge; Trygve Hausken; Arnold Berstad
Low-dose oral ferrous fumarate aggravated intestinal inflammation in rats with DSS-induced colitis.
Inflammatory bowel diseases 2005;11(8):744-8.
2005: Endre Dyrøy; Arne Yndestad; Thor Ueland; Bente Halvorsen; Jan Kristian Damås; Pål Aukrust; Rolf K Berge
Antiinflammatory effects of tetradecylthioacetic acid involve both peroxisome proliferator-activated receptor alpha-dependent and -independent pathways.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(7):1364-9.
2005: Oddrun Anita Gudbrandsen; Endre Dyrøy; Pavol Bohov; Jon Skorve; Rolf K Berge
The metabolic effects of thia fatty acids in rat liver depend on the position of the sulfur atom.
Chemico-biological interactions 2005;155(1-2):71-81.
2005: Heidi Glosli; Oddrun Anita Gudbrandsen; Antony J Mullen; Bente Halvorsen; Therese H Røst; Hege Wergedahl; Hans Prydz; Pål Aukrust; Rolf K Berge
Down-regulated expression of PPARalpha target genes, reduced fatty acid oxidation and altered fatty acid composition in the liver of mice transgenic for hTNFalpha.
Biochimica et biophysica acta 2005;1734(3):235-46.
2005: Anne Vegusdal; Tor Gjøen; Rolf K Berge; Magny S Thomassen; Bente Ruyter
Effect of 18:1n-9, 20:5n-3, and 22:6n-3 on lipid accumulation and secretion by Atlantic salmon hepatocytes.
Lipids 2005;40(5):477-86.
2005: Johan Fernø; Maria Baroy Raeder; Audun Osland Vik-Mo; S Skrede; M Glambek; Karl Johan Tronstad; Harald Breilid; Roger Løvlie; Rolf K Berge; Christine Stansberg; Vidar M Steen
Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?
The pharmacogenomics journal 2005;5(5):298-304.
2005: Rolf K Berge; Karl Johan Tronstad; Knut Erik Berge; T H Rost; Hege Wergedahl; Oddrun Anita Gudbrandsen; Jon Skorve
The metabolic syndrome and the hepatic fatty acid drainage hypothesis.
Biochimie 2005;87(1):15-20.
2004: Corina Moya-Falcón; Erlend Hvattum; Endre Dyrøy; Jon Skorve; Sigurd O Stefansson; Magny S Thomassen; Jan V Jakobsen; Rolf K Berge; Bente Ruyter
Effects of 3-thia fatty acids on feed intake, growth, tissue fatty acid composition, beta-oxidation and Na+,K+-ATPase activity in Atlantic salmon.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2004;139(4):657-68.
2004: J Fredriksen; Thor Ueland; Endre Dyrøy; Bente Halvorsen; K Melby; L Melbye; B S Skalhegg; Pavol Bohov; Jon Skorve; Rolf K Berge; Pål Aukrust; Stig S Frøland
Lipid-lowering and anti-inflammatory effects of tetradecylthioacetic acid in HIV-infected patients on highly active antiretroviral therapy.
European journal of clinical investigation 2004;34(10):709-15.
2004: Hege Wergedahl; Bjørn Liaset; Oddrun Anita Gudbrandsen; Einar Lied; Marit Espe; Ziad A Muna; Sverre Mork; Rolf K Berge
Fish protein hydrolysate reduces plasma total cholesterol, increases the proportion of HDL cholesterol, and lowers acyl-CoA:cholesterol acyltransferase activity in liver of Zucker rats.
The Journal of nutrition 2004;134(6):1320-7.
2003: Rasmus K Petersen; Claus Jørgensen; Arild C Rustan; Livar Frøyland; Karin Muller-Decker; Gerhard Furstenberger; Rolf K Berge; Karsten Kristiansen; Lise Madsen
Arachidonic acid-dependent inhibition of adipocyte differentiation requires PKA activity and is associated with sustained expression of cyclooxygenases.
Journal of lipid research 2003;44(12):2320-30.
2003: Lise Madsen; Rasmus K Petersen; Morten B Sørensen; Claus Jørgensen; Philip Hallenborg; Lone Pridal; Jan Fleckner; Ez-Zoubir Amri; Peter Krieg; Gerhard Furstenberger; Rolf K Berge; Karsten Kristiansen
Adipocyte differentiation of 3T3-L1 preadipocytes is dependent on lipoxygenase activity during the initial stages of the differentiation process.
The Biochemical journal 2003;375(Pt 3):539-49.
2003: Karl Johan Tronstad; Knut Erik Berge; Rolf K Berge; Øystein Bruserud
Modified fatty acids and their possible therapeutic targets in malignant diseases.
Expert opinion on therapeutic targets 2003;7(5):663-77.
2003: Hans J Grav; Karl Johan Tronstad; Oddrun Anita Gudbrandsen; Knut Erik Berge; Kari E Fladmark; Tom C Martinsen; Helge L Waldum; Hege Wergedahl; Rolf K Berge
Changed energy state and increased mitochondrial beta-oxidation rate in liver of rats associated with lowered proton electrochemical potential and stimulated uncoupling protein 2 (UCP-2) expression: evidence for peroxisome proliferator-activated receptor-alpha independent induction of UCP-2 expression.
The Journal of biological chemistry 2003;278(33):30525-33.
2003: Pål Aukrust; Fredrik Müller; Asbjørn Svardal; Thor Ueland; Rolf K Berge; Stig S Frøland
Disturbed glutathione metabolism and decreased antioxidant levels in human immunodeficiency virus-infected patients during highly active antiretroviral therapy--potential immunomodulatory effects of antioxidants.
The Journal of infectious diseases 2003;188(2):232-8.
2003: Karl Johan Tronstad; Bjorn T Gjertsen; Camilla Krakstad; Knut Erik Berge; Odd T Brustugun; Stein Ove Døskeland; Rolf K Berge
Mitochondrial-targeted fatty acid analog induces apoptosis with selective loss of mitochondrial glutathione in promyelocytic leukemia cells.
Chemistry & biology 2003;10(7):609-18.
2003: Tesfaye Madebo; Bernt Lindtjorn; Pål Aukrust; Rolf K Berge
Circulating antioxidants and lipid peroxidation products in untreated tuberculosis patients in Ethiopia.
The American journal of clinical nutrition 2003;78(1):117-22.
2003: Kari Erichsen; Trygve Hausken; Rune J Ulvik; Asbjørn Svardal; Arnold Berstad; Rolf K Berge
Ferrous fumarate deteriorated plasma antioxidant status in patients with Crohn disease.
Scandinavian journal of gastroenterology 2003;38(5):543-8.
2003: Pål Aukrust; Hege Wergedahl; Fredrik Müller; Thor Ueland; Endre Dyrøy; Jan Kristian Damås; Stig S Frøland; Rolf K Berge
Immunomodulating effects of 3-thia fatty acids in activated peripheral blood mononuclear cells.
European journal of clinical investigation 2003;33(5):426-33.
2003: Rune Waagbø; Kristin Hamre; E Bjerkås; Rolf K Berge; E Wathne; O Lie; Bente E Torstensen
Cataract formation in Atlantic salmon, Salmo salar L., smolt relative to dietary pro- and antioxidants and lipid level.
Journal of fish diseases 2003;26(4):213-29.
2003: Knut Erik Berge; Karl Johan Tronstad; Pavol Bohov; Lise Madsen; Rolf K Berge
Impact of mitochondrial beta-oxidation in fatty acid-mediated inhibition of glioma cell proliferation.
Journal of lipid research 2003;44(1):118-27.
2002: Karl Johan Tronstad; Øystein Bruserud; Knut Erik Berge; Rolf K Berge
Antiproliferative effects of a non-beta-oxidizable fatty acid, tetradecylthioacetic acid, in native human acute myelogenous leukemia blast cultures.
Leukemia 2002;16(11):2292-301.
2002: Bodil Bjørndal; Charlotte Helleland; Stig Ove Bøe; Oddrun Anita Gudbrandsen; Karl-Henning Kalland; Pavol Bohov; Rolf K Berge; Johan R Lillehaug
Nuclear import of factors involved in signaling is inhibited in C3H/10T1/2 cells treated with tetradecylthioacetic acid.
Journal of lipid research 2002;43(10):1630-40.
2002: Heidi Glosli; Karl Johan Tronstad; Hege Wergedal; Fredrik Müller; Asbjørn Svardal; Pål Aukrust; Rolf K Berge; Hans Prydz
Human TNF-alpha in transgenic mice induces differential changes in redox status and glutathione-regulating enzymes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(11):1450-2.
2002: Rolf K Berge; Jon Skorve; Karl Johan Tronstad; Knut Erik Berge; Oddrun Anita Gudbrandsen; Hans J Grav
Metabolic effects of thia fatty acids.
Current opinion in lipidology 2002;13(3):295-304.
2002: Lise Madsen; Michèle Guerre-Millo; Esben N Flindt; Knut Erik Berge; Karl Johan Tronstad; Elin Bergene; Elena Sebokova; Arild C Rustan; Jørgen Jensen; Susanne Mandrup; Karsten Kristiansen; Iwar Klimes; Bart Staels; Rolf K Berge
Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance.
Journal of lipid research 2002;43(5):742-50.
2002: Ziad A Muna; Oddrun Anita Gudbrandsen; Hege Wergedahl; Pavol Bohov; Jon Skorve; Rolf K Berge
Inhibition of rat lipoprotein oxidation after tetradecylthioacetic acid feeding.
Biochemical pharmacology 2002;63(6):1127-35.
2001: Knut Erik Berge; Karl Johan Tronstad; Esben N Flindt; Tina H Rasmussen; Lise Madsen; Karsten Kristiansen; Rolf K Berge
Tetradecylthioacetic acid inhibits growth of rat glioma cells ex vivo and in vivo via PPAR-dependent and PPAR-independent pathways.
Carcinogenesis 2001;22(11):1747-55.
2001: Reidar J Pettersen; Ziad A Muna; Karel K J Kuiper; E Svendsen; Fredrik Müller; Pål Aukrust; Rolf K Berge; Jan Erik Nordrehaug
Sustained retention of tetradecylthioacetic acid after local delivery reduces angioplasty-induced coronary stenosis in the minipig.
Cardiovascular research 2001;52(2):306-13.
2001: Karel K J Kuiper; Ziad A Muna; Knut Ståle Erga; Endre Dyrøy; E Svendsen; Rolf K Berge; Jan Erik Nordrehaug
Tetradecylthioacetic acid reduces stenosis development after balloon angioplasty injury of rabbit iliac arteries.
Atherosclerosis 2001;158(2):269-75.
2001: Torbjørn Holm; Rolf K Berge; Arne K Andreassen; Thor Ueland; John Kjekshus; Svein Simonsen; Stig S Frøland; Lars Gullestad; Pål Aukrust
Omega-3 fatty acids enhance tumor necrosis factor-alpha levels in heart transplant recipients.
Transplantation 2001;72(4):706-11.
2001: Morten Elholm; I Dam; C Jorgensen; Anne-M Krogsdam; Dorte Holst; Irina Kratchmarova; M Gottlicher; J A Gustafsson; Rolf K Berge; Torgeir Flatmark; Jens Knudsen; Susanne Mandrup; Karsten Kristiansen
Acyl-CoA esters antagonize the effects of ligands on peroxisome proliferator-activated receptor alpha conformation, DNA binding, and interaction with Co-factors.
The Journal of biological chemistry 2001;276(24):21410-6.
2001: Majken Westergaard; Jeanette Henningsen; Morten Lyhne Svendsen; Claus Johansen; Uffe B Jensen; Henrik Daa Schrøder; Irina Kratchmarova; Rolf K Berge; Lars Iversen; Lars Bolund; Knud Kragballe; Karsten Kristiansen
Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid.
The Journal of investigative dermatology 2001;116(5):702-12.
2001: Karl Johan Tronstad; Knut Erik Berge; E Dyroy; Lise Madsen; Rolf K Berge
Growth reduction in glioma cells after treatment with tetradecylthioacetic acid: changes in fatty acid metabolism and oxidative status.
Biochemical pharmacology 2001;61(6):639-49.
2001: Reidar J Pettersen; Karel K J Kuiper; Livar Frøyland; Rolf K Berge; Jan Erik Nordrehaug
Long-term retention of a novel antioxidant sulphur-substituted fatty acid analogue after local delivery in porcine coronary arteries.
Scandinavian cardiovascular journal : SCJ 2001;35(2):101-6.
2001: Karl Johan Tronstad; Knut Erik Berge; Esben N Flindt; Karsten Kristiansen; Rolf K Berge
Optimization of methods and treatment conditions for studying effects of fatty acids on cell growth.
Lipids 2001;36(3):305-13.
2001: Morten Elholm; Hanne Hollås; C Issalene; João Filipe Barroso; Rolf K Berge; Torgeir Flatmark
Transient up-regulation of liver mitochondrial thymidine kinase activity in proliferating mitochondria.
IUBMB life 2001;51(2):99-104.
2001: Bente Halvorsen; Arild C Rustan; Lise Madsen; Janne E Reseland; Rolf K Berge; P Sletnes; EN Christiansen
Effects of long-chain monounsaturated and n-3 fatty acids on fatty acid oxidation and lipid composition in rats.
Annals of nutrition & metabolism 2001;45(1):30-7.
2000: Fredrik Müller; Asbjørn Svardal; I Nordoy; Rolf K Berge; Pål Aukrust; Stig S Frøland
Virological and immunological effects of antioxidant treatment in patients with HIV infection.
European journal of clinical investigation 2000;30(10):905-14.
2000: Geir K Totland; Lise Madsen; Beate Klementsen; H Vaagenes; Harald Kryvi; Livar Frøyland; S Hexeberg; Rolf K Berge
Proliferation of mitochondria and gene expression of carnitine palmitoyltransferase and fatty acyl-CoA oxidase in rat skeletal muscle, heart and liver by hypolipidemic fatty acids.
Biology of the cell / under the auspices of the European Cell Biology Organization 2000;92(5):317-29.
2000: Ziad A Muna; B J Bolann; X Chen; Jon Songstad; Rolf K Berge
Tetradecylthioacetic acid and tetradecylselenoacetic acid inhibit lipid peroxidation and interact with superoxide radical.
Free radical biology & medicine 2000;28(7):1068-78.
2000: Morten Elholm; A Garras; Søren Neve; Ditte Tornehave; T B Lund; Jon Skorve; Torgeir Flatmark; Karsten Kristiansen; Rolf K Berge
Long-chain acyl-CoA esters and acyl-CoA binding protein are present in the nucleus of rat liver cells.
Journal of lipid research 2000;41(4):538-45.
2000: Pål Aukrust; Fredrik Müller; Thor Ueland; Asbjørn Svardal; Rolf K Berge; Stig S Frøland
Decreased vitamin A levels in common variable immunodeficiency: vitamin A supplementation in vivo enhances immunoglobulin production and downregulates inflammatory responses.
European journal of clinical investigation 2000;30(3):252-9.
2000: Kristin Hamre; Rolf K Berge; O Lie
Turnover of tocopherols in Atlantic salmon (Salmo salar, L.).
BioFactors (Oxford, England) 2000;11(1-2):15-7.
1999: Rolf K Berge; Lise Madsen; H Vaagenes; Karl Johan Tronstad; M Göttlicher; Arild C Rustan
In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacylglycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation.
The Biochemical journal 1999;343 Pt 1():191-7.
1999: H Vaagenes; Lise Madsen; Endre Dyrøy; Morten Elholm; A Stray-Pedersen; Livar Frøyland; O Lie; Rolf K Berge
Methylated eicosapentaenoic acid and tetradecylthioacetic acid: effects on fatty acid metabolism.
Biochemical pharmacology 1999;58(7):1133-43.
1999: Lise Madsen; Arild C Rustan; H Vaagenes; Knut Erik Berge; Endre Dyrøy; Rolf K Berge
Eicosapentaenoic and docosahexaenoic acid affect mitochondrial and peroxisomal fatty acid oxidation in relation to substrate preference.
Lipids 1999;34(9):951-63.
1999: Lise Madsen; A Garras; Guillermina Asins; Dolors Serra; Fausto G Hegardt; Rolf K Berge
Mitochondrial 3-hydroxy-3-methylglutaryl coenzyme A synthase and carnitine palmitoyltransferase II as potential control sites for ketogenesis during mitochondrion and peroxisome proliferation.
Biochemical pharmacology 1999;57(9):1011-9.
1999: Lise Madsen; Rolf K Berge
3-Thia fatty acid treatment, in contrast to eicosapentaenoic acid and starvation, induces gene expression of carnitine palmitoyltransferase-II in rat liver.
Lipids 1999;34(5):447-56.
1999: Lise Madsen; Endre Dyrøy; Rolf K Berge
EPA and DHA possess different metabolic properties.
Advances in experimental medicine and biology 1999;466():315-20.
1999: Endre Dyrøy; Lise Madsen; Rolf K Berge
The effect of beta-oxidable and non-beta-oxidable thia fatty acids on fatty acid metabolism.
Advances in experimental medicine and biology 1999;466():311-4.
1999: H Vaagenes; Lise Madsen; Endre Dyrøy; Livar Frøyland; N Willumsen; Rolf K Berge
The hypolipidaemic effect of EPA is potentiated by 2- and 3-methylation.
Advances in experimental medicine and biology 1999;466():221-6.
1999: Knut Erik Berge; Karl Johan Tronstad; F Abdi-Dezfuli; T Ranheim; Rupavathana Mahesparan; Rolf Bjerkvig; Rolf K Berge
Poorly oxidizable fatty acid analogues inhibit the proliferation of cancer cells in culture.
Advances in experimental medicine and biology 1999;466():205-10.
1999: Karl Johan Tronstad; Knut Erik Berge; Rolf Bjerkvig; Torgeir Flatmark; Rolf K Berge
Metabolic effects of 3-thia fatty acid in cancer cells.
Advances in experimental medicine and biology 1999;466():201-4.
1999: Rolf K Berge; Lise Madsen; H Vaagenes
Hypolipidemic 3-thia fatty acids. Fatty acid oxidation and ketogenesis in rat liver under proliferation of mitochondria and peroxisomes.
Advances in experimental medicine and biology 1999;466():125-32.
1999: Endre Dyrøy; K J Kuiper; Reidar J Pettersen; Jan Erik Nordrehaug; Rolf K Berge
The influence of a novel antioxidant fatty acid on the development of stenosis after balloon injury.
Lipids 1999;34 Suppl():S339.
1999: Rolf K Berge; Lise Madsen; Livar Frøyland
The 3-thia fatty acid, a novel bioactive compound, which changes the plasma profile from atherogenic to cardioprotective.
Lipids 1999;34 Suppl():S201.
1999: Lise Madsen; Livar Frøyland; Harald Kryvi; J Auwerx; Bart Staels; Rolf K Berge
The mitochondrion is the principal target for nutritional and pharmacological control of plasma triglyceride.
Lipids 1999;34 Suppl():S167.
1999: Rolf K Berge; A Garras; Guillermina Asins; Dolors Serra; Fausto G Hegardt; Lise Madsen
Mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase and carnitine palmitoyltransferase II are potential control sites of hepatic ketogenesis under conditions of peroxisome proliferation.
Lipids 1999;34 Suppl():S163.
1998: H Vaagenes; Lise Madsen; D K Asiedu; Johan R Lillehaug; Rolf K Berge
Early modulation of genes encoding peroxisomal and mitochondrial beta-oxidation enzymes by 3-thia fatty acids.
Biochemical pharmacology 1998;56(12):1571-82.
1998: H Vaagenes; Ziad A Muna; Lise Madsen; Rolf K Berge
Low doses of eicosapentaenoic acid, docosahexaenoic acid, and hypolipidemic eicosapentaenoic acid derivatives have no effect on lipid peroxidation in plasma.
Lipids 1998;33(11):1131-7.
1998: John-Bjarne Hansen; Rolf K Berge; Arne Nordøy; Kaare H Bønaa
Lipid peroxidation of isolated chylomicrons and oxidative status in plasma after intake of highly purified eicosapentaenoic or docosahexaenoic acids.
Lipids 1998;33(11):1123-9.
1998: Livar Frøyland; Lise Madsen; K M Eckhoff; O Lie; Rolf K Berge
Carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, and acyl-CoA oxidase activities in Atlantic salmon (Salmo salar).
Lipids 1998;33(9):923-30.
1998: T Fiskerstrand; B Riedel; Per Magne Ueland; B Seetharam; E H Pezacka; S Gulati; Santanu Bose; R Banerjee; Rolf K Berge; Helga Refsum
Disruption of a regulatory system involving cobalamin distribution and function in a methionine-dependent human glioma cell line.
The Journal of biological chemistry 1998;273(32):20180-4.
1998: N Willumsen; H Vaagenes; Holm Holmsen; Rolf K Berge
On the effect of 2-deuterium- and 2-methyl-eicosapentaenoic acid derivatives on triglycerides, peroxisomal beta-oxidation and platelet aggregation in rats.
Biochimica et biophysica acta 1998;1369(2):193-203.
1998: Lise Madsen; Livar Frøyland; Endre Dyrøy; K Helland; Rolf K Berge
Docosahexaenoic and eicosapentaenoic acids are differently metabolized in rat liver during mitochondria and peroxisome proliferation.
Journal of lipid research 1998;39(3):583-93.
1998: Arne Nordøy; Kaare H Bønaa; Heidi Nilsen; Rolf K Berge; John-Bjarne Hansen; Ole Christian Ingebretsen
Effects of Simvastatin and omega-3 fatty acids on plasma lipoproteins and lipid peroxidation in patients with combined hyperlipidaemia.
Journal of internal medicine 1998;243(2):163-70.
1997: N Willumsen; H Vaagenes; Arild C Rustan; Hans J Grav; M Lundquist; Lars Skattebøl; Jon Songstad; Rolf K Berge
Enhanced hepatic fatty acid oxidation and upregulated carnitine palmitoyltransferase II gene expression by methyl 3-thiaoctadeca-6,9,12,15-tetraenoate in rats.
Journal of lipid mediators and cell signalling 1997;17(2):115-34.
1997: Ziad A Muna; K Doudin; Jon Songstad; R J Ulvik; Rolf K Berge
Tetradecylthioacetic acid inhibits the oxidative modification of low density lipoprotein and 8-hydroxydeoxyguanosine formation in vitro.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(11):3255-62.
1997: Charlotte Helleland; S A Eiane; Rolf K Berge; Holm Holmsen; Johan R Lillehaug
1-(Carboxymethylthio)tetradecane attenuates PDGF- and TPA-induced c-fos mRNA expression and increases the formation of phosphatidylethanolamine with a shift from less to more polar molecular species in C3H/10T1/2 cells.
Experimental cell research 1997;236(1):330-40.
1997: Livar Frøyland; H Vaagenes; D K Asiedu; A Garras; O Lie; Rolf K Berge
Hypotriacylglycerolemic component of fish oil.
Prostaglandins, leukotrienes, and essential fatty acids 1997;57(4-5):387-8.
1997: F Abdi-Dezfuli; Livar Frøyland; Thor Thorsen; A Aakvaag; Rolf K Berge
Eicosapentaenoic acid and sulphur substituted fatty acid analogues inhibit the proliferation of human breast cancer cells in culture.
Breast cancer research and treatment 1997;45(3):229-39.
1997: Pål Aukrust; Rolf K Berge; Fredrik Müller; Per Magne Ueland; Asbjørn Svardal; Stig S Frøland
Elevated plasma levels of reduced homocysteine in common variable immunodeficiency--a marker of enhanced oxidative stress.
European journal of clinical investigation 1997;27(9):723-30.
1997: Livar Frøyland; Lise Madsen; H Vaagenes; Geir K Totland; J Auwerx; Harald Kryvi; Bart Staels; Rolf K Berge
Mitochondrion is the principal target for nutritional and pharmacological control of triglyceride metabolism.
Journal of lipid research 1997;38(9):1851-8.
1997: Livar Frøyland; Lise Madsen; W Sjursen; A Garras; O Lie; Jon Songstad; Arild C Rustan; Rolf K Berge
Effect of 3-thia fatty acids on the lipid composition of rat liver, lipoproteins, and heart.
Journal of lipid research 1997;38(8):1522-34.
1997: A Garras; Morten Elholm; J Sleboda; Livar Frøyland; H Osmundsen; Rolf K Berge
On the effects of thia fatty acid analogues on hydrolases involved in the degradation of metabolisable and non-metabolisable acyl-CoA esters.
Xenobiotica; the fate of foreign compounds in biological systems 1997;27(8):781-99.
1997: Lise Madsen; Livar Frøyland; Hans J Grav; Rolf K Berge
Up-regulated delta 9-desaturase gene expression by hypolipidemic peroxisome-proliferating fatty acids results in increased oleic acid content in liver and VLDL: accumulation of a delta 9-desaturated metabolite of tetradecylthioacetic acid.
Journal of lipid research 1997;38(3):554-63.
1997: Kristin Hamre; Rune Waagbø; Rolf K Berge; O Lie
Vitamins C and E interact in juvenile Atlantic salmon (Salmo salar, L.).
Free radical biology & medicine 1997;22(1-2):137-49.
1996: H Brunvand; L Frłyland; E Hexeberg; S E Rynning; Rolf K Berge; Ketil Grong
Carvedilol improves function and reduces infarct size in the feline myocardium by protecting against lethal reperfusion injury.
European journal of pharmacology 1996;314(1-2):99-107.
1996: H Brunvand; P M Kvitting; S E Rynning; Rolf K Berge; Ketil Grong
Carvedilol protects against lethal reperfusion injury through antiadrenergic mechanisms.
Journal of cardiovascular pharmacology 1996;28(3):409-17.
1996: H Brunvand; Livar Frøyland; J Westby; E Hexeberg; Rolf K Berge; Ketil Grong
Peroxisomal fatty acid oxidation capacity is more resistant to ischaemic and reperfusion injury than mitochondrial fatty acid oxidation capacity in feline hearts.
Acta physiologica Scandinavica 1996;157(2):133-45.
1996: N Willumsen; H Vaagenes; O Lie; Arild C Rustan; Rolf K Berge
Eicosapentaenoic acid, but not docosahexaenoic acid, increases mitochondrial fatty acid oxidation and upregulates 2,4-dienoyl-CoA reductase gene expression in rats.
Lipids 1996;31(6):579-92.
1996: D K Asiedu; Livar Frøyland; H Vaagenes; O Lie; A Demoz; Rolf K Berge
Long-term effect of tetradecylthioacetic acid: a study on plasma lipid profile and fatty acid composition and oxidation in different rat organs.
Biochimica et biophysica acta 1996;1300(2):86-96.
1996: Livar Frøyland; H Vaagenes; D K Asiedu; A Garras; O Lie; Rolf K Berge
Chronic administration of eicosapentaenoic acid and docosahexaenoic acid as ethyl esters reduced plasma cholesterol and changed the fatty acid composition in rat blood and organs.
Lipids 1996;31(2):169-78.
1996: Livar Frøyland; K Helland; Geir K Totland; Harald Kryvi; Rolf K Berge
A hypolipidemic peroxisome proliferating fatty acid induces polydispersity of rat liver mitochondria.
Biology of the cell / under the auspices of the European Cell Biology Organization 1996;87(1-2):105-12.
1995: Livar Frøyland; D K Asiedu; H Vaagenes; A Garras; O Lie; Geir K Totland; Rolf K Berge
Tetradecylthioacetic acid incorporated into very low density lipoprotein: changes in the fatty acid composition and reduced plasma lipids in cholesterol-fed hamsters.
Journal of lipid research 1995;36(12):2529-40.
1995: J Skorve; J Rosendal; H Vaagenes; Jens Knudsen; Johan R Lillehaug; Rolf K Berge
Fatty acyl-CoA oxidase activity is induced before long-chain acyl-CoA hydrolase activity and acyl-CoA binding protein in liver of rat treated with peroxisome proliferating 3-thia fatty acids.
Xenobiotica; the fate of foreign compounds in biological systems 1995;25(11):1181-94.
1995: J Skorve; Arild C Rustan; Rolf K Berge
Effects of non-beta-oxidizable sulfur-substituted fatty acid analogues on synthesis and secretion of triacylglycerol and cholesterol in cultured rat hepatocytes.
Lipids 1995;30(11):987-94.
1995: S Hexeberg; Livar Frøyland; D K Asiedu; A Demoz; Rolf K Berge
Tetradecylthioacetic acid reduces the amount of lipid droplets, induces megamitochondria formation and increases the fatty acid oxidation in rat heart.
Journal of molecular and cellular cardiology 1995;27(9):1851-7.
1995: S Hexeberg; N Willumsen; Rolf K Berge
Eicosapentaenoic acid causes transient accumulation of lipids in rat myocardium.
Biochimica et biophysica acta 1995;1256(3):341-5.
1995: A Demoz; A Garras; D K Asiedu; B Netteland; Rolf K Berge
Rapid method for the separation and detection of tissue short-chain coenzyme A esters by reversed-phase high-performance liquid chromatography.
Journal of chromatography. B, Biomedical applications 1995;667(1):148-52.
1995: D K Asiedu; A Demoz; J Skorve; H J Grav; Rolf K Berge
Acute modulation of rat hepatic lipid metabolism by sulphur-substituted fatty acid analogues.
Biochemical pharmacology 1995;49(7):1013-22.
1995: A Garras; D K Asiedu; Rolf K Berge
Subcellular localisation and induction of NADH-sensitive acetyl-CoA hydrolase and propionyl-CoA hydrolase activities in rat liver under lipogenic conditions after treatment with sulfur-substituted fatty acids.
Biochimica et biophysica acta 1995;1255(2):154-60.
1995: A Gedde-Dahl; Trine Ranheim; Christian Andre Drevon; S Skrede; Rolf K Berge; Arild C Rustan
Tetradecylthioacetic acid (a 3-thia fatty acid) decreases triacylglycerol secretion in CaCo-2 cells.
Journal of lipid research 1995;36(3):535-43.
1995: D K Asiedu; Ayman Al-Shurbaji; Arild C Rustan; Ingemar Björkhem; Lars Berglund; Rolf K Berge
Hepatic fatty acid metabolism as a determinant of plasma and liver triacylglycerol levels. Studies on tetradecylthioacetic and tetradecylthiopropionic acids.
European journal of biochemistry / FEBS 1995;227(3):715-22.
1994: S Hexeberg; N Willumsen; Rolf K Berge
Docosahexaenoic acid induces lipid accumulation in myocardial cells of rats.
Scandinavian journal of clinical and laboratory investigation 1994;54(8):665-71.
1994: F Abdi-Dezfuli; Rolf K Berge; M Rasmussen; Thor Thorsen; A Aakvaag
Effects of saturated and polyunsaturated fatty acids and their 3-thia fatty acid analogues on MCF-7 breast cancer cell growth.
Annals of the New York Academy of Sciences 1994;744():306-9.
1994: H J Grav; D K Asiedu; Rolf K Berge
Gas chromatographic measurement of 3- and 4-thia fatty acids incorporated into various classes of rat liver lipids during feeding experiments.
Journal of chromatography. B, Biomedical applications 1994;658(1):1-10.
1994: K L Gearing; M Göttlicher; E Widmark; C D Banner; P Tollet; M Strömstedt; Joseph Rafter; Rolf K Berge; J A Gustafsson
Fatty acid activation of the peroxisome proliferator activated receptor, a member of the nuclear receptor gene superfamily.
The Journal of nutrition 1994;124(8 Suppl):1284S-1288S.
1994: S Skrede; Jon Bremer; Rolf K Berge; Arild C Rustan
Stimulation of fatty acid oxidation by a 3-thia fatty acid reduces triacylglycerol secretion in cultured rat hepatocytes.
Journal of lipid research 1994;35(8):1395-404.
1994: A Demoz; D K Asiedu; O Lie; Rolf K Berge
Modulation of plasma and hepatic oxidative status and changes in plasma lipid profile by n-3 (EPA and DHA), n-6 (corn oil) and a 3-thia fatty acid in rats.
Biochimica et biophysica acta 1994;1199(3):238-44.
1994: P Tollet; M Strömstedt; L Frøyland; Rolf K Berge; J A Gustafsson
Pretranslational regulation of cytochrome P4504A1 by free fatty acids in primary cultures of rat hepatocytes.
Journal of lipid research 1994;35(2):248-54.
1994: S Hexeberg; E Hexeberg; N Willumsen; Rolf K Berge
A study on lipid metabolism in heart and liver of cholesterol- and pectin-fed rats.
The British journal of nutrition 1994;71(2):181-92.
1994: J A Gustafsson; K Gearing; E Widmark; P Tollet; M Strömstedt; Rolf K Berge; M Göttlicher
Effects of fatty acids on gene expression mediated by a member of the nuclear receptor supergene family.
Progress in clinical and biological research 1994;387():21-8.
1994: Rolf K Berge; E Hvattum
Impact of cytochrome P450 system on lipoprotein metabolism. Effect of abnormal fatty acids (3-thia fatty acids).
Pharmacology & therapeutics 1994;61(3):345-83.
1993: M Göttlicher; A Demoz; D Svensson; P Tollet; Rolf K Berge; J A Gustafsson
Structural and metabolic requirements for activators of the peroxisome proliferator-activated receptor.
Biochemical pharmacology 1993;46(12):2177-84.
1993: Ayman Al-Shurbaji; J Skorve; Rolf K Berge; M Rudling; Ingemar Björkhem; Lars Berglund
Effect of 3-thiadicarboxylic acid on lipid metabolism in experimental nephrosis.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(11):1580-6.
1993: J Skorve; A M Svardal; M A Mansoor; Rolf K Berge
Modulation of phosphatidylcholine biosynthesis by peroxisome proliferating fatty acid analogues.
Lipids 1993;28(9):795-801.
1993: N Willumsen; J Skorve; S Hexeberg; Arild C Rustan; Rolf K Berge
The hypotriglyceridemic effect of eicosapentaenoic acid in rats is reflected in increased mitochondrial fatty acid oxidation followed by diminished lipogenesis.
Lipids 1993;28(8):683-90.
1993: J Skorve; Ayman Al-Shurbaji; D Asiedu; Ingemar Björkhem; Lars Berglund; Rolf K Berge
On the mechanism of the hypolipidemic effect of sulfur-substituted hexadecanedioic acid (3-thiadicarboxylic acid) in normolipidemic rats.
Journal of lipid research 1993;34(7):1177-85.
1993: J Skorve; Rolf K Berge
The hypocholesterolemic effect of sulfur-substituted fatty acid analogues in rats fed a high carbohydrate diet.
Biochimica et biophysica acta 1993;1167(2):175-81.
1993: S Hexeberg; N Willumsen; S Rotevatn; E Hexeberg; Rolf K Berge
Cholesterol induced lipid accumulation in myocardial cells of rats.
Cardiovascular research 1993;27(3):442-6.
1993: D K Asiedu; J Skorve; N Willumsen; A Demoz; Rolf K Berge
Early effects on mitochondrial and peroxisomal beta-oxidation by the hypolipidemic 3-thia-fatty acids in rat livers.
Biochimica et biophysica acta 1993;1166(1):73-6.
1993: A Demoz; A Svardal; Rolf K Berge
Relationship between peroxisome-proliferating sulfur-substituted fatty acid analogs, hepatic lipid peroxidation and hydrogen peroxide metabolism.
Biochemical pharmacology 1993;45(1):257-9.
1993: N Willumsen; S Hexeberg; J Skorve; M Lundquist; Rolf K Berge
Docosahexaenoic acid shows no triglyceride-lowering effects but increases the peroxisomal fatty acid oxidation in liver of rats.
Journal of lipid research 1993;34(1):13-22.
1992: A Demoz; N Willumsen; Rolf K Berge
Eicosapentaenoic acid at hypotriglyceridemic dose enhances the hepatic antioxidant defense in mice.
Lipids 1992;27(12):968-71.
1992: M Farstad; Anne M Bakken; Rolf K Berge
The activity and subcellular distribution of the peroxisomal enzyme acyl-CoA oxidase in human blood platelets.
The Biochemical journal 1992;286 ( Pt 3)():829-31.
1992: D Asiedu; J Skorve; A Demoz; N Willumsen; Rolf K Berge
Relationship between translocation of long-chain acyl-CoA hydrolase, phosphatidate phosphohydrolase and CTP:phosphocholine cytidylyltransferase and the synthesis of triglycerides and phosphatidylcholine in rat liver.
Lipids 1992;27(4):241-7.
1992: J Skorve; D Asiedu; M Solbakken; J Gjestdal; Jon Songstad; Rolf K Berge
Comparative effects of oxygen and sulfur-substituted fatty acids on serum lipids and mitochondrial and peroxisomal fatty acid oxidation in rat.
Biochemical pharmacology 1992;43(4):815-22.
1991: Erlend Hvattum; S Bergseth; C N Pedersen; Jon Bremer; A Aarsland; Rolf K Berge
Microsomal oxidation of dodecylthioacetic acid (a 3-thia fatty acid) in rat liver.
Biochemical pharmacology 1991;41(6-7):945-53.
1991: A Aarsland; Rolf K Berge
Peroxisome proliferating sulphur- and oxy-substituted fatty acid analogues are activated to acyl coenzyme A thioesters.
Biochemical pharmacology 1991;41(1):53-61.
1990: J Skorve; Bente Ruyter; Arild C Rustan; E N Christiansen; Christian Andre Drevon; Rolf K Berge
Effect of 3- and 4-thia-substituted fatty acids on glycerolipid metabolism and mitochondrial beta-oxidation in rat liver.
Biochemical pharmacology 1990;40(9):2005-12.
1990: A Aarsland; M Lundquist; B Børretsen; Rolf K Berge
On the effect of peroxisomal beta-oxidation and carnitine palmitoyltransferase activity by eicosapentaenoic acid in liver and heart from rats.
Lipids 1990;25(9):546-8.
1990: J Skorve; D Asiedu; Arild C Rustan; Christian Andre Drevon; Ayman Al-Shurbaji; Rolf K Berge
Regulation of fatty acid oxidation and triglyceride and phospholipid metabolism by hypolipidemic sulfur-substituted fatty acid analogues.
Journal of lipid research 1990;31(9):1627-35.
1990: R Hovik; Harald Osmundsen; Rolf K Berge; A Aarsland; S Bergseth; Jon Bremer
Effects of thia-substituted fatty acids on mitochondrial and peroxisomal beta-oxidation. Studies in vivo and in vitro.
The Biochemical journal 1990;270(1):167-73.
1990: D Asiedu; A Aarsland; J Skorve; A M Svardal; Rolf K Berge
Fatty acid metabolism in liver of rats treated with hypolipidemic sulphur-substituted fatty acid analogues.
Biochimica et biophysica acta 1990;1044(2):211-21.
1990: Harald Kryvi; A Aarsland; Rolf K Berge
Morphologic effects of sulfur-substituted fatty acids on rat hepatocytes with special reference to proliferation of peroxisomes and mitochondria.
Journal of structural biology 1990;103(3):257-65.
1990: A Aarsland; Rolf K Berge; Jon Bremer; N Aarsaether
The hypolipidemic peroxisome-proliferating drug, bis(carboxymethylthio)-1.10 decane, a dicarboxylic metabolite of tiadenol, is activated to an acylcoenzyme A thioester.
Biochimica et biophysica acta 1990;1033(2):176-83.
1990: N Aarsaether; R Fosse; A Aarsland; Rolf K Berge
Effects of the tumor promoter 12-O-tetradecanoylphorbol 13-acetate on peroxisomal activities and enzyme activities involved in lipid metabolism in rat liver.
Biochimica et biophysica acta 1990;1042(1):86-93.
1989: Rolf K Berge; A Aarsland; Harald Kryvi; Jon Bremer; N Aarsaether
Alkylthio acetic acids (3-thia fatty acids)--a new group of non-beta-oxidizable peroxisome-inducing fatty acid analogues--II. Dose-response studies on hepatic peroxisomal- and mitochondrial changes and long-chain fatty acid metabolizing enzymes in rats.
Biochemical pharmacology 1989;38(22):3969-79.
1989: A Aarsland; N Aarsaether; Jon Bremer; Rolf K Berge
Alkylthioacetic acids (3-thia fatty acids) as non-beta-oxidizable fatty acid analogues: a new group of hypolipidemic drugs. III. Dissociation of cholesterol- and triglyceride-lowering effects and the induction of peroxisomal beta-oxidation.
Journal of lipid research 1989;30(11):1711-8.
1989: Rolf K Berge; A Aarsland; Harald Kryvi; Jon Bremer; N Aarsaether
Alkylthioacetic acid (3-thia fatty acids)--a new group of non-beta-oxidizable, peroxisome-inducing fatty acid analogues. I. A study on the structural requirements for proliferation of peroxisomes and mitochondria in rat liver.
Biochimica et biophysica acta 1989;1004(3):345-56.
1989: N Aarsaether; A Aarsland; Harald Kryvi; A Nilsson; A Svardal; Per Magne Ueland; Rolf K Berge
Changes in peroxisomes and mitochondria in liver of ethionine exposed rats: a biochemical and morphological investigation.
Carcinogenesis 1989;10(6):987-94.
1988: N Aarsaether; Rolf K Berge; A M Husøy; A Aarsland; Harald Kryvi; A Svardal; Per Magne Ueland; M Farstad
Ethionine-induced alterations of enzymes involved in lipid metabolism and their possible relationship to induction of fatty liver.
Biochimica et biophysica acta 1988;963(2):349-58.
1988: Rolf K Berge; A Nilsson; A M Husøy
Rapid stimulation of liver palmitoyl-CoA synthetase, carnitine palmitoyltransferase and glycerophosphate acyltransferase compared to peroxisomal beta-oxidation and palmitoyl-CoA hydrolase in rats fed high-fat diets.
Biochimica et biophysica acta 1988;960(3):417-26.
1988: Rolf K Berge; N Aarsaether; A Aarsland; A Svardal; Per Magne Ueland
Effect of choline-deficiency and methotrexate administration on peroxisomal beta-oxidation, palmitoyl-CoA hydrolase activity and the glutathione content in rat liver.
Carcinogenesis 1988;9(4):619-24.
1988: A M Svardal; Per Magne Ueland; N Aarsaether; A Aarsland; Rolf K Berge
Differential metabolic response of rat liver, kidney and spleen to ethionine exposure. S-adenosylamino acids, homocysteine and reduced glutathione in tissues.
Carcinogenesis 1988;9(2):227-32.
1988: N Aarsaether; Rolf K Berge; A Aarsland; A Svardal; Per Magne Ueland
Effect of methotrexate on long-chain fatty acid metabolism in liver of rats fed a standard or a defined, choline-deficient diet.
Biochimica et biophysica acta 1988;958(1):70-80.
1988: A M Svardal; Per Magne Ueland; Rolf K Berge; A Aarsland; N Aarsaether; Per Eystein Lønning; Helga Refsum
Effect of methotrexate on homocysteine and other sulfur compounds in tissues of rats fed a normal or a defined, choline-deficient diet.
Cancer chemotherapy and pharmacology 1988;21(4):313-8.
1987: Rolf K Berge; E Stensland; A Aarsland; G Tsegai; Harald Osmundsen; N Aarsaether; Dag Rune Gjellesvik
Induction of cytosolic clofibroyl-CoA hydrolase activity in liver of rats treated with clofibrate.
Biochimica et biophysica acta 1987;918(1):60-6.
1986: T Lygre; N Aarsaether; E Stensland; A Aarsland; Rolf K Berge
Separation and measurement of clofibroyl coenzyme A and clofibric acid in rat liver after clofibrate adminstration by reversed-phase high-performance liquid chromatography with photodiode array detection.
Journal of chromatography 1986;381(1):95-105.
1986: Johan R Lillehaug; N Aarsaether; Rolf K Berge; R Male
Peroxisome proliferators show tumor-promoting but no direct transforming activity in vitro.
International journal of cancer. Journal international du cancer 1986;37(1):97-100.
1984: Rolf K Berge; L H Hosøy; A Aarsland; O M Bakke; M Farstad
Enzymatic changes in rat liver associated with low and high doses of a peroxisome proliferator.
Toxicology and applied pharmacology 1984;73(1):35-41.
1983: Rolf K Berge; Harald Osmundsen; A Aarsland; M Farstad
The existence of separate peroxisomal pools of free coenzyme a and long-chain acyl-CoA in rat liver, demonstrated by a specific high performance liquid chromatography method.
The International journal of biochemistry 1983;15(2):205-9.
1983: Rolf K Berge; A Aarsland; O M Bakke; M Farstad
Hepatic enzymes, CoASH and long-chain acyl-CoA in subcellular fractions as affected by drugs inducing peroxisomes and smooth endoplasmic reticulum.
The International journal of biochemistry 1983;15(2):191-204.