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Uwe Panten

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Michael Willenborg; Kathrin Hatlapatka; Hany Ghaly; Michael Belz; Uwe Panten; Ingo Rustenbeck
Studies of first phase insulin secretion using imposed plasma membrane depolarization.
M Willenborg; H Ghaly; K Hatlapatka; K Urban; Uwe Panten; Ingo Rustenbeck
The signalling role of action potential depolarization in insulin secretion: metabolism-dependent dissociation between action potential increase and secretion increase by TEA.
Michael Willenborg; Uwe Panten; Ingo Rustenbeck
Triggering and amplification of insulin secretion by dimethyl alpha-ketoglutarate, a membrane permeable alpha-ketoglutarate analogue.

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All Publications

2011: Michael Willenborg; Kathrin Hatlapatka; Hany Ghaly; Michael Belz; Uwe Panten; Ingo Rustenbeck
Studies of first phase insulin secretion using imposed plasma membrane depolarization.
Frontiers in bioscience (Scholar edition) 2011;3():662-79.
2010: M Willenborg; H Ghaly; K Hatlapatka; K Urban; Uwe Panten; Ingo Rustenbeck
The signalling role of action potential depolarization in insulin secretion: metabolism-dependent dissociation between action potential increase and secretion increase by TEA.
Biochemical pharmacology 2010;80(1):104-12.
2009: Michael Willenborg; Uwe Panten; Ingo Rustenbeck
Triggering and amplification of insulin secretion by dimethyl alpha-ketoglutarate, a membrane permeable alpha-ketoglutarate analogue.
European journal of pharmacology 2009;607(1-3):41-6.
2008: Uwe Panten; Ingo Rustenbeck
Fuel-induced amplification of insulin secretion in mouse pancreatic islets exposed to a high sulfonylurea concentration: role of the NADPH/NADP+ ratio.
Diabetologia 2008;51(1):101-9.
2005: K A Urban; Uwe Panten
Selective loss of glucose-induced amplification of insulin secretion in mouse pancreatic islets pretreated with sulfonylurea in the absence of fuels.
Diabetologia 2005;48(12):2563-6.
2005: Henrike Heissig; Karin A Urban; Katja Hastedt; Bernd J Zünkler; Uwe Panten
Mechanism of the insulin-releasing action of alpha-ketoisocaproate and related alpha-keto acid anions.
Molecular pharmacology 2005;68(4):1097-105.
2004: Bernd J Zünkler; Maria Wos-Maganga; Uwe Panten
Fluorescence microscopy studies with a fluorescent glibenclamide derivative, a high-affinity blocker of pancreatic beta-cell ATP-sensitive K+ currents.
Biochemical pharmacology 2004;67(8):1437-44.
2003: Katja Hastedt; Uwe Panten
Inhibition of ATP-sensitive K(+)-channels by a sulfonylurea analogue with a phosphate group.
Biochemical pharmacology 2003;65(4):599-602.
1999: M Meyer; F Chudziak; Christina Schwanstecher; Mathias Schwanstecher; Uwe Panten
Structural requirements of sulphonylureas and analogues for interaction with sulphonylurea receptor subtypes.
British journal of pharmacology 1999;128(1):27-34.
1999: Mathias Schwanstecher; Christina Schwanstecher; F Chudziak; Uwe Panten; JP Clement; María Tinaquero; Lydia Aguilar-Bryan; Joseph Bryan
ATP-sensitive potassium channels.
Methods in enzymology 1999;294():445-58.
1998: Christina Schwanstecher; M Meyer; Mathias Schwanstecher; Uwe Panten
Interaction of N-benzoyl-D-phenylalanine and related compounds with the sulphonylurea receptor of beta-cells.
British journal of pharmacology 1998;123(6):1023-30.
1997: JP Clement; Kumud Kunjilwar; María Tinaquero; Mathias Schwanstecher; Uwe Panten; Lydia Aguilar-Bryan; Joseph Bryan
Association and stoichiometry of K(ATP) channel subunits.
Neuron 1997;18(5):827-38.
1996: Uwe Panten; Mathias Schwanstecher; Christina Schwanstecher
Sulfonylurea receptors and mechanism of sulfonylurea action.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1996;104(1):1-9.
1995: R H Chow; P E Lund; S Löser; Uwe Panten; E Gylfe
Coincidence of early glucose-induced depolarization with lowering of cytoplasmic Ca2+ in mouse pancreatic beta-cells.
The Journal of physiology 1995;485 ( Pt 3)():607-17.
1995: Mathias Schwanstecher; C Bachmann; S Löser; Uwe Panten
Interaction of fluorescein derivatives with sulfonylurea binding in insulin-secreting cells.
Pharmacology 1995;50(3):182-91.
1994: Mathias Schwanstecher; Christina Schwanstecher; C Dickel; F Chudziak; A Moshiri; Uwe Panten
Location of the sulphonylurea receptor at the cytoplasmic face of the beta-cell membrane.
British journal of pharmacology 1994;113(3):903-11.
1994: Mathias Schwanstecher; S Löser; F Chudziak; C Bachmann; Uwe Panten
Photoaffinity labeling of the cerebral sulfonylurea receptor using a novel radioiodinated azidoglibenclamide analogue.
Journal of neurochemistry 1994;63(2):698-708.
1994: Mathias Schwanstecher; K Mnner; Uwe Panten
Inhibition of K+ channels and stimulation of insulin secretion by the sulfonylurea, glimepiride, in relation to its membrane binding in pancreatic islets.
Pharmacology 1994;49(2):105-11.
1994: Mathias Schwanstecher; S Löser; F Chudziak; Uwe Panten
Identification of a 38-kDa high affinity sulfonylurea-binding peptide in insulin-secreting cells and cerebral cortex.
The Journal of biological chemistry 1994;269(27):17768-71.
1994: Christina Schwanstecher; Uwe Panten
Identification of an ATP-sensitive K+ channel in spiny neurons of rat caudate nucleus.
Pflügers Archiv : European journal of physiology 1994;427(1-2):187-9.
1994: Christina Schwanstecher; C Dickel; Uwe Panten
Interaction of tolbutamide and cytosolic nucleotides in controlling the ATP-sensitive K+ channel in mouse beta-cells.
British journal of pharmacology 1994;111(1):302-10.
1993: Christina Schwanstecher; Uwe Panten
Tolbutamide- and diazoxide-sensitive K+ channel in neurons of substantia nigra pars reticulata.
Naunyn-Schmiedeberg's archives of pharmacology 1993;348(1):113-7.
1992: Uwe Panten; Mathias Schwanstecher; Christina Schwanstecher
Pancreatic and extrapancreatic sulfonylurea receptors.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1992;24(12):549-54.
1992: Mathias Schwanstecher; U Schaupp; S Löser; Uwe Panten
The binding properties of the particulate and solubilized sulfonylurea receptor from cerebral cortex are modulated by the Mg2+ complex of ATP.
Journal of neurochemistry 1992;59(4):1325-35.
1992: Christina Schwanstecher; C Dickel; I Ebers; S Lins; B J Zünkler; Uwe Panten
Diazoxide-sensitivity of the adenosine 5'-triphosphate-dependent K+ channel in mouse pancreatic beta-cells.
British journal of pharmacology 1992;107(1):87-94.
1992: Mathias Schwanstecher; S Behrends; C Brandt; Uwe Panten
The binding properties of the solubilized sulfonylurea receptor from a pancreatic B-cell line are modulated by the Mg(++)-complex of ATP.
The Journal of pharmacology and experimental therapeutics 1992;262(2):495-502.
1992: Mathias Schwanstecher; C Brandt; S Behrends; U Schaupp; Uwe Panten
Effect of MgATP on pinacidil-induced displacement of glibenclamide from the sulphonylurea receptor in a pancreatic beta-cell line and rat cerebral cortex.
British journal of pharmacology 1992;106(2):295-301.
1992: Mathias Schwanstecher; S Löser; C Brandt; K Scheffer; F Rosenberger; Uwe Panten
Adenine nucleotide-induced inhibition of binding of sulphonylureas to their receptor in pancreatic islets.
British journal of pharmacology 1992;105(3):531-4.
1992: Christina Schwanstecher; C Dickel; Uwe Panten
Cytosolic nucleotides enhance the tolbutamide sensitivity of the ATP-dependent K+ channel in mouse pancreatic B cells by their combined actions at inhibitory and stimulatory receptors.
Molecular pharmacology 1992;41(3):480-6.
1991: Mathias Schwanstecher; S Löser; I Rietze; Uwe Panten
Phosphate and thiophosphate group donating adenine and guanine nucleotides inhibit glibenclamide binding to membranes from pancreatic islets.
Naunyn-Schmiedeberg's archives of pharmacology 1991;343(1):83-9.
1990: Uwe Panten; C Heipel; F Rosenberger; K Scheffer; B J Zünkler; Christina Schwanstecher
Tolbutamide-sensitivity of the adenosine 5'-triphosphate-dependent K+ channel in mouse pancreatic B-cells.
Naunyn-Schmiedeberg's archives of pharmacology 1990;342(5):566-74.
1990: Sigurd Lenzen; S Freytag; Uwe Panten; P R Flatt; C J Bailey
Alloxan and ninhydrin inhibition of hexokinase from pancreatic islets and tumoural insulin-secreting cells.
Pharmacology & toxicology 1990;66(3):157-62.
1989: B J Zünkler; G Trube; Uwe Panten
How do sulfonylureas approach their receptor in the B-cell plasma membrane?
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(3):328-32.
1989: Uwe Panten; J Burgfeld; F Goerke; M Rennicke; Mathias Schwanstecher; A Wallasch; B J Zünkler; Sigurd Lenzen
Control of insulin secretion by sulfonylureas, meglitinide and diazoxide in relation to their binding to the sulfonylurea receptor in pancreatic islets.
Biochemical pharmacology 1989;38(8):1217-29.
1989: Uwe Panten
Mechanism of insulin secretion and its modulation by sulfonylureas.
Contributions to nephrology 1989;73():16-21; discussion 22-3.
1988: B J Zünkler; S Lins; T Ohno-Shosaku; G Trube; Uwe Panten
Cytosolic ADP enhances the sensitivity to tolbutamide of ATP-dependent K+ channels from pancreatic B-cells.
FEBS letters 1988;239(2):241-4.
1988: Sigurd Lenzen; F H Brand; Uwe Panten
Structural requirements of alloxan and ninhydrin for glucokinase inhibition and of glucose for protection against inhibition.
British journal of pharmacology 1988;95(3):851-9.
1988: Uwe Panten; Mathias Schwanstecher; A Wallasch; Sigurd Lenzen
Glucose both inhibits and stimulates insulin secretion from isolated pancreatic islets exposed to maximally effective concentrations of sulfonylureas.
Naunyn-Schmiedeberg's archives of pharmacology 1988;338(4):459-62.
1988: Sigurd Lenzen; S Freytag; Uwe Panten
Inhibition of glucokinase by alloxan through interaction with SH groups in the sugar-binding site of the enzyme.
Molecular pharmacology 1988;34(3):395-400.
1988: Sigurd Lenzen; Uwe Panten
Alloxan: history and mechanism of action.
Diabetologia 1988;31(6):337-42.
1988: Sigurd Lenzen; Uwe Panten
Signal recognition by pancreatic B-cells.
Biochemical pharmacology 1988;37(3):371-8.
1988: B J Zünkler; Sigurd Lenzen; K Männer; Uwe Panten; G Trube
Concentration-dependent effects of tolbutamide, meglitinide, glipizide, glibenclamide and diazoxide on ATP-regulated K+ currents in pancreatic B-cells.
Naunyn-Schmiedeberg's archives of pharmacology 1988;337(2):225-30.
1986: Uwe Panten; B J Zünkler; S Scheit; K Kirchhoff; Sigurd Lenzen
Regulation of energy metabolism in pancreatic islets by glucose and tolbutamide.
Diabetologia 1986;29(9):648-54.
1985: S Zielmann; G Schütte; Sigurd Lenzen; Uwe Panten
Effects of isoprenaline and glucagon on insulin secretion from pancreatic islets.
Naunyn-Schmiedeberg's archives of pharmacology 1985;329(3):299-304.
1985: Uwe Panten; S Zielmann; M T Schrader; Sigurd Lenzen
The dihydropyridine derivative, Bay K 8644, enhances insulin secretion by isolated pancreatic islets.
Naunyn-Schmiedeberg's archives of pharmacology 1985;328(3):351-3.
1984: Uwe Panten; S Zielmann; J Langer; B J Zünkler; Sigurd Lenzen
Regulation of insulin secretion by energy metabolism in pancreatic B-cell mitochondria. Studies with a non-metabolizable leucine analogue.
The Biochemical journal 1984;219(1):189-96.
1983: J Langer; Uwe Panten; S Zielmann
Effects of alpha-adrenoceptor antagonists on clonidine-induced inhibition of insulin secretion by isolated pancreatic islets.
British journal of pharmacology 1983;79(2):415-20.
1981: Uwe Panten; J Langer
Mechanism of 3-phenylpyruvate-induced insulin release from isolated pancreatic islets.
The Biochemical journal 1981;198(2):353-6.