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Marie Pancera

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HIV-1

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Ivelin S Georgiev; Young Do Kwon; Han R Altae-Tran; Robert T Bailer; Gwo-Yu Chuang; Mark Connors; Nicole A Doria-Rose; Mark K Louder; Malcolm A Martin; John R Mascola; Krisha McKee; Stephen A Migueles; Stephanie Moquin; Lynn Morris; Martha Nason; Yoshiaki Nishimura; Sijy O'Dell; Gilad Ofek; Marie Pancera; Stephen D Schmidt; Lawrence Shapiro; Sanjay Srivatsan; Ryan P Staupe; Tongqing Zhou; Peter D Kwong
Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.
Jiang Zhu; S Munir Alam; Julie Blinn; Dennis R Burton; Joshua Eudailey; Barton F Haynes; Wayne C Koff; Krissey E Lloyd; Mark K Louder; Gabriel Lu; John R Mascola; Krisha McKee; James C Mullikin; Gilad Ofek; Marie Pancera; Robert Parks; Lawrence Shapiro; Melissa Simek; Jeff Skinner; Yongping Yang; Baoshan Zhang; Zhenhai Zhang; Peter D Kwong
Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains.
Florian Klein; Peter D Kwong; Hugo Mouquet; Pamela J Bjorkman; Ron Diskin; Brooks Zhongzheng Fu; Christian Gaebler; Ivelin S Georgiev; Priyanthi N P Gnanapragasam; Reha-Baris Incesu; Thiago Y Oliveira; Marie Pancera; Johannes F Scheid; Michael S Seaman; Tongqing Zhou; Michel C Nussenzweig
Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization.

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All Publications

2013: Ivelin S Georgiev; Young Do Kwon; Han R Altae-Tran; Robert T Bailer; Gwo-Yu Chuang; Mark Connors; Nicole A Doria-Rose; Mark K Louder; Malcolm A Martin; John R Mascola; Krisha McKee; Stephen A Migueles; Stephanie Moquin; Lynn Morris; Martha Nason; Yoshiaki Nishimura; Sijy O'Dell; Gilad Ofek; Marie Pancera; Stephen D Schmidt; Lawrence Shapiro; Sanjay Srivatsan; Ryan P Staupe; Tongqing Zhou; Peter D Kwong
Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.
Science (New York, N.Y.) 2013;340(6133):751-6.
2013: Jiang Zhu; S Munir Alam; Julie Blinn; Dennis R Burton; Joshua Eudailey; Barton F Haynes; Wayne C Koff; Krissey E Lloyd; Mark K Louder; Gabriel Lu; John R Mascola; Krisha McKee; James C Mullikin; Gilad Ofek; Marie Pancera; Robert Parks; Lawrence Shapiro; Melissa Simek; Jeff Skinner; Yongping Yang; Baoshan Zhang; Zhenhai Zhang; Peter D Kwong
Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(16):6470-5.
2013: Florian Klein; Peter D Kwong; Hugo Mouquet; Pamela J Bjorkman; Ron Diskin; Brooks Zhongzheng Fu; Christian Gaebler; Ivelin S Georgiev; Priyanthi N P Gnanapragasam; Reha-Baris Incesu; Thiago Y Oliveira; Marie Pancera; Johannes F Scheid; Michael S Seaman; Tongqing Zhou; Michel C Nussenzweig
Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization.
Cell 2013;153(1):126-38.
2013: Marie Pancera; Jonathan Stuckey; Yongping Yang; Jiang Zhu; Dennis R Burton; Jason Gorman; Wayne C Koff; Mark K Louder; Gabriel Lu; John R Mascola; Jason S McLellan; Peter D Kwong
N332-Directed broadly neutralizing antibodies use diverse modes of HIV-1 recognition: inferences from heavy-light chain complementation of function.
PloS one 2013;8(2):e55701.
2012: Andrés Finzi; Alon Herschhorn; Peter D Kwong; Beatriz Pacheco; Marie Pancera; Liping Wang; Shi-Hua Xiang; Xing Zeng; Anik Desormeaux; Joseph Sodroski
Lineage-specific differences between human and simian immunodeficiency virus regulation of gp120 trimer association and CD4 binding.
Journal of virology 2012;86(17):8974-86.
2012: Nicole A Doria-Rose; Ivelin Georgiev; Jason Gorman; Barton F Haynes; Wayne C Koff; Peter D Kwong; Jason S McLellan; Sijy O'Dell; Marie Pancera; Ryan P Staupe; Mattia Bonsignori; Dennis R Burton; Gwo-Yu Chuang; John R Mascola
A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodies.
Journal of virology 2012;86(15):8319-23.
2012: Jiang Zhu; Dennis R Burton; Wayne C Koff; John R Mascola; James C Mullikin; Sijy O'Dell; Gilad Ofek; Marie Pancera; Lawrence Shapiro; Melissa Simek; Xueling Wu; Baoshan Zhang; Zhenhai Zhang; Peter D Kwong
Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics.
Frontiers in microbiology 2012;3():315.
2011: Bimal K Chakrabarti; Javier Guenaga; John Mascola; Krisha McKee; Sijy O'Dell; Marie Pancera; Sanjay Phogat; James Robinson; Richard Wyatt
HIV type 1 Env precursor cleavage state affects recognition by both neutralizing and nonneutralizing gp41 antibodies.
AIDS research and human retroviruses 2011;27(8):877-87.
2011: Xueling Wu; Anita Changela; Sijy O'Dell; Stephen D Schmidt; Marie Pancera; Yongping Yang; Baoshan Zhang; Miroslaw K Gorny; Sanjay Phogat; James E Robinson; Leonidas Stamatatos; Susan Zolla-Pazner; Peter D Kwong; John R Mascola
Immunotypes of a quaternary site of HIV-1 vulnerability and their recognition by antibodies.
Journal of virology 2011;85(9):4578-85.
2011: Anita Changela; Xueling Wu; Yongping Yang; Baoshan Zhang; Jiang Zhu; Glenn A Nardone; Sijy O'Dell; Marie Pancera; Miroslaw K Gorny; Sanjay Phogat; James E Robinson; Leonidas Stamatatos; Susan Zolla-Pazner; John R Mascola; Peter D Kwong
Crystal structure of human antibody 2909 reveals conserved features of quaternary structure-specific antibodies that potently neutralize HIV-1.
Journal of virology 2011;85(6):2524-35.
2010: Marie Pancera; Jason S McLellan; Xueling Wu; Jiang Zhu; Anita Changela; Stephen D Schmidt; Yongping Yang; Tongqing Zhou; Sanjay Phogat; John R Mascola; Peter D Kwong
Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1.
Journal of virology 2010;84(16):8098-110.
2010: Andrés Finzi; Shi-Hua Xiang; Beatriz Pacheco; Liping Wang; Jessica Haight; Aemro Kassa; Brenda Danek; Marie Pancera; Peter D Kwong; Joseph Sodroski
Topological layers in the HIV-1 gp120 inner domain regulate gp41 interaction and CD4-triggered conformational transitions.
Molecular cell 2010;37(5):656-67.
2010: Marie Pancera; Shahzad Majeed; Yih-En Andrew Ban; Lei Chen; Chih-chin Huang; Leopold Kong; Young Do Kwon; Jonathan Stuckey; Tongqing Zhou; James E Robinson; William R Schief; Joseph Sodroski; Richard Wyatt; Peter D Kwong
Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(3):1166-71.
2009: Lei Chen; Young Do Kwon; Tongqing Zhou; Xueling Wu; Sijy O'Dell; Lisa Cavacini; Ann J Hessell; Marie Pancera; Min Tang; Ling Xu; Zhi-Yong Yang; Mei-Yun Zhang; James Arthos; Dennis R Burton; Dimiter S Dimitrov; Gary Nabel; Marshall R Posner; Joseph Sodroski; Richard Wyatt; John R Mascola; Peter D Kwong
Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science (New York, N.Y.) 2009;326(5956):1123-7.
2009: Aemro Kassa; Navid Madani; Arne Schön; Hillel Haim; Andrés Finzi; Shi-Hua Xiang; Liping Wang; Amy Princiotto; Marie Pancera; Joel Courter; Amos B Smith; Ernesto Freire; Peter D Kwong; Joseph Sodroski
Transitions to and from the CD4-bound conformation are modulated by a single-residue change in the human immunodeficiency virus type 1 gp120 inner domain.
Journal of virology 2009;83(17):8364-78.
2007: Barna Dey; Marie Pancera; Krisha Svehla; Yuuei Shu; Shi-Hua Xiang; Jeffrey Vainshtein; Yuxing Li; Joseph Sodroski; Peter D Kwong; John R Mascola; Richard Wyatt
Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity.
Journal of virology 2007;81(11):5579-93.
2005: Marie Pancera; Jacob Lebowitz; Arne Schön; Ping Zhu; Ernesto Freire; Peter D Kwong; Kenneth H Roux; Joseph Sodroski; Richard Wyatt
Soluble mimetics of human immunodeficiency virus type 1 viral spikes produced by replacement of the native trimerization domain with a heterologous trimerization motif: characterization and ligand binding analysis.
Journal of virology 2005;79(15):9954-69.
2005: Marie Pancera; Richard Wyatt
Selective recognition of oligomeric HIV-1 primary isolate envelope glycoproteins by potently neutralizing ligands requires efficient precursor cleavage.
Virology 2005;332(1):145-56.
2004: Christoph Grundner; Marie Pancera; Joung-Mo Kang; Markus Koch; Joseph Sodroski; Richard Wyatt
Factors limiting the immunogenicity of HIV-1 gp120 envelope glycoproteins.
Virology 2004;330(1):233-48.
2003: Markus Koch; Marie Pancera; Peter D Kwong; Peter Kolchinsky; Christoph Grundner; Liping Wang; Wayne A Hendrickson; Joseph Sodroski; Richard Wyatt
Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition.
Virology 2003;313(2):387-400.