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Klaus Pantel

Research Profile

Disorders

Anatomy

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Immunohistochemistry

Chemicals & Drugs

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Physiology

Gene Expression Regulation, Neoplastic

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Ellen Heitzer; Eva Maria Hoffmann; Gerald Hoefler; Carolin Lackner; Sigurd Lax; Oliver Mauermann; Klaus Pantel; Martin Pichler; Sabine Riethdorf; Hellmut Samonigg; Heinz Sill; Martina Auer; Thomas Bauernhofer; Florian Eisner; Christin Gasch; Jochen B Geigl; Peter Ulz; Julie Waldispuehl-Geigl; Michael R Speicher
Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing.
Tobias M Gorges; Klaus Pantel
Circulating tumor cells as therapy-related biomarkers in cancer patients.
Benjamin Otto; Klaus Pantel; Udo Schumacher; Reiner Siebert; Thomas Streichert; Lars O Baumbusch; Wolfgang Deppert; Katharina Gruner; Christina Heinlein; José Ignacio Martin-Subero; Peter Nollau; Christoph Wagener; Florian Wegwitz; Bauke Ylstra; Genrich V Tolstonog
Low-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression.

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All Publications

2013: Ellen Heitzer; Eva Maria Hoffmann; Gerald Hoefler; Carolin Lackner; Sigurd Lax; Oliver Mauermann; Klaus Pantel; Martin Pichler; Sabine Riethdorf; Hellmut Samonigg; Heinz Sill; Martina Auer; Thomas Bauernhofer; Florian Eisner; Christin Gasch; Jochen B Geigl; Peter Ulz; Julie Waldispuehl-Geigl; Michael R Speicher
Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing.
Cancer research 2013;73(10):2965-75.
2013: Tobias M Gorges; Klaus Pantel
Circulating tumor cells as therapy-related biomarkers in cancer patients.
Cancer immunology, immunotherapy : CII 2013;62(5):931-9.
2013: Benjamin Otto; Klaus Pantel; Udo Schumacher; Reiner Siebert; Thomas Streichert; Lars O Baumbusch; Wolfgang Deppert; Katharina Gruner; Christina Heinlein; José Ignacio Martin-Subero; Peter Nollau; Christoph Wagener; Florian Wegwitz; Bauke Ylstra; Genrich V Tolstonog
Low-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression.
International journal of cancer. Journal international du cancer 2013;132(6):1300-10.
2013: Tobias J Grob; Tobias Hoenig; Jakob R Izbicki; Hans Klose; Alexandra M Koenig; Klaus Pantel; Guido Sauter; Ronald Simon; Yogesh Vashist; Djordje Atanackovic; Carsten Bokemeyer; Till S Clauditz; Waldemar Wilczak
Frequent intratumoral heterogeneity of EGFR gene copy gain in non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2013;79(3):221-7.
2013: Simon A Joosse; Klaus Pantel
Biologic challenges in the detection of circulating tumor cells.
Cancer research 2013;73(1):8-11.
2013: Markus Wallwiener; Bahriye Aktas; Irène Baccelli; Andreas Daniel Hartkopf; Wolfgang Janni; Frederik Marmé; Volkmar Müller; Klaus Pantel; Brigitte Rack; Sabine Riethdorf; Andreas Schneeweiss; Sarah Schott; Christof Sohn; Erich-Franz Solomayer; Andreas Trumpp; Tanja Natascha Fehm
The prognostic impact of circulating tumor cells in subtypes of metastatic breast cancer.
Breast cancer research and treatment 2013;137(2):503-10.
2013: Christin Gasch; Jakob R Izbicki; Sabine Langer-Freitag; Oliver Mauermann; Klaus Pantel; Martin Pichler; Matthias Reeh; Thomas Bauernhofer; Adrian M Seifert; Sabine Riethdorf
Heterogeneity of epidermal growth factor receptor status and mutations of KRAS/PIK3CA in circulating tumor cells of patients with colorectal cancer.
Clinical chemistry 2013;59(1):252-60.
2012: Natalia Bednarz-Knoll; Catherine Alix-Panabières; Klaus Pantel
Plasticity of disseminating cancer cells in patients with epithelial malignancies.
Cancer metastasis reviews 2012;31(3-4):673-87.
2012: Alexander Schultze; Emre Yekebas; Klaus Pantel; Uta Reichelt; Sabine Riethdorf; Thomas Schmidt; Isabel Ben Batalla; Carsten Bokemeyer; Michael Bubenheim; Katharina E Effenberger; Andreas Erbersdobler; Walter Fiedler; Jakob R Izbicki; Sonja Loges
VEGFR-1 expression levels predict occurrence of disseminated tumor cells in the bone marrow of patients with esophageal carcinoma.
Clinical & experimental metastasis 2012;29(8):879-87.
2012: Klaus Pantel; Catherine Alix-Panabières
The potential of circulating tumor cells as a liquid biopsy to guide therapy in prostate cancer.
Cancer discovery 2012;2(11):974-5.
2012: Dharanija Madhavan; Caroline Modugno; Klaus Pantel; Sabine Riethdorf; Martina Scharpff; Andreas Schneeweiss; Sarah Schott; Christof Sohn; Andreas Trumpp; Andrey Turchinovich; Markus Wallwiener; Rongxi Yang; Manuela Zucknick; Axel Benner; Katarina Cuk; Jörg Heil; Barbara Burwinkel
Circulating miRNAs as surrogate markers for circulating tumor cells and prognostic markers in metastatic breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(21):5972-82.
2012: Heidi Schwarzenbach; Brigitte Rack; Corinna Eichelser; Wolfgang Janni; Jolanthe Kropidlowski; Klaus Pantel
Loss of heterozygosity at tumor suppressor genes detectable on fractionated circulating cell-free tumor DNA as indicator of breast cancer progression.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(20):5719-30.
2012: Liling Zhang; Junli Liu; Gang Peng; Sabine Riethdorf; Tao Wang; Gang Wu; Kunyu Yang; Klaus Pantel
Meta-analysis of the prognostic value of circulating tumor cells in breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(20):5701-10.
2012: Aline Taenzer; Harriet Wikman; Catherine Alix-Panabières; Klaus Pantel
Circulating tumor-derived biomarkers in lung cancer.
Journal of thoracic disease 2012;4(5):448-9.
2012: Klaus Pantel; Catherine Alix-Panabières
Detection methods of circulating tumor cells.
Journal of thoracic disease 2012;4(5):446-7.
2012: Randi R Mathiesen; Oliver Mauermann; Bjørn Naume; Gro Nilsen; Anna C Obenauf; Klaus Pantel; Sabine Riethdorf; Inga H Rye; Ida J Schneider; Michael R Speicher; Elin Borgen; Anne-Lise Børresen-Dale; Ole Christian Lingjaerde; Eldri U Due; Renathe Fjelldal; Jochen B Geigl; Knut Liestøl; Lars O Baumbusch
High-resolution analyses of copy number changes in disseminated tumor cells of patients with breast cancer.
International journal of cancer. Journal international du cancer 2012;131(4):E405-15.
2012: Katharina E Effenberger; Christine Eulenburg; Jakob R Izbicki; Klaus Pantel; Matthias Reeh; Sabine Riethdorf; Cornelia Schroeder; Michael Tachezy; Yogesh Vashist; Maximilian Bockhorn
Disseminated tumor cells in pancreatic cancer-an independent prognosticator of disease progression and survival.
International journal of cancer. Journal international du cancer 2012;131(4):E475-83.
2012: Heidi Schwarzenbach; Bettina Steinbach; Karin Milde-Langosch; Volkmar Müller; Klaus Pantel
Diagnostic potential of PTEN-targeting miR-214 in the blood of breast cancer patients.
Breast cancer research and treatment 2012;134(3):933-41.
2012: Michael Tachezy; Yogesh Vashist; Hilke Zander; Katharina Effenberger; Florian Gebauer; Jakob R Izbicki; Sarah Minner; Klaus Pantel; Guido Sauter; Maximilian Bockhorn
ALCAM (CD166) expression and serum levels are markers for poor survival of esophageal cancer patients.
International journal of cancer. Journal international du cancer 2012;131(2):396-405.
2012: Faik G Uzunoglu; Harriet Wikman; Maximilian Bockhorn; Benjamin A Bohn; Cenap Güngör; Jakob R Izbicki; Caroline Kaufmann; Asad Kutup; Oliver Mann; Michael F Nentwich; Klaus Pantel; Matthias Reeh; Yogesh Vashist
Vascular endothelial growth factor receptor 2 gene polymorphisms as predictors for tumor recurrence and overall survival in non-small-cell lung cancer.
Annals of surgical oncology 2012;19(7):2159-68.
2012: Yogesh Vashist; Eik Vettorazzi; Emre F Yekebas; Katharina E Effenberger; Jakob R Izbicki; Sabine Riethdorf; Klaus Pantel
Disseminated tumor cells in bone marrow and the natural course of resected esophageal cancer.
Annals of surgery 2012;255(6):1105-12.
2012: Lena Deutsch; Markus Glatzel; Andrea Hinsch; Jakob R Izbicki; Susann Koops; Asad Kutup; Klaus Pantel; Guido Sauter; Faik G Uzunoglu; Michaela Wrage; Harriet Wikman
Opposite roles of FOXA1 and NKX2-1 in lung cancer progression.
Genes, chromosomes & cancer 2012;51(6):618-29.
2012: Klaus Pantel; Sabine Riethdorf; Jean-Pierre Vendrell; Amandine Coffy; Eric Denève; Thierry Maudelonde; David Nocca; Catherine Alix-Panabières
Circulating epithelial cells in patients with benign colon diseases.
Clinical chemistry 2012;58(5):936-40.
2012: Michael Rink; Shahrokh F Shariat; Armin Soave; Malgorzata Stoupiec; Sascha A Ahyai; fianceeyi chun; Cornelia Coith; Roland Dahlem; Margit Fisch; Martin G Friedrich; Jens Hansen; Luis A Kluth; Sarah Minner; Klaus Pantel; Sabine Riethdorf
Prognostic role and HER2 expression of circulating tumor cells in peripheral blood of patients prior to radical cystectomy: a prospective study.
European urology 2012;61(4):810-7.
2012: Kai Bartkowiak; Sabine Riethdorf; Klaus Pantel
The interrelating dynamics of hypoxic tumor microenvironments and cancer cell phenotypes in cancer metastasis.
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2012;5(1):59-72.
2012: Fred Saad; Klaus Pantel
The current role of circulating tumor cells in the diagnosis and management of bone metastases in advanced prostate cancer.
Future oncology (London, England) 2012;8(3):321-31.
2012: Simon A Joosse; Volkmar Müller; Antje Andreas; Andreas Bauche; Juliane Hannemann; Julia Spötter; Klaus Pantel
Changes in keratin expression during metastatic progression of breast cancer: impact on the detection of circulating tumor cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(4):993-1003.
2012: Harriet Wikman; Isabell Witzel; Guido Sauter; Bettina Sielaff-Frimpong; Manfred Westphal; Jolanthe Kropidlowski; Katrin Lamszus; Karin Milde-Langosch; Klaus Pantel
Clinical relevance of loss of 11p15 in primary and metastatic breast cancer: association with loss of PRKCDBP expression in brain metastases.
PloS one 2012;7(10):e47537.
2012: Carina Roth; Jakob R Izbicki; Klaus Pantel; Isabel Stückrath; Michael Tachezy; Heidi Schwarzenbach
Low levels of cell-free circulating miR-361-3p and miR-625* as blood-based markers for discriminating malignant from benign lung tumors.
PloS one 2012;7(6):e38248.
2012: Stephan Braun; Klaus Pantel
Immunocytochemical detection and characterisation of individual micrometastatic tumour cells.
Methods in molecular biology (Clifton, N.J.) 2012;878():63-70.
2012: Harriet Wikman; Michaela Wrage; Bauke Ylstra; Marc Zapatka; Guido Sauter; Liubov Uslar; Manfred Westphal; Christian Benner; Niclas Detels; Kathrin Eylmann; Markus Glatzel; Ina Hohensee; Dirk Kemming; Katrin Lamszus; Volkmar Müller; Klaus Pantel
Relevance of PTEN loss in brain metastasis formation in breast cancer patients.
Breast cancer research : BCR 2012;14(2):R49.
2012: Catherine Alix-Panabières; Heidi Schwarzenbach; Klaus Pantel
Circulating tumor cells and circulating tumor DNA.
Annual review of medicine 2012;63():199-215.
2011: Nicole Grabinski; Katharina Grupp; Kai Bartkowiak; Burkhard Brandt; Klaus Pantel; Manfred Jücker
Distinct functional roles of Akt isoforms for proliferation, survival, migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells.
Cellular signalling 2011;23(12):1952-60.
2011: Heidi Schwarzenbach; Bettina Steinbach; Karin Milde-Langosch; Volkmar Müller; Klaus Pantel
Evaluation of cell-free tumour DNA and RNA in patients with breast cancer and benign breast disease.
Molecular bioSystems 2011;7(10):2848-54.
2011: Sibyll Hein; Maike Ihnen; Rana Issa; Fritz Jänicke; Nadine Köhler; Sylke Krenkel; Volkmar Müller; Klaus Pantel; Sabine Riethdorf; Michaela Schweizer; Thomas Streichert; Harriet Wikman; Volker Assmann; Katrin Beck; Karin Milde-Langosch
Biologic role of activated leukocyte cell adhesion molecule overexpression in breast cancer cell lines and clinical tumor tissue.
Breast cancer research and treatment 2011;129(2):347-60.
2011: Yogesh Vashist; Emre F Yekebas; Oliver Zehler; Maximillian Bockhorn; Guellue Cataldegirmen; Katharina Effenberger; Viacheslav Kalinin; Alexandra Koenig; Asad Kutup; Sormeh Mina; Safije Musici; Klaus Pantel; Guentac Uzunoglu; Jakob R Izbicki
The GNAS1 T393C single nucleotide polymorphism predicts the natural postoperative course of complete resected esophageal cancer.
Cellular oncology (Dordrecht) 2011;34(4):281-8.
2011: Heidi Schwarzenbach; Dave S B Hoon; Klaus Pantel
Cell-free nucleic acids as biomarkers in cancer patients.
Nature reviews. Cancer 2011;11(6):426-37.
2011: Carina Roth; Sabine Kasimir-Bauer; Klaus Pantel; Heidi Schwarzenbach
Screening for circulating nucleic acids and caspase activity in the peripheral blood as potential diagnostic tools in lung cancer.
Molecular oncology 2011;5(3):281-91.
2011: Pauline Wimberger; Carina Roth; Klaus Pantel; Sabine Kasimir-Bauer; Rainer Kimmig; Heidi Schwarzenbach
Impact of platinum-based chemotherapy on circulating nucleic acid levels, protease activities in blood and disseminated tumor cells in bone marrow of ovarian cancer patients.
International journal of cancer. Journal international du cancer 2011;128(11):2572-80.
2011: Dave S B Hoon; Robert Ferris; Ryo Tanaka; Kelly K Chong; Catherine Alix-Panabières; Klaus Pantel
Molecular mechanisms of metastasis.
Journal of surgical oncology 2011;103(6):508-17.
2011: Wolfgang Janni; Julia Jückstock; Elin Borgen; Stephan Braun; Tanja Fehm; Klaus Friese; Jahn Nesland; Klaus Pantel; Brigitte Rack; Erich Solomayer; Harald Sommer; Marit Synnestvedt; Florian D Vogl; Gro Wiedswang; Bjørn Naume
Persistence of disseminated tumor cells in the bone marrow of breast cancer patients predicts increased risk for relapse--a European pooled analysis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(9):2967-76.
2011: Heidi Schwarzenbach; Felix K-H Chun; Hendrik Isbarn; Hartwig Huland; Klaus Pantel
Genomic profiling of cell-free DNA in blood and bone marrow of prostate cancer patients.
Journal of cancer research and clinical oncology 2011;137(5):811-9.
2011: Katharina E Effenberger; Elin Borgen; Christine Zu Eulenburg; Kai Bartkowiak; Andrea Grosser; Marit Synnestvedt; Rolf Kaaresen; Burkhard Brandt; Jahn M Nesland; Klaus Pantel; Bjorn Naume
Detection and clinical relevance of early disseminated breast cancer cells depend on their cytokeratin expression pattern.
Breast cancer research and treatment 2011;125(3):729-38.
2011: Sabine Riethdorf; Bernhard Hoegel; Birgit John; German Ott; Peter Fritz; Susanne Thon; Thomas Loening; Klaus Pantel
Prospective multi-centre study to validate chromogenic in situ hybridisation for the assessment of HER2 gene amplification in specimens from adjuvant and metastatic breast cancer patients.
Journal of cancer research and clinical oncology 2011;137(2):261-9.
2011: J-W Kornfeld; S Meder; M Wohlberg; Reinhard E Friedrich; Thomas Rau; Lutz Riethdorf; Thomas Löning; Klaus Pantel; Sabine Riethdorf
Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression.
British journal of cancer 2011;104(1):138-45.
2011: Juliane Hannemann; Simon A Joosse; Dirk Kemming; Stefan Kurtz; Sönke Meyer-Staeckling; Klaus Pantel; Heike Pospisil; Klaus Püschel; Sabine Riethdorf; Iris Alpers; Jennifer Görndt; Burkhard Brandt
Quantitative high-resolution genomic analysis of single cancer cells.
PloS one 2011;6(11):e26362.
2011: Natalia Bednarz-Knoll; Catherine Alix-Panabières; Klaus Pantel
Clinical relevance and biology of circulating tumor cells.
Breast cancer research : BCR 2011;13(6):228.
2011: Volkmar Müller; Klaus Pantel; Brigitte Rack; Sabine Riethdorf; Erich Solomayer; Julia Zeitz; Bahriye Aktas; Peter A Fasching; Tanja Fehm; Wolfgang Janni; Sabine Kasimir-Bauer
Prospective evaluation of serum tissue inhibitor of metalloproteinase 1 and carbonic anhydrase IX in correlation to circulating tumor cells in patients with metastatic breast cancer.
Breast cancer research : BCR 2011;13(4):R71.
2011: Carina Roth; Klaus Pantel; Volkmar Müller; Brigitte Rack; Sabine Kasimir-Bauer; Wolfgang Janni; Heidi Schwarzenbach
Apoptosis-related deregulation of proteolytic activities and high serum levels of circulating nucleosomes and DNA in blood correlate with breast cancer progression.
BMC cancer 2011;11():4.
2010: Tanja Fehm; Volkmar Müller; Bahriye Aktas; Wolfgang Janni; Andreas Schneeweiss; Elmar Stickeler; Claus Lattrich; Christian R Löhberg; Erich Solomayer; Brigitte Rack; Sabine Riethdorf; Christoph Klein; Christian Schindlbeck; Kerstin Brocker; Sabine Kasimir-Bauer; Diethelm Wallwiener; Klaus Pantel
HER2 status of circulating tumor cells in patients with metastatic breast cancer: a prospective, multicenter trial.
Breast cancer research and treatment 2010;124(2):403-12.
2010: Tatyana Kalinina; Maximilian Bockhorn; Jussuf T Kaifi; Sabrina Thieltges; Cenap Güngör; Katharina E Effenberger; Andrea Strelow; Uta Reichelt; Guido Sauter; Klaus Pantel; Jakob R Izbicki; Emre F Yekebas
Insulin-like growth factor-1 receptor as a novel prognostic marker and its implication as a cotarget in the treatment of human adenocarcinoma of the esophagus.
International journal of cancer. Journal international du cancer 2010;127(8):1931-40.
2010: Sabine Riethdorf; Klaus Pantel
Advancing personalized cancer therapy by detection and characterization of circulating carcinoma cells.
Annals of the New York Academy of Sciences 2010;1210():66-77.
2010: Klaus Pantel; Catherine Alix-Panabières
Circulating tumour cells in cancer patients: challenges and perspectives.
Trends in molecular medicine 2010;16(9):398-406.
2010: Heidi Schwarzenbach; Eray Goekkurt; Klaus Pantel; Daniela E Aust; Jan Stoehlmacher
Molecular analysis of the polymorphisms of thymidylate synthase on cell-free circulating DNA in blood of patients with advanced colorectal carcinoma.
International journal of cancer. Journal international du cancer 2010;127(4):881-8.
2010: Natalia Bednarz; Elke Eltze; Axel Semjonow; Michael Rink; Antje Andreas; Lennart Mulder; Juliane Hannemann; Margit Fisch; Klaus Pantel; Heinz-Ulrich G Weier; Krzysztof Piotr Bielawski; Burkhard Brandt
BRCA1 loss preexisting in small subpopulations of prostate cancer is associated with advanced disease and metastatic spread to lymph nodes and peripheral blood.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(13):3340-8.
2010: Kai Bartkowiak; Katharina E Effenberger; Sönke Harder; Antje Andreas; Friedrich Buck; Jasna Peter-Katalinic; Klaus Pantel; Burkhard H Brandt
Discovery of a novel unfolded protein response phenotype of cancer stem/progenitor cells from the bone marrow of breast cancer patients.
Journal of proteome research 2010;9(6):3158-68.
2010: Sabine Riethdorf; Volkmar Müller; Liling Zhang; Thomas Rau; Sibylle Loibl; Martina Komor; Marc Roller; Jens Huober; Tanja Fehm; Iris Schrader; Jörn Hilfrich; Frank Holms; Hans Tesch; Holger Eidtmann; Michael Untch; Gunter von Minckwitz; Klaus Pantel
Detection and HER2 expression of circulating tumor cells: prospective monitoring in breast cancer patients treated in the neoadjuvant GeparQuattro trial.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(9):2634-45.
2010: Volkmar Müller; Catherine Alix-Panabières; Klaus Pantel
Insights into minimal residual disease in cancer patients: implications for anti-cancer therapies.
European journal of cancer (Oxford, England : 1990) 2010;46(7):1189-97.
2010: Carina Roth; Brigitte Rack; Volkmar Müller; Wolfgang Janni; Klaus Pantel; Heidi Schwarzenbach
Circulating microRNAs as blood-based markers for patients with primary and metastatic breast cancer.
Breast cancer research : BCR 2010;12(6):R90.
2010: Imke Müller; Frank Wischnewski; Klaus Pantel; Heidi Schwarzenbach
Promoter- and cell-specific epigenetic regulation of CD44, Cyclin D2, GLIPR1 and PTEN by methyl-CpG binding proteins and histone modifications.
BMC cancer 2010;10():297.
2009: Volkmar Müller; Klaus Pantel
HER2 as marker for the detection of circulating tumor cells.
Breast cancer research and treatment 2009;117(3):535-7.
2009: Klaus Pantel; Catherine Alix-Panabières; Sabine Riethdorf
Cancer micrometastases.
Nature reviews. Clinical oncology 2009;6(6):339-51.
2009: Kai Bartkowiak; Marek Wieczorek; Friedrich Buck; Sönke Harder; Jennifer Moldenhauer; Katharina E Effenberger; Klaus Pantel; Jasna Peter-Katalinic; Burkhard H Brandt
Two-dimensional differential gel electrophoresis of a cell line derived from a breast cancer micrometastasis revealed a stem/ progenitor cell protein profile.
Journal of proteome research 2009;8(4):2004-14.
2009: Klaus Pantel; Sabine Riethdorf
Pathology: are circulating tumor cells predictive of overall survival?
Nature reviews. Clinical oncology 2009;6(4):190-1.
2009: Michaela Wrage; Salla Ruosaari; Paul P Eijk; Jussuf T Kaifi; Jaakko Hollmén; Emre F Yekebas; Jakob R Izbicki; Ruud H Brakenhoff; Thomas Streichert; Sabine Riethdorf; Markus Glatzel; Bauke Ylstra; Klaus Pantel; Harriet Wikman
Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(5):1566-74.
2009: Heidi Schwarzenbach; Catherine Alix-Panabières; Imke Müller; Nicolas Letang; Jean-Pierre Vendrell; Xavier Rebillard; Klaus Pantel
Cell-free tumor DNA in blood plasma as a marker for circulating tumor cells in prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(3):1032-8.
2009: Alexandra M Koenig; Klaus L Prenzel; Dean Bogoevski; Emre F Yekebas; Michael Bubenheim; Lucia Faithova; Yogesh Vashist; Karim A Gawad; Stephan E Baldus; Klaus Pantel; Paul M Schneider; Arnulf H Hölscher; Jakob R Izbicki
Strong impact of micrometastatic tumor cell load in patients with esophageal carcinoma.
Annals of surgical oncology 2009;16(2):454-62.
2009: Sabine Riethdorf; Klaus Pantel
Clinical relevance and current challenges of research on disseminating tumor cells in cancer patients.
Breast cancer research : BCR 2009;11 Suppl 3():S10.
2009: Heidi Schwarzenbach; Klaus Pantel; Birthe Kemper; Cord Beeger; Friedrich Otterbach; Rainer Kimmig; Sabine Kasimir-Bauer
Comparative evaluation of cell-free tumor DNA in blood and disseminated tumor cells in bone marrow of patients with primary breast cancer.
Breast cancer research : BCR 2009;11(5):R71.
2009: Catherine Alix-Panabières; Jean-Pierre Vendrell; Monique Slijper; Olivier Pellé; Eric Barbotte; Grégoire Mercier; William Jacot; Michel Fabbro; Klaus Pantel
Full-length cytokeratin-19 is released by human tumor cells: a potential role in metastatic progression of breast cancer.
Breast cancer research : BCR 2009;11(3):R39.
2008: Sabine Riethdorf; Harriet Wikman; Klaus Pantel
Review: Biological relevance of disseminated tumor cells in cancer patients.
International journal of cancer. Journal international du cancer 2008;123(9):1991-2006.
2008: Jens Köllermann; Steffen Weikert; Martin Schostak; Carsten Kempkensteffen; Klaus Kleinschmidt; Thomas Rau; Klaus Pantel
Prognostic significance of disseminated tumor cells in the bone marrow of prostate cancer patients treated with neoadjuvant hormone treatment.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(30):4928-33.
2008: Catherine Alix-Panabières; Sabine Riethdorf; Klaus Pantel
Circulating tumor cells and bone marrow micrometastasis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(16):5013-21.
2008: Heidi Schwarzenbach; Jan Stoehlmacher; Klaus Pantel; Eray Goekkurt
Detection and monitoring of cell-free DNA in blood of patients with colorectal cancer.
Annals of the New York Academy of Sciences 2008;1137():190-6.
2008: Heidi Schwarzenbach; Felix K-H Chun; Imke Müller; Christoph Seidel; Karoline Urban; Andreas Erbersdobler; Hartwig Huland; Klaus Pantel; Martin G Friedrich
Microsatellite analysis of allelic imbalance in tumour and blood from patients with prostate cancer.
BJU international 2008;102(2):253-8.
2008: Sebastian Dango; Wulf Sienel; Moritz Schreiber; Christian Stremmel; Andreas Kirschbaum; Klaus Pantel; Bernward Passlick
Elevated expression of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM-1) is associated with increased angiogenic potential in non-small-cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2008;60(3):426-33.
2008: Klaus Pantel; Ruud H Brakenhoff; Burkhard Brandt
Detection, clinical relevance and specific biological properties of disseminating tumour cells.
Nature reviews. Cancer 2008;8(5):329-40.
2008: Imke Müller; Cord Beeger; Catherine Alix-Panabières; Xavier Rebillard; Klaus Pantel; Heidi Schwarzenbach
Identification of loss of heterozygosity on circulating free DNA in peripheral blood of prostate cancer patients: potential and technical improvements.
Clinical chemistry 2008;54(4):688-96.
2008: Tanja Fehm; Volkmar Müller; Catherine Alix-Panabières; Klaus Pantel
Micrometastatic spread in breast cancer: detection, molecular characterization and clinical relevance.
Breast cancer research : BCR 2008;10 Suppl 1():S1.
2008: Anne-Sofie Schrohl; Volkmar Mueller; Ib Jarle Christensen; Klaus Pantel; Christoph Thomssen; Nils Bruenner
A comparative study of tissue inhibitor of metalloproteinases-1 levels in plasma and tumour tissue from patients with primary breast cancer and in plasma from patients with metastatic breast cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2008;29(3):181-7.
2008: Sabine Riethdorf; Klaus Pantel
Disseminated tumor cells in bone marrow and circulating tumor cells in blood of breast cancer patients: current state of detection and characterization.
Pathobiology : journal of immunopathology, molecular and cellular biology 2008;75(2):140-8.
2007: Catherine Alix-Panabières; Volkmar Müller; Klaus Pantel
Current status in human breast cancer micrometastasis.
Current opinion in oncology 2007;19(6):558-63.
2007: Jussuf T Kaifi; Uta Reichelt; Alexander Quaas; Paulus G Schurr; Robin Wachowiak; Emre F Yekebas; Tim Strate; Claus Schneider; Klaus Pantel; Melitta Schachner; Guido Sauter; Jakob R Izbicki
L1 is associated with micrometastatic spread and poor outcome in colorectal cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007;20(11):1183-90.
2007: Robin Wachowiak; Jussuf T Kaifi; Heidi Schwarzenbach; Emre F Yekebas; Petra Merkert; Paulus G Schurr; Bente Hansen; Uta Reichelt; Tim Strate; Klaus Pantel; Jakob R Izbicki
Microsatellite analysis in serum DNA as a diagnostic tool for distinction of patients with unknown pancreatic masses.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2007;16(3):174-8.
2007: Jussuf T Kaifi; Tamina Rawnaq; Paulus G Schurr; Emre F Yekebas; Oliver Mann; Petra Merkert; Björn-Christian Link; Viacheslav Kalinin; Klaus Pantel; Guido Sauter; Tim Strate; Jakob R Izbicki
Short tandem repeat polymorphism in exon 4 of esophageal cancer-related gene 2 detected in genomic DNA is a prognostic marker for esophageal cancer.
American journal of surgery 2007;194(3):380-4.
2007: Frank Wischnewski; Olaf Friese; Klaus Pantel; Heidi Schwarzenbach
Methyl-CpG binding domain proteins and their involvement in the regulation of the MAGE-A1, MAGE-A2, MAGE-A3, and MAGE-A12 gene promoters.
Molecular cancer research : MCR 2007;5(7):749-59.
2007: Wulf Sienel; Ingo Mecklenburg; Sebastian Dango; Peter Ehrhardt; Andreas Kirschbaum; Bernward Passlick; Klaus Pantel
Detection of MAGE-A transcripts in bone marrow is an independent prognostic factor in operable non-small-cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(13):3840-7.
2007: Heidi Schwarzenbach; Felix K-H Chun; Imke Lange; Sebastian Carpenter; Miriam Gottberg; Andreas Erbersdobler; Martin G Friedrich; Hartwig Huland; Klaus Pantel
Detection of tumor-specific DNA in blood and bone marrow plasma from patients with prostate cancer.
International journal of cancer. Journal international du cancer 2007;120(7):1465-71.
2007: Catherine Alix-Panabières; Jean-Pierre Vendrell; Olivier Pellé; Xavier Rebillard; Sabine Riethdorf; Volkmar Müller; Michel Fabbro; Klaus Pantel
Detection and characterization of putative metastatic precursor cells in cancer patients.
Clinical chemistry 2007;53(3):537-9.
2007: Sabine Riethdorf; Herbert Fritsche; Volkmar Müller; Thomas Rau; Christian Schindlbeck; Brigitte Rack; Wolfgang Janni; Cornelia Coith; Katrin Beck; Fritz Jänicke; Summer Jackson; Terrie Gornet; Massimo Cristofanilli; Klaus Pantel
Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch system.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(3):920-8.
2007: Klaus Pantel; Catherine Alix-Panabières
The clinical significance of circulating tumor cells.
Nature clinical practice. Oncology 2007;4(2):62-3.
2007: Katharina E Effenberger; Wulf Sienel; Klaus Pantel
Lymph node micrometastases in lung cancer.
Cancer treatment and research 2007;135():167-75.
2007: Heidi Schwarzenbach; Volkmar Müller; Cord Beeger; Miriam Gottberg; Nicole Stahmann; Klaus Pantel
A critical evaluation of loss of heterozygosity detected in tumor tissues, blood serum and bone marrow plasma from patients with breast cancer.
Breast cancer research : BCR 2007;9(5):R66.
2007: Paulus G Schurr; Sophia Behnke; Jussuf T Kaifi; Dean Bogoevski; Bjoern Link; Oliver Mann; Tim Strate; Klaus Pantel; Jakob R Izbicki; Emre F Yekebas
Central mesenteric lymph node BER-Ep4+ cells in colorectal cancer: challenge to sentinel node concept?
Digestive surgery 2007;24(1):19-27.
2007: Sonja Loges; Henning Clausen; Uta Reichelt; Michael Bubenheim; Andreas Erbersdobler; Paulus G Schurr; Emre F Yekebas; Gunter Schuch; Jakob R Izbicki; Klaus Pantel; Carsten Bokemeyer; Walter Fiedler
Determination of microvessel density by quantitative real-time PCR in esophageal cancer: correlation with histologic methods, angiogenic growth factor expression, and lymph node metastasis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(1):76-80.
2006: Elin Borgen; Klaus Pantel; Günter Schlimok; P Müller; M Otte; A Renolen; S Ehnle; C Coith; Jahn M Nesland; Bjørn Naume
A European interlaboratory testing of three well-known procedures for immunocytochemical detection of epithelial cells in bone marrow. Results from analysis of normal bone marrow.
Cytometry. Part B, Clinical cytometry 2006;70(6):400-9.
2006: Emre F Yekebas; Dean Bogoevski; Michael Bubenheim; Björn-Christian Link; Jussuf T Kaifi; Robin Wachowiak; Oliver Mann; Asad Kutup; Guellue Cataldegirmen; Lars Wolfram; Andreas Erbersdobler; Christoph Klein; Klaus Pantel; Jakob R Izbicki
Strong prognostic value of nodal and bone marrow micro-involvement in patients with pancreatic ductal carcinoma receiving no adjuvant chemotherapy.
World journal of gastroenterology : WJG 2006;12(40):6515-21.
2006: Sabine Riethdorf; Natalie Reimers; Volker Assmann; Jan-Wilhelm Kornfeld; Luigi Terracciano; Guido Sauter; Klaus Pantel
High incidence of EMMPRIN expression in human tumors.
International journal of cancer. Journal international du cancer 2006;119(8):1800-10.
2006: Paulus G Schurr; Emre F Yekebas; Jussuf T Kaifi; Steffi Lasch; Tim Strate; Asad Kutup; Guellue Cataldegirmen; Michael Bubenheim; Klaus Pantel; Jakob R Izbicki
Lymphatic spread and microinvolvement in adenocarcinoma of the esophago-gastric junction.
Journal of surgical oncology 2006;94(4):307-15.
2006: Imke Müller; Karoline Urban; Klaus Pantel; Heidi Schwarzenbach
Comparison of genetic alterations detected in circulating microsatellite DNA in blood plasma samples of patients with prostate cancer and benign prostatic hyperplasia.
Annals of the New York Academy of Sciences 2006;1075():222-9.
2006: Felix K-H Chun; Imke Müller; Imke Lange; Martin G Friedrich; Andreas Erbersdobler; Pierre I Karakiewicz; Markus Graefen; Klaus Pantel; Hartwig Huland; Heidi Schwarzenbach
Circulating tumour-associated plasma DNA represents an independent and informative predictor of prostate cancer.
BJU international 2006;98(3):544-8.
2006: Tanja Fehm; Stephan Braun; Volkmar Muller; Wolfgang Janni; Gerhard Gebauer; Christian Marth; Christian Schindlbeck; Diethelm Wallwiener; Elin Borgen; Bjørn Naume; Klaus Pantel; Erich Solomayer
A concept for the standardized detection of disseminated tumor cells in bone marrow from patients with primary breast cancer and its clinical implementation.
Cancer 2006;107(5):885-92.
2006: Isabell Witzel; Christoph Thomssen; Sylke Krenkel; W Wilczak; Michael Bubenheim; Klaus Pantel; R Neumann; Fritz Jänicke; Volkmar Müller
Clinical utility of determination of HER-2/neu and EGFR fragments in serum of patients with metastatic breast cancer.
The International journal of biological markers 2006;21(3):131-40.
2006: Dave S B Hoon; Minoru Kitago; Joseph Kim; Takuji Mori; Adriano Piris; Katherine Szyfelbein; Martin C Mihm; S David Nathanson; Timothy P Padera; Ann F Chambers; sharon vantyghem; Ian C MacDonald; Steve Shivers; Marwan Alsarraj; Douglas S Reintgen; Bernward Passlick; Wulf Sienel; Klaus Pantel
Molecular mechanisms of metastasis.
Cancer metastasis reviews 2006;25(2):203-20.
2006: Frank Wischnewski; Klaus Pantel; Heidi Schwarzenbach
Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells.
Molecular cancer research : MCR 2006;4(5):339-49.
2006: Volkmar Müller; Isabell Witzel; Klaus Pantel; Sylke Krenkel; Hans-Joachim Lück; Rainer Neumann; Thomas Keller; Jürgen Dittmer; Fritz Jänicke; Christoph Thomssen
Prognostic and predictive impact of soluble epidermal growth factor receptor (sEGFR) protein in the serum of patients treated with chemotherapy for metastatic breast cancer.
Anticancer research 2006;26(2B):1479-87.
2006: Volkmar Müller; Daniel F Hayes; Klaus Pantel
Recent translational research: circulating tumor cells in breast cancer patients.
Breast cancer research : BCR 2006;8(5):110.
2005: Jussuf T Kaifi; Emre F Yekebas; Paulus G Schurr; Dennis Obonyo; Robin Wachowiak; Philipp Busch; Antje Heinecke; Klaus Pantel; Jakob R Izbicki
Tumor-cell homing to lymph nodes and bone marrow and CXCR4 expression in esophageal cancer.
Journal of the National Cancer Institute 2005;97(24):1840-7.
2005: Birthe Willipinski-Stapelfeldt; Sabine Riethdorf; Volker Assmann; Ute Woelfle; Thomas Rau; Guido Sauter; Jochen Heukeshoven; Klaus Pantel
Changes in cytoskeletal protein composition indicative of an epithelial-mesenchymal transition in human micrometastatic and primary breast carcinoma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(22):8006-14.
2005: Klaus Pantel; Ute Woelfle
Detection and molecular characterisation of disseminated tumour cells: implications for anti-cancer therapy.
Biochimica et biophysica acta 2005;1756(1):53-64.
2005: Stephan Braun; Florian D Vogl; Bjørn Naume; Wolfgang Janni; Michael P Osborne; R Charles Coombes; Günter Schlimok; Ingo J Diel; Bernd Gerber; Gerhard Gebauer; Jean-Yves Pierga; Christian Marth; Daniel Oruzio; Gro Wiedswang; Erich Solomayer; Günther Kundt; Barbara Strobl; Tanja Fehm; George Y C Wong; Judith Bliss; Anne Vincent-Salomon; Klaus Pantel
A pooled analysis of bone marrow micrometastasis in breast cancer.
The New England journal of medicine 2005;353(8):793-802.
2005: Volkmar Müller; Nicole Stahmann; Sabine Riethdorf; Thomas Rau; Tanja Zabel; Alexander Goetz; Fritz Jänicke; Klaus Pantel
Circulating tumor cells in breast cancer: correlation to bone marrow micrometastases, heterogeneous response to systemic therapy and low proliferative activity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(10):3678-85.
2005: Ute Woelfle; Elisabeth Breit; Kristine Zafrakas; Marcus Otte; Falk Schubert; Volkmar Müller; Jakob R Izbicki; Thomas Löning; Klaus Pantel
Bi-specific immunomagnetic enrichment of micrometastatic tumour cell clusters from bone marrow of cancer patients.
Journal of immunological methods 2005;300(1-2):136-45.
2005: Wolfgang Janni; Brigitte Rack; Christian Schindlbeck; Barbara Strobl; Dorothea Rjosk; Stephan Braun; Harald Sommer; Klaus Pantel; Bernd Gerber; Klaus Friese
The persistence of isolated tumor cells in bone marrow from patients with breast carcinoma predicts an increased risk for recurrence.
Cancer 2005;103(5):884-91.
2005: Volkmar Müller; Klaus Pantel
BM micrometastases and circulating tumor cells in breast cancer patients: where have we been, where are we now and where does the future lie?
Cytotherapy 2005;7(6):478-82.
2005: Michael Grimm; Pascal Haas; Birthe Willipinski-Stapelfeldt; Wolfram-Hubertus Zimmermann; Thomas Rau; Klaus Pantel; Michael Weyand; Thomas Eschenhagen
Key role of myosin light chain (MLC) kinase-mediated MLC2a phosphorylation in the alpha 1-adrenergic positive inotropic effect in human atrium.
Cardiovascular research 2005;65(1):211-20.
2004: Dean Bogoevski; Emre F Yekebas; Paulus G Schurr; Jussuf T Kaifi; Asad Kutup; Andreas Erbersdobler; Klaus Pantel; Jakob R Izbicki
Mode of spread in the early phase of lymphatic metastasis in pancreatic ductal adenocarcinoma: prognostic significance of nodal microinvolvement.
Annals of surgery 2004;240(6):993-1000; discussion 1000-1.
2004: Volkmar Müller; Isabell Witzel; Hans-Joachim Lück; Günter Köhler; Gunter von Minckwitz; Volker Möbus; Daniel Sattler; Waldemar Wilczak; Thomas Löning; Fritz Jänicke; Klaus Pantel; Christoph Thomssen
Prognostic and predictive impact of the HER-2/ neu extracellular domain (ECD) in the serum of patients treated with chemotherapy for metastatic breast cancer.
Breast cancer research and treatment 2004;86(1):9-18.
2004: Klaus Pantel; Ruud H Brakenhoff
Dissecting the metastatic cascade.
Nature reviews. Cancer 2004;4(6):448-56.
2004: Natalie Reimers; Kristine Zafrakas; Volker Assmann; Cornelia Egen; Lutz Riethdorf; Sabine Riethdorf; Jürgen Berger; Sebastian Ebel; Fritz Jänicke; Guido Sauter; Klaus Pantel
Expression of extracellular matrix metalloproteases inducer on micrometastatic and primary mammary carcinoma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(10):3422-8.
2004: Ute Woelfle; Guido Sauter; Sonja Santjer; Ruud H Brakenhoff; Klaus Pantel
Down-regulated expression of cytokeratin 18 promotes progression of human breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(8):2670-4.
2004: Klaus Pantel; Ute Woelfle
Micrometastasis in breast cancer and other solid tumors.
Journal of biological regulators and homeostatic agents 2004;18(2):120-5.
2004: Volkmar Müller; Klaus Pantel
Bone marrow micrometastases and circulating tumor cells: current aspects and future perspectives.
Breast cancer research : BCR 2004;6(6):258-61.
2003: Alice Hemsen; Lutz Riethdorf; Nils Brünner; Jürgen Berger; Sebastian Ebel; Christoph Thomssen; Fritz Jänicke; Klaus Pantel
Comparative evaluation of urokinase-type plasminogen activator receptor expression in primary breast carcinomas and on metastatic tumor cells.
International journal of cancer. Journal international du cancer 2003;107(6):903-9.
2003: Klaus Pantel; Volkmar Müller; Margherita Auer; Nathalie Nusser; Nadia Harbeck; Stephan Braun
Detection and clinical implications of early systemic tumor cell dissemination in breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(17):6326-34.
2003: Stephan Braun; Florian D Vogl; Wolfgang Janni; Christian Marth; Günter Schlimok; Klaus Pantel
Evaluation of bone marrow in breast cancer patients: prediction of clinical outcome and response to therapy.
Breast (Edinburgh, Scotland) 2003;12(6):397-404.
2003: Martin G Friedrich; M I Toma; Angelika Hellstern; Klaus Pantel; Daniel J Weisenberger; Joachim Noldus; Hartwig Huland
Comparison of multitarget fluorescence in situ hybridization in urine with other noninvasive tests for detecting bladder cancer.
BJU international 2003;92(9):911-4.
2003: Jens Köllermann; Markus Müller; Carsten Goessl; Hans Krause; Burkhard Helpap; Klaus Pantel; Kurt Miller
Methylation-specific PCR for DNA-based detection of occult tumor cells in lymph nodes of prostate cancer patients.
European urology 2003;44(5):533-8.
2003: Ute Woelfle; Jacqueline Cloos; Guido Sauter; Lutz Riethdorf; Fritz Jänicke; Paulus van Diest; Ruud H Brakenhoff; Klaus Pantel
Molecular signature associated with bone marrow micrometastasis in human breast cancer.
Cancer research 2003;63(18):5679-84.
2003: Holger Thurm; Sebastian Ebel; Christina Kentenich; Alice Hemsen; Sabine Riethdorf; Cornelia Coith; Diethelm Wallwiener; Stephan Braun; Carsten Oberhoff; Fritz Jänicke; Klaus Pantel
Rare expression of epithelial cell adhesion molecule on residual micrometastatic breast cancer cells after adjuvant chemotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(7):2598-604.
2003: Wulf Sienel; Sebastian Dango; Ute Woelfle; Alicia Morresi-Hauf; Christoph Wagener; Jens Brümmer; Wolf Mutschler; Bernward Passlick; Klaus Pantel
Elevated expression of carcinoembryonic antigen-related cell adhesion molecule 1 promotes progression of non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(6):2260-6.
2003: Susanna Hegewisch-Becker; Katharina Braun; Markus Otte; Aneta Corovic; Djordje Atanackovic; Axel Nierhaus; Dieter K Hossfeld; Klaus Pantel
Effects of whole body hyperthermia (41.8 degrees C) on the frequency of tumor cells in the peripheral blood of patients with advanced malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(6):2079-84.
2003: Wulf Sienel; Rita Seen-Hibler; Wolf Mutschler; Klaus Pantel; Bernward Passlick
Tumour cells in the tumour draining vein of patients with non-small cell lung cancer: detection rate and clinical significance.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2003;23(4):451-6.
2003: Wulf Sienel; Joe Hellers; Alicia Morresi-Hauf; Ralf Lichtinghagen; Wolf Mutschler; Marianne Jochum; Christoph Klein; Bernward Passlick; Klaus Pantel
Prognostic impact of matrix metalloproteinase-9 in operable non-small cell lung cancer.
International journal of cancer. Journal international du cancer 2003;103(5):647-51.
2003: Wolfgang Janni; Florian Hepp; Barbara Strobl; Brigitte Rack; Dorothea Rjosk; Christina Kentenich; Christian Schindlbeck; Peer Hantschmann; Klaus Pantel; Harald Sommer; Stephan Braun
Patterns of disease recurrence influenced by hematogenous tumor cell dissemination in patients with cervical carcinoma of the uterus.
Cancer 2003;97(2):405-11.
2003: Volkmar Müller; Christoph Thomssen; C Karakas; I Eustermann; J Ramirez Porras; Cornelia Coith; J Berger; T Löning; Fritz Jänicke; Klaus Pantel
Quantitative assessment of HER-2/neu protein concentration in breast cancer by enzyme-linked immunosorbent assay.
The International journal of biological markers 2003;18(1):13-20.
2002: Bernward Passlick; B Kubuschock; Wulf Sienel; Olaf Thetter; Klaus Pantel; Jakob R Izbicki
Mediastinal lymphadenectomy in non-small cell lung cancer: effectiveness in patients with or without nodal micrometastases - results of a preliminary study.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2002;21(3):520-6.
2002: Peter Kufer; Alfred Zippelius; Ralf Lutterbüse; Ingo Mecklenburg; Thomas Enzmann; Anthony Montag; Dorothea Weckermann; Bernward Passlick; Nadja Prang; Peter Reichardt; Martin Dugas; Manfred W Köllermann; Klaus Pantel; Gert Riethmüller
Heterogeneous expression of MAGE-A genes in occult disseminated tumor cells: a novel multimarker reverse transcription-polymerase chain reaction for diagnosis of micrometastatic disease.
Cancer research 2002;62(1):251-61.
2001: Klaus Pantel; Markus Otte
Occult micrometastasis: enrichment, identification and characterization of single disseminated tumour cells.
Seminars in cancer biology 2001;11(5):327-37.
2001: Markus Otte; M Zafrakas; Lutz Riethdorf; U Pichlmeier; T Löning; Fritz Jänicke; Klaus Pantel
MAGE-A gene expression pattern in primary breast cancer.
Cancer research 2001;61(18):6682-7.
2001: Konstantin Maletz; Peter Kufer; Matthias Mack; Tobias Raum; Klaus Pantel; Gert Riethmüller; R Gruber
Bispecific single-chain antibodies as effective tools for eliminating epithelial cancer cells from human stem cell preparations by redirected cell cytotoxicity.
International journal of cancer. Journal international du cancer 2001;93(3):409-16.
2001: Wolfgang Janni; Florian Hepp; Dorothea Rjosk; Christina Kentenich; Barbara Strobl; Christian Schindlbeck; Peer Hantschmann; Harald Sommer; Klaus Pantel; Stephan Braun
The fate and prognostic value of occult metastatic cells in the bone marrow of patients with breast carcinoma between primary treatment and recurrence.
Cancer 2001;92(1):46-53.
2001: Stephan Braun; Christian Schindlbeck; Florian Hepp; Wolfgang Janni; Christina Kentenich; Gert Riethmüller; Klaus Pantel
Occult tumor cells in bone marrow of patients with locoregionally restricted ovarian cancer predict early distant metastatic relapse.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(2):368-75.
2000: Bernward Passlick; Wulf Sienel; Rita Seen-Hibler; W Wöckel; Olaf Thetter; Wolf Mutschler; Klaus Pantel
Overexpression of matrix metalloproteinase 2 predicts unfavorable outcome in early-stage non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(10):3944-8.
2000: Bernward Passlick; Wulf Sienel; Rita Seen-Hibler; W Wöckel; Olaf Thetter; Klaus Pantel
The 17-1A antigen is expressed on primary, metastatic and disseminated non-small cell lung carcinoma cells.
International journal of cancer. Journal international du cancer 2000;87(4):548-52.
2000: Bernward Passlick; B Kubuschok; Jakob R Izbicki; Olaf Thetter; Klaus Pantel
[Isolated tumor cells in bone marrow predicts reduced survival in lymph node-negative non-small-cell lung cancer].
Pneumologie (Stuttgart, Germany) 2000;54(8):355-60.
2000: Alfred Zippelius; Ralf Lutterbüse; Gert Riethmüller; Klaus Pantel
Analytical variables of reverse transcription-polymerase chain reaction-based detection of disseminated prostate cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(7):2741-50.
2000: Stephan Braun; Klaus Pantel; P Müller; Wolfgang Janni; Florian Hepp; Christina Kentenich; S Gastroph; A Wischnik; Thomas Dimpfl; Günther Kindermann; Gert Riethmüller; Günter Schlimok
Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer.
The New England journal of medicine 2000;342(8):525-33.
2000: Klaus Pantel; M von Knebel Doeberitz
Detection and clinical relevance of micrometastatic cancer cells.
Current opinion in oncology 2000;12(1):95-101.
2000: Stephan Braun; Christina Kentenich; Wolfgang Janni; Florian Hepp; JC de Waal; Fritz Willgeroth; Harald Sommer; Klaus Pantel
Lack of effect of adjuvant chemotherapy on the elimination of single dormant tumor cells in bone marrow of high-risk breast cancer patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(1):80-6.
1999: Stephan Braun; Florian Hepp; Christina Kentenich; Wolfgang Janni; Klaus Pantel; Gert Riethmüller; Fritz Willgeroth; Harald Sommer
Monoclonal antibody therapy with edrecolomab in breast cancer patients: monitoring of elimination of disseminated cytokeratin-positive tumor cells in bone marrow.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(12):3999-4004.
1999: Bernward Passlick; B Kubuschok; Jakob R Izbicki; Olaf Thetter; Klaus Pantel
Isolated tumor cells in bone marrow predict reduced survival in node-negative non-small cell lung cancer.
The Annals of thoracic surgery 1999;68(6):2053-8.
1999: Stephan Braun; Klaus Pantel
Micrometastatic bone marrow involvement: detection and prognostic significance.
Medical oncology (Northwood, London, England) 1999;16(3):154-65.
1999: Gert Riethmüller; Christoph A Klein; Klaus Pantel
Hunting down the seminal cells of clinical metastases.
Immunology today 1999;20(7):294-6.
1999: Sonja Offner; W Schmaus; Klaus Witter; G B Baretton; Günter Schlimok; Bernward Passlick; Gert Riethmüller; Klaus Pantel
p53 gene mutations are not required for early dissemination of cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6942-6.
1999: Jens Köllermann; B Heseding; Burkhard Helpap; Manfred W Köllermann; Klaus Pantel
Comparative immunocytochemical assessment of isolated carcinoma cells in lymph nodes and bone marrow of patients with clinically localized prostate cancer.
International journal of cancer. Journal international du cancer 1999;84(2):145-9.
1999: Christoph A Klein; Oleg Schmidt-Kittler; Julian A Schardt; Klaus Pantel; Michael R Speicher; Gert Riethmüller
Comparative genomic hybridization, loss of heterozygosity, and DNA sequence analysis of single cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(8):4494-9.
1999: Stephan Braun; Florian Hepp; Harald Sommer; Klaus Pantel
Tumor-antigen heterogeneity of disseminated breast cancer cells: implications for immunotherapy of minimal residual disease.
International journal of cancer. Journal international du cancer 1999;84(1):1-5.
1999: Elin Borgen; Bjørn Naume; Jahn M Nesland; Gunnar Kvalheim; K Beiske; Oystein Fodstad; I Diel; Erich Solomayer; P Theocharous; R C Coombes; B M Smith; E Wunder; J P Marolleau; J Garcia; Klaus Pantel
Standardization of the immunocytochemical detection of cancer cells in BM and blood: I. establishment of objective criteria for the evaluation of immunostained cells.
Cytotherapy 1999;1(5):377-88.
1999: Stephan Braun; Klaus Pantel
Biological characteristics of micrometastatic cancer cells in bone marrow.
Cancer metastasis reviews 1999;18(1):75-90.
1999: B Kubuschok; Bernward Passlick; Jakob R Izbicki; Olaf Thetter; Klaus Pantel
Disseminated tumor cells in lymph nodes as a determinant for survival in surgically resected non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(1):19-24.
1999: E Putz; Klaus Witter; Sonja Offner; P Stosiek; Alfred Zippelius; J Johnson; R Zahn; Gert Riethmüller; Klaus Pantel
Phenotypic characteristics of cell lines derived from disseminated cancer cells in bone marrow of patients with solid epithelial tumors: establishment of working models for human micrometastases.
Cancer research 1999;59(1):241-8.
1998: Manfred W Köllermann; Klaus Pantel; Thomas Enzmann; U Feek; Jens Köllermann; M Kossiwakis; U Kaulfuss; W Martell; J Spitz
Supersensitive PSA-monitored neoadjuvant hormone treatment of clinically localized prostate cancer: effects on positive margins, tumor detection and epithelial cells in bone marrow.
European urology 1998;34(4):318-24.
1998: Stephan Braun; M Müller; Florian Hepp; Günter Schlimok; Gert Riethmüller; Klaus Pantel
Re: Micrometastatic breast cancer cells in bone marrow at primary surgery: prognostic value in comparison with nodal status.
Journal of the National Cancer Institute 1998;90(14):1099-101.
1998: Klaus Pantel; Bernward Passlick; J Vogt; P Stosiek; Matthias W A Angstwurm; Rita Seen-Hibler; Karl Häußinger; Olaf Thetter; Jakob R Izbicki; Gert Riethmüller
Reduced expression of plakoglobin indicates an unfavorable prognosis in subsets of patients with non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(4):1407-13.
1998: Bernward Passlick; Klaus Pantel; B Kubuschok; Jakob R Izbicki; Olaf Thetter
[Simultaneous immunocytochemical detection of tumor cells in lymph nodes and in bone marrow of patients with resectable bronchial carcinomas].
Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress 1998;115(Suppl I):21-4.
1998: Stephan Braun; Klaus Pantel
Prognostic significance of micrometastatic bone marrow involvement.
Breast cancer research and treatment 1998;52(1-3):201-16.
1998: Jakob R Izbicki; Bernward Passlick; Klaus Pantel; U Pichlmeier; Stefan B Hosch; Ortrud Karg; Olaf Thetter
Effectiveness of radical systematic mediastinal lymphadenectomy in patients with resectable non-small cell lung cancer: results of a prospective randomized trial.
Annals of surgery 1998;227(1):138-44.
1997: Klaus Pantel; M von Knebel Doeberitz; J R Izbicki; G Riethmüller
[Disseminated tumor cells: diagnosis, prognostic relevance, phenotyping and therapeutic strategies].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 1997;68(12):1241-50.
1997: Alfred Zippelius; Peter Kufer; G Honold; Manfred W Köllermann; Ralph Oberneder; Günter Schlimok; Gert Riethmüller; Klaus Pantel
Limitations of reverse-transcriptase polymerase chain reaction analyses for detection of micrometastatic epithelial cancer cells in bone marrow.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(7):2701-8.
1997: Klaus Pantel; Thomas Enzmann; Jens Köllermann; Jörg Caprano; Gert Riethmüller; Manfred W Köllermann
Immunocytochemical monitoring of micrometastatic disease: reduction of prostate cancer cells in bone marrow by androgen deprivation.
International journal of cancer. Journal international du cancer 1997;71(4):521-5.
1997: W Höchtlen-Vollmar; R Gruber; H Bodenmüller; E Felber; F Lindemann; Bernward Passlick; Günter Schlimok; Klaus Pantel; Gert Riethmüller
Occult epithelial tumor cells detected in bone marrow by an enzyme immunoassay specific for cytokeratin 19.
International journal of cancer. Journal international du cancer 1997;70(4):396-400.
1996: Stefan Thorban; Jürgen D Roder; H Nekarda; A Funk; Jörg Rüdiger Siewert; Klaus Pantel
Immunocytochemical detection of disseminated tumor cells in the bone marrow of patients with esophageal carcinoma.
Journal of the National Cancer Institute 1996;88(17):1222-7.
1996: Stefan Thorban; Jürgen D Roder; Klaus Pantel; Jörg Rüdiger Siewert
Immunocytochemical detection of isolated epithelial tumor cells in bone marrow of patients with pancreatic carcinoma.
American journal of surgery 1996;172(3):297-8.
1996: Jakob R Izbicki; Bernward Passlick; Stefan B Hosch; B Kubuschock; C Schneider; C Busch; Wolfram T Knoefel; Olaf Thetter; Klaus Pantel
Mode of spread in the early phase of lymphatic metastasis in non-small-cell lung cancer: significance of nodal micrometastasis.
The Journal of thoracic and cardiovascular surgery 1996;112(3):623-30.
1996: Klaus Pantel
Detection of minimal disease in patients with solid tumors.
Journal of hematotherapy 1996;5(4):359-67.
1996: Stefan Thorban; Jürgen D Roder; H Nekarda; A Funk; Klaus Pantel; Jörg Rüdiger Siewert
Disseminated epithelial tumor cells in bone marrow of patients with esophageal cancer: detection and prognostic significance.
World journal of surgery 1996;20(5):567-72; discussion 572-3.
1996: Karl-Walter Jauch; Markus M Heiss; U Gruetzner; Ilona Funke; Klaus Pantel; Rudolf Babic; H J Eissner; G Riethmueller; F W Schildberg
Prognostic significance of bone marrow micrometastases in patients with gastric cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(6):1810-7.
1996: Klaus Pantel; Jakob R Izbicki; Bernward Passlick; Matthias W A Angstwurm; Karl Häußinger; Olaf Thetter; Gert Riethmüller
Frequency and prognostic significance of isolated tumour cells in bone marrow of patients with non-small-cell lung cancer without overt metastases.
Lancet 1996;347(9002):649-53.
1996: Stefan Thorban; Jürgen D Roder; Klaus Pantel; Jörg Rüdiger Siewert
Epithelial tumour cells in bone marrow of patients with pancreatic carcinoma detected by immunocytochemical staining.
European journal of cancer (Oxford, England : 1990) 1996;32A(2):363-5.
1996: Bernward Passlick; Klaus Pantel; P Stosiek; Stefan B Hosch; Olaf Thetter; Jakob R Izbicki
[Expression of plakoglobin in bronchial carcinomas: incidence and significance for disease outcome].
Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress 1996;113():810-3.
1996: Bernward Passlick; Klaus Pantel
[Prognostic factors in stage I of non-small-cell bronchial carcinoma].
Zentralblatt für Chirurgie 1996;121(10):851-7; discussion 858-60.
1996: Stefan Thorban; Jürgen D Roder; Klaus Pantel; Jörg Rüdiger Siewert
[Immunocytochemical detection and prognostic significance of epithelial tumor cells in bone marrow of patients with pancreatic carcinoma].
Zentralblatt für Chirurgie 1996;121(6):487-9; discussion 490-2.
1996: Klaus Pantel; S Braun; Bernward Passlick; Günter Schlimok
Minimal residual epithelial cancer: diagnostic approaches and prognostic relevance.
Progress in histochemistry and cytochemistry 1996;30(3):1-60.
1996: Bernward Passlick; Klaus Pantel; B Kubuschok; Matthias W A Angstwurm; Albert Neher; Olaf Thetter; Leonhard Schweiberer; Jakob R Izbicki
Expression of MHC molecules and ICAM-1 on non-small cell lung carcinomas: association with early lymphatic spread of tumour cells.
European journal of cancer (Oxford, England : 1990) 1996;32A(1):141-5.
1996: Bernward Passlick; Jakob R Izbicki; B Kubuschok; Olaf Thetter; Klaus Pantel
Detection of disseminated lung cancer cells in lymph nodes: impact on staging and prognosis.
The Annals of thoracic surgery 1996;61(1):177-82; discussion 183.
1995: Hans Joachim Gath; E Heissler; Berthold Hell; Jürgen Bier; G Riethmüller; Klaus Pantel
Immunocytologic detection of isolated tumor cells in bone marrow of patients with squamous cell carcinomas of the head and neck region.
International journal of oral and maxillofacial surgery 1995;24(5):351-5.
1995: Klaus Pantel; C Aignherr; Jens Köllermann; J Caprano; Gert Riethmüller; Manfred W Köllermann
Immunocytochemical detection of isolated tumour cells in bone marrow of patients with untreated stage C prostatic cancer.
European journal of cancer (Oxford, England : 1990) 1995;31A(10):1627-32.
1995: Klaus Pantel; A Dickmanns; Alfred Zippelius; C Klein; J Shi; W Hoechtlen-Vollmar; Günter Schlimok; Dorothea Weckermann; Ralph Oberneder; Ellen Fanning
Establishment of micrometastatic carcinoma cell lines: a novel source of tumor cell vaccines.
Journal of the National Cancer Institute 1995;87(15):1162-8.
1995: Bernward Passlick; Olaf Thetter; Klaus Pantel; B Kubuschok; Uwe Pichlmeier; Leonhard Schweiberer; Jakob R Izbicki
[The significance of regional lymphatic tumor cell dissemination in patients with resectable non-small cell bronchial carcinoma. Results of a prospective study].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 1995;66(8):780-5; discussion 785-6.
1995: Klaus Pantel; Hans Joachim Gath; E Heissler
Staging of head and neck cancer.
The New England journal of medicine 1995;332(26):1788; author reply 1789-90.
1995: Bernward Passlick; Jakob R Izbicki; Karl Häußinger; Olaf Thetter; Klaus Pantel
Immunohistochemical detection of P53 protein is not associated with a poor prognosis in non-small-cell lung cancer.
The Journal of thoracic and cardiovascular surgery 1995;109(6):1205-11.
1995: Stephan Braun; Klaus Pantel
Immunodiagnosis and immunotherapy of isolated tumor cells disseminated to bone marrow of patients with colorectal cancer.
Tumori 1995;81(3 Suppl):78-83.
1995: Jakob R Izbicki; Bernward Passlick; Ortrud Karg; Christian Bloechle; Klaus Pantel; Wolfram T Knoefel; Olaf Thetter
Impact of radical systematic mediastinal lymphadenectomy on tumor staging in lung cancer.
The Annals of thoracic surgery 1995;59(1):209-14.
1995: Klaus Pantel; Günter Schlimok; Matthias W A Angstwurm; Bernward Passlick; Jakob R Izbicki; Judith P Johnson; Gert Riethmüller
Early metastasis of human solid tumours: expression of cell adhesion molecules.
Ciba Foundation symposium 1995;189():157-70; discussion 170-3, 174-6.
1994: Bernward Passlick; Jakob R Izbicki; B Kubuschok; W Nathrath; Olaf Thetter; Uwe Pichlmeier; Leonhard Schweiberer; Gert Riethmüller; Klaus Pantel
Immunohistochemical assessment of individual tumor cells in lymph nodes of patients with non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(9):1827-32.
1994: Jakob R Izbicki; Olaf Thetter; M Habekost; Ortrud Karg; Bernward Passlick; B Kubuschok; C Busch; Karl Häußinger; Wolfram T Knoefel; Klaus Pantel
Radical systematic mediastinal lymphadenectomy in non-small cell lung cancer: a randomized controlled trial.
The British journal of surgery 1994;81(2):229-35.
1994: Bernward Passlick; Jakob R Izbicki; S Simmel; B Kubuschok; Ortrud Karg; M Habekost; Olaf Thetter; Leonhard Schweiberer; Klaus Pantel
Expression of major histocompatibility class I and class II antigens and intercellular adhesion molecule-1 on operable non-small cell lung carcinomas: frequency and prognostic significance.
European journal of cancer (Oxford, England : 1990) 1994;30A(3):376-81.
1994: Klaus Pantel; E Felber; Günter Schlimok
Detection and characterization of residual disease in breast cancer.
Journal of hematotherapy 1994;3(4):315-22.
1994: Klaus Pantel; Günter Schlimok; Matthias W A Angstwurm; Dorothea Weckermann; W Schmaus; Hans Joachim Gath; Bernward Passlick; Jakob R Izbicki; Gert Riethmüller
Methodological analysis of immunocytochemical screening for disseminated epithelial tumor cells in bone marrow.
Journal of hematotherapy 1994;3(3):165-73.
1994: Ralph Oberneder; Rainer Riesenberg; Martin Kriegmair; U Bitzer; R Klammert; P Schneede; Alfons Hofstetter; Gert Riethmüller; Klaus Pantel
Immunocytochemical detection and phenotypic characterization of micrometastatic tumour cells in bone marrow of patients with prostate cancer.
Urological research 1994;22(1):3-8.
1993: Klaus Pantel; Günter Schlimok; S Braun; D Kutter; F Lindemann; G Schaller; Ilona Funke; J R Izbicki; Gert Riethmüller
Differential expression of proliferation-associated molecules in individual micrometastatic carcinoma cells.
Journal of the National Cancer Institute 1993;85(17):1419-24.
1993: Klaus Pantel; Jakob R Izbicki; Matthias W A Angstwurm; S Braun; Bernward Passlick; Ortrud Karg; Olaf Thetter; Gert Riethmüller
Immunocytological detection of bone marrow micrometastasis in operable non-small cell lung cancer.
Cancer research 1993;53(5):1027-31.
1993: Rainer Riesenberg; Ralph Oberneder; Martin Kriegmair; M Epp; U Bitzer; Alfons Hofstetter; S Braun; Gert Riethmüller; Klaus Pantel
Immunocytochemical double staining of cytokeratin and prostate specific antigen in individual prostatic tumour cells.
Histochemistry 1993;99(1):61-6.
1992: Gert Riethmüller; Günter Schlimok; Klaus Pantel; Matthias W A Angstwurm; Jakob R Izbicki; Ortrud Karg; B G Stade; Judith P Johnson
Metastasis formation in human solid tumors: phenotypic characteristics of early metastatic cells.
Behring Institute Mitteilungen 1992;(91):204-9.
1991: Klaus Pantel; Günter Schlimok; D Kutter; G Schaller; T Genz; B Wiebecke; R Backmann; Ilona Funke; Gert Riethmüller
Frequent down-regulation of major histocompatibility class I antigen expression on individual micrometastatic carcinoma cells.
Cancer research 1991;51(17):4712-5.
1991: Günter Schlimok; Ilona Funke; Klaus Pantel; F Strobel; F Lindemann; Jens Witte; Gert Riethmüller
Micrometastatic tumour cells in bone marrow of patients with gastric cancer: methodological aspects of detection and prognostic significance.
European journal of cancer (Oxford, England : 1990) 1991;27(11):1461-5.