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Moreno Paolini

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Simone Melega; Eleonora Pagnotta; Donatella Canistro; Renato Iori; Andrea Sapone; Moreno Paolini
Effect of sprout extract from Tuscan black cabbage on xenobiotic-metabolizing and antioxidant enzymes in rat liver.
Donatella Canistro; Renato Iori; Simone Melega; Andrea Sapone; Ester Speroni; Jessica Barillari; Moreno Paolini
Black cabbage seed extract affects rat Cyp-mediated biotransformation: organ and sex related differences.
Andrea Sapone; Fabio Vivarelli; Donatella Canistro; Simone Melega; Ramona Moles; Moreno Paolini
On enzyme-based anticancer molecular dietary manipulations.

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All Publications

2013: Simone Melega; Eleonora Pagnotta; Donatella Canistro; Renato Iori; Andrea Sapone; Moreno Paolini
Effect of sprout extract from Tuscan black cabbage on xenobiotic-metabolizing and antioxidant enzymes in rat liver.
Mutation research 2013;751(1):45-51.
2012: Donatella Canistro; Renato Iori; Simone Melega; Andrea Sapone; Ester Speroni; Jessica Barillari; Moreno Paolini
Black cabbage seed extract affects rat Cyp-mediated biotransformation: organ and sex related differences.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(8):2612-21.
2012: Andrea Sapone; Fabio Vivarelli; Donatella Canistro; Simone Melega; Ramona Moles; Moreno Paolini
On enzyme-based anticancer molecular dietary manipulations.
Journal of biomedicine & biotechnology 2012;2012():790987.
2011: Jukka Puoliväli; Raimo Pussinen; Francesca Riccardino; Andrea Sapone; Antonio Soleti; Enzo Spisni; Leena Tähtivaara; Nina Vartiainen; Juha Yrjänheikki; Donatella Canistro; Taneli Heikkinen; Giedrius Kalesnykas; Kimmo Lehtimäki; Taina-Kaisa Miettinen; Antti Nurmi; Moreno Paolini
The radical scavenger IAC (bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl) decantionate) decreases mortality, enhances cognitive functions in water maze and reduces amyloid plaque burden in hAβPP transgenic mice.
Journal of Alzheimer's disease : JAD 2011;27(3):499-510.
2010: Valentina Vasina; Massimiliano Broccoli; Maria Grazia Ursino; Donatella Canistro; Luca Valgimigli; Antonio Soleti; Moreno Paolini; Fabrizio De Ponti
Non-peptidyl low molecular weight radical scavenger IAC attenuates DSS-induced colitis in rats.
World journal of gastroenterology : WJG 2010;16(29):3642-50.
2010: Michela Novelli; Barbara Bonamassa; Matilde Masini; Nicola Funel; Donatella Canistro; Vincenzo De Tata; M Martano; A Soleti; Daniela Campani; Moreno Paolini; Pellegrino Masiello
Persistent correction of hyperglycemia in streptozotocin-nicotinamide-induced diabetic mice by a non-conventional radical scavenger.
Naunyn-Schmiedeberg's archives of pharmacology 2010;382(2):127-37.
2010: Donatella Canistro; Alessandra A Affatato; Antonio Soleti; Vincenzo Mollace; Carolina Muscoli; Francesca Sculco; Iolanda Sacco; Valeria Visalli; Barbara Bonamassa; Manuela Martano; Michelangelo Iannone; Andrea Sapone; Moreno Paolini
The novel radical scavenger IAC is effective in preventing and protecting against post-ischemic brain damage in Mongolian gerbils.
Journal of the neurological sciences 2010;290(1-2):90-5.
2009: Valentina D'Aleo; SILVIA DEL GUERRA; Manuela Martano; Barbara Bonamassa; Donatella Canistro; Antonio Soleti; Luca Valgimigli; Moreno Paolini; Franco Filipponi; Ugo Boggi; Stefano Del Prato; ROBERTO LUPI
The non-peptidyl low molecular weight radical scavenger IAC protects human pancreatic islets from lipotoxicity.
Molecular and cellular endocrinology 2009;309(1-2):63-6.
2009: Valentina Vasina; Massimiliano Broccoli; Maria Grazia Ursino; Simona Fiò Bellot; Antonio Soleti; Moreno Paolini; Fabrizio De Ponti
Effects of the non-peptidyl low molecular weight radical scavenger IAC in DNBS-induced colitis in rats.
European journal of pharmacology 2009;614(1-3):137-45.
2009: Cristophe Crochemore; Marco Virgili; Barbara Bonamassa; Donatella Canistro; Luis Emiliano Peña-Altamira; Moreno Paolini; Antonio Contestabile
Long-term dietary administration of valproic acid does not affect, while retinoic acid decreases, the lifespan of G93A mice, a model for amyotrophic lateral sclerosis.
Muscle & nerve 2009;39(4):548-52.
2009: Donatella Canistro; Barbara Bonamassa; Laura Pozzetti; Andrea Sapone; S Z Abdel-Rahman; Gian Luigi Biagi; Moreno Paolini
Alteration of xenobiotic metabolizing enzymes by resveratrol in liver and lung of CD1 mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2009;47(2):454-61.
2009: A Sapone; Donatella Canistro; Barbara Bonamassa; Gian Luigi Biagi; Moreno Paolini
Hidden paradoxes in generic drug substitution affecting pharmacotherapy.
Journal of biomedicine & biotechnology 2009;2009():801984.
2008: Antti Nurmi; Taina-Kaisa Miettinen; Jukka Puoliväli; Raimo Pussinen; Antonio Soleti; Karim Bagate; Francesca Riccardino; Robert Grundy; Juha Yrjänheikki; Donatella Canistro; Moreno Paolini
Neuroprotective properties of the non-peptidyl radical scavenger IAC in rats following transient focal cerebral ischemia.
Brain research 2008;1207():174-81.
2008: Alessio Papi; M Orlandi; G Bartolini; Jessica Barillari; Renato Iori; Moreno Paolini; Fiammetta Ferroni; Maria Grazia Fumo; Gian Franco Pedulli; Luca Valgimigli
Cytotoxic and antioxidant activity of 4-methylthio-3-butenyl isothiocyanate from Raphanus sativus L. (Kaiware Daikon) sprouts.
Journal of agricultural and food chemistry 2008;56(3):875-83.
2008: Rita Mancarella; SILVIA DEL GUERRA; Matilde Masini; Marco Bugliani; Luca Valgimigli; Gian Franco Pedulli; Moreno Paolini; Donatella Canistro; Andrea Armando; Antonio Soleti; Franco Filipponi; Franco Mosca; Ugo Boggi; Stefano Del Prato; Piero Marchetti; ROBERTO LUPI
Beneficial effect of the nonpeptidyl low molecular weight radical scavenger IAC on cultured human islet function.
Cell transplantation 2008;17(10-11):1271-6.
2008: Donatella Canistro; Laura Pozzetti; Andrea Sapone; Massimiliano Broccoli; Alessandra Affatato; A Stradiotti; V Longo; Paola Menichini; R Barale; Moreno Paolini
Perturbation of murine liver cyp-superfamily of isoforms by different combinations of pesticide mixtures.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(1):34-42.
2008: Donatella Canistro; Laura Pozzetti; Andrea Sapone; Massimiliano Broccoli; Barbara Bonamassa; V Longo; V Lubrano; Jessica Barillari; Gian Luigi Biagi; Moreno Paolini
Perturbation of rat hepatic metabolising enzymes by folic acid supplementation.
Mutation research 2008;637(1-2):16-22.
2007: Michela Novelli; Valentina D'Aleo; ROBERTO LUPI; Moreno Paolini; Antonio Soleti; Piero Marchetti; Pellegrino Masiello
Reduction of oxidative stress by a new low-molecular-weight antioxidant improves metabolic alterations in a nonobese mouse diabetes model.
Pancreas 2007;35(4):e10-7.
2007: Kevin J Wolfe; Jeffrey K Wickliffe; Courtney E Hill; Moreno Paolini; Marinel M Ammenheuser; Sherif Z Abdel-Rahman
Single nucleotide polymorphisms of the DNA repair gene XPD/ERCC2 alter mRNA expression.
Pharmacogenetics and genomics 2007;17(11):897-905.
2007: ROBERTO LUPI; SILVIA DEL GUERRA; R Mancarella; M Novelli; Luca Valgimigli; G F Pedulli; Moreno Paolini; A Soleti; F Filipponi; F Mosca; U Boggi; Stefano Del Prato; Pellegrino Masiello; P Marchetti
Insulin secretion defects of human type 2 diabetic islets are corrected in vitro by a new reactive oxygen species scavenger.
Diabetes & metabolism 2007;33(5):340-5.
2007: Andrea Sapone; Barbara Bonamassa; Donatella Canistro; Laura Pozzetti; Moreno Paolini
High-dose vitamin A.
Lancet 2007;370(9589):740.
2007: Jessica Barillari; Renato Iori; Massimiliano Broccoli; Laura Pozzetti; Donatella Canistro; Andrea Sapone; Barbara Bonamassa; Gian Luigi Biagi; Moreno Paolini
Glucoraphasatin and glucoraphenin, a redox pair of glucosinolates of brassicaceae, differently affect metabolizing enzymes in rats.
Journal of agricultural and food chemistry 2007;55(14):5505-11.
2007: Andrea Sapone; Alessandra Affatato; Donatella Canistro; Laura Pozzetti; Massimiliano Broccoli; Jessica Barillari; Renato Iori; Moreno Paolini
Cruciferous vegetables and lung cancer.
Mutation research 2007;635(2-3):146-8.
2007: Andrea Sapone; Bianca Gustavino; Monica Monfrinotti; Donatella Canistro; Massimiliano Broccoli; Laura Pozzetti; Alessandra Affatato; Luca Valgimigli; Giorgio Cantelli Forti; Gian Franco Pedulli; Gian Luigi Biagi; Sherif Z Abdel-Rahman; Moreno Paolini
Perturbation of cytochrome P450, generation of oxidative stress and induction of DNA damage in Cyprinus carpio exposed in situ to potable surface water.
Mutation research 2007;626(1-2):143-54.
2006: Paolo Perocco; Gabriele Bronzetti; Donatella Canistro; Luca Valgimigli; Andrea Sapone; Alessandra Affatato; Gian Franco Pedulli; Laura Pozzetti; Massimiliano Broccoli; Renato Iori; Jessica Barillari; Valeriana Sblendorio; Marvin S Legator; Moreno Paolini; Sherif Z Abdel-Rahman
Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver.
Mutation research 2006;595(1-2):125-36.
2005: Jessica Barillari; Rinaldo Cervellati; Moreno Paolini; Arnaud Tatibouët; Patrick Rollin; Renato Iori
Isolation of 4-methylthio-3-butenyl glucosinolate from Raphanus sativus sprouts (kaiware daikon) and its redox properties.
Journal of agricultural and food chemistry 2005;53(26):9890-6.
2005: Andrea Sapone; Donatella Canistro; Massimiliano Broccoli; Laura Pozzetti; Alessandra Affatato; Stefano Vangelisti; Gian Luigi Biagi; Valeriana Sblendorio; Moreno Paolini
Green tea and its isolated constituents in cancer prevention.
Mutation research 2005;578(1-2):434-5.
2005: Paolo Toti; Antonella Petri; Valerio Pelaia; Ahmed M Osman; Moreno Paolini; Carlo Bauer
A linearization method for low catalytic activity enzyme kinetic analysis.
Biophysical chemistry 2005;114(2-3):245-51.
2005: Jessica Barillari; Donatella Canistro; Moreno Paolini; Fiammetta Ferroni; Gian Franco Pedulli; Renato Iori; Luca Valgimigli
Direct antioxidant activity of purified glucoerucin, the dietary secondary metabolite contained in rocket (Eruca sativa Mill.) seeds and sprouts.
Journal of agricultural and food chemistry 2005;53(7):2475-82.
2005: Andrea Sapone; Laura Pozzetti; Donatella Canistro; Massimiliano Broccoli; Gabriele Bronzetti; Giuseppa Potenza; Alessandra Affatato; Gian Luigi Biagi; Giorgio Cantelli-Forti; Moreno Paolini
CYP superfamily perturbation by diflubenzuron or acephate in different tissues of CD1 mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2005;43(1):173-83.
2004: Marco Valgimigli; Elisa Merli; Patrizia Malagutti; Olga Soukhomovskaia; Giordano Cicchitelli; Alessandra Antelli; Donatella Canistro; Gloria Francolini; Gaetano Macrì; Francesca Mastrorilli; Moreno Paolini; Roberto Ferrari
Hydroxyl radical generation, levels of tumor necrosis factor-alpha, and progression to heart failure after acute myocardial infarction.
Journal of the American College of Cardiology 2004;43(11):2000-8.
2004: Moreno Paolini; Andrea Sapone; Frank J Gonzalez
Parkinson's disease, pesticides and individual vulnerability.
Trends in pharmacological sciences 2004;25(3):124-9.
2004: Donatella Canistro; C Della Croce; Renato Iori; Jessica Barillari; Gabriele Bronzetti; G Poi; Marco Cini; Leonardo Caltavuturo; Paolo Perocco; Moreno Paolini
Genetic and metabolic effects of gluconasturtiin, a glucosinolate derived from cruciferae.
Mutation research 2004;545(1-2):23-35.
2004: Moreno Paolini; Paolo Perocco; Donatella Canistro; Luca Valgimigli; Gian Franco Pedulli; Renato Iori; Clara Della Croce; Giorgio Cantelli-Forti; Marvin S Legator; Sherif Z Abdel-Rahman
Induction of cytochrome P450, generation of oxidative stress and in vitro cell-transforming and DNA-damaging activities by glucoraphanin, the bioprecursor of the chemopreventive agent sulforaphane found in broccoli.
Carcinogenesis 2004;25(1):61-7.
2003: Moreno Paolini; Andrea Sapone; Donatella Canistro; Pasquale Chieco; Luca Valgimigli
Antioxidant vitamins for prevention of cardiovascular disease.
Lancet 2003;362(9387):920; author reply 921.
2003: Moreno Paolini; Andrea Sapone; Luca Valgimigli
Avoidance of bioflavonoid supplements during pregnancy: a pathway to infant leukemia?
Mutation research 2003;527(1-2):99-101.
2003: Andrea Sapone; Alessandra Affatato; Donatella Canistro; Massimiliano Broccoli; Silvia Trespidi; Laura Pozzetti; Gian Luigi Biagi; Giorgio Cantelli-Forti; Moreno Paolini
Induction and suppression of cytochrome P450 isoenzymes and generation of oxygen radicals by procymidone in liver, kidney and lung of CD1 mice.
Mutation research 2003;527(1-2):67-80.
2003: Moreno Paolini; Sherif Z Abdel-Rahman; Andrea Sapone; Gian Franco Pedulli; Paolo Perocco; Giorgio Cantelli-Forti; Marvin S Legator
Beta-carotene: a cancer chemopreventive agent or a co-carcinogen?
Mutation research 2003;543(3):195-200.
2003: Moreno Paolini; Marion Nestle
Pitfalls of enzyme-based molecular anticancer dietary manipulations: food for thought.
Mutation research 2003;543(3):181-9.
2003: Andrea Sapone; Dino Vaira; Silvia Trespidi; Federico Perna; Luigi Gatta; Andrea Tampieri; Chiara Ricci; Giorgio Cantelli-Forti; Mario Miglioli; Gian Luigi Biagi; Moreno Paolini
The clinical role of cytochrome p450 genotypes in Helicobacter pylori management.
The American journal of gastroenterology 2003;98(5):1010-5.
2003: Moreno Paolini; Luca Valgimigli; Emanuela Marchesi; Silvia Trespidi; Gian Franco Pedulli
Taking EPR "snapshots" of the oxidative stress status in human blood.
Free radical research 2003;37(5):503-8.
2003: Moreno Paolini; Andrea Sapone; Donatella Canistro; Maria Antonietta Antonelli; Pasquale Chieco
Diet and risk of cancer.
Lancet 2003;361(9353):257-8.
2002: Moreno Paolini; Andrea Sapone; Donatella Canistro; Pasquale Chieco; Carlo Bauer
Dietary effect on blood pressure.
Lancet 2002;360(9347):1786.
2002: Donatella Canistro; Giorgio Cantelli-Forti; Gian Luigi Biagi; Moreno Paolini
Re: dioxin increases reactive oxygen production in mouse liver mitochondria (toxicol. Appl. Pharmacol.178, 15-21, 2002). To the editor.
Toxicology and applied pharmacology 2002;185(1):74-5.
2002: Paolo Perocco; Renato Iori; Jessica Barillari; Massimiliano Broccoli; Andrea Sapone; Alessandra Affatato; Moreno Paolini
In vitro induction of benzo(a)pyrene cell-transforming activity by the glucosinolate gluconasturtiin found in cruciferous vegetables.
Cancer letters 2002;184(1):65-71.
2002: Moreno Paolini; Laura Pozzetti; Marco Montagnani; Giuseppa Potenza; Laura Sabatini; Alessandra Antelli; Giorgio Cantelli-Forti; Aldo Roda
Ursodeoxycholic acid (UDCA) prevents DCA effects on male mouse liver via up-regulation of CYP [correction of CXP] and preservation of BSEP activities.
Hepatology (Baltimore, Md.) 2002;36(2):305-14.
2002: Andrea Sapone; Moreno Paolini; Gian Luigi Biagi; Giorgio Cantelli-Forti; Frank J Gonzalez
The pressing need for combined genotype-phenotype analysis in clinical practice.
Trends in pharmacological sciences 2002;23(6):260-1.
2002: Maria Clelia Guerra; Cecilia Renzulli; Alessandra Antelli; Laura Pozzetti; Moreno Paolini; Ester Speroni
Effects of trivalent chromium on hepatic CYP-linked monooxygenases in laying hens.
Journal of applied toxicology : JAT 2002;22(3):161-5.
2001: Luca Valgimigli; Gian Franco Pedulli; Moreno Paolini
Measurement of oxidative stress by EPR radical-probe technique.
Free radical biology & medicine 2001;31(6):708-16.
2001: Moreno Paolini; Alessandra Antelli; Laura Pozzetti; D Spetlova; Paolo Perocco; Luca Valgimigli; Gian Franco Pedulli; Giorgio Cantelli-Forti
Induction of cytochrome P450 enzymes and over-generation of oxygen radicals in beta-carotene supplemented rats.
Carcinogenesis 2001;22(9):1483-95.
2001: Moreno Paolini; Sherif Z Abdel-Rahman; Giorgio Cantelli-Forti; Marvin S Legator
Chemoprevention or antichemoprevention? A salutary warning From the beta-carotene experience.
Journal of the National Cancer Institute 2001;93(14):1110-1.
2001: Moreno Paolini; G L Biagi; G Cantelli-Forti; C Bauer
Plasma ascorbic acid in heart disease.
Lancet 2001;358(9275):71-2.
2001: Moreno Paolini; Giuseppa Potenza; Gian Luigi Biagi; Giorgio Cantelli-Forti
Re: ethylbenzene induces microsomal oxygen free radical generation: antibody-directed characterization of the responsible cytochrome p450 enzymes (toxicol. appl. pharmacol. 164, 305-311, 2000).
Toxicology and applied pharmacology 2001;173(3):188-9.
2001: Carlo Bauer; Ahmed M Osman; G Cercignani; N Gialluca; Moreno Paolini
A unified theory of enzyme kinetics based upon the systematic analysis of the variations of k(cat), K(M), and k(cat)/K(M) and the relevant DeltaG(0 not equal) values-possible implications in chemotherapy and biotechnology.
Biochemical pharmacology 2001;61(9):1049-55.
2001: Moreno Paolini; G L Biagi; Giorgio Cantelli-Forti
Cyclosporin A and free radical generation.
Trends in pharmacological sciences 2001;22(1):14-6.
2000: Maria Clelia Guerra; Ester Speroni; Massimiliano Broccoli; M Cangini; Patrizia Pasini; A Minghett; N Crespi-Perellino; Mara Mirasoli; Giorgio Cantelli-Forti; Moreno Paolini
Comparison between chinese medical herb Pueraria lobata crude extract and its main isoflavone puerarin antioxidant properties and effects on rat liver CYP-catalysed drug metabolism.
Life sciences 2000;67(24):2997-3006.
2000: Paolo Perocco; M Mazzullo; Massimiliano Broccoli; Paola Rocchi; Anna Maria Ferreri; Moreno Paolini
Inhibitory activity of vitamin E and alpha-naphthoflavone on beta-carotene-enhanced transformation of BALB/c 3T3 cells by benzo(a)pyrene and cigarette-smoke condensate.
Mutation research 2000;465(1-2):151-8.
2000: Moreno Paolini; Laura Pozzetti; F Piazza; Maria Clelia Guerra; Ester Speroni; Giorgio Cantelli-Forti; Aldo Roda
Mechanism for the prevention of cholestasis involving cytochrome P4503A overexpression.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2000;48(1):49-59.
1999: Moreno Paolini; Jessica Barillari; Silvia Trespidi; Luca Valgimigli; Gian Franco Pedulli; Giorgio Cantelli-Forti
Captan impairs CYP-catalyzed drug metabolism in the mouse.
Chemico-biological interactions 1999;123(2):149-70.
1999: Moreno Paolini; Jessica Barillari; Massimiliano Broccoli; Laura Pozzetti; Paolo Perocco; Giorgio Cantelli-Forti
Effect of liquorice and glycyrrhizin on rat liver carcinogen metabolizing enzymes.
Cancer letters 1999;145(1-2):35-42.
1999: Moreno Paolini; Laura Pozzetti; F Piazza; Giorgio Cantelli-Forti; Aldo Roda
Bile acid structure and selective modulation of murine hepatic cytochrome P450-linked enzymes.
Hepatology (Baltimore, Md.) 1999;30(3):730-9.
1999: Laura Pozzetti; Moreno Paolini; Jessica Barillari; Giorgio Cantelli-Forti
Induction and suppression of murine CYP-mediated biotransformation by dithianon: organ- and sex-related differences.
Cancer letters 1999;141(1-2):47-56.
1999: Moreno Paolini; Giorgio Cantelli-Forti; Paolo Perocco; Gian Franco Pedulli; Sherif Z Abdel-Rahman; Marvin S Legator
Co-carcinogenic effect of beta-carotene.
Nature 1999;398(6730):760-1.
1999: Paolo Perocco; Moreno Paolini; M Mazzullo; Gian Luigi Biagi; Giorgio Cantelli-Forti
beta-carotene as enhancer of cell transforming activity of powerful carcinogens and cigarette-smoke condensate on BALB/c 3T3 cells in vitro.
Mutation research 1999;440(1):83-90.
1999: Moreno Paolini; Laura Pozzetti; Paolo Perocco; M Mazzullo; Giorgio Cantelli-Forti
Molecular non-genetic biomarkers of effect related to methyl thiophanate cocarcinogenesis: organ- and sex-specific cytochrome P450 induction in the rat.
Cancer letters 1999;135(2):203-13.
1999: Moreno Paolini; G L Biagi; G Cantelli-Forti
Glutathione transferase polymorphism and Parkinson's disease.
Lancet 1999;353(9146):71-2.
1999: Moreno Paolini; Gian Luigi Biagi; Giorgio Cantelli-Forti
The many consequences of chemical- and genetic-based modulation of drug metabolizing enzyme activities.
Life sciences 1999;65(8):PL75-9.
1999: Moreno Paolini; Laura Pozzetti; Gian Franco Pedulli; Emanuela Marchesi; Giorgio Cantelli-Forti
The nature of prooxidant activity of vitamin C.
Life sciences 1999;64(23):PL 273-8.
1998: Moreno Paolini
Brussels sprouts: an exceptionally rich source of ambiguity for anticancer strategies.
Toxicology and applied pharmacology 1998;152(2):293-4.
1998: Giorgio Cantelli-Forti; Patrizia Hrelia; Moreno Paolini
The pitfall of detoxifying enzymes.
Mutation research 1998;402(1-2):179-83.
1998: Moreno Paolini; Laura Pozzetti; P Silingardi; Clara Della Croce; Gabriele Bronzetti; Giorgio Cantelli-Forti
Isolation of a novel metabolizing system enriched in phase-II enzymes for short-term genotoxicity bioassays.
Mutation research 1998;413(3):205-17.
1998: Moreno Paolini; Gian Luigi Biagi; C Bauer; Giorgio Cantelli-Forti
Enzyme evolution and cancer: hypothesis why natural carcinogens are more potent than synthetic ones.
Life sciences 1998;63(24):2141-6.
1998: Moreno Paolini; R Mesirca; Laura Pozzetti; N Gialluca; C Bauer; Gian Luigi Biagi; Giorgio Cantelli-Forti
Cancer chemoprevention: some complications and limitations.
Cancer detection and prevention 1998;22(1):68-74.
1998: Moreno Paolini; Laura Pozzetti; Andrea Sapone; Giorgio Cantelli-Forti
Effect of licorice and glycyrrhizin on murine liver CYP-dependent monooxygenases.
Life sciences 1998;62(6):571-82.
1997: Moreno Paolini; Gian Luigi Biagi; Giorgio Cantelli-Forti
Cancer chemoprevention from the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazol[4,5-b]pyridine: reconsideration of the evidence.
Mutation research 1997;381(2):279-82.
1997: Paolo Perocco; C Del Ciello; M Mazzullo; Paola Rocchi; Anna Maria Ferreri; Moreno Paolini; Laura Pozzetti; Giorgio Cantelli-Forti
Cytotoxic and cell transforming activities of the fungicide methyl thiophanate on BALB/c 3T3 cells in vitro.
Mutation research 1997;394(1-3):29-35.
1997: Moreno Paolini; Laura Pozzetti; Andrea Sapone; Gian Luigi Biagi; Giorgio Cantelli-Forti
Development of basal and induced testosterone hydroxylase activity in the chicken embryo in ovo.
British journal of pharmacology 1997;122(2):344-50.
1997: Moreno Paolini; Giorgio Cantelli-Forti
On the metabolizing systems for short-term genotoxicity assays: a review.
Mutation research 1997;387(1):17-34.
1997: Moreno Paolini; Laura Pozzetti; Andrea Sapone; R Mesirca; Paolo Perocco; M Mazzullo; Giorgio Cantelli-Forti
Molecular non-genetic biomarkers of effect related to acephate cocarcinogenesis: sex- and tissue-dependent induction or suppression of murine CYPs.
Cancer letters 1997;117(1):7-15.
1997: Moreno Paolini; G L Biagi; Giorgio Cantelli-Forti
The metalloporphyrin/oxidant model for cytochrome P450.
Mutation research 1997;377(2):287, 289.
1997: Moreno Paolini; G L Biagi; Giorgio Cantelli-Forti
Re: Barcelo, S., Gardiner, J.M., and Gescher, A. and Chipman, J.K. (1996) CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane. Carcinogenesis, 17, 277-282.
Carcinogenesis 1997;18(7):1435-6.
1997: Moreno Paolini; G L Biagi; Giorgio Cantelli-Forti
A hidden paradox in carcinogenesis bioassays.
Journal of the National Cancer Institute 1997;89(10):736-7.
1997: Moreno Paolini; R Mesirca; Laura Pozzetti; Andrea Sapone; Giorgio Cantelli-Forti
Biomarkers of effect in evaluating dithianon cocarcinogenesis: selective induction and suppression of murine CYP3A isoform.
Cancer letters 1997;113(1-2):221-8.
1997: M Mazzullo; R Mesirca; Moreno Paolini; Giorgio Cantelli-Forti; Paolo Perocco; P Ciaccia; Stefano Grilli
A database for evaluating the toxicological risk of pesticides.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 1997;16(2-3):231-7.
1997: Moreno Paolini; G L Biagi; Giorgio Cantelli-Forti
Commentary--measurement of microsomal epoxide hydrolase activity in humans: problems and perspectives.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 1997;16(2-3):73-6.
1996: Moreno Paolini; R Mesirca; Laura Pozzetti; Andrea Sapone; Giorgio Cantelli-Forti
Biomarkers of effect in evaluating metalaxyl cocarcinogenesis. Selective induction of murine CYP 3A isoform.
Mutation research 1996;361(2-3):157-64.
1996: Moreno Paolini; Laura Pozzetti; Gian Franco Pedulli; M Cipollone; R Mesirca; Giorgio Cantelli-Forti
Paramagnetic resonance in detecting carcinogenic risk from cytochrome P450 overexpression.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 1996;44(8):470-3.
1996: Paolo Perocco; C Del Ciello; A Colacci; Laura Pozzetti; Moreno Paolini; Giorgio Cantelli-Forti; S Grilli
Cytotoxic activity and transformation of BALB/c 3T3 cells in vitro by the insecticide acephate.
Cancer letters 1996;106(2):147-53.
1996: Patrizia Hrelia; Carmela Fimognari; Francesca Maffei; F Vigagni; R Mesirca; Laura Pozzetti; Moreno Paolini; Giorgio Cantelli-Forti
The genetic and non-genetic toxicity of the fungicide Vinclozolin.
Mutagenesis 1996;11(5):445-53.
1996: Moreno Paolini; R Mesirca; Laura Pozzetti; Francesca Maffei; F Vigagni; Patrizia Hrelia; Giorgio Cantelli-Forti
Genetic and non-genetic biomarkers related to carcinogenesis in evaluating toxicological risk from Fenarimol.
Mutation research 1996;368(1):27-39.
1996: Moreno Paolini; R Mesirca; Laura Pozzetti; Andrea Sapone; Giorgio Cantelli-Forti
Molecular non-genetic biomarkers related to Fenarimol cocarcinogenesis: organ- and sex-specific CYP induction in rat.
Cancer letters 1996;101(2):171-8.
1996: Moreno Paolini; Laura Pozzetti; R Mesirca; Andrea Sapone; Giorgio Cantelli-Forti
Testosterone hydroxylase in evaluating induction and suppression of murine CYP isoenzymes by fenarimol.
Archives of toxicology 1996;70(7):451-6.
1995: Moreno Paolini; R Mesirca; N Gialluca; C Bauer; Gian Luigi Biagi; Giorgio Cantelli-Forti
On cancer chemoprevention: complications and limitations of some proposed strategies.
Carcinogenesis 1995;16(4):971-3.
1995: Moreno Paolini; R Mesirca; Laura Pozzetti; Andrea Sapone; Giorgio Cantelli-Forti
Induction of CYP2B1 mediated pentoxyresorufin O-dealkylase activity in different species, sex and tissue by prototype 2B1-inducers.
Chemico-biological interactions 1995;95(1-2):127-39.
1994: Patrizia Hrelia; M Morotti; F Vigagni; Francesca Maffei; Moreno Paolini; R Mesirca; Giorgio Cantelli-Forti
The modulating activity of interferon on benzo(a)pyrene bioactivation and clastogenesis in mice.
Pharmacology & toxicology 1994;74(4-5):249-54.
1994: Moreno Paolini; Gian Luigi Biagi; C Bauer; Giorgio Cantelli-Forti
On the procedures for isolation of S9 fractions from induced rodents in in vitro genotoxicity assays.
Teratogenesis, carcinogenesis, and mutagenesis 1994;14(2):101-3.
1993: Giorgio Cantelli-Forti; Moreno Paolini; Patrizia Hrelia
Multiple end point procedure to evaluate risk from pesticides.
Environmental health perspectives 1993;101 Suppl 3():15-20.
1993: Patrizia Hrelia; M Morotti; F Vigagni; Francesca Maffei; Moreno Paolini; G C Forti
Murine alpha/beta interferons inhibit benzo(a)pyrene activation and mutagenesis in mice.
Basic life sciences 1993;61():325-34.
1992: Moreno Paolini; R Mesirca; Laura Pozzetti; P Silingardi; S Grilli; Giorgio Cantelli-Forti
Strategies for advancement of short-term mutagenicity tests: on the optimal ionic strength for the liver microsomal assay.
Carcinogenesis 1992;13(8):1403-8.
1992: E Sapigni; Moreno Paolini; R Mesirca; Patrizia Hrelia; P Roncada; Giorgio Cantelli-Forti
Short-chain aliphatic halocompounds: "in vivo" effects on microsomal monooxygenase (P450-dependent) system.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;25 Suppl 1():77-8.
1992: Moreno Paolini; E Sapigni; R Mesirca; Gian Franco Pedulli; FP Corongiu; M Assunta Dessi; Giorgio Cantelli-Forti
On the hepatotoxicity of 1,1,2,2-tetrachloroethane.
Toxicology 1992;73(1):101-15.
1991: Moreno Paolini; Gian Luigi Biagi; C Bauer; Giorgio Cantelli-Forti
Is clonal adaptation a product of evolution over the millennia?
Biochemical pharmacology 1991;42(3):457-8.
1991: Moreno Paolini; E Sapigni; Patrizia Hrelia; M Scotti; M Morotti; Giorgio Cantelli-Forti
Wide spectrum detection of precarcinogens in short-term bioassays by simultaneous superinduction of multiple forms of cytochrome P450 isoenzymes.
Carcinogenesis 1991;12(5):759-66.
1991: William W Au; W Anwar; Moreno Paolini; S Ramanujam; Giorgio Cantelli-Forti
Mechanism of clastogenic and co-clastogenic activity of cremophore with benzene in mice.
Carcinogenesis 1991;12(1):53-7.
1990: Patrizia Hrelia; M Morotti; M Scotti; F Vigagni; Moreno Paolini; Paolo Perocco; Giorgio Cantelli-Forti
Genotoxic risk associated with pesticides: evidences on short-term tests.
Pharmacological research : the official journal of the Italian Pharmacological Society 1990;22 Suppl 3():93-4.
1990: Moreno Paolini; E Sapigni; Patrizia Hrelia; S Grilli; G Lattanzi; M Scotti; Giorgio Cantelli-Forti
Strategies for optimization of short-term genotoxicity tests: the synergistic effect of NADPH and NADH on P450 function in processing pre-mutagens.
Mutagenesis 1990;5(1):51-4.
1990: Patrizia Hrelia; M Scotti; M Morotti; F Vigagni; Moreno Paolini; E Sapigni; Giorgio Cantelli-Forti
Dimethylsulfoxide as modifier of the organospecific mutagenicity of metronidazole in mice.
Teratogenesis, carcinogenesis, and mutagenesis 1990;10(3):263-71.
1989: Moreno Paolini; E Sapigni; Patrizia Hrelia; Giorgio Cantelli-Forti
The synergistic effect of NADPH and NADH on P450 function in processing premutagens.
Pharmacological research : the official journal of the Italian Pharmacological Society 1989;21 Suppl 1():129-30.
1989: Giorgio Cantelli-Forti; M C Guerra; M Scotti; Patrizia Hrelia; Moreno Paolini; Gian Luigi Biagi
Biliary excretion of mutagenic forms of nitroimidazoles in rats.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1989;13():333-9.
1988: Moreno Paolini; E Sapigni; Patrizia Hrelia; S Grilli; G Lattanzi; Giorgio Cantelli-Forti
Improvement of short-term tests for mutagenicity: on the optimal pH for the liver microsomal assay.
Carcinogenesis 1988;9(12):2265-70.
1988: Moreno Paolini; Giorgio Cantelli-Forti; C Bauer
Comparisons between in vivo and in vitro systems: the in vivo equivalent dose concept.
Mutagenesis 1988;3(6):527-31.
1988: Patrizia Hrelia; L Murelli; M Scotti; Moreno Paolini; Giorgio Cantelli-Forti
Organospecific activation of azathioprine in mice: role of liver metabolism in mutation induction.
Carcinogenesis 1988;9(6):1011-5.
1988: Moreno Paolini; E Sapigni; Patrizia Hrelia; S Grilli; Giorgio Cantelli-Forti
Isolation of S9 fractions from mouse and rat with increased enzyme activities after repeated administration of cytochrome P-450 and P-448 inducers.
Mutagenesis 1988;3(3):239-43.
1987: Patrizia Hrelia; L Murelli; Moreno Paolini; E Sapigni; Giorgio Cantelli-Forti
Inducibility of NADPH cytochrome c (P-450) reductase in yeast: role in the bioactivation of nitroimidazo(2,1-b)thiazoles.
Mutagenesis 1987;2(6):425-9.
1987: Giorgio Cantelli-Forti; Moreno Paolini; Patrizia Hrelia; E Sapigni; Gian Luigi Biagi
Effects of metronidazole, azanidazole, and azathioprine on cytochrome P450 and various mono-oxygenase activities in hepatic microsomes from control and induced mice.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1987;11():264-9.
1987: Patrizia Hrelia; L Murelli; Moreno Paolini; Giorgio Cantelli-Forti
In vivo protective role of antioxidants against genotoxicity of metronidazole and azanidazole.
Drugs under experimental and clinical research 1987;13(9):577-83.
1986: Gian Luigi Biagi; Patrizia Hrelia; M C Guerra; Moreno Paolini; A M Barbaro; Giorgio Cantelli-Forti
Structure-activity relationship of nitroimidazo (2,1-b) thiazoles in the Salmonella mutagenicity assay.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1986;9():425-9.