Reynold Panettieri

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Damera G; Fogle H W; Lim P; Goncharova E A; Zhao H; Banerjee A; Tliba O; Krymskaya V P; Panettieri R A
Vitamin D inhibits growth of human airway smooth muscle cells through growth factor-induced phosphorylation of retinoblastoma protein and checkpoint kinase 1.
Goncharova Elena A; Goncharov Dmitry A; Damera Gautam; Tliba Omar; Amrani Yassine; Panettieri Reynold A; Krymskaya Vera P
Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis.
Damera Gautam; Tliba Omar; Panettieri Reynold A
Airway smooth muscle as an immunomodulatory cell.

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All Publications

2009: Damera G; Fogle H W; Lim P; Goncharova E A; Zhao H; Banerjee A; Tliba O; Krymskaya V P; Panettieri R A
Vitamin D inhibits growth of human airway smooth muscle cells through growth factor-induced phosphorylation of retinoblastoma protein and checkpoint kinase 1.
British journal of pharmacology 2009;158(6):1429-41.
2009: Goncharova Elena A; Goncharov Dmitry A; Damera Gautam; Tliba Omar; Amrani Yassine; Panettieri Reynold A; Krymskaya Vera P
Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis.
Molecular pharmacology 2009;76(4):766-77.
2009: Damera Gautam; Tliba Omar; Panettieri Reynold A
Airway smooth muscle as an immunomodulatory cell.
Pulmonary pharmacology & therapeutics 2009;22(5):353-9.
2009: Panettieri Reynold A; Spector Sheldon L; Tringale Michael; Mintz Matthew L
Patients' and primary care physicians' beliefs about asthma control and risk.
Allergy and asthma proceedings : the official journal of regional and state allergy societies 2009;30(5):519-28.
2009: Cohen Ethan David; Ihida-Stansbury Kaori; Lu Min Min; Panettieri Reynold A; Jones Peter Lloyd; Morrisey Edward E
Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway.
The Journal of clinical investigation 2009;119(9):2538-49.
2009: Cooper Philip R; Lamb Roberta; Day Nicole D; Branigan Patrick J; Kajekar Radhika; San Mateo Lani; Hornby Pamela J; Panettieri Reynold A
TLR3 activation stimulates cytokine secretion without altering agonist-induced human small airway contraction or relaxation.
American journal of physiology. Lung cellular and molecular physiology 2009;297(3):L530-7.
2009: Malavia Nikita K; Raub Christopher B; Mahon Sari B; Brenner Matthew; Panettieri Reynold A; George Steven C
Airway epithelium stimulates smooth muscle proliferation.
American journal of respiratory cell and molecular biology 2009;41(3):297-304.
2009: Panettieri Reynold A; MacIntyre Neil; Sims Michael; Kerwin Edward; Fogarty Charles; Noonan Michael; Claus Raymond; Andrews William T
Comparison of the efficacy and safety of arformoterol 15 microg twice daily and arformoterol 30 microg once daily in COPD: a single-dose, multicenter, randomized, modified-blind, two-way crossover study.
Clinical therapeutics 2009;31(8):1716-23.
2009: Sims Michael W; Margolis David J; Localio A Russell; Panettieri Reynold A; Kawut Steven M; Christie Jason D
Impact of pulmonary artery pressure on exercise function in severe COPD.
Chest 2009;136(2):412-9.
2009: Bailey Michael T; Kierstein Sonja; Sharma Satish; Spaits Matthew; Kinsey Steven G; Tliba Omar; Amrani Yassine; Sheridan John F; Panettieri Reynold A; Haczku Angela
Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(12):7888-96.
2009: Damera Gautam; Zhao Hengjiang; Wang Miao; Smith Michael; Kirby Christopher; Jester William F; Lawson John A; Panettieri Reynold A
Ozone modulates IL-6 secretion in human airway epithelial and smooth muscle cells.
American journal of physiology. Lung cellular and molecular physiology 2009;296(4):L674-83.
2009: Panettieri Reynold A
Asthma persistence versus progression: does airway smooth muscle function predict irreversible airflow obstruction?
Allergy and asthma proceedings : the official journal of regional and state allergy societies 2009;30(2):103-8.
2009: Tliba Omar; Panettieri Reynold A
Noncontractile functions of airway smooth muscle cells in asthma.
Annual review of physiology 2009;71():509-35.
2008: Cooper Philip R; Panettieri Reynold A
Steroids completely reverse albuterol-induced beta(2)-adrenergic receptor tolerance in human small airways.
The Journal of allergy and clinical immunology 2008;122(4):734-40.
2008: Kang Bit Na; Jude Joseph A; Panettieri Reynold A; Walseth Timothy F; Kannan Mathur S
Glucocorticoid regulation of CD38 expression in human airway smooth muscle cells: role of dual specificity phosphatase 1.
American journal of physiology. Lung cellular and molecular physiology 2008;295(1):L186-93.
2008: Mizuta Kentaro; Xu Dingbang; Pan Yaping; Comas George; Sonett Joshua R; Zhang Yi; Panettieri Reynold A; Yang Jay; Emala Charles W
GABAA receptors are expressed and facilitate relaxation in airway smooth muscle.
American journal of physiology. Lung cellular and molecular physiology 2008;294(6):L1206-16.
2008: Tliba Omar; Panettieri Reynold A
Regulation of inflammation by airway smooth muscle.
Current allergy and asthma reports 2008;8(3):262-8.
2008: Kierstein S; Krytska K; Sharma S; Amrani Y; Salmon M; Panettieri R A; Zangrilli J; Haczku A
Ozone inhalation induces exacerbation of eosinophilic airway inflammation and hyperresponsiveness in allergen-sensitized mice.
Allergy 2008;63(4):438-46.
2008: Panettieri Reynold A; Covar Ronina; Grant Evalyn; Hillyer Elizabeth V; Bacharier Leonard
Natural history of asthma: persistence versus progression-does the beginning predict the end?
The Journal of allergy and clinical immunology 2008;121(3):607-13.
2008: Mizuta Kentaro; Gallos George; Zhu Defen; Mizuta Fumiko; Goubaeva Farida; Xu Dingbang; Panettieri Reynold A; Yang Jay; Emala Charles W
Expression and coupling of neurokinin receptor subtypes to inositol phosphate and calcium signaling pathways in human airway smooth muscle cells.
American journal of physiology. Lung cellular and molecular physiology 2008;294(3):L523-34.
2008: Goncharova Elena A; Goncharov Dmitry A; Chisolm Amelia; Spaits Matthew S; Lim Poay N; Cesarone Gregory; Khavin Irene; Tliba Omar; Amrani Yassine; Panettieri Reynold A; Krymskaya Vera P
Interferon beta augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation.
Molecular pharmacology 2008;73(3):778-88.
2008: Panettieri Reynold A; Kotlikoff Michael I; Gerthoffer William T; Hershenson Marc B; Woodruff Prescott G; Hall Ian P; Banks-Schlegel Susan;
Airway smooth muscle in bronchial tone, inflammation, and remodeling: basic knowledge to clinical relevance.
American journal of respiratory and critical care medicine 2008;177(3):248-52.
2008: Misior Anna M; Yan Huandong; Pascual Rodolfo M; Deshpande Deepak A; Panettieri Reynold A; Penn Raymond B
Mitogenic effects of cytokines on smooth muscle are critically dependent on protein kinase A and are unmasked by steroids and cyclooxygenase inhibitors.
Molecular pharmacology 2008;73(2):566-74.
2008: Tliba Omar; Amrani Yassine; Panettieri Reynold A
Is airway smooth muscle the "missing link" modulating airway inflammation in asthma?
Chest 2008;133(1):236-42.
2008: Kassel Karen M; Wyatt Todd A; Panettieri Reynold A; Toews Myron L
Inhibition of human airway smooth muscle cell proliferation by beta 2-adrenergic receptors and cAMP is PKA independent: evidence for EPAC involvement.
American journal of physiology. Lung cellular and molecular physiology 2008;294(1):L131-8.
2008: Jain Deepika; Keslacy Stefan; Tliba Omar; Cao Yang; Kierstein Sonja; Amin Kunjlata; Panettieri Reynold A; Haczku Angela; Amrani Yassine
Essential role of IFNbeta and CD38 in TNFalpha-induced airway smooth muscle hyper-responsiveness.
Immunobiology 2008;213(6):499-509.
2008: Tirumurugaan Krishnaswamy G; Kang Bit Na; Panettieri Reynold A; Foster Douglas N; Walseth Timothy F; Kannan Mathur S
Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-alpha and dexamethasone.
Respiratory research 2008;9():26.
2008: Sims Michael W; Tal-Singer Ruth M; Kierstein Sonja; Musani Ali I; Beers Michael F; Panettieri Reynold A; Haczku Angela
Chronic obstructive pulmonary disease and inhaled steroids alter surfactant protein D (SP-D) levels: a cross-sectional study.
Respiratory research 2008;9():13.
2007: Hasaneen Nadia A; Zucker Stanley; Lin Richard Z; Vaday Gayle G; Panettieri Reynold A; Foda Hussein D
Angiogenesis is induced by airway smooth muscle strain.
American journal of physiology. Lung cellular and molecular physiology 2007;293(4):L1059-68.
2007: Panettieri Reynold A
In the clinic. Asthma.
Annals of internal medicine 2007;146(11):ITC6-1-ITC6-16.
2007: Kemeny Margaret E; Rosenwasser Lanny J; Panettieri Reynold A; Rose Robert M; Berg-Smith Steve M; Kline Joel N
Placebo response in asthma: a robust and objective phenomenon.
The Journal of allergy and clinical immunology 2007;119(6):1375-81.
2007: Tirumurugaan K G; Jude J A; Kang B N; Panettieri R A; Walseth T F; Kannan M S
TNF-alpha induced CD38 expression in human airway smooth muscle cells: role of MAP kinases and transcription factors NF-kappaB and AP-1.
American journal of physiology. Lung cellular and molecular physiology 2007;292(6):L1385-95.
2007: Osawa Yoko; Yim Peter D; Xu Dingbang; Panettieri Reynold A; Emala Charles W
Raf-1 kinase mediates adenylyl cyclase sensitization by TNF-alpha in human airway smooth muscle cells.
American journal of physiology. Lung cellular and molecular physiology 2007;292(6):L1414-21.
2007: Krymskaya Vera P; Panettieri Reynold A
Phosphodiesterases regulate airway smooth muscle function in health and disease.
Current topics in developmental biology 2007;79():61-74.
2006: Osawa Yoko; Xu Dingbang; Sternberg David; Sonett Joshua R; D'Armiento Jeanine; Panettieri Reynold A; Emala Charles W
Functional expression of the GABAB receptor in human airway smooth muscle.
American journal of physiology. Lung cellular and molecular physiology 2006;291(5):L923-31.
2006: Kong Kok Choi; Billington Charlotte K; Gandhi Uma; Panettieri Reynold A; Penn Raymond B
Cooperative mitogenic signaling by G protein-coupled receptors and growth factors is dependent on G(q/11).
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(9):1558-60.
2006: Kang Bit-Na; Tirumurugaan K G; Deshpande Deepak A; Amrani Yassine; Panettieri Reynold A; Walseth Timothy F; Kannan Mathur S
Transcriptional regulation of CD38 expression by tumor necrosis factor-alpha in human airway smooth muscle cells: role of NF-kappaB and sensitivity to glucocorticoids.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(7):1000-2.
2006: Lazaar Aili L; Panettieri Reynold A
Airway smooth muscle as a regulator of immune responses and bronchomotor tone.
Clinics in chest medicine 2006;27(1):53-69, vi.
2006: Pascual Rodolfo M; Carr Elizabeth M; Seeds Michael C; Guo Manhong; Panettieri Reynold A; Peters Stephen P; Penn Raymond B
Regulatory features of interleukin-1beta-mediated prostaglandin E2 synthesis in airway smooth muscle.
American journal of physiology. Lung cellular and molecular physiology 2006;290(3):L501-8.
2006: Pertel Thomas; Zhu Defen; Panettieri Reynold A; Yamaguchi Naoto; Emala Charles W; Hirshman Carol A
Expression and muscarinic receptor coupling of Lyn kinase in cultured human airway smooth muscle cells.
American journal of physiology. Lung cellular and molecular physiology 2006;290(3):L492-500.
2006: Zaidi Asifa K; Amrani Yassine; Panettieri Reynold A; Ali Hydar
Response to C3a, mast cells, and asthma.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(2):199.
2006: Faffe Débora S; Flynt Lesley; Bourgeois Kerri; Panettieri Reynold A; Shore Stephanie A
Interleukin-13 and interleukin-4 induce vascular endothelial growth factor release from airway smooth muscle cells: role of vascular endothelial growth factor genotype.
American journal of respiratory cell and molecular biology 2006;34(2):213-8.
2006: Goncharova Elena A; Lim Poay; Goncharov Dmitry A; Eszterhas Andrew; Panettieri Reynold A; Krymskaya Vera P
Assays for in vitro monitoring of proliferation of human airway smooth muscle (ASM) and human pulmonary arterial vascular smooth muscle (VSM) cells.
Nature protocols 2006;1(6):2905-8.
2006: Kierstein S; Poulain F R; Cao Y; Grous M; Mathias R; Kierstein G; Beers M F; Salmon M; Panettieri R A; Haczku A
Susceptibility to ozone-induced airway inflammation is associated with decreased levels of surfactant protein D.
Respiratory research 2006;7():85.
2005: Billington Charlotte K; Kong Kok C; Bhattacharyya Raja; Wedegaertner Philip B; Panettieri Reynold A; Chan Tung O; Penn Raymond B
Cooperative regulation of p70S6 kinase by receptor tyrosine kinases and G protein-coupled receptors augments airway smooth muscle growth.
Biochemistry 2005;44(44):14595-605.
2005: Haczku Angela; Emami Kiarash; Fischer Martin C; Kadlecek Stephen; Ishii Masaru; Panettieri Reynold A; Rizi Rahim R
Hyperpolarized 3He MRI in asthma measurements of regional ventilation following allergic sensitization and challenge in mice--preliminary results.
Academic radiology 2005;12(11):1362-70.
2005: Guo Manhong; Pascual Rodolfo M; Wang Siwei; Fontana Mary F; Valancius Cathryn A; Panettieri Reynold A; Tilley Stephen L; Penn Raymond B
Cytokines regulate beta-2-adrenergic receptor responsiveness in airway smooth muscle via multiple PKA- and EP2 receptor-dependent mechanisms.
Biochemistry 2005;44(42):13771-82.
2005: Huang Chien-Da; Ammit Alaina J; Tliba Omar; Kuo Han-Pin; Penn Raymond B; Panettieri Reynold A; Amrani Yassine
G-protein-coupled receptor agonists differentially regulate basal or tumor necrosis factor-alpha-stimulated activation of interleukin-6 and RANTES in human airway smooth muscle cells.
Journal of biomedical science 2005;12(5):763-76.
2005: Kim Jenny H; Jain Deepika; Tliba Omar; Yang Bei; Jester William F; Panettieri Reynold A; Amrani Yassine; Puré Ellen
TGF-beta potentiates airway smooth muscle responsiveness to bradykinin.
American journal of physiology. Lung cellular and molecular physiology 2005;289(4):L511-20.
2005: Lazaar Aili L; Panettieri Reynold A
Airway smooth muscle: a modulator of airway remodeling in asthma.
The Journal of allergy and clinical immunology 2005;116(3):488-95; quiz 496.
2005: Hasaneen Nadia A; Zucker Stanley; Cao Jian; Chiarelli Christian; Panettieri Reynold A; Foda Hussein D
Cyclic mechanical strain-induced proliferation and migration of human airway smooth muscle cells: role of EMMPRIN and MMPs.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(11):1507-9.
2005: Kang Bit Na; Deshpande Deepak A; Tirumurugaan K G; Panettieri Reynold A; Walseth Timothy F; Kannan Mathur S
Adenoviral mediated anti-sense CD38 attenuates TNF-alpha-induced changes in calcium homeostasis of human airway smooth muscle cells.
Canadian journal of physiology and pharmacology 2005;83(8-9):799-804.
2005: York Brian; Lou Dingyuan; Panettieri Reynold A; Krymskaya Vera P; Vanaman Thomas C; Noonan Daniel J
Cross-talk between tuberin, calmodulin, and estrogen signaling pathways.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(9):1202-4.
2005: Faffe Débora S; Flynt Lesley; Mellema Matthew; Whitehead Timothy R; Bourgeois Kerri; Panettieri Reynold A; Silverman Eric S; Shore Stephanie A
Oncostatin M causes VEGF release from human airway smooth muscle: synergy with IL-1beta.
American journal of physiology. Lung cellular and molecular physiology 2005;288(6):L1040-8.
2005: Hirshman Carol A; Zhu Defen; Pertel Thomas; Panettieri Reynold A; Emala Charles W
Isoproterenol induces actin depolymerization in human airway smooth muscle cells via activation of an Src kinase and GS.
American journal of physiology. Lung cellular and molecular physiology 2005;288(5):L924-31.
2005: Deshpande Deepak A; White Thomas A; Dogan Soner; Walseth Timothy F; Panettieri Reynold A; Kannan Mathur S
CD38/cyclic ADP-ribose signaling: role in the regulation of calcium homeostasis in airway smooth muscle.
American journal of physiology. Lung cellular and molecular physiology 2005;288(5):L773-88.
2005: Thangam E Berla; Venkatesha Rampura T; Zaidi Asifa K; Jordan-Sciutto Kelly L; Goncharov Dmitry A; Krymskaya Vera P; Amrani Yassine; Panettieri Reynold A; Ali Hydar
Airway smooth muscle cells enhance C3a-induced mast cell degranulation following cell-cell contact.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(7):798-800.
2005: Faffe Débora S; Flynt Lesley; Mellema Matthew; Moore Paul E; Silverman Eric S; Subramaniam Venkat; Jones Matthew R; Mizgerd Joseph P; Whitehead Timothy; Imrich Amy; Panettieri Reynold A; Shore Stephanie A
Oncostatin M causes eotaxin-1 release from airway smooth muscle: synergy with IL-4 and IL-13.
The Journal of allergy and clinical immunology 2005;115(3):514-20.
2005: Krymskaya Vera P; Goncharova Elena A; Ammit Alaina J; Lim Poay N; Goncharov Dmitry A; Eszterhas Andrew; Panettieri Reynold A
Src is necessary and sufficient for human airway smooth muscle cell proliferation and migration.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(3):428-30.
2005: Ali Hydar; Panettieri Reynold A
Anaphylatoxin C3a receptors in asthma.
Respiratory research 2005;6():19.
2005: Syed Farhat; Panettieri Reynold A; Tliba Omar; Huang Chris; Li Katherine; Bracht Michelle; Amegadzie Bernard; Griswold Don; Li Li; Amrani Yassine
The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells.
Respiratory research 2005;6():9.
2004: Panettieri Reynold A
Airway smooth muscle: immunomodulatory cells?
Allergy and asthma proceedings : the official journal of regional and state allergy societies 2004;25(6):381-6.
2004: Spector Z Z; Emami K; Fischer M C; Zhu J; Ishii M; Yu J; Kadlecek S; Driehuys B; Panettieri R A; Lipson D A; Gefter W; Shrager J; Rizi R R
A small animal model of regional alveolar ventilation using HP 3He MRI1.
Academic radiology 2004;11(10):1171-9.
2004: Howarth Peter H; Knox Alan J; Amrani Yassine; Tliba Omar; Panettieri Reynold A; Johnson Malcolm
Synthetic responses in airway smooth muscle.
The Journal of allergy and clinical immunology 2004;114(2 Suppl):S32-50.
2004: Tliba Omar; Panettieri Reynold A; Tliba Samira; Walseth Timothy F; Amrani Yassine
Tumor necrosis factor-alpha differentially regulates the expression of proinflammatory genes in human airway smooth muscle cells by activation of interferon-beta-dependent CD38 pathway.
Molecular pharmacology 2004;66(2):322-9.
2004: Deshpande Deepak A; Dogan Soner; Walseth Timothy F; Miller Steven M; Amrani Yassine; Panettieri Reynold A; Kannan Mathur S
Modulation of calcium signaling by interleukin-13 in human airway smooth muscle: role of CD38/cyclic adenosine diphosphate ribose pathway.
American journal of respiratory cell and molecular biology 2004;31(1):36-42.
2004: Amrani Yassine; Tliba Omar; Deshpande Deepak A; Walseth Timothy F; Kannan Mathur S; Panettieri Reynold A
Bronchial hyperresponsiveness: insights into new signaling molecules.
Current opinion in pharmacology 2004;4(3):230-4.
2004: Yang Guochang; Haczku Angela; Chen Hang; Martin Viviane; Galczenski Helen; Tomer Yaniv; Van Besien Christopher R; Evans Jilly F; Panettieri Reynold A; Funk Colin D;
Transgenic smooth muscle expression of the human CysLT1 receptor induces enhanced responsiveness of murine airways to leukotriene D4.
American journal of physiology. Lung cellular and molecular physiology 2004;286(5):L992-1001.
2004: Hardaker Elizabeth L; Bacon Alicia M; Carlson Karey; Roshak Amy K; Foley James J; Schmidt Dulcie B; Buckley Peter T; Comegys Meghan; Panettieri Reynold A; Sarau Henry M; Belmonte Kristen E
Regulation of TNF-alpha- and IFN-gamma-induced CXCL10 expression: participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(1):191-3.
2004: Panettieri Reynold A
Effects of corticosteroids on structural cells in asthma and chronic obstructive pulmonary disease.
Proceedings of the American Thoracic Society 2004;1(3):231-4.
2003: Lazaar Aili L; Panettieri Reynold A
Is airway remodeling clinically relevant in asthma?
The American journal of medicine 2003;115(8):652-9.
2003: Tliba Omar; Deshpande Deepak; Chen Hang; Van Besien Christopher; Kannan Mathur; Panettieri Reynold A; Amrani Yassine
IL-13 enhances agonist-evoked calcium signals and contractile responses in airway smooth muscle.
British journal of pharmacology 2003;140(7):1159-62.
2003: Tliba Omar; Tliba Samira; Da Huang Chien; Hoffman Rebecca K; DeLong Peter; Panettieri Reynold A; Amrani Yassine
Tumor necrosis factor alpha modulates airway smooth muscle function via the autocrine action of interferon beta.
The Journal of biological chemistry 2003;278(50):50615-23.
2003: Rosenfeldt Hans M; Amrani Yassine; Watterson Kenneth R; Murthy Karnam S; Panettieri Reynold A; Spiegel Sarah
Sphingosine-1-phosphate stimulates contraction of human airway smooth muscle cells.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(13):1789-99.
2003: Faffe Debora S; Whitehead Timothy; Moore Paul E; Baraldo Simonetta; Flynt Lesley; Bourgeois Kerri; Panettieri Reynold A; Shore Stephanie A
IL-13 and IL-4 promote TARC release in human airway smooth muscle cells: role of IL-4 receptor genotype.
American journal of physiology. Lung cellular and molecular physiology 2003;285(4):L907-14.
2003: Panettieri Reynold A
Airway smooth muscle: immunomodulatory cells that modulate airway remodeling?
Respiratory physiology & neurobiology 2003;137(2-3):277-93.
2003: Chen Hang; Tliba Omar; Van Besien Christopher R; Panettieri Reynold A; Amrani Yassine
TNF-[alpha] modulates murine tracheal rings responsiveness to G-protein-coupled receptor agonists and KCl.
Journal of applied physiology (Bethesda, Md. : 1985) 2003;95(2):864-72; discussion 863.
2003: Goncharova Elena A; Billington Charlotte K; Irani Carla; Vorotnikov Alexander V; Tkachuk Vsevolod A; Penn Raymond B; Krymskaya Vera P; Panettieri Reynold A
Cyclic AMP-mobilizing agents and glucocorticoids modulate human smooth muscle cell migration.
American journal of respiratory cell and molecular biology 2003;29(1):19-27.
2003: Amrani Yassine; Tliba Omar; Choubey Divaker; Huang Chien-Da; Krymskaya Vera P; Eszterhas Andrew; Lazaar Aili L; Panettieri Reynold A
IFN-gamma inhibits human airway smooth muscle cell proliferation by modulating the E2F-1/Rb pathway.
American journal of physiology. Lung cellular and molecular physiology 2003;284(6):L1063-71.
2003: Baraldo Simonetta; Faffe Deborah S; Moore Paul E; Whitehead Timothy; McKenna Matthew; Silverman Eric S; Panettieri Reynold A; Shore Stephanie A
Interleukin-9 influences chemokine release in airway smooth muscle: role of ERK.
American journal of physiology. Lung cellular and molecular physiology 2003;284(6):L1093-102.
2003: O'Dowd Liza C; Fife Daniel; Tenhave Thomas; Panettieri Reynold A
Attitudes of physicians toward objective measures of airway function in asthma.
The American journal of medicine 2003;114(5):391-6.
2003: Tilley Stephen L; Hartney John M; Erikson Christopher J; Jania Corey; Nguyen Mytrang; Stock Jeffrey; McNeisch John; Valancius Cathy; Panettieri Reynold A; Penn Raymond B; Koller Beverly H
Receptors and pathways mediating the effects of prostaglandin E2 on airway tone.
American journal of physiology. Lung cellular and molecular physiology 2003;284(4):L599-606.
2003: Pascual Rudolfo M; Awsare Bharat K; Farber Stephen A; Panettieri Reynold A; Peters Stephen P; Penn Raymond B
Regulation of phospholipase A2 by interleulin-1 in human airway smooth muscle.
Chest 2003;123(3 Suppl):433S-4S.
2003: Moore Paul E; Calder Mark M; Silverman Eric S; Panettieri Reynold A; Shore Stephanie A
Effect of dexamethasone on beta2-adrenergic desensitization in airway smooth muscle: role of the ARG19 polymorphism.
Chest 2003;123(3 Suppl):368S-9S.
2003: Huang Chien-Da; Tliba Omar; Panettieri Reynold A; Amrani Yassine
Bradykinin induces interleukin-6 production in human airway smooth muscle cells: modulation by Th2 cytokines and dexamethasone.
American journal of respiratory cell and molecular biology 2003;28(3):330-8.
2003: Amrani Yassine; Panettieri Reynold A
Airway smooth muscle: contraction and beyond.
The international journal of biochemistry & cell biology 2003;35(3):272-6.
2003: Deshpande Deepak A; Walseth Timothy F; Panettieri Reynold A; Kannan Mathur S
CD38/cyclic ADP-ribose-mediated Ca2+ signaling contributes to airway smooth muscle hyper-responsiveness.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(3):452-4.
2003: Holgate Stephen T; Peters-Golden Marc; Panettieri Reynold A; Henderson William R
Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodeling.
The Journal of allergy and clinical immunology 2003;111(1 Suppl):S18-34; discussion S34-6.
2003: Atochina Elena N; Beers Michael F; Tomer Yaniv; Scanlon Seth T; Russo Scott J; Panettieri Reynold A; Haczku Angela
Attenuated allergic airway hyperresponsiveness in C57BL/6 mice is associated with enhanced surfactant protein (SP)-D production following allergic sensitization.
Respiratory research 2003;4():15.
2003: Ammit Alaina J; Panettieri Reynold A
Airway smooth muscle cell hyperplasia: a therapeutic target in airway remodeling in asthma?
Progress in cell cycle research 2003;5():49-57.
2002: Panettieri Reynold A
Airway smooth muscle: an immunomodulatory cell.
The Journal of allergy and clinical immunology 2002;110(6 Suppl):S269-74.
2002: Lahiri Thomas; Moore Paul E; Baraldo Simonetta; Whitehead Timothy R; McKenna Matthew D; Panettieri Reynold A; Shore Stephanie A
Effect of IL-1beta on CRE-dependent gene expression in human airway smooth muscle cells.
American journal of physiology. Lung cellular and molecular physiology 2002;283(6):L1239-46.
2002: Goncharova Elena A; Ammit Alaina J; Irani Carla; Carroll Richard G; Eszterhas Andrew J; Panettieri Reynold A; Krymskaya Vera P
PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells.
American journal of physiology. Lung cellular and molecular physiology 2002;283(2):L354-63.
2002: Goncharova Elena A; Goncharov Dmitry A; Eszterhas Andrew; Hunter Deborah S; Glassberg Marilyn K; Yeung Raymond S; Walker Cheryl L; Noonan Daniel; Kwiatkowski David J; Chou Margaret M; Panettieri Reynold A; Krymskaya Vera P
Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM).
The Journal of biological chemistry 2002;277(34):30958-67.
2002: Lazaar Aili L; Plotnick Michael I; Kucich Umberto; Crichton Irene; Lotfi Shidan; Das Susan K P; Kane Sibyl; Rosenbloom Joel; Panettieri Reynold A; Schechter Norman M; Puré Ellen
Mast cell chymase modifies cell-matrix interactions and inhibits mitogen-induced proliferation of human airway smooth muscle cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(2):1014-20.
2002: Ammit Alaina J; Lazaar Aili L; Irani Carla; O'Neill Geraldine M; Gordon Nancy D; Amrani Yassine; Penn Raymond B; Panettieri Reynold A
Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells: modulation by glucocorticoids and beta-agonists.
American journal of respiratory cell and molecular biology 2002;26(4):465-74.
2002: Irani Carla; Goncharova Elena A; Hunter Deborah S; Walker Cheryl L; Panettieri Reynold A; Krymskaya Vera P
Phosphatidylinositol 3-kinase but not tuberin is required for PDGF-induced cell migration.
American journal of physiology. Lung cellular and molecular physiology 2002;282(4):L854-62.
2002: Moore Paul E; Church Trudi L; Chism David D; Panettieri Reynold A; Shore Stephanie A
IL-13 and IL-4 cause eotaxin release in human airway smooth muscle cells: a role for ERK.
American journal of physiology. Lung cellular and molecular physiology 2002;282(4):L847-53.
2002: Amrani Yassine; Panettieri Reynold A
Modulation of calcium homeostasis as a mechanism for altering smooth muscle responsiveness in asthma.
Current opinion in allergy and clinical immunology 2002;2(1):39-45.
2002: Goncharova Elena A; Vorotnikov Alexander V; Gracheva Elena O; Wang C L Albert; Panettieri Reynold A; Stepanova Victoria V; Tkachuk Vsevolod A
Activation of p38 MAP-kinase and caldesmon phosphorylation are essential for urokinase-induced human smooth muscle cell migration.
Biological chemistry 2002;383(1):115-26.
2001: Amrani Y; Moore P E; Hoffman R; Shore S A; Panettieri R A
Interferon-gamma modulates cysteinyl leukotriene receptor-1 expression and function in human airway myocytes.
American journal of respiratory and critical care medicine 2001;164(11):2098-101.
2001: Pascual R M; Billington C K; Hall I P; Panettieri R A; Fish J E; Peters S P; Penn R B
Mechanisms of cytokine effects on G protein-coupled receptor-mediated signaling in airway smooth muscle.
American journal of physiology. Lung cellular and molecular physiology 2001;281(6):L1425-35.
2001: Hirshman C A; Zhu D; Panettieri R A; Emala C W
Actin depolymerization via the beta-adrenoceptor in airway smooth muscle cells: a novel PKA-independent pathway.
American journal of physiology. Cell physiology 2001;281(5):C1468-76.
2001: Amrani Y; Ammit A J; Panettieri R A
Tumor necrosis factor receptor (TNFR) 1, but not TNFR2, mediates tumor necrosis factor-alpha-induced interleukin-6 and RANTES in human airway smooth muscle cells: role of p38 and p42/44 mitogen-activated protein kinases.
Molecular pharmacology 2001;60(4):646-55.
2001: Lesh R E; Emala C W; Lee H T; Zhu D; Panettieri R A; Hirshman C A
Inhibition of geranylgeranylation blocks agonist-induced actin reorganization in human airway smooth muscle cells.
American journal of physiology. Lung cellular and molecular physiology 2001;281(4):L824-31.
2001: Moore P E; Lahiri T; Laporte J D; Church T; Panettieri R A; Shore S A
Selected contribution: synergism between TNF-alpha and IL-1 beta in airway smooth muscle cells: implications for beta-adrenergic responsiveness.
Journal of applied physiology (Bethesda, Md. : 1985) 2001;91(3):1467-74.
2001: Ammit A J; Panettieri R A
Invited review: the circle of life: cell cycle regulation in airway smooth muscle.
Journal of applied physiology (Bethesda, Md. : 1985) 2001;91(3):1431-7.
2001: Fabry B; Maksym G N; Shore S A; Moore P E; Panettieri R A; Butler J P; Fredberg J J
Selected contribution: time course and heterogeneity of contractile responses in cultured human airway smooth muscle cells.
Journal of applied physiology (Bethesda, Md. : 1985) 2001;91(2):986-94.
2001: Penn R B; Pascual R M; Kim Y M; Mundell S J; Krymskaya V P; Panettieri R A; Benovic J L
Arrestin specificity for G protein-coupled receptors in human airway smooth muscle.
The Journal of biological chemistry 2001;276(35):32648-56.
2001: Haczku A; Atochina E N; Tomer Y; Chen H; Scanlon S T; Russo S; Xu J; Panettieri R A; Beers M F
Aspergillus fumigatus-induced allergic airway inflammation alters surfactant homeostasis and lung function in BALB/c mice.
American journal of respiratory cell and molecular biology 2001;25(1):45-50.
2001: Laporte J C; Moore P E; Baraldo S; Jouvin M H; Church T L; Schwartzman I N; Panettieri R A; Kinet J P; Shore S A
Direct effects of interleukin-13 on signaling pathways for physiological responses in cultured human airway smooth muscle cells.
American journal of respiratory and critical care medicine 2001;164(1):141-8.
2001: Lazaar A L; Panettieri R A
Airway smooth muscle as an immunomodulatory cell: a new target for pharmacotherapy?
Current opinion in pharmacology 2001;1(3):259-64.
2001: Lahiri T; Laporte J D; Moore P E; Panettieri R A; Shore S A
Interleukin-6 family cytokines: signaling and effects in human airway smooth muscle cells.
American journal of physiology. Lung cellular and molecular physiology 2001;280(6):L1225-32.
2001: Ammit A J; Hastie A T; Edsall L C; Hoffman R K; Amrani Y; Krymskaya V P; Kane S A; Peters S P; Penn R B; Spiegel S; Panettieri R A
Sphingosine 1-phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(7):1212-4.
2001: Krymskaya V P; Ammit A J; Hoffman R K; Eszterhas A J; Panettieri R A
Activation of class IA PI3K stimulates DNA synthesis in human airway smooth muscle cells.
American journal of physiology. Lung cellular and molecular physiology 2001;280(5):L1009-18.
2001: Mundell S J; Olah M E; Panettieri R A; Benovic J L; Penn R B
Regulation of G protein-coupled receptor-adenylyl cyclase responsiveness in human airway smooth muscle by exogenous and autocrine adenosine.
American journal of respiratory cell and molecular biology 2001;24(2):155-63.
2000: Moore P E; Laporte J D; Abraham J H; Schwartzman I N; Yandava C N; Silverman E S; Drazen J M; Wand M P; Panettieri R A; Shore S A
Polymorphism of the beta(2)-adrenergic receptor gene and desensitization in human airway smooth muscle.
American journal of respiratory and critical care medicine 2000;162(6):2117-24.
2000: Ammit A J; Hoffman R K; Amrani Y; Lazaar A L; Hay D W; Torphy T J; Penn R B; Panettieri R A
Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth-muscle cells. Modulation by cyclic adenosine monophosphate.
American journal of respiratory cell and molecular biology 2000;23(6):794-802.
2000: Laporte J D; Moore P E; Lahiri T; Schwartzman I N; Panettieri R A; Shore S A
p38 MAP kinase regulates IL-1 beta responses in cultured airway smooth muscle cells.
American journal of physiology. Lung cellular and molecular physiology 2000;279(5):L932-41.
2000: Krymskaya V P; Orsini M J; Eszterhas A J; Brodbeck K C; Benovic J L; Panettieri R A; Penn R B
Mechanisms of proliferation synergy by receptor tyrosine kinase and G protein-coupled receptor activation in human airway smooth muscle.
American journal of respiratory cell and molecular biology 2000;23(4):546-54.
2000: Amrani Y; Lazaar A L; Hoffman R; Amin K; Ousmer S; Panettieri R A
Activation of p55 tumor necrosis factor-alpha receptor-1 coupled to tumor necrosis factor receptor-associated factor 2 stimulates intercellular adhesion molecule-1 expression by modulating a thapsigargin-sensitive pathway in human tracheal smooth muscle cells.
Molecular pharmacology 2000;58(1):237-45.
2000: Amrani Y; Chen H; Panettieri R A
Activation of tumor necrosis factor receptor 1 in airway smooth muscle: a potential pathway that modulates bronchial hyper-responsiveness in asthma?
Respiratory research 2000;1(1):49-53.
1999: Ammit A J; Kane S A; Panettieri R A
Activation of K-p21ras and N-p21ras, but not H-p21ras, is necessary for mitogen-induced human airway smooth-muscle proliferation.
American journal of respiratory cell and molecular biology 1999;21(6):719-27.
1999: Laporte J D; Moore P E; Abraham J H; Maksym G N; Fabry B; Panettieri R A; Shore S A
Role of ERK MAP kinases in responses of cultured human airway smooth muscle cells to IL-1beta.
The American journal of physiology 1999;277(5 Pt 1):L943-51.
1999: Moore P E; Laporte J D; Gonzalez S; Moller W; Heyder J; Panettieri R A; Shore S A
Glucocorticoids ablate IL-1beta-induced beta-adrenergic hyporesponsiveness in human airway smooth muscle cells.
The American journal of physiology 1999;277(5 Pt 1):L932-42.
1999: Billington C K; Hall I P; Mundell S J; Parent J L; Panettieri R A; Benovic J L; Penn R B
Inflammatory and contractile agents sensitize specific adenylyl cyclase isoforms in human airway smooth muscle.
American journal of respiratory cell and molecular biology 1999;21(5):597-606.
1999: Orsini M J; Krymskaya V P; Eszterhas A J; Benovic J L; Panettieri R A; Penn R B
MAPK superfamily activation in human airway smooth muscle: mitogenesis requires prolonged p42/p44 activation.
The American journal of physiology 1999;277(3 Pt 1):L479-88.
1999: Amrani Y; Lazaar A L; Panettieri R A
Up-regulation of ICAM-1 by cytokines in human tracheal smooth muscle cells involves an NF-kappa B-dependent signaling pathway that is only partially sensitive to dexamethasone.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(4):2128-34.
1999: Foda H D; George S; Rollo E; Drews M; Conner C; Cao J; Panettieri R A; Zucker S
Regulation of gelatinases in human airway smooth muscle cells: mechanism of progelatinase A activation.
The American journal of physiology 1999;277(1 Pt 1):L174-82.
1999: Krymskaya V P; Penn R B; Orsini M J; Scott P H; Plevin R J; Walker T R; Eszterhas A J; Amrani Y; Chilvers E R; Panettieri R A
Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation.
The American journal of physiology 1999;277(1 Pt 1):L65-78.
1999: Krymskaya V P; Hoffman R; Eszterhas A; Kane S; Ciocca V; Panettieri R A
EGF activates ErbB-2 and stimulates phosphatidylinositol 3-kinase in human airway smooth muscle cells.
The American journal of physiology 1999;276(2 Pt 1):L246-55.
1999: Penn R B; Parent J L; Pronin A N; Panettieri R A; Benovic J L
Pharmacological inhibition of protein kinases in intact cells: antagonism of beta adrenergic receptor ligand binding by H-89 reveals limitations of usefulness.
The Journal of pharmacology and experimental therapeutics 1999;288(2):428-37.
1998: Walker T R; Moore S M; Lawson M F; Panettieri R A; Chilvers E R
Platelet-derived growth factor-BB and thrombin activate phosphoinositide 3-kinase and protein kinase B: role in mediating airway smooth muscle proliferation.
Molecular pharmacology 1998;54(6):1007-15.
1998: Panettieri R A
Cellular and molecular mechanisms regulating airway smooth muscle proliferation and cell adhesion molecule expression.
American journal of respiratory and critical care medicine 1998;158(5 Pt 3):S133-40.
1998: Lazaar A L; Amrani Y; Hsu J; Panettieri R A; Fanslow W C; Albelda S M; Puré E
CD40-mediated signal transduction in human airway smooth muscle.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(6):3120-7.
1998: Panettieri R A; Tan E M; Ciocca V; Luttmann M A; Leonard T B; Hay D W
Effects of LTD4 on human airway smooth muscle cell proliferation, matrix expression, and contraction In vitro: differential sensitivity to cysteinyl leukotriene receptor antagonists.
American journal of respiratory cell and molecular biology 1998;19(3):453-61.
1998: Laporte J D; Moore P E; Panettieri R A; Moeller W; Heyder J; Shore S A
Prostanoids mediate IL-1beta-induced beta-adrenergic hyporesponsiveness in human airway smooth muscle cells.
The American journal of physiology 1998;275(3 Pt 1):L491-501.
1998: Amrani Y; Panettieri R A
Cytokines induce airway smooth muscle cell hyperresponsiveness to contractile agonists.
Thorax 1998;53(8):713-6.
1998: Penn R B; Panettieri R A; Benovic J L
Mechanisms of acute desensitization of the beta2AR-adenylyl cyclase pathway in human airway smooth muscle.
American journal of respiratory cell and molecular biology 1998;19(2):338-48.
1998: Panettieri R A; Murray R K; Eszterhas A J; Bilgen G; Martin J G
Repeated allergen inhalations induce DNA synthesis in airway smooth muscle and epithelial cells in vivo.
The American journal of physiology 1998;274(3 Pt 1):L417-24.
1997: Krymskaya V P; Hoffman R; Eszterhas A; Ciocca V; Panettieri R A
TGF-beta 1 modulates EGF-stimulated phosphatidylinositol 3-kinase activity in human airway smooth muscle cells.
The American journal of physiology 1997;273(6 Pt 1):L1220-7.
1997: Amrani Y; Krymskaya V; Maki C; Panettieri R A
Mechanisms underlying TNF-alpha effects on agonist-mediated calcium homeostasis in human airway smooth muscle cells.
The American journal of physiology 1997;273(5 Pt 1):L1020-8.
1997: Shore S A; Laporte J; Hall I P; Hardy E; Panettieri R A
Effect of IL-1 beta on responses of cultured human airway smooth muscle cells to bronchodilator agonists.
American journal of respiratory cell and molecular biology 1997;16(6):702-12.
1997: Cohen M D; Ciocca V; Panettieri R A
TGF-beta 1 modulates human airway smooth-muscle cell proliferation induced by mitogens.
American journal of respiratory cell and molecular biology 1997;16(1):85-90.
1997: Lazaar A L; Reitz H E; Panettieri R A; Peters S P; Puré E
Antigen receptor-stimulated peripheral blood and bronchoalveolar lavage-derived T cells induce MHC class II and ICAM-1 expression on human airway smooth muscle.
American journal of respiratory cell and molecular biology 1997;16(1):38-45.
1996: Hubmayr R D; Shore S A; Fredberg J J; Planus E; Panettieri R A; Moller W; Heyder J; Wang N
Pharmacological activation changes stiffness of cultured human airway smooth muscle cells.
The American journal of physiology 1996;271(5 Pt 1):C1660-8.
1996: Amrani Y; Panettieri R A; Frossard N; Bronner C
Activation of the TNF alpha-p55 receptor induces myocyte proliferation and modulates agonist-evoked calcium transients in cultured human tracheal smooth muscle cells.
American journal of respiratory cell and molecular biology 1996;15(1):55-63.
1996: Panettieri R A; Goldie R G; Rigby P J; Eszterhas A J; Hay D W
Endothelin-1-induced potentiation of human airway smooth muscle proliferation: an ETA receptor-mediated phenomenon.
British journal of pharmacology 1996;118(1):191-7.
1995: Panettieri R A; Hall I P; Maki C S; Murray R K
alpha-Thrombin increases cytosolic calcium and induces human airway smooth muscle cell proliferation.
American journal of respiratory cell and molecular biology 1995;13(2):205-16.
1995: Panettieri R A; Murray R K; Bilgen G; Eszterhas A J; Martin J G
Repeated allergen inhalations induce DNA synthesis in airway smooth muscle and epithelial cells in vivo.
Chest 1995;107(3 Suppl):94S-95S.
1995: Panettieri R A; Lazaar A L; Puré E; Albelda S M
Activation of cAMP-dependent pathways in human airway smooth muscle cells inhibits TNF-alpha-induced ICAM-1 and VCAM-1 expression and T lymphocyte adhesion.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(5):2358-65.
1995: Puré E; Camp R L; Peritt D; Panettieri R A; Lazaar A L; Nayak S
Defective phosphorylation and hyaluronate binding of CD44 with point mutations in the cytoplasmic domain.
The Journal of experimental medicine 1995;181(1):55-62.
1994: Pilewski J M; Panettieri R A; Kaiser L R; Albelda S M
Expression of endothelial cell adhesion molecules in human bronchial xenografts.
American journal of respiratory and critical care medicine 1994;150(3):795-801.
1994: Lazaar A L; Albelda S M; Pilewski J M; Brennan B; Puré E; Panettieri R A
T lymphocytes adhere to airway smooth muscle cells via integrins and CD44 and induce smooth muscle cell DNA synthesis.
The Journal of experimental medicine 1994;180(3):807-16.
1991: Stedman H H; Sweeney H L; Shrager J B; Maguire H C; Panettieri R A; Petrof B; Narusawa M; Leferovich J M; Sladky J T; Kelly A M
The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy.
Nature 1991;352(6335):536-9.
1991: Kelly A M; Rosser B W; Hoffman R; Panettieri R A; Schiaffino S; Rubinstein N A; Nemeth P M
Metabolic and contractile protein expression in developing rat diaphragm muscle.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1991;11(5):1231-42.
1990: Panettieri R A; Yadvish P A; Kelly A M; Rubinstein N A; Kotlikoff M I
Histamine stimulates proliferation of airway smooth muscle and induces c-fos expression.
The American journal of physiology 1990;259(6 Pt 1):L365-71.
1989: Panettieri R A; Murray R K; DePalo L R; Yadvish P A; Kotlikoff M I
A human airway smooth muscle cell line that retains physiological responsiveness.
The American journal of physiology 1989;256(2 Pt 1):C329-35.

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